reg-snw-27338

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.342 5.13e-08 1.84e-02 1.50e-02
chia-screen-data-Fav-reg-snw-27338 subnetwork

Genes (19)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
NDUFA4L2 56901 44-2.4772.45921-Yes-
RAE1 8480 7-1.5012.342204TF--
PHB 5245 82-2.7432.68936-YesYes
VARS 7407 60-2.3662.689124TFYes-
GTF2A2 2958 9-1.9382.37741TF--
FBXO22 26263 36-1.7392.459208TF--
APLP2 334 15-2.7322.3894-YesYes
NCBP1 4686 41-2.5102.45944-YesYes
EIF2S2 8894 40-2.9992.45922-YesYes
FTSJ1 24140 43-2.4632.68935-YesYes
PRPF4 9128 5-1.5202.342138TF--
CCT7 10574 40-2.3352.45938-Yes-
[ UBE2S ] 27338 3-1.3822.34258---
FUS 2521 11-1.9802.41453TF--
HNRNPU 3192 39-2.8692.64433-Yes-
CPSF3 51692 43-2.6862.50331-YesYes
GPS1 2873 86-3.6212.68936TFYesYes
POLH 5429 36-2.5862.45924-YesYes
SFPQ 6421 15-2.0512.389142TFYes-

Interactions (21)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
NCBP1 4686 FBXO22 26263 pd < reg.ITFP.txt: no annot
APLP2 334 SFPQ 6421 pd < reg.ITFP.txt: no annot
FUS 2521 HNRNPU 3192 pd > reg.ITFP.txt: no annot
PRPF4 9128 UBE2S 27338 pd > reg.ITFP.txt: no annot
GTF2A2 2958 UBE2S 27338 pd > reg.ITFP.txt: no annot
VARS 7407 FBXO22 26263 pd <> reg.ITFP.txt: no annot
SFPQ 6421 UBE2S 27338 pd > reg.ITFP.txt: no annot
VARS 7407 FTSJ1 24140 pd > reg.ITFP.txt: no annot
PHB 5245 VARS 7407 pd < reg.ITFP.txt: no annot
VARS 7407 UBE2S 27338 pd > reg.ITFP.txt: no annot
EIF2S2 8894 FBXO22 26263 pd < reg.ITFP.txt: no annot
RAE1 8480 UBE2S 27338 pd > reg.ITFP.txt: no annot
FBXO22 26263 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
FUS 2521 PRPF4 9128 pd <> reg.ITFP.txt: no annot
RAE1 8480 CPSF3 51692 pd > reg.ITFP.txt: no annot
PHB 5245 FBXO22 26263 pd < reg.ITFP.txt: no annot
FUS 2521 UBE2S 27338 pd > reg.ITFP.txt: no annot
POLH 5429 FBXO22 26263 pd < reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot
CCT7 10574 FBXO22 26263 pd < reg.ITFP.txt: no annot
FBXO22 26263 UBE2S 27338 pd > reg.ITFP.txt: no annot

Related GO terms (201)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0008380RNA splicing4.81e-074.69e-034.224621165
GO:0010467gene expression3.40e-063.32e-022.942849535
GO:0000398mRNA splicing, via spliceosome3.59e-063.51e-024.327515128
GO:0003723RNA binding5.07e-064.95e-023.642622247
GO:0005654nucleoplasm1.46e-051.42e-012.401968876
GO:0006406mRNA export from nucleus7.87e-057.68e-015.1313744
GO:0006379mRNA cleavage1.28e-041.00e+006.836229
GO:0030529ribonucleoprotein complex5.02e-041.00e+004.2333582
GO:0004832valine-tRNA ligase activity1.95e-031.00e+009.005111
GO:0002128tRNA nucleoside ribose methylation1.95e-031.00e+009.005111
GO:0008175tRNA methyltransferase activity1.95e-031.00e+009.005111
GO:0006438valyl-tRNA aminoacylation1.95e-031.00e+009.005111
GO:0031124mRNA 3'-end processing2.05e-031.00e+004.8762435
GO:0006369termination of RNA polymerase II transcription2.42e-031.00e+004.7582538
GO:0006396RNA processing2.68e-031.00e+004.6842440
GO:0010994free ubiquitin chain polymerization3.89e-031.00e+008.005112
GO:0048742regulation of skeletal muscle fiber development3.89e-031.00e+008.005112
GO:0005846nuclear cap binding complex3.89e-031.00e+008.005112
GO:0002176male germ cell proliferation3.89e-031.00e+008.005112
GO:0051123RNA polymerase II transcriptional preinitiation complex assembly3.89e-031.00e+008.005112
GO:0006368transcription elongation from RNA polymerase II promoter4.49e-031.00e+004.3052852
GO:0042826histone deacetylase binding5.56e-031.00e+004.1472558
GO:0005850eukaryotic translation initiation factor 2 complex5.83e-031.00e+007.421123
GO:0071001U4/U6 snRNP5.83e-031.00e+007.421113
GO:1902177positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway5.83e-031.00e+007.421113
GO:0046914transition metal ion binding5.83e-031.00e+007.421113
GO:0006464cellular protein modification process6.13e-031.00e+004.0752461
GO:0045292mRNA cis splicing, via spliceosome7.76e-031.00e+007.005114
GO:0031442positive regulation of mRNA 3'-end processing7.76e-031.00e+007.005114
GO:0006290pyrimidine dimer repair7.76e-031.00e+007.005124
GO:0007176regulation of epidermal growth factor-activated receptor activity7.76e-031.00e+007.005114
GO:0001649osteoblast differentiation8.91e-031.00e+003.7962574
GO:0004521endoribonuclease activity9.69e-031.00e+006.684115
GO:0010458exit from mitosis9.69e-031.00e+006.684125
GO:0006398histone mRNA 3'-end processing9.69e-031.00e+006.684115
GO:0035519protein K29-linked ubiquitination9.69e-031.00e+006.684125
GO:0070934CRD-mediated mRNA stabilization9.69e-031.00e+006.684125
GO:0005672transcription factor TFIIA complex9.69e-031.00e+006.684115
GO:0006282regulation of DNA repair9.69e-031.00e+006.684125
GO:2000323negative regulation of glucocorticoid receptor signaling pathway9.69e-031.00e+006.684115
GO:0044314protein K27-linked ubiquitination9.69e-031.00e+006.684125
GO:0002161aminoacyl-tRNA editing activity9.69e-031.00e+006.684115
GO:0051488activation of anaphase-promoting complex activity9.69e-031.00e+006.684115
GO:0042382paraspeckles9.69e-031.00e+006.684135
GO:0050847progesterone receptor signaling pathway1.16e-021.00e+006.421126
GO:0002181cytoplasmic translation1.16e-021.00e+006.421116
GO:0042754negative regulation of circadian rhythm1.16e-021.00e+006.421126
GO:0085020protein K6-linked ubiquitination1.16e-021.00e+006.421126
GO:0070937CRD-mediated mRNA stability complex1.16e-021.00e+006.421126
GO:0002199zona pellucida receptor complex1.35e-021.00e+006.198147
GO:0000731DNA synthesis involved in DNA repair1.35e-021.00e+006.198117
GO:0006301postreplication repair1.35e-021.00e+006.198127
GO:00084095'-3' exonuclease activity1.35e-021.00e+006.198127
GO:0007617mating behavior1.35e-021.00e+006.198117
GO:0000339RNA cap binding1.35e-021.00e+006.198117
GO:0005832chaperonin-containing T-complex1.35e-021.00e+006.198147
GO:0000380alternative mRNA splicing, via spliceosome1.35e-021.00e+006.198127
GO:0005845mRNA cap binding complex1.55e-021.00e+006.005118
GO:0006878cellular copper ion homeostasis1.55e-021.00e+006.005118
GO:0006450regulation of translational fidelity1.55e-021.00e+006.005118
GO:0010944negative regulation of transcription by competitive promoter binding1.55e-021.00e+006.005118
GO:0010388cullin deneddylation1.55e-021.00e+006.005148
GO:0044822poly(A) RNA binding1.60e-021.00e+001.685545799
GO:0010225response to UV-C1.74e-021.00e+005.836129
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process1.74e-021.00e+005.836129
GO:0071354cellular response to interleukin-61.74e-021.00e+005.836119
GO:0005847mRNA cleavage and polyadenylation specificity factor complex1.74e-021.00e+005.836139
GO:0005515protein binding1.92e-021.00e+000.696131984124
GO:0001967suckling behavior1.93e-021.00e+005.6841410
GO:0005095GTPase inhibitor activity1.93e-021.00e+005.6841110
GO:0060766negative regulation of androgen receptor signaling pathway2.12e-021.00e+005.5461411
GO:0008334histone mRNA metabolic process2.12e-021.00e+005.5461111
GO:0017025TBP-class protein binding2.31e-021.00e+005.4211112
GO:0005634nucleus2.35e-021.00e+000.800111583246
GO:0005680anaphase-promoting complex2.50e-021.00e+005.3051213
GO:0043393regulation of protein binding2.69e-021.00e+005.1981214
GO:0016575histone deacetylation2.69e-021.00e+005.1981214
GO:0006366transcription from RNA polymerase II promoter2.70e-021.00e+002.177323341
GO:0008135translation factor activity, nucleic acid binding2.88e-021.00e+005.0991415
GO:0000188inactivation of MAPK activity2.88e-021.00e+005.0991115
GO:0007339binding of sperm to zona pellucida2.88e-021.00e+005.0991415
GO:0070932histone H3 deacetylation2.88e-021.00e+005.0991215
GO:0042802identical protein binding2.97e-021.00e+002.123315354
GO:0003887DNA-directed DNA polymerase activity3.07e-021.00e+005.0051216
GO:0044212transcription regulatory region DNA binding3.09e-021.00e+002.846213143
GO:0005640nuclear outer membrane3.26e-021.00e+004.9181117
GO:0031047gene silencing by RNA3.45e-021.00e+004.8361218
GO:0006378mRNA polyadenylation3.45e-021.00e+004.8361318
GO:0000375RNA splicing, via transesterification reactions3.45e-021.00e+004.8361118
GO:0005739mitochondrion3.53e-021.00e+001.641432659
GO:0036464cytoplasmic ribonucleoprotein granule3.64e-021.00e+004.7581119
GO:0006913nucleocytoplasmic transport3.82e-021.00e+004.6841220
GO:0070979protein K11-linked ubiquitination3.82e-021.00e+004.6841320
GO:0071897DNA biosynthetic process3.82e-021.00e+004.6841220
GO:0034660ncRNA metabolic process3.82e-021.00e+004.6841120
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic4.01e-021.00e+004.6131221
GO:0051084'de novo' posttranslational protein folding4.20e-021.00e+004.5461422
GO:0000387spliceosomal snRNP assembly4.20e-021.00e+004.5461122
GO:0001103RNA polymerase II repressing transcription factor binding4.39e-021.00e+004.4821223
GO:0000166nucleotide binding4.52e-021.00e+002.546213176
GO:00063707-methylguanosine mRNA capping4.57e-021.00e+004.4211524
GO:0008180COP9 signalosome4.57e-021.00e+004.4211624
GO:0070534protein K63-linked ubiquitination4.57e-021.00e+004.4211324
GO:0004842ubiquitin-protein transferase activity4.66e-021.00e+002.522217179
GO:0030901midbrain development4.76e-021.00e+004.3621125
GO:0010827regulation of glucose transport4.76e-021.00e+004.3621725
GO:0000976transcription regulatory region sequence-specific DNA binding4.76e-021.00e+004.3621325
GO:0016032viral process4.81e-021.00e+001.849330428
GO:0009267cellular response to starvation4.94e-021.00e+004.3051126
GO:0050885neuromuscular process controlling balance5.31e-021.00e+004.1981128
GO:0016881acid-amino acid ligase activity5.31e-021.00e+004.1981328
GO:0006418tRNA aminoacylation for protein translation5.50e-021.00e+004.1471429
GO:0042752regulation of circadian rhythm5.50e-021.00e+004.1471529
GO:0006446regulation of translational initiation5.50e-021.00e+004.1471229
GO:0006281DNA repair5.83e-021.00e+002.340224203
GO:0007077mitotic nuclear envelope disassembly6.05e-021.00e+004.0051932
GO:0015030Cajal body6.05e-021.00e+004.0051332
GO:0071407cellular response to organic cyclic compound6.42e-021.00e+003.9181234
GO:0007254JNK cascade6.42e-021.00e+003.9181134
GO:0050434positive regulation of viral transcription6.60e-021.00e+003.8761535
GO:0044297cell body6.60e-021.00e+003.8761535
GO:0008645hexose transport6.78e-021.00e+003.8361836
GO:0030900forebrain development6.78e-021.00e+003.8361236
GO:0003743translation initiation factor activity6.97e-021.00e+003.7961837
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process7.15e-021.00e+003.7581438
GO:0048511rhythmic process7.15e-021.00e+003.7581538
GO:0003684damaged DNA binding7.69e-021.00e+003.6481141
GO:0005730nucleolus7.80e-021.00e+001.0785741217
GO:0004867serine-type endopeptidase inhibitor activity7.87e-021.00e+003.6131142
GO:0001047core promoter binding7.87e-021.00e+003.6131442
GO:0008203cholesterol metabolic process8.77e-021.00e+003.4511247
GO:0007626locomotory behavior8.77e-021.00e+003.4511147
GO:0005524ATP binding8.88e-021.00e+001.205437892
GO:0015758glucose transport8.95e-021.00e+003.4211848
GO:0006310DNA recombination9.30e-021.00e+003.3621850
GO:0005643nuclear pore9.48e-021.00e+003.33311251
GO:0005681spliceosomal complex1.02e-011.00e+003.2241855
GO:0008584male gonad development1.05e-011.00e+003.1731157
GO:0000785chromatin1.09e-011.00e+003.1231659
GO:0005737cytoplasm1.12e-011.00e+000.64381272633
GO:0071013catalytic step 2 spliceosome1.12e-011.00e+003.0751561
GO:0030018Z disc1.18e-011.00e+003.0051364
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.19e-011.00e+002.9831765
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activity1.23e-011.00e+002.9391567
GO:0045892negative regulation of transcription, DNA-templated1.25e-011.00e+001.697217317
GO:0030308negative regulation of cell growth1.28e-011.00e+002.8761370
GO:0051082unfolded protein binding1.28e-011.00e+002.8761570
GO:0010951negative regulation of endopeptidase activity1.30e-011.00e+002.8561271
GO:0016363nuclear matrix1.33e-011.00e+002.81611073
GO:0044267cellular protein metabolic process1.48e-011.00e+001.546214352
GO:0005635nuclear envelope1.50e-011.00e+002.6301683
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.52e-011.00e+002.6131584
GO:0008201heparin binding1.63e-011.00e+002.4981491
GO:0000209protein polyubiquitination1.65e-011.00e+002.4821692
GO:0006511ubiquitin-dependent protein catabolic process1.65e-011.00e+002.4821692
GO:0006260DNA replication1.68e-011.00e+002.4511994
GO:0008017microtubule binding1.73e-011.00e+002.4061997
GO:0006457protein folding1.73e-011.00e+002.4061597
GO:0006413translational initiation1.76e-011.00e+002.3761699
GO:0006397mRNA processing1.94e-011.00e+002.224112110
GO:0042981regulation of apoptotic process1.97e-011.00e+002.19814112
GO:0007049cell cycle2.02e-011.00e+002.16018115
GO:0016607nuclear speck2.13e-011.00e+002.07518122
GO:0000122negative regulation of transcription from RNA polymerase II promoter2.22e-011.00e+001.173229456
GO:0001701in utero embryonic development2.61e-011.00e+001.73917154
GO:0006367transcription initiation from RNA polymerase II promoter2.71e-011.00e+001.675118161
GO:0046872metal ion binding2.71e-011.00e+000.723324934
GO:0005874microtubule2.74e-011.00e+001.657110163
GO:0003677DNA binding2.78e-011.00e+000.703352947
GO:0016071mRNA metabolic process2.84e-011.00e+001.596110170
GO:0019221cytokine-mediated signaling pathway2.87e-011.00e+001.579110172
GO:0006412translation2.95e-011.00e+001.530112178
GO:0003713transcription coactivator activity3.04e-011.00e+001.482121184
GO:0005975carbohydrate metabolic process3.06e-011.00e+001.466110186
GO:0016070RNA metabolic process3.09e-011.00e+001.451110188
GO:0005856cytoskeleton3.12e-011.00e+001.43618190
GO:0005743mitochondrial inner membrane3.21e-011.00e+001.38319197
GO:0008134transcription factor binding3.37e-011.00e+001.298110209
GO:0019899enzyme binding3.39e-011.00e+001.29117210
GO:0030054cell junction3.49e-011.00e+001.23715218
GO:0030198extracellular matrix organization3.53e-011.00e+001.21817221
GO:0007186G-protein coupled receptor signaling pathway3.63e-011.00e+001.16614229
GO:0046982protein heterodimerization activity4.07e-011.00e+000.956111265
GO:0008285negative regulation of cell proliferation4.21e-011.00e+000.892111277
GO:0016020membrane4.23e-011.00e+000.3533561207
GO:0009986cell surface4.37e-011.00e+000.82115291
GO:0000278mitotic cell cycle4.63e-011.00e+000.711128314
GO:0005829cytosol4.69e-011.00e+000.2024881787
GO:0055085transmembrane transport4.79e-011.00e+000.644113329
GO:0045893positive regulation of transcription, DNA-templated5.27e-011.00e+000.447121377
GO:0042803protein homodimerization activity5.74e-011.00e+000.264113428
GO:0070062extracellular vesicular exosome6.42e-011.00e+00-0.0903511641
GO:0005887integral component of plasma membrane6.85e-011.00e+00-0.16218575
GO:0007165signal transduction7.12e-011.00e+00-0.266124618
GO:0045944positive regulation of transcription from RNA polymerase II promoter7.27e-011.00e+00-0.325129644
GO:0006355regulation of transcription, DNA-templated7.65e-011.00e+00-0.476131715
GO:0008270zinc ion binding7.70e-011.00e+00-0.500139727
GO:0044281small molecule metabolic process8.21e-011.00e+00-0.716135844
GO:0005886plasma membrane8.87e-011.00e+00-0.7952461784
GO:0006351transcription, DNA-templated8.91e-011.00e+00-1.0661471076
GO:0016021integral component of membrane9.61e-011.00e+00-1.5701191526