reg-snw-7090

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.251 1.57e-07 3.41e-02 2.63e-02
chia-screen-data-Fav-reg-snw-7090 subnetwork

Genes (25)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
NDUFA4L2 56901 44-2.4772.45921-Yes-
ZBTB16 7704 1-1.3842.25180TF--
RAE1 8480 7-1.5012.342204TF--
[ TLE3 ] 7090 1-0.9742.2511TF--
PHB 5245 82-2.7432.68936-YesYes
SMARCA4 6597 2-1.3812.251114TF--
VARS 7407 60-2.3662.689124TFYes-
GTF2A2 2958 9-1.9382.37741TF--
FBXO22 26263 36-1.7392.459208TF--
APLP2 334 15-2.7322.3894-YesYes
EIF2S2 8894 40-2.9992.45922-YesYes
NCBP1 4686 41-2.5102.45944-YesYes
FTSJ1 24140 43-2.4632.68935-YesYes
VWF 7450 4-2.3812.34058TFYesYes
PRPF4 9128 5-1.5202.342138TF--
CCT7 10574 40-2.3352.45938-Yes-
NFRKB 4798 3-3.1292.25110-YesYes
UBE2S 27338 3-1.3822.34258---
FUS 2521 11-1.9802.41453TF--
CPSF3 51692 43-2.6862.50331-YesYes
HNRNPU 3192 39-2.8692.64433-Yes-
GPS1 2873 86-3.6212.68936TFYesYes
DRG2 1819 15-2.5262.49211-Yes-
POLH 5429 36-2.5862.45924-YesYes
SFPQ 6421 15-2.0512.389142TFYes-

Interactions (28)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
TLE3 7090 UBE2S 27338 pd > reg.ITFP.txt: no annot
PRPF4 9128 UBE2S 27338 pd > reg.ITFP.txt: no annot
GTF2A2 2958 UBE2S 27338 pd > reg.ITFP.txt: no annot
VARS 7407 FBXO22 26263 pd <> reg.ITFP.txt: no annot
NFRKB 4798 SMARCA4 6597 pd < reg.ITFP.txt: no annot
SFPQ 6421 UBE2S 27338 pd > reg.ITFP.txt: no annot
VARS 7407 FTSJ1 24140 pd > reg.ITFP.txt: no annot
PHB 5245 VARS 7407 pd < reg.ITFP.txt: no annot
RAE1 8480 UBE2S 27338 pd > reg.ITFP.txt: no annot
VWF 7450 ZBTB16 7704 pd <> reg.ITFP.txt: no annot
FUS 2521 PRPF4 9128 pd <> reg.ITFP.txt: no annot
PHB 5245 FBXO22 26263 pd < reg.ITFP.txt: no annot
FUS 2521 UBE2S 27338 pd > reg.ITFP.txt: no annot
POLH 5429 FBXO22 26263 pd < reg.ITFP.txt: no annot
SMARCA4 6597 UBE2S 27338 pd > reg.ITFP.txt: no annot
FBXO22 26263 UBE2S 27338 pd > reg.ITFP.txt: no annot
NCBP1 4686 FBXO22 26263 pd < reg.ITFP.txt: no annot
APLP2 334 SFPQ 6421 pd < reg.ITFP.txt: no annot
FUS 2521 HNRNPU 3192 pd > reg.ITFP.txt: no annot
ZBTB16 7704 UBE2S 27338 pd > reg.ITFP.txt: no annot
VARS 7407 UBE2S 27338 pd > reg.ITFP.txt: no annot
EIF2S2 8894 FBXO22 26263 pd < reg.ITFP.txt: no annot
FBXO22 26263 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
RAE1 8480 CPSF3 51692 pd > reg.ITFP.txt: no annot
ZBTB16 7704 RAE1 8480 pd <> reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot
CCT7 10574 FBXO22 26263 pd < reg.ITFP.txt: no annot
DRG2 1819 SMARCA4 6597 pd < reg.ITFP.txt: no annot

Related GO terms (310)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0008380RNA splicing2.88e-062.82e-023.828621165
GO:0000398mRNA splicing, via spliceosome1.54e-051.50e-013.931515128
GO:0003723RNA binding2.91e-052.85e-013.246622247
GO:0005654nucleoplasm3.00e-052.93e-012.1571068876
GO:0010467gene expression3.63e-053.55e-012.546849535
GO:0006406mRNA export from nucleus1.83e-041.00e+004.7353744
GO:0006379mRNA cleavage2.24e-041.00e+006.440229
GO:0060766negative regulation of androgen receptor signaling pathway3.41e-041.00e+006.1502411
GO:0035116embryonic hindlimb morphogenesis9.39e-041.00e+005.4402218
GO:0030529ribonucleoprotein complex1.15e-031.00e+003.8373582
GO:0042802identical protein binding1.78e-031.00e+002.464515354
GO:0005515protein binding2.50e-031.00e+000.770181984124
GO:0004832valine-tRNA ligase activity2.56e-031.00e+008.610111
GO:0002128tRNA nucleoside ribose methylation2.56e-031.00e+008.610111
GO:0008175tRNA methyltransferase activity2.56e-031.00e+008.610111
GO:0006438valyl-tRNA aminoacylation2.56e-031.00e+008.610111
GO:0031124mRNA 3'-end processing3.56e-031.00e+004.4802435
GO:0030900forebrain development3.76e-031.00e+004.4402236
GO:0006369termination of RNA polymerase II transcription4.18e-031.00e+004.3622538
GO:0006396RNA processing4.62e-031.00e+004.2882440
GO:0005846nuclear cap binding complex5.11e-031.00e+007.610112
GO:0002176male germ cell proliferation5.11e-031.00e+007.610112
GO:0035887aortic smooth muscle cell differentiation5.11e-031.00e+007.610122
GO:0019865immunoglobulin binding5.11e-031.00e+007.610112
GO:0010994free ubiquitin chain polymerization5.11e-031.00e+007.610112
GO:0048742regulation of skeletal muscle fiber development5.11e-031.00e+007.610112
GO:0001832blastocyst growth5.11e-031.00e+007.610112
GO:0007403glial cell fate determination5.11e-031.00e+007.610112
GO:0051123RNA polymerase II transcriptional preinitiation complex assembly5.11e-031.00e+007.610112
GO:0007070negative regulation of transcription from RNA polymerase II promoter during mitosis5.11e-031.00e+007.610112
GO:0005634nucleus5.38e-031.00e+000.852151583246
GO:0006310DNA recombination7.15e-031.00e+003.9662850
GO:0002020protease binding7.15e-031.00e+003.9662350
GO:0071001U4/U6 snRNP7.66e-031.00e+007.025113
GO:0046914transition metal ion binding7.66e-031.00e+007.025113
GO:0010424DNA methylation on cytosine within a CG sequence7.66e-031.00e+007.025113
GO:0005850eukaryotic translation initiation factor 2 complex7.66e-031.00e+007.025123
GO:1902177positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway7.66e-031.00e+007.025113
GO:0001835blastocyst hatching7.66e-031.00e+007.025113
GO:0005726perichromatin fibrils7.66e-031.00e+007.025113
GO:0048133male germ-line stem cell asymmetric division7.66e-031.00e+007.025113
GO:0006368transcription elongation from RNA polymerase II promoter7.72e-031.00e+003.9092852
GO:0045892negative regulation of transcription, DNA-templated8.04e-031.00e+002.301417317
GO:0042826histone deacetylase binding9.53e-031.00e+003.7522558
GO:0003407neural retina development1.02e-021.00e+006.610124
GO:0033093Weibel-Palade body1.02e-021.00e+006.610114
GO:0048562embryonic organ morphogenesis1.02e-021.00e+006.610114
GO:0045292mRNA cis splicing, via spliceosome1.02e-021.00e+006.610114
GO:0060318definitive erythrocyte differentiation1.02e-021.00e+006.610114
GO:0031442positive regulation of mRNA 3'-end processing1.02e-021.00e+006.610114
GO:0006290pyrimidine dimer repair1.02e-021.00e+006.610124
GO:0007599hemostasis1.02e-021.00e+006.610114
GO:0007176regulation of epidermal growth factor-activated receptor activity1.02e-021.00e+006.610114
GO:0006366transcription from RNA polymerase II promoter1.03e-021.00e+002.196423341
GO:0006464cellular protein modification process1.05e-021.00e+003.6792461
GO:0047485protein N-terminus binding1.19e-021.00e+003.5872665
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activity1.26e-021.00e+003.5432567
GO:0035519protein K29-linked ubiquitination1.27e-021.00e+006.288125
GO:0070934CRD-mediated mRNA stabilization1.27e-021.00e+006.288125
GO:0005672transcription factor TFIIA complex1.27e-021.00e+006.288115
GO:2000323negative regulation of glucocorticoid receptor signaling pathway1.27e-021.00e+006.288115
GO:0002161aminoacyl-tRNA editing activity1.27e-021.00e+006.288115
GO:0051488activation of anaphase-promoting complex activity1.27e-021.00e+006.288115
GO:0004521endoribonuclease activity1.27e-021.00e+006.288115
GO:0010458exit from mitosis1.27e-021.00e+006.288125
GO:0006398histone mRNA 3'-end processing1.27e-021.00e+006.288115
GO:0070307lens fiber cell development1.27e-021.00e+006.288115
GO:0030957Tat protein binding1.27e-021.00e+006.288115
GO:0006282regulation of DNA repair1.27e-021.00e+006.288125
GO:0044314protein K27-linked ubiquitination1.27e-021.00e+006.288125
GO:0048730epidermis morphogenesis1.27e-021.00e+006.288115
GO:0042382paraspeckles1.27e-021.00e+006.288135
GO:0051138positive regulation of NK T cell differentiation1.27e-021.00e+006.288115
GO:0030308negative regulation of cell growth1.37e-021.00e+003.4802370
GO:0001889liver development1.40e-021.00e+003.4602471
GO:0006281DNA repair1.45e-021.00e+002.529324203
GO:0001649osteoblast differentiation1.52e-021.00e+003.4002574
GO:0050847progesterone receptor signaling pathway1.53e-021.00e+006.025126
GO:0002181cytoplasmic translation1.53e-021.00e+006.025116
GO:0042754negative regulation of circadian rhythm1.53e-021.00e+006.025126
GO:0006346methylation-dependent chromatin silencing1.53e-021.00e+006.025116
GO:0070937CRD-mediated mRNA stability complex1.53e-021.00e+006.025126
GO:0085020protein K6-linked ubiquitination1.53e-021.00e+006.025126
GO:0002199zona pellucida receptor complex1.78e-021.00e+005.802147
GO:00084095'-3' exonuclease activity1.78e-021.00e+005.802127
GO:0007617mating behavior1.78e-021.00e+005.802117
GO:0000339RNA cap binding1.78e-021.00e+005.802117
GO:0001823mesonephros development1.78e-021.00e+005.802117
GO:0000380alternative mRNA splicing, via spliceosome1.78e-021.00e+005.802127
GO:0000731DNA synthesis involved in DNA repair1.78e-021.00e+005.802117
GO:0006301postreplication repair1.78e-021.00e+005.802127
GO:0035136forelimb morphogenesis1.78e-021.00e+005.802117
GO:0005832chaperonin-containing T-complex1.78e-021.00e+005.802147
GO:0061036positive regulation of cartilage development1.78e-021.00e+005.802127
GO:0030198extracellular matrix organization1.82e-021.00e+002.40737221
GO:0005845mRNA cap binding complex2.03e-021.00e+005.610118
GO:0006878cellular copper ion homeostasis2.03e-021.00e+005.610118
GO:0006450regulation of translational fidelity2.03e-021.00e+005.610118
GO:0031011Ino80 complex2.03e-021.00e+005.610138
GO:0010388cullin deneddylation2.03e-021.00e+005.610148
GO:0070182DNA polymerase binding2.03e-021.00e+005.610118
GO:0045778positive regulation of ossification2.03e-021.00e+005.610118
GO:0031091platelet alpha granule2.03e-021.00e+005.610118
GO:0010944negative regulation of transcription by competitive promoter binding2.03e-021.00e+005.610118
GO:0071354cellular response to interleukin-62.28e-021.00e+005.440119
GO:0005847mRNA cleavage and polyadenylation specificity factor complex2.28e-021.00e+005.440139
GO:0010225response to UV-C2.28e-021.00e+005.440129
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process2.28e-021.00e+005.440129
GO:0005739mitochondrion2.37e-021.00e+001.567532659
GO:0001967suckling behavior2.53e-021.00e+005.2881410
GO:0043923positive regulation by host of viral transcription2.53e-021.00e+005.2881110
GO:0005095GTPase inhibitor activity2.53e-021.00e+005.2881110
GO:0071564npBAF complex2.53e-021.00e+005.2881310
GO:0032332positive regulation of chondrocyte differentiation2.78e-021.00e+005.1501111
GO:0008334histone mRNA metabolic process2.78e-021.00e+005.1501111
GO:0071565nBAF complex2.78e-021.00e+005.1501311
GO:0005730nucleolus2.91e-021.00e+001.1687741217
GO:0017025TBP-class protein binding3.03e-021.00e+005.0251112
GO:0070577lysine-acetylated histone binding3.03e-021.00e+005.0251212
GO:0006337nucleosome disassembly3.28e-021.00e+004.9091213
GO:0007597blood coagulation, intrinsic pathway3.28e-021.00e+004.9091213
GO:0016514SWI/SNF complex3.28e-021.00e+004.9091313
GO:0005680anaphase-promoting complex3.28e-021.00e+004.9091213
GO:0031589cell-substrate adhesion3.28e-021.00e+004.9091113
GO:0060347heart trabecula formation3.28e-021.00e+004.9091113
GO:0030902hindbrain development3.53e-021.00e+004.8021214
GO:0043393regulation of protein binding3.53e-021.00e+004.8021214
GO:0016575histone deacetylation3.53e-021.00e+004.8021214
GO:0009880embryonic pattern specification3.53e-021.00e+004.8021114
GO:2000134negative regulation of G1/S transition of mitotic cell cycle3.77e-021.00e+004.7031215
GO:0008135translation factor activity, nucleic acid binding3.77e-021.00e+004.7031415
GO:0000188inactivation of MAPK activity3.77e-021.00e+004.7031115
GO:0045638negative regulation of myeloid cell differentiation3.77e-021.00e+004.7031115
GO:0007339binding of sperm to zona pellucida3.77e-021.00e+004.7031415
GO:0030099myeloid cell differentiation3.77e-021.00e+004.7031115
GO:0070932histone H3 deacetylation3.77e-021.00e+004.7031215
GO:0016607nuclear speck3.85e-021.00e+002.67928122
GO:0005719nuclear euchromatin4.02e-021.00e+004.6101216
GO:0003887DNA-directed DNA polymerase activity4.02e-021.00e+004.6101216
GO:0000792heterochromatin4.27e-021.00e+004.5221117
GO:0005640nuclear outer membrane4.27e-021.00e+004.5221117
GO:0031047gene silencing by RNA4.51e-021.00e+004.4401218
GO:0006378mRNA polyadenylation4.51e-021.00e+004.4401318
GO:0000375RNA splicing, via transesterification reactions4.51e-021.00e+004.4401118
GO:0001105RNA polymerase II transcription coactivator activity4.76e-021.00e+004.3621219
GO:0036464cytoplasmic ribonucleoprotein granule4.76e-021.00e+004.3621119
GO:0044822poly(A) RNA binding4.88e-021.00e+001.289545799
GO:0006913nucleocytoplasmic transport5.00e-021.00e+004.2881220
GO:0070979protein K11-linked ubiquitination5.00e-021.00e+004.2881320
GO:0034660ncRNA metabolic process5.00e-021.00e+004.2881120
GO:0043044ATP-dependent chromatin remodeling5.00e-021.00e+004.2881320
GO:0071897DNA biosynthetic process5.00e-021.00e+004.2881220
GO:0044212transcription regulatory region DNA binding5.13e-021.00e+002.450213143
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic5.25e-021.00e+004.2171221
GO:0043388positive regulation of DNA binding5.25e-021.00e+004.2171221
GO:0051084'de novo' posttranslational protein folding5.49e-021.00e+004.1501422
GO:0034504protein localization to nucleus5.49e-021.00e+004.1501122
GO:0000387spliceosomal snRNP assembly5.49e-021.00e+004.1501122
GO:0045600positive regulation of fat cell differentiation5.49e-021.00e+004.1501122
GO:0030177positive regulation of Wnt signaling pathway5.73e-021.00e+004.0861123
GO:0016604nuclear body5.73e-021.00e+004.0861223
GO:0001103RNA polymerase II repressing transcription factor binding5.73e-021.00e+004.0861223
GO:00063707-methylguanosine mRNA capping5.97e-021.00e+004.0251524
GO:0008180COP9 signalosome5.97e-021.00e+004.0251624
GO:0070534protein K63-linked ubiquitination5.97e-021.00e+004.0251324
GO:0010827regulation of glucose transport6.21e-021.00e+003.9661725
GO:0000976transcription regulatory region sequence-specific DNA binding6.21e-021.00e+003.9661325
GO:0030901midbrain development6.21e-021.00e+003.9661125
GO:0031492nucleosomal DNA binding6.21e-021.00e+003.9661325
GO:0009267cellular response to starvation6.46e-021.00e+003.9091126
GO:0001890placenta development6.46e-021.00e+003.9091226
GO:0016881acid-amino acid ligase activity6.94e-021.00e+003.8021328
GO:0043966histone H3 acetylation6.94e-021.00e+003.8021428
GO:0050885neuromuscular process controlling balance6.94e-021.00e+003.8021128
GO:0045893positive regulation of transcription, DNA-templated7.01e-021.00e+001.636321377
GO:0006418tRNA aminoacylation for protein translation7.17e-021.00e+003.7521429
GO:0008094DNA-dependent ATPase activity7.17e-021.00e+003.7521629
GO:0042733embryonic digit morphogenesis7.17e-021.00e+003.7521229
GO:0042752regulation of circadian rhythm7.17e-021.00e+003.7521529
GO:0006446regulation of translational initiation7.17e-021.00e+003.7521229
GO:0005524ATP binding7.20e-021.00e+001.131537892
GO:0000166nucleotide binding7.39e-021.00e+002.150213176
GO:0050681androgen receptor binding7.41e-021.00e+003.7031230
GO:0004842ubiquitin-protein transferase activity7.61e-021.00e+002.126217179
GO:0007077mitotic nuclear envelope disassembly7.89e-021.00e+003.6101932
GO:0015030Cajal body7.89e-021.00e+003.6101332
GO:0003713transcription coactivator activity7.99e-021.00e+002.086221184
GO:0071407cellular response to organic cyclic compound8.36e-021.00e+003.5221234
GO:0007254JNK cascade8.36e-021.00e+003.5221134
GO:0031093platelet alpha granule lumen8.60e-021.00e+003.4801335
GO:0044297cell body8.60e-021.00e+003.4801535
GO:0000902cell morphogenesis8.60e-021.00e+003.4801535
GO:0050434positive regulation of viral transcription8.60e-021.00e+003.4801535
GO:0003677DNA binding8.82e-021.00e+001.044552947
GO:0008645hexose transport8.83e-021.00e+003.4401836
GO:0051216cartilage development8.83e-021.00e+003.4401136
GO:0003743translation initiation factor activity9.06e-021.00e+003.4001837
GO:0001948glycoprotein binding9.06e-021.00e+003.4001137
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process9.30e-021.00e+003.3621438
GO:0030216keratinocyte differentiation9.30e-021.00e+003.3621138
GO:0048511rhythmic process9.30e-021.00e+003.3621538
GO:0042803protein homodimerization activity9.43e-021.00e+001.453313428
GO:0016032viral process9.43e-021.00e+001.453330428
GO:0019827stem cell maintenance9.53e-021.00e+003.3241439
GO:0009611response to wounding1.00e-011.00e+003.2521241
GO:0003684damaged DNA binding1.00e-011.00e+003.2521141
GO:0004867serine-type endopeptidase inhibitor activity1.02e-011.00e+003.2171142
GO:0001047core promoter binding1.02e-011.00e+003.2171442
GO:0004386helicase activity1.02e-011.00e+003.2171342
GO:0017053transcriptional repressor complex1.02e-011.00e+003.2171242
GO:0051087chaperone binding1.09e-011.00e+003.1181345
GO:0001570vasculogenesis1.09e-011.00e+003.1181245
GO:0002039p53 binding1.09e-011.00e+003.1181445
GO:0000122negative regulation of transcription from RNA polymerase II promoter1.09e-011.00e+001.362329456
GO:0005518collagen binding1.14e-011.00e+003.0551247
GO:0007626locomotory behavior1.14e-011.00e+003.0551147
GO:0008203cholesterol metabolic process1.14e-011.00e+003.0551247
GO:0030097hemopoiesis1.16e-011.00e+003.0251348
GO:0015758glucose transport1.16e-011.00e+003.0251848
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding1.18e-011.00e+002.9951449
GO:0005643nuclear pore1.23e-011.00e+002.93711251
GO:0006338chromatin remodeling1.32e-011.00e+002.8281755
GO:0005681spliceosomal complex1.32e-011.00e+002.8281855
GO:0008584male gonad development1.36e-011.00e+002.7771157
GO:0000785chromatin1.41e-011.00e+002.7271659
GO:0009952anterior/posterior pattern specification1.43e-011.00e+002.7031360
GO:0071013catalytic step 2 spliceosome1.45e-011.00e+002.6791561
GO:0002576platelet degranulation1.47e-011.00e+002.6551362
GO:0007417central nervous system development1.50e-011.00e+002.6321263
GO:0030018Z disc1.52e-011.00e+002.6101364
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.54e-011.00e+002.5871765
GO:0008285negative regulation of cell proliferation1.57e-011.00e+001.496211277
GO:0005178integrin binding1.60e-011.00e+002.5221368
GO:0051082unfolded protein binding1.65e-011.00e+002.4801570
GO:0010951negative regulation of endopeptidase activity1.67e-011.00e+002.4601271
GO:0016363nuclear matrix1.71e-011.00e+002.42011073
GO:0009887organ morphogenesis1.73e-011.00e+002.4001174
GO:0016605PML body1.84e-011.00e+002.3061579
GO:0016020membrane1.89e-011.00e+000.6945561207
GO:0005635nuclear envelope1.92e-011.00e+002.2351683
GO:0003690double-stranded DNA binding1.92e-011.00e+002.2351683
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.94e-011.00e+002.2171584
GO:0016055Wnt signaling pathway2.01e-011.00e+002.1671687
GO:0051260protein homooligomerization2.01e-011.00e+002.1671287
GO:0007165signal transduction2.08e-011.00e+000.923324618
GO:0008201heparin binding2.09e-011.00e+002.1021491
GO:0005737cytoplasm2.10e-011.00e+000.41791272633
GO:0000209protein polyubiquitination2.11e-011.00e+002.0861692
GO:0006511ubiquitin-dependent protein catabolic process2.11e-011.00e+002.0861692
GO:0046872metal ion binding2.12e-011.00e+000.742424934
GO:0006260DNA replication2.15e-011.00e+002.0551994
GO:0007219Notch signaling pathway2.17e-011.00e+002.0401295
GO:0008017microtubule binding2.21e-011.00e+002.0101997
GO:0006457protein folding2.21e-011.00e+002.0101597
GO:0006413translational initiation2.25e-011.00e+001.9801699
GO:0044267cellular protein metabolic process2.27e-011.00e+001.150214352
GO:0031012extracellular matrix2.41e-011.00e+001.86814107
GO:0000790nuclear chromatin2.45e-011.00e+001.84119109
GO:0006397mRNA processing2.47e-011.00e+001.828112110
GO:0042981regulation of apoptotic process2.51e-011.00e+001.80214112
GO:0008022protein C-terminus binding2.57e-011.00e+001.76415115
GO:0007049cell cycle2.57e-011.00e+001.76418115
GO:0005578proteinaceous extracellular matrix2.57e-011.00e+001.76414115
GO:0006355regulation of transcription, DNA-templated2.76e-011.00e+000.713331715
GO:0019904protein domain specific binding2.85e-011.00e+001.58714130
GO:0009897external side of plasma membrane2.87e-011.00e+001.57613131
GO:0006351transcription, DNA-templated2.94e-011.00e+000.5384471076
GO:0003714transcription corepressor activity2.98e-011.00e+001.51215137
GO:0030168platelet activation3.05e-011.00e+001.47015141
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding3.07e-011.00e+001.46017142
GO:0001701in utero embryonic development3.28e-011.00e+001.34317154
GO:0006367transcription initiation from RNA polymerase II promoter3.40e-011.00e+001.279118161
GO:0005874microtubule3.44e-011.00e+001.261110163
GO:0016071mRNA metabolic process3.56e-011.00e+001.200110170
GO:0019221cytokine-mediated signaling pathway3.59e-011.00e+001.183110172
GO:0006412translation3.69e-011.00e+001.134112178
GO:0006954inflammatory response3.80e-011.00e+001.07813185
GO:0005975carbohydrate metabolic process3.82e-011.00e+001.070110186
GO:0016567protein ubiquitination3.85e-011.00e+001.055114188
GO:0016070RNA metabolic process3.85e-011.00e+001.055110188
GO:0005856cytoskeleton3.88e-011.00e+001.04018190
GO:0005743mitochondrial inner membrane4.00e-011.00e+000.98719197
GO:0005525GTP binding4.00e-011.00e+000.987112197
GO:0043065positive regulation of apoptotic process4.07e-011.00e+000.95117202
GO:0006357regulation of transcription from RNA polymerase II promoter4.09e-011.00e+000.944114203
GO:0008134transcription factor binding4.18e-011.00e+000.902110209
GO:0019899enzyme binding4.20e-011.00e+000.89517210
GO:0043234protein complex4.20e-011.00e+000.895113210
GO:0030054cell junction4.32e-011.00e+000.84115218
GO:0006200ATP catabolic process4.33e-011.00e+000.835113219
GO:0007186G-protein coupled receptor signaling pathway4.48e-011.00e+000.77014229
GO:0007155cell adhesion4.69e-011.00e+000.67918244
GO:0005829cytosol4.93e-011.00e+000.1285881787
GO:0046982protein heterodimerization activity4.98e-011.00e+000.560111265
GO:0045944positive regulation of transcription from RNA polymerase II promoter4.98e-011.00e+000.279229644
GO:0009986cell surface5.31e-011.00e+000.42515291
GO:0000278mitotic cell cycle5.59e-011.00e+000.315128314
GO:0055085transmembrane transport5.76e-011.00e+000.248113329
GO:0007596blood coagulation5.87e-011.00e+000.204113339
GO:0070062extracellular vesicular exosome6.26e-011.00e+00-0.0714511641
GO:0005783endoplasmic reticulum6.31e-011.00e+000.036112381
GO:0006915apoptotic process6.59e-011.00e+00-0.073115411
GO:0005887integral component of plasma membrane7.81e-011.00e+00-0.55818575
GO:0003700sequence-specific DNA binding transcription factor activity7.85e-011.00e+00-0.575122582
GO:0005615extracellular space8.22e-011.00e+00-0.737115651
GO:0005576extracellular region8.28e-011.00e+00-0.763115663
GO:0008270zinc ion binding8.56e-011.00e+00-0.896139727
GO:0005886plasma membrane8.61e-011.00e+00-0.6063461784
GO:0044281small molecule metabolic process8.96e-011.00e+00-1.112135844
GO:0016021integral component of membrane9.86e-011.00e+00-1.9661191526