int-snw-4435
Statistics
| Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
|---|---|---|---|---|
| chia-screen-data-Fav | 2.867 | 7.44e-16 | 3.27e-04 | 2.57e-03 |
Genes (15)
| Gene Symbol | Entrez Gene ID | Frequency | chia-screen-data-Fav gene score | Best subnetwork score | Degree | Chia-Hits Primary | Chia-Hits Secondary |
|---|---|---|---|---|---|---|---|
| EP300 | 2033 | 22 | -2.274 | 3.120 | 415 | Yes | Yes |
| TPR | 7175 | 18 | -2.638 | 3.072 | 28 | Yes | Yes |
| APLP2 | 334 | 12 | -2.732 | 3.206 | 35 | Yes | Yes |
| [ CITED1 ] | 4435 | 1 | -1.982 | 2.867 | 15 | - | - |
| ANXA4 | 307 | 7 | -2.478 | 3.062 | 15 | Yes | Yes |
| ZFP36 | 7538 | 10 | -2.968 | 2.869 | 24 | Yes | Yes |
| NFKB1 | 4790 | 9 | -2.123 | 2.870 | 263 | Yes | - |
| YAP1 | 10413 | 94 | -4.256 | 3.538 | 53 | Yes | - |
| HES6 | 55502 | 8 | -2.557 | 3.120 | 11 | Yes | Yes |
| TCL1A | 8115 | 8 | -2.457 | 3.120 | 11 | Yes | Yes |
| NFRKB | 4798 | 48 | -3.129 | 3.108 | 23 | Yes | Yes |
| YY1 | 7528 | 24 | -2.572 | 3.120 | 114 | Yes | Yes |
| HNRNPU | 3192 | 76 | -2.869 | 3.538 | 139 | Yes | - |
| POU5F1 | 5460 | 133 | -5.148 | 3.538 | 179 | Yes | Yes |
| DDIT3 | 1649 | 60 | -2.825 | 3.504 | 343 | Yes | Yes |
Interactions (21)
| Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
|---|---|---|---|---|---|---|
| NFRKB | 4798 | YY1 | 7528 | pp | -- | int.I2D: BioGrid |
| NFKB1 | 4790 | ZFP36 | 7538 | pp | -- | int.I2D: BioGrid |
| DDIT3 | 1649 | NFKB1 | 4790 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
| APLP2 | 334 | NFKB1 | 4790 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
| HNRNPU | 3192 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
| EP300 | 2033 | HES6 | 55502 | pp | -- | int.I2D: IntAct |
| DDIT3 | 1649 | EP300 | 2033 | pp | -- | int.Intact: MI:0915(physical association) |
| NFKB1 | 4790 | TPR | 7175 | pp | -- | int.I2D: MINT; int.Mint: MI:0915(physical association) |
| CITED1 | 4435 | NFKB1 | 4790 | pp | -- | int.Ravasi: - |
| EP300 | 2033 | HNRNPU | 3192 | pp | -- | int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vitro, in vivo |
| NFRKB | 4798 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
| HNRNPU | 3192 | YAP1 | 10413 | pp | -- | int.I2D: HPRD; int.HPRD: in vitro, in vivo |
| EP300 | 2033 | YY1 | 7528 | pp | -- | int.I2D: BioGrid, BCI, HPRD; int.Transfac: -; int.Ravasi: -; int.HPRD: in vivo; int.DIP: MI:0218(physical interaction) |
| EP300 | 2033 | NFKB1 | 4790 | pp | -- | int.I2D: BioGrid |
| NFKB1 | 4790 | YY1 | 7528 | pp | -- | int.Intact: MI:0915(physical association) |
| EP300 | 2033 | TCL1A | 8115 | pp | -- | int.I2D: INNATEDB |
| EP300 | 2033 | CITED1 | 4435 | pp | -- | int.I2D: BioGrid, HPRD; int.Ravasi: -; int.HPRD: in vitro, in vivo |
| ANXA4 | 307 | NFKB1 | 4790 | pp | -- | int.I2D: BioGrid, INNATEDB |
| EP300 | 2033 | YAP1 | 10413 | pp | -- | int.I2D: BioGrid |
| DDIT3 | 1649 | HNRNPU | 3192 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
| NFKB1 | 4790 | NFRKB | 4798 | pp | -- | int.I2D: BCI, HPRD; int.Ravasi: -; int.HPRD: in vitro |
Related GO terms (393)
| Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
|---|---|---|---|---|---|---|---|
| GO:0044212 | transcription regulatory region DNA binding | 1.05e-08 | 1.51e-04 | 5.102 | 6 | 17 | 168 |
| GO:0003677 | DNA binding | 6.65e-07 | 9.59e-03 | 2.829 | 9 | 49 | 1218 |
| GO:0005634 | nucleus | 1.04e-06 | 1.50e-02 | 1.562 | 14 | 159 | 4559 |
| GO:0003700 | sequence-specific DNA binding transcription factor activity | 2.79e-06 | 4.02e-02 | 3.267 | 7 | 39 | 699 |
| GO:0008134 | transcription factor binding | 3.34e-06 | 4.82e-02 | 4.312 | 5 | 18 | 242 |
| GO:0005667 | transcription factor complex | 2.58e-05 | 3.71e-01 | 4.458 | 4 | 17 | 175 |
| GO:0005654 | nucleoplasm | 4.94e-05 | 7.12e-01 | 2.637 | 7 | 64 | 1082 |
| GO:0042789 | mRNA transcription from RNA polymerase II promoter | 7.82e-05 | 1.00e+00 | 7.209 | 2 | 2 | 13 |
| GO:0051019 | mitogen-activated protein kinase binding | 7.82e-05 | 1.00e+00 | 7.209 | 2 | 2 | 13 |
| GO:0003713 | transcription coactivator activity | 8.41e-05 | 1.00e+00 | 4.020 | 4 | 24 | 237 |
| GO:0031011 | Ino80 complex | 9.12e-05 | 1.00e+00 | 7.102 | 2 | 6 | 14 |
| GO:0006357 | regulation of transcription from RNA polymerase II promoter | 1.28e-04 | 1.00e+00 | 3.865 | 4 | 23 | 264 |
| GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 2.05e-04 | 1.00e+00 | 3.076 | 5 | 37 | 570 |
| GO:0051059 | NF-kappaB binding | 2.99e-04 | 1.00e+00 | 6.265 | 2 | 3 | 25 |
| GO:0006355 | regulation of transcription, DNA-templated | 3.13e-04 | 1.00e+00 | 2.533 | 6 | 43 | 997 |
| GO:0042594 | response to starvation | 4.61e-04 | 1.00e+00 | 5.955 | 2 | 4 | 31 |
| GO:0005515 | protein binding | 4.61e-04 | 1.00e+00 | 1.053 | 13 | 198 | 6024 |
| GO:0006974 | cellular response to DNA damage stimulus | 4.67e-04 | 1.00e+00 | 4.256 | 3 | 7 | 151 |
| GO:0031072 | heat shock protein binding | 5.23e-04 | 1.00e+00 | 5.865 | 2 | 2 | 33 |
| GO:0003714 | transcription corepressor activity | 7.54e-04 | 1.00e+00 | 4.018 | 3 | 11 | 178 |
| GO:1901673 | regulation of spindle assembly involved in mitosis | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
| GO:0043578 | nuclear matrix organization | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
| GO:2000016 | negative regulation of determination of dorsal identity | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
| GO:1901985 | positive regulation of protein acetylation | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
| GO:0010965 | regulation of mitotic sister chromatid separation | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
| GO:0043969 | histone H2B acetylation | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
| GO:0045083 | negative regulation of interleukin-12 biosynthetic process | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
| GO:0006404 | RNA import into nucleus | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
| GO:0090308 | regulation of methylation-dependent chromatin silencing | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
| GO:0090081 | regulation of heart induction by regulation of canonical Wnt signaling pathway | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
| GO:0071105 | response to interleukin-11 | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
| GO:0060965 | negative regulation of gene silencing by miRNA | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
| GO:0060795 | cell fate commitment involved in formation of primary germ layer | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
| GO:0060177 | regulation of angiotensin metabolic process | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
| GO:2000629 | negative regulation of miRNA metabolic process | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
| GO:0031453 | positive regulation of heterochromatin assembly | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
| GO:0050728 | negative regulation of inflammatory response | 1.51e-03 | 1.00e+00 | 5.102 | 2 | 3 | 56 |
| GO:0043627 | response to estrogen | 1.51e-03 | 1.00e+00 | 5.102 | 2 | 5 | 56 |
| GO:0032481 | positive regulation of type I interferon production | 1.78e-03 | 1.00e+00 | 4.978 | 2 | 6 | 61 |
| GO:0060242 | contact inhibition | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
| GO:0031990 | mRNA export from nucleus in response to heat stress | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 2 | 2 |
| GO:0006403 | RNA localization | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
| GO:2000483 | negative regulation of interleukin-8 secretion | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
| GO:0009786 | regulation of asymmetric cell division | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
| GO:0070840 | dynein complex binding | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
| GO:0090043 | regulation of tubulin deacetylation | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 2 | 2 |
| GO:0071389 | cellular response to mineralocorticoid stimulus | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
| GO:0046832 | negative regulation of RNA export from nucleus | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
| GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
| GO:0034696 | response to prostaglandin F | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
| GO:0000189 | MAPK import into nucleus | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
| GO:0071104 | response to interleukin-9 | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
| GO:0014737 | positive regulation of muscle atrophy | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
| GO:0035984 | cellular response to trichostatin A | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
| GO:0044324 | regulation of transcription involved in anterior/posterior axis specification | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
| GO:0003729 | mRNA binding | 2.47e-03 | 1.00e+00 | 4.739 | 2 | 4 | 72 |
| GO:0070669 | response to interleukin-2 | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
| GO:0071559 | response to transforming growth factor beta | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
| GO:0018076 | N-terminal peptidyl-lysine acetylation | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
| GO:0046914 | transition metal ion binding | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
| GO:0003340 | negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
| GO:0042306 | regulation of protein import into nucleus | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 2 | 3 |
| GO:0060913 | cardiac cell fate determination | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
| GO:1900127 | positive regulation of hyaluronan biosynthetic process | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
| GO:0050779 | RNA destabilization | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
| GO:0010560 | positive regulation of glycoprotein biosynthetic process | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
| GO:0010956 | negative regulation of calcidiol 1-monooxygenase activity | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
| GO:0071107 | response to parathyroid hormone | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
| GO:0070741 | response to interleukin-6 | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
| GO:0033256 | I-kappaB/NF-kappaB complex | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
| GO:0006405 | RNA export from nucleus | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 2 | 3 |
| GO:0003130 | BMP signaling pathway involved in heart induction | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
| GO:0032680 | regulation of tumor necrosis factor production | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
| GO:0032375 | negative regulation of cholesterol transport | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
| GO:0097157 | pre-mRNA intronic binding | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
| GO:0018393 | internal peptidyl-lysine acetylation | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
| GO:0010957 | negative regulation of vitamin D biosynthetic process | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
| GO:0032269 | negative regulation of cellular protein metabolic process | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
| GO:2000630 | positive regulation of miRNA metabolic process | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
| GO:0006999 | nuclear pore organization | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
| GO:0050693 | LBD domain binding | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
| GO:0044615 | nuclear pore nuclear basket | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
| GO:0003682 | chromatin binding | 4.29e-03 | 1.00e+00 | 3.141 | 3 | 19 | 327 |
| GO:0001714 | endodermal cell fate specification | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
| GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
| GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
| GO:0019957 | C-C chemokine binding | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
| GO:0043620 | regulation of DNA-templated transcription in response to stress | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
| GO:0070934 | CRD-mediated mRNA stabilization | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 2 | 5 |
| GO:0010884 | positive regulation of lipid storage | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
| GO:0035925 | mRNA 3'-UTR AU-rich region binding | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
| GO:0065004 | protein-DNA complex assembly | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
| GO:0010793 | regulation of mRNA export from nucleus | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
| GO:0060298 | positive regulation of sarcomere organization | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
| GO:0070849 | response to epidermal growth factor | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
| GO:0007176 | regulation of epidermal growth factor-activated receptor activity | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
| GO:0032025 | response to cobalt ion | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
| GO:0004859 | phospholipase inhibitor activity | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 1 | 6 |
| GO:0070937 | CRD-mediated mRNA stability complex | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 3 | 6 |
| GO:0070670 | response to interleukin-4 | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 1 | 6 |
| GO:0046825 | regulation of protein export from nucleus | 7.26e-03 | 1.00e+00 | 7.102 | 1 | 2 | 7 |
| GO:0060231 | mesenchymal to epithelial transition | 7.26e-03 | 1.00e+00 | 7.102 | 1 | 1 | 7 |
| GO:0071354 | cellular response to interleukin-6 | 7.26e-03 | 1.00e+00 | 7.102 | 1 | 2 | 7 |
| GO:0060712 | spongiotrophoblast layer development | 7.26e-03 | 1.00e+00 | 7.102 | 1 | 1 | 7 |
| GO:0000578 | embryonic axis specification | 7.26e-03 | 1.00e+00 | 7.102 | 1 | 1 | 7 |
| GO:0042438 | melanin biosynthetic process | 7.26e-03 | 1.00e+00 | 7.102 | 1 | 1 | 7 |
| GO:0006475 | internal protein amino acid acetylation | 7.26e-03 | 1.00e+00 | 7.102 | 1 | 1 | 7 |
| GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 7.47e-03 | 1.00e+00 | 2.285 | 4 | 41 | 789 |
| GO:0051292 | nuclear pore complex assembly | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 4 | 8 |
| GO:0007617 | mating behavior | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 8 |
| GO:0001955 | blood vessel maturation | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 8 |
| GO:0071316 | cellular response to nicotine | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 8 |
| GO:0035457 | cellular response to interferon-alpha | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 8 |
| GO:0006366 | transcription from RNA polymerase II promoter | 8.54e-03 | 1.00e+00 | 2.783 | 3 | 30 | 419 |
| GO:0042405 | nuclear inclusion body | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 2 | 9 |
| GO:0035259 | glucocorticoid receptor binding | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 1 | 9 |
| GO:0000975 | regulatory region DNA binding | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 2 | 9 |
| GO:0045793 | positive regulation of cell size | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 2 | 9 |
| GO:0060765 | regulation of androgen receptor signaling pathway | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 1 | 9 |
| GO:0010225 | response to UV-C | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 2 | 9 |
| GO:0035278 | negative regulation of translation involved in gene silencing by miRNA | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 1 | 9 |
| GO:0006983 | ER overload response | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 1 | 9 |
| GO:0043495 | protein anchor | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 1 | 9 |
| GO:0000400 | four-way junction DNA binding | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 1 | 9 |
| GO:0060711 | labyrinthine layer development | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 3 | 9 |
| GO:1900153 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | 1.04e-02 | 1.00e+00 | 6.587 | 1 | 2 | 10 |
| GO:0035413 | positive regulation of catenin import into nucleus | 1.04e-02 | 1.00e+00 | 6.587 | 1 | 2 | 10 |
| GO:0016407 | acetyltransferase activity | 1.04e-02 | 1.00e+00 | 6.587 | 1 | 2 | 10 |
| GO:0045662 | negative regulation of myoblast differentiation | 1.14e-02 | 1.00e+00 | 6.450 | 1 | 3 | 11 |
| GO:0045120 | pronucleus | 1.14e-02 | 1.00e+00 | 6.450 | 1 | 2 | 11 |
| GO:0060213 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening | 1.14e-02 | 1.00e+00 | 6.450 | 1 | 2 | 11 |
| GO:0043923 | positive regulation by host of viral transcription | 1.14e-02 | 1.00e+00 | 6.450 | 1 | 1 | 11 |
| GO:0033160 | positive regulation of protein import into nucleus, translocation | 1.14e-02 | 1.00e+00 | 6.450 | 1 | 3 | 11 |
| GO:0042975 | peroxisome proliferator activated receptor binding | 1.14e-02 | 1.00e+00 | 6.450 | 1 | 1 | 11 |
| GO:0060391 | positive regulation of SMAD protein import into nucleus | 1.14e-02 | 1.00e+00 | 6.450 | 1 | 4 | 11 |
| GO:0045893 | positive regulation of transcription, DNA-templated | 1.22e-02 | 1.00e+00 | 2.593 | 3 | 24 | 478 |
| GO:0006878 | cellular copper ion homeostasis | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 1 | 12 |
| GO:0006402 | mRNA catabolic process | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 1 | 12 |
| GO:0045947 | negative regulation of translational initiation | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 2 | 12 |
| GO:0070935 | 3'-UTR-mediated mRNA stabilization | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 3 | 12 |
| GO:0034399 | nuclear periphery | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 5 | 12 |
| GO:0070410 | co-SMAD binding | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 1 | 12 |
| GO:0035198 | miRNA binding | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 1 | 12 |
| GO:0031965 | nuclear membrane | 1.28e-02 | 1.00e+00 | 3.517 | 2 | 10 | 168 |
| GO:0071480 | cellular response to gamma radiation | 1.34e-02 | 1.00e+00 | 6.209 | 1 | 1 | 13 |
| GO:0016746 | transferase activity, transferring acyl groups | 1.34e-02 | 1.00e+00 | 6.209 | 1 | 1 | 13 |
| GO:0046688 | response to copper ion | 1.34e-02 | 1.00e+00 | 6.209 | 1 | 1 | 13 |
| GO:0005868 | cytoplasmic dynein complex | 1.34e-02 | 1.00e+00 | 6.209 | 1 | 1 | 13 |
| GO:0046827 | positive regulation of protein export from nucleus | 1.34e-02 | 1.00e+00 | 6.209 | 1 | 1 | 13 |
| GO:0010744 | positive regulation of macrophage derived foam cell differentiation | 1.45e-02 | 1.00e+00 | 6.102 | 1 | 1 | 14 |
| GO:0001967 | suckling behavior | 1.45e-02 | 1.00e+00 | 6.102 | 1 | 1 | 14 |
| GO:0031293 | membrane protein intracellular domain proteolysis | 1.45e-02 | 1.00e+00 | 6.102 | 1 | 1 | 14 |
| GO:0017091 | AU-rich element binding | 1.45e-02 | 1.00e+00 | 6.102 | 1 | 2 | 14 |
| GO:0070542 | response to fatty acid | 1.45e-02 | 1.00e+00 | 6.102 | 1 | 1 | 14 |
| GO:0071375 | cellular response to peptide hormone stimulus | 1.45e-02 | 1.00e+00 | 6.102 | 1 | 2 | 14 |
| GO:0032993 | protein-DNA complex | 1.45e-02 | 1.00e+00 | 6.102 | 1 | 2 | 14 |
| GO:0005487 | nucleocytoplasmic transporter activity | 1.45e-02 | 1.00e+00 | 6.102 | 1 | 3 | 14 |
| GO:0042307 | positive regulation of protein import into nucleus | 1.55e-02 | 1.00e+00 | 6.002 | 1 | 4 | 15 |
| GO:0001824 | blastocyst development | 1.55e-02 | 1.00e+00 | 6.002 | 1 | 2 | 15 |
| GO:1990090 | cellular response to nerve growth factor stimulus | 1.55e-02 | 1.00e+00 | 6.002 | 1 | 1 | 15 |
| GO:0060395 | SMAD protein signal transduction | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 1 | 16 |
| GO:0051276 | chromosome organization | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 2 | 16 |
| GO:0045638 | negative regulation of myeloid cell differentiation | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 1 | 16 |
| GO:0048593 | camera-type eye morphogenesis | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 1 | 16 |
| GO:0012506 | vesicle membrane | 1.75e-02 | 1.00e+00 | 5.822 | 1 | 1 | 17 |
| GO:0090316 | positive regulation of intracellular protein transport | 1.75e-02 | 1.00e+00 | 5.822 | 1 | 2 | 17 |
| GO:0006915 | apoptotic process | 1.83e-02 | 1.00e+00 | 2.378 | 3 | 12 | 555 |
| GO:0071889 | 14-3-3 protein binding | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 2 | 18 |
| GO:0045773 | positive regulation of axon extension | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 1 | 18 |
| GO:0033613 | activating transcription factor binding | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 3 | 18 |
| GO:0030318 | melanocyte differentiation | 1.96e-02 | 1.00e+00 | 5.661 | 1 | 3 | 19 |
| GO:0035257 | nuclear hormone receptor binding | 1.96e-02 | 1.00e+00 | 5.661 | 1 | 1 | 19 |
| GO:0044822 | poly(A) RNA binding | 2.03e-02 | 1.00e+00 | 1.865 | 4 | 50 | 1056 |
| GO:0071549 | cellular response to dexamethasone stimulus | 2.06e-02 | 1.00e+00 | 5.587 | 1 | 3 | 20 |
| GO:0010942 | positive regulation of cell death | 2.06e-02 | 1.00e+00 | 5.587 | 1 | 1 | 20 |
| GO:0032757 | positive regulation of interleukin-8 production | 2.06e-02 | 1.00e+00 | 5.587 | 1 | 1 | 20 |
| GO:0043473 | pigmentation | 2.06e-02 | 1.00e+00 | 5.587 | 1 | 1 | 20 |
| GO:0043393 | regulation of protein binding | 2.06e-02 | 1.00e+00 | 5.587 | 1 | 1 | 20 |
| GO:0032967 | positive regulation of collagen biosynthetic process | 2.16e-02 | 1.00e+00 | 5.517 | 1 | 3 | 21 |
| GO:0045862 | positive regulation of proteolysis | 2.16e-02 | 1.00e+00 | 5.517 | 1 | 2 | 21 |
| GO:0034341 | response to interferon-gamma | 2.16e-02 | 1.00e+00 | 5.517 | 1 | 2 | 21 |
| GO:0000123 | histone acetyltransferase complex | 2.16e-02 | 1.00e+00 | 5.517 | 1 | 6 | 21 |
| GO:0042803 | protein homodimerization activity | 2.19e-02 | 1.00e+00 | 2.277 | 3 | 19 | 595 |
| GO:0005737 | cytoplasm | 2.24e-02 | 1.00e+00 | 1.030 | 8 | 124 | 3767 |
| GO:0003823 | antigen binding | 2.26e-02 | 1.00e+00 | 5.450 | 1 | 2 | 22 |
| GO:0036464 | cytoplasmic ribonucleoprotein granule | 2.26e-02 | 1.00e+00 | 5.450 | 1 | 2 | 22 |
| GO:0007399 | nervous system development | 2.34e-02 | 1.00e+00 | 3.057 | 2 | 6 | 231 |
| GO:0030511 | positive regulation of transforming growth factor beta receptor signaling pathway | 2.37e-02 | 1.00e+00 | 5.386 | 1 | 2 | 23 |
| GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | 2.37e-02 | 1.00e+00 | 5.386 | 1 | 1 | 23 |
| GO:0043388 | positive regulation of DNA binding | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 2 | 24 |
| GO:0043425 | bHLH transcription factor binding | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 1 | 24 |
| GO:0006611 | protein export from nucleus | 2.57e-02 | 1.00e+00 | 5.265 | 1 | 3 | 25 |
| GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening | 2.57e-02 | 1.00e+00 | 5.265 | 1 | 3 | 25 |
| GO:0031519 | PcG protein complex | 2.57e-02 | 1.00e+00 | 5.265 | 1 | 1 | 25 |
| GO:0035329 | hippo signaling | 2.67e-02 | 1.00e+00 | 5.209 | 1 | 5 | 26 |
| GO:0000976 | transcription regulatory region sequence-specific DNA binding | 2.67e-02 | 1.00e+00 | 5.209 | 1 | 3 | 26 |
| GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 2.67e-02 | 1.00e+00 | 5.209 | 1 | 1 | 26 |
| GO:0051209 | release of sequestered calcium ion into cytosol | 2.67e-02 | 1.00e+00 | 5.209 | 1 | 1 | 26 |
| GO:0048565 | digestive tract development | 2.67e-02 | 1.00e+00 | 5.209 | 1 | 2 | 26 |
| GO:0015631 | tubulin binding | 2.77e-02 | 1.00e+00 | 5.154 | 1 | 2 | 27 |
| GO:0001656 | metanephros development | 2.77e-02 | 1.00e+00 | 5.154 | 1 | 1 | 27 |
| GO:0006913 | nucleocytoplasmic transport | 2.77e-02 | 1.00e+00 | 5.154 | 1 | 1 | 27 |
| GO:0034612 | response to tumor necrosis factor | 2.77e-02 | 1.00e+00 | 5.154 | 1 | 2 | 27 |
| GO:0043967 | histone H4 acetylation | 2.77e-02 | 1.00e+00 | 5.154 | 1 | 1 | 27 |
| GO:0003727 | single-stranded RNA binding | 2.87e-02 | 1.00e+00 | 5.102 | 1 | 2 | 28 |
| GO:0050714 | positive regulation of protein secretion | 2.87e-02 | 1.00e+00 | 5.102 | 1 | 3 | 28 |
| GO:0034605 | cellular response to heat | 2.87e-02 | 1.00e+00 | 5.102 | 1 | 1 | 28 |
| GO:0010467 | gene expression | 2.98e-02 | 1.00e+00 | 2.108 | 3 | 45 | 669 |
| GO:0030901 | midbrain development | 2.98e-02 | 1.00e+00 | 5.051 | 1 | 1 | 29 |
| GO:0072686 | mitotic spindle | 2.98e-02 | 1.00e+00 | 5.051 | 1 | 3 | 29 |
| GO:0070555 | response to interleukin-1 | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 2 | 30 |
| GO:0006606 | protein import into nucleus | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 2 | 30 |
| GO:0031647 | regulation of protein stability | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 4 | 30 |
| GO:0010827 | regulation of glucose transport | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 4 | 30 |
| GO:0034644 | cellular response to UV | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 1 | 30 |
| GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 1 | 30 |
| GO:0005544 | calcium-dependent phospholipid binding | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 1 | 30 |
| GO:0010494 | cytoplasmic stress granule | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 2 | 30 |
| GO:0001890 | placenta development | 3.18e-02 | 1.00e+00 | 4.955 | 1 | 3 | 31 |
| GO:0007094 | mitotic spindle assembly checkpoint | 3.18e-02 | 1.00e+00 | 4.955 | 1 | 3 | 31 |
| GO:0071347 | cellular response to interleukin-1 | 3.18e-02 | 1.00e+00 | 4.955 | 1 | 2 | 31 |
| GO:0005829 | cytosol | 3.24e-02 | 1.00e+00 | 1.209 | 6 | 86 | 2496 |
| GO:0006954 | inflammatory response | 3.27e-02 | 1.00e+00 | 2.795 | 2 | 6 | 277 |
| GO:0043491 | protein kinase B signaling | 3.28e-02 | 1.00e+00 | 4.909 | 1 | 2 | 32 |
| GO:1903507 | negative regulation of nucleic acid-templated transcription | 3.28e-02 | 1.00e+00 | 4.909 | 1 | 2 | 32 |
| GO:0001756 | somitogenesis | 3.38e-02 | 1.00e+00 | 4.865 | 1 | 1 | 33 |
| GO:0071333 | cellular response to glucose stimulus | 3.38e-02 | 1.00e+00 | 4.865 | 1 | 1 | 33 |
| GO:0030178 | negative regulation of Wnt signaling pathway | 3.58e-02 | 1.00e+00 | 4.780 | 1 | 4 | 35 |
| GO:0007077 | mitotic nuclear envelope disassembly | 3.68e-02 | 1.00e+00 | 4.739 | 1 | 4 | 36 |
| GO:0001102 | RNA polymerase II activating transcription factor binding | 3.68e-02 | 1.00e+00 | 4.739 | 1 | 1 | 36 |
| GO:0045668 | negative regulation of osteoblast differentiation | 3.68e-02 | 1.00e+00 | 4.739 | 1 | 1 | 36 |
| GO:0030154 | cell differentiation | 3.81e-02 | 1.00e+00 | 2.676 | 2 | 5 | 301 |
| GO:0031490 | chromatin DNA binding | 3.88e-02 | 1.00e+00 | 4.661 | 1 | 2 | 38 |
| GO:0032092 | positive regulation of protein binding | 3.88e-02 | 1.00e+00 | 4.661 | 1 | 2 | 38 |
| GO:0050681 | androgen receptor binding | 3.88e-02 | 1.00e+00 | 4.661 | 1 | 1 | 38 |
| GO:0008645 | hexose transport | 3.98e-02 | 1.00e+00 | 4.624 | 1 | 4 | 39 |
| GO:0046332 | SMAD binding | 4.08e-02 | 1.00e+00 | 4.587 | 1 | 2 | 40 |
| GO:0071320 | cellular response to cAMP | 4.08e-02 | 1.00e+00 | 4.587 | 1 | 1 | 40 |
| GO:0035019 | somatic stem cell maintenance | 4.08e-02 | 1.00e+00 | 4.587 | 1 | 6 | 40 |
| GO:0050885 | neuromuscular process controlling balance | 4.08e-02 | 1.00e+00 | 4.587 | 1 | 2 | 40 |
| GO:0007519 | skeletal muscle tissue development | 4.08e-02 | 1.00e+00 | 4.587 | 1 | 2 | 40 |
| GO:0070301 | cellular response to hydrogen peroxide | 4.18e-02 | 1.00e+00 | 4.552 | 1 | 2 | 41 |
| GO:0019898 | extrinsic component of membrane | 4.28e-02 | 1.00e+00 | 4.517 | 1 | 2 | 42 |
| GO:0001658 | branching involved in ureteric bud morphogenesis | 4.38e-02 | 1.00e+00 | 4.483 | 1 | 3 | 43 |
| GO:0004402 | histone acetyltransferase activity | 4.38e-02 | 1.00e+00 | 4.483 | 1 | 6 | 43 |
| GO:0008283 | cell proliferation | 4.45e-02 | 1.00e+00 | 2.552 | 2 | 14 | 328 |
| GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding | 4.48e-02 | 1.00e+00 | 4.450 | 1 | 4 | 44 |
| GO:0003712 | transcription cofactor activity | 4.48e-02 | 1.00e+00 | 4.450 | 1 | 8 | 44 |
| GO:0045727 | positive regulation of translation | 4.48e-02 | 1.00e+00 | 4.450 | 1 | 2 | 44 |
| GO:0051591 | response to cAMP | 4.58e-02 | 1.00e+00 | 4.417 | 1 | 4 | 45 |
| GO:0043966 | histone H3 acetylation | 4.58e-02 | 1.00e+00 | 4.417 | 1 | 5 | 45 |
| GO:0001047 | core promoter binding | 4.58e-02 | 1.00e+00 | 4.417 | 1 | 5 | 45 |
| GO:0043525 | positive regulation of neuron apoptotic process | 4.68e-02 | 1.00e+00 | 4.386 | 1 | 4 | 46 |
| GO:0019827 | stem cell maintenance | 4.78e-02 | 1.00e+00 | 4.355 | 1 | 7 | 47 |
| GO:0003723 | RNA binding | 4.80e-02 | 1.00e+00 | 2.491 | 2 | 18 | 342 |
| GO:0090263 | positive regulation of canonical Wnt signaling pathway | 4.88e-02 | 1.00e+00 | 4.324 | 1 | 3 | 48 |
| GO:0043565 | sequence-specific DNA binding | 4.90e-02 | 1.00e+00 | 2.475 | 2 | 11 | 346 |
| GO:0030900 | forebrain development | 4.98e-02 | 1.00e+00 | 4.294 | 1 | 1 | 49 |
| GO:0035690 | cellular response to drug | 4.98e-02 | 1.00e+00 | 4.294 | 1 | 3 | 49 |
| GO:0006986 | response to unfolded protein | 5.08e-02 | 1.00e+00 | 4.265 | 1 | 4 | 50 |
| GO:0034097 | response to cytokine | 5.08e-02 | 1.00e+00 | 4.265 | 1 | 2 | 50 |
| GO:0034976 | response to endoplasmic reticulum stress | 5.18e-02 | 1.00e+00 | 4.237 | 1 | 2 | 51 |
| GO:0045454 | cell redox homeostasis | 5.18e-02 | 1.00e+00 | 4.237 | 1 | 1 | 51 |
| GO:0009611 | response to wounding | 5.28e-02 | 1.00e+00 | 4.209 | 1 | 5 | 52 |
| GO:0007623 | circadian rhythm | 5.38e-02 | 1.00e+00 | 4.181 | 1 | 1 | 53 |
| GO:0032868 | response to insulin | 5.38e-02 | 1.00e+00 | 4.181 | 1 | 1 | 53 |
| GO:0000288 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | 5.38e-02 | 1.00e+00 | 4.181 | 1 | 4 | 53 |
| GO:0051592 | response to calcium ion | 5.57e-02 | 1.00e+00 | 4.128 | 1 | 1 | 55 |
| GO:0002039 | p53 binding | 5.57e-02 | 1.00e+00 | 4.128 | 1 | 4 | 55 |
| GO:0015758 | glucose transport | 5.57e-02 | 1.00e+00 | 4.128 | 1 | 4 | 55 |
| GO:0071300 | cellular response to retinoic acid | 5.57e-02 | 1.00e+00 | 4.128 | 1 | 1 | 55 |
| GO:0000724 | double-strand break repair via homologous recombination | 5.57e-02 | 1.00e+00 | 4.128 | 1 | 2 | 55 |
| GO:0006351 | transcription, DNA-templated | 5.59e-02 | 1.00e+00 | 1.411 | 4 | 57 | 1446 |
| GO:0001570 | vasculogenesis | 5.67e-02 | 1.00e+00 | 4.102 | 1 | 2 | 56 |
| GO:0048306 | calcium-dependent protein binding | 5.67e-02 | 1.00e+00 | 4.102 | 1 | 2 | 56 |
| GO:0008203 | cholesterol metabolic process | 5.77e-02 | 1.00e+00 | 4.076 | 1 | 2 | 57 |
| GO:0005643 | nuclear pore | 5.77e-02 | 1.00e+00 | 4.076 | 1 | 11 | 57 |
| GO:0006396 | RNA processing | 5.97e-02 | 1.00e+00 | 4.027 | 1 | 5 | 59 |
| GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity | 5.97e-02 | 1.00e+00 | 4.027 | 1 | 6 | 59 |
| GO:0001078 | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription | 5.97e-02 | 1.00e+00 | 4.027 | 1 | 5 | 59 |
| GO:0008013 | beta-catenin binding | 6.06e-02 | 1.00e+00 | 4.002 | 1 | 9 | 60 |
| GO:0000278 | mitotic cell cycle | 6.10e-02 | 1.00e+00 | 2.298 | 2 | 15 | 391 |
| GO:0030855 | epithelial cell differentiation | 6.16e-02 | 1.00e+00 | 3.978 | 1 | 1 | 61 |
| GO:0006987 | activation of signaling protein activity involved in unfolded protein response | 6.16e-02 | 1.00e+00 | 3.978 | 1 | 2 | 61 |
| GO:0032088 | negative regulation of NF-kappaB transcription factor activity | 6.36e-02 | 1.00e+00 | 3.932 | 1 | 3 | 63 |
| GO:0004867 | serine-type endopeptidase inhibitor activity | 6.36e-02 | 1.00e+00 | 3.932 | 1 | 3 | 63 |
| GO:0000776 | kinetochore | 6.36e-02 | 1.00e+00 | 3.932 | 1 | 5 | 63 |
| GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | 6.36e-02 | 1.00e+00 | 3.932 | 1 | 4 | 63 |
| GO:0009986 | cell surface | 6.41e-02 | 1.00e+00 | 2.258 | 2 | 9 | 402 |
| GO:0006310 | DNA recombination | 6.55e-02 | 1.00e+00 | 3.887 | 1 | 7 | 65 |
| GO:0071260 | cellular response to mechanical stimulus | 6.55e-02 | 1.00e+00 | 3.887 | 1 | 4 | 65 |
| GO:0034166 | toll-like receptor 10 signaling pathway | 6.55e-02 | 1.00e+00 | 3.887 | 1 | 4 | 65 |
| GO:0034146 | toll-like receptor 5 signaling pathway | 6.55e-02 | 1.00e+00 | 3.887 | 1 | 4 | 65 |
| GO:0045892 | negative regulation of transcription, DNA-templated | 6.72e-02 | 1.00e+00 | 2.219 | 2 | 24 | 413 |
| GO:0010468 | regulation of gene expression | 6.85e-02 | 1.00e+00 | 3.822 | 1 | 2 | 68 |
| GO:0043066 | negative regulation of apoptotic process | 7.03e-02 | 1.00e+00 | 2.181 | 2 | 16 | 424 |
| GO:0038123 | toll-like receptor TLR1:TLR2 signaling pathway | 7.14e-02 | 1.00e+00 | 3.759 | 1 | 4 | 71 |
| GO:0007626 | locomotory behavior | 7.14e-02 | 1.00e+00 | 3.759 | 1 | 2 | 71 |
| GO:0038124 | toll-like receptor TLR6:TLR2 signaling pathway | 7.14e-02 | 1.00e+00 | 3.759 | 1 | 4 | 71 |
| GO:0043086 | negative regulation of catalytic activity | 7.24e-02 | 1.00e+00 | 3.739 | 1 | 2 | 72 |
| GO:0034162 | toll-like receptor 9 signaling pathway | 7.24e-02 | 1.00e+00 | 3.739 | 1 | 4 | 72 |
| GO:0030324 | lung development | 7.24e-02 | 1.00e+00 | 3.739 | 1 | 1 | 72 |
| GO:0034134 | toll-like receptor 2 signaling pathway | 7.33e-02 | 1.00e+00 | 3.719 | 1 | 4 | 73 |
| GO:0000785 | chromatin | 7.33e-02 | 1.00e+00 | 3.719 | 1 | 6 | 73 |
| GO:0002020 | protease binding | 7.43e-02 | 1.00e+00 | 3.700 | 1 | 6 | 74 |
| GO:0000981 | sequence-specific DNA binding RNA polymerase II transcription factor activity | 7.43e-02 | 1.00e+00 | 3.700 | 1 | 4 | 74 |
| GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 7.53e-02 | 1.00e+00 | 3.680 | 1 | 1 | 75 |
| GO:0035666 | TRIF-dependent toll-like receptor signaling pathway | 7.62e-02 | 1.00e+00 | 3.661 | 1 | 3 | 76 |
| GO:0001889 | liver development | 7.72e-02 | 1.00e+00 | 3.642 | 1 | 3 | 77 |
| GO:0071013 | catalytic step 2 spliceosome | 7.82e-02 | 1.00e+00 | 3.624 | 1 | 7 | 78 |
| GO:0002756 | MyD88-independent toll-like receptor signaling pathway | 7.82e-02 | 1.00e+00 | 3.624 | 1 | 3 | 78 |
| GO:0034138 | toll-like receptor 3 signaling pathway | 7.91e-02 | 1.00e+00 | 3.605 | 1 | 3 | 79 |
| GO:0030968 | endoplasmic reticulum unfolded protein response | 7.91e-02 | 1.00e+00 | 3.605 | 1 | 2 | 79 |
| GO:0002755 | MyD88-dependent toll-like receptor signaling pathway | 8.01e-02 | 1.00e+00 | 3.587 | 1 | 5 | 80 |
| GO:0071222 | cellular response to lipopolysaccharide | 8.10e-02 | 1.00e+00 | 3.569 | 1 | 4 | 81 |
| GO:0009653 | anatomical structure morphogenesis | 8.30e-02 | 1.00e+00 | 3.534 | 1 | 2 | 83 |
| GO:0009952 | anterior/posterior pattern specification | 8.30e-02 | 1.00e+00 | 3.534 | 1 | 4 | 83 |
| GO:0050852 | T cell receptor signaling pathway | 8.49e-02 | 1.00e+00 | 3.500 | 1 | 2 | 85 |
| GO:0009887 | organ morphogenesis | 8.58e-02 | 1.00e+00 | 3.483 | 1 | 5 | 86 |
| GO:0003690 | double-stranded DNA binding | 8.58e-02 | 1.00e+00 | 3.483 | 1 | 3 | 86 |
| GO:0090090 | negative regulation of canonical Wnt signaling pathway | 8.58e-02 | 1.00e+00 | 3.483 | 1 | 8 | 86 |
| GO:0045471 | response to ethanol | 8.58e-02 | 1.00e+00 | 3.483 | 1 | 3 | 86 |
| GO:0006979 | response to oxidative stress | 8.68e-02 | 1.00e+00 | 3.466 | 1 | 6 | 87 |
| GO:0042802 | identical protein binding | 8.85e-02 | 1.00e+00 | 1.990 | 2 | 19 | 484 |
| GO:0016363 | nuclear matrix | 9.06e-02 | 1.00e+00 | 3.401 | 1 | 6 | 91 |
| GO:0001649 | osteoblast differentiation | 9.16e-02 | 1.00e+00 | 3.386 | 1 | 5 | 92 |
| GO:0071456 | cellular response to hypoxia | 9.16e-02 | 1.00e+00 | 3.386 | 1 | 3 | 92 |
| GO:0051091 | positive regulation of sequence-specific DNA binding transcription factor activity | 9.16e-02 | 1.00e+00 | 3.386 | 1 | 7 | 92 |
| GO:0005770 | late endosome | 9.25e-02 | 1.00e+00 | 3.370 | 1 | 2 | 93 |
| GO:0034142 | toll-like receptor 4 signaling pathway | 9.54e-02 | 1.00e+00 | 3.324 | 1 | 4 | 96 |
| GO:0051726 | regulation of cell cycle | 9.63e-02 | 1.00e+00 | 3.309 | 1 | 5 | 97 |
| GO:0001934 | positive regulation of protein phosphorylation | 1.03e-01 | 1.00e+00 | 3.209 | 1 | 5 | 104 |
| GO:0010951 | negative regulation of endopeptidase activity | 1.03e-01 | 1.00e+00 | 3.209 | 1 | 6 | 104 |
| GO:0005938 | cell cortex | 1.03e-01 | 1.00e+00 | 3.209 | 1 | 5 | 104 |
| GO:0016032 | viral process | 1.05e-01 | 1.00e+00 | 1.848 | 2 | 26 | 534 |
| GO:0002224 | toll-like receptor signaling pathway | 1.08e-01 | 1.00e+00 | 3.141 | 1 | 4 | 109 |
| GO:0030529 | ribonucleoprotein complex | 1.10e-01 | 1.00e+00 | 3.102 | 1 | 5 | 112 |
| GO:0005635 | nuclear envelope | 1.11e-01 | 1.00e+00 | 3.089 | 1 | 5 | 113 |
| GO:0043524 | negative regulation of neuron apoptotic process | 1.15e-01 | 1.00e+00 | 3.039 | 1 | 5 | 117 |
| GO:0046983 | protein dimerization activity | 1.16e-01 | 1.00e+00 | 3.027 | 1 | 5 | 118 |
| GO:0006325 | chromatin organization | 1.16e-01 | 1.00e+00 | 3.027 | 1 | 12 | 118 |
| GO:0007219 | Notch signaling pathway | 1.18e-01 | 1.00e+00 | 3.002 | 1 | 5 | 120 |
| GO:0032496 | response to lipopolysaccharide | 1.19e-01 | 1.00e+00 | 2.990 | 1 | 4 | 121 |
| GO:0008201 | heparin binding | 1.20e-01 | 1.00e+00 | 2.978 | 1 | 1 | 122 |
| GO:0051092 | positive regulation of NF-kappaB transcription factor activity | 1.22e-01 | 1.00e+00 | 2.955 | 1 | 5 | 124 |
| GO:0007050 | cell cycle arrest | 1.22e-01 | 1.00e+00 | 2.955 | 1 | 5 | 124 |
| GO:0007179 | transforming growth factor beta receptor signaling pathway | 1.25e-01 | 1.00e+00 | 2.909 | 1 | 11 | 128 |
| GO:0045087 | innate immune response | 1.26e-01 | 1.00e+00 | 1.690 | 2 | 15 | 596 |
| GO:0005215 | transporter activity | 1.27e-01 | 1.00e+00 | 2.887 | 1 | 3 | 130 |
| GO:0000086 | G2/M transition of mitotic cell cycle | 1.33e-01 | 1.00e+00 | 2.822 | 1 | 4 | 136 |
| GO:0016055 | Wnt signaling pathway | 1.34e-01 | 1.00e+00 | 2.801 | 1 | 4 | 138 |
| GO:0007507 | heart development | 1.35e-01 | 1.00e+00 | 2.790 | 1 | 7 | 139 |
| GO:0010628 | positive regulation of gene expression | 1.42e-01 | 1.00e+00 | 2.719 | 1 | 7 | 146 |
| GO:0001666 | response to hypoxia | 1.44e-01 | 1.00e+00 | 2.690 | 1 | 7 | 149 |
| GO:0008022 | protein C-terminus binding | 1.55e-01 | 1.00e+00 | 2.578 | 1 | 8 | 161 |
| GO:0000398 | mRNA splicing, via spliceosome | 1.58e-01 | 1.00e+00 | 2.552 | 1 | 15 | 164 |
| GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.59e-01 | 1.00e+00 | 2.543 | 1 | 12 | 165 |
| GO:0007420 | brain development | 1.60e-01 | 1.00e+00 | 2.525 | 1 | 2 | 167 |
| GO:0038095 | Fc-epsilon receptor signaling pathway | 1.61e-01 | 1.00e+00 | 2.517 | 1 | 5 | 168 |
| GO:0031625 | ubiquitin protein ligase binding | 1.70e-01 | 1.00e+00 | 2.433 | 1 | 5 | 178 |
| GO:0032403 | protein complex binding | 1.74e-01 | 1.00e+00 | 2.393 | 1 | 6 | 183 |
| GO:0006367 | transcription initiation from RNA polymerase II promoter | 1.75e-01 | 1.00e+00 | 2.386 | 1 | 22 | 184 |
| GO:0019221 | cytokine-mediated signaling pathway | 2.07e-01 | 1.00e+00 | 2.121 | 1 | 8 | 221 |
| GO:0016071 | mRNA metabolic process | 2.09e-01 | 1.00e+00 | 2.108 | 1 | 8 | 223 |
| GO:0007067 | mitotic nuclear division | 2.12e-01 | 1.00e+00 | 2.083 | 1 | 6 | 227 |
| GO:0008380 | RNA splicing | 2.13e-01 | 1.00e+00 | 2.076 | 1 | 22 | 228 |
| GO:0016070 | RNA metabolic process | 2.28e-01 | 1.00e+00 | 1.961 | 1 | 8 | 247 |
| GO:0005975 | carbohydrate metabolic process | 2.33e-01 | 1.00e+00 | 1.926 | 1 | 8 | 253 |
| GO:0005730 | nucleolus | 2.39e-01 | 1.00e+00 | 0.814 | 3 | 66 | 1641 |
| GO:0006281 | DNA repair | 2.40e-01 | 1.00e+00 | 1.881 | 1 | 14 | 261 |
| GO:0007283 | spermatogenesis | 2.41e-01 | 1.00e+00 | 1.876 | 1 | 3 | 262 |
| GO:0048011 | neurotrophin TRK receptor signaling pathway | 2.46e-01 | 1.00e+00 | 1.838 | 1 | 7 | 269 |
| GO:0030198 | extracellular matrix organization | 2.57e-01 | 1.00e+00 | 1.765 | 1 | 6 | 283 |
| GO:0007186 | G-protein coupled receptor signaling pathway | 2.62e-01 | 1.00e+00 | 1.734 | 1 | 1 | 289 |
| GO:0035556 | intracellular signal transduction | 2.73e-01 | 1.00e+00 | 1.666 | 1 | 9 | 303 |
| GO:0008270 | zinc ion binding | 2.78e-01 | 1.00e+00 | 0.948 | 2 | 27 | 997 |
| GO:0007275 | multicellular organismal development | 2.83e-01 | 1.00e+00 | 1.605 | 1 | 7 | 316 |
| GO:0019901 | protein kinase binding | 2.84e-01 | 1.00e+00 | 1.601 | 1 | 18 | 317 |
| GO:0046982 | protein heterodimerization activity | 3.30e-01 | 1.00e+00 | 1.339 | 1 | 8 | 380 |
| GO:0055085 | transmembrane transport | 3.68e-01 | 1.00e+00 | 1.144 | 1 | 8 | 435 |
| GO:0044267 | cellular protein metabolic process | 3.94e-01 | 1.00e+00 | 1.020 | 1 | 20 | 474 |
| GO:0048471 | perinuclear region of cytoplasm | 4.12e-01 | 1.00e+00 | 0.938 | 1 | 8 | 502 |
| GO:0005509 | calcium ion binding | 4.30e-01 | 1.00e+00 | 0.857 | 1 | 11 | 531 |
| GO:0005783 | endoplasmic reticulum | 4.46e-01 | 1.00e+00 | 0.790 | 1 | 13 | 556 |
| GO:0016020 | membrane | 5.36e-01 | 1.00e+00 | 0.194 | 2 | 46 | 1681 |
| GO:0007165 | signal transduction | 6.23e-01 | 1.00e+00 | 0.084 | 1 | 13 | 907 |
| GO:0005739 | mitochondrion | 6.59e-01 | 1.00e+00 | -0.054 | 1 | 23 | 998 |
| GO:0044281 | small molecule metabolic process | 7.32e-01 | 1.00e+00 | -0.333 | 1 | 20 | 1211 |
| GO:0070062 | extracellular vesicular exosome | 7.40e-01 | 1.00e+00 | -0.320 | 2 | 57 | 2400 |
| GO:0005524 | ATP binding | 7.57e-01 | 1.00e+00 | -0.433 | 1 | 31 | 1298 |
| GO:0046872 | metal ion binding | 7.60e-01 | 1.00e+00 | -0.443 | 1 | 29 | 1307 |
| GO:0005886 | plasma membrane | 7.79e-01 | 1.00e+00 | -0.425 | 2 | 49 | 2582 |
| GO:0016021 | integral component of membrane | 8.91e-01 | 1.00e+00 | -1.044 | 1 | 17 | 1982 |