meta-int-snw-4137

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-11277 wolf-screen-ratio-mammosphere-adherent 0.882 1.09e-07 9.11e-04 1.96e-03 10 9
int-snw-4137 wolf-screen-ratio-mammosphere-adherent 0.985 1.73e-17 8.02e-04 1.75e-02 14 12
reg-snw-4522 wolf-screen-ratio-mammosphere-adherent 0.815 1.50e-06 3.75e-03 6.95e-03 14 12
reg-snw-56655 wolf-screen-ratio-mammosphere-adherent 0.828 9.29e-07 2.91e-03 5.53e-03 8 7
reg-snw-317781 wolf-screen-ratio-mammosphere-adherent 0.823 1.13e-06 3.23e-03 6.07e-03 9 9
reg-snw-1434 wolf-screen-ratio-mammosphere-adherent 0.865 2.23e-07 1.35e-03 2.78e-03 9 7
reg-snw-5925 wolf-screen-ratio-mammosphere-adherent 0.802 2.42e-06 4.82e-03 8.69e-03 8 5
reg-snw-10213 wolf-screen-ratio-mammosphere-adherent 0.815 1.49e-06 3.74e-03 6.93e-03 7 6
reg-snw-5686 wolf-screen-ratio-mammosphere-adherent 0.878 1.30e-07 1.01e-03 2.15e-03 5 4
wolf-screen-ratio-mammosphere-adherent-meta-int-snw-4137 subnetwork

Genes (45)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
PSMB1 5689 610.6880.901113Yes-
PSMA3 5684 900.5330.815238Yes-
PPCS 79717 31-0.5690.8022-Yes
PSMA2 5683 1121.0931.106108Yes-
POLR2F 5435 620.8910.95626Yes-
CSE1L 1434 410.3040.86554Yes-
VARS 7407 860.5491.002204Yes-
DDX51 317781 530.0590.823210Yes-
TFRC 7037 310.7300.80217--
RPA2 6118 961.2501.15176Yes-
CAD 790 910.8070.973400--
EIF6 3692 670.7000.876316Yes-
RB1 5925 31-0.1020.802351--
CCNA2 890 540.5500.973246Yes-
PSMD1 5707 860.8360.830118Yes-
PPP2R1A 5518 190.6440.985249Yes-
EFTUD2 9343 930.8830.956108Yes-
PSMD14 10213 440.2990.81532--
TUBG1 7283 980.9740.97391Yes-
PSMD11 5717 1241.0951.106218Yes-
RAN 5901 890.6320.899258Yes-
CASP8 841 120.8041.041141--
PRMT3 10196 490.4310.81526--
PSMA5 5686 350.3780.87833--
MTHFD1 4522 490.1940.81526Yes-
RBX1 9978 1151.1850.934148Yes-
PPIE 10450 310.5670.80241--
HNRNPC 3183 1081.8120.973181Yes-
PSMB7 5695 1180.9820.93490Yes-
PSMA1 5682 1000.9960.878152Yes-
TREX1 11277 51-0.0510.88291Yes-
OGDH 4967 720.8470.802126Yes-
POLE4 56655 630.1770.82856--
PSMB3 5691 640.6680.90119Yes-
RPSA 3921 1201.3271.151152Yes-
RPA1 6117 510.4250.86574--
PGD 5226 891.2011.106152Yes-
CDC16 8881 530.9501.02080Yes-
RUVBL1 8607 950.7200.973469Yes-
PSMD3 5709 1000.9861.106201Yes-
PSMB2 5690 1160.8770.956169Yes-
ACTB 60 1341.1531.151610Yes-
RUVBL2 10856 950.6930.956532Yes-
PSMD6 9861 790.8480.878143Yes-
MAPT 4137 9-0.1190.98565--

Interactions (222)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMA3 5684 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, Krogan_Core
PSMD11 5717 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, INTEROLOG
HNRNPC 3183 PSMA3 5684 pp -- int.I2D: BioGrid
PSMA1 5682 PSMB2 5690 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
PSMA5 5686 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMD11 5717 RUVBL1 8607 pp -- int.I2D: YeastLow
PSMA1 5682 PSMB1 5689 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, BIND_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, IntAct, IntAct_Mouse, IntAct_Yeast, Yu_GoldStd
CSE1L 1434 PSMD14 10213 pd < reg.ITFP.txt: no annot
PPP2R1A 5518 PSMB3 5691 pp -- int.I2D: IntAct_Mouse
CSE1L 1434 RAN 5901 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid_Yeast, HPRD, IntAct_Yeast, MIPS, IntAct, INTEROLOG;
int.HPRD: in vitro
CAD 790 CDC16 8881 pp -- int.I2D: IntAct_Yeast
RB1 5925 PPCS 79717 pd > reg.pazar.txt: no annot
EFTUD2 9343 RUVBL2 10856 pd < reg.ITFP.txt: no annot
EFTUD2 9343 RUVBL2 10856 pp -- int.I2D: BioGrid
CAD 790 RPA1 6117 pd < reg.ITFP.txt: no annot
MTHFD1 4522 PSMA3 5684 pp -- int.I2D: BioGrid
PSMB2 5690 TREX1 11277 pd < reg.ITFP.txt: no annot
RB1 5925 RPA2 6118 pd > reg.pazar.txt: no annot
PSMD1 5707 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, Krogan_Core
PSMA5 5686 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RUVBL1 8607 pp -- int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
MAPT 4137 PPP2R1A 5518 pp -- int.I2D: MINT;
int.Mint: MI:0208(genetic interaction)
PGD 5226 RAN 5901 pp -- int.I2D: YeastLow
CCNA2 890 RUVBL1 8607 pd <> reg.ITFP.txt: no annot
PSMB3 5691 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPA1 6117 RUVBL1 8607 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
RPA1 6117 VARS 7407 pp -- int.I2D: YeastLow
CAD 790 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow
PSMB1 5689 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RAN 5901 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastHigh, IntAct, Yu_GoldStd;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
PSMB2 5690 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMB3 5691 PSMD3 5709 pp -- int.I2D: YeastLow
PSMA2 5683 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
PPP2R1A 5518 PSMA1 5682 pp -- int.I2D: IntAct_Mouse
PPP2R1A 5518 PSMB1 5689 pp -- int.I2D: IntAct_Mouse
CAD 790 RUVBL1 8607 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL1 8607 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA2 5683 PSMA5 5686 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, MINT_Yeast, YeastHigh, BIND_Yeast, IntAct_Fly, Krogan_Core
RPA1 6117 TREX1 11277 pp -- int.I2D: BCI;
int.HPRD: in vitro
PSMA3 5684 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMD14 10213 pp -- int.I2D: BioGrid, BioGrid_Yeast
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
PGD 5226 RB1 5925 pd < reg.pazar.txt: no annot
CCNA2 890 CSE1L 1434 pd > reg.ITFP.txt: no annot
OGDH 4967 RUVBL1 8607 pp -- int.I2D: YeastLow
RPA1 6117 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMB1 5689 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, MINT, YeastHigh, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast;
int.Mint: MI:0915(physical association)
RBX1 9978 PPIE 10450 pd <> reg.ITFP.txt: no annot
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
TREX1 11277 DDX51 317781 pd <> reg.ITFP.txt: no annot
PSMA1 5682 PSMB3 5691 pp -- int.Intact: MI:0914(association);
int.I2D: IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Yeast, YeastHigh, BioGrid_Yeast
EIF6 3692 OGDH 4967 pp -- int.I2D: YeastLow
PSMA1 5682 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastMedium
PPP2R1A 5518 PSMA3 5684 pp -- int.I2D: YeastLow, IntAct_Mouse
RPSA 3921 VARS 7407 pp -- int.I2D: IntAct_Yeast
PSMD3 5709 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
EIF6 3692 PGD 5226 pp -- int.I2D: YeastLow
PSMD1 5707 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast
PPP2R1A 5518 RUVBL1 8607 pp -- int.I2D: YeastLow
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMA1 5682 PSMA2 5683 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
RPSA 3921 RAN 5901 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
PSMD6 9861 RUVBL2 10856 pp -- int.I2D: YeastLow
TUBG1 7283 VARS 7407 pd < reg.ITFP.txt: no annot
CSE1L 1434 RPA1 6117 pd < reg.ITFP.txt: no annot
ACTB 60 PSMA3 5684 pp -- int.I2D: BioGrid, BioGrid_Yeast
OGDH 4967 PSMD6 9861 pp -- int.I2D: YeastLow
RUVBL1 8607 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
RUVBL1 8607 RUVBL2 10856 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid, BioGrid_Mouse, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct, IntAct_Fly, IntAct_Worm, IntAct_Yeast, INTEROLOG, MINT_Worm, MINT_Yeast, BCI, BioGrid_Fly, BIND_Fly, BIND_Worm, FlyHigh, INNATEDB, Krogan_Core, MIPS, YeastHigh, Yu_GoldStd;
int.Ravasi: -;
int.HPRD: in vitro, in vivo, yeast 2-hybrid;
int.DIP: MI:0915(physical association)
OGDH 4967 RB1 5925 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, BioGrid, YeastMedium
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
MTHFD1 4522 PRMT3 10196 pd < reg.ITFP.txt: no annot
PPP2R1A 5518 PSMB2 5690 pp -- int.I2D: IntAct_Mouse
ACTB 60 PPP2R1A 5518 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
ACTB 60 CAD 790 pp -- int.I2D: IntAct_Yeast
OGDH 4967 PGD 5226 pp -- int.I2D: YeastLow
PSMD1 5707 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMD1 5707 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast
CASP8 841 MAPT 4137 pp -- int.I2D: BCI;
int.HPRD: in vitro, in vivo
PSMA1 5682 RPA1 6117 pd < reg.ITFP.txt: no annot
PSMB7 5695 RBX1 9978 pd < reg.ITFP.txt: no annot
PSMA3 5684 RUVBL2 10856 pp -- int.I2D: YeastLow
CAD 790 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PGD 5226 PSMD11 5717 pp -- int.I2D: YeastLow
HNRNPC 3183 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMD3 5709 RUVBL2 10856 pp -- int.I2D: YeastLow
VARS 7407 POLE4 56655 pd <> reg.ITFP.txt: no annot
PSMA2 5683 PSMB3 5691 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd
PSMD3 5709 TUBG1 7283 pd > reg.ITFP.txt: no annot
PPP2R1A 5518 PSMB7 5695 pp -- int.I2D: IntAct_Mouse
PSMD11 5717 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, IntAct, INTEROLOG
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RB1 5925 pd < reg.ITFP.txt: no annot
CAD 790 DDX51 317781 pp -- int.I2D: IntAct_Yeast
VARS 7407 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
HNRNPC 3183 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMA5 5686 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastHigh, Yu_GoldStd, Krogan_Core, MINT_Yeast
CSE1L 1434 RPSA 3921 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA2 5683 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMB7 5695 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastLow, IntAct, Krogan_Core, MINT_Yeast, Yu_GoldStd;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
VARS 7407 RUVBL1 8607 pd <> reg.ITFP.txt: no annot
PSMA3 5684 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow
PSMD1 5707 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, IntAct, Krogan_Core
PSMA3 5684 PSMD1 5707 pp -- int.I2D: BioGrid, BioGrid_Yeast
PSMA5 5686 PSMB3 5691 pp -- int.I2D: BioGrid_Yeast, YeastHigh
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 EFTUD2 9343 pp -- int.I2D: BioGrid
PSMB2 5690 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CCNA2 890 RB1 5925 pp -- int.I2D: IntAct
OGDH 4967 PSMD14 10213 pp -- int.I2D: YeastLow
PGD 5226 PSMD3 5709 pp -- int.I2D: YeastLow
PSMB7 5695 DDX51 317781 pd < reg.ITFP.txt: no annot
PSMB7 5695 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, MINT_Yeast, YeastLow, Krogan_Core
MTHFD1 4522 RUVBL1 8607 pd < reg.ITFP.txt: no annot
MTHFD1 4522 VARS 7407 pd < reg.ITFP.txt: no annot
MTHFD1 4522 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
PSMD3 5709 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, IntAct, IntAct_Yeast, MINT_Worm, MINT_Yeast, YeastHigh, BioGrid, BIND_Yeast, IntAct_Worm, INTEROLOG, Krogan_Core, MIPS
PPP2R1A 5518 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMA5 5686 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
TUBG1 7283 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 RUVBL1 8607 pp -- int.I2D: BioGrid
PSMB7 5695 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RAN 5901 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, NON_CORE
RAN 5901 VARS 7407 pd < reg.ITFP.txt: no annot
TUBG1 7283 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMD6 9861 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh
POLR2F 5435 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 RAN 5901 pp -- int.I2D: IntAct_Yeast
PSMB3 5691 PSMB7 5695 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, YeastHigh, HPRD, Krogan_Core, MINT_Yeast, MIPS;
int.HPRD: yeast 2-hybrid
ACTB 60 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
MTHFD1 4522 RPA1 6117 pd < reg.ITFP.txt: no annot
VARS 7407 DDX51 317781 pd <> reg.ITFP.txt: no annot
RUVBL1 8607 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMD3 5709 VARS 7407 pd <> reg.ITFP.txt: no annot
PGD 5226 PPP2R1A 5518 pp -- int.I2D: YeastLow
PSMB7 5695 PSMD1 5707 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct
PSMA1 5682 PSMA3 5684 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, CE_DATA, HPRD, IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Worm, IntAct_Yeast, MINT_Worm, BioGrid, BioGrid_Fly, BIND_Fly, BIND_Yeast, FlyHigh, Krogan_Core, MINT_Fly, MINT_Yeast, YeastHigh, Yu_GoldStd;
int.HPRD: in vitro
PSMB7 5695 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMA2 5683 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMD11 5717 TUBG1 7283 pd > reg.ITFP.txt: no annot
PSMA2 5683 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPSA 3921 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA1 5682 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, INTEROLOG, MINT, Yu_GoldStd, BCI, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
ACTB 60 RPA2 6118 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMB1 5689 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
MTHFD1 4522 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
OGDH 4967 PSMD3 5709 pp -- int.I2D: YeastLow
PSMA5 5686 POLE4 56655 pd < reg.ITFP.txt: no annot
CAD 790 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 DDX51 317781 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct
PSMD11 5717 EFTUD2 9343 pd > reg.ITFP.txt: no annot
RUVBL1 8607 PSMD6 9861 pp -- int.I2D: YeastLow
ACTB 60 CDC16 8881 pp -- int.I2D: YeastLow
PSMD11 5717 RUVBL2 10856 pp -- int.I2D: YeastLow
OGDH 4967 PSMD11 5717 pp -- int.I2D: YeastLow
RPA1 6117 RPA2 6118 pp -- int.Intact: MI:0407(direct interaction), MI:0915(physical association);
int.I2D: HPRD, BCI, BioGrid, BIND, IntAct;
int.Transfac: -;
int.HPRD: in vitro, in vivo
PSMB3 5691 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMB1 5689 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, IntAct_Yeast, YeastHigh
VARS 7407 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
PSMA5 5686 PSMB1 5689 pp -- int.I2D: BioGrid_Yeast, BIND_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd
PSMB7 5695 PPIE 10450 pd < reg.ITFP.txt: no annot
PSMB1 5689 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMD1 5707 RUVBL2 10856 pp -- int.I2D: IntAct_Yeast
PSMA3 5684 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMB2 5690 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMA3 5684 PSMA5 5686 pp -- int.I2D: BioGrid_Yeast, BIND_Yeast, IntAct_Mouse, IntAct_Yeast, MINT_Yeast, YeastHigh, Krogan_Core, Tarassov_PCA
PSMB1 5689 TREX1 11277 pd < reg.ITFP.txt: no annot
PPP2R1A 5518 PSMA2 5683 pp -- int.I2D: IntAct_Mouse
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RB1 5925 TFRC 7037 pd > reg.ITFP.txt: no annot
ACTB 60 CSE1L 1434 pp -- int.I2D: IntAct_Yeast
PSMA3 5684 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast, YeastLow
OGDH 4967 RAN 5901 pp -- int.I2D: YeastLow
PSMB2 5690 PSMD11 5717 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB2 5690 VARS 7407 pd < reg.ITFP.txt: no annot
EIF6 3692 PSMB1 5689 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMA2 5683 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow, BioGrid
PSMB3 5691 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastLow
PSMA2 5683 PSMB1 5689 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, BCI, BioGrid, IntAct, YeastHigh
RPSA 3921 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RPA1 6117 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMD14 10213 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB3 5691 PSMD11 5717 pp -- int.I2D: YeastLow
PSMD3 5709 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, INTEROLOG, MINT_Yeast, Krogan_Core, YeastHigh
RB1 5925 PPIE 10450 pd > reg.pazar.txt: no annot
PPP2R1A 5518 PSMA5 5686 pp -- int.I2D: IntAct_Mouse
PSMB7 5695 RPA1 6117 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, MINT_Yeast, IntAct_Yeast, Krogan_Core, YeastHigh
CCNA2 890 RPA1 6117 pp -- int.I2D: BioGrid
EIF6 3692 DDX51 317781 pd < reg.ITFP.txt: no annot
EIF6 3692 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
EIF6 3692 PPP2R1A 5518 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RAN 5901 TREX1 11277 pd < reg.ITFP.txt: no annot
RUVBL2 10856 TREX1 11277 pd <> reg.ITFP.txt: no annot
CASP8 841 RB1 5925 pp -- int.I2D: BCI, BIND, HPRD;
int.HPRD: in vitro
ACTB 60 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid
CAD 790 RPSA 3921 pp -- int.I2D: IntAct_Yeast
PSMA2 5683 PSMA3 5684 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BIND_Yeast, HPRD;
int.HPRD: yeast 2-hybrid
PSMA3 5684 PSMB3 5691 pp -- int.I2D: BioGrid_Yeast, IntAct_Fly, IntAct_Yeast, YeastHigh
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
POLR2F 5435 VARS 7407 pd < reg.ITFP.txt: no annot
ACTB 60 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB2 5690 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core
ACTB 60 MAPT 4137 pp -- int.I2D: BCI;
int.HPRD: in vitro
EIF6 3692 RUVBL1 8607 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct

Related GO terms (584)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle8.56e-241.40e-196.288142465
GO:0006521regulation of cellular amino acid metabolic process2.60e-234.24e-196.559132150
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.69e-234.39e-196.181142470
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle6.30e-231.03e-186.100142474
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.70e-222.78e-186.006142579
GO:0000502proteasome complex2.28e-223.72e-186.345132258
GO:0000082G1/S transition of mitotic cell cycle5.88e-229.60e-185.2741633150
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1.17e-211.91e-176.181132265
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent6.06e-219.89e-176.013132373
GO:0000278mitotic cell cycle6.25e-211.02e-164.1882052398
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I1.28e-202.09e-165.936132377
GO:0005654nucleoplasm1.66e-192.71e-153.10626831095
GO:0002474antigen processing and presentation of peptide antigen via MHC class I2.04e-193.32e-155.648132394
GO:0016032viral process2.57e-184.19e-143.7482055540
GO:0000209protein polyubiquitination3.57e-185.83e-145.3451321116
GO:0016071mRNA metabolic process1.61e-172.63e-134.6091534223
GO:0034641cellular nitrogen compound metabolic process2.30e-173.76e-134.8421425177
GO:0005839proteasome core complex7.42e-171.21e-127.33381118
GO:0016070RNA metabolic process7.52e-171.23e-124.4611534247
GO:0042981regulation of apoptotic process1.22e-161.99e-124.9651326151
GO:0010467gene expression1.64e-162.68e-123.4392058669
GO:0004298threonine-type endopeptidase activity2.13e-163.47e-127.18181120
GO:0005829cytosol1.72e-152.81e-112.134311252562
GO:0006915apoptotic process6.19e-141.01e-093.4331734571
GO:0070062extracellular vesicular exosome1.03e-111.69e-071.96127982516
GO:0043066negative regulation of apoptotic process9.10e-111.49e-063.4451330433
GO:0044281small molecule metabolic process3.58e-105.85e-062.41219571295
GO:0022624proteasome accessory complex7.65e-101.25e-056.7375917
GO:0019773proteasome core complex, alpha-subunit complex3.50e-095.71e-057.503458
GO:0005634nucleus5.73e-089.35e-041.220311314828
GO:0005730nucleolus1.03e-061.68e-021.87217701684
GO:0016020membrane1.71e-062.79e-021.82017801746
GO:0005838proteasome regulatory particle4.23e-066.91e-026.5033712
GO:0005515protein binding4.91e-068.01e-020.922321726127
GO:0035267NuA4 histone acetyltransferase complex6.98e-061.14e-016.2803414
GO:0006281DNA repair7.18e-061.17e-013.266722264
GO:0006298mismatch repair2.16e-053.53e-015.7663620
GO:0006310DNA recombination3.40e-055.56e-014.4364467
GO:0000730DNA recombinase assembly7.39e-051.00e+007.181235
GO:0000812Swr1 complex2.06e-041.00e+006.503238
GO:0097284hepatocyte apoptotic process2.64e-041.00e+006.333229
GO:0006283transcription-coupled nucleotide-excision repair2.74e-041.00e+004.5643846
GO:0040008regulation of growth3.72e-041.00e+004.4153351
GO:0003684damaged DNA binding3.72e-041.00e+004.41531151
GO:0045651positive regulation of macrophage differentiation4.02e-041.00e+006.0432211
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding4.40e-041.00e+004.3333554
GO:0043968histone H2A acetylation4.82e-041.00e+005.9182312
GO:0000724double-strand break repair via homologous recombination5.16e-041.00e+004.2553657
GO:0005662DNA replication factor A complex5.69e-041.00e+005.8022313
GO:0030234enzyme regulator activity5.69e-041.00e+005.8022313
GO:0031011Ino80 complex6.62e-041.00e+005.6952314
GO:0042176regulation of protein catabolic process8.70e-041.00e+005.5032316
GO:0003697single-stranded DNA binding9.04e-041.00e+003.9793969
GO:0006289nucleotide-excision repair9.04e-041.00e+003.97931269
GO:0000398mRNA splicing, via spliceosome1.09e-031.00e+003.136412165
GO:0006259DNA metabolic process1.23e-031.00e+005.2552319
GO:0003678DNA helicase activity1.23e-031.00e+005.2552319
GO:0071013catalytic step 2 spliceosome1.34e-031.00e+003.7843779
GO:0031625ubiquitin protein ligase binding1.50e-031.00e+003.011413180
GO:0000718nucleotide-excision repair, DNA damage removal1.51e-031.00e+005.1102521
GO:0006297nucleotide-excision repair, DNA gap filling1.66e-031.00e+005.0432522
GO:0032201telomere maintenance via semi-conservative replication1.66e-031.00e+005.0432722
GO:0036464cytoplasmic ribonucleoprotein granule1.66e-031.00e+005.0432422
GO:0043044ATP-dependent chromatin remodeling1.81e-031.00e+004.9792423
GO:0016363nuclear matrix2.07e-031.00e+003.56431192
GO:0016605PML body2.07e-031.00e+003.5643592
GO:0006611protein export from nucleus2.14e-031.00e+004.8592425
GO:0005200structural constituent of cytoskeleton2.14e-031.00e+003.5483793
GO:0000722telomere maintenance via recombination2.32e-031.00e+004.8022726
GO:0071339MLL1 complex2.50e-031.00e+004.7482327
GO:0043022ribosome binding2.68e-031.00e+004.6952328
GO:0043967histone H4 acetylation2.68e-031.00e+004.6952328
GO:0031492nucleosomal DNA binding2.68e-031.00e+004.6952428
GO:0070243regulation of thymocyte apoptotic process2.76e-031.00e+008.503111
GO:0004088carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity2.76e-031.00e+008.503111
GO:0034602oxoglutarate dehydrogenase (NAD+) activity2.76e-031.00e+008.503111
GO:0030690Noc1p-Noc2p complex2.76e-031.00e+008.503111
GO:0090230regulation of centromere complex assembly2.76e-031.00e+008.503111
GO:0070262peptidyl-serine dephosphorylation2.76e-031.00e+008.503111
GO:0004632phosphopantothenate--cysteine ligase activity2.76e-031.00e+008.503111
GO:0019521D-gluconate metabolic process2.76e-031.00e+008.503111
GO:0070335aspartate binding2.76e-031.00e+008.503111
GO:0008262importin-alpha export receptor activity2.76e-031.00e+008.503111
GO:0008541proteasome regulatory particle, lid subcomplex2.76e-031.00e+008.503111
GO:0032558adenyl deoxyribonucleotide binding2.76e-031.00e+008.503111
GO:0004151dihydroorotase activity2.76e-031.00e+008.503111
GO:0000054ribosomal subunit export from nucleus2.76e-031.00e+008.503111
GO:0004070aspartate carbamoyltransferase activity2.76e-031.00e+008.503111
GO:0004486methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity2.76e-031.00e+008.503111
GO:0006271DNA strand elongation involved in DNA replication3.29e-031.00e+004.5482931
GO:0007067mitotic nuclear division3.70e-031.00e+002.651413231
GO:0008380RNA splicing3.75e-031.00e+002.645413232
GO:0030529ribonucleoprotein complex3.80e-031.00e+003.25538114
GO:0006325chromatin organization4.71e-031.00e+003.14534123
GO:0050681androgen receptor binding4.91e-031.00e+004.2552438
GO:0006260DNA replication4.92e-031.00e+003.122312125
GO:0006284base-excision repair5.16e-031.00e+004.2172739
GO:0045252oxoglutarate dehydrogenase complex5.51e-031.00e+007.503122
GO:0097286iron ion import5.51e-031.00e+007.503112
GO:0006407rRNA export from nucleus5.51e-031.00e+007.503112
GO:0061034olfactory bulb mitral cell layer development5.51e-031.00e+007.503112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)5.51e-031.00e+007.503112
GO:0019322pentose biosynthetic process5.51e-031.00e+007.503112
GO:0004832valine-tRNA ligase activity5.51e-031.00e+007.503112
GO:0006438valyl-tRNA aminoacylation5.51e-031.00e+007.503112
GO:0000105histidine biosynthetic process5.51e-031.00e+007.503112
GO:00082963'-5'-exodeoxyribonuclease activity5.51e-031.00e+007.503112
GO:0004998transferrin receptor activity5.51e-031.00e+007.503112
GO:0097199cysteine-type endopeptidase activity involved in apoptotic signaling pathway5.51e-031.00e+007.503112
GO:0031134sister chromatid biorientation5.51e-031.00e+007.503112
GO:0005055laminin receptor activity5.51e-031.00e+007.503112
GO:0007070negative regulation of transcription from RNA polymerase II promoter during mitosis5.51e-031.00e+007.503122
GO:0070409carbamoyl phosphate biosynthetic process5.51e-031.00e+007.503112
GO:0030521androgen receptor signaling pathway5.69e-031.00e+004.1452241
GO:0032508DNA duplex unwinding5.97e-031.00e+004.1102442
GO:0000086G2/M transition of mitotic cell cycle6.35e-031.00e+002.99037137
GO:0016887ATPase activity7.28e-031.00e+002.91837144
GO:0006921cellular component disassembly involved in execution phase of apoptosis7.43e-031.00e+003.9482547
GO:0006457protein folding7.99e-031.00e+002.86838149
GO:0004591oxoglutarate dehydrogenase (succinyl-transferring) activity8.25e-031.00e+006.918113
GO:0031113regulation of microtubule polymerization8.25e-031.00e+006.918113
GO:0004616phosphogluconate dehydrogenase (decarboxylating) activity8.25e-031.00e+006.918113
GO:0071459protein localization to chromosome, centromeric region8.25e-031.00e+006.918113
GO:0009051pentose-phosphate shunt, oxidative branch8.25e-031.00e+006.918113
GO:0044205'de novo' UMP biosynthetic process8.25e-031.00e+006.918113
GO:0071930negative regulation of transcription involved in G1/S transition of mitotic cell cycle8.25e-031.00e+006.918113
GO:0060632regulation of microtubule-based movement8.25e-031.00e+006.918113
GO:0036462TRAIL-activated apoptotic signaling pathway8.25e-031.00e+006.918113
GO:0022028tangential migration from the subventricular zone to the olfactory bulb8.25e-031.00e+006.918113
GO:0071899negative regulation of estrogen receptor binding8.25e-031.00e+006.918113
GO:0071733transcriptional activation by promoter-enhancer looping8.25e-031.00e+006.918113
GO:0060715syncytiotrophoblast cell differentiation involved in labyrinthine layer development8.25e-031.00e+006.918113
GO:0000056ribosomal small subunit export from nucleus8.25e-031.00e+006.918113
GO:0045298tubulin complex8.25e-031.00e+006.918113
GO:0006207'de novo' pyrimidine nucleobase biosynthetic process8.25e-031.00e+006.918113
GO:0031100organ regeneration8.37e-031.00e+003.8592450
GO:0000226microtubule cytoskeleton organization1.01e-021.00e+003.7212355
GO:003068690S preribosome1.10e-021.00e+006.503114
GO:0071922regulation of cohesin localization to chromatin1.10e-021.00e+006.503114
GO:0019788NEDD8 ligase activity1.10e-021.00e+006.503114
GO:0016274protein-arginine N-methyltransferase activity1.10e-021.00e+006.503114
GO:0004488methylenetetrahydrofolate dehydrogenase (NADP+) activity1.10e-021.00e+006.503114
GO:0004329formate-tetrahydrofolate ligase activity1.10e-021.00e+006.503114
GO:0042802identical protein binding1.10e-021.00e+001.885518491
GO:0032387negative regulation of intracellular transport1.10e-021.00e+006.503114
GO:0043141ATP-dependent 5'-3' DNA helicase activity1.10e-021.00e+006.503114
GO:0004477methenyltetrahydrofolate cyclohydrolase activity1.10e-021.00e+006.503114
GO:0043550regulation of lipid kinase activity1.10e-021.00e+006.503114
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)1.10e-021.00e+006.503114
GO:0000212meiotic spindle organization1.10e-021.00e+006.503114
GO:0034969histone arginine methylation1.10e-021.00e+006.503114
GO:0035877death effector domain binding1.10e-021.00e+006.503114
GO:0006104succinyl-CoA metabolic process1.10e-021.00e+006.503114
GO:0006543glutamine catabolic process1.10e-021.00e+006.503114
GO:0009396folic acid-containing compound biosynthetic process1.10e-021.00e+006.503114
GO:0031467Cul7-RING ubiquitin ligase complex1.10e-021.00e+006.503114
GO:0000055ribosomal large subunit export from nucleus1.10e-021.00e+006.503114
GO:0035189Rb-E2F complex1.10e-021.00e+006.503114
GO:0034088maintenance of mitotic sister chromatid cohesion1.10e-021.00e+006.503114
GO:0034349glial cell apoptotic process1.10e-021.00e+006.503114
GO:0008853exodeoxyribonuclease III activity1.10e-021.00e+006.503114
GO:0000723telomere maintenance1.15e-021.00e+003.6202859
GO:0032481positive regulation of type I interferon production1.23e-021.00e+003.5722661
GO:0006302double-strand break repair1.27e-021.00e+003.5482862
GO:0042256mature ribosome assembly1.37e-021.00e+006.181115
GO:0001940male pronucleus1.37e-021.00e+006.181115
GO:0032407MutSalpha complex binding1.37e-021.00e+006.181115
GO:2000001regulation of DNA damage checkpoint1.37e-021.00e+006.181115
GO:0071813lipoprotein particle binding1.37e-021.00e+006.181115
GO:0043248proteasome assembly1.37e-021.00e+006.181115
GO:0048667cell morphogenesis involved in neuron differentiation1.37e-021.00e+006.181115
GO:0030891VCB complex1.37e-021.00e+006.181125
GO:0005827polar microtubule1.37e-021.00e+006.181115
GO:0006734NADH metabolic process1.37e-021.00e+006.181115
GO:0061133endopeptidase activator activity1.37e-021.00e+006.181115
GO:0051414response to cortisol1.37e-021.00e+006.181115
GO:0031465Cul4B-RING E3 ubiquitin ligase complex1.37e-021.00e+006.181125
GO:0019932second-messenger-mediated signaling1.37e-021.00e+006.181115
GO:0097153cysteine-type endopeptidase activity involved in apoptotic process1.37e-021.00e+006.181115
GO:0009086methionine biosynthetic process1.37e-021.00e+006.181115
GO:0042518negative regulation of tyrosine phosphorylation of Stat3 protein1.37e-021.00e+006.181115
GO:0008622epsilon DNA polymerase complex1.37e-021.00e+006.181115
GO:0031461cullin-RING ubiquitin ligase complex1.37e-021.00e+006.181115
GO:0071169establishment of protein localization to chromatin1.37e-021.00e+006.181115
GO:0005638lamin filament1.37e-021.00e+006.181115
GO:0030976thiamine pyrophosphate binding1.37e-021.00e+006.181115
GO:0032025response to cobalt ion1.37e-021.00e+006.181115
GO:0005737cytoplasm1.46e-021.00e+000.71518983976
GO:0006338chromatin remodeling1.51e-021.00e+003.4152468
GO:0043353enucleate erythrocyte differentiation1.64e-021.00e+005.918116
GO:0021695cerebellar cortex development1.64e-021.00e+005.918116
GO:0031264death-inducing signaling complex1.64e-021.00e+005.918116
GO:0046134pyrimidine nucleoside biosynthetic process1.64e-021.00e+005.918116
GO:0009108coenzyme biosynthetic process1.64e-021.00e+005.918116
GO:0045842positive regulation of mitotic metaphase/anaphase transition1.64e-021.00e+005.918116
GO:0021860pyramidal neuron development1.64e-021.00e+005.918116
GO:0043023ribosomal large subunit binding1.64e-021.00e+005.918126
GO:0031466Cul5-RING ubiquitin ligase complex1.64e-021.00e+005.918116
GO:0031265CD95 death-inducing signaling complex1.64e-021.00e+005.918116
GO:0030957Tat protein binding1.64e-021.00e+005.918146
GO:0032405MutLalpha complex binding1.64e-021.00e+005.918126
GO:0008469histone-arginine N-methyltransferase activity1.64e-021.00e+005.918116
GO:0032355response to estradiol1.73e-021.00e+003.3132573
GO:0000785chromatin1.73e-021.00e+003.3132573
GO:0007265Ras protein signal transduction1.82e-021.00e+003.2742375
GO:0006767water-soluble vitamin metabolic process1.82e-021.00e+003.2742375
GO:0003924GTPase activity1.83e-021.00e+002.42239203
GO:0060546negative regulation of necroptotic process1.91e-021.00e+005.695117
GO:0031462Cul2-RING ubiquitin ligase complex1.91e-021.00e+005.695127
GO:0035999tetrahydrofolate interconversion1.91e-021.00e+005.695117
GO:0010950positive regulation of endopeptidase activity1.91e-021.00e+005.695117
GO:0000028ribosomal small subunit assembly1.91e-021.00e+005.695117
GO:0002161aminoacyl-tRNA editing activity1.91e-021.00e+005.695127
GO:0035242protein-arginine omega-N asymmetric methyltransferase activity1.91e-021.00e+005.695117
GO:0001939female pronucleus1.91e-021.00e+005.695117
GO:0097342ripoptosome1.91e-021.00e+005.695117
GO:0072341modified amino acid binding1.91e-021.00e+005.695117
GO:0000930gamma-tubulin complex1.91e-021.00e+005.695117
GO:0019919peptidyl-arginine methylation, to asymmetrical-dimethyl arginine1.91e-021.00e+005.695117
GO:0016018cyclosporin A binding1.91e-021.00e+005.695117
GO:0006766vitamin metabolic process1.95e-021.00e+003.2172378
GO:0097202activation of cysteine-type endopeptidase activity2.19e-021.00e+005.503118
GO:0006554lysine catabolic process2.19e-021.00e+005.503128
GO:0045116protein neddylation2.19e-021.00e+005.503128
GO:0000800lateral element2.19e-021.00e+005.503118
GO:0031464Cul4A-RING E3 ubiquitin ligase complex2.19e-021.00e+005.503128
GO:0001055RNA polymerase II activity2.19e-021.00e+005.503138
GO:0070688MLL5-L complex2.19e-021.00e+005.503118
GO:0006164purine nucleotide biosynthetic process2.19e-021.00e+005.503128
GO:0005681spliceosomal complex2.20e-021.00e+003.1282383
GO:0006184GTP catabolic process2.26e-021.00e+002.30639220
GO:0015937coenzyme A biosynthetic process2.45e-021.00e+005.333119
GO:0010389regulation of G2/M transition of mitotic cell cycle2.45e-021.00e+005.333119
GO:0000075cell cycle checkpoint2.45e-021.00e+005.333129
GO:0048699generation of neurons2.45e-021.00e+005.333119
GO:0014075response to amine2.45e-021.00e+005.333119
GO:0006228UTP biosynthetic process2.45e-021.00e+005.333119
GO:0047497mitochondrion transport along microtubule2.45e-021.00e+005.333129
GO:0031000response to caffeine2.45e-021.00e+005.333129
GO:0042470melanosome2.66e-021.00e+002.97921092
GO:0044822poly(A) RNA binding2.70e-021.00e+001.2367501078
GO:0070628proteasome binding2.72e-021.00e+005.1811110
GO:0046655folic acid metabolic process2.72e-021.00e+005.1811110
GO:0015939pantothenate metabolic process2.72e-021.00e+005.1811110
GO:0006450regulation of translational fidelity2.72e-021.00e+005.1811210
GO:0008088axon cargo transport2.72e-021.00e+005.1811110
GO:0007084mitotic nuclear envelope reassembly2.72e-021.00e+005.1811110
GO:0021756striatum development2.72e-021.00e+005.1811110
GO:2001239regulation of extrinsic apoptotic signaling pathway in absence of ligand2.99e-021.00e+005.0431111
GO:0042551neuron maturation2.99e-021.00e+005.0431211
GO:0045120pronucleus2.99e-021.00e+005.0431111
GO:0031116positive regulation of microtubule polymerization2.99e-021.00e+005.0431211
GO:0035458cellular response to interferon-beta2.99e-021.00e+005.0431211
GO:0006098pentose-phosphate shunt2.99e-021.00e+005.0431311
GO:0010569regulation of double-strand break repair via homologous recombination2.99e-021.00e+005.0431111
GO:0031571mitotic G1 DNA damage checkpoint2.99e-021.00e+005.0431311
GO:0001054RNA polymerase I activity2.99e-021.00e+005.0431311
GO:0033762response to glucagon2.99e-021.00e+005.0431111
GO:0001841neural tube formation2.99e-021.00e+005.0431111
GO:0061136regulation of proteasomal protein catabolic process3.26e-021.00e+004.9181112
GO:00709353'-UTR-mediated mRNA stabilization3.26e-021.00e+004.9181212
GO:0051146striated muscle cell differentiation3.26e-021.00e+004.9181112
GO:0005736DNA-directed RNA polymerase I complex3.26e-021.00e+004.9181312
GO:0021794thalamus development3.26e-021.00e+004.9181112
GO:0006275regulation of DNA replication3.26e-021.00e+004.9181212
GO:0030111regulation of Wnt signaling pathway3.26e-021.00e+004.9181112
GO:0034399nuclear periphery3.26e-021.00e+004.9181112
GO:0042273ribosomal large subunit biogenesis3.53e-021.00e+004.8021413
GO:0032479regulation of type I interferon production3.53e-021.00e+004.8021213
GO:0045780positive regulation of bone resorption3.53e-021.00e+004.8021113
GO:0000738DNA catabolic process, exonucleolytic3.53e-021.00e+004.8021213
GO:0008266poly(U) RNA binding3.53e-021.00e+004.8021113
GO:0005815microtubule organizing center3.69e-021.00e+002.72124110
GO:0034185apolipoprotein binding3.79e-021.00e+004.6951114
GO:0007020microtubule nucleation3.79e-021.00e+004.6951114
GO:0007095mitotic G2 DNA damage checkpoint3.79e-021.00e+004.6951114
GO:0015630microtubule cytoskeleton3.82e-021.00e+002.69525112
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay3.94e-021.00e+002.670210114
GO:0005819spindle3.94e-021.00e+002.67027114
GO:0019058viral life cycle4.00e-021.00e+002.657210115
GO:0030225macrophage differentiation4.06e-021.00e+004.5961115
GO:0005671Ada2/Gcn5/Ada3 transcription activator complex4.06e-021.00e+004.5961115
GO:0016514SWI/SNF complex4.06e-021.00e+004.5961315
GO:0005123death receptor binding4.06e-021.00e+004.5961115
GO:0006672ceramide metabolic process4.06e-021.00e+004.5961115
GO:0045445myoblast differentiation4.06e-021.00e+004.5961215
GO:2001241positive regulation of extrinsic apoptotic signaling pathway in absence of ligand4.06e-021.00e+004.5961215
GO:0035066positive regulation of histone acetylation4.06e-021.00e+004.5961115
GO:0006261DNA-dependent DNA replication4.06e-021.00e+004.5961215
GO:0072562blood microparticle4.07e-021.00e+002.64524116
GO:0030101natural killer cell activation4.32e-021.00e+004.5031116
GO:0050998nitric-oxide synthase binding4.32e-021.00e+004.5031116
GO:0001056RNA polymerase III activity4.32e-021.00e+004.5031316
GO:0005665DNA-directed RNA polymerase II, core complex4.32e-021.00e+004.5031416
GO:0051603proteolysis involved in cellular protein catabolic process4.32e-021.00e+004.5031216
GO:0001673male germ cell nucleus4.32e-021.00e+004.5031116
GO:00061032-oxoglutarate metabolic process4.32e-021.00e+004.5031116
GO:00084083'-5' exonuclease activity4.32e-021.00e+004.5031216
GO:0019899enzyme binding4.48e-021.00e+001.918311288
GO:0075733intracellular transport of virus4.59e-021.00e+004.4151217
GO:0010243response to organonitrogen compound4.59e-021.00e+004.4151217
GO:0005666DNA-directed RNA polymerase III complex4.59e-021.00e+004.4151317
GO:0045070positive regulation of viral genome replication4.59e-021.00e+004.4151117
GO:0007126meiotic nuclear division4.59e-021.00e+004.4151117
GO:0006511ubiquitin-dependent protein catabolic process4.79e-021.00e+002.51425127
GO:0071392cellular response to estradiol stimulus4.85e-021.00e+004.3331118
GO:0031122cytoplasmic microtubule organization4.85e-021.00e+004.3331218
GO:0035861site of double-strand break4.85e-021.00e+004.3331118
GO:0045773positive regulation of axon extension4.85e-021.00e+004.3331218
GO:0070536protein K63-linked deubiquitination4.85e-021.00e+004.3331118
GO:0006386termination of RNA polymerase III transcription4.85e-021.00e+004.3331318
GO:0006541glutamine metabolic process4.85e-021.00e+004.3331118
GO:0006385transcription elongation from RNA polymerase III promoter4.85e-021.00e+004.3331318
GO:0006303double-strand break repair via nonhomologous end joining4.85e-021.00e+004.3331318
GO:0043234protein complex4.95e-021.00e+001.859317300
GO:0006413translational initiation5.06e-021.00e+002.469212131
GO:0006200ATP catabolic process5.07e-021.00e+001.844314303
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process5.11e-021.00e+004.2551119
GO:0007088regulation of mitosis5.11e-021.00e+004.2551119
GO:0048863stem cell differentiation5.11e-021.00e+004.2551119
GO:0000790nuclear chromatin5.20e-021.00e+002.44727133
GO:2000134negative regulation of G1/S transition of mitotic cell cycle5.38e-021.00e+004.1811220
GO:0048873homeostasis of number of cells within a tissue5.38e-021.00e+004.1811120
GO:0005719nuclear euchromatin5.38e-021.00e+004.1811220
GO:0000159protein phosphatase type 2A complex5.38e-021.00e+004.1811220
GO:0097194execution phase of apoptosis5.38e-021.00e+004.1811120
GO:0008601protein phosphatase type 2A regulator activity5.38e-021.00e+004.1811320
GO:0005680anaphase-promoting complex5.38e-021.00e+004.1811420
GO:0045862positive regulation of proteolysis5.64e-021.00e+004.1101121
GO:0045595regulation of cell differentiation5.64e-021.00e+004.1101121
GO:0071364cellular response to epidermal growth factor stimulus5.64e-021.00e+004.1101121
GO:0048675axon extension5.64e-021.00e+004.1101121
GO:0007507heart development5.76e-021.00e+002.36325141
GO:0019901protein kinase binding5.79e-021.00e+001.766321320
GO:0030316osteoclast differentiation5.90e-021.00e+004.0431222
GO:0033574response to testosterone5.90e-021.00e+004.0431222
GO:0000083regulation of transcription involved in G1/S transition of mitotic cell cycle5.90e-021.00e+004.0431322
GO:0030863cortical cytoskeleton5.90e-021.00e+004.0431122
GO:0007052mitotic spindle organization5.90e-021.00e+004.0431222
GO:0005525GTP binding6.15e-021.00e+001.730311328
GO:0010506regulation of autophagy6.16e-021.00e+003.9791123
GO:0031463Cul3-RING ubiquitin ligase complex6.16e-021.00e+003.9791223
GO:0043236laminin binding6.16e-021.00e+003.9791123
GO:0045879negative regulation of smoothened signaling pathway6.16e-021.00e+003.9791123
GO:0006513protein monoubiquitination6.16e-021.00e+003.9791123
GO:0000794condensed nuclear chromosome6.42e-021.00e+003.9181224
GO:0006206pyrimidine nucleobase metabolic process6.42e-021.00e+003.9181224
GO:0005739mitochondrion6.59e-021.00e+001.0576241046
GO:0005813centrosome6.65e-021.00e+001.682312339
GO:0008536Ran GTPase binding6.67e-021.00e+003.8591225
GO:0070423nucleotide-binding oligomerization domain containing signaling pathway6.67e-021.00e+003.8591225
GO:0005844polysome6.67e-021.00e+003.8591425
GO:0042113B cell activation6.67e-021.00e+003.8591225
GO:0017144drug metabolic process6.67e-021.00e+003.8591125
GO:0070979protein K11-linked ubiquitination6.93e-021.00e+003.8021326
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia6.93e-021.00e+003.8021226
GO:1900740positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway6.93e-021.00e+003.8021326
GO:0006730one-carbon metabolic process6.93e-021.00e+003.8021126
GO:0004003ATP-dependent DNA helicase activity7.19e-021.00e+003.7481327
GO:2001238positive regulation of extrinsic apoptotic signaling pathway7.19e-021.00e+003.7481127
GO:0000188inactivation of MAPK activity7.19e-021.00e+003.7481127
GO:0034080CENP-A containing nucleosome assembly7.19e-021.00e+003.7481227
GO:0048565digestive tract development7.19e-021.00e+003.7481127
GO:0003723RNA binding7.41e-021.00e+001.616319355
GO:0010033response to organic substance7.45e-021.00e+003.6951228
GO:0019894kinesin binding7.45e-021.00e+003.6951128
GO:0003823antigen binding7.45e-021.00e+003.6951128
GO:0034612response to tumor necrosis factor7.45e-021.00e+003.6951228
GO:0005875microtubule associated complex7.45e-021.00e+003.6951228
GO:0005524ATP binding7.56e-021.00e+000.9077461354
GO:0006099tricarboxylic acid cycle7.70e-021.00e+003.6451329
GO:0019005SCF ubiquitin ligase complex7.70e-021.00e+003.6451129
GO:0007628adult walking behavior7.70e-021.00e+003.6451129
GO:0003730mRNA 3'-UTR binding7.70e-021.00e+003.6451229
GO:0071897DNA biosynthetic process7.70e-021.00e+003.6451229
GO:0009409response to cold7.70e-021.00e+003.6451229
GO:0003887DNA-directed DNA polymerase activity7.70e-021.00e+003.6451329
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding7.82e-021.00e+002.11025168
GO:0006360transcription from RNA polymerase I promoter7.96e-021.00e+003.5961430
GO:0007346regulation of mitotic cell cycle7.96e-021.00e+003.5961330
GO:0043124negative regulation of I-kappaB kinase/NF-kappaB signaling7.96e-021.00e+003.5961130
GO:00063707-methylguanosine mRNA capping7.96e-021.00e+003.5961430
GO:0005164tumor necrosis factor receptor binding7.96e-021.00e+003.5961330
GO:0030424axon8.14e-021.00e+002.07623172
GO:0046677response to antibiotic8.21e-021.00e+003.5481231
GO:0007093mitotic cell cycle checkpoint8.21e-021.00e+003.5481231
GO:0007094mitotic spindle assembly checkpoint8.21e-021.00e+003.5481531
GO:0050661NADP binding8.46e-021.00e+003.5031132
GO:0034644cellular response to UV8.46e-021.00e+003.5031532
GO:0033572transferrin transport8.46e-021.00e+003.5031632
GO:0031397negative regulation of protein ubiquitination8.46e-021.00e+003.5031132
GO:0051219phosphoprotein binding8.46e-021.00e+003.5031332
GO:0031072heat shock protein binding8.72e-021.00e+003.4581233
GO:0045087innate immune response8.89e-021.00e+001.236420616
GO:0003755peptidyl-prolyl cis-trans isomerase activity8.97e-021.00e+003.4151134
GO:0097110scaffold protein binding8.97e-021.00e+003.4151234
GO:0000413protein peptidyl-prolyl isomerization8.97e-021.00e+003.4151134
GO:0008625extrinsic apoptotic signaling pathway via death domain receptors8.97e-021.00e+003.4151234
GO:0005876spindle microtubule8.97e-021.00e+003.4151334
GO:0015629actin cytoskeleton9.05e-021.00e+001.98725183
GO:0032403protein complex binding9.22e-021.00e+001.97127185
GO:0034332adherens junction organization9.47e-021.00e+003.3331136
GO:0004221ubiquitin thiolesterase activity9.47e-021.00e+003.3331236
GO:0051402neuron apoptotic process9.47e-021.00e+003.3331236
GO:0001895retina homeostasis9.47e-021.00e+003.3331136
GO:0046982protein heterodimerization activity9.71e-021.00e+001.447311399
GO:0008234cysteine-type peptidase activity9.72e-021.00e+003.2931237
GO:0001102RNA polymerase II activating transcription factor binding9.72e-021.00e+003.2931437
GO:0051084'de novo' posttranslational protein folding9.72e-021.00e+003.2931437
GO:0018107peptidyl-threonine phosphorylation9.72e-021.00e+003.2931137
GO:0070527platelet aggregation9.97e-021.00e+003.2551238
GO:0097191extrinsic apoptotic signaling pathway9.97e-021.00e+003.2551238
GO:0008026ATP-dependent helicase activity1.02e-011.00e+003.2171339
GO:0006096glycolytic process1.02e-011.00e+003.2171439
GO:0032092positive regulation of protein binding1.02e-011.00e+003.2171339
GO:0021766hippocampus development1.02e-011.00e+003.2171439
GO:0006383transcription from RNA polymerase III promoter1.02e-011.00e+003.2171339
GO:0031490chromatin DNA binding1.02e-011.00e+003.2171239
GO:0071407cellular response to organic cyclic compound1.02e-011.00e+003.2171239
GO:0022627cytosolic small ribosomal subunit1.02e-011.00e+003.2171339
GO:0007595lactation1.02e-011.00e+003.2171239
GO:0000781chromosome, telomeric region1.05e-011.00e+003.1811240
GO:0005930axoneme1.07e-011.00e+003.1451141
GO:0043195terminal bouton1.07e-011.00e+003.1451141
GO:0004722protein serine/threonine phosphatase activity1.10e-011.00e+003.1101142
GO:0030155regulation of cell adhesion1.10e-011.00e+003.1101342
GO:0006418tRNA aminoacylation for protein translation1.10e-011.00e+003.1101542
GO:0035914skeletal muscle cell differentiation1.10e-011.00e+003.1101142
GO:0042110T cell activation1.12e-011.00e+003.0761343
GO:0014070response to organic cyclic compound1.12e-011.00e+003.0761343
GO:0035872nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway1.12e-011.00e+003.0761243
GO:0007286spermatid development1.15e-011.00e+003.0431144
GO:0048146positive regulation of fibroblast proliferation1.15e-011.00e+003.0431244
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding1.15e-011.00e+003.0431244
GO:0050434positive regulation of viral transcription1.15e-011.00e+003.0431544
GO:0015030Cajal body1.17e-011.00e+003.0111245
GO:0043966histone H3 acetylation1.17e-011.00e+003.0111245
GO:0044297cell body1.19e-011.00e+002.9791246
GO:0021762substantia nigra development1.19e-011.00e+002.9791146
GO:0001047core promoter binding1.19e-011.00e+002.9791246
GO:0000079regulation of cyclin-dependent protein serine/threonine kinase activity1.22e-011.00e+002.9481347
GO:0019003GDP binding1.24e-011.00e+002.9181248
GO:0003743translation initiation factor activity1.27e-011.00e+002.8881449
GO:0035690cellular response to drug1.29e-011.00e+002.8591250
GO:0006091generation of precursor metabolites and energy1.32e-011.00e+002.8301351
GO:0005905coated pit1.32e-011.00e+002.8301251
GO:0000775chromosome, centromeric region1.34e-011.00e+002.8021252
GO:0008168methyltransferase activity1.34e-011.00e+002.8021152
GO:0004197cysteine-type endopeptidase activity1.34e-011.00e+002.8021252
GO:0003725double-stranded RNA binding1.39e-011.00e+002.7481654
GO:0090305nucleic acid phosphodiester bond hydrolysis1.39e-011.00e+002.7481254
GO:0019900kinase binding1.39e-011.00e+002.7481154
GO:0050680negative regulation of epithelial cell proliferation1.39e-011.00e+002.7481154
GO:0097193intrinsic apoptotic signaling pathway1.41e-011.00e+002.7211455
GO:0008233peptidase activity1.41e-011.00e+002.7211355
GO:0003713transcription coactivator activity1.41e-011.00e+001.602210239
GO:0000932cytoplasmic mRNA processing body1.43e-011.00e+002.6951356
GO:0051291protein heterooligomerization1.46e-011.00e+002.6701157
GO:0006879cellular iron ion homeostasis1.46e-011.00e+002.6701557
GO:0030097hemopoiesis1.48e-011.00e+002.6451358
GO:0008237metallopeptidase activity1.48e-011.00e+002.6451158
GO:0045893positive regulation of transcription, DNA-templated1.50e-011.00e+001.160317487
GO:0051087chaperone binding1.51e-011.00e+002.6201659
GO:0045216cell-cell junction organization1.51e-011.00e+002.6201259
GO:0005643nuclear pore1.51e-011.00e+002.6201459
GO:0005840ribosome1.51e-011.00e+002.6201259
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity1.51e-011.00e+002.6201459
GO:0031966mitochondrial membrane1.51e-011.00e+002.6201159
GO:0019903protein phosphatase binding1.60e-011.00e+002.5251463
GO:0042995cell projection1.60e-011.00e+002.5251663
GO:0007059chromosome segregation1.62e-011.00e+002.5031364
GO:0006469negative regulation of protein kinase activity1.65e-011.00e+002.4801265
GO:0001558regulation of cell growth1.67e-011.00e+002.4581466
GO:0071260cellular response to mechanical stimulus1.67e-011.00e+002.4581466
GO:0006368transcription elongation from RNA polymerase II promoter1.69e-011.00e+002.4361667
GO:0000166nucleotide binding1.72e-011.00e+001.41526272
GO:0034329cell junction assembly1.78e-011.00e+002.3531171
GO:0055037recycling endosome1.83e-011.00e+002.3131273
GO:0055086nucleobase-containing small molecule metabolic process1.83e-011.00e+002.3131573
GO:0031175neuron projection development1.87e-011.00e+002.2741175
GO:0035666TRIF-dependent toll-like receptor signaling pathway1.90e-011.00e+002.2551276
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process1.90e-011.00e+002.2551376
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis1.92e-011.00e+002.2361577
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process1.92e-011.00e+002.2361677
GO:0002756MyD88-independent toll-like receptor signaling pathway1.94e-011.00e+002.2171278
GO:0006334nucleosome assembly1.96e-011.00e+002.1991479
GO:0034138toll-like receptor 3 signaling pathway1.99e-011.00e+002.1811280
GO:0007565female pregnancy1.99e-011.00e+002.1811280
GO:0019083viral transcription2.01e-011.00e+002.1631881
GO:0001889liver development2.03e-011.00e+002.1451382
GO:0005856cytoskeleton2.11e-011.00e+001.22228311
GO:0047485protein N-terminus binding2.12e-011.00e+002.0761486
GO:0006898receptor-mediated endocytosis2.12e-011.00e+002.0761286
GO:0006415translational termination2.14e-011.00e+002.0601887
GO:0045471response to ethanol2.16e-011.00e+002.0431188
GO:0003690double-stranded DNA binding2.23e-011.00e+001.9951491
GO:0006928cellular component movement2.25e-011.00e+001.9791792
GO:0006414translational elongation2.27e-011.00e+001.96311193
GO:0001649osteoblast differentiation2.31e-011.00e+001.9331695
GO:0051082unfolded protein binding2.31e-011.00e+001.9331695
GO:0008283cell proliferation2.32e-011.00e+001.132212331
GO:0043231intracellular membrane-bounded organelle2.33e-011.00e+001.12828332
GO:0034142toll-like receptor 4 signaling pathway2.33e-011.00e+001.9181296
GO:0001764neuron migration2.33e-011.00e+001.9181296
GO:0006364rRNA processing2.33e-011.00e+001.9181596
GO:0003682chromatin binding2.35e-011.00e+001.119212334
GO:0030426growth cone2.36e-011.00e+001.9031397
GO:0071456cellular response to hypoxia2.38e-011.00e+001.8881498
GO:0006470protein dephosphorylation2.40e-011.00e+001.8731199
GO:0006614SRP-dependent cotranslational protein targeting to membrane2.50e-011.00e+001.80218104
GO:0014069postsynaptic density2.54e-011.00e+001.77511106
GO:0016023cytoplasmic membrane-bounded vesicle2.57e-011.00e+001.76113107
GO:0005741mitochondrial outer membrane2.59e-011.00e+001.74814108
GO:0002224toll-like receptor signaling pathway2.61e-011.00e+001.73412109
GO:0042127regulation of cell proliferation2.65e-011.00e+001.70814111
GO:0006461protein complex assembly2.65e-011.00e+001.70816111
GO:0030308negative regulation of cell growth2.69e-011.00e+001.68216113
GO:0017124SH3 domain binding2.73e-011.00e+001.65713115
GO:0097190apoptotic signaling pathway2.75e-011.00e+001.64514116
GO:0005635nuclear envelope2.75e-011.00e+001.64516116
GO:0044237cellular metabolic process2.79e-011.00e+001.62013118
GO:0032496response to lipopolysaccharide2.87e-011.00e+001.57214122
GO:0007219Notch signaling pathway2.93e-011.00e+001.53714125
GO:0007050cell cycle arrest2.95e-011.00e+001.52517126
GO:0009615response to virus3.06e-011.00e+001.45816132
GO:0031982vesicle3.10e-011.00e+001.436110134
GO:0006508proteolysis3.13e-011.00e+000.82329410
GO:0003735structural constituent of ribosome3.24e-011.00e+001.36318141
GO:0061024membrane organization3.33e-011.00e+001.31315146
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling3.37e-011.00e+001.29313148
GO:0008017microtubule binding3.40e-011.00e+001.27417150
GO:0046777protein autophosphorylation3.55e-011.00e+001.19913158
GO:0008543fibroblast growth factor receptor signaling pathway3.57e-011.00e+001.19014159
GO:0043005neuron projection3.60e-011.00e+001.17214161
GO:0045121membrane raft3.60e-011.00e+001.17218161
GO:0006397mRNA processing3.74e-011.00e+001.10213169
GO:0046872metal ion binding3.79e-011.00e+000.3085241465
GO:0005768endosome3.83e-011.00e+001.06015174
GO:0055114oxidation-reduction process3.84e-011.00e+000.593211481
GO:0016607nuclear speck3.85e-011.00e+001.05114175
GO:0004672protein kinase activity3.90e-011.00e+001.02712178
GO:0019904protein domain specific binding3.95e-011.00e+001.00316181
GO:0009897external side of plasma membrane3.98e-011.00e+000.98714183
GO:0044267cellular protein metabolic process3.98e-011.00e+000.551224495
GO:0006367transcription initiation from RNA polymerase II promoter4.00e-011.00e+000.97918184
GO:0001525angiogenesis4.26e-011.00e+000.85914200
GO:0001701in utero embryonic development4.42e-011.00e+000.78816210
GO:0005622intracellular4.67e-011.00e+000.68215226
GO:0005759mitochondrial matrix4.77e-011.00e+000.638112233
GO:0006412translation4.80e-011.00e+000.626115235
GO:0008134transcription factor binding4.96e-011.00e+000.56018246
GO:0043025neuronal cell body5.07e-011.00e+000.51414254
GO:0004842ubiquitin-protein transferase activity5.10e-011.00e+000.50314256
GO:0005874microtubule5.12e-011.00e+000.49116258
GO:0005975carbohydrate metabolic process5.34e-011.00e+000.40515274
GO:0006357regulation of transcription from RNA polymerase II promoter5.35e-011.00e+000.39916275
GO:0007283spermatogenesis5.36e-011.00e+000.39416276
GO:0005794Golgi apparatus5.40e-011.00e+000.158214650
GO:0007264small GTPase mediated signal transduction5.54e-011.00e+000.32313290
GO:0016567protein ubiquitination5.65e-011.00e+000.27915299
GO:0006355regulation of transcription, DNA-templated5.95e-011.00e+00-0.0213171104
GO:0007411axon guidance5.98e-011.00e+000.14919327
GO:0043565sequence-specific DNA binding6.39e-011.00e+00-0.00914365
GO:0005925focal adhesion6.44e-011.00e+00-0.029118370
GO:0007155cell adhesion6.58e-011.00e+00-0.08218384
GO:0045944positive regulation of transcription from RNA polymerase II promoter6.62e-011.00e+00-0.161219811
GO:0008284positive regulation of cell proliferation6.66e-011.00e+00-0.11218392
GO:0009986cell surface6.93e-011.00e+00-0.21919422
GO:0045892negative regulation of transcription, DNA-templated6.95e-011.00e+00-0.225114424
GO:0006366transcription from RNA polymerase II promoter6.95e-011.00e+00-0.229112425
GO:0007596blood coagulation7.27e-011.00e+00-0.355114464
GO:0055085transmembrane transport7.64e-011.00e+00-0.50318514
GO:0048471perinuclear region of cytoplasm7.70e-011.00e+00-0.528112523
GO:0005615extracellular space7.76e-011.00e+00-0.4782171010
GO:0008270zinc ion binding8.02e-011.00e+00-0.5572121067
GO:0042803protein homodimerization activity8.24e-011.00e+00-0.767111617
GO:0006351transcription, DNA-templated8.26e-011.00e+00-0.5433251585
GO:0005789endoplasmic reticulum membrane8.33e-011.00e+00-0.810110636
GO:0003700sequence-specific DNA binding transcription factor activity8.79e-011.00e+00-1.044111748
GO:0003677DNA binding8.97e-011.00e+00-0.8972261351
GO:0007165signal transduction9.33e-011.00e+00-1.389117950
GO:0005887integral component of plasma membrane9.35e-011.00e+00-1.40617961
GO:0005576extracellular region9.50e-011.00e+00-1.532191049
GO:0005886plasma membrane9.90e-011.00e+00-1.3813382834