int-snw-4670

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.857	9.71e-16	3.73e-04	2.82e-03

chia-screen-data-Fav-int-snw-4670 subnetwork

Genes (18)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
HCFC1	3054	40	-2.925	3.449	71	Yes	Yes
MED19	219541	30	-2.657	3.449	115	Yes	-
PXN	5829	19	-2.554	3.193	206	Yes	Yes
YAP1	10413	94	-4.256	3.538	53	Yes	-
APC	324	13	-2.293	3.004	353	Yes	-
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
ULK2	9706	9	-2.292	3.197	312	Yes	Yes
ZFP36	7538	10	-2.968	2.869	24	Yes	Yes
LUC7L3	51747	33	-3.523	3.449	18	Yes	-
NFKB1	4790	9	-2.123	2.870	263	Yes	-
SRSF3	6428	73	-2.992	3.538	54	Yes	-
NFRKB	4798	48	-3.129	3.108	23	Yes	Yes
MVP	9961	16	-2.846	3.193	20	Yes	Yes
HNRNPU	3192	76	-2.869	3.538	139	Yes	-
DDIT3	1649	60	-2.825	3.504	343	Yes	Yes
[ HNRNPM ]	4670	1	-1.884	2.857	117	-	-
STK4	6789	3	-2.048	3.110	228	Yes	-
MAP3K1	4214	3	-2.088	2.975	123	Yes	-

Interactions (29)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
SRSF3	6428	MED19	219541	pp	--	int.Intact: MI:0914(association); int.I2D: IntAct
HNRNPM	4670	PXN	5829	pp	--	int.I2D: BIND
PXN	5829	MVP	9961	pp	--	int.I2D: BIND
DDIT3	1649	NFKB1	4790	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
APC	324	HNRNPM	4670	pp	--	int.I2D: BioGrid, SOURAV_MAPK_HIGH
NFKB1	4790	ULK2	9706	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
HNRNPM	4670	MED19	219541	pp	--	int.Intact: MI:0914(association); int.I2D: IntAct
APC	324	PXN	5829	pp	--	int.I2D: MINT, MINT_Mouse; int.Mint: MI:0914(association)
NFRKB	4798	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
LUC7L3	51747	MED19	219541	pp	--	int.Intact: MI:0914(association); int.I2D: IntAct
NFKB1	4790	NFRKB	4798	pp	--	int.I2D: BCI, HPRD; int.Ravasi: -; int.HPRD: in vitro
PXN	5829	SRSF3	6428	pp	--	int.I2D: BIND
APC	324	NFKB1	4790	pp	--	int.I2D: IntAct, SOURAV_MAPK_LOW
HCFC1	3054	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
HNRNPM	4670	NFKB1	4790	pp	--	int.I2D: MINT; int.Mint: MI:0915(physical association)
POU5F1	5460	SRSF3	6428	pp	--	int.I2D: BioGrid
SRSF3	6428	ULK2	9706	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
HNRNPM	4670	STK4	6789	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
MAP3K1	4214	HNRNPM	4670	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, MINT; int.Mint: MI:0915(physical association)
HNRNPU	3192	ULK2	9706	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
HCFC1	3054	MED19	219541	pp	--	int.Intact: MI:0914(association); int.I2D: IntAct
HNRNPU	3192	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
HNRNPU	3192	YAP1	10413	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
HNRNPM	4670	ULK2	9706	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
SRSF3	6428	STK4	6789	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
HNRNPU	3192	STK4	6789	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
NFKB1	4790	ZFP36	7538	pp	--	int.I2D: BioGrid
DDIT3	1649	HNRNPU	3192	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
DDIT3	1649	HNRNPM	4670	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW

Related GO terms (339)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005515	protein binding	3.86e-06	5.56e-02	1.177	17	198	6024
GO:0042594	response to starvation	7.18e-06	1.04e-01	6.277	3	4	31
GO:0006366	transcription from RNA polymerase II promoter	8.00e-06	1.15e-01	3.520	6	30	419
GO:0005634	nucleus	8.84e-06	1.27e-01	1.399	15	159	4559
GO:0005654	nucleoplasm	2.17e-05	3.12e-01	2.567	8	64	1082
GO:0019901	protein kinase binding	3.37e-05	4.85e-01	3.660	5	18	317
GO:0044212	transcription regulatory region DNA binding	4.78e-05	6.90e-01	4.254	4	17	168
GO:0042789	mRNA transcription from RNA polymerase II promoter	1.14e-04	1.00e+00	6.946	2	2	13
GO:0008380	RNA splicing	1.56e-04	1.00e+00	3.813	4	22	228
GO:0090090	negative regulation of canonical Wnt signaling pathway	1.57e-04	1.00e+00	4.805	3	8	86
GO:0008134	transcription factor binding	1.97e-04	1.00e+00	3.727	4	18	242
GO:0035329	hippo signaling	4.70e-04	1.00e+00	5.946	2	5	26
GO:0006974	cellular response to DNA damage stimulus	8.18e-04	1.00e+00	3.993	3	7	151
GO:0000398	mRNA splicing, via spliceosome	1.04e-03	1.00e+00	3.874	3	15	164
GO:0010467	gene expression	1.09e-03	1.00e+00	2.582	5	45	669
GO:0035019	somatic stem cell maintenance	1.12e-03	1.00e+00	5.324	2	6	40
GO:2000016	negative regulation of determination of dorsal identity	1.25e-03	1.00e+00	9.646	1	1	1
GO:0023057	negative regulation of signaling	1.25e-03	1.00e+00	9.646	1	1	1
GO:0051435	BH4 domain binding	1.25e-03	1.00e+00	9.646	1	1	1
GO:0045083	negative regulation of interleukin-12 biosynthetic process	1.25e-03	1.00e+00	9.646	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	1.25e-03	1.00e+00	9.646	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	1.25e-03	1.00e+00	9.646	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	1.25e-03	1.00e+00	9.646	1	1	1
GO:0042483	negative regulation of odontogenesis	1.25e-03	1.00e+00	9.646	1	1	1
GO:0060795	cell fate commitment involved in formation of primary germ layer	1.25e-03	1.00e+00	9.646	1	1	1
GO:0051171	regulation of nitrogen compound metabolic process	1.25e-03	1.00e+00	9.646	1	1	1
GO:0072376	protein activation cascade	1.25e-03	1.00e+00	9.646	1	1	1
GO:0044822	poly(A) RNA binding	1.31e-03	1.00e+00	2.187	6	50	1056
GO:0005829	cytosol	1.48e-03	1.00e+00	1.531	9	86	2496
GO:0050728	negative regulation of inflammatory response	2.18e-03	1.00e+00	4.839	2	3	56
GO:0060242	contact inhibition	2.49e-03	1.00e+00	8.646	1	1	2
GO:0044337	canonical Wnt signaling pathway involved in positive regulation of apoptotic process	2.49e-03	1.00e+00	8.646	1	1	2
GO:0019046	release from viral latency	2.49e-03	1.00e+00	8.646	1	2	2
GO:0009786	regulation of asymmetric cell division	2.49e-03	1.00e+00	8.646	1	1	2
GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	2.49e-03	1.00e+00	8.646	1	1	2
GO:0008013	beta-catenin binding	2.49e-03	1.00e+00	4.739	2	9	60
GO:0009798	axis specification	2.49e-03	1.00e+00	8.646	1	1	2
GO:0044324	regulation of transcription involved in anterior/posterior axis specification	2.49e-03	1.00e+00	8.646	1	1	2
GO:0003677	DNA binding	2.74e-03	1.00e+00	1.981	6	49	1218
GO:0071260	cellular response to mechanical stimulus	2.92e-03	1.00e+00	4.624	2	4	65
GO:0034166	toll-like receptor 10 signaling pathway	2.92e-03	1.00e+00	4.624	2	4	65
GO:0034146	toll-like receptor 5 signaling pathway	2.92e-03	1.00e+00	4.624	2	4	65
GO:0038123	toll-like receptor TLR1:TLR2 signaling pathway	3.47e-03	1.00e+00	4.496	2	4	71
GO:0038124	toll-like receptor TLR6:TLR2 signaling pathway	3.47e-03	1.00e+00	4.496	2	4	71
GO:0034162	toll-like receptor 9 signaling pathway	3.57e-03	1.00e+00	4.476	2	4	72
GO:0003729	mRNA binding	3.57e-03	1.00e+00	4.476	2	4	72
GO:0034134	toll-like receptor 2 signaling pathway	3.67e-03	1.00e+00	4.456	2	4	73
GO:0060215	primitive hemopoiesis	3.74e-03	1.00e+00	8.061	1	1	3
GO:0008545	JUN kinase kinase activity	3.74e-03	1.00e+00	8.061	1	1	3
GO:0060913	cardiac cell fate determination	3.74e-03	1.00e+00	8.061	1	1	3
GO:1900127	positive regulation of hyaluronan biosynthetic process	3.74e-03	1.00e+00	8.061	1	1	3
GO:0050779	RNA destabilization	3.74e-03	1.00e+00	8.061	1	1	3
GO:0010956	negative regulation of calcidiol 1-monooxygenase activity	3.74e-03	1.00e+00	8.061	1	1	3
GO:0033256	I-kappaB/NF-kappaB complex	3.74e-03	1.00e+00	8.061	1	1	3
GO:0003157	endocardium development	3.74e-03	1.00e+00	8.061	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	3.74e-03	1.00e+00	8.061	1	1	3
GO:0071013	catalytic step 2 spliceosome	4.18e-03	1.00e+00	4.361	2	7	78
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	4.39e-03	1.00e+00	4.324	2	5	80
GO:0032680	regulation of tumor necrosis factor production	4.98e-03	1.00e+00	7.646	1	1	4
GO:0032375	negative regulation of cholesterol transport	4.98e-03	1.00e+00	7.646	1	1	4
GO:0034273	ATG1/UKL1 signaling complex	4.98e-03	1.00e+00	7.646	1	1	4
GO:0038127	ERBB signaling pathway	4.98e-03	1.00e+00	7.646	1	1	4
GO:0010957	negative regulation of vitamin D biosynthetic process	4.98e-03	1.00e+00	7.646	1	1	4
GO:0032269	negative regulation of cellular protein metabolic process	4.98e-03	1.00e+00	7.646	1	1	4
GO:2000630	positive regulation of miRNA metabolic process	4.98e-03	1.00e+00	7.646	1	1	4
GO:0019887	protein kinase regulator activity	4.98e-03	1.00e+00	7.646	1	1	4
GO:0070461	SAGA-type complex	6.23e-03	1.00e+00	7.324	1	2	5
GO:0001714	endodermal cell fate specification	6.23e-03	1.00e+00	7.324	1	1	5
GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process	6.23e-03	1.00e+00	7.324	1	2	5
GO:0019957	C-C chemokine binding	6.23e-03	1.00e+00	7.324	1	1	5
GO:0043620	regulation of DNA-templated transcription in response to stress	6.23e-03	1.00e+00	7.324	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	6.23e-03	1.00e+00	7.324	1	2	5
GO:0010884	positive regulation of lipid storage	6.23e-03	1.00e+00	7.324	1	1	5
GO:0035925	mRNA 3'-UTR AU-rich region binding	6.23e-03	1.00e+00	7.324	1	1	5
GO:0048671	negative regulation of collateral sprouting	6.23e-03	1.00e+00	7.324	1	1	5
GO:0034142	toll-like receptor 4 signaling pathway	6.26e-03	1.00e+00	4.061	2	4	96
GO:0006355	regulation of transcription, DNA-templated	6.27e-03	1.00e+00	2.007	5	43	997
GO:0030858	positive regulation of epithelial cell differentiation	7.47e-03	1.00e+00	7.061	1	1	6
GO:0060706	cell differentiation involved in embryonic placenta development	7.47e-03	1.00e+00	7.061	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	7.47e-03	1.00e+00	7.061	1	3	6
GO:0042382	paraspeckles	7.47e-03	1.00e+00	7.061	1	2	6
GO:0005737	cytoplasm	7.54e-03	1.00e+00	1.089	10	124	3767
GO:0002224	toll-like receptor signaling pathway	8.00e-03	1.00e+00	3.878	2	4	109
GO:0003723	RNA binding	8.28e-03	1.00e+00	2.813	3	18	342
GO:0030529	ribonucleoprotein complex	8.43e-03	1.00e+00	3.839	2	5	112
GO:0007091	metaphase/anaphase transition of mitotic cell cycle	8.71e-03	1.00e+00	6.839	1	2	7
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	8.71e-03	1.00e+00	6.839	1	1	7
GO:0071354	cellular response to interleukin-6	8.71e-03	1.00e+00	6.839	1	2	7
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	8.71e-03	1.00e+00	6.839	1	2	7
GO:0061099	negative regulation of protein tyrosine kinase activity	8.71e-03	1.00e+00	6.839	1	1	7
GO:0003700	sequence-specific DNA binding transcription factor activity	9.71e-03	1.00e+00	2.197	4	39	699
GO:0045670	regulation of osteoclast differentiation	9.94e-03	1.00e+00	6.646	1	2	8
GO:0001955	blood vessel maturation	9.94e-03	1.00e+00	6.646	1	1	8
GO:0071316	cellular response to nicotine	9.94e-03	1.00e+00	6.646	1	1	8
GO:0070688	MLL5-L complex	9.94e-03	1.00e+00	6.646	1	1	8
GO:0043254	regulation of protein complex assembly	9.94e-03	1.00e+00	6.646	1	1	8
GO:0007172	signal complex assembly	9.94e-03	1.00e+00	6.646	1	1	8
GO:0060396	growth hormone receptor signaling pathway	9.94e-03	1.00e+00	6.646	1	1	8
GO:0007050	cell cycle arrest	1.03e-02	1.00e+00	3.692	2	5	124
GO:0030027	lamellipodium	1.04e-02	1.00e+00	3.680	2	7	125
GO:0007179	transforming growth factor beta receptor signaling pathway	1.09e-02	1.00e+00	3.646	2	11	128
GO:0045667	regulation of osteoblast differentiation	1.12e-02	1.00e+00	6.476	1	1	9
GO:0031953	negative regulation of protein autophosphorylation	1.12e-02	1.00e+00	6.476	1	1	9
GO:0000975	regulatory region DNA binding	1.12e-02	1.00e+00	6.476	1	2	9
GO:0043996	histone acetyltransferase activity (H4-K8 specific)	1.12e-02	1.00e+00	6.476	1	5	9
GO:0043995	histone acetyltransferase activity (H4-K5 specific)	1.12e-02	1.00e+00	6.476	1	5	9
GO:0097284	hepatocyte apoptotic process	1.12e-02	1.00e+00	6.476	1	1	9
GO:0046972	histone acetyltransferase activity (H4-K16 specific)	1.12e-02	1.00e+00	6.476	1	5	9
GO:0035278	negative regulation of translation involved in gene silencing by miRNA	1.12e-02	1.00e+00	6.476	1	1	9
GO:0048188	Set1C/COMPASS complex	1.12e-02	1.00e+00	6.476	1	4	9
GO:0006983	ER overload response	1.12e-02	1.00e+00	6.476	1	1	9
GO:0003382	epithelial cell morphogenesis	1.12e-02	1.00e+00	6.476	1	1	9
GO:0005730	nucleolus	1.19e-02	1.00e+00	1.551	6	66	1641
GO:0031274	positive regulation of pseudopodium assembly	1.24e-02	1.00e+00	6.324	1	2	10
GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	1.24e-02	1.00e+00	6.324	1	2	10
GO:0035413	positive regulation of catenin import into nucleus	1.24e-02	1.00e+00	6.324	1	2	10
GO:0061029	eyelid development in camera-type eye	1.24e-02	1.00e+00	6.324	1	2	10
GO:0001841	neural tube formation	1.24e-02	1.00e+00	6.324	1	1	10
GO:0030877	beta-catenin destruction complex	1.24e-02	1.00e+00	6.324	1	2	10
GO:0051010	microtubule plus-end binding	1.36e-02	1.00e+00	6.187	1	1	11
GO:0045662	negative regulation of myoblast differentiation	1.36e-02	1.00e+00	6.187	1	3	11
GO:0017166	vinculin binding	1.36e-02	1.00e+00	6.187	1	1	11
GO:0000380	alternative mRNA splicing, via spliceosome	1.36e-02	1.00e+00	6.187	1	2	11
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	1.36e-02	1.00e+00	6.187	1	2	11
GO:0031116	positive regulation of microtubule polymerization	1.36e-02	1.00e+00	6.187	1	1	11
GO:0046621	negative regulation of organ growth	1.36e-02	1.00e+00	6.187	1	1	11
GO:0060391	positive regulation of SMAD protein import into nucleus	1.36e-02	1.00e+00	6.187	1	4	11
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	1.47e-02	1.00e+00	2.022	4	41	789
GO:0032886	regulation of microtubule-based process	1.49e-02	1.00e+00	6.061	1	1	12
GO:0006402	mRNA catabolic process	1.49e-02	1.00e+00	6.061	1	1	12
GO:0070935	3'-UTR-mediated mRNA stabilization	1.49e-02	1.00e+00	6.061	1	3	12
GO:0045295	gamma-catenin binding	1.49e-02	1.00e+00	6.061	1	1	12
GO:0034045	pre-autophagosomal structure membrane	1.49e-02	1.00e+00	6.061	1	2	12
GO:0035198	miRNA binding	1.49e-02	1.00e+00	6.061	1	1	12
GO:0071480	cellular response to gamma radiation	1.61e-02	1.00e+00	5.946	1	1	13
GO:0046688	response to copper ion	1.61e-02	1.00e+00	5.946	1	1	13
GO:0044295	axonal growth cone	1.61e-02	1.00e+00	5.946	1	1	13
GO:0043409	negative regulation of MAPK cascade	1.61e-02	1.00e+00	5.946	1	2	13
GO:0046777	protein autophosphorylation	1.63e-02	1.00e+00	3.342	2	4	158
GO:0010744	positive regulation of macrophage derived foam cell differentiation	1.73e-02	1.00e+00	5.839	1	1	14
GO:0035371	microtubule plus-end	1.73e-02	1.00e+00	5.839	1	1	14
GO:0005685	U1 snRNP	1.73e-02	1.00e+00	5.839	1	1	14
GO:0031011	Ino80 complex	1.73e-02	1.00e+00	5.839	1	6	14
GO:0031293	membrane protein intracellular domain proteolysis	1.73e-02	1.00e+00	5.839	1	1	14
GO:0017091	AU-rich element binding	1.73e-02	1.00e+00	5.839	1	2	14
GO:0034614	cellular response to reactive oxygen species	1.73e-02	1.00e+00	5.839	1	2	14
GO:0071375	cellular response to peptide hormone stimulus	1.73e-02	1.00e+00	5.839	1	2	14
GO:0043539	protein serine/threonine kinase activator activity	1.73e-02	1.00e+00	5.839	1	1	14
GO:0038095	Fc-epsilon receptor signaling pathway	1.83e-02	1.00e+00	3.254	2	5	168
GO:0043981	histone H4-K5 acetylation	1.86e-02	1.00e+00	5.739	1	5	15
GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex	1.86e-02	1.00e+00	5.739	1	3	15
GO:0001824	blastocyst development	1.86e-02	1.00e+00	5.739	1	2	15
GO:0043982	histone H4-K8 acetylation	1.86e-02	1.00e+00	5.739	1	5	15
GO:0006376	mRNA splice site selection	1.86e-02	1.00e+00	5.739	1	1	15
GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	1.86e-02	1.00e+00	5.739	1	1	15
GO:0016607	nuclear speck	1.91e-02	1.00e+00	3.220	2	12	172
GO:0007026	negative regulation of microtubule depolymerization	1.98e-02	1.00e+00	5.646	1	1	16
GO:0046716	muscle cell cellular homeostasis	1.98e-02	1.00e+00	5.646	1	1	16
GO:0043274	phospholipase binding	1.98e-02	1.00e+00	5.646	1	1	16
GO:0051276	chromosome organization	1.98e-02	1.00e+00	5.646	1	2	16
GO:0045638	negative regulation of myeloid cell differentiation	1.98e-02	1.00e+00	5.646	1	1	16
GO:0003714	transcription corepressor activity	2.04e-02	1.00e+00	3.170	2	11	178
GO:0071889	14-3-3 protein binding	2.22e-02	1.00e+00	5.476	1	2	18
GO:0031122	cytoplasmic microtubule organization	2.22e-02	1.00e+00	5.476	1	1	18
GO:0004709	MAP kinase kinase kinase activity	2.22e-02	1.00e+00	5.476	1	2	18
GO:0043984	histone H4-K16 acetylation	2.35e-02	1.00e+00	5.398	1	5	19
GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	2.35e-02	1.00e+00	5.398	1	2	19
GO:0032757	positive regulation of interleukin-8 production	2.47e-02	1.00e+00	5.324	1	1	20
GO:0048675	axon extension	2.59e-02	1.00e+00	5.254	1	2	21
GO:0048041	focal adhesion assembly	2.59e-02	1.00e+00	5.254	1	1	21
GO:0000123	histone acetyltransferase complex	2.59e-02	1.00e+00	5.254	1	6	21
GO:0009954	proximal/distal pattern formation	2.59e-02	1.00e+00	5.254	1	1	21
GO:0008637	apoptotic mitochondrial changes	2.59e-02	1.00e+00	5.254	1	2	21
GO:0000281	mitotic cytokinesis	2.59e-02	1.00e+00	5.254	1	2	21
GO:0045787	positive regulation of cell cycle	2.71e-02	1.00e+00	5.187	1	2	22
GO:0036464	cytoplasmic ribonucleoprotein granule	2.71e-02	1.00e+00	5.187	1	2	22
GO:0001205	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	2.71e-02	1.00e+00	5.187	1	4	22
GO:0010506	regulation of autophagy	2.83e-02	1.00e+00	5.123	1	2	23
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	2.83e-02	1.00e+00	5.123	1	1	23
GO:0045296	cadherin binding	2.95e-02	1.00e+00	5.061	1	3	24
GO:0006915	apoptotic process	3.01e-02	1.00e+00	2.115	3	12	555
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	3.08e-02	1.00e+00	5.002	1	3	25
GO:0000045	autophagic vacuole assembly	3.20e-02	1.00e+00	4.946	1	2	26
GO:0000976	transcription regulatory region sequence-specific DNA binding	3.20e-02	1.00e+00	4.946	1	3	26
GO:0071902	positive regulation of protein serine/threonine kinase activity	3.20e-02	1.00e+00	4.946	1	2	26
GO:0051209	release of sequestered calcium ion into cytosol	3.20e-02	1.00e+00	4.946	1	1	26
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.22e-02	1.00e+00	2.076	3	37	570
GO:0048754	branching morphogenesis of an epithelial tube	3.32e-02	1.00e+00	4.891	1	1	27
GO:0071339	MLL1 complex	3.32e-02	1.00e+00	4.891	1	6	27
GO:0005875	microtubule associated complex	3.44e-02	1.00e+00	4.839	1	1	28
GO:0003727	single-stranded RNA binding	3.44e-02	1.00e+00	4.839	1	2	28
GO:0070830	tight junction assembly	3.44e-02	1.00e+00	4.839	1	1	28
GO:0003713	transcription coactivator activity	3.46e-02	1.00e+00	2.757	2	24	237
GO:0005913	cell-cell adherens junction	3.56e-02	1.00e+00	4.788	1	3	29
GO:0030032	lamellipodium assembly	3.56e-02	1.00e+00	4.788	1	1	29
GO:0010494	cytoplasmic stress granule	3.68e-02	1.00e+00	4.739	1	2	30
GO:0009953	dorsal/ventral pattern formation	3.80e-02	1.00e+00	4.692	1	2	31
GO:0001569	patterning of blood vessels	3.80e-02	1.00e+00	4.692	1	1	31
GO:0007094	mitotic spindle assembly checkpoint	3.80e-02	1.00e+00	4.692	1	3	31
GO:0071347	cellular response to interleukin-1	3.80e-02	1.00e+00	4.692	1	2	31
GO:1903507	negative regulation of nucleic acid-templated transcription	3.92e-02	1.00e+00	4.646	1	2	32
GO:0045600	positive regulation of fat cell differentiation	3.92e-02	1.00e+00	4.646	1	2	32
GO:0033077	T cell differentiation in thymus	4.04e-02	1.00e+00	4.602	1	1	33
GO:0031072	heat shock protein binding	4.04e-02	1.00e+00	4.602	1	2	33
GO:0001104	RNA polymerase II transcription cofactor activity	4.04e-02	1.00e+00	4.602	1	8	33
GO:0000166	nucleotide binding	4.07e-02	1.00e+00	2.629	2	13	259
GO:0030838	positive regulation of actin filament polymerization	4.16e-02	1.00e+00	4.559	1	1	34
GO:0016592	mediator complex	4.28e-02	1.00e+00	4.517	1	10	35
GO:0001942	hair follicle development	4.28e-02	1.00e+00	4.517	1	2	35
GO:0043065	positive regulation of apoptotic process	4.33e-02	1.00e+00	2.580	2	7	268
GO:0007257	activation of JUN kinase activity	4.40e-02	1.00e+00	4.476	1	5	36
GO:0034446	substrate adhesion-dependent cell spreading	4.40e-02	1.00e+00	4.476	1	2	36
GO:0048538	thymus development	4.40e-02	1.00e+00	4.476	1	2	36
GO:0006954	inflammatory response	4.59e-02	1.00e+00	2.532	2	6	277
GO:0032092	positive regulation of protein binding	4.64e-02	1.00e+00	4.398	1	2	38
GO:0051781	positive regulation of cell division	4.76e-02	1.00e+00	4.361	1	1	39
GO:0005881	cytoplasmic microtubule	4.88e-02	1.00e+00	4.324	1	1	40
GO:0045785	positive regulation of cell adhesion	4.88e-02	1.00e+00	4.324	1	2	40
GO:0031124	mRNA 3'-end processing	5.12e-02	1.00e+00	4.254	1	2	42
GO:0035556	intracellular signal transduction	5.39e-02	1.00e+00	2.403	2	9	303
GO:0006369	termination of RNA polymerase II transcription	5.47e-02	1.00e+00	4.154	1	2	45
GO:0004674	protein serine/threonine kinase activity	5.55e-02	1.00e+00	2.379	2	6	308
GO:0016328	lateral plasma membrane	5.59e-02	1.00e+00	4.123	1	3	46
GO:0043525	positive regulation of neuron apoptotic process	5.59e-02	1.00e+00	4.123	1	4	46
GO:0006921	cellular component disassembly involved in execution phase of apoptosis	5.71e-02	1.00e+00	4.092	1	2	47
GO:0030216	keratinocyte differentiation	5.71e-02	1.00e+00	4.092	1	2	47
GO:0090263	positive regulation of canonical Wnt signaling pathway	5.83e-02	1.00e+00	4.061	1	3	48
GO:0000902	cell morphogenesis	5.95e-02	1.00e+00	4.031	1	4	49
GO:0006986	response to unfolded protein	6.06e-02	1.00e+00	4.002	1	4	50
GO:0030334	regulation of cell migration	6.06e-02	1.00e+00	4.002	1	5	50
GO:0045732	positive regulation of protein catabolic process	6.06e-02	1.00e+00	4.002	1	1	50
GO:0060041	retina development in camera-type eye	6.18e-02	1.00e+00	3.974	1	2	51
GO:0034976	response to endoplasmic reticulum stress	6.18e-02	1.00e+00	3.974	1	2	51
GO:0045454	cell redox homeostasis	6.18e-02	1.00e+00	3.974	1	1	51
GO:0008283	cell proliferation	6.21e-02	1.00e+00	2.289	2	14	328
GO:0051028	mRNA transport	6.30e-02	1.00e+00	3.946	1	4	52
GO:0009611	response to wounding	6.30e-02	1.00e+00	3.946	1	5	52
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	6.42e-02	1.00e+00	3.918	1	4	53
GO:0000186	activation of MAPKK activity	6.53e-02	1.00e+00	3.891	1	2	54
GO:0001725	stress fiber	6.65e-02	1.00e+00	3.865	1	4	55
GO:0043565	sequence-specific DNA binding	6.82e-02	1.00e+00	2.212	2	11	346
GO:0005643	nuclear pore	6.88e-02	1.00e+00	3.813	1	11	57
GO:0008285	negative regulation of cell proliferation	7.06e-02	1.00e+00	2.183	2	10	353
GO:0006396	RNA processing	7.12e-02	1.00e+00	3.764	1	5	59
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	7.12e-02	1.00e+00	3.764	1	6	59
GO:0005524	ATP binding	7.21e-02	1.00e+00	1.304	4	31	1298
GO:0006987	activation of signaling protein activity involved in unfolded protein response	7.35e-02	1.00e+00	3.715	1	2	61
GO:0032481	positive regulation of type I interferon production	7.35e-02	1.00e+00	3.715	1	6	61
GO:0006406	mRNA export from nucleus	7.35e-02	1.00e+00	3.715	1	4	61
GO:0019903	protein phosphatase binding	7.47e-02	1.00e+00	3.692	1	2	62
GO:0005925	focal adhesion	7.52e-02	1.00e+00	2.130	2	9	366
GO:0000776	kinetochore	7.58e-02	1.00e+00	3.669	1	5	63
GO:0007155	cell adhesion	7.63e-02	1.00e+00	2.119	2	5	369
GO:0042060	wound healing	7.70e-02	1.00e+00	3.646	1	2	64
GO:0006310	DNA recombination	7.81e-02	1.00e+00	3.624	1	7	65
GO:0007409	axonogenesis	7.81e-02	1.00e+00	3.624	1	2	65
GO:0010468	regulation of gene expression	8.16e-02	1.00e+00	3.559	1	2	68
GO:0034329	cell junction assembly	8.16e-02	1.00e+00	3.559	1	3	68
GO:0018105	peptidyl-serine phosphorylation	8.27e-02	1.00e+00	3.538	1	2	69
GO:0032587	ruffle membrane	8.39e-02	1.00e+00	3.517	1	3	70
GO:0002020	protease binding	8.85e-02	1.00e+00	3.437	1	6	74
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	8.85e-02	1.00e+00	3.437	1	4	74
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	8.96e-02	1.00e+00	3.417	1	1	75
GO:0060070	canonical Wnt signaling pathway	8.96e-02	1.00e+00	3.417	1	4	75
GO:0035666	TRIF-dependent toll-like receptor signaling pathway	9.08e-02	1.00e+00	3.398	1	3	76
GO:0001822	kidney development	9.30e-02	1.00e+00	3.361	1	3	78
GO:0007229	integrin-mediated signaling pathway	9.30e-02	1.00e+00	3.361	1	3	78
GO:0002756	MyD88-independent toll-like receptor signaling pathway	9.30e-02	1.00e+00	3.361	1	3	78
GO:0034138	toll-like receptor 3 signaling pathway	9.42e-02	1.00e+00	3.342	1	3	79
GO:0030968	endoplasmic reticulum unfolded protein response	9.42e-02	1.00e+00	3.342	1	2	79
GO:0071222	cellular response to lipopolysaccharide	9.65e-02	1.00e+00	3.306	1	4	81
GO:0009653	anatomical structure morphogenesis	9.87e-02	1.00e+00	3.271	1	2	83
GO:0009952	anterior/posterior pattern specification	9.87e-02	1.00e+00	3.271	1	4	83
GO:0005681	spliceosomal complex	9.87e-02	1.00e+00	3.271	1	3	83
GO:0007165	signal transduction	1.00e-01	1.00e+00	1.406	3	13	907
GO:0050852	T cell receptor signaling pathway	1.01e-01	1.00e+00	3.237	1	2	85
GO:0005923	tight junction	1.02e-01	1.00e+00	3.220	1	2	86
GO:0003690	double-stranded DNA binding	1.02e-01	1.00e+00	3.220	1	3	86
GO:0006979	response to oxidative stress	1.03e-01	1.00e+00	3.203	1	6	87
GO:0006936	muscle contraction	1.03e-01	1.00e+00	3.203	1	3	87
GO:0050821	protein stabilization	1.04e-01	1.00e+00	3.187	1	3	88
GO:0000187	activation of MAPK activity	1.07e-01	1.00e+00	3.154	1	3	90
GO:0016363	nuclear matrix	1.08e-01	1.00e+00	3.138	1	6	91
GO:0007010	cytoskeleton organization	1.08e-01	1.00e+00	3.138	1	4	91
GO:0006928	cellular component movement	1.08e-01	1.00e+00	3.138	1	3	91
GO:0001649	osteoblast differentiation	1.09e-01	1.00e+00	3.123	1	5	92
GO:0005770	late endosome	1.10e-01	1.00e+00	3.107	1	2	93
GO:0006468	protein phosphorylation	1.11e-01	1.00e+00	1.801	2	10	460
GO:0007417	central nervous system development	1.13e-01	1.00e+00	3.061	1	5	96
GO:0005178	integrin binding	1.13e-01	1.00e+00	3.061	1	4	96
GO:0045893	positive regulation of transcription, DNA-templated	1.18e-01	1.00e+00	1.745	2	24	478
GO:0030659	cytoplasmic vesicle membrane	1.19e-01	1.00e+00	2.988	1	2	101
GO:0008360	regulation of cell shape	1.21e-01	1.00e+00	2.960	1	4	103
GO:0042802	identical protein binding	1.21e-01	1.00e+00	1.727	2	19	484
GO:0005938	cell cortex	1.22e-01	1.00e+00	2.946	1	5	104
GO:0006461	protein complex assembly	1.30e-01	1.00e+00	2.852	1	4	111
GO:0046983	protein dimerization activity	1.38e-01	1.00e+00	2.764	1	5	118
GO:0006325	chromatin organization	1.38e-01	1.00e+00	2.764	1	12	118
GO:0051092	positive regulation of NF-kappaB transcription factor activity	1.44e-01	1.00e+00	2.692	1	5	124
GO:0030335	positive regulation of cell migration	1.47e-01	1.00e+00	2.657	1	5	127
GO:0016477	cell migration	1.48e-01	1.00e+00	2.646	1	4	128
GO:0016020	membrane	1.50e-01	1.00e+00	0.931	4	46	1681
GO:0018108	peptidyl-tyrosine phosphorylation	1.53e-01	1.00e+00	2.602	1	4	132
GO:0016055	Wnt signaling pathway	1.59e-01	1.00e+00	2.538	1	4	138
GO:0010628	positive regulation of gene expression	1.67e-01	1.00e+00	2.456	1	7	146
GO:0008017	microtubule binding	1.68e-01	1.00e+00	2.446	1	2	147
GO:0042803	protein homodimerization activity	1.69e-01	1.00e+00	1.429	2	19	595
GO:0045087	innate immune response	1.69e-01	1.00e+00	1.427	2	15	596
GO:0031012	extracellular matrix	1.76e-01	1.00e+00	2.379	1	6	154
GO:0000287	magnesium ion binding	1.86e-01	1.00e+00	2.289	1	4	164
GO:0007049	cell cycle	1.96e-01	1.00e+00	2.203	1	6	174
GO:0005667	transcription factor complex	1.97e-01	1.00e+00	2.195	1	17	175
GO:0004672	protein kinase activity	1.99e-01	1.00e+00	2.179	1	3	177
GO:0031625	ubiquitin protein ligase binding	2.00e-01	1.00e+00	2.170	1	5	178
GO:0019904	protein domain specific binding	2.01e-01	1.00e+00	2.162	1	8	179
GO:0006367	transcription initiation from RNA polymerase II promoter	2.06e-01	1.00e+00	2.123	1	22	184
GO:0007173	epidermal growth factor receptor signaling pathway	2.11e-01	1.00e+00	2.084	1	5	189
GO:0016071	mRNA metabolic process	2.45e-01	1.00e+00	1.845	1	8	223
GO:0043025	neuronal cell body	2.66e-01	1.00e+00	1.710	1	9	245
GO:0016070	RNA metabolic process	2.67e-01	1.00e+00	1.698	1	8	247
GO:0006281	DNA repair	2.80e-01	1.00e+00	1.618	1	14	261
GO:0006357	regulation of transcription from RNA polymerase II promoter	2.83e-01	1.00e+00	1.602	1	23	264
GO:0048011	neurotrophin TRK receptor signaling pathway	2.88e-01	1.00e+00	1.575	1	7	269
GO:0005856	cytoskeleton	3.07e-01	1.00e+00	1.461	1	9	291
GO:0005813	centrosome	3.38e-01	1.00e+00	1.297	1	7	326
GO:0003682	chromatin binding	3.38e-01	1.00e+00	1.293	1	19	327
GO:0015031	protein transport	3.50e-01	1.00e+00	1.233	1	11	341
GO:0008270	zinc ion binding	3.56e-01	1.00e+00	0.685	2	27	997
GO:0005739	mitochondrion	3.57e-01	1.00e+00	0.683	2	23	998
GO:0046982	protein heterodimerization activity	3.82e-01	1.00e+00	1.076	1	8	380
GO:0009986	cell surface	3.99e-01	1.00e+00	0.995	1	9	402
GO:0045892	negative regulation of transcription, DNA-templated	4.07e-01	1.00e+00	0.956	1	24	413
GO:0043066	negative regulation of apoptotic process	4.16e-01	1.00e+00	0.918	1	16	424
GO:0044267	cellular protein metabolic process	4.52e-01	1.00e+00	0.757	1	20	474
GO:0048471	perinuclear region of cytoplasm	4.72e-01	1.00e+00	0.675	1	8	502
GO:0005886	plasma membrane	6.50e-01	1.00e+00	-0.103	3	49	2582
GO:0005887	integral component of plasma membrane	6.82e-01	1.00e+00	-0.148	1	10	888
GO:0046872	metal ion binding	8.19e-01	1.00e+00	-0.706	1	29	1307
GO:0070062	extracellular vesicular exosome	8.27e-01	1.00e+00	-0.583	2	57	2400

chia-Fav

int-snw-4670

Statistics

Genes (18)

Interactions (29)

Related GO terms (339)