CASP8

Genes (1)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
CASP8 841 120.8041.041141--

Gene info in the NCBI database: CASP8

12 meta-subnetworks

Subnetwork ID Size Highlighted genes
meta-reg-snw-55660 25 68
meta-reg-snw-317781 53 94
meta-reg-snw-4522 49 93
meta-reg-snw-56655 63 99
meta-reg-snw-5686 35 80
meta-reg-snw-10213 44 87
meta-reg-snw-1434 41 87
meta-int-snw-5321 9 34
meta-reg-snw-5925 31 73
meta-int-snw-4137 9 34
meta-reg-snw-11277 51 90
meta-int-snw-7431 2 14

Related GO terms (77)

Accession number Name Occurrences in all snw genes Occurrences in all int/reg genes
GO:0035877death effector domain binding14
GO:0030225macrophage differentiation115
GO:0008625extrinsic apoptotic signaling pathway via death domain receptors234
GO:0005515protein binding1726127
GO:0005737cytoplasm983976
GO:0006921cellular component disassembly involved in execution phase of apoptosis547
GO:0031625ubiquitin protein ligase binding13180
GO:0051291protein heterooligomerization157
GO:0043124negative regulation of I-kappaB kinase/NF-kappaB signaling130
GO:0034612response to tumor necrosis factor228
GO:0005829cytosol1252562
GO:0042110T cell activation343
GO:0007507heart development5141
GO:0034142toll-like receptor 4 signaling pathway296
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling3148
GO:0008233peptidase activity355
GO:0005741mitochondrial outer membrane4108
GO:0032403protein complex binding7185
GO:0045862positive regulation of proteolysis121
GO:0005739mitochondrion241046
GO:0097110scaffold protein binding234
GO:0071260cellular response to mechanical stimulus466
GO:0032496response to lipopolysaccharide4122
GO:0032025response to cobalt ion15
GO:0030101natural killer cell activation116
GO:0006508proteolysis9410
GO:0097190apoptotic signaling pathway4116
GO:0035666TRIF-dependent toll-like receptor signaling pathway276
GO:0097284hepatocyte apoptotic process29
GO:0045121membrane raft8161
GO:0097342ripoptosome17
GO:0060715syncytiotrophoblast cell differentiation involved in labyrinthine layer development13
GO:0097153cysteine-type endopeptidase activity involved in apoptotic process15
GO:0043005neuron projection4161
GO:0006915apoptotic process34571
GO:0045651positive regulation of macrophage differentiation211
GO:0044297cell body246
GO:0035872nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway243
GO:0001841neural tube formation111
GO:0002224toll-like receptor signaling pathway2109
GO:0051603proteolysis involved in cellular protein catabolic process216
GO:0036462TRAIL-activated apoptotic signaling pathway13
GO:0070423nucleotide-binding oligomerization domain containing signaling pathway225
GO:2001238positive regulation of extrinsic apoptotic signaling pathway127
GO:0046982protein heterodimerization activity11399
GO:0045471response to ethanol188
GO:0097194execution phase of apoptosis120
GO:0001525angiogenesis4200
GO:0031264death-inducing signaling complex16
GO:0097193intrinsic apoptotic signaling pathway455
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process677
GO:0008234cysteine-type peptidase activity237
GO:0060546negative regulation of necroptotic process17
GO:0005815microtubule organizing center4110
GO:0097199cysteine-type endopeptidase activity involved in apoptotic signaling pathway12
GO:0005730nucleolus701684
GO:1900740positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway326
GO:0070243regulation of thymocyte apoptotic process11
GO:0097191extrinsic apoptotic signaling pathway238
GO:0030690Noc1p-Noc2p complex11
GO:0005164tumor necrosis factor receptor binding330
GO:0004197cysteine-type endopeptidase activity252
GO:0046677response to antibiotic231
GO:0045087innate immune response20616
GO:2001239regulation of extrinsic apoptotic signaling pathway in absence of ligand111
GO:0034138toll-like receptor 3 signaling pathway280
GO:0016032viral process55540
GO:0042113B cell activation225
GO:0031265CD95 death-inducing signaling complex16
GO:0097202activation of cysteine-type endopeptidase activity18
GO:0005634nucleus1314828
GO:0005856cytoskeleton8311
GO:0071407cellular response to organic cyclic compound239
GO:0009409response to cold229
GO:0005123death receptor binding115
GO:0002756MyD88-independent toll-like receptor signaling pathway278
GO:0032355response to estradiol573