reg-snw-5686

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.878	1.30e-07	1.01e-03	2.15e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-5686 subnetwork

Genes (5)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
PSMA1	5682	5	0.996	0.878	29	-	Yes	-
PSMD6	9861	2	0.848	0.878	12	TF	Yes	-
RBX1	9978	8	1.185	0.934	9	TF	Yes	-
[ PSMA5 ]	5686	1	0.378	0.878	33	-	-	-
PSMB7	5695	10	0.982	0.934	33	-	Yes	-

Interactions (4)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PSMA1	5682	PSMD6	9861	pd	<	reg.ITFP.txt: no annot
PSMB7	5695	RBX1	9978	pd	<	reg.ITFP.txt: no annot
PSMA5	5686	PSMD6	9861	pd	<	reg.ITFP.txt: no annot
PSMB7	5695	PSMD6	9861	pd	<	reg.ITFP.txt: no annot

Related GO terms (63)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006521	regulation of cellular amino acid metabolic process	1.33e-09	1.30e-05	7.574	4	16	41
GO:0000502	proteasome complex	2.35e-09	2.29e-05	7.377	4	17	47
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.56e-09	3.48e-05	7.231	4	17	52
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	3.85e-09	3.76e-05	7.204	4	17	53
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.83e-09	4.72e-05	7.124	4	17	56
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	5.19e-09	5.07e-05	7.099	4	16	57
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.41e-09	6.26e-05	7.025	4	17	60
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	6.86e-09	6.70e-05	7.001	4	16	61
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	8.90e-09	8.69e-05	6.909	4	17	65
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.20e-08	1.18e-04	6.802	4	16	70
GO:0005839	proteasome core complex	3.60e-08	3.52e-04	8.516	3	9	16
GO:0000209	protein polyubiquitination	3.66e-08	3.58e-04	6.408	4	16	92
GO:0004298	threonine-type endopeptidase activity	4.37e-08	4.27e-04	8.429	3	9	17
GO:0034641	cellular nitrogen compound metabolic process	6.26e-08	6.11e-04	6.217	4	18	105
GO:0042981	regulation of apoptotic process	8.13e-08	7.94e-04	6.124	4	18	112
GO:0000082	G1/S transition of mitotic cell cycle	1.27e-07	1.24e-03	5.966	4	24	125
GO:0016032	viral process	1.58e-07	1.54e-03	4.512	5	32	428
GO:0016071	mRNA metabolic process	4.37e-07	4.27e-03	5.522	4	21	170
GO:0016070	RNA metabolic process	6.56e-07	6.40e-03	5.377	4	21	188
GO:0019773	proteasome core complex, alpha-subunit complex	3.14e-06	3.07e-02	9.347	2	4	6
GO:0000278	mitotic cell cycle	5.11e-06	4.99e-02	4.637	4	35	314
GO:0043066	negative regulation of apoptotic process	5.65e-06	5.52e-02	4.601	4	20	322
GO:0005654	nucleoplasm	5.75e-06	5.61e-02	3.479	5	55	876
GO:0006915	apoptotic process	1.50e-05	1.46e-01	4.248	4	21	411
GO:0010467	gene expression	4.26e-05	4.16e-01	3.868	4	31	535
GO:0005829	cytosol	2.04e-04	1.00e+00	2.450	5	58	1787
GO:0044281	small molecule metabolic process	2.58e-04	1.00e+00	3.210	4	32	844
GO:0030891	VCB complex	1.02e-03	1.00e+00	9.931	1	1	2
GO:0031467	Cul7-RING ubiquitin ligase complex	1.02e-03	1.00e+00	9.931	1	1	2
GO:0019788	NEDD8 ligase activity	2.05e-03	1.00e+00	8.931	1	1	4
GO:0031461	cullin-RING ubiquitin ligase complex	2.05e-03	1.00e+00	8.931	1	2	4
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	2.56e-03	1.00e+00	8.610	1	2	5
GO:0031462	Cul2-RING ubiquitin ligase complex	3.07e-03	1.00e+00	8.347	1	1	6
GO:0031466	Cul5-RING ubiquitin ligase complex	3.07e-03	1.00e+00	8.347	1	1	6
GO:0070062	extracellular vesicular exosome	3.44e-03	1.00e+00	2.251	4	43	1641
GO:0045116	protein neddylation	3.58e-03	1.00e+00	8.124	1	1	7
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	3.58e-03	1.00e+00	8.124	1	2	7
GO:0022624	proteasome accessory complex	7.15e-03	1.00e+00	7.124	1	7	14
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	8.17e-03	1.00e+00	6.931	1	1	16
GO:0031463	Cul3-RING ubiquitin ligase complex	8.17e-03	1.00e+00	6.931	1	1	16
GO:0006513	protein monoubiquitination	8.68e-03	1.00e+00	6.844	1	1	17
GO:0005844	polysome	9.69e-03	1.00e+00	6.684	1	1	19
GO:0019005	SCF ubiquitin ligase complex	1.02e-02	1.00e+00	6.610	1	1	20
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	1.12e-02	1.00e+00	6.472	1	1	22
GO:0005730	nucleolus	1.59e-02	1.00e+00	2.267	3	41	1217
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	2.84e-02	1.00e+00	5.124	1	3	56
GO:0015630	microtubule cytoskeleton	3.78e-02	1.00e+00	4.703	1	2	75
GO:0071456	cellular response to hypoxia	3.83e-02	1.00e+00	4.684	1	2	76
GO:0007219	Notch signaling pathway	4.77e-02	1.00e+00	4.362	1	4	95
GO:0016887	ATPase activity	5.02e-02	1.00e+00	4.288	1	6	100
GO:0032403	protein complex binding	6.48e-02	1.00e+00	3.909	1	2	130
GO:0031625	ubiquitin protein ligase binding	6.87e-02	1.00e+00	3.823	1	5	138
GO:0004842	ubiquitin-protein transferase activity	8.84e-02	1.00e+00	3.448	1	2	179
GO:0016567	protein ubiquitination	9.26e-02	1.00e+00	3.377	1	3	188
GO:0006281	DNA repair	9.97e-02	1.00e+00	3.266	1	19	203
GO:0005515	protein binding	1.05e-01	1.00e+00	0.922	4	76	4124
GO:0005813	centrosome	1.06e-01	1.00e+00	3.170	1	8	217
GO:0006200	ATP catabolic process	1.07e-01	1.00e+00	3.157	1	8	219
GO:0003723	RNA binding	1.20e-01	1.00e+00	2.983	1	11	247
GO:0006508	proteolysis	1.28e-01	1.00e+00	2.887	1	3	264
GO:0005634	nucleus	2.08e-01	1.00e+00	0.852	3	67	3246
GO:0008270	zinc ion binding	3.21e-01	1.00e+00	1.426	1	7	727
GO:0005737	cytoplasm	7.92e-01	1.00e+00	-0.431	1	50	2633

Wolf-ratios-Mammosphere-Adherent

reg-snw-5686

Statistics

Genes (5)

Interactions (4)

Related GO terms (63)