int-snw-6102

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.830	1.90e-15	5.16e-04	3.55e-03

chia-screen-data-Fav-int-snw-6102 subnetwork

Genes (20)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
MED19	219541	30	-2.657	3.449	115	Yes	-
RHOA	387	5	-2.408	2.845	151	Yes	Yes
ANXA4	307	7	-2.478	3.062	15	Yes	Yes
MED28	80306	16	-2.404	3.216	80	Yes	-
YAP1	10413	94	-4.256	3.538	53	Yes	-
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
TPR	7175	18	-2.638	3.072	28	Yes	Yes
APLP2	334	12	-2.732	3.206	35	Yes	Yes
PSMD2	5708	47	-4.172	3.157	386	Yes	Yes
TBC1D10A	83874	8	-2.544	2.989	26	Yes	-
ZFP36	7538	10	-2.968	2.869	24	Yes	Yes
LUC7L3	51747	33	-3.523	3.449	18	Yes	-
NFKB1	4790	9	-2.123	2.870	263	Yes	-
MED24	9862	6	-2.482	3.033	39	Yes	-
MED12	9968	14	-2.465	3.206	65	Yes	-
[ RP2 ]	6102	1	-0.649	2.830	5	-	-
MED14	9282	6	-2.420	3.137	49	Yes	-
NFRKB	4798	48	-3.129	3.108	23	Yes	Yes
YY1	7528	24	-2.572	3.120	114	Yes	Yes
DDIT3	1649	60	-2.825	3.504	343	Yes	Yes

Interactions (26)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
MED28	80306	MED19	219541	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct
MED24	9862	MED19	219541	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct
YAP1	10413	MED28	80306	pp	--	int.I2D: MINT; int.Mint: MI:0915(physical association)
MED24	9862	MED28	80306	pp	--	int.I2D: BioGrid
NFKB1	4790	ZFP36	7538	pp	--	int.I2D: BioGrid
APLP2	334	RP2	6102	pp	--	int.I2D: IntAct_Mouse
DDIT3	1649	NFKB1	4790	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
MED14	9282	MED12	9968	pp	--	int.I2D: BioGrid
APLP2	334	MED12	9968	pp	--	int.I2D: MINT; int.Mint: MI:0407(direct interaction)
MED14	9282	MED19	219541	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct
RHOA	387	PSMD2	5708	pp	--	int.I2D: BioGrid_Yeast
NFKB1	4790	YY1	7528	pp	--	int.Intact: MI:0915(physical association)
APLP2	334	RHOA	387	pp	--	int.I2D: IntAct_Mouse
NFKB1	4790	NFRKB	4798	pp	--	int.I2D: BCI, HPRD; int.Ravasi: -; int.HPRD: in vitro
NFRKB	4798	YY1	7528	pp	--	int.I2D: BioGrid
MED12	9968	MED28	80306	pp	--	int.I2D: BioGrid
MED12	9968	MED19	219541	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct
APLP2	334	NFKB1	4790	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
MED24	9862	MED12	9968	pp	--	int.I2D: BioGrid
LUC7L3	51747	MED19	219541	pp	--	int.Intact: MI:0914(association); int.I2D: IntAct
NFKB1	4790	TPR	7175	pp	--	int.I2D: MINT; int.Mint: MI:0915(physical association)
NFRKB	4798	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
MED14	9282	MED28	80306	pp	--	int.I2D: BioGrid
RHOA	387	TBC1D10A	83874	pp	--	int.I2D: BioGrid_Yeast
ANXA4	307	NFKB1	4790	pp	--	int.I2D: BioGrid, INNATEDB
MED14	9282	MED24	9862	pp	--	int.I2D: BioGrid

Related GO terms (373)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0016592	mediator complex	9.43e-10	1.36e-05	6.687	5	10	35
GO:0001104	RNA polymerase II transcription cofactor activity	1.07e-07	1.55e-03	6.450	4	8	33
GO:0019827	stem cell maintenance	4.62e-07	6.66e-03	5.940	4	7	47
GO:0030518	intracellular steroid hormone receptor signaling pathway	8.22e-07	1.19e-02	7.272	3	6	14
GO:0042809	vitamin D receptor binding	1.03e-06	1.48e-02	7.172	3	6	15
GO:0044212	transcription regulatory region DNA binding	2.72e-06	3.92e-02	4.424	5	17	168
GO:0005654	nucleoplasm	5.73e-06	8.27e-02	2.585	9	64	1082
GO:0046966	thyroid hormone receptor binding	5.81e-06	8.38e-02	6.379	3	6	26
GO:0030521	androgen receptor signaling pathway	2.35e-05	3.39e-01	5.722	3	5	41
GO:0006357	regulation of transcription from RNA polymerase II promoter	2.45e-05	3.53e-01	3.772	5	23	264
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity	2.72e-05	3.92e-01	5.653	3	7	43
GO:0003712	transcription cofactor activity	2.91e-05	4.20e-01	5.620	3	8	44
GO:0005634	nucleus	8.37e-05	1.00e+00	1.247	15	159	4559
GO:0006367	transcription initiation from RNA polymerase II promoter	1.06e-04	1.00e+00	3.971	4	22	184
GO:0003729	mRNA binding	1.28e-04	1.00e+00	4.909	3	4	72
GO:0042789	mRNA transcription from RNA polymerase II promoter	1.41e-04	1.00e+00	6.794	2	2	13
GO:0031011	Ino80 complex	1.65e-04	1.00e+00	6.687	2	6	14
GO:0010467	gene expression	2.16e-04	1.00e+00	2.693	6	45	669
GO:0003713	transcription coactivator activity	2.80e-04	1.00e+00	3.605	4	24	237
GO:0045893	positive regulation of transcription, DNA-templated	4.02e-04	1.00e+00	2.915	5	24	478
GO:0005515	protein binding	5.64e-04	1.00e+00	0.938	16	198	6024
GO:0042594	response to starvation	8.29e-04	1.00e+00	5.540	2	4	31
GO:0003677	DNA binding	8.73e-04	1.00e+00	2.051	7	49	1218
GO:0031072	heat shock protein binding	9.40e-04	1.00e+00	5.450	2	2	33
GO:0006974	cellular response to DNA damage stimulus	1.13e-03	1.00e+00	3.841	3	7	151
GO:1901673	regulation of spindle assembly involved in mitosis	1.39e-03	1.00e+00	9.494	1	1	1
GO:0043578	nuclear matrix organization	1.39e-03	1.00e+00	9.494	1	1	1
GO:2000016	negative regulation of determination of dorsal identity	1.39e-03	1.00e+00	9.494	1	1	1
GO:0010965	regulation of mitotic sister chromatid separation	1.39e-03	1.00e+00	9.494	1	1	1
GO:0045083	negative regulation of interleukin-12 biosynthetic process	1.39e-03	1.00e+00	9.494	1	1	1
GO:0006404	RNA import into nucleus	1.39e-03	1.00e+00	9.494	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	1.39e-03	1.00e+00	9.494	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	1.39e-03	1.00e+00	9.494	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	1.39e-03	1.00e+00	9.494	1	1	1
GO:0060795	cell fate commitment involved in formation of primary germ layer	1.39e-03	1.00e+00	9.494	1	1	1
GO:0061383	trabecula morphogenesis	1.39e-03	1.00e+00	9.494	1	1	1
GO:0031453	positive regulation of heterochromatin assembly	1.39e-03	1.00e+00	9.494	1	1	1
GO:1990075	periciliary membrane compartment	1.39e-03	1.00e+00	9.494	1	1	1
GO:0003714	transcription corepressor activity	1.81e-03	1.00e+00	3.603	3	11	178
GO:0004872	receptor activity	2.14e-03	1.00e+00	3.517	3	8	189
GO:0006366	transcription from RNA polymerase II promoter	2.35e-03	1.00e+00	2.783	4	30	419
GO:0050728	negative regulation of inflammatory response	2.69e-03	1.00e+00	4.687	2	3	56
GO:0060242	contact inhibition	2.77e-03	1.00e+00	8.494	1	1	2
GO:0031990	mRNA export from nucleus in response to heat stress	2.77e-03	1.00e+00	8.494	1	2	2
GO:0006403	RNA localization	2.77e-03	1.00e+00	8.494	1	1	2
GO:2000483	negative regulation of interleukin-8 secretion	2.77e-03	1.00e+00	8.494	1	1	2
GO:0009786	regulation of asymmetric cell division	2.77e-03	1.00e+00	8.494	1	1	2
GO:0070840	dynein complex binding	2.77e-03	1.00e+00	8.494	1	1	2
GO:0046832	negative regulation of RNA export from nucleus	2.77e-03	1.00e+00	8.494	1	1	2
GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	2.77e-03	1.00e+00	8.494	1	1	2
GO:0034696	response to prostaglandin F	2.77e-03	1.00e+00	8.494	1	1	2
GO:0000189	MAPK import into nucleus	2.77e-03	1.00e+00	8.494	1	1	2
GO:0044324	regulation of transcription involved in anterior/posterior axis specification	2.77e-03	1.00e+00	8.494	1	1	2
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.77e-03	1.00e+00	2.192	5	41	789
GO:0046914	transition metal ion binding	4.15e-03	1.00e+00	7.909	1	1	3
GO:0042306	regulation of protein import into nucleus	4.15e-03	1.00e+00	7.909	1	2	3
GO:0060913	cardiac cell fate determination	4.15e-03	1.00e+00	7.909	1	1	3
GO:1900127	positive regulation of hyaluronan biosynthetic process	4.15e-03	1.00e+00	7.909	1	1	3
GO:0090245	axis elongation involved in somitogenesis	4.15e-03	1.00e+00	7.909	1	1	3
GO:0050779	RNA destabilization	4.15e-03	1.00e+00	7.909	1	1	3
GO:0010956	negative regulation of calcidiol 1-monooxygenase activity	4.15e-03	1.00e+00	7.909	1	1	3
GO:0033256	I-kappaB/NF-kappaB complex	4.15e-03	1.00e+00	7.909	1	1	3
GO:0006405	RNA export from nucleus	4.15e-03	1.00e+00	7.909	1	2	3
GO:0033688	regulation of osteoblast proliferation	4.15e-03	1.00e+00	7.909	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	4.15e-03	1.00e+00	7.909	1	1	3
GO:0008134	transcription factor binding	4.31e-03	1.00e+00	3.160	3	18	242
GO:0032680	regulation of tumor necrosis factor production	5.54e-03	1.00e+00	7.494	1	1	4
GO:0014044	Schwann cell development	5.54e-03	1.00e+00	7.494	1	1	4
GO:0032375	negative regulation of cholesterol transport	5.54e-03	1.00e+00	7.494	1	1	4
GO:0038027	apolipoprotein A-I-mediated signaling pathway	5.54e-03	1.00e+00	7.494	1	1	4
GO:0010957	negative regulation of vitamin D biosynthetic process	5.54e-03	1.00e+00	7.494	1	1	4
GO:0051151	negative regulation of smooth muscle cell differentiation	5.54e-03	1.00e+00	7.494	1	1	4
GO:0032269	negative regulation of cellular protein metabolic process	5.54e-03	1.00e+00	7.494	1	1	4
GO:2000630	positive regulation of miRNA metabolic process	5.54e-03	1.00e+00	7.494	1	1	4
GO:0006999	nuclear pore organization	5.54e-03	1.00e+00	7.494	1	1	4
GO:0044615	nuclear pore nuclear basket	5.54e-03	1.00e+00	7.494	1	1	4
GO:0001714	endodermal cell fate specification	6.92e-03	1.00e+00	7.172	1	1	5
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	6.92e-03	1.00e+00	7.172	1	1	5
GO:0019957	C-C chemokine binding	6.92e-03	1.00e+00	7.172	1	1	5
GO:0043620	regulation of DNA-templated transcription in response to stress	6.92e-03	1.00e+00	7.172	1	1	5
GO:0007023	post-chaperonin tubulin folding pathway	6.92e-03	1.00e+00	7.172	1	2	5
GO:0010884	positive regulation of lipid storage	6.92e-03	1.00e+00	7.172	1	1	5
GO:0035925	mRNA 3'-UTR AU-rich region binding	6.92e-03	1.00e+00	7.172	1	1	5
GO:0010793	regulation of mRNA export from nucleus	6.92e-03	1.00e+00	7.172	1	1	5
GO:0070849	response to epidermal growth factor	6.92e-03	1.00e+00	7.172	1	1	5
GO:0007176	regulation of epidermal growth factor-activated receptor activity	6.92e-03	1.00e+00	7.172	1	1	5
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	7.06e-03	1.00e+00	2.339	4	37	570
GO:0004859	phospholipase inhibitor activity	8.29e-03	1.00e+00	6.909	1	1	6
GO:0036089	cleavage furrow formation	8.29e-03	1.00e+00	6.909	1	2	6
GO:0046825	regulation of protein export from nucleus	9.67e-03	1.00e+00	6.687	1	2	7
GO:0071354	cellular response to interleukin-6	9.67e-03	1.00e+00	6.687	1	2	7
GO:0043931	ossification involved in bone maturation	9.67e-03	1.00e+00	6.687	1	1	7
GO:0043297	apical junction assembly	9.67e-03	1.00e+00	6.687	1	1	7
GO:0006355	regulation of transcription, DNA-templated	1.01e-02	1.00e+00	1.855	5	43	997
GO:0097202	activation of cysteine-type endopeptidase activity	1.10e-02	1.00e+00	6.494	1	1	8
GO:0051292	nuclear pore complex assembly	1.10e-02	1.00e+00	6.494	1	4	8
GO:0007617	mating behavior	1.10e-02	1.00e+00	6.494	1	1	8
GO:0001955	blood vessel maturation	1.10e-02	1.00e+00	6.494	1	1	8
GO:0071316	cellular response to nicotine	1.10e-02	1.00e+00	6.494	1	1	8
GO:0035457	cellular response to interferon-alpha	1.10e-02	1.00e+00	6.494	1	1	8
GO:0006183	GTP biosynthetic process	1.10e-02	1.00e+00	6.494	1	1	8
GO:0042405	nuclear inclusion body	1.24e-02	1.00e+00	6.324	1	2	9
GO:0000975	regulatory region DNA binding	1.24e-02	1.00e+00	6.324	1	2	9
GO:0010225	response to UV-C	1.24e-02	1.00e+00	6.324	1	2	9
GO:0006228	UTP biosynthetic process	1.24e-02	1.00e+00	6.324	1	1	9
GO:0035278	negative regulation of translation involved in gene silencing by miRNA	1.24e-02	1.00e+00	6.324	1	1	9
GO:0006983	ER overload response	1.24e-02	1.00e+00	6.324	1	1	9
GO:0043495	protein anchor	1.24e-02	1.00e+00	6.324	1	1	9
GO:0000400	four-way junction DNA binding	1.24e-02	1.00e+00	6.324	1	1	9
GO:0006241	CTP biosynthetic process	1.24e-02	1.00e+00	6.324	1	1	9
GO:0043296	apical junction complex	1.24e-02	1.00e+00	6.324	1	1	9
GO:0060071	Wnt signaling pathway, planar cell polarity pathway	1.38e-02	1.00e+00	6.172	1	1	10
GO:0090307	spindle assembly involved in mitosis	1.38e-02	1.00e+00	6.172	1	1	10
GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	1.38e-02	1.00e+00	6.172	1	2	10
GO:0035413	positive regulation of catenin import into nucleus	1.38e-02	1.00e+00	6.172	1	2	10
GO:0003700	sequence-specific DNA binding transcription factor activity	1.42e-02	1.00e+00	2.045	4	39	699
GO:0045662	negative regulation of myoblast differentiation	1.52e-02	1.00e+00	6.035	1	3	11
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	1.52e-02	1.00e+00	6.035	1	2	11
GO:0060391	positive regulation of SMAD protein import into nucleus	1.52e-02	1.00e+00	6.035	1	4	11
GO:0006878	cellular copper ion homeostasis	1.65e-02	1.00e+00	5.909	1	1	12
GO:0006402	mRNA catabolic process	1.65e-02	1.00e+00	5.909	1	1	12
GO:0045947	negative regulation of translational initiation	1.65e-02	1.00e+00	5.909	1	2	12
GO:0070935	3'-UTR-mediated mRNA stabilization	1.65e-02	1.00e+00	5.909	1	3	12
GO:0034399	nuclear periphery	1.65e-02	1.00e+00	5.909	1	5	12
GO:0005838	proteasome regulatory particle	1.65e-02	1.00e+00	5.909	1	1	12
GO:0035198	miRNA binding	1.65e-02	1.00e+00	5.909	1	1	12
GO:0071480	cellular response to gamma radiation	1.79e-02	1.00e+00	5.794	1	1	13
GO:0046688	response to copper ion	1.79e-02	1.00e+00	5.794	1	1	13
GO:0006165	nucleoside diphosphate phosphorylation	1.79e-02	1.00e+00	5.794	1	1	13
GO:0051019	mitogen-activated protein kinase binding	1.79e-02	1.00e+00	5.794	1	2	13
GO:0005868	cytoplasmic dynein complex	1.79e-02	1.00e+00	5.794	1	1	13
GO:0030234	enzyme regulator activity	1.79e-02	1.00e+00	5.794	1	2	13
GO:0046827	positive regulation of protein export from nucleus	1.79e-02	1.00e+00	5.794	1	1	13
GO:0010744	positive regulation of macrophage derived foam cell differentiation	1.92e-02	1.00e+00	5.687	1	1	14
GO:0001967	suckling behavior	1.92e-02	1.00e+00	5.687	1	1	14
GO:0004550	nucleoside diphosphate kinase activity	1.92e-02	1.00e+00	5.687	1	1	14
GO:0005685	U1 snRNP	1.92e-02	1.00e+00	5.687	1	1	14
GO:0031293	membrane protein intracellular domain proteolysis	1.92e-02	1.00e+00	5.687	1	1	14
GO:0017091	AU-rich element binding	1.92e-02	1.00e+00	5.687	1	2	14
GO:0071375	cellular response to peptide hormone stimulus	1.92e-02	1.00e+00	5.687	1	2	14
GO:0005487	nucleocytoplasmic transporter activity	1.92e-02	1.00e+00	5.687	1	3	14
GO:0043066	negative regulation of apoptotic process	1.98e-02	1.00e+00	2.351	3	16	424
GO:0042307	positive regulation of protein import into nucleus	2.06e-02	1.00e+00	5.587	1	4	15
GO:0001824	blastocyst development	2.06e-02	1.00e+00	5.587	1	2	15
GO:0006376	mRNA splice site selection	2.06e-02	1.00e+00	5.587	1	1	15
GO:0042176	regulation of protein catabolic process	2.20e-02	1.00e+00	5.494	1	2	16
GO:0001190	RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription	2.20e-02	1.00e+00	5.494	1	2	16
GO:0051276	chromosome organization	2.20e-02	1.00e+00	5.494	1	2	16
GO:0045638	negative regulation of myeloid cell differentiation	2.20e-02	1.00e+00	5.494	1	1	16
GO:0048593	camera-type eye morphogenesis	2.20e-02	1.00e+00	5.494	1	1	16
GO:0031965	nuclear membrane	2.23e-02	1.00e+00	3.102	2	10	168
GO:0050919	negative chemotaxis	2.33e-02	1.00e+00	5.407	1	1	17
GO:0017022	myosin binding	2.33e-02	1.00e+00	5.407	1	2	17
GO:0012506	vesicle membrane	2.33e-02	1.00e+00	5.407	1	1	17
GO:0090316	positive regulation of intracellular protein transport	2.33e-02	1.00e+00	5.407	1	2	17
GO:0022624	proteasome accessory complex	2.33e-02	1.00e+00	5.407	1	1	17
GO:0005667	transcription factor complex	2.41e-02	1.00e+00	3.043	2	17	175
GO:0050772	positive regulation of axonogenesis	2.47e-02	1.00e+00	5.324	1	1	18
GO:0071889	14-3-3 protein binding	2.47e-02	1.00e+00	5.324	1	2	18
GO:0042346	positive regulation of NF-kappaB import into nucleus	2.47e-02	1.00e+00	5.324	1	1	18
GO:0050771	negative regulation of axonogenesis	2.74e-02	1.00e+00	5.172	1	1	20
GO:0032757	positive regulation of interleukin-8 production	2.74e-02	1.00e+00	5.172	1	1	20
GO:0014003	oligodendrocyte development	2.74e-02	1.00e+00	5.172	1	5	20
GO:0043393	regulation of protein binding	2.74e-02	1.00e+00	5.172	1	1	20
GO:0045862	positive regulation of proteolysis	2.87e-02	1.00e+00	5.102	1	2	21
GO:0030864	cortical actin cytoskeleton	3.14e-02	1.00e+00	4.971	1	1	23
GO:0016573	histone acetylation	3.14e-02	1.00e+00	4.971	1	2	23
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	3.14e-02	1.00e+00	4.971	1	1	23
GO:1902017	regulation of cilium assembly	3.28e-02	1.00e+00	4.909	1	2	24
GO:0006611	protein export from nucleus	3.41e-02	1.00e+00	4.850	1	3	25
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	3.41e-02	1.00e+00	4.850	1	3	25
GO:0031519	PcG protein complex	3.41e-02	1.00e+00	4.850	1	1	25
GO:0051059	NF-kappaB binding	3.41e-02	1.00e+00	4.850	1	3	25
GO:0035329	hippo signaling	3.55e-02	1.00e+00	4.794	1	5	26
GO:0000976	transcription regulatory region sequence-specific DNA binding	3.55e-02	1.00e+00	4.794	1	3	26
GO:0051209	release of sequestered calcium ion into cytosol	3.55e-02	1.00e+00	4.794	1	1	26
GO:0050770	regulation of axonogenesis	3.55e-02	1.00e+00	4.794	1	2	26
GO:0016032	viral process	3.60e-02	1.00e+00	2.018	3	26	534
GO:0015631	tubulin binding	3.68e-02	1.00e+00	4.739	1	2	27
GO:0032467	positive regulation of cytokinesis	3.68e-02	1.00e+00	4.739	1	2	27
GO:0016071	mRNA metabolic process	3.77e-02	1.00e+00	2.693	2	8	223
GO:0003727	single-stranded RNA binding	3.81e-02	1.00e+00	4.687	1	2	28
GO:0034605	cellular response to heat	3.81e-02	1.00e+00	4.687	1	1	28
GO:0030901	midbrain development	3.95e-02	1.00e+00	4.636	1	1	29
GO:0072686	mitotic spindle	3.95e-02	1.00e+00	4.636	1	3	29
GO:0006606	protein import into nucleus	4.08e-02	1.00e+00	4.587	1	2	30
GO:0031647	regulation of protein stability	4.08e-02	1.00e+00	4.587	1	4	30
GO:0010827	regulation of glucose transport	4.08e-02	1.00e+00	4.587	1	4	30
GO:0034644	cellular response to UV	4.08e-02	1.00e+00	4.587	1	1	30
GO:0005544	calcium-dependent phospholipid binding	4.08e-02	1.00e+00	4.587	1	1	30
GO:0010494	cytoplasmic stress granule	4.08e-02	1.00e+00	4.587	1	2	30
GO:0007094	mitotic spindle assembly checkpoint	4.21e-02	1.00e+00	4.540	1	3	31
GO:0071347	cellular response to interleukin-1	4.21e-02	1.00e+00	4.540	1	2	31
GO:1903507	negative regulation of nucleic acid-templated transcription	4.35e-02	1.00e+00	4.494	1	2	32
GO:0005829	cytosol	4.44e-02	1.00e+00	1.016	7	86	2496
GO:0016070	RNA metabolic process	4.53e-02	1.00e+00	2.546	2	8	247
GO:0005097	Rab GTPase activator activity	4.61e-02	1.00e+00	4.407	1	1	34
GO:0030178	negative regulation of Wnt signaling pathway	4.75e-02	1.00e+00	4.365	1	4	35
GO:0007077	mitotic nuclear envelope disassembly	4.88e-02	1.00e+00	4.324	1	4	36
GO:0005902	microvillus	5.14e-02	1.00e+00	4.246	1	3	38
GO:0051496	positive regulation of stress fiber assembly	5.14e-02	1.00e+00	4.246	1	4	38
GO:0032154	cleavage furrow	5.14e-02	1.00e+00	4.246	1	1	38
GO:0003779	actin binding	5.18e-02	1.00e+00	2.439	2	10	266
GO:0008645	hexose transport	5.27e-02	1.00e+00	4.209	1	4	39
GO:0048011	neurotrophin TRK receptor signaling pathway	5.28e-02	1.00e+00	2.423	2	7	269
GO:0044822	poly(A) RNA binding	5.40e-02	1.00e+00	1.450	4	50	1056
GO:0035019	somatic stem cell maintenance	5.41e-02	1.00e+00	4.172	1	6	40
GO:0050885	neuromuscular process controlling balance	5.41e-02	1.00e+00	4.172	1	2	40
GO:0042147	retrograde transport, endosome to Golgi	5.54e-02	1.00e+00	4.137	1	1	41
GO:0006954	inflammatory response	5.56e-02	1.00e+00	2.380	2	6	277
GO:0019898	extrinsic component of membrane	5.67e-02	1.00e+00	4.102	1	2	42
GO:0006892	post-Golgi vesicle-mediated transport	5.80e-02	1.00e+00	4.068	1	2	43
GO:0004402	histone acetyltransferase activity	5.80e-02	1.00e+00	4.068	1	6	43
GO:0021762	substantia nigra development	5.93e-02	1.00e+00	4.035	1	4	44
GO:0043525	positive regulation of neuron apoptotic process	6.19e-02	1.00e+00	3.971	1	4	46
GO:0007266	Rho protein signal transduction	6.32e-02	1.00e+00	3.940	1	1	47
GO:0090263	positive regulation of canonical Wnt signaling pathway	6.45e-02	1.00e+00	3.909	1	3	48
GO:0000902	cell morphogenesis	6.58e-02	1.00e+00	3.879	1	4	49
GO:0030900	forebrain development	6.58e-02	1.00e+00	3.879	1	1	49
GO:0006521	regulation of cellular amino acid metabolic process	6.71e-02	1.00e+00	3.850	1	1	50
GO:0006986	response to unfolded protein	6.71e-02	1.00e+00	3.850	1	4	50
GO:0030334	regulation of cell migration	6.71e-02	1.00e+00	3.850	1	5	50
GO:0005525	GTP binding	6.79e-02	1.00e+00	2.218	2	12	310
GO:0034976	response to endoplasmic reticulum stress	6.84e-02	1.00e+00	3.822	1	2	51
GO:0045454	cell redox homeostasis	6.84e-02	1.00e+00	3.822	1	1	51
GO:0009611	response to wounding	6.97e-02	1.00e+00	3.794	1	5	52
GO:0032851	positive regulation of Rab GTPase activity	7.10e-02	1.00e+00	3.766	1	2	53
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	7.10e-02	1.00e+00	3.766	1	5	53
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	7.10e-02	1.00e+00	3.766	1	4	53
GO:0015758	glucose transport	7.36e-02	1.00e+00	3.713	1	4	55
GO:0000724	double-strand break repair via homologous recombination	7.36e-02	1.00e+00	3.713	1	2	55
GO:0003682	chromatin binding	7.45e-02	1.00e+00	2.141	2	19	327
GO:0016020	membrane	7.47e-02	1.00e+00	1.101	5	46	1681
GO:0051291	protein heterooligomerization	7.49e-02	1.00e+00	3.687	1	4	56
GO:0048306	calcium-dependent protein binding	7.49e-02	1.00e+00	3.687	1	2	56
GO:0036064	ciliary basal body	7.62e-02	1.00e+00	3.661	1	2	57
GO:0008203	cholesterol metabolic process	7.62e-02	1.00e+00	3.661	1	2	57
GO:0005643	nuclear pore	7.62e-02	1.00e+00	3.661	1	11	57
GO:0000502	proteasome complex	7.75e-02	1.00e+00	3.636	1	3	58
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	7.88e-02	1.00e+00	3.612	1	6	59
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	7.88e-02	1.00e+00	3.612	1	5	59
GO:0008013	beta-catenin binding	8.00e-02	1.00e+00	3.587	1	9	60
GO:0030855	epithelial cell differentiation	8.13e-02	1.00e+00	3.563	1	1	61
GO:0006987	activation of signaling protein activity involved in unfolded protein response	8.13e-02	1.00e+00	3.563	1	2	61
GO:0032481	positive regulation of type I interferon production	8.13e-02	1.00e+00	3.563	1	6	61
GO:0043565	sequence-specific DNA binding	8.21e-02	1.00e+00	2.060	2	11	346
GO:0032088	negative regulation of NF-kappaB transcription factor activity	8.39e-02	1.00e+00	3.517	1	3	63
GO:0004867	serine-type endopeptidase inhibitor activity	8.39e-02	1.00e+00	3.517	1	3	63
GO:0000776	kinetochore	8.39e-02	1.00e+00	3.517	1	5	63
GO:0045666	positive regulation of neuron differentiation	8.39e-02	1.00e+00	3.517	1	3	63
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	8.52e-02	1.00e+00	3.494	1	1	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	8.64e-02	1.00e+00	3.472	1	2	65
GO:0006310	DNA recombination	8.64e-02	1.00e+00	3.472	1	7	65
GO:0071260	cellular response to mechanical stimulus	8.64e-02	1.00e+00	3.472	1	4	65
GO:0034166	toll-like receptor 10 signaling pathway	8.64e-02	1.00e+00	3.472	1	4	65
GO:0034146	toll-like receptor 5 signaling pathway	8.64e-02	1.00e+00	3.472	1	4	65
GO:0010468	regulation of gene expression	9.02e-02	1.00e+00	3.407	1	2	68
GO:0005925	focal adhesion	9.04e-02	1.00e+00	1.978	2	9	366
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	9.28e-02	1.00e+00	3.365	1	2	70
GO:0005085	guanyl-nucleotide exchange factor activity	9.40e-02	1.00e+00	3.344	1	5	71
GO:0038123	toll-like receptor TLR1:TLR2 signaling pathway	9.40e-02	1.00e+00	3.344	1	4	71
GO:0007626	locomotory behavior	9.40e-02	1.00e+00	3.344	1	2	71
GO:0038124	toll-like receptor TLR6:TLR2 signaling pathway	9.40e-02	1.00e+00	3.344	1	4	71
GO:0043086	negative regulation of catalytic activity	9.53e-02	1.00e+00	3.324	1	2	72
GO:0034162	toll-like receptor 9 signaling pathway	9.53e-02	1.00e+00	3.324	1	4	72
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	9.53e-02	1.00e+00	3.324	1	1	72
GO:0034134	toll-like receptor 2 signaling pathway	9.66e-02	1.00e+00	3.304	1	4	73
GO:0002020	protease binding	9.78e-02	1.00e+00	3.285	1	6	74
GO:0001843	neural tube closure	9.78e-02	1.00e+00	3.285	1	2	74
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	9.78e-02	1.00e+00	3.285	1	4	74
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	9.78e-02	1.00e+00	3.285	1	2	74
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	9.91e-02	1.00e+00	3.265	1	1	75
GO:0060070	canonical Wnt signaling pathway	9.91e-02	1.00e+00	3.265	1	4	75
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	9.91e-02	1.00e+00	3.265	1	1	75
GO:0035666	TRIF-dependent toll-like receptor signaling pathway	1.00e-01	1.00e+00	3.246	1	3	76
GO:0000278	mitotic cell cycle	1.01e-01	1.00e+00	1.883	2	15	391
GO:0070062	extracellular vesicular exosome	1.01e-01	1.00e+00	0.850	6	57	2400
GO:0002756	MyD88-independent toll-like receptor signaling pathway	1.03e-01	1.00e+00	3.209	1	3	78
GO:0034138	toll-like receptor 3 signaling pathway	1.04e-01	1.00e+00	3.190	1	3	79
GO:0030968	endoplasmic reticulum unfolded protein response	1.04e-01	1.00e+00	3.190	1	2	79
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.04e-01	1.00e+00	3.190	1	2	79
GO:0005814	centriole	1.04e-01	1.00e+00	3.190	1	2	79
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	1.05e-01	1.00e+00	3.172	1	5	80
GO:0071222	cellular response to lipopolysaccharide	1.07e-01	1.00e+00	3.154	1	4	81
GO:0009653	anatomical structure morphogenesis	1.09e-01	1.00e+00	3.119	1	2	83
GO:0009952	anterior/posterior pattern specification	1.09e-01	1.00e+00	3.119	1	4	83
GO:0050852	T cell receptor signaling pathway	1.12e-01	1.00e+00	3.085	1	2	85
GO:0003690	double-stranded DNA binding	1.13e-01	1.00e+00	3.068	1	3	86
GO:0090090	negative regulation of canonical Wnt signaling pathway	1.13e-01	1.00e+00	3.068	1	8	86
GO:0006979	response to oxidative stress	1.14e-01	1.00e+00	3.051	1	6	87
GO:0016363	nuclear matrix	1.19e-01	1.00e+00	2.986	1	6	91
GO:0007010	cytoskeleton organization	1.19e-01	1.00e+00	2.986	1	4	91
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.20e-01	1.00e+00	2.971	1	1	92
GO:0051082	unfolded protein binding	1.21e-01	1.00e+00	2.955	1	7	93
GO:0005770	late endosome	1.21e-01	1.00e+00	2.955	1	2	93
GO:0030165	PDZ domain binding	1.23e-01	1.00e+00	2.940	1	1	94
GO:0034142	toll-like receptor 4 signaling pathway	1.25e-01	1.00e+00	2.909	1	4	96
GO:0005096	GTPase activator activity	1.32e-01	1.00e+00	2.822	1	2	102
GO:0005886	plasma membrane	1.33e-01	1.00e+00	0.745	6	49	2582
GO:0031410	cytoplasmic vesicle	1.34e-01	1.00e+00	2.808	1	4	103
GO:0010951	negative regulation of endopeptidase activity	1.35e-01	1.00e+00	2.794	1	6	104
GO:0005938	cell cortex	1.35e-01	1.00e+00	2.794	1	5	104
GO:0030496	midbody	1.40e-01	1.00e+00	2.739	1	2	108
GO:0002224	toll-like receptor signaling pathway	1.41e-01	1.00e+00	2.726	1	4	109
GO:0042802	identical protein binding	1.44e-01	1.00e+00	1.575	2	19	484
GO:0005635	nuclear envelope	1.46e-01	1.00e+00	2.674	1	5	113
GO:0048015	phosphatidylinositol-mediated signaling	1.47e-01	1.00e+00	2.661	1	2	114
GO:0051056	regulation of small GTPase mediated signal transduction	1.48e-01	1.00e+00	2.649	1	3	115
GO:0000209	protein polyubiquitination	1.49e-01	1.00e+00	2.636	1	3	116
GO:0008201	heparin binding	1.56e-01	1.00e+00	2.563	1	1	122
GO:0030036	actin cytoskeleton organization	1.58e-01	1.00e+00	2.552	1	3	123
GO:0051092	positive regulation of NF-kappaB transcription factor activity	1.59e-01	1.00e+00	2.540	1	5	124
GO:0007050	cell cycle arrest	1.59e-01	1.00e+00	2.540	1	5	124
GO:0030027	lamellipodium	1.60e-01	1.00e+00	2.528	1	7	125
GO:0007179	transforming growth factor beta receptor signaling pathway	1.63e-01	1.00e+00	2.494	1	11	128
GO:0005215	transporter activity	1.66e-01	1.00e+00	2.472	1	3	130
GO:0016055	Wnt signaling pathway	1.75e-01	1.00e+00	2.386	1	4	138
GO:0007507	heart development	1.76e-01	1.00e+00	2.375	1	7	139
GO:0006915	apoptotic process	1.79e-01	1.00e+00	1.378	2	12	555
GO:0006457	protein folding	1.81e-01	1.00e+00	2.334	1	7	143
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	1.83e-01	1.00e+00	2.314	1	4	145
GO:0000082	G1/S transition of mitotic cell cycle	1.88e-01	1.00e+00	2.275	1	3	149
GO:0042981	regulation of apoptotic process	1.89e-01	1.00e+00	2.265	1	4	150
GO:0007601	visual perception	1.97e-01	1.00e+00	2.200	1	5	157
GO:0042803	protein homodimerization activity	1.99e-01	1.00e+00	1.277	2	19	595
GO:0008022	protein C-terminus binding	2.01e-01	1.00e+00	2.163	1	8	161
GO:0038095	Fc-epsilon receptor signaling pathway	2.09e-01	1.00e+00	2.102	1	5	168
GO:0034641	cellular nitrogen compound metabolic process	2.12e-01	1.00e+00	2.076	1	2	171
GO:0016607	nuclear speck	2.13e-01	1.00e+00	2.068	1	12	172
GO:0031625	ubiquitin protein ligase binding	2.20e-01	1.00e+00	2.018	1	5	178
GO:0019904	protein domain specific binding	2.21e-01	1.00e+00	2.010	1	8	179
GO:0043547	positive regulation of GTPase activity	2.22e-01	1.00e+00	2.002	1	9	180
GO:0003924	GTPase activity	2.41e-01	1.00e+00	1.872	1	7	197
GO:0030168	platelet activation	2.49e-01	1.00e+00	1.815	1	6	205
GO:0005737	cytoplasm	2.51e-01	1.00e+00	0.422	7	124	3767
GO:0006184	GTP catabolic process	2.59e-01	1.00e+00	1.753	1	7	214
GO:0019221	cytokine-mediated signaling pathway	2.66e-01	1.00e+00	1.706	1	8	221
GO:0007067	mitotic nuclear division	2.72e-01	1.00e+00	1.668	1	6	227
GO:0008380	RNA splicing	2.73e-01	1.00e+00	1.661	1	22	228
GO:0005975	carbohydrate metabolic process	2.98e-01	1.00e+00	1.511	1	8	253
GO:0006281	DNA repair	3.06e-01	1.00e+00	1.466	1	14	261
GO:0007283	spermatogenesis	3.07e-01	1.00e+00	1.461	1	3	262
GO:0007264	small GTPase mediated signal transduction	3.24e-01	1.00e+00	1.370	1	3	279
GO:0030198	extracellular matrix organization	3.27e-01	1.00e+00	1.349	1	6	283
GO:0007186	G-protein coupled receptor signaling pathway	3.33e-01	1.00e+00	1.319	1	1	289
GO:0005856	cytoskeleton	3.35e-01	1.00e+00	1.309	1	9	291
GO:0030154	cell differentiation	3.44e-01	1.00e+00	1.261	1	5	301
GO:0035556	intracellular signal transduction	3.46e-01	1.00e+00	1.251	1	9	303
GO:0019901	protein kinase binding	3.59e-01	1.00e+00	1.186	1	18	317
GO:0007411	axon guidance	3.61e-01	1.00e+00	1.177	1	5	319
GO:0008283	cell proliferation	3.69e-01	1.00e+00	1.137	1	14	328
GO:0030054	cell junction	3.76e-01	1.00e+00	1.102	1	5	336
GO:0015031	protein transport	3.81e-01	1.00e+00	1.081	1	11	341
GO:0003723	RNA binding	3.81e-01	1.00e+00	1.076	1	18	342
GO:0005730	nucleolus	4.02e-01	1.00e+00	0.399	3	66	1641
GO:0046982	protein heterodimerization activity	4.14e-01	1.00e+00	0.924	1	8	380
GO:0009986	cell surface	4.32e-01	1.00e+00	0.843	1	9	402
GO:0045892	negative regulation of transcription, DNA-templated	4.41e-01	1.00e+00	0.804	1	24	413
GO:0055085	transmembrane transport	4.58e-01	1.00e+00	0.729	1	8	435
GO:0007596	blood coagulation	4.74e-01	1.00e+00	0.664	1	11	455
GO:0044267	cellular protein metabolic process	4.88e-01	1.00e+00	0.605	1	20	474
GO:0048471	perinuclear region of cytoplasm	5.08e-01	1.00e+00	0.523	1	8	502
GO:0044281	small molecule metabolic process	5.10e-01	1.00e+00	0.252	2	20	1211
GO:0005509	calcium ion binding	5.28e-01	1.00e+00	0.442	1	11	531
GO:0045087	innate immune response	5.70e-01	1.00e+00	0.275	1	15	596
GO:0005794	Golgi apparatus	5.79e-01	1.00e+00	0.241	1	9	610
GO:0006351	transcription, DNA-templated	6.10e-01	1.00e+00	-0.004	2	57	1446
GO:0007165	signal transduction	7.27e-01	1.00e+00	-0.331	1	13	907
GO:0008270	zinc ion binding	7.62e-01	1.00e+00	-0.467	1	27	997
GO:0005739	mitochondrion	7.62e-01	1.00e+00	-0.469	1	23	998
GO:0005524	ATP binding	8.49e-01	1.00e+00	-0.848	1	31	1298
GO:0046872	metal ion binding	8.51e-01	1.00e+00	-0.858	1	29	1307
GO:0016021	integral component of membrane	9.48e-01	1.00e+00	-1.459	1	17	1982

chia-Fav

int-snw-6102

Statistics

Genes (20)

Interactions (26)

Related GO terms (373)