meta-int-snw-7431

Interacting subnets

Subnetwork	Dataset	Score	p-value 1	p-value 2	p-value 3	Size	Highlighted genes
reg-snw-56655	wolf-screen-ratio-mammosphere-adherent	0.828	9.29e-07	2.91e-03	5.53e-03	8	7
int-snw-7431	wolf-screen-ratio-mammosphere-adherent	0.927	3.16e-15	2.90e-03	4.49e-02	11	10

wolf-screen-ratio-mammosphere-adherent-meta-int-snw-7431 subnetwork

Genes (16)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
PSMA2	5683	112	1.093	1.106	108	Yes	-
RBX1	9978	115	1.185	0.934	148	Yes	-
PSMB7	5695	118	0.982	0.934	90	Yes	-
PSMD7	5713	15	0.640	0.958	133	Yes	-
PSMA1	5682	100	0.996	0.878	152	Yes	-
VARS	7407	86	0.549	1.002	204	Yes	-
VIM	7431	2	0.044	0.927	246	Yes	-
POLE4	56655	63	0.177	0.828	56	-	-
RPSA	3921	120	1.327	1.151	152	Yes	-
PSMB3	5691	64	0.668	0.901	19	Yes	-
RPA2	6118	96	1.250	1.151	76	Yes	-
PSMB2	5690	116	0.877	0.956	169	Yes	-
ACTB	60	134	1.153	1.151	610	Yes	-
PSMD11	5717	124	1.095	1.106	218	Yes	-
CASP8	841	12	0.804	1.041	141	-	-
KPNB1	3837	17	0.613	1.017	296	Yes	-

Interactions (48)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PSMA1	5682	PSMB2	5690	pp	--	int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid
PSMB7	5695	PSMD7	5713	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	KPNB1	3837	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
ACTB	60	PSMD7	5713	pp	--	int.I2D: BioGrid_Yeast
PSMA2	5683	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PSMB2	5690	POLE4	56655	pd	<	reg.ITFP.txt: no annot
PSMA2	5683	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
RPSA	3921	PSMD11	5717	pp	--	int.I2D: IntAct_Yeast
ACTB	60	PSMB2	5690	pp	--	int.I2D: BioGrid_Yeast
PSMA1	5682	PSMB3	5691	pp	--	int.Intact: MI:0914(association); int.I2D: IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Yeast, YeastHigh, BioGrid_Yeast
RPSA	3921	VARS	7407	pp	--	int.I2D: IntAct_Yeast
ACTB	60	RBX1	9978	pp	--	int.I2D: BioGrid_Yeast
PSMB2	5690	PSMD7	5713	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
PSMA1	5682	PSMA2	5683	pp	--	int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
PSMA1	5682	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
ACTB	60	PSMA1	5682	pp	--	int.I2D: BioGrid_Yeast
PSMB7	5695	RBX1	9978	pd	<	reg.ITFP.txt: no annot
VARS	7407	POLE4	56655	pd	<>	reg.ITFP.txt: no annot
PSMA2	5683	PSMB3	5691	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd
ACTB	60	VIM	7431	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
PSMA1	5682	PSMD7	5713	pp	--	int.I2D: BioGrid_Yeast, YeastMedium, IntAct_Yeast, MINT_Yeast
PSMB7	5695	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
KPNB1	3837	PSMA2	5683	pp	--	int.I2D: Krogan_NonCore, YeastLow
PSMA2	5683	POLE4	56655	pd	<	reg.ITFP.txt: no annot
KPNB1	3837	VIM	7431	pp	--	int.I2D: BIND_Mouse
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
PSMB7	5695	POLE4	56655	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
PSMA1	5682	VIM	7431	pp	--	int.Intact: MI:0915(physical association); int.I2D: HPRD, IntAct, BioGrid, MINT, VidalHuman_core; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid
CASP8	841	VIM	7431	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, BCI, BioGrid, HPRD, MINT, StelzlHigh; int.Mint: MI:0915(physical association); int.HPRD: in vivo
PSMD7	5713	RBX1	9978	pp	--	int.I2D: YeastLow, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast
PSMB3	5691	PSMB7	5695	pp	--	int.Intact: MI:0915(physical association); int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, YeastHigh, HPRD, Krogan_Core, MINT_Yeast, MIPS; int.HPRD: yeast 2-hybrid
ACTB	60	PSMB7	5695	pp	--	int.I2D: BioGrid_Yeast
PSMD7	5713	VIM	7431	pp	--	int.I2D: HPRD; int.HPRD: yeast 2-hybrid
PSMB2	5690	PSMB3	5691	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, INTEROLOG, MINT, Yu_GoldStd, BCI, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid
ACTB	60	RPA2	6118	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
KPNB1	3837	PSMA1	5682	pp	--	int.I2D: YeastLow
PSMB3	5691	POLE4	56655	pd	<	reg.ITFP.txt: no annot
PSMA2	5683	PSMD7	5713	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMA1	5682	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMB2	5690	PSMD11	5717	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMB2	5690	VARS	7407	pd	<	reg.ITFP.txt: no annot
PSMD7	5713	PSMD11	5717	pp	--	int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastHigh, BioGrid, IntAct
PSMB3	5691	PSMD7	5713	pp	--	int.I2D: YeastLow
PSMB3	5691	PSMD11	5717	pp	--	int.I2D: YeastLow
KPNB1	3837	PSMD11	5717	pp	--	int.I2D: Krogan_NonCore
PSMA2	5683	PSMB2	5690	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core

Related GO terms (266)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0016032	viral process	2.46e-15	4.02e-11	4.503	12	55	540
GO:0006521	regulation of cellular amino acid metabolic process	1.83e-14	2.99e-10	7.158	7	21	50
GO:0000502	proteasome complex	5.49e-14	8.96e-10	6.944	7	22	58
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.27e-13	2.07e-09	6.779	7	24	65
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	1.27e-13	2.07e-09	6.779	7	22	65
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.18e-13	3.55e-09	6.673	7	24	70
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	2.95e-13	4.82e-09	6.612	7	23	73
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.26e-13	5.32e-09	6.592	7	24	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	4.35e-13	7.10e-09	6.535	7	23	77
GO:0000082	G1/S transition of mitotic cell cycle	5.10e-13	8.33e-09	5.766	8	33	150
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	5.24e-13	8.55e-09	6.498	7	25	79
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.84e-12	3.00e-08	6.247	7	23	94
GO:0005839	proteasome core complex	3.85e-12	6.29e-08	8.146	5	11	18
GO:0004298	threonine-type endopeptidase activity	6.96e-12	1.14e-07	7.994	5	11	20
GO:0000209	protein polyubiquitination	8.28e-12	1.35e-07	5.944	7	21	116
GO:0016071	mRNA metabolic process	1.26e-11	2.05e-07	5.194	8	34	223
GO:0006915	apoptotic process	1.68e-11	2.75e-07	4.159	10	34	571
GO:0016070	RNA metabolic process	2.85e-11	4.65e-07	5.046	8	34	247
GO:0042981	regulation of apoptotic process	5.38e-11	8.79e-07	5.563	7	26	151
GO:0034641	cellular nitrogen compound metabolic process	1.65e-10	2.69e-06	5.334	7	25	177
GO:0005654	nucleoplasm	3.77e-10	6.16e-06	3.357	11	83	1095
GO:0005829	cytosol	4.69e-10	7.65e-06	2.479	14	125	2562
GO:0000278	mitotic cell cycle	1.27e-09	2.06e-05	4.358	8	52	398
GO:0010467	gene expression	2.74e-09	4.47e-05	3.779	9	58	669
GO:0043066	negative regulation of apoptotic process	8.20e-08	1.34e-03	4.044	7	30	433
GO:0070062	extracellular vesicular exosome	2.35e-06	3.84e-02	2.157	11	98	2516
GO:0005515	protein binding	4.26e-06	6.95e-02	1.320	15	172	6127
GO:0044281	small molecule metabolic process	1.11e-05	1.81e-01	2.656	8	57	1295
GO:0006921	cellular component disassembly involved in execution phase of apoptosis	1.22e-05	1.99e-01	6.025	3	5	47
GO:0019773	proteasome core complex, alpha-subunit complex	2.51e-05	4.10e-01	7.994	2	5	8
GO:0005838	proteasome regulatory particle	5.91e-05	9.65e-01	7.409	2	7	12
GO:0005634	nucleus	2.28e-04	1.00e+00	1.342	12	131	4828
GO:0097110	scaffold protein binding	4.96e-04	1.00e+00	5.907	2	2	34
GO:0005730	nucleolus	6.06e-04	1.00e+00	2.084	7	70	1684
GO:0031625	ubiquitin protein ligase binding	6.65e-04	1.00e+00	4.088	3	13	180
GO:0070243	regulation of thymocyte apoptotic process	9.80e-04	1.00e+00	9.994	1	1	1
GO:0030690	Noc1p-Noc2p complex	9.80e-04	1.00e+00	9.994	1	1	1
GO:0004832	valine-tRNA ligase activity	1.96e-03	1.00e+00	8.994	1	1	2
GO:0006407	rRNA export from nucleus	1.96e-03	1.00e+00	8.994	1	1	2
GO:0006438	valyl-tRNA aminoacylation	1.96e-03	1.00e+00	8.994	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.96e-03	1.00e+00	8.994	1	1	2
GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway	1.96e-03	1.00e+00	8.994	1	1	2
GO:0005055	laminin receptor activity	1.96e-03	1.00e+00	8.994	1	1	2
GO:0036462	TRAIL-activated apoptotic signaling pathway	2.94e-03	1.00e+00	8.409	1	1	3
GO:0060715	syncytiotrophoblast cell differentiation involved in labyrinthine layer development	2.94e-03	1.00e+00	8.409	1	1	3
GO:0005856	cytoskeleton	3.19e-03	1.00e+00	3.299	3	8	311
GO:0006928	cellular component movement	3.58e-03	1.00e+00	4.471	2	7	92
GO:0005200	structural constituent of cytoskeleton	3.66e-03	1.00e+00	4.455	2	7	93
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.92e-03	1.00e+00	7.994	1	1	4
GO:0030686	90S preribosome	3.92e-03	1.00e+00	7.994	1	1	4
GO:0019788	NEDD8 ligase activity	3.92e-03	1.00e+00	7.994	1	1	4
GO:0060020	Bergmann glial cell differentiation	3.92e-03	1.00e+00	7.994	1	1	4
GO:0035877	death effector domain binding	3.92e-03	1.00e+00	7.994	1	1	4
GO:0031467	Cul7-RING ubiquitin ligase complex	3.92e-03	1.00e+00	7.994	1	1	4
GO:0006610	ribosomal protein import into nucleus	3.92e-03	1.00e+00	7.994	1	1	4
GO:0071782	endoplasmic reticulum tubular network	3.92e-03	1.00e+00	7.994	1	1	4
GO:0016020	membrane	4.61e-03	1.00e+00	1.810	6	80	1746
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	4.89e-03	1.00e+00	7.673	1	2	5
GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process	4.89e-03	1.00e+00	7.673	1	1	5
GO:2000001	regulation of DNA damage checkpoint	4.89e-03	1.00e+00	7.673	1	1	5
GO:0008622	epsilon DNA polymerase complex	4.89e-03	1.00e+00	7.673	1	1	5
GO:0031461	cullin-RING ubiquitin ligase complex	4.89e-03	1.00e+00	7.673	1	1	5
GO:0043248	proteasome assembly	4.89e-03	1.00e+00	7.673	1	1	5
GO:0030891	VCB complex	4.89e-03	1.00e+00	7.673	1	2	5
GO:0000730	DNA recombinase assembly	4.89e-03	1.00e+00	7.673	1	3	5
GO:0032025	response to cobalt ion	4.89e-03	1.00e+00	7.673	1	1	5
GO:0019058	viral life cycle	5.54e-03	1.00e+00	4.149	2	10	115
GO:0031466	Cul5-RING ubiquitin ligase complex	5.87e-03	1.00e+00	7.409	1	1	6
GO:0031265	CD95 death-inducing signaling complex	5.87e-03	1.00e+00	7.409	1	1	6
GO:0030957	Tat protein binding	5.87e-03	1.00e+00	7.409	1	4	6
GO:0031264	death-inducing signaling complex	5.87e-03	1.00e+00	7.409	1	1	6
GO:0060546	negative regulation of necroptotic process	6.84e-03	1.00e+00	7.187	1	1	7
GO:0000028	ribosomal small subunit assembly	6.84e-03	1.00e+00	7.187	1	1	7
GO:0002161	aminoacyl-tRNA editing activity	6.84e-03	1.00e+00	7.187	1	2	7
GO:0031462	Cul2-RING ubiquitin ligase complex	6.84e-03	1.00e+00	7.187	1	2	7
GO:0097342	ripoptosome	6.84e-03	1.00e+00	7.187	1	1	7
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	7.82e-03	1.00e+00	6.994	1	2	8
GO:0097202	activation of cysteine-type endopeptidase activity	7.82e-03	1.00e+00	6.994	1	1	8
GO:0070688	MLL5-L complex	7.82e-03	1.00e+00	6.994	1	1	8
GO:0045116	protein neddylation	7.82e-03	1.00e+00	6.994	1	2	8
GO:0008139	nuclear localization sequence binding	8.79e-03	1.00e+00	6.825	1	2	9
GO:0097284	hepatocyte apoptotic process	8.79e-03	1.00e+00	6.825	1	2	9
GO:0006450	regulation of translational fidelity	9.76e-03	1.00e+00	6.673	1	2	10
GO:0070307	lens fiber cell development	9.76e-03	1.00e+00	6.673	1	2	10
GO:0043005	neuron projection	1.06e-02	1.00e+00	3.664	2	4	161
GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand	1.07e-02	1.00e+00	6.535	1	1	11
GO:0045109	intermediate filament organization	1.07e-02	1.00e+00	6.535	1	1	11
GO:0010569	regulation of double-strand break repair via homologous recombination	1.07e-02	1.00e+00	6.535	1	1	11
GO:0031571	mitotic G1 DNA damage checkpoint	1.07e-02	1.00e+00	6.535	1	3	11
GO:0045651	positive regulation of macrophage differentiation	1.07e-02	1.00e+00	6.535	1	2	11
GO:0014002	astrocyte development	1.07e-02	1.00e+00	6.535	1	1	11
GO:0001841	neural tube formation	1.07e-02	1.00e+00	6.535	1	1	11
GO:0005662	DNA replication factor A complex	1.27e-02	1.00e+00	6.294	1	3	13
GO:0035267	NuA4 histone acetyltransferase complex	1.36e-02	1.00e+00	6.187	1	4	14
GO:0006607	NLS-bearing protein import into nucleus	1.36e-02	1.00e+00	6.187	1	2	14
GO:0032403	protein complex binding	1.38e-02	1.00e+00	3.463	2	7	185
GO:0030225	macrophage differentiation	1.46e-02	1.00e+00	6.088	1	1	15
GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex	1.46e-02	1.00e+00	6.088	1	1	15
GO:0005123	death receptor binding	1.46e-02	1.00e+00	6.088	1	1	15
GO:0030101	natural killer cell activation	1.56e-02	1.00e+00	5.994	1	1	16
GO:0051603	proteolysis involved in cellular protein catabolic process	1.56e-02	1.00e+00	5.994	1	2	16
GO:0050998	nitric-oxide synthase binding	1.56e-02	1.00e+00	5.994	1	1	16
GO:0005212	structural constituent of eye lens	1.56e-02	1.00e+00	5.994	1	1	16
GO:0010243	response to organonitrogen compound	1.65e-02	1.00e+00	5.907	1	2	17
GO:0075733	intracellular transport of virus	1.65e-02	1.00e+00	5.907	1	2	17
GO:0006309	apoptotic DNA fragmentation	1.65e-02	1.00e+00	5.907	1	1	17
GO:0022624	proteasome accessory complex	1.65e-02	1.00e+00	5.907	1	9	17
GO:0035861	site of double-strand break	1.75e-02	1.00e+00	5.825	1	1	18
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	1.85e-02	1.00e+00	5.747	1	1	19
GO:0048863	stem cell differentiation	1.85e-02	1.00e+00	5.747	1	1	19
GO:0097194	execution phase of apoptosis	1.94e-02	1.00e+00	5.673	1	1	20
GO:0006298	mismatch repair	1.94e-02	1.00e+00	5.673	1	6	20
GO:0045862	positive regulation of proteolysis	2.04e-02	1.00e+00	5.602	1	1	21
GO:0000718	nucleotide-excision repair, DNA damage removal	2.04e-02	1.00e+00	5.602	1	5	21
GO:0006297	nucleotide-excision repair, DNA gap filling	2.14e-02	1.00e+00	5.535	1	5	22
GO:0032201	telomere maintenance via semi-conservative replication	2.14e-02	1.00e+00	5.535	1	7	22
GO:0030863	cortical cytoskeleton	2.14e-02	1.00e+00	5.535	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	2.14e-02	1.00e+00	5.535	1	4	22
GO:0031463	Cul3-RING ubiquitin ligase complex	2.23e-02	1.00e+00	5.471	1	2	23
GO:0043236	laminin binding	2.23e-02	1.00e+00	5.471	1	1	23
GO:0006513	protein monoubiquitination	2.23e-02	1.00e+00	5.471	1	1	23
GO:0043044	ATP-dependent chromatin remodeling	2.23e-02	1.00e+00	5.471	1	4	23
GO:0000060	protein import into nucleus, translocation	2.33e-02	1.00e+00	5.409	1	4	24
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	2.42e-02	1.00e+00	5.351	1	2	25
GO:0008536	Ran GTPase binding	2.42e-02	1.00e+00	5.351	1	2	25
GO:0005844	polysome	2.42e-02	1.00e+00	5.351	1	4	25
GO:0042113	B cell activation	2.42e-02	1.00e+00	5.351	1	2	25
GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	2.52e-02	1.00e+00	5.294	1	3	26
GO:0000722	telomere maintenance via recombination	2.52e-02	1.00e+00	5.294	1	7	26
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	2.52e-02	1.00e+00	5.294	1	2	26
GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	2.62e-02	1.00e+00	5.240	1	1	27
GO:0006281	DNA repair	2.69e-02	1.00e+00	2.950	2	22	264
GO:0034612	response to tumor necrosis factor	2.71e-02	1.00e+00	5.187	1	2	28
GO:0043022	ribosome binding	2.71e-02	1.00e+00	5.187	1	3	28
GO:0031492	nucleosomal DNA binding	2.71e-02	1.00e+00	5.187	1	4	28
GO:0019894	kinesin binding	2.71e-02	1.00e+00	5.187	1	1	28
GO:0031252	cell leading edge	2.81e-02	1.00e+00	5.136	1	3	29
GO:0019005	SCF ubiquitin ligase complex	2.81e-02	1.00e+00	5.136	1	1	29
GO:0009409	response to cold	2.81e-02	1.00e+00	5.136	1	2	29
GO:0003887	DNA-directed DNA polymerase activity	2.81e-02	1.00e+00	5.136	1	3	29
GO:0071897	DNA biosynthetic process	2.81e-02	1.00e+00	5.136	1	2	29
GO:0006606	protein import into nucleus	2.90e-02	1.00e+00	5.088	1	1	30
GO:0010977	negative regulation of neuron projection development	2.90e-02	1.00e+00	5.088	1	2	30
GO:0005164	tumor necrosis factor receptor binding	2.90e-02	1.00e+00	5.088	1	3	30
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	2.90e-02	1.00e+00	5.088	1	1	30
GO:0046677	response to antibiotic	3.00e-02	1.00e+00	5.040	1	2	31
GO:0006271	DNA strand elongation involved in DNA replication	3.00e-02	1.00e+00	5.040	1	9	31
GO:0019899	enzyme binding	3.16e-02	1.00e+00	2.825	2	11	288
GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	3.28e-02	1.00e+00	4.907	1	2	34
GO:0034332	adherens junction organization	3.47e-02	1.00e+00	4.825	1	1	36
GO:0001895	retina homeostasis	3.47e-02	1.00e+00	4.825	1	1	36
GO:0008234	cysteine-type peptidase activity	3.57e-02	1.00e+00	4.785	1	2	37
GO:0051084	'de novo' posttranslational protein folding	3.57e-02	1.00e+00	4.785	1	4	37
GO:0030049	muscle filament sliding	3.66e-02	1.00e+00	4.747	1	1	38
GO:0097191	extrinsic apoptotic signaling pathway	3.66e-02	1.00e+00	4.747	1	2	38
GO:0070527	platelet aggregation	3.66e-02	1.00e+00	4.747	1	2	38
GO:0006284	base-excision repair	3.76e-02	1.00e+00	4.709	1	7	39
GO:0071407	cellular response to organic cyclic compound	3.76e-02	1.00e+00	4.709	1	2	39
GO:0022627	cytosolic small ribosomal subunit	3.76e-02	1.00e+00	4.709	1	3	39
GO:0000781	chromosome, telomeric region	3.85e-02	1.00e+00	4.673	1	2	40
GO:0006418	tRNA aminoacylation for protein translation	4.04e-02	1.00e+00	4.602	1	5	42
GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	4.14e-02	1.00e+00	4.568	1	2	43
GO:0042110	T cell activation	4.14e-02	1.00e+00	4.568	1	3	43
GO:0014070	response to organic cyclic compound	4.14e-02	1.00e+00	4.568	1	3	43
GO:0043966	histone H3 acetylation	4.32e-02	1.00e+00	4.503	1	2	45
GO:0021762	substantia nigra development	4.42e-02	1.00e+00	4.471	1	1	46
GO:0044297	cell body	4.42e-02	1.00e+00	4.471	1	2	46
GO:0006283	transcription-coupled nucleotide-excision repair	4.42e-02	1.00e+00	4.471	1	8	46
GO:0045111	intermediate filament cytoskeleton	4.70e-02	1.00e+00	4.380	1	1	49
GO:0001948	glycoprotein binding	4.79e-02	1.00e+00	4.351	1	3	50
GO:0003684	damaged DNA binding	4.89e-02	1.00e+00	4.322	1	11	51
GO:0004197	cysteine-type endopeptidase activity	4.98e-02	1.00e+00	4.294	1	2	52
GO:0005925	focal adhesion	4.99e-02	1.00e+00	2.463	2	18	370
GO:0003725	double-stranded RNA binding	5.17e-02	1.00e+00	4.240	1	6	54
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	5.17e-02	1.00e+00	4.240	1	5	54
GO:0008233	peptidase activity	5.26e-02	1.00e+00	4.213	1	3	55
GO:0097193	intrinsic apoptotic signaling pathway	5.26e-02	1.00e+00	4.213	1	4	55
GO:0000932	cytoplasmic mRNA processing body	5.35e-02	1.00e+00	4.187	1	3	56
GO:0008565	protein transporter activity	5.45e-02	1.00e+00	4.162	1	2	57
GO:0051291	protein heterooligomerization	5.45e-02	1.00e+00	4.162	1	1	57
GO:0000724	double-strand break repair via homologous recombination	5.45e-02	1.00e+00	4.162	1	6	57
GO:0045216	cell-cell junction organization	5.63e-02	1.00e+00	4.112	1	2	59
GO:0000723	telomere maintenance	5.63e-02	1.00e+00	4.112	1	8	59
GO:0005643	nuclear pore	5.63e-02	1.00e+00	4.112	1	4	59
GO:0046982	protein heterodimerization activity	5.71e-02	1.00e+00	2.354	2	11	399
GO:0006302	double-strand break repair	5.91e-02	1.00e+00	4.040	1	8	62
GO:0019903	protein phosphatase binding	6.00e-02	1.00e+00	4.017	1	4	63
GO:0005882	intermediate filament	6.28e-02	1.00e+00	3.950	1	1	66
GO:0071260	cellular response to mechanical stimulus	6.28e-02	1.00e+00	3.950	1	4	66
GO:0006289	nucleotide-excision repair	6.56e-02	1.00e+00	3.886	1	12	69
GO:0003697	single-stranded DNA binding	6.56e-02	1.00e+00	3.886	1	9	69
GO:0034329	cell junction assembly	6.74e-02	1.00e+00	3.845	1	1	71
GO:0032355	response to estradiol	6.92e-02	1.00e+00	3.805	1	5	73
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	7.20e-02	1.00e+00	3.747	1	3	76
GO:0035666	TRIF-dependent toll-like receptor signaling pathway	7.20e-02	1.00e+00	3.747	1	2	76
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	7.29e-02	1.00e+00	3.728	1	5	77
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	7.29e-02	1.00e+00	3.728	1	6	77
GO:0002756	MyD88-independent toll-like receptor signaling pathway	7.38e-02	1.00e+00	3.709	1	2	78
GO:0034138	toll-like receptor 3 signaling pathway	7.56e-02	1.00e+00	3.673	1	2	80
GO:0019083	viral transcription	7.66e-02	1.00e+00	3.655	1	8	81
GO:0005739	mitochondrion	7.87e-02	1.00e+00	1.549	3	24	1046
GO:0047485	protein N-terminus binding	8.11e-02	1.00e+00	3.568	1	4	86
GO:0006415	translational termination	8.20e-02	1.00e+00	3.551	1	8	87
GO:0045471	response to ethanol	8.29e-02	1.00e+00	3.535	1	1	88
GO:0044267	cellular protein metabolic process	8.33e-02	1.00e+00	2.043	2	24	495
GO:0005777	peroxisome	8.47e-02	1.00e+00	3.503	1	2	90
GO:0016605	PML body	8.65e-02	1.00e+00	3.471	1	5	92
GO:0006414	translational elongation	8.74e-02	1.00e+00	3.455	1	11	93
GO:0034142	toll-like receptor 4 signaling pathway	9.01e-02	1.00e+00	3.409	1	2	96
GO:0071456	cellular response to hypoxia	9.19e-02	1.00e+00	3.380	1	4	98
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	9.73e-02	1.00e+00	3.294	1	8	104
GO:0014069	postsynaptic density	9.90e-02	1.00e+00	3.267	1	1	106
GO:0005741	mitochondrial outer membrane	1.01e-01	1.00e+00	3.240	1	4	108
GO:0002224	toll-like receptor signaling pathway	1.02e-01	1.00e+00	3.226	1	2	109
GO:0005815	microtubule organizing center	1.03e-01	1.00e+00	3.213	1	4	110
GO:0015630	microtubule cytoskeleton	1.04e-01	1.00e+00	3.187	1	5	112
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.06e-01	1.00e+00	3.162	1	10	114
GO:0030529	ribonucleoprotein complex	1.06e-01	1.00e+00	3.162	1	8	114
GO:0097190	apoptotic signaling pathway	1.08e-01	1.00e+00	3.136	1	4	116
GO:0005635	nuclear envelope	1.08e-01	1.00e+00	3.136	1	6	116
GO:0072562	blood microparticle	1.08e-01	1.00e+00	3.136	1	4	116
GO:0032496	response to lipopolysaccharide	1.13e-01	1.00e+00	3.064	1	4	122
GO:0006325	chromatin organization	1.14e-01	1.00e+00	3.052	1	4	123
GO:0007219	Notch signaling pathway	1.16e-01	1.00e+00	3.029	1	4	125
GO:0006260	DNA replication	1.16e-01	1.00e+00	3.029	1	12	125
GO:0006511	ubiquitin-dependent protein catabolic process	1.18e-01	1.00e+00	3.006	1	5	127
GO:0006413	translational initiation	1.21e-01	1.00e+00	2.961	1	12	131
GO:0045087	innate immune response	1.21e-01	1.00e+00	1.728	2	20	616
GO:0009615	response to virus	1.22e-01	1.00e+00	2.950	1	6	132
GO:0000790	nuclear chromatin	1.23e-01	1.00e+00	2.939	1	7	133
GO:0003735	structural constituent of ribosome	1.30e-01	1.00e+00	2.855	1	8	141
GO:0007507	heart development	1.30e-01	1.00e+00	2.855	1	5	141
GO:0061024	membrane organization	1.34e-01	1.00e+00	2.805	1	5	146
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	1.36e-01	1.00e+00	2.785	1	3	148
GO:0010628	positive regulation of gene expression	1.37e-01	1.00e+00	2.775	1	4	149
GO:0006457	protein folding	1.37e-01	1.00e+00	2.775	1	8	149
GO:0045121	membrane raft	1.47e-01	1.00e+00	2.664	1	8	161
GO:0008022	protein C-terminus binding	1.47e-01	1.00e+00	2.664	1	4	161
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.53e-01	1.00e+00	2.602	1	5	168
GO:0030424	axon	1.56e-01	1.00e+00	2.568	1	3	172
GO:0031965	nuclear membrane	1.59e-01	1.00e+00	2.535	1	4	176
GO:0019904	protein domain specific binding	1.63e-01	1.00e+00	2.495	1	6	181
GO:0015629	actin cytoskeleton	1.65e-01	1.00e+00	2.479	1	5	183
GO:0005737	cytoplasm	1.73e-01	1.00e+00	0.622	6	98	3976
GO:0001525	angiogenesis	1.79e-01	1.00e+00	2.351	1	4	200
GO:0019221	cytokine-mediated signaling pathway	2.03e-01	1.00e+00	2.149	1	3	230
GO:0006412	translation	2.07e-01	1.00e+00	2.118	1	15	235
GO:0004842	ubiquitin-protein transferase activity	2.24e-01	1.00e+00	1.994	1	4	256
GO:0016567	protein ubiquitination	2.56e-01	1.00e+00	1.770	1	5	299
GO:0043234	protein complex	2.57e-01	1.00e+00	1.766	1	17	300
GO:0019901	protein kinase binding	2.72e-01	1.00e+00	1.673	1	21	320
GO:0007411	axon guidance	2.77e-01	1.00e+00	1.641	1	9	327
GO:0008270	zinc ion binding	2.82e-01	1.00e+00	0.935	2	12	1067
GO:0005813	centrosome	2.85e-01	1.00e+00	1.589	1	12	339
GO:0044822	poly(A) RNA binding	2.86e-01	1.00e+00	0.920	2	50	1078
GO:0003723	RNA binding	2.97e-01	1.00e+00	1.523	1	19	355
GO:0043565	sequence-specific DNA binding	3.04e-01	1.00e+00	1.483	1	4	365
GO:0007155	cell adhesion	3.17e-01	1.00e+00	1.409	1	8	384
GO:0006508	proteolysis	3.35e-01	1.00e+00	1.315	1	9	410
GO:0007596	blood coagulation	3.70e-01	1.00e+00	1.136	1	14	464
GO:0042802	identical protein binding	3.87e-01	1.00e+00	1.055	1	18	491
GO:0005524	ATP binding	3.88e-01	1.00e+00	0.591	2	46	1354
GO:0042803	protein homodimerization activity	4.60e-01	1.00e+00	0.725	1	11	617
GO:0005794	Golgi apparatus	4.78e-01	1.00e+00	0.650	1	14	650
GO:0005615	extracellular space	6.40e-01	1.00e+00	0.014	1	17	1010
GO:0005886	plasma membrane	7.94e-01	1.00e+00	-0.474	2	38	2834

Wolf-ratios-Mammosphere-Adherent

meta-int-snw-7431

Interacting subnets

Genes (16)

Interactions (48)

Related GO terms (266)