int-snw-4825

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.847	1.25e-15	4.21e-04	3.07e-03

chia-screen-data-Fav-int-snw-4825 subnetwork

Genes (13)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
[ NKX6-1 ]	4825	1	-1.343	2.847	13	-	-
EP300	2033	22	-2.274	3.120	415	Yes	Yes
MCRS1	10445	14	-2.660	3.079	63	Yes	Yes
ZFP36	7538	10	-2.968	2.869	24	Yes	Yes
NFKB1	4790	9	-2.123	2.870	263	Yes	-
YAP1	10413	94	-4.256	3.538	53	Yes	-
TAF7	6879	3	-2.176	2.899	38	Yes	Yes
INO80E	283899	10	-2.663	3.079	20	Yes	-
NFRKB	4798	48	-3.129	3.108	23	Yes	Yes
YY1	7528	24	-2.572	3.120	114	Yes	Yes
HNRNPU	3192	76	-2.869	3.538	139	Yes	-
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
DDIT3	1649	60	-2.825	3.504	343	Yes	Yes

Interactions (21)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
YY1	7528	INO80E	283899	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid
NFRKB	4798	MCRS1	10445	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid
EP300	2033	HNRNPU	3192	pp	--	int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vitro, in vivo
NFRKB	4798	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
HNRNPU	3192	YAP1	10413	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
NFRKB	4798	YY1	7528	pp	--	int.I2D: BioGrid
TAF7	6879	YY1	7528	pp	--	int.Transfac: -
EP300	2033	YY1	7528	pp	--	int.I2D: BioGrid, BCI, HPRD; int.Transfac: -; int.Ravasi: -; int.HPRD: in vivo; int.DIP: MI:0218(physical interaction)
EP300	2033	NFKB1	4790	pp	--	int.I2D: BioGrid
MCRS1	10445	INO80E	283899	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct
NFKB1	4790	YY1	7528	pp	--	int.Intact: MI:0915(physical association)
NFKB1	4790	ZFP36	7538	pp	--	int.I2D: BioGrid
DDIT3	1649	NFKB1	4790	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
HNRNPU	3192	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
EP300	2033	YAP1	10413	pp	--	int.I2D: BioGrid
NFRKB	4798	INO80E	283899	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid
YY1	7528	MCRS1	10445	pp	--	int.I2D: BioGrid
DDIT3	1649	HNRNPU	3192	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
NKX6-1	4825	YY1	7528	pp	--	int.Yu: peripheral_nervous_system
NFKB1	4790	NFRKB	4798	pp	--	int.I2D: BCI, HPRD; int.Ravasi: -; int.HPRD: in vitro
DDIT3	1649	EP300	2033	pp	--	int.Intact: MI:0915(physical association)

Related GO terms (308)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0031011	Ino80 complex	3.95e-10	5.70e-06	8.308	4	6	14
GO:0044212	transcription regulatory region DNA binding	3.66e-09	5.28e-05	5.308	6	17	168
GO:0005634	nucleus	3.11e-07	4.48e-03	1.662	13	159	4559
GO:0008134	transcription factor binding	1.47e-06	2.12e-02	4.519	5	18	242
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	5.02e-06	7.24e-02	3.546	6	37	570
GO:0006355	regulation of transcription, DNA-templated	8.76e-06	1.26e-01	2.962	7	43	997
GO:0005654	nucleoplasm	1.51e-05	2.17e-01	2.844	7	64	1082
GO:0003700	sequence-specific DNA binding transcription factor activity	1.62e-05	2.34e-01	3.251	6	39	699
GO:0006366	transcription from RNA polymerase II promoter	2.14e-05	3.09e-01	3.727	5	30	419
GO:0006310	DNA recombination	2.42e-05	3.49e-01	5.678	3	7	65
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.24e-05	4.67e-01	3.077	6	41	789
GO:0003677	DNA binding	3.28e-05	4.73e-01	2.673	7	49	1218
GO:0003713	transcription coactivator activity	4.52e-05	6.52e-01	4.227	4	24	237
GO:0042789	mRNA transcription from RNA polymerase II promoter	5.82e-05	8.39e-01	7.415	2	2	13
GO:0071375	cellular response to peptide hormone stimulus	6.78e-05	9.78e-01	7.308	2	2	14
GO:0000123	histone acetyltransferase complex	1.56e-04	1.00e+00	6.723	2	6	21
GO:0005730	nucleolus	2.24e-04	1.00e+00	2.243	7	66	1641
GO:0005515	protein binding	2.24e-04	1.00e+00	1.144	12	198	6024
GO:0071339	MLL1 complex	2.60e-04	1.00e+00	6.361	2	6	27
GO:0006974	cellular response to DNA damage stimulus	2.98e-04	1.00e+00	4.462	3	7	151
GO:0042594	response to starvation	3.44e-04	1.00e+00	6.161	2	4	31
GO:0005667	transcription factor complex	4.59e-04	1.00e+00	4.249	3	17	175
GO:0003714	transcription corepressor activity	4.83e-04	1.00e+00	4.225	3	11	178
GO:2000016	negative regulation of determination of dorsal identity	9.01e-04	1.00e+00	10.116	1	1	1
GO:1901985	positive regulation of protein acetylation	9.01e-04	1.00e+00	10.116	1	1	1
GO:0043969	histone H2B acetylation	9.01e-04	1.00e+00	10.116	1	1	1
GO:0045083	negative regulation of interleukin-12 biosynthetic process	9.01e-04	1.00e+00	10.116	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	9.01e-04	1.00e+00	10.116	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	9.01e-04	1.00e+00	10.116	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	9.01e-04	1.00e+00	10.116	1	1	1
GO:0060795	cell fate commitment involved in formation of primary germ layer	9.01e-04	1.00e+00	10.116	1	1	1
GO:0060177	regulation of angiotensin metabolic process	9.01e-04	1.00e+00	10.116	1	1	1
GO:2000629	negative regulation of miRNA metabolic process	9.01e-04	1.00e+00	10.116	1	1	1
GO:0000296	spermine transport	9.01e-04	1.00e+00	10.116	1	1	1
GO:0050728	negative regulation of inflammatory response	1.12e-03	1.00e+00	5.308	2	3	56
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	1.25e-03	1.00e+00	5.233	2	5	59
GO:0032481	positive regulation of type I interferon production	1.33e-03	1.00e+00	5.185	2	6	61
GO:0006281	DNA repair	1.46e-03	1.00e+00	3.673	3	14	261
GO:0072560	type B pancreatic cell maturation	1.80e-03	1.00e+00	9.116	1	1	2
GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification	1.80e-03	1.00e+00	9.116	1	1	2
GO:0060242	contact inhibition	1.80e-03	1.00e+00	9.116	1	1	2
GO:0006403	RNA localization	1.80e-03	1.00e+00	9.116	1	1	2
GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification	1.80e-03	1.00e+00	9.116	1	1	2
GO:0009786	regulation of asymmetric cell division	1.80e-03	1.00e+00	9.116	1	1	2
GO:0090043	regulation of tubulin deacetylation	1.80e-03	1.00e+00	9.116	1	2	2
GO:0071389	cellular response to mineralocorticoid stimulus	1.80e-03	1.00e+00	9.116	1	1	2
GO:0045686	negative regulation of glial cell differentiation	1.80e-03	1.00e+00	9.116	1	1	2
GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	1.80e-03	1.00e+00	9.116	1	1	2
GO:0034696	response to prostaglandin F	1.80e-03	1.00e+00	9.116	1	1	2
GO:0014737	positive regulation of muscle atrophy	1.80e-03	1.00e+00	9.116	1	1	2
GO:0045687	positive regulation of glial cell differentiation	1.80e-03	1.00e+00	9.116	1	1	2
GO:0035984	cellular response to trichostatin A	1.80e-03	1.00e+00	9.116	1	1	2
GO:0044324	regulation of transcription involved in anterior/posterior axis specification	1.80e-03	1.00e+00	9.116	1	1	2
GO:0009887	organ morphogenesis	2.63e-03	1.00e+00	4.689	2	5	86
GO:0051594	detection of glucose	2.70e-03	1.00e+00	8.531	1	1	3
GO:2000078	positive regulation of type B pancreatic cell development	2.70e-03	1.00e+00	8.531	1	1	3
GO:0018076	N-terminal peptidyl-lysine acetylation	2.70e-03	1.00e+00	8.531	1	1	3
GO:0060913	cardiac cell fate determination	2.70e-03	1.00e+00	8.531	1	1	3
GO:1900127	positive regulation of hyaluronan biosynthetic process	2.70e-03	1.00e+00	8.531	1	1	3
GO:0050779	RNA destabilization	2.70e-03	1.00e+00	8.531	1	1	3
GO:0010560	positive regulation of glycoprotein biosynthetic process	2.70e-03	1.00e+00	8.531	1	1	3
GO:0010956	negative regulation of calcidiol 1-monooxygenase activity	2.70e-03	1.00e+00	8.531	1	1	3
GO:0033256	I-kappaB/NF-kappaB complex	2.70e-03	1.00e+00	8.531	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	2.70e-03	1.00e+00	8.531	1	1	3
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	3.00e-03	1.00e+00	4.592	2	7	92
GO:0032680	regulation of tumor necrosis factor production	3.60e-03	1.00e+00	8.116	1	1	4
GO:0032375	negative regulation of cholesterol transport	3.60e-03	1.00e+00	8.116	1	1	4
GO:0097157	pre-mRNA intronic binding	3.60e-03	1.00e+00	8.116	1	1	4
GO:0018393	internal peptidyl-lysine acetylation	3.60e-03	1.00e+00	8.116	1	1	4
GO:0010957	negative regulation of vitamin D biosynthetic process	3.60e-03	1.00e+00	8.116	1	1	4
GO:0032269	negative regulation of cellular protein metabolic process	3.60e-03	1.00e+00	8.116	1	1	4
GO:2000630	positive regulation of miRNA metabolic process	3.60e-03	1.00e+00	8.116	1	1	4
GO:0001714	endodermal cell fate specification	4.50e-03	1.00e+00	7.794	1	1	5
GO:0008024	positive transcription elongation factor complex b	4.50e-03	1.00e+00	7.794	1	1	5
GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	4.50e-03	1.00e+00	7.794	1	1	5
GO:0019957	C-C chemokine binding	4.50e-03	1.00e+00	7.794	1	1	5
GO:0043620	regulation of DNA-templated transcription in response to stress	4.50e-03	1.00e+00	7.794	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	4.50e-03	1.00e+00	7.794	1	2	5
GO:0010884	positive regulation of lipid storage	4.50e-03	1.00e+00	7.794	1	1	5
GO:0035925	mRNA 3'-UTR AU-rich region binding	4.50e-03	1.00e+00	7.794	1	1	5
GO:0065004	protein-DNA complex assembly	4.50e-03	1.00e+00	7.794	1	1	5
GO:0030516	regulation of axon extension	4.50e-03	1.00e+00	7.794	1	1	5
GO:0060298	positive regulation of sarcomere organization	4.50e-03	1.00e+00	7.794	1	1	5
GO:0032025	response to cobalt ion	4.50e-03	1.00e+00	7.794	1	1	5
GO:0006325	chromatin organization	4.88e-03	1.00e+00	4.233	2	12	118
GO:0070937	CRD-mediated mRNA stability complex	5.40e-03	1.00e+00	7.531	1	3	6
GO:0071354	cellular response to interleukin-6	6.29e-03	1.00e+00	7.308	1	2	7
GO:0006475	internal protein amino acid acetylation	6.29e-03	1.00e+00	7.308	1	1	7
GO:0001955	blood vessel maturation	7.19e-03	1.00e+00	7.116	1	1	8
GO:0071316	cellular response to nicotine	7.19e-03	1.00e+00	7.116	1	1	8
GO:0035067	negative regulation of histone acetylation	7.19e-03	1.00e+00	7.116	1	2	8
GO:2001222	regulation of neuron migration	7.19e-03	1.00e+00	7.116	1	1	8
GO:0035259	glucocorticoid receptor binding	8.09e-03	1.00e+00	6.946	1	1	9
GO:0000975	regulatory region DNA binding	8.09e-03	1.00e+00	6.946	1	2	9
GO:0045793	positive regulation of cell size	8.09e-03	1.00e+00	6.946	1	2	9
GO:0043996	histone acetyltransferase activity (H4-K8 specific)	8.09e-03	1.00e+00	6.946	1	5	9
GO:0043995	histone acetyltransferase activity (H4-K5 specific)	8.09e-03	1.00e+00	6.946	1	5	9
GO:0046972	histone acetyltransferase activity (H4-K16 specific)	8.09e-03	1.00e+00	6.946	1	5	9
GO:0060765	regulation of androgen receptor signaling pathway	8.09e-03	1.00e+00	6.946	1	1	9
GO:0010225	response to UV-C	8.09e-03	1.00e+00	6.946	1	2	9
GO:0035278	negative regulation of translation involved in gene silencing by miRNA	8.09e-03	1.00e+00	6.946	1	1	9
GO:0006983	ER overload response	8.09e-03	1.00e+00	6.946	1	1	9
GO:0000400	four-way junction DNA binding	8.09e-03	1.00e+00	6.946	1	1	9
GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	8.98e-03	1.00e+00	6.794	1	2	10
GO:0035413	positive regulation of catenin import into nucleus	8.98e-03	1.00e+00	6.794	1	2	10
GO:0016407	acetyltransferase activity	8.98e-03	1.00e+00	6.794	1	2	10
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	9.34e-03	1.00e+00	3.749	2	12	165
GO:0045662	negative regulation of myoblast differentiation	9.87e-03	1.00e+00	6.656	1	3	11
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	9.87e-03	1.00e+00	6.656	1	2	11
GO:0043923	positive regulation by host of viral transcription	9.87e-03	1.00e+00	6.656	1	1	11
GO:0033160	positive regulation of protein import into nucleus, translocation	9.87e-03	1.00e+00	6.656	1	3	11
GO:0042975	peroxisome proliferator activated receptor binding	9.87e-03	1.00e+00	6.656	1	1	11
GO:0060391	positive regulation of SMAD protein import into nucleus	9.87e-03	1.00e+00	6.656	1	4	11
GO:0006402	mRNA catabolic process	1.08e-02	1.00e+00	6.531	1	1	12
GO:0070935	3'-UTR-mediated mRNA stabilization	1.08e-02	1.00e+00	6.531	1	3	12
GO:0035198	miRNA binding	1.08e-02	1.00e+00	6.531	1	1	12
GO:0006367	transcription initiation from RNA polymerase II promoter	1.15e-02	1.00e+00	3.592	2	22	184
GO:0071480	cellular response to gamma radiation	1.17e-02	1.00e+00	6.415	1	1	13
GO:0016746	transferase activity, transferring acyl groups	1.17e-02	1.00e+00	6.415	1	1	13
GO:0046688	response to copper ion	1.17e-02	1.00e+00	6.415	1	1	13
GO:0051019	mitogen-activated protein kinase binding	1.17e-02	1.00e+00	6.415	1	2	13
GO:0010744	positive regulation of macrophage derived foam cell differentiation	1.26e-02	1.00e+00	6.308	1	1	14
GO:0033276	transcription factor TFTC complex	1.26e-02	1.00e+00	6.308	1	4	14
GO:0031293	membrane protein intracellular domain proteolysis	1.26e-02	1.00e+00	6.308	1	1	14
GO:0017091	AU-rich element binding	1.26e-02	1.00e+00	6.308	1	2	14
GO:0070542	response to fatty acid	1.26e-02	1.00e+00	6.308	1	1	14
GO:0032993	protein-DNA complex	1.26e-02	1.00e+00	6.308	1	2	14
GO:0042809	vitamin D receptor binding	1.34e-02	1.00e+00	6.209	1	6	15
GO:0043981	histone H4-K5 acetylation	1.34e-02	1.00e+00	6.209	1	5	15
GO:0001824	blastocyst development	1.34e-02	1.00e+00	6.209	1	2	15
GO:0043982	histone H4-K8 acetylation	1.34e-02	1.00e+00	6.209	1	5	15
GO:1990090	cellular response to nerve growth factor stimulus	1.34e-02	1.00e+00	6.209	1	1	15
GO:0071345	cellular response to cytokine stimulus	1.43e-02	1.00e+00	6.116	1	1	16
GO:0051276	chromosome organization	1.43e-02	1.00e+00	6.116	1	2	16
GO:0045638	negative regulation of myeloid cell differentiation	1.43e-02	1.00e+00	6.116	1	1	16
GO:0048593	camera-type eye morphogenesis	1.43e-02	1.00e+00	6.116	1	1	16
GO:0071889	14-3-3 protein binding	1.61e-02	1.00e+00	5.946	1	2	18
GO:0030520	intracellular estrogen receptor signaling pathway	1.61e-02	1.00e+00	5.946	1	4	18
GO:0045773	positive regulation of axon extension	1.61e-02	1.00e+00	5.946	1	1	18
GO:0033613	activating transcription factor binding	1.61e-02	1.00e+00	5.946	1	3	18
GO:0035035	histone acetyltransferase binding	1.70e-02	1.00e+00	5.868	1	1	19
GO:0043984	histone H4-K16 acetylation	1.70e-02	1.00e+00	5.868	1	5	19
GO:0035257	nuclear hormone receptor binding	1.70e-02	1.00e+00	5.868	1	1	19
GO:0071549	cellular response to dexamethasone stimulus	1.79e-02	1.00e+00	5.794	1	3	20
GO:0010942	positive regulation of cell death	1.79e-02	1.00e+00	5.794	1	1	20
GO:0032757	positive regulation of interleukin-8 production	1.79e-02	1.00e+00	5.794	1	1	20
GO:0006352	DNA-templated transcription, initiation	1.79e-02	1.00e+00	5.794	1	2	20
GO:0032967	positive regulation of collagen biosynthetic process	1.88e-02	1.00e+00	5.723	1	3	21
GO:0045862	positive regulation of proteolysis	1.88e-02	1.00e+00	5.723	1	2	21
GO:0031016	pancreas development	1.88e-02	1.00e+00	5.723	1	1	21
GO:0003823	antigen binding	1.97e-02	1.00e+00	5.656	1	2	22
GO:0005669	transcription factor TFIID complex	1.97e-02	1.00e+00	5.656	1	4	22
GO:0036464	cytoplasmic ribonucleoprotein granule	1.97e-02	1.00e+00	5.656	1	2	22
GO:0010467	gene expression	2.01e-02	1.00e+00	2.315	3	45	669
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	2.05e-02	1.00e+00	5.592	1	1	23
GO:0048709	oligodendrocyte differentiation	2.05e-02	1.00e+00	5.592	1	2	23
GO:0043388	positive regulation of DNA binding	2.14e-02	1.00e+00	5.531	1	2	24
GO:0043425	bHLH transcription factor binding	2.14e-02	1.00e+00	5.531	1	1	24
GO:0035094	response to nicotine	2.23e-02	1.00e+00	5.472	1	2	25
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	2.23e-02	1.00e+00	5.472	1	3	25
GO:0031519	PcG protein complex	2.23e-02	1.00e+00	5.472	1	1	25
GO:0051059	NF-kappaB binding	2.23e-02	1.00e+00	5.472	1	3	25
GO:0035329	hippo signaling	2.32e-02	1.00e+00	5.415	1	5	26
GO:0000976	transcription regulatory region sequence-specific DNA binding	2.32e-02	1.00e+00	5.415	1	3	26
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	2.32e-02	1.00e+00	5.415	1	1	26
GO:0051209	release of sequestered calcium ion into cytosol	2.32e-02	1.00e+00	5.415	1	1	26
GO:0048565	digestive tract development	2.32e-02	1.00e+00	5.415	1	2	26
GO:0046966	thyroid hormone receptor binding	2.32e-02	1.00e+00	5.415	1	6	26
GO:0034612	response to tumor necrosis factor	2.41e-02	1.00e+00	5.361	1	2	27
GO:0043967	histone H4 acetylation	2.41e-02	1.00e+00	5.361	1	1	27
GO:0006954	inflammatory response	2.49e-02	1.00e+00	3.002	2	6	277
GO:0003727	single-stranded RNA binding	2.50e-02	1.00e+00	5.308	1	2	28
GO:0050714	positive regulation of protein secretion	2.50e-02	1.00e+00	5.308	1	3	28
GO:0034644	cellular response to UV	2.67e-02	1.00e+00	5.209	1	1	30
GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	2.67e-02	1.00e+00	5.209	1	1	30
GO:0010494	cytoplasmic stress granule	2.67e-02	1.00e+00	5.209	1	2	30
GO:0071347	cellular response to interleukin-1	2.76e-02	1.00e+00	5.161	1	2	31
GO:0043491	protein kinase B signaling	2.85e-02	1.00e+00	5.116	1	2	32
GO:1903507	negative regulation of nucleic acid-templated transcription	2.85e-02	1.00e+00	5.116	1	2	32
GO:0001756	somitogenesis	2.94e-02	1.00e+00	5.071	1	1	33
GO:0032024	positive regulation of insulin secretion	2.94e-02	1.00e+00	5.071	1	3	33
GO:0071333	cellular response to glucose stimulus	2.94e-02	1.00e+00	5.071	1	1	33
GO:0031072	heat shock protein binding	2.94e-02	1.00e+00	5.071	1	2	33
GO:0031018	endocrine pancreas development	3.11e-02	1.00e+00	4.986	1	2	35
GO:0001102	RNA polymerase II activating transcription factor binding	3.20e-02	1.00e+00	4.946	1	1	36
GO:0031490	chromatin DNA binding	3.37e-02	1.00e+00	4.868	1	2	38
GO:0032092	positive regulation of protein binding	3.37e-02	1.00e+00	4.868	1	2	38
GO:0050681	androgen receptor binding	3.37e-02	1.00e+00	4.868	1	1	38
GO:0003682	chromatin binding	3.39e-02	1.00e+00	2.762	2	19	327
GO:0008283	cell proliferation	3.41e-02	1.00e+00	2.758	2	14	328
GO:0006351	transcription, DNA-templated	3.44e-02	1.00e+00	1.618	4	57	1446
GO:0046332	SMAD binding	3.55e-02	1.00e+00	4.794	1	2	40
GO:0071320	cellular response to cAMP	3.55e-02	1.00e+00	4.794	1	1	40
GO:0035019	somatic stem cell maintenance	3.55e-02	1.00e+00	4.794	1	6	40
GO:0007519	skeletal muscle tissue development	3.55e-02	1.00e+00	4.794	1	2	40
GO:0070301	cellular response to hydrogen peroxide	3.63e-02	1.00e+00	4.758	1	2	41
GO:0003723	RNA binding	3.68e-02	1.00e+00	2.698	2	18	342
GO:0043565	sequence-specific DNA binding	3.76e-02	1.00e+00	2.681	2	11	346
GO:0004402	histone acetyltransferase activity	3.81e-02	1.00e+00	4.689	1	6	43
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3.90e-02	1.00e+00	4.656	1	4	44
GO:0045727	positive regulation of translation	3.90e-02	1.00e+00	4.656	1	2	44
GO:0043966	histone H3 acetylation	3.98e-02	1.00e+00	4.624	1	5	45
GO:0001047	core promoter binding	3.98e-02	1.00e+00	4.624	1	5	45
GO:0043525	positive regulation of neuron apoptotic process	4.07e-02	1.00e+00	4.592	1	4	46
GO:0090263	positive regulation of canonical Wnt signaling pathway	4.24e-02	1.00e+00	4.531	1	3	48
GO:0007224	smoothened signaling pathway	4.24e-02	1.00e+00	4.531	1	1	48
GO:0035690	cellular response to drug	4.33e-02	1.00e+00	4.501	1	3	49
GO:0006986	response to unfolded protein	4.42e-02	1.00e+00	4.472	1	4	50
GO:0034976	response to endoplasmic reticulum stress	4.50e-02	1.00e+00	4.443	1	2	51
GO:0045454	cell redox homeostasis	4.50e-02	1.00e+00	4.443	1	1	51
GO:0009611	response to wounding	4.59e-02	1.00e+00	4.415	1	5	52
GO:0007623	circadian rhythm	4.68e-02	1.00e+00	4.388	1	1	53
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	4.68e-02	1.00e+00	4.388	1	4	53
GO:0051592	response to calcium ion	4.85e-02	1.00e+00	4.334	1	1	55
GO:0002039	p53 binding	4.85e-02	1.00e+00	4.334	1	4	55
GO:0071300	cellular response to retinoic acid	4.85e-02	1.00e+00	4.334	1	1	55
GO:0000724	double-strand break repair via homologous recombination	4.85e-02	1.00e+00	4.334	1	2	55
GO:0043627	response to estrogen	4.93e-02	1.00e+00	4.308	1	5	56
GO:0045892	negative regulation of transcription, DNA-templated	5.18e-02	1.00e+00	2.426	2	24	413
GO:0006396	RNA processing	5.19e-02	1.00e+00	4.233	1	5	59
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	5.19e-02	1.00e+00	4.233	1	6	59
GO:0008013	beta-catenin binding	5.28e-02	1.00e+00	4.209	1	9	60
GO:0006987	activation of signaling protein activity involved in unfolded protein response	5.36e-02	1.00e+00	4.185	1	2	61
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	5.53e-02	1.00e+00	4.138	1	4	63
GO:0045666	positive regulation of neuron differentiation	5.53e-02	1.00e+00	4.138	1	3	63
GO:0071260	cellular response to mechanical stimulus	5.71e-02	1.00e+00	4.093	1	4	65
GO:0034166	toll-like receptor 10 signaling pathway	5.71e-02	1.00e+00	4.093	1	4	65
GO:0006469	negative regulation of protein kinase activity	5.71e-02	1.00e+00	4.093	1	4	65
GO:0034146	toll-like receptor 5 signaling pathway	5.71e-02	1.00e+00	4.093	1	4	65
GO:0005829	cytosol	5.88e-02	1.00e+00	1.152	5	86	2496
GO:0010468	regulation of gene expression	5.96e-02	1.00e+00	4.028	1	2	68
GO:0038123	toll-like receptor TLR1:TLR2 signaling pathway	6.22e-02	1.00e+00	3.966	1	4	71
GO:0038124	toll-like receptor TLR6:TLR2 signaling pathway	6.22e-02	1.00e+00	3.966	1	4	71
GO:0034162	toll-like receptor 9 signaling pathway	6.30e-02	1.00e+00	3.946	1	4	72
GO:0003729	mRNA binding	6.30e-02	1.00e+00	3.946	1	4	72
GO:0030324	lung development	6.30e-02	1.00e+00	3.946	1	1	72
GO:0034134	toll-like receptor 2 signaling pathway	6.39e-02	1.00e+00	3.926	1	4	73
GO:0000785	chromatin	6.39e-02	1.00e+00	3.926	1	6	73
GO:0044822	poly(A) RNA binding	6.44e-02	1.00e+00	1.656	3	50	1056
GO:0002020	protease binding	6.47e-02	1.00e+00	3.906	1	6	74
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	6.47e-02	1.00e+00	3.906	1	4	74
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	6.56e-02	1.00e+00	3.887	1	1	75
GO:0035666	TRIF-dependent toll-like receptor signaling pathway	6.64e-02	1.00e+00	3.868	1	3	76
GO:0001889	liver development	6.72e-02	1.00e+00	3.849	1	3	77
GO:0045893	positive regulation of transcription, DNA-templated	6.72e-02	1.00e+00	2.215	2	24	478
GO:0071013	catalytic step 2 spliceosome	6.81e-02	1.00e+00	3.830	1	7	78
GO:0002756	MyD88-independent toll-like receptor signaling pathway	6.81e-02	1.00e+00	3.830	1	3	78
GO:0034138	toll-like receptor 3 signaling pathway	6.89e-02	1.00e+00	3.812	1	3	79
GO:0030968	endoplasmic reticulum unfolded protein response	6.89e-02	1.00e+00	3.812	1	2	79
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	6.98e-02	1.00e+00	3.794	1	5	80
GO:0071222	cellular response to lipopolysaccharide	7.06e-02	1.00e+00	3.776	1	4	81
GO:0009653	anatomical structure morphogenesis	7.23e-02	1.00e+00	3.741	1	2	83
GO:0009952	anterior/posterior pattern specification	7.23e-02	1.00e+00	3.741	1	4	83
GO:0006464	cellular protein modification process	7.32e-02	1.00e+00	3.723	1	4	84
GO:0050852	T cell receptor signaling pathway	7.40e-02	1.00e+00	3.706	1	2	85
GO:0003690	double-stranded DNA binding	7.48e-02	1.00e+00	3.689	1	3	86
GO:0090090	negative regulation of canonical Wnt signaling pathway	7.48e-02	1.00e+00	3.689	1	8	86
GO:0045471	response to ethanol	7.48e-02	1.00e+00	3.689	1	3	86
GO:0006979	response to oxidative stress	7.57e-02	1.00e+00	3.673	1	6	87
GO:0016363	nuclear matrix	7.90e-02	1.00e+00	3.608	1	6	91
GO:0001649	osteoblast differentiation	7.99e-02	1.00e+00	3.592	1	5	92
GO:0071456	cellular response to hypoxia	7.99e-02	1.00e+00	3.592	1	3	92
GO:0005770	late endosome	8.07e-02	1.00e+00	3.576	1	2	93
GO:0034142	toll-like receptor 4 signaling pathway	8.32e-02	1.00e+00	3.531	1	4	96
GO:0051726	regulation of cell cycle	8.40e-02	1.00e+00	3.516	1	5	97
GO:0006915	apoptotic process	8.71e-02	1.00e+00	1.999	2	12	555
GO:0001934	positive regulation of protein phosphorylation	8.98e-02	1.00e+00	3.415	1	5	104
GO:0002224	toll-like receptor signaling pathway	9.39e-02	1.00e+00	3.347	1	4	109
GO:0005737	cytoplasm	9.60e-02	1.00e+00	0.821	6	124	3767
GO:0030529	ribonucleoprotein complex	9.64e-02	1.00e+00	3.308	1	5	112
GO:0045087	innate immune response	9.84e-02	1.00e+00	1.896	2	15	596
GO:0007219	Notch signaling pathway	1.03e-01	1.00e+00	3.209	1	5	120
GO:0006260	DNA replication	1.04e-01	1.00e+00	3.197	1	3	121
GO:0051092	positive regulation of NF-kappaB transcription factor activity	1.06e-01	1.00e+00	3.161	1	5	124
GO:0007050	cell cycle arrest	1.06e-01	1.00e+00	3.161	1	5	124
GO:0000086	G2/M transition of mitotic cell cycle	1.16e-01	1.00e+00	3.028	1	4	136
GO:0016055	Wnt signaling pathway	1.18e-01	1.00e+00	3.007	1	4	138
GO:0007507	heart development	1.18e-01	1.00e+00	2.997	1	7	139
GO:0001666	response to hypoxia	1.26e-01	1.00e+00	2.896	1	7	149
GO:0000398	mRNA splicing, via spliceosome	1.38e-01	1.00e+00	2.758	1	15	164
GO:0038095	Fc-epsilon receptor signaling pathway	1.41e-01	1.00e+00	2.723	1	5	168
GO:0031625	ubiquitin protein ligase binding	1.49e-01	1.00e+00	2.640	1	5	178
GO:0032403	protein complex binding	1.53e-01	1.00e+00	2.600	1	6	183
GO:0016071	mRNA metabolic process	1.83e-01	1.00e+00	2.315	1	8	223
GO:0008380	RNA splicing	1.87e-01	1.00e+00	2.283	1	22	228
GO:0007399	nervous system development	1.89e-01	1.00e+00	2.264	1	6	231
GO:0016070	RNA metabolic process	2.01e-01	1.00e+00	2.167	1	8	247
GO:0007283	spermatogenesis	2.12e-01	1.00e+00	2.082	1	3	262
GO:0006357	regulation of transcription from RNA polymerase II promoter	2.14e-01	1.00e+00	2.071	1	23	264
GO:0048011	neurotrophin TRK receptor signaling pathway	2.17e-01	1.00e+00	2.044	1	7	269
GO:0008270	zinc ion binding	2.25e-01	1.00e+00	1.154	2	27	997
GO:0042493	response to drug	2.28e-01	1.00e+00	1.966	1	6	284
GO:0030154	cell differentiation	2.40e-01	1.00e+00	1.882	1	5	301
GO:0035556	intracellular signal transduction	2.41e-01	1.00e+00	1.872	1	9	303
GO:0019901	protein kinase binding	2.51e-01	1.00e+00	1.807	1	18	317
GO:0046982	protein heterodimerization activity	2.93e-01	1.00e+00	1.546	1	8	380
GO:0000278	mitotic cell cycle	3.01e-01	1.00e+00	1.505	1	15	391
GO:0009986	cell surface	3.08e-01	1.00e+00	1.465	1	9	402
GO:0043066	negative regulation of apoptotic process	3.22e-01	1.00e+00	1.388	1	16	424
GO:0044267	cellular protein metabolic process	3.52e-01	1.00e+00	1.227	1	20	474
GO:0016032	viral process	3.88e-01	1.00e+00	1.055	1	26	534
GO:0042803	protein homodimerization activity	4.22e-01	1.00e+00	0.899	1	19	595
GO:0005794	Golgi apparatus	4.30e-01	1.00e+00	0.863	1	9	610
GO:0005739	mitochondrion	6.06e-01	1.00e+00	0.153	1	23	998
GO:0005524	ATP binding	7.07e-01	1.00e+00	-0.226	1	31	1298
GO:0046872	metal ion binding	7.09e-01	1.00e+00	-0.236	1	29	1307
GO:0016020	membrane	8.00e-01	1.00e+00	-0.599	1	46	1681
GO:0070062	extracellular vesicular exosome	9.06e-01	1.00e+00	-1.113	1	57	2400

chia-Fav

int-snw-4825

Statistics

Genes (13)

Interactions (21)

Related GO terms (308)