reg-snw-1434

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.865	2.23e-07	1.35e-03	2.78e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-1434 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
CAD	790	25	0.807	0.973	67	-	-	-
CCNA2	890	10	0.550	0.973	246	TF	Yes	-
RUVBL1	8607	24	0.720	0.973	126	TF	Yes	-
RBX1	9978	8	1.185	0.934	9	TF	Yes	-
HNRNPC	3183	40	1.812	0.973	62	-	Yes	-
PSMB7	5695	10	0.982	0.934	33	-	Yes	-
[ CSE1L ]	1434	1	0.304	0.865	54	-	Yes	-
PSMA1	5682	5	0.996	0.878	29	-	Yes	-
RPA1	6117	2	0.425	0.865	74	TF	-	-

Interactions (9)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CCNA2	890	CSE1L	1434	pd	>	reg.ITFP.txt: no annot
PSMB7	5695	RBX1	9978	pd	<	reg.ITFP.txt: no annot
CCNA2	890	RUVBL1	8607	pd	<>	reg.ITFP.txt: no annot
CAD	790	RPA1	6117	pd	<	reg.ITFP.txt: no annot
PSMA1	5682	RPA1	6117	pd	<	reg.ITFP.txt: no annot
CAD	790	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
CSE1L	1434	RPA1	6117	pd	<	reg.ITFP.txt: no annot
PSMB7	5695	RPA1	6117	pd	<	reg.ITFP.txt: no annot
HNRNPC	3183	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot

Related GO terms (179)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005654	nucleoplasm	1.40e-06	1.37e-02	3.116	7	55	876
GO:0005839	proteasome core complex	9.00e-05	8.79e-01	7.083	2	9	16
GO:0004298	threonine-type endopeptidase activity	1.02e-04	9.96e-01	6.996	2	9	17
GO:0000278	mitotic cell cycle	1.16e-04	1.00e+00	3.789	4	35	314
GO:0000082	G1/S transition of mitotic cell cycle	1.63e-04	1.00e+00	4.703	3	24	125
GO:0005730	nucleolus	2.22e-04	1.00e+00	2.419	6	41	1217
GO:0006521	regulation of cellular amino acid metabolic process	6.08e-04	1.00e+00	5.726	2	16	41
GO:0006281	DNA repair	6.78e-04	1.00e+00	4.003	3	19	203
GO:0031100	organ regeneration	7.00e-04	1.00e+00	5.624	2	2	44
GO:0000502	proteasome complex	7.99e-04	1.00e+00	5.529	2	17	47
GO:0006310	DNA recombination	9.04e-04	1.00e+00	5.440	2	6	50
GO:0004151	dihydroorotase activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0004070	aspartate carbamoyltransferase activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0070335	aspartate binding	9.22e-04	1.00e+00	10.083	1	1	1
GO:0008262	importin-alpha export receptor activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0070409	carbamoyl phosphate biosynthetic process	9.22e-04	1.00e+00	10.083	1	1	1
GO:0005634	nucleus	9.40e-04	1.00e+00	1.419	8	67	3246
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	9.78e-04	1.00e+00	5.383	2	17	52
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	1.02e-03	1.00e+00	5.356	2	17	53
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.13e-03	1.00e+00	5.276	2	17	56
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	1.17e-03	1.00e+00	5.251	2	16	57
GO:0070062	extracellular vesicular exosome	1.18e-03	1.00e+00	1.988	6	43	1641
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.30e-03	1.00e+00	5.177	2	17	60
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	1.34e-03	1.00e+00	5.153	2	16	61
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.52e-03	1.00e+00	5.061	2	17	65
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.77e-03	1.00e+00	4.954	2	16	70
GO:0030891	VCB complex	1.84e-03	1.00e+00	9.083	1	1	2
GO:0031467	Cul7-RING ubiquitin ligase complex	1.84e-03	1.00e+00	9.083	1	1	2
GO:0016363	nuclear matrix	1.92e-03	1.00e+00	4.894	2	7	73
GO:0006543	glutamine catabolic process	2.76e-03	1.00e+00	8.499	1	1	3
GO:0044205	'de novo' UMP biosynthetic process	2.76e-03	1.00e+00	8.499	1	1	3
GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	2.76e-03	1.00e+00	8.499	1	1	3
GO:0000209	protein polyubiquitination	3.03e-03	1.00e+00	4.560	2	16	92
GO:0051414	response to cortisol	3.68e-03	1.00e+00	8.083	1	1	4
GO:0031461	cullin-RING ubiquitin ligase complex	3.68e-03	1.00e+00	8.083	1	2	4
GO:0006228	UTP biosynthetic process	3.68e-03	1.00e+00	8.083	1	1	4
GO:0001940	male pronucleus	3.68e-03	1.00e+00	8.083	1	1	4
GO:0019788	NEDD8 ligase activity	3.68e-03	1.00e+00	8.083	1	1	4
GO:0034641	cellular nitrogen compound metabolic process	3.92e-03	1.00e+00	4.369	2	18	105
GO:0042981	regulation of apoptotic process	4.45e-03	1.00e+00	4.276	2	18	112
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	4.60e-03	1.00e+00	7.762	1	2	5
GO:0014075	response to amine	4.60e-03	1.00e+00	7.762	1	1	5
GO:0000730	DNA recombinase assembly	4.60e-03	1.00e+00	7.762	1	3	5
GO:0001939	female pronucleus	4.60e-03	1.00e+00	7.762	1	1	5
GO:0000800	lateral element	4.60e-03	1.00e+00	7.762	1	1	5
GO:0006915	apoptotic process	5.14e-03	1.00e+00	2.985	3	21	411
GO:0019773	proteasome core complex, alpha-subunit complex	5.52e-03	1.00e+00	7.499	1	4	6
GO:0046134	pyrimidine nucleoside biosynthetic process	5.52e-03	1.00e+00	7.499	1	1	6
GO:0031000	response to caffeine	5.52e-03	1.00e+00	7.499	1	1	6
GO:0031462	Cul2-RING ubiquitin ligase complex	5.52e-03	1.00e+00	7.499	1	1	6
GO:0031466	Cul5-RING ubiquitin ligase complex	5.52e-03	1.00e+00	7.499	1	1	6
GO:0005515	protein binding	5.67e-03	1.00e+00	1.074	8	76	4124
GO:0016032	viral process	5.76e-03	1.00e+00	2.927	3	32	428
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	6.44e-03	1.00e+00	7.276	1	2	7
GO:0010389	regulation of G2/M transition of mitotic cell cycle	6.44e-03	1.00e+00	7.276	1	1	7
GO:0033762	response to glucagon	6.44e-03	1.00e+00	7.276	1	1	7
GO:0000812	Swr1 complex	6.44e-03	1.00e+00	7.276	1	2	7
GO:0045116	protein neddylation	6.44e-03	1.00e+00	7.276	1	1	7
GO:0005662	DNA replication factor A complex	7.35e-03	1.00e+00	7.083	1	3	8
GO:0031011	Ino80 complex	7.35e-03	1.00e+00	7.083	1	2	8
GO:0008266	poly(U) RNA binding	8.27e-03	1.00e+00	6.914	1	1	9
GO:0006541	glutamine metabolic process	9.18e-03	1.00e+00	6.762	1	1	10
GO:0001673	male germ cell nucleus	9.18e-03	1.00e+00	6.762	1	1	10
GO:0006261	DNA-dependent DNA replication	9.18e-03	1.00e+00	6.762	1	2	10
GO:0043968	histone H2A acetylation	9.18e-03	1.00e+00	6.762	1	2	10
GO:0007126	meiotic nuclear division	9.18e-03	1.00e+00	6.762	1	1	10
GO:0007067	mitotic nuclear division	9.45e-03	1.00e+00	3.717	2	8	165
GO:0016071	mRNA metabolic process	1.00e-02	1.00e+00	3.674	2	21	170
GO:0070935	3'-UTR-mediated mRNA stabilization	1.01e-02	1.00e+00	6.624	1	2	11
GO:0045120	pronucleus	1.01e-02	1.00e+00	6.624	1	1	11
GO:0010467	gene expression	1.07e-02	1.00e+00	2.605	3	31	535
GO:0035267	NuA4 histone acetyltransferase complex	1.10e-02	1.00e+00	6.499	1	3	12
GO:0007095	mitotic G2 DNA damage checkpoint	1.19e-02	1.00e+00	6.383	1	1	13
GO:0016070	RNA metabolic process	1.21e-02	1.00e+00	3.529	2	21	188
GO:0048873	homeostasis of number of cells within a tissue	1.28e-02	1.00e+00	6.276	1	1	14
GO:0005829	cytosol	1.34e-02	1.00e+00	1.602	5	58	1787
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	1.47e-02	1.00e+00	6.083	1	1	16
GO:0031463	Cul3-RING ubiquitin ligase complex	1.47e-02	1.00e+00	6.083	1	1	16
GO:0043234	protein complex	1.50e-02	1.00e+00	3.369	2	8	210
GO:0006206	pyrimidine nucleobase metabolic process	1.56e-02	1.00e+00	5.996	1	2	17
GO:0006513	protein monoubiquitination	1.56e-02	1.00e+00	5.996	1	1	17
GO:0006298	mismatch repair	1.56e-02	1.00e+00	5.996	1	4	17
GO:0000718	nucleotide-excision repair, DNA damage removal	1.56e-02	1.00e+00	5.996	1	5	17
GO:0006611	protein export from nucleus	1.65e-02	1.00e+00	5.914	1	2	18
GO:0071364	cellular response to epidermal growth factor stimulus	1.65e-02	1.00e+00	5.914	1	1	18
GO:0006297	nucleotide-excision repair, DNA gap filling	1.65e-02	1.00e+00	5.914	1	5	18
GO:0003678	DNA helicase activity	1.65e-02	1.00e+00	5.914	1	3	18
GO:0071339	MLL1 complex	1.65e-02	1.00e+00	5.914	1	2	18
GO:0033574	response to testosterone	1.65e-02	1.00e+00	5.914	1	1	18
GO:0005844	polysome	1.74e-02	1.00e+00	5.836	1	1	19
GO:0016020	membrane	1.75e-02	1.00e+00	1.846	4	38	1207
GO:0043044	ATP-dependent chromatin remodeling	1.83e-02	1.00e+00	5.762	1	2	20
GO:0034080	CENP-A containing nucleosome assembly	1.83e-02	1.00e+00	5.762	1	2	20
GO:0019005	SCF ubiquitin ligase complex	1.83e-02	1.00e+00	5.762	1	1	20
GO:0032201	telomere maintenance via semi-conservative replication	1.83e-02	1.00e+00	5.762	1	7	20
GO:0008536	Ran GTPase binding	1.92e-02	1.00e+00	5.691	1	1	21
GO:0017144	drug metabolic process	1.92e-02	1.00e+00	5.691	1	1	21
GO:0043967	histone H4 acetylation	2.01e-02	1.00e+00	5.624	1	2	22
GO:0000722	telomere maintenance via recombination	2.01e-02	1.00e+00	5.624	1	7	22
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	2.01e-02	1.00e+00	5.624	1	1	22
GO:0003723	RNA binding	2.04e-02	1.00e+00	3.135	2	11	247
GO:0003730	mRNA 3'-UTR binding	2.28e-02	1.00e+00	5.440	1	2	25
GO:0031492	nucleosomal DNA binding	2.28e-02	1.00e+00	5.440	1	2	25
GO:0006271	DNA strand elongation involved in DNA replication	2.64e-02	1.00e+00	5.225	1	8	29
GO:0018107	peptidyl-threonine phosphorylation	2.64e-02	1.00e+00	5.225	1	2	29
GO:0043195	terminal bouton	2.82e-02	1.00e+00	5.129	1	1	31
GO:0007595	lactation	2.91e-02	1.00e+00	5.083	1	2	32
GO:0006284	base-excision repair	2.91e-02	1.00e+00	5.083	1	8	32
GO:0048146	positive regulation of fibroblast proliferation	3.18e-02	1.00e+00	4.954	1	1	35
GO:0043066	negative regulation of apoptotic process	3.35e-02	1.00e+00	2.753	2	20	322
GO:0040008	regulation of growth	3.36e-02	1.00e+00	4.874	1	2	37
GO:0035690	cellular response to drug	3.45e-02	1.00e+00	4.836	1	2	38
GO:0032508	DNA duplex unwinding	3.45e-02	1.00e+00	4.836	1	5	38
GO:0006283	transcription-coupled nucleotide-excision repair	3.63e-02	1.00e+00	4.762	1	6	40
GO:0044281	small molecule metabolic process	3.64e-02	1.00e+00	1.947	3	32	844
GO:0042995	cell projection	3.72e-02	1.00e+00	4.726	1	2	41
GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	3.72e-02	1.00e+00	4.726	1	2	41
GO:0003684	damaged DNA binding	3.72e-02	1.00e+00	4.726	1	9	41
GO:0000724	double-strand break repair via homologous recombination	3.81e-02	1.00e+00	4.691	1	5	42
GO:0042802	identical protein binding	3.99e-02	1.00e+00	2.616	2	7	354
GO:0000723	telomere maintenance	4.25e-02	1.00e+00	4.529	1	8	47
GO:0030097	hemopoiesis	4.34e-02	1.00e+00	4.499	1	3	48
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	4.43e-02	1.00e+00	4.469	1	3	49
GO:0006334	nucleosome assembly	4.61e-02	1.00e+00	4.411	1	4	51
GO:0055086	nucleobase-containing small molecule metabolic process	4.61e-02	1.00e+00	4.411	1	5	51
GO:0006302	double-strand break repair	4.69e-02	1.00e+00	4.383	1	8	52
GO:0006289	nucleotide-excision repair	4.78e-02	1.00e+00	4.356	1	9	53
GO:0005681	spliceosomal complex	4.96e-02	1.00e+00	4.302	1	2	55
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	5.05e-02	1.00e+00	4.276	1	3	56
GO:0032355	response to estradiol	5.13e-02	1.00e+00	4.251	1	1	57
GO:0003697	single-stranded DNA binding	5.13e-02	1.00e+00	4.251	1	6	57
GO:0007265	Ras protein signal transduction	5.31e-02	1.00e+00	4.201	1	3	59
GO:0071013	catalytic step 2 spliceosome	5.49e-02	1.00e+00	4.153	1	5	61
GO:0007565	female pregnancy	5.75e-02	1.00e+00	4.083	1	2	64
GO:0006325	chromatin organization	6.27e-02	1.00e+00	3.954	1	3	70
GO:0001889	liver development	6.36e-02	1.00e+00	3.934	1	1	71
GO:0001649	osteoblast differentiation	6.62e-02	1.00e+00	3.874	1	2	74
GO:0015630	microtubule cytoskeleton	6.71e-02	1.00e+00	3.855	1	2	75
GO:0071456	cellular response to hypoxia	6.79e-02	1.00e+00	3.836	1	2	76
GO:0005815	microtubule organizing center	6.88e-02	1.00e+00	3.817	1	1	77
GO:0016605	PML body	7.05e-02	1.00e+00	3.780	1	4	79
GO:0030529	ribonucleoprotein complex	7.31e-02	1.00e+00	3.726	1	4	82
GO:0006260	DNA replication	8.34e-02	1.00e+00	3.529	1	11	94
GO:0007219	Notch signaling pathway	8.43e-02	1.00e+00	3.514	1	4	95
GO:0000086	G2/M transition of mitotic cell cycle	8.60e-02	1.00e+00	3.484	1	5	97
GO:0016887	ATPase activity	8.85e-02	1.00e+00	3.440	1	6	100
GO:0007507	heart development	9.36e-02	1.00e+00	3.356	1	1	106
GO:0046777	protein autophosphorylation	9.36e-02	1.00e+00	3.356	1	2	106
GO:0000790	nuclear chromatin	9.61e-02	1.00e+00	3.315	1	3	109
GO:0004672	protein kinase activity	1.10e-01	1.00e+00	3.118	1	2	125
GO:0000398	mRNA splicing, via spliceosome	1.12e-01	1.00e+00	3.083	1	8	128
GO:0032403	protein complex binding	1.14e-01	1.00e+00	3.061	1	2	130
GO:0015629	actin cytoskeleton	1.19e-01	1.00e+00	2.996	1	2	136
GO:0031625	ubiquitin protein ligase binding	1.20e-01	1.00e+00	2.975	1	5	138
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.24e-01	1.00e+00	2.934	1	2	142
GO:0001701	in utero embryonic development	1.33e-01	1.00e+00	2.817	1	3	154
GO:0008270	zinc ion binding	1.41e-01	1.00e+00	1.578	2	7	727
GO:0008380	RNA splicing	1.42e-01	1.00e+00	2.717	1	7	165
GO:0007283	spermatogenesis	1.45e-01	1.00e+00	2.691	1	2	168
GO:0043025	neuronal cell body	1.47e-01	1.00e+00	2.666	1	3	171
GO:0000166	nucleotide binding	1.51e-01	1.00e+00	2.624	1	6	176
GO:0004842	ubiquitin-protein transferase activity	1.53e-01	1.00e+00	2.600	1	2	179
GO:0016567	protein ubiquitination	1.61e-01	1.00e+00	2.529	1	3	188
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.72e-01	1.00e+00	2.418	1	1	203
GO:0019899	enzyme binding	1.78e-01	1.00e+00	2.369	1	4	210
GO:0005813	centrosome	1.83e-01	1.00e+00	2.322	1	8	217
GO:0043231	intracellular membrane-bounded organelle	1.84e-01	1.00e+00	2.315	1	7	218
GO:0019901	protein kinase binding	1.95e-01	1.00e+00	2.225	1	11	232
GO:0005524	ATP binding	1.96e-01	1.00e+00	1.283	2	23	892
GO:0008283	cell proliferation	2.00e-01	1.00e+00	2.183	1	6	239
GO:0005737	cytoplasm	2.04e-01	1.00e+00	0.721	4	50	2633
GO:0003682	chromatin binding	2.10e-01	1.00e+00	2.106	1	6	252
GO:0008284	positive regulation of cell proliferation	2.30e-01	1.00e+00	1.959	1	2	279
GO:0045893	positive regulation of transcription, DNA-templated	2.98e-01	1.00e+00	1.525	1	10	377
GO:0005794	Golgi apparatus	3.24e-01	1.00e+00	1.387	1	5	415
GO:0044822	poly(A) RNA binding	5.36e-01	1.00e+00	0.441	1	25	799
GO:0046872	metal ion binding	5.96e-01	1.00e+00	0.216	1	10	934
GO:0006351	transcription, DNA-templated	6.50e-01	1.00e+00	0.012	1	9	1076

Wolf-ratios-Mammosphere-Adherent

reg-snw-1434

Statistics

Genes (9)

Interactions (9)

Related GO terms (179)