meta-int-snw-5216

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-11277 wolf-screen-ratio-mammosphere-adherent 0.882 1.09e-07 9.11e-04 1.96e-03 10 9
int-snw-5216 wolf-screen-ratio-mammosphere-adherent 1.002 3.25e-18 5.25e-04 1.26e-02 12 11
reg-snw-4522 wolf-screen-ratio-mammosphere-adherent 0.815 1.50e-06 3.75e-03 6.95e-03 14 12
reg-snw-5887 wolf-screen-ratio-mammosphere-adherent 0.858 2.95e-07 1.57e-03 3.19e-03 5 5
reg-snw-5905 wolf-screen-ratio-mammosphere-adherent 0.816 1.47e-06 3.71e-03 6.88e-03 6 6
reg-snw-56655 wolf-screen-ratio-mammosphere-adherent 0.828 9.29e-07 2.91e-03 5.53e-03 8 7
reg-snw-317781 wolf-screen-ratio-mammosphere-adherent 0.823 1.13e-06 3.23e-03 6.07e-03 9 9
reg-snw-1434 wolf-screen-ratio-mammosphere-adherent 0.865 2.23e-07 1.35e-03 2.78e-03 9 7
reg-snw-10213 wolf-screen-ratio-mammosphere-adherent 0.815 1.49e-06 3.74e-03 6.93e-03 7 6
reg-snw-5686 wolf-screen-ratio-mammosphere-adherent 0.878 1.30e-07 1.01e-03 2.15e-03 5 4
wolf-screen-ratio-mammosphere-adherent-meta-int-snw-5216 subnetwork

Genes (42)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
PSMB1 5689 610.6880.901113Yes-
PSMA3 5684 900.5330.815238Yes-
PSMA2 5683 1121.0931.106108Yes-
POLR2F 5435 620.8910.95626Yes-
CSE1L 1434 410.3040.86554Yes-
VARS 7407 860.5491.002204Yes-
DDX51 317781 530.0590.823210Yes-
RPA2 6118 961.2501.15176Yes-
CAD 790 910.8070.973400--
EIF6 3692 670.7000.876316Yes-
CCNA2 890 540.5500.973246Yes-
PSMD1 5707 860.8360.830118Yes-
EIF2S2 8894 391.0750.940103Yes-
PFN1 5216 10-0.1431.00278--
RAD23B 5887 70.1580.85811Yes-
EFTUD2 9343 930.8830.956108Yes-
PSMD14 10213 440.2990.81532--
TUBG1 7283 980.9740.97391Yes-
PSMD11 5717 1241.0951.106218Yes-
RAN 5901 890.6320.899258Yes-
PRMT3 10196 490.4310.81526--
PSMA5 5686 350.3780.87833--
MTHFD1 4522 490.1940.81526Yes-
RBX1 9978 1151.1850.934148Yes-
PSMC3 5702 510.7191.002276Yes-
HNRNPC 3183 1081.8120.973181Yes-
PSMB7 5695 1180.9820.93490Yes-
PSMA1 5682 1000.9960.878152Yes-
RANGAP1 5905 11-0.0460.81674Yes-
TREX1 11277 51-0.0510.88291Yes-
POLE4 56655 630.1770.82856--
PSMB3 5691 640.6680.90119Yes-
RPSA 3921 1201.3271.151152Yes-
RPA1 6117 510.4250.86574--
CDC16 8881 530.9501.02080Yes-
RUVBL1 8607 950.7200.973469Yes-
PSMD3 5709 1000.9861.106201Yes-
CLTC 1213 560.8841.138247Yes-
PSMB2 5690 1160.8770.956169Yes-
ACTB 60 1341.1531.151610Yes-
RUVBL2 10856 950.6930.956532Yes-
PSMD6 9861 790.8480.878143Yes-

Interactions (223)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMD1 5707 RAD23B 5887 pp -- int.I2D: BioGrid_Yeast, IntAct_Rat, IntAct_Yeast, Krogan_Core, MINT, MINT_Yeast;
int.Mint: MI:0915(physical association)
PSMA3 5684 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, Krogan_Core
PSMD11 5717 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, INTEROLOG
HNRNPC 3183 PSMA3 5684 pp -- int.I2D: BioGrid
PSMB2 5690 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMA1 5682 PSMB2 5690 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
PSMA3 5684 RAD23B 5887 pp -- int.I2D: BioGrid
PSMA5 5686 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMD11 5717 RUVBL1 8607 pp -- int.I2D: YeastLow
PSMA1 5682 PSMB1 5689 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, BIND_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, IntAct, IntAct_Mouse, IntAct_Yeast, Yu_GoldStd
RAD23B 5887 PSMD6 9861 pp -- int.I2D: MINT;
int.Mint: MI:0915(physical association)
CSE1L 1434 PSMD14 10213 pd < reg.ITFP.txt: no annot
CSE1L 1434 RAN 5901 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid_Yeast, HPRD, IntAct_Yeast, MIPS, IntAct, INTEROLOG;
int.HPRD: in vitro
CAD 790 CDC16 8881 pp -- int.I2D: IntAct_Yeast
PSMB1 5689 PSMC3 5702 pp -- int.I2D: YeastLow
EFTUD2 9343 RUVBL2 10856 pd < reg.ITFP.txt: no annot
EFTUD2 9343 RUVBL2 10856 pp -- int.I2D: BioGrid
CAD 790 RPA1 6117 pd < reg.ITFP.txt: no annot
MTHFD1 4522 PSMA3 5684 pp -- int.I2D: BioGrid
PSMB2 5690 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMD11 5717 RAD23B 5887 pp -- int.I2D: YeastLow, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast
PSMC3 5702 VARS 7407 pp -- int.I2D: BioGrid_Yeast
PSMD1 5707 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, Krogan_Core
PSMA5 5686 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
ACTB 60 CLTC 1213 pp -- int.I2D: IntAct_Yeast
ACTB 60 RUVBL1 8607 pp -- int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PSMB7 5695 RAD23B 5887 pp -- int.I2D: BioGrid_Yeast, BIND_Yeast, MIPS
CCNA2 890 RUVBL1 8607 pd <> reg.ITFP.txt: no annot
PSMB3 5691 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPA1 6117 RUVBL1 8607 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
RPA1 6117 VARS 7407 pp -- int.I2D: YeastLow
CAD 790 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow
PSMB1 5689 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RAN 5901 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastHigh, IntAct, Yu_GoldStd;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
PSMB2 5690 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMC3 5702 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMB3 5691 PSMD3 5709 pp -- int.I2D: YeastLow
PSMA2 5683 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
CAD 790 RUVBL1 8607 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL1 8607 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMD3 5709 RAD23B 5887 pd > reg.ITFP.txt: no annot
PSMD3 5709 RAD23B 5887 pp -- int.I2D: YeastLow, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast
PSMA2 5683 PSMA5 5686 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, MINT_Yeast, YeastHigh, BIND_Yeast, IntAct_Fly, Krogan_Core
RPA1 6117 TREX1 11277 pp -- int.I2D: BCI;
int.HPRD: in vitro
PSMA3 5684 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMD14 10213 pp -- int.I2D: BioGrid, BioGrid_Yeast
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
CCNA2 890 CSE1L 1434 pd > reg.ITFP.txt: no annot
RPA1 6117 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMB1 5689 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, MINT, YeastHigh, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast;
int.Mint: MI:0915(physical association)
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
TREX1 11277 DDX51 317781 pd <> reg.ITFP.txt: no annot
PSMA1 5682 PSMB3 5691 pp -- int.Intact: MI:0914(association);
int.I2D: IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Yeast, YeastHigh, BioGrid_Yeast
PSMA1 5682 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastMedium
RPSA 3921 VARS 7407 pp -- int.I2D: IntAct_Yeast
PSMC3 5702 PSMD3 5709 pd < reg.ITFP.txt: no annot
PSMC3 5702 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, Krogan_NonCore, YeastHigh
PSMD3 5709 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
CLTC 1213 RUVBL1 8607 pp -- int.I2D: MINT_Worm, IntAct_Worm
EIF2S2 8894 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMD1 5707 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 RAD23B 5887 pp -- int.I2D: IntAct_Rat
PSMB2 5690 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMA1 5682 PSMA2 5683 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
RPSA 3921 RAN 5901 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
CLTC 1213 EIF2S2 8894 pp -- int.I2D: YeastLow
PSMD6 9861 RUVBL2 10856 pp -- int.I2D: YeastLow
TUBG1 7283 VARS 7407 pd < reg.ITFP.txt: no annot
CSE1L 1434 RPA1 6117 pd < reg.ITFP.txt: no annot
ACTB 60 PSMA3 5684 pp -- int.I2D: BioGrid, BioGrid_Yeast
CLTC 1213 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
RUVBL1 8607 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
RUVBL1 8607 RUVBL2 10856 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid, BioGrid_Mouse, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct, IntAct_Fly, IntAct_Worm, IntAct_Yeast, INTEROLOG, MINT_Worm, MINT_Yeast, BCI, BioGrid_Fly, BIND_Fly, BIND_Worm, FlyHigh, INNATEDB, Krogan_Core, MIPS, YeastHigh, Yu_GoldStd;
int.Ravasi: -;
int.HPRD: in vitro, in vivo, yeast 2-hybrid;
int.DIP: MI:0915(physical association)
RPSA 3921 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, BioGrid, YeastMedium
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
MTHFD1 4522 PRMT3 10196 pd < reg.ITFP.txt: no annot
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
ACTB 60 CAD 790 pp -- int.I2D: IntAct_Yeast
PSMD1 5707 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMD1 5707 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast
PSMA1 5682 RPA1 6117 pd < reg.ITFP.txt: no annot
PSMB7 5695 RBX1 9978 pd < reg.ITFP.txt: no annot
PSMA3 5684 RUVBL2 10856 pp -- int.I2D: YeastLow
CAD 790 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA2 5683 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast, YeastLow
HNRNPC 3183 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMD3 5709 RUVBL2 10856 pp -- int.I2D: YeastLow
VARS 7407 POLE4 56655 pd <> reg.ITFP.txt: no annot
PSMA2 5683 PSMB3 5691 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd
PSMD3 5709 TUBG1 7283 pd > reg.ITFP.txt: no annot
PSMD11 5717 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, IntAct, INTEROLOG
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
CAD 790 DDX51 317781 pp -- int.I2D: IntAct_Yeast
CAD 790 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast
VARS 7407 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
HNRNPC 3183 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMA5 5686 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastHigh, Yu_GoldStd, Krogan_Core, MINT_Yeast
CSE1L 1434 RPSA 3921 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA2 5683 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMC3 5702 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastHigh, BioGrid, IntAct_Yeast, Krogan_Core, MINT_Yeast
PSMB1 5689 PSMB7 5695 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastLow, IntAct, Krogan_Core, MINT_Yeast, Yu_GoldStd;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
VARS 7407 RUVBL1 8607 pd <> reg.ITFP.txt: no annot
PSMA3 5684 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow
PSMD1 5707 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, IntAct, Krogan_Core
PSMA3 5684 PSMD1 5707 pp -- int.I2D: BioGrid, BioGrid_Yeast
PSMA5 5686 PSMB3 5691 pp -- int.I2D: BioGrid_Yeast, YeastHigh
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 EFTUD2 9343 pp -- int.I2D: BioGrid
PSMB2 5690 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CLTC 1213 PFN1 5216 pp -- int.I2D: BioGrid_Mouse
PSMB7 5695 DDX51 317781 pd < reg.ITFP.txt: no annot
RANGAP1 5905 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMB7 5695 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, MINT_Yeast, YeastLow, Krogan_Core
MTHFD1 4522 RUVBL1 8607 pd < reg.ITFP.txt: no annot
MTHFD1 4522 VARS 7407 pd < reg.ITFP.txt: no annot
MTHFD1 4522 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
PSMD3 5709 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, IntAct, IntAct_Yeast, MINT_Worm, MINT_Yeast, YeastHigh, BioGrid, BIND_Yeast, IntAct_Worm, INTEROLOG, Krogan_Core, MIPS
PSMC3 5702 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh
PSMA5 5686 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
TUBG1 7283 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 RUVBL1 8607 pp -- int.I2D: BioGrid
PSMB7 5695 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RAN 5901 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, NON_CORE
RAN 5901 VARS 7407 pd < reg.ITFP.txt: no annot
TUBG1 7283 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMD6 9861 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh
POLR2F 5435 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 RAN 5901 pp -- int.I2D: IntAct_Yeast
PSMB3 5691 PSMB7 5695 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, YeastHigh, HPRD, Krogan_Core, MINT_Yeast, MIPS;
int.HPRD: yeast 2-hybrid
PSMD3 5709 RANGAP1 5905 pd > reg.ITFP.txt: no annot
ACTB 60 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
MTHFD1 4522 RPA1 6117 pd < reg.ITFP.txt: no annot
VARS 7407 DDX51 317781 pd <> reg.ITFP.txt: no annot
RUVBL1 8607 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMD3 5709 VARS 7407 pd <> reg.ITFP.txt: no annot
PSMB7 5695 PSMD1 5707 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct
PSMA1 5682 PSMA3 5684 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, CE_DATA, HPRD, IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Worm, IntAct_Yeast, MINT_Worm, BioGrid, BioGrid_Fly, BIND_Fly, BIND_Yeast, FlyHigh, Krogan_Core, MINT_Fly, MINT_Yeast, YeastHigh, Yu_GoldStd;
int.HPRD: in vitro
PSMB7 5695 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMA2 5683 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMC3 5702 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast
PSMA1 5682 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMD11 5717 TUBG1 7283 pd > reg.ITFP.txt: no annot
ACTB 60 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMC3 5702 PSMD11 5717 pd < reg.ITFP.txt: no annot
PSMC3 5702 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh
RPSA 3921 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA1 5682 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RAD23B 5887 pp -- int.I2D: IntAct_Rat
PSMC3 5702 RAD23B 5887 pp -- int.I2D: BioGrid_Yeast, IntAct_Rat, Krogan_Core, MINT_Yeast
PSMB2 5690 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, INTEROLOG, MINT, Yu_GoldStd, BCI, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
ACTB 60 RPA2 6118 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMB1 5689 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
MTHFD1 4522 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMA5 5686 POLE4 56655 pd < reg.ITFP.txt: no annot
CAD 790 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 DDX51 317781 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct
ACTB 60 PFN1 5216 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Mouse, HPRD, MINT_Mouse, BCI, IntAct;
int.HPRD: in vitro;
int.DIP: MI:0407(direct interaction)
PSMD11 5717 EFTUD2 9343 pd > reg.ITFP.txt: no annot
RUVBL1 8607 PSMD6 9861 pp -- int.I2D: YeastLow
PSMA3 5684 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast, BioGrid, YeastLow
ACTB 60 CDC16 8881 pp -- int.I2D: YeastLow
PSMD11 5717 RUVBL2 10856 pp -- int.I2D: YeastLow
RPA1 6117 RPA2 6118 pp -- int.Intact: MI:0407(direct interaction), MI:0915(physical association);
int.I2D: HPRD, BCI, BioGrid, BIND, IntAct;
int.Transfac: -;
int.HPRD: in vitro, in vivo
CAD 790 RANGAP1 5905 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMB3 5691 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMB1 5689 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, IntAct_Yeast, YeastHigh
VARS 7407 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
PSMA5 5686 PSMB1 5689 pp -- int.I2D: BioGrid_Yeast, BIND_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd
RANGAP1 5905 VARS 7407 pd < reg.ITFP.txt: no annot
RAN 5901 RANGAP1 5905 pp -- int.I2D: BioGrid, BioGrid_Fly, BioGrid_Yeast, HPRD, IntAct_Yeast, MINT_Yeast, BCI, YeastLow;
int.HPRD: in vitro
PSMB1 5689 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMD1 5707 RUVBL2 10856 pp -- int.I2D: IntAct_Yeast
PSMA3 5684 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMB2 5690 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMA3 5684 PSMA5 5686 pp -- int.I2D: BioGrid_Yeast, BIND_Yeast, IntAct_Mouse, IntAct_Yeast, MINT_Yeast, YeastHigh, Krogan_Core, Tarassov_PCA
PSMB1 5689 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMA5 5686 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast
ACTB 60 CSE1L 1434 pp -- int.I2D: IntAct_Yeast
PSMA3 5684 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB2 5690 PSMD11 5717 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB2 5690 VARS 7407 pd < reg.ITFP.txt: no annot
EIF6 3692 PSMB1 5689 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMA2 5683 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow, BioGrid
PSMB3 5691 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastLow
PSMA2 5683 PSMB1 5689 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, BCI, BioGrid, IntAct, YeastHigh
RPSA 3921 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RPA1 6117 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMD14 10213 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB3 5691 PSMD11 5717 pp -- int.I2D: YeastLow
PSMD3 5709 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, INTEROLOG, MINT_Yeast, Krogan_Core, YeastHigh
PSMB7 5695 RPA1 6117 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, MINT_Yeast, IntAct_Yeast, Krogan_Core, YeastHigh
CCNA2 890 RPA1 6117 pp -- int.I2D: BioGrid
EIF6 3692 DDX51 317781 pd < reg.ITFP.txt: no annot
EIF6 3692 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RAN 5901 TREX1 11277 pd < reg.ITFP.txt: no annot
RUVBL2 10856 TREX1 11277 pd <> reg.ITFP.txt: no annot
PSMB2 5690 RAD23B 5887 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, BIND_Yeast, MINT_Yeast, MIPS
RAD23B 5887 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast
ACTB 60 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid
CAD 790 RPSA 3921 pp -- int.I2D: IntAct_Yeast
PSMA2 5683 PSMA3 5684 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BIND_Yeast, HPRD;
int.HPRD: yeast 2-hybrid
PSMA3 5684 PSMB3 5691 pp -- int.I2D: BioGrid_Yeast, IntAct_Fly, IntAct_Yeast, YeastHigh
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
POLR2F 5435 VARS 7407 pd < reg.ITFP.txt: no annot
PSMD11 5717 EIF2S2 8894 pd > reg.ITFP.txt: no annot
ACTB 60 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB2 5690 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core
EIF6 3692 RUVBL1 8607 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct

Related GO terms (443)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0000502proteasome complex2.33e-273.80e-236.651152258
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.60e-262.62e-226.487152465
GO:0006521regulation of cellular amino acid metabolic process4.31e-267.04e-226.766142150
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle5.54e-269.04e-226.380152470
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.39e-252.27e-216.300152474
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process4.08e-256.66e-216.205152579
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest2.74e-244.47e-206.387142265
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent1.64e-232.67e-196.220142373
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I3.70e-236.03e-196.143142377
GO:0000082G1/S transition of mitotic cell cycle1.55e-222.53e-185.3731633150
GO:0005654nucleoplasm5.73e-229.35e-183.26027831095
GO:0002474antigen processing and presentation of peptide antigen via MHC class I7.46e-221.22e-175.855142394
GO:0000278mitotic cell cycle1.08e-211.77e-174.2872052398
GO:0000209protein polyubiquitination1.67e-202.73e-165.5511421116
GO:0042981regulation of apoptotic process7.71e-191.26e-145.1711426151
GO:0010467gene expression1.30e-182.11e-143.6092158669
GO:0016071mRNA metabolic process4.79e-187.82e-144.7081534223
GO:0034641cellular nitrogen compound metabolic process7.51e-181.23e-134.9421425177
GO:0016070RNA metabolic process2.24e-173.66e-134.5611534247
GO:0005839proteasome core complex4.07e-176.64e-137.43281118
GO:0005829cytosol7.19e-171.17e-122.233311252562
GO:0004298threonine-type endopeptidase activity1.17e-161.90e-127.28081120
GO:0016032viral process2.89e-164.72e-123.6951855540
GO:0043066negative regulation of apoptotic process1.87e-123.04e-083.6511430433
GO:0022624proteasome accessory complex2.42e-123.96e-087.1006917
GO:0006915apoptotic process4.95e-128.07e-083.3521534571
GO:0070062extracellular vesicular exosome7.75e-111.27e-061.94925982516
GO:0019773proteasome core complex, alpha-subunit complex2.63e-094.29e-057.602458
GO:0044281small molecule metabolic process6.65e-091.09e-042.35117571295
GO:0016020membrane8.76e-081.43e-032.00218801746
GO:0005634nucleus1.43e-072.33e-031.223291314828
GO:0006281DNA repair3.09e-075.04e-033.558822264
GO:0005730nucleolus3.21e-075.25e-031.97217701684
GO:0005515protein binding3.78e-076.18e-031.021321726127
GO:0005838proteasome regulatory particle3.43e-065.60e-026.6023712
GO:0035267NuA4 histone acetyltransferase complex5.66e-069.23e-026.3803414
GO:0003684damaged DNA binding8.67e-061.42e-014.93041151
GO:0006298mismatch repair1.75e-052.86e-015.8653620
GO:0000718nucleotide-excision repair, DNA damage removal2.04e-053.33e-015.7953521
GO:0006310DNA recombination2.58e-054.21e-014.5364467
GO:0006289nucleotide-excision repair2.90e-054.73e-014.49441269
GO:0003697single-stranded DNA binding2.90e-054.73e-014.4944969
GO:0000730DNA recombinase assembly6.43e-051.00e+007.280235
GO:0000812Swr1 complex1.79e-041.00e+006.602238
GO:0006283transcription-coupled nucleotide-excision repair2.23e-041.00e+004.6643846
GO:0007067mitotic nuclear division3.02e-041.00e+003.072513231
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding3.59e-041.00e+004.4323554
GO:0043968histone H2A acetylation4.20e-041.00e+006.0172312
GO:0000724double-strand break repair via homologous recombination4.21e-041.00e+004.3543657
GO:0005662DNA replication factor A complex4.95e-041.00e+005.9022313
GO:0030234enzyme regulator activity4.95e-041.00e+005.9022313
GO:0016887ATPase activity5.01e-041.00e+003.43247144
GO:0031011Ino80 complex5.77e-041.00e+005.7952314
GO:0042176regulation of protein catabolic process7.58e-041.00e+005.6022316
GO:0006259DNA metabolic process1.08e-031.00e+005.3542319
GO:0003678DNA helicase activity1.08e-031.00e+005.3542319
GO:0006297nucleotide-excision repair, DNA gap filling1.45e-031.00e+005.1432522
GO:0032201telomere maintenance via semi-conservative replication1.45e-031.00e+005.1432722
GO:0043044ATP-dependent chromatin remodeling1.58e-031.00e+005.0792423
GO:0016363nuclear matrix1.70e-031.00e+003.66431192
GO:0006611protein export from nucleus1.87e-031.00e+004.9582425
GO:0000722telomere maintenance via recombination2.02e-031.00e+004.9022726
GO:0071339MLL1 complex2.18e-031.00e+004.8472327
GO:0043022ribosome binding2.34e-031.00e+004.7952328
GO:0043967histone H4 acetylation2.34e-031.00e+004.7952328
GO:0031492nucleosomal DNA binding2.34e-031.00e+004.7952428
GO:0005737cytoplasm2.47e-031.00e+000.89319983976
GO:0004088carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity2.57e-031.00e+008.602111
GO:0070335aspartate binding2.57e-031.00e+008.602111
GO:0008262importin-alpha export receptor activity2.57e-031.00e+008.602111
GO:0008541proteasome regulatory particle, lid subcomplex2.57e-031.00e+008.602111
GO:0032558adenyl deoxyribonucleotide binding2.57e-031.00e+008.602111
GO:0004151dihydroorotase activity2.57e-031.00e+008.602111
GO:0000054ribosomal subunit export from nucleus2.57e-031.00e+008.602111
GO:0004070aspartate carbamoyltransferase activity2.57e-031.00e+008.602111
GO:0005098Ran GTPase activator activity2.57e-031.00e+008.602111
GO:0004486methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity2.57e-031.00e+008.602111
GO:0006271DNA strand elongation involved in DNA replication2.87e-031.00e+004.6482931
GO:0030529ribonucleoprotein complex3.12e-031.00e+003.35438114
GO:0006325chromatin organization3.87e-031.00e+003.24534123
GO:0006260DNA replication4.05e-031.00e+003.221312125
GO:0006284base-excision repair4.51e-031.00e+004.3172739
GO:0006413translational initiation4.62e-031.00e+003.154312131
GO:0004832valine-tRNA ligase activity5.14e-031.00e+007.602112
GO:0051054positive regulation of DNA metabolic process5.14e-031.00e+007.602112
GO:0002176male germ cell proliferation5.14e-031.00e+007.602112
GO:0000715nucleotide-excision repair, DNA damage recognition5.14e-031.00e+007.602112
GO:0006407rRNA export from nucleus5.14e-031.00e+007.602112
GO:0006438valyl-tRNA aminoacylation5.14e-031.00e+007.602112
GO:0000105histidine biosynthetic process5.14e-031.00e+007.602112
GO:00082963'-5'-exodeoxyribonuclease activity5.14e-031.00e+007.602112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)5.14e-031.00e+007.602112
GO:0005055laminin receptor activity5.14e-031.00e+007.602112
GO:0070409carbamoyl phosphate biosynthetic process5.14e-031.00e+007.602112
GO:0032508DNA duplex unwinding5.21e-031.00e+004.2102442
GO:0044822poly(A) RNA binding5.57e-031.00e+001.5288501078
GO:0050434positive regulation of viral transcription5.71e-031.00e+004.1432544
GO:0003743translation initiation factor activity7.04e-031.00e+003.9872449
GO:0043234protein complex7.23e-031.00e+002.373417300
GO:0031100organ regeneration7.32e-031.00e+003.9582450
GO:0006200ATP catabolic process7.49e-031.00e+002.359414303
GO:0040008regulation of growth7.61e-031.00e+003.9302351
GO:0071899negative regulation of estrogen receptor binding7.70e-031.00e+007.017113
GO:0005850eukaryotic translation initiation factor 2 complex7.70e-031.00e+007.017113
GO:1900126negative regulation of hyaluronan biosynthetic process7.70e-031.00e+007.017113
GO:0071733transcriptional activation by promoter-enhancer looping7.70e-031.00e+007.017113
GO:0000056ribosomal small subunit export from nucleus7.70e-031.00e+007.017113
GO:0044205'de novo' UMP biosynthetic process7.70e-031.00e+007.017113
GO:0006207'de novo' pyrimidine nucleobase biosynthetic process7.70e-031.00e+007.017113
GO:0071439clathrin complex7.70e-031.00e+007.017113
GO:0071942XPC complex7.70e-031.00e+007.017113
GO:0000398mRNA splicing, via spliceosome8.73e-031.00e+002.821312165
GO:0000932cytoplasmic mRNA processing body9.12e-031.00e+003.7952356
GO:0000723telomere maintenance1.01e-021.00e+003.7192859
GO:0005643nuclear pore1.01e-021.00e+003.7192459
GO:0000774adenyl-nucleotide exchange factor activity1.03e-021.00e+006.602114
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)1.03e-021.00e+006.602114
GO:0000212meiotic spindle organization1.03e-021.00e+006.602114
GO:003068690S preribosome1.03e-021.00e+006.602114
GO:0032051clathrin light chain binding1.03e-021.00e+006.602114
GO:0019788NEDD8 ligase activity1.03e-021.00e+006.602114
GO:0016274protein-arginine N-methyltransferase activity1.03e-021.00e+006.602114
GO:0004488methylenetetrahydrofolate dehydrogenase (NADP+) activity1.03e-021.00e+006.602114
GO:0004329formate-tetrahydrofolate ligase activity1.03e-021.00e+006.602114
GO:0043141ATP-dependent 5'-3' DNA helicase activity1.03e-021.00e+006.602114
GO:0034969histone arginine methylation1.03e-021.00e+006.602114
GO:0006543glutamine catabolic process1.03e-021.00e+006.602114
GO:0009396folic acid-containing compound biosynthetic process1.03e-021.00e+006.602114
GO:0004477methenyltetrahydrofolate cyclohydrolase activity1.03e-021.00e+006.602114
GO:0031467Cul7-RING ubiquitin ligase complex1.03e-021.00e+006.602114
GO:0000055ribosomal large subunit export from nucleus1.03e-021.00e+006.602114
GO:0008853exodeoxyribonuclease III activity1.03e-021.00e+006.602114
GO:0032232negative regulation of actin filament bundle assembly1.03e-021.00e+006.602114
GO:1903077negative regulation of protein localization to plasma membrane1.03e-021.00e+006.602114
GO:0032481positive regulation of type I interferon production1.07e-021.00e+003.6712661
GO:0006302double-strand break repair1.11e-021.00e+003.6482862
GO:0051414response to cortisol1.28e-021.00e+006.280115
GO:1900029positive regulation of ruffle assembly1.28e-021.00e+006.280115
GO:0031465Cul4B-RING E3 ubiquitin ligase complex1.28e-021.00e+006.280125
GO:0042256mature ribosome assembly1.28e-021.00e+006.280115
GO:0001940male pronucleus1.28e-021.00e+006.280115
GO:0009086methionine biosynthetic process1.28e-021.00e+006.280115
GO:0032407MutSalpha complex binding1.28e-021.00e+006.280115
GO:2000001regulation of DNA damage checkpoint1.28e-021.00e+006.280115
GO:0008622epsilon DNA polymerase complex1.28e-021.00e+006.280115
GO:0031461cullin-RING ubiquitin ligase complex1.28e-021.00e+006.280115
GO:0071169establishment of protein localization to chromatin1.28e-021.00e+006.280115
GO:0043248proteasome assembly1.28e-021.00e+006.280115
GO:0030891VCB complex1.28e-021.00e+006.280125
GO:0005827polar microtubule1.28e-021.00e+006.280115
GO:0005638lamin filament1.28e-021.00e+006.280115
GO:0061133endopeptidase activator activity1.28e-021.00e+006.280115
GO:0003924GTPase activity1.52e-021.00e+002.52239203
GO:0030130clathrin coat of trans-Golgi network vesicle1.53e-021.00e+006.017116
GO:0030118clathrin coat1.53e-021.00e+006.017116
GO:0043023ribosomal large subunit binding1.53e-021.00e+006.017126
GO:0031466Cul5-RING ubiquitin ligase complex1.53e-021.00e+006.017116
GO:0030957Tat protein binding1.53e-021.00e+006.017146
GO:0046134pyrimidine nucleoside biosynthetic process1.53e-021.00e+006.017116
GO:0032405MutLalpha complex binding1.53e-021.00e+006.017126
GO:0032853positive regulation of Ran GTPase activity1.53e-021.00e+006.017116
GO:0008469histone-arginine N-methyltransferase activity1.53e-021.00e+006.017116
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process1.63e-021.00e+003.3542376
GO:0071013catalytic step 2 spliceosome1.76e-021.00e+003.2982779
GO:0010950positive regulation of endopeptidase activity1.79e-021.00e+005.795117
GO:0000028ribosomal small subunit assembly1.79e-021.00e+005.795117
GO:0002161aminoacyl-tRNA editing activity1.79e-021.00e+005.795127
GO:0035242protein-arginine omega-N asymmetric methyltransferase activity1.79e-021.00e+005.795117
GO:0001939female pronucleus1.79e-021.00e+005.795117
GO:0031462Cul2-RING ubiquitin ligase complex1.79e-021.00e+005.795127
GO:0030132clathrin coat of coated pit1.79e-021.00e+005.795117
GO:0035999tetrahydrofolate interconversion1.79e-021.00e+005.795117
GO:0072341modified amino acid binding1.79e-021.00e+005.795117
GO:0000930gamma-tubulin complex1.79e-021.00e+005.795117
GO:0046826negative regulation of protein export from nucleus1.79e-021.00e+005.795117
GO:0019919peptidyl-arginine methylation, to asymmetrical-dimethyl arginine1.79e-021.00e+005.795117
GO:0006184GTP catabolic process1.89e-021.00e+002.40639220
GO:0005681spliceosomal complex1.93e-021.00e+003.2272383
GO:0031464Cul4A-RING E3 ubiquitin ligase complex2.04e-021.00e+005.602128
GO:0001055RNA polymerase II activity2.04e-021.00e+005.602138
GO:0070688MLL5-L complex2.04e-021.00e+005.602118
GO:0045116protein neddylation2.04e-021.00e+005.602128
GO:0000800lateral element2.04e-021.00e+005.602118
GO:0006164purine nucleotide biosynthetic process2.04e-021.00e+005.602128
GO:0005524ATP binding2.05e-021.00e+001.1998461354
GO:0008380RNA splicing2.17e-021.00e+002.329313232
GO:0014075response to amine2.29e-021.00e+005.432119
GO:0006228UTP biosynthetic process2.29e-021.00e+005.432119
GO:0030837negative regulation of actin filament polymerization2.29e-021.00e+005.432119
GO:0032434regulation of proteasomal ubiquitin-dependent protein catabolic process2.29e-021.00e+005.432119
GO:0010389regulation of G2/M transition of mitotic cell cycle2.29e-021.00e+005.432119
GO:0031000response to caffeine2.29e-021.00e+005.432129
GO:0016605PML body2.34e-021.00e+003.0792592
GO:0042470melanosome2.34e-021.00e+003.07921092
GO:0005200structural constituent of cytoskeleton2.39e-021.00e+003.0632793
GO:0001649osteoblast differentiation2.48e-021.00e+003.0322695
GO:0070628proteasome binding2.54e-021.00e+005.2801110
GO:0046655folic acid metabolic process2.54e-021.00e+005.2801110
GO:0006450regulation of translational fidelity2.54e-021.00e+005.2801210
GO:0051497negative regulation of stress fiber assembly2.54e-021.00e+005.2801110
GO:0010569regulation of double-strand break repair via homologous recombination2.80e-021.00e+005.1431111
GO:0031571mitotic G1 DNA damage checkpoint2.80e-021.00e+005.1431311
GO:0001054RNA polymerase I activity2.80e-021.00e+005.1431311
GO:0045120pronucleus2.80e-021.00e+005.1431111
GO:0033762response to glucagon2.80e-021.00e+005.1431111
GO:0035458cellular response to interferon-beta2.80e-021.00e+005.1431211
GO:0061136regulation of proteasomal protein catabolic process3.05e-021.00e+005.0171112
GO:00709353'-UTR-mediated mRNA stabilization3.05e-021.00e+005.0171212
GO:0005736DNA-directed RNA polymerase I complex3.05e-021.00e+005.0171312
GO:0042273ribosomal large subunit biogenesis3.30e-021.00e+004.9021413
GO:0032479regulation of type I interferon production3.30e-021.00e+004.9021213
GO:0000738DNA catabolic process, exonucleolytic3.30e-021.00e+004.9021213
GO:0008266poly(U) RNA binding3.30e-021.00e+004.9021113
GO:0005819spindle3.47e-021.00e+002.76927114
GO:0019058viral life cycle3.53e-021.00e+002.757210115
GO:0007020microtubule nucleation3.54e-021.00e+004.7951114
GO:0007095mitotic G2 DNA damage checkpoint3.54e-021.00e+004.7951114
GO:0072562blood microparticle3.58e-021.00e+002.74424116
GO:0035066positive regulation of histone acetylation3.79e-021.00e+004.6951115
GO:0005671Ada2/Gcn5/Ada3 transcription activator complex3.79e-021.00e+004.6951115
GO:0006261DNA-dependent DNA replication3.79e-021.00e+004.6951215
GO:0005665DNA-directed RNA polymerase II, core complex4.04e-021.00e+004.6021416
GO:0050998nitric-oxide synthase binding4.04e-021.00e+004.6021116
GO:0001673male germ cell nucleus4.04e-021.00e+004.6021116
GO:0001056RNA polymerase III activity4.04e-021.00e+004.6021316
GO:00084083'-5' exonuclease activity4.04e-021.00e+004.6021216
GO:0006511ubiquitin-dependent protein catabolic process4.23e-021.00e+002.61325127
GO:0010243response to organonitrogen compound4.29e-021.00e+004.5151217
GO:0005666DNA-directed RNA polymerase III complex4.29e-021.00e+004.5151317
GO:0075733intracellular transport of virus4.29e-021.00e+004.5151217
GO:0007126meiotic nuclear division4.29e-021.00e+004.5151117
GO:0070536protein K63-linked deubiquitination4.53e-021.00e+004.4321118
GO:0006386termination of RNA polymerase III transcription4.53e-021.00e+004.4321318
GO:0071392cellular response to estradiol stimulus4.53e-021.00e+004.4321118
GO:0006541glutamine metabolic process4.53e-021.00e+004.4321118
GO:0070064proline-rich region binding4.53e-021.00e+004.4321218
GO:0031122cytoplasmic microtubule organization4.53e-021.00e+004.4321218
GO:0035861site of double-strand break4.53e-021.00e+004.4321118
GO:0006385transcription elongation from RNA polymerase III promoter4.53e-021.00e+004.4321318
GO:0006303double-strand break repair via nonhomologous end joining4.53e-021.00e+004.4321318
GO:0000790nuclear chromatin4.59e-021.00e+002.54727133
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process4.78e-021.00e+004.3541119
GO:0048863stem cell differentiation4.78e-021.00e+004.3541119
GO:0007088regulation of mitosis4.78e-021.00e+004.3541119
GO:1903506regulation of nucleic acid-templated transcription4.78e-021.00e+004.3541119
GO:0000086G2/M transition of mitotic cell cycle4.84e-021.00e+002.50427137
GO:0019901protein kinase binding4.89e-021.00e+001.865321320
GO:0048873homeostasis of number of cells within a tissue5.03e-021.00e+004.2801120
GO:0005680anaphase-promoting complex5.03e-021.00e+004.2801420
GO:0005719nuclear euchromatin5.03e-021.00e+004.2801220
GO:0005525GTP binding5.19e-021.00e+001.830311328
GO:0071364cellular response to epidermal growth factor stimulus5.27e-021.00e+004.2101121
GO:0061024membrane organization5.42e-021.00e+002.41225146
GO:0033574response to testosterone5.51e-021.00e+004.1431222
GO:0030863cortical cytoskeleton5.51e-021.00e+004.1431122
GO:0036464cytoplasmic ribonucleoprotein granule5.51e-021.00e+004.1431422
GO:0007052mitotic spindle organization5.51e-021.00e+004.1431222
GO:0006457protein folding5.62e-021.00e+002.38328149
GO:0005813centrosome5.63e-021.00e+001.782312339
GO:0031593polyubiquitin binding5.76e-021.00e+004.0791123
GO:0031463Cul3-RING ubiquitin ligase complex5.76e-021.00e+004.0791223
GO:0043236laminin binding5.76e-021.00e+004.0791123
GO:0006513protein monoubiquitination5.76e-021.00e+004.0791123
GO:0008135translation factor activity, nucleic acid binding6.00e-021.00e+004.0171424
GO:0010634positive regulation of epithelial cell migration6.00e-021.00e+004.0171124
GO:0000794condensed nuclear chromosome6.00e-021.00e+004.0171224
GO:0006206pyrimidine nucleobase metabolic process6.00e-021.00e+004.0171224
GO:0032781positive regulation of ATPase activity6.24e-021.00e+003.9581125
GO:0008536Ran GTPase binding6.24e-021.00e+003.9581225
GO:0005844polysome6.24e-021.00e+003.9581425
GO:0017144drug metabolic process6.24e-021.00e+003.9581125
GO:0003723RNA binding6.29e-021.00e+001.715319355
GO:0070979protein K11-linked ubiquitination6.48e-021.00e+003.9021326
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia6.48e-021.00e+003.9021226
GO:0006730one-carbon metabolic process6.48e-021.00e+003.9021126
GO:0004003ATP-dependent DNA helicase activity6.73e-021.00e+003.8471327
GO:0034080CENP-A containing nucleosome assembly6.73e-021.00e+003.8471227
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding6.94e-021.00e+002.21025168
GO:0005925focal adhesion6.94e-021.00e+001.656318370
GO:0019894kinesin binding6.97e-021.00e+003.7951128
GO:0019005SCF ubiquitin ligase complex7.21e-021.00e+003.7441129
GO:0003730mRNA 3'-UTR binding7.21e-021.00e+003.7441229
GO:0003887DNA-directed DNA polymerase activity7.21e-021.00e+003.7441329
GO:0030669clathrin-coated endocytic vesicle membrane7.21e-021.00e+003.7441129
GO:0071897DNA biosynthetic process7.21e-021.00e+003.7441229
GO:00063707-methylguanosine mRNA capping7.45e-021.00e+003.6951430
GO:0006360transcription from RNA polymerase I promoter7.45e-021.00e+003.6951430
GO:0017048Rho GTPase binding7.68e-021.00e+003.6481131
GO:0031623receptor internalization7.68e-021.00e+003.6481131
GO:0007094mitotic spindle assembly checkpoint7.68e-021.00e+003.6481531
GO:0031625ubiquitin protein ligase binding7.82e-021.00e+002.110213180
GO:0031397negative regulation of protein ubiquitination7.92e-021.00e+003.6021132
GO:0034644cellular response to UV7.92e-021.00e+003.6021532
GO:0033572transferrin transport7.92e-021.00e+003.6021632
GO:1903507negative regulation of nucleic acid-templated transcription7.92e-021.00e+003.6021232
GO:0015629actin cytoskeleton8.04e-021.00e+002.08625183
GO:0005876spindle microtubule8.40e-021.00e+003.5151334
GO:0032588trans-Golgi network membrane8.87e-021.00e+003.4321136
GO:0034332adherens junction organization8.87e-021.00e+003.4321136
GO:0004221ubiquitin thiolesterase activity8.87e-021.00e+003.4321236
GO:0001895retina homeostasis8.87e-021.00e+003.4321136
GO:0030838positive regulation of actin filament polymerization8.87e-021.00e+003.4321236
GO:0051084'de novo' posttranslational protein folding9.10e-021.00e+003.3931437
GO:0018107peptidyl-threonine phosphorylation9.10e-021.00e+003.3931137
GO:0070527platelet aggregation9.34e-021.00e+003.3541238
GO:0050681androgen receptor binding9.34e-021.00e+003.3541438
GO:0006383transcription from RNA polymerase III promoter9.57e-021.00e+003.3171339
GO:0008026ATP-dependent helicase activity9.57e-021.00e+003.3171339
GO:0031490chromatin DNA binding9.57e-021.00e+003.3171239
GO:0051496positive regulation of stress fiber assembly9.57e-021.00e+003.3171239
GO:0022627cytosolic small ribosomal subunit9.57e-021.00e+003.3171339
GO:0032092positive regulation of protein binding9.57e-021.00e+003.3171339
GO:0007595lactation9.57e-021.00e+003.3171239
GO:0000781chromosome, telomeric region9.80e-021.00e+003.2801240
GO:0043195terminal bouton1.00e-011.00e+003.2451141
GO:0005546phosphatidylinositol-4,5-bisphosphate binding1.00e-011.00e+003.2451241
GO:0030521androgen receptor signaling pathway1.00e-011.00e+003.2451241
GO:0001701in utero embryonic development1.02e-011.00e+001.88826210
GO:0006418tRNA aminoacylation for protein translation1.03e-011.00e+003.2101542
GO:0071363cellular response to growth factor stimulus1.03e-011.00e+003.2101242
GO:0014070response to organic cyclic compound1.05e-011.00e+003.1761343
GO:0048146positive regulation of fibroblast proliferation1.07e-011.00e+003.1431244
GO:0007286spermatid development1.07e-011.00e+003.1431144
GO:0006892post-Golgi vesicle-mediated transport1.07e-011.00e+003.1431244
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding1.07e-011.00e+003.1431244
GO:0015030Cajal body1.10e-011.00e+003.1101245
GO:0043966histone H3 acetylation1.10e-011.00e+003.1101245
GO:0021762substantia nigra development1.12e-011.00e+003.0791146
GO:0030136clathrin-coated vesicle1.12e-011.00e+003.0791146
GO:0000079regulation of cyclin-dependent protein serine/threonine kinase activity1.14e-011.00e+003.0481347
GO:0019003GDP binding1.16e-011.00e+003.0171248
GO:0035690cellular response to drug1.21e-011.00e+002.9581250
GO:0006412translation1.22e-011.00e+001.726215235
GO:0008168methyltransferase activity1.26e-011.00e+002.9021152
GO:0003713transcription coactivator activity1.26e-011.00e+001.701210239
GO:0003725double-stranded RNA binding1.30e-011.00e+002.8471654
GO:0090305nucleic acid phosphodiester bond hydrolysis1.30e-011.00e+002.8471254
GO:0000226microtubule cytoskeleton organization1.32e-011.00e+002.8211355
GO:0042802identical protein binding1.32e-011.00e+001.248318491
GO:0044267cellular protein metabolic process1.34e-011.00e+001.236324495
GO:0030097hemopoiesis1.39e-011.00e+002.7441358
GO:0008237metallopeptidase activity1.39e-011.00e+002.7441158
GO:0005840ribosome1.41e-011.00e+002.7191259
GO:0045216cell-cell junction organization1.41e-011.00e+002.7191259
GO:0019903protein phosphatase binding1.50e-011.00e+002.6251463
GO:0000776kinetochore1.50e-011.00e+002.6251463
GO:0042995cell projection1.50e-011.00e+002.6251663
GO:0007283spermatogenesis1.58e-011.00e+001.49426276
GO:0006368transcription elongation from RNA polymerase II promoter1.59e-011.00e+002.5361667
GO:0006338chromatin remodeling1.61e-011.00e+002.5151468
GO:0000777condensed chromosome kinetochore1.61e-011.00e+002.5151268
GO:0034329cell junction assembly1.68e-011.00e+002.4521171
GO:0019899enzyme binding1.69e-011.00e+001.432211288
GO:0032355response to estradiol1.72e-011.00e+002.4121573
GO:0000785chromatin1.72e-011.00e+002.4121573
GO:0055086nucleobase-containing small molecule metabolic process1.72e-011.00e+002.4121573
GO:0006767water-soluble vitamin metabolic process1.76e-011.00e+002.3731375
GO:0001843neural tube closure1.76e-011.00e+002.3731275
GO:0007265Ras protein signal transduction1.76e-011.00e+002.3731375
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis1.80e-011.00e+002.3351577
GO:0008584male gonad development1.80e-011.00e+002.3351277
GO:0006766vitamin metabolic process1.82e-011.00e+002.3171378
GO:0006334nucleosome assembly1.85e-011.00e+002.2981479
GO:0007565female pregnancy1.87e-011.00e+002.2801280
GO:0019083viral transcription1.89e-011.00e+002.2621881
GO:0002576platelet degranulation1.91e-011.00e+002.2451482
GO:0001889liver development1.91e-011.00e+002.2451382
GO:0005856cytoskeleton1.91e-011.00e+001.32128311
GO:0047485protein N-terminus binding1.99e-011.00e+002.1761486
GO:0006898receptor-mediated endocytosis1.99e-011.00e+002.1761286
GO:0006415translational termination2.01e-011.00e+002.1591887
GO:0008283cell proliferation2.09e-011.00e+001.231212331
GO:0000922spindle pole2.10e-011.00e+002.0941491
GO:0003690double-stranded DNA binding2.10e-011.00e+002.0941491
GO:0045087innate immune response2.11e-011.00e+000.920320616
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II2.12e-011.00e+002.0791492
GO:0003682chromatin binding2.12e-011.00e+001.218212334
GO:0006928cellular component movement2.12e-011.00e+002.0791792
GO:0006414translational elongation2.14e-011.00e+002.06311193
GO:0051082unfolded protein binding2.18e-011.00e+002.0321695
GO:0006364rRNA processing2.20e-011.00e+002.0171596
GO:0071456cellular response to hypoxia2.24e-011.00e+001.9871498
GO:0006614SRP-dependent cotranslational protein targeting to membrane2.36e-011.00e+001.90218104
GO:0014069postsynaptic density2.40e-011.00e+001.87411106
GO:0005815microtubule organizing center2.48e-011.00e+001.82114110
GO:0015630microtubule cytoskeleton2.51e-011.00e+001.79515112
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay2.55e-011.00e+001.769110114
GO:0005635nuclear envelope2.59e-011.00e+001.74416116
GO:0007219Notch signaling pathway2.76e-011.00e+001.63614125
GO:0030036actin cytoskeleton organization2.84e-011.00e+001.59115129
GO:0009615response to virus2.89e-011.00e+001.55816132
GO:0031982vesicle2.93e-011.00e+001.536110134
GO:0045202synapse3.04e-011.00e+001.47313140
GO:0003735structural constituent of ribosome3.06e-011.00e+001.46318141
GO:0007507heart development3.06e-011.00e+001.46315141
GO:0046872metal ion binding3.24e-011.00e+000.4075241465
GO:0046777protein autophosphorylation3.36e-011.00e+001.29813158
GO:0007596blood coagulation3.36e-011.00e+000.744214464
GO:0005198structural molecule activity3.37e-011.00e+001.28914159
GO:0043005neuron projection3.41e-011.00e+001.27114161
GO:0006397mRNA processing3.54e-011.00e+001.20113169
GO:0045893positive regulation of transcription, DNA-templated3.58e-011.00e+000.674217487
GO:0030424axon3.60e-011.00e+001.17613172
GO:0006886intracellular protein transport3.61e-011.00e+001.16714173
GO:0016607nuclear speck3.65e-011.00e+001.15114175
GO:0031965nuclear membrane3.66e-011.00e+001.14314176
GO:0004672protein kinase activity3.69e-011.00e+001.12612178
GO:0003714transcription corepressor activity3.71e-011.00e+001.11817179
GO:0019904protein domain specific binding3.74e-011.00e+001.10216181
GO:0006367transcription initiation from RNA polymerase II promoter3.79e-011.00e+001.07918184
GO:0032403protein complex binding3.81e-011.00e+001.07117185
GO:0030168platelet activation4.12e-011.00e+000.92319205
GO:0005622intracellular4.44e-011.00e+000.78215226
GO:0043025neuronal cell body4.83e-011.00e+000.61314254
GO:0004842ubiquitin-protein transferase activity4.86e-011.00e+000.60214256
GO:0005102receptor binding5.02e-011.00e+000.53615268
GO:0005794Golgi apparatus5.03e-011.00e+000.258214650
GO:0000166nucleotide binding5.07e-011.00e+000.51516272
GO:0005739mitochondrion5.10e-011.00e+000.1563241046
GO:0003779actin binding5.11e-011.00e+000.49917275
GO:0006357regulation of transcription from RNA polymerase II promoter5.11e-011.00e+000.49916275
GO:0007264small GTPase mediated signal transduction5.29e-011.00e+000.42213290
GO:0016567protein ubiquitination5.40e-011.00e+000.37815299
GO:0007411axon guidance5.73e-011.00e+000.24919327
GO:0043231intracellular membrane-bounded organelle5.79e-011.00e+000.22718332
GO:0043565sequence-specific DNA binding6.14e-011.00e+000.09014365
GO:0045944positive regulation of transcription from RNA polymerase II promoter6.25e-011.00e+00-0.061219811
GO:0007155cell adhesion6.33e-011.00e+000.01718384
GO:0008284positive regulation of cell proliferation6.40e-011.00e+00-0.01318392
GO:0046982protein heterodimerization activity6.47e-011.00e+00-0.038111399
GO:0006508proteolysis6.57e-011.00e+00-0.07719410
GO:0006366transcription from RNA polymerase II promoter6.70e-011.00e+00-0.129112425
GO:0007165signal transduction7.11e-011.00e+00-0.290217950
GO:0055114oxidation-reduction process7.16e-011.00e+00-0.308111481
GO:0048471perinuclear region of cytoplasm7.46e-011.00e+00-0.429112523
GO:0008270zinc ion binding7.70e-011.00e+00-0.4572121067
GO:0042803protein homodimerization activity8.02e-011.00e+00-0.667111617
GO:0005789endoplasmic reticulum membrane8.12e-011.00e+00-0.711110636
GO:0006351transcription, DNA-templated9.25e-011.00e+00-1.0282251585
GO:0005615extracellular space9.32e-011.00e+00-1.3781171010
GO:0006355regulation of transcription, DNA-templated9.47e-011.00e+00-1.5061171104
GO:0003677DNA binding9.74e-011.00e+00-1.7981261351
GO:0005886plasma membrane9.97e-011.00e+00-1.8662382834