reg-snw-10213

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.815	1.49e-06	3.74e-03	6.93e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-10213 subnetwork

Genes (7)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
PSMA1	5682	5	0.996	0.878	29	-	Yes	-
PSMB2	5690	23	0.877	0.956	52	-	Yes	-
PSMD1	5707	2	0.836	0.830	5	-	Yes	-
PSMA3	5684	1	0.533	0.815	20	-	Yes	-
RBX1	9978	8	1.185	0.934	9	TF	Yes	-
PSMB7	5695	10	0.982	0.934	33	-	Yes	-
[ PSMD14 ]	10213	1	0.299	0.815	32	TF	-	-

Interactions (6)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PSMB2	5690	PSMD14	10213	pd	<	reg.ITFP.txt: no annot
PSMB7	5695	RBX1	9978	pd	<	reg.ITFP.txt: no annot
PSMB7	5695	PSMD14	10213	pd	<	reg.ITFP.txt: no annot
PSMA3	5684	PSMD14	10213	pd	<	reg.ITFP.txt: no annot
PSMD1	5707	PSMD14	10213	pd	<	reg.ITFP.txt: no annot
PSMA1	5682	PSMD14	10213	pd	<	reg.ITFP.txt: no annot

Related GO terms (78)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006521	regulation of cellular amino acid metabolic process	2.61e-14	2.55e-10	7.673	6	16	41
GO:0000502	proteasome complex	6.23e-14	6.08e-10	7.476	6	17	47
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.18e-13	1.15e-09	7.331	6	17	52
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	1.33e-13	1.30e-09	7.303	6	17	53
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.88e-13	1.84e-09	7.224	6	17	56
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	2.10e-13	2.05e-09	7.198	6	16	57
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.90e-13	2.83e-09	7.124	6	17	60
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	3.22e-13	3.14e-09	7.100	6	16	61
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	4.78e-13	4.67e-09	7.009	6	17	65
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	7.59e-13	7.41e-09	6.902	6	16	70
GO:0000209	protein polyubiquitination	4.12e-12	4.02e-08	6.507	6	16	92
GO:0034641	cellular nitrogen compound metabolic process	9.29e-12	9.07e-08	6.317	6	18	105
GO:0042981	regulation of apoptotic process	1.38e-11	1.35e-07	6.224	6	18	112
GO:0000082	G1/S transition of mitotic cell cycle	2.70e-11	2.64e-07	6.065	6	24	125
GO:0005839	proteasome core complex	1.68e-10	1.64e-06	8.446	4	9	16
GO:0016071	mRNA metabolic process	1.76e-10	1.72e-06	5.622	6	21	170
GO:0004298	threonine-type endopeptidase activity	2.19e-10	2.14e-06	8.359	4	9	17
GO:0016032	viral process	2.96e-10	2.89e-06	4.512	7	32	428
GO:0016070	RNA metabolic process	3.24e-10	3.16e-06	5.476	6	21	188
GO:0000278	mitotic cell cycle	7.19e-09	7.02e-05	4.736	6	35	314
GO:0043066	negative regulation of apoptotic process	8.36e-09	8.17e-05	4.700	6	20	322
GO:0006915	apoptotic process	3.62e-08	3.54e-04	4.348	6	21	411
GO:0005654	nucleoplasm	4.57e-08	4.47e-04	3.479	7	55	876
GO:0010467	gene expression	1.76e-07	1.72e-03	3.968	6	31	535
GO:0044281	small molecule metabolic process	2.66e-06	2.60e-02	3.310	6	32	844
GO:0019773	proteasome core complex, alpha-subunit complex	6.60e-06	6.44e-02	8.861	2	4	6
GO:0005829	cytosol	6.81e-06	6.65e-02	2.450	7	58	1787
GO:0022624	proteasome accessory complex	3.99e-05	3.90e-01	7.639	2	7	14
GO:0070062	extracellular vesicular exosome	1.34e-04	1.00e+00	2.351	6	43	1641
GO:0008541	proteasome regulatory particle, lid subcomplex	7.17e-04	1.00e+00	10.446	1	1	1
GO:0030891	VCB complex	1.43e-03	1.00e+00	9.446	1	1	2
GO:0031467	Cul7-RING ubiquitin ligase complex	1.43e-03	1.00e+00	9.446	1	1	2
GO:0061133	endopeptidase activator activity	2.15e-03	1.00e+00	8.861	1	1	3
GO:0019788	NEDD8 ligase activity	2.86e-03	1.00e+00	8.446	1	1	4
GO:0010950	positive regulation of endopeptidase activity	2.86e-03	1.00e+00	8.446	1	1	4
GO:0031461	cullin-RING ubiquitin ligase complex	2.86e-03	1.00e+00	8.446	1	2	4
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	3.58e-03	1.00e+00	8.124	1	2	5
GO:0031462	Cul2-RING ubiquitin ligase complex	4.29e-03	1.00e+00	7.861	1	1	6
GO:0031466	Cul5-RING ubiquitin ligase complex	4.29e-03	1.00e+00	7.861	1	1	6
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	5.01e-03	1.00e+00	7.639	1	2	7
GO:0045116	protein neddylation	5.01e-03	1.00e+00	7.639	1	1	7
GO:0070628	proteasome binding	5.72e-03	1.00e+00	7.446	1	1	8
GO:0061136	regulation of proteasomal protein catabolic process	6.44e-03	1.00e+00	7.276	1	1	9
GO:0005838	proteasome regulatory particle	7.15e-03	1.00e+00	7.124	1	4	10
GO:0030234	enzyme regulator activity	7.86e-03	1.00e+00	6.987	1	2	11
GO:0070536	protein K63-linked deubiquitination	8.57e-03	1.00e+00	6.861	1	1	12
GO:0010243	response to organonitrogen compound	1.00e-02	1.00e+00	6.639	1	1	14
GO:0042176	regulation of protein catabolic process	1.00e-02	1.00e+00	6.639	1	2	14
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	1.14e-02	1.00e+00	6.446	1	1	16
GO:0031463	Cul3-RING ubiquitin ligase complex	1.14e-02	1.00e+00	6.446	1	1	16
GO:0006513	protein monoubiquitination	1.21e-02	1.00e+00	6.359	1	1	17
GO:0006303	double-strand break repair via nonhomologous end joining	1.28e-02	1.00e+00	6.276	1	4	18
GO:0005844	polysome	1.35e-02	1.00e+00	6.198	1	1	19
GO:0019005	SCF ubiquitin ligase complex	1.43e-02	1.00e+00	6.124	1	1	20
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	1.57e-02	1.00e+00	5.987	1	1	22
GO:0004221	ubiquitin thiolesterase activity	1.92e-02	1.00e+00	5.691	1	1	27
GO:0014070	response to organic cyclic compound	2.41e-02	1.00e+00	5.359	1	1	34
GO:0008237	metallopeptidase activity	2.69e-02	1.00e+00	5.198	1	1	38
GO:0000724	double-strand break repair via homologous recombination	2.97e-02	1.00e+00	5.054	1	5	42
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	3.95e-02	1.00e+00	4.639	1	3	56
GO:0005634	nucleus	4.47e-02	1.00e+00	1.104	5	67	3246
GO:0005730	nucleolus	4.59e-02	1.00e+00	1.782	3	41	1217
GO:0015630	microtubule cytoskeleton	5.26e-02	1.00e+00	4.217	1	2	75
GO:0071456	cellular response to hypoxia	5.32e-02	1.00e+00	4.198	1	2	76
GO:0006511	ubiquitin-dependent protein catabolic process	6.41e-02	1.00e+00	3.922	1	2	92
GO:0007219	Notch signaling pathway	6.62e-02	1.00e+00	3.876	1	4	95
GO:0032403	protein complex binding	8.96e-02	1.00e+00	3.424	1	2	130
GO:0031625	ubiquitin protein ligase binding	9.49e-02	1.00e+00	3.338	1	5	138
GO:0005515	protein binding	1.19e-01	1.00e+00	0.758	5	76	4124
GO:0004842	ubiquitin-protein transferase activity	1.22e-01	1.00e+00	2.962	1	2	179
GO:0016567	protein ubiquitination	1.27e-01	1.00e+00	2.891	1	3	188
GO:0006281	DNA repair	1.37e-01	1.00e+00	2.781	1	19	203
GO:0005813	centrosome	1.46e-01	1.00e+00	2.684	1	8	217
GO:0003723	RNA binding	1.64e-01	1.00e+00	2.498	1	11	247
GO:0016020	membrane	2.11e-01	1.00e+00	1.209	2	38	1207
GO:0008270	zinc ion binding	4.18e-01	1.00e+00	0.940	1	7	727
GO:0046872	metal ion binding	5.05e-01	1.00e+00	0.579	1	10	934
GO:0005737	cytoplasm	8.89e-01	1.00e+00	-0.916	1	50	2633

Wolf-ratios-Mammosphere-Adherent

reg-snw-10213

Statistics

Genes (7)

Interactions (6)

Related GO terms (78)