Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
wolf-screen-ratio-mammosphere-adherent | 0.927 | 3.16e-15 | 2.90e-03 | 4.49e-02 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
RPA2 | 6118 | 98 | 1.250 | 1.151 | 69 | Yes | - |
RBX1 | 9978 | 97 | 1.185 | 1.151 | 139 | Yes | - |
PSMA2 | 5683 | 60 | 1.093 | 1.106 | 89 | Yes | - |
PSMD7 | 5713 | 5 | 0.640 | 0.958 | 133 | Yes | - |
PSMA1 | 5682 | 61 | 0.996 | 1.052 | 123 | Yes | - |
[ VIM ] | 7431 | 1 | 0.044 | 0.927 | 246 | Yes | - |
PSMD11 | 5717 | 121 | 1.095 | 1.106 | 183 | Yes | - |
ACTB | 60 | 167 | 1.153 | 1.151 | 587 | Yes | - |
CASP8 | 841 | 8 | 0.804 | 1.041 | 141 | - | - |
KPNB1 | 3837 | 6 | 0.613 | 1.017 | 296 | Yes | - |
RPSA | 3921 | 156 | 1.327 | 1.151 | 152 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
PSMA2 | 5683 | PSMD7 | 5713 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
CASP8 | 841 | VIM | 7431 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct, BCI, BioGrid, HPRD, MINT, StelzlHigh; int.Mint: MI:0915(physical association); int.HPRD: in vivo |
PSMD7 | 5713 | PSMD11 | 5717 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastHigh, BioGrid, IntAct |
ACTB | 60 | PSMD7 | 5713 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
KPNB1 | 3837 | VIM | 7431 | pp | -- | int.I2D: BIND_Mouse |
RPSA | 3921 | PSMD11 | 5717 | pp | -- | int.I2D: IntAct_Yeast |
ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
KPNB1 | 3837 | PSMA1 | 5682 | pp | -- | int.I2D: YeastLow |
ACTB | 60 | VIM | 7431 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
ACTB | 60 | RPA2 | 6118 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
PSMA2 | 5683 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMD7 | 5713 | VIM | 7431 | pp | -- | int.I2D: HPRD; int.HPRD: yeast 2-hybrid |
PSMA1 | 5682 | PSMD7 | 5713 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium, IntAct_Yeast, MINT_Yeast |
ACTB | 60 | PSMA1 | 5682 | pp | -- | int.I2D: BioGrid_Yeast |
PSMD7 | 5713 | RBX1 | 9978 | pp | -- | int.I2D: YeastLow, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast |
PSMA1 | 5682 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
KPNB1 | 3837 | PSMA2 | 5683 | pp | -- | int.I2D: Krogan_NonCore, YeastLow |
ACTB | 60 | KPNB1 | 3837 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
ACTB | 60 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA1 | 5682 | PSMA2 | 5683 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid |
KPNB1 | 3837 | PSMD11 | 5717 | pp | -- | int.I2D: Krogan_NonCore |
PSMA1 | 5682 | VIM | 7431 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: HPRD, IntAct, BioGrid, MINT, VidalHuman_core; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0016032 | viral process | 6.30e-12 | 9.09e-08 | 4.466 | 9 | 55 | 534 |
GO:0006915 | apoptotic process | 3.47e-08 | 5.01e-04 | 4.048 | 7 | 33 | 555 |
GO:0006521 | regulation of cellular amino acid metabolic process | 4.14e-08 | 5.97e-04 | 6.713 | 4 | 17 | 50 |
GO:0000082 | G1/S transition of mitotic cell cycle | 4.83e-08 | 6.97e-04 | 5.459 | 5 | 32 | 149 |
GO:0000502 | proteasome complex | 7.61e-08 | 1.10e-03 | 6.499 | 4 | 17 | 58 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 1.14e-07 | 1.64e-03 | 6.357 | 4 | 19 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.21e-07 | 1.75e-03 | 6.334 | 4 | 22 | 65 |
GO:0005654 | nucleoplasm | 1.32e-07 | 1.90e-03 | 3.277 | 8 | 76 | 1082 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.64e-07 | 2.36e-03 | 6.227 | 4 | 22 | 70 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 1.83e-07 | 2.65e-03 | 6.187 | 4 | 20 | 72 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 2.05e-07 | 2.96e-03 | 6.147 | 4 | 22 | 74 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 2.16e-07 | 3.12e-03 | 6.128 | 4 | 20 | 75 |
GO:0005829 | cytosol | 2.20e-07 | 3.18e-03 | 2.393 | 10 | 132 | 2496 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 2.67e-07 | 3.85e-03 | 6.053 | 4 | 23 | 79 |
GO:0016071 | mRNA metabolic process | 3.62e-07 | 5.22e-03 | 4.878 | 5 | 31 | 223 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 4.94e-07 | 7.13e-03 | 5.833 | 4 | 21 | 92 |
GO:0016070 | RNA metabolic process | 6.01e-07 | 8.67e-03 | 4.730 | 5 | 32 | 247 |
GO:0000209 | protein polyubiquitination | 1.26e-06 | 1.81e-02 | 5.499 | 4 | 20 | 116 |
GO:0042981 | regulation of apoptotic process | 3.50e-06 | 5.05e-02 | 5.128 | 4 | 24 | 150 |
GO:0006921 | cellular component disassembly involved in execution phase of apoptosis | 5.25e-06 | 7.58e-02 | 6.387 | 3 | 5 | 47 |
GO:0000278 | mitotic cell cycle | 5.76e-06 | 8.31e-02 | 4.068 | 5 | 48 | 391 |
GO:0034641 | cellular nitrogen compound metabolic process | 5.90e-06 | 8.51e-02 | 4.939 | 4 | 20 | 171 |
GO:0019773 | proteasome core complex, alpha-subunit complex | 1.48e-05 | 2.13e-01 | 8.357 | 2 | 4 | 8 |
GO:0005838 | proteasome regulatory particle | 3.48e-05 | 5.01e-01 | 7.772 | 2 | 7 | 12 |
GO:0070062 | extracellular vesicular exosome | 5.96e-05 | 8.59e-01 | 2.128 | 8 | 104 | 2400 |
GO:0005515 | protein binding | 6.71e-05 | 9.68e-01 | 1.260 | 11 | 184 | 6024 |
GO:0010467 | gene expression | 7.74e-05 | 1.00e+00 | 3.293 | 5 | 59 | 669 |
GO:0005839 | proteasome core complex | 8.04e-05 | 1.00e+00 | 7.187 | 2 | 8 | 18 |
GO:0004298 | threonine-type endopeptidase activity | 8.98e-05 | 1.00e+00 | 7.109 | 2 | 8 | 19 |
GO:0043066 | negative regulation of apoptotic process | 2.06e-04 | 1.00e+00 | 3.629 | 4 | 31 | 424 |
GO:0031625 | ubiquitin protein ligase binding | 2.84e-04 | 1.00e+00 | 4.466 | 3 | 14 | 178 |
GO:0097110 | scaffold protein binding | 2.93e-04 | 1.00e+00 | 6.269 | 2 | 3 | 34 |
GO:0030690 | Noc1p-Noc2p complex | 7.63e-04 | 1.00e+00 | 10.357 | 1 | 1 | 1 |
GO:0070243 | regulation of thymocyte apoptotic process | 7.63e-04 | 1.00e+00 | 10.357 | 1 | 1 | 1 |
GO:0005856 | cytoskeleton | 1.19e-03 | 1.00e+00 | 3.757 | 3 | 12 | 291 |
GO:0044281 | small molecule metabolic process | 1.24e-03 | 1.00e+00 | 2.437 | 5 | 58 | 1211 |
GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 1 | 2 |
GO:0097199 | cysteine-type endopeptidase activity involved in apoptotic signaling pathway | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 1 | 2 |
GO:0005055 | laminin receptor activity | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 1 | 2 |
GO:0006407 | rRNA export from nucleus | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 1 | 2 |
GO:0006928 | cellular component movement | 2.09e-03 | 1.00e+00 | 4.849 | 2 | 7 | 91 |
GO:0005200 | structural constituent of cytoskeleton | 2.09e-03 | 1.00e+00 | 4.849 | 2 | 8 | 91 |
GO:0060715 | syncytiotrophoblast cell differentiation involved in labyrinthine layer development | 2.29e-03 | 1.00e+00 | 8.772 | 1 | 1 | 3 |
GO:0036462 | TRAIL-activated apoptotic signaling pathway | 2.29e-03 | 1.00e+00 | 8.772 | 1 | 1 | 3 |
GO:0060020 | Bergmann glial cell differentiation | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:0030686 | 90S preribosome | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:0097153 | cysteine-type endopeptidase activity involved in apoptotic process | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:0035877 | death effector domain binding | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:0031467 | Cul7-RING ubiquitin ligase complex | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:0019788 | NEDD8 ligase activity | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:0006610 | ribosomal protein import into nucleus | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:0071782 | endoplasmic reticulum tubular network | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:0019058 | viral life cycle | 3.31e-03 | 1.00e+00 | 4.511 | 2 | 13 | 115 |
GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex | 3.81e-03 | 1.00e+00 | 8.035 | 1 | 3 | 5 |
GO:0031461 | cullin-RING ubiquitin ligase complex | 3.81e-03 | 1.00e+00 | 8.035 | 1 | 1 | 5 |
GO:0043248 | proteasome assembly | 3.81e-03 | 1.00e+00 | 8.035 | 1 | 1 | 5 |
GO:0030891 | VCB complex | 3.81e-03 | 1.00e+00 | 8.035 | 1 | 2 | 5 |
GO:0000730 | DNA recombinase assembly | 3.81e-03 | 1.00e+00 | 8.035 | 1 | 1 | 5 |
GO:2000001 | regulation of DNA damage checkpoint | 3.81e-03 | 1.00e+00 | 8.035 | 1 | 1 | 5 |
GO:0032025 | response to cobalt ion | 3.81e-03 | 1.00e+00 | 8.035 | 1 | 1 | 5 |
GO:0031265 | CD95 death-inducing signaling complex | 4.57e-03 | 1.00e+00 | 7.772 | 1 | 1 | 6 |
GO:0030957 | Tat protein binding | 4.57e-03 | 1.00e+00 | 7.772 | 1 | 3 | 6 |
GO:0031264 | death-inducing signaling complex | 4.57e-03 | 1.00e+00 | 7.772 | 1 | 1 | 6 |
GO:0031466 | Cul5-RING ubiquitin ligase complex | 4.57e-03 | 1.00e+00 | 7.772 | 1 | 1 | 6 |
GO:0005730 | nucleolus | 4.85e-03 | 1.00e+00 | 1.998 | 5 | 69 | 1641 |
GO:0060546 | negative regulation of necroptotic process | 5.33e-03 | 1.00e+00 | 7.549 | 1 | 1 | 7 |
GO:0097342 | ripoptosome | 5.33e-03 | 1.00e+00 | 7.549 | 1 | 1 | 7 |
GO:0000028 | ribosomal small subunit assembly | 5.33e-03 | 1.00e+00 | 7.549 | 1 | 1 | 7 |
GO:0031462 | Cul2-RING ubiquitin ligase complex | 5.33e-03 | 1.00e+00 | 7.549 | 1 | 2 | 7 |
GO:0016020 | membrane | 5.39e-03 | 1.00e+00 | 1.963 | 5 | 90 | 1681 |
GO:0043005 | neuron projection | 6.07e-03 | 1.00e+00 | 4.062 | 2 | 6 | 157 |
GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex | 6.09e-03 | 1.00e+00 | 7.357 | 1 | 2 | 8 |
GO:0097202 | activation of cysteine-type endopeptidase activity | 6.09e-03 | 1.00e+00 | 7.357 | 1 | 1 | 8 |
GO:0070688 | MLL5-L complex | 6.09e-03 | 1.00e+00 | 7.357 | 1 | 1 | 8 |
GO:0045116 | protein neddylation | 6.09e-03 | 1.00e+00 | 7.357 | 1 | 2 | 8 |
GO:0005634 | nucleus | 6.13e-03 | 1.00e+00 | 1.202 | 8 | 136 | 4559 |
GO:0097284 | hepatocyte apoptotic process | 6.85e-03 | 1.00e+00 | 7.187 | 1 | 3 | 9 |
GO:0008139 | nuclear localization sequence binding | 6.85e-03 | 1.00e+00 | 7.187 | 1 | 3 | 9 |
GO:0070307 | lens fiber cell development | 7.60e-03 | 1.00e+00 | 7.035 | 1 | 2 | 10 |
GO:0001841 | neural tube formation | 7.60e-03 | 1.00e+00 | 7.035 | 1 | 1 | 10 |
GO:0010569 | regulation of double-strand break repair via homologous recombination | 7.60e-03 | 1.00e+00 | 7.035 | 1 | 1 | 10 |
GO:0032403 | protein complex binding | 8.17e-03 | 1.00e+00 | 3.841 | 2 | 10 | 183 |
GO:2001239 | regulation of extrinsic apoptotic signaling pathway in absence of ligand | 8.36e-03 | 1.00e+00 | 6.897 | 1 | 1 | 11 |
GO:0014002 | astrocyte development | 8.36e-03 | 1.00e+00 | 6.897 | 1 | 1 | 11 |
GO:0045109 | intermediate filament organization | 8.36e-03 | 1.00e+00 | 6.897 | 1 | 1 | 11 |
GO:0031571 | mitotic G1 DNA damage checkpoint | 8.36e-03 | 1.00e+00 | 6.897 | 1 | 4 | 11 |
GO:0045651 | positive regulation of macrophage differentiation | 8.36e-03 | 1.00e+00 | 6.897 | 1 | 1 | 11 |
GO:0005662 | DNA replication factor A complex | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 1 | 13 |
GO:0035267 | NuA4 histone acetyltransferase complex | 1.06e-02 | 1.00e+00 | 6.549 | 1 | 4 | 14 |
GO:0006607 | NLS-bearing protein import into nucleus | 1.06e-02 | 1.00e+00 | 6.549 | 1 | 3 | 14 |
GO:0030225 | macrophage differentiation | 1.14e-02 | 1.00e+00 | 6.450 | 1 | 1 | 15 |
GO:0005123 | death receptor binding | 1.14e-02 | 1.00e+00 | 6.450 | 1 | 1 | 15 |
GO:0050998 | nitric-oxide synthase binding | 1.21e-02 | 1.00e+00 | 6.357 | 1 | 1 | 16 |
GO:0030101 | natural killer cell activation | 1.21e-02 | 1.00e+00 | 6.357 | 1 | 1 | 16 |
GO:0005212 | structural constituent of eye lens | 1.21e-02 | 1.00e+00 | 6.357 | 1 | 1 | 16 |
GO:0051603 | proteolysis involved in cellular protein catabolic process | 1.21e-02 | 1.00e+00 | 6.357 | 1 | 2 | 16 |
GO:0075733 | intracellular transport of virus | 1.29e-02 | 1.00e+00 | 6.269 | 1 | 3 | 17 |
GO:0006309 | apoptotic DNA fragmentation | 1.29e-02 | 1.00e+00 | 6.269 | 1 | 1 | 17 |
GO:0022624 | proteasome accessory complex | 1.29e-02 | 1.00e+00 | 6.269 | 1 | 8 | 17 |
GO:0035861 | site of double-strand break | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 1 | 18 |
GO:0097194 | execution phase of apoptosis | 1.44e-02 | 1.00e+00 | 6.109 | 1 | 1 | 19 |
GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.44e-02 | 1.00e+00 | 6.109 | 1 | 1 | 19 |
GO:0048863 | stem cell differentiation | 1.44e-02 | 1.00e+00 | 6.109 | 1 | 1 | 19 |
GO:0006298 | mismatch repair | 1.52e-02 | 1.00e+00 | 6.035 | 1 | 3 | 20 |
GO:0032201 | telomere maintenance via semi-conservative replication | 1.59e-02 | 1.00e+00 | 5.964 | 1 | 5 | 21 |
GO:0045862 | positive regulation of proteolysis | 1.59e-02 | 1.00e+00 | 5.964 | 1 | 1 | 21 |
GO:0000718 | nucleotide-excision repair, DNA damage removal | 1.59e-02 | 1.00e+00 | 5.964 | 1 | 4 | 21 |
GO:0006281 | DNA repair | 1.61e-02 | 1.00e+00 | 3.329 | 2 | 18 | 261 |
GO:0006297 | nucleotide-excision repair, DNA gap filling | 1.67e-02 | 1.00e+00 | 5.897 | 1 | 3 | 22 |
GO:0030863 | cortical cytoskeleton | 1.67e-02 | 1.00e+00 | 5.897 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 1.67e-02 | 1.00e+00 | 5.897 | 1 | 4 | 22 |
GO:0043044 | ATP-dependent chromatin remodeling | 1.74e-02 | 1.00e+00 | 5.833 | 1 | 4 | 23 |
GO:0005844 | polysome | 1.74e-02 | 1.00e+00 | 5.833 | 1 | 4 | 23 |
GO:0031463 | Cul3-RING ubiquitin ligase complex | 1.74e-02 | 1.00e+00 | 5.833 | 1 | 3 | 23 |
GO:0043236 | laminin binding | 1.74e-02 | 1.00e+00 | 5.833 | 1 | 1 | 23 |
GO:0006513 | protein monoubiquitination | 1.74e-02 | 1.00e+00 | 5.833 | 1 | 1 | 23 |
GO:0019899 | enzyme binding | 1.80e-02 | 1.00e+00 | 3.243 | 2 | 12 | 277 |
GO:0000060 | protein import into nucleus, translocation | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 5 | 24 |
GO:0070423 | nucleotide-binding oligomerization domain containing signaling pathway | 1.89e-02 | 1.00e+00 | 5.713 | 1 | 3 | 25 |
GO:0008536 | Ran GTPase binding | 1.89e-02 | 1.00e+00 | 5.713 | 1 | 1 | 25 |
GO:0000722 | telomere maintenance via recombination | 1.89e-02 | 1.00e+00 | 5.713 | 1 | 5 | 25 |
GO:0042113 | B cell activation | 1.89e-02 | 1.00e+00 | 5.713 | 1 | 2 | 25 |
GO:1900740 | positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | 1.97e-02 | 1.00e+00 | 5.656 | 1 | 4 | 26 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 1.97e-02 | 1.00e+00 | 5.656 | 1 | 3 | 26 |
GO:0009409 | response to cold | 1.97e-02 | 1.00e+00 | 5.656 | 1 | 2 | 26 |
GO:0043022 | ribosome binding | 2.04e-02 | 1.00e+00 | 5.602 | 1 | 3 | 27 |
GO:2001238 | positive regulation of extrinsic apoptotic signaling pathway | 2.04e-02 | 1.00e+00 | 5.602 | 1 | 2 | 27 |
GO:0034612 | response to tumor necrosis factor | 2.04e-02 | 1.00e+00 | 5.602 | 1 | 2 | 27 |
GO:0031492 | nucleosomal DNA binding | 2.04e-02 | 1.00e+00 | 5.602 | 1 | 4 | 27 |
GO:0031252 | cell leading edge | 2.12e-02 | 1.00e+00 | 5.549 | 1 | 4 | 28 |
GO:0010977 | negative regulation of neuron projection development | 2.12e-02 | 1.00e+00 | 5.549 | 1 | 2 | 28 |
GO:0019894 | kinesin binding | 2.12e-02 | 1.00e+00 | 5.549 | 1 | 1 | 28 |
GO:0019005 | SCF ubiquitin ligase complex | 2.19e-02 | 1.00e+00 | 5.499 | 1 | 1 | 29 |
GO:0006606 | protein import into nucleus | 2.27e-02 | 1.00e+00 | 5.450 | 1 | 2 | 30 |
GO:0006271 | DNA strand elongation involved in DNA replication | 2.27e-02 | 1.00e+00 | 5.450 | 1 | 7 | 30 |
GO:0005164 | tumor necrosis factor receptor binding | 2.27e-02 | 1.00e+00 | 5.450 | 1 | 2 | 30 |
GO:0043124 | negative regulation of I-kappaB kinase/NF-kappaB signaling | 2.27e-02 | 1.00e+00 | 5.450 | 1 | 1 | 30 |
GO:0046677 | response to antibiotic | 2.34e-02 | 1.00e+00 | 5.402 | 1 | 2 | 31 |
GO:0001895 | retina homeostasis | 2.56e-02 | 1.00e+00 | 5.269 | 1 | 1 | 34 |
GO:0008625 | extrinsic apoptotic signaling pathway via death domain receptors | 2.56e-02 | 1.00e+00 | 5.269 | 1 | 2 | 34 |
GO:0034332 | adherens junction organization | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 1 | 36 |
GO:0008234 | cysteine-type peptidase activity | 2.79e-02 | 1.00e+00 | 5.147 | 1 | 3 | 37 |
GO:0051084 | 'de novo' posttranslational protein folding | 2.79e-02 | 1.00e+00 | 5.147 | 1 | 4 | 37 |
GO:0006284 | base-excision repair | 2.79e-02 | 1.00e+00 | 5.147 | 1 | 3 | 37 |
GO:0030049 | muscle filament sliding | 2.86e-02 | 1.00e+00 | 5.109 | 1 | 1 | 38 |
GO:0097191 | extrinsic apoptotic signaling pathway | 2.86e-02 | 1.00e+00 | 5.109 | 1 | 3 | 38 |
GO:0071407 | cellular response to organic cyclic compound | 2.86e-02 | 1.00e+00 | 5.109 | 1 | 2 | 38 |
GO:0070527 | platelet aggregation | 2.86e-02 | 1.00e+00 | 5.109 | 1 | 2 | 38 |
GO:0022627 | cytosolic small ribosomal subunit | 2.94e-02 | 1.00e+00 | 5.071 | 1 | 4 | 39 |
GO:0000781 | chromosome, telomeric region | 2.94e-02 | 1.00e+00 | 5.071 | 1 | 3 | 39 |
GO:0005925 | focal adhesion | 3.04e-02 | 1.00e+00 | 2.841 | 2 | 19 | 366 |
GO:0042110 | T cell activation | 3.16e-02 | 1.00e+00 | 4.964 | 1 | 3 | 42 |
GO:0035872 | nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway | 3.23e-02 | 1.00e+00 | 4.930 | 1 | 4 | 43 |
GO:0021762 | substantia nigra development | 3.31e-02 | 1.00e+00 | 4.897 | 1 | 2 | 44 |
GO:0006283 | transcription-coupled nucleotide-excision repair | 3.45e-02 | 1.00e+00 | 4.833 | 1 | 7 | 46 |
GO:0044297 | cell body | 3.45e-02 | 1.00e+00 | 4.833 | 1 | 2 | 46 |
GO:0045111 | intermediate filament cytoskeleton | 3.53e-02 | 1.00e+00 | 4.802 | 1 | 1 | 47 |
GO:0003684 | damaged DNA binding | 3.68e-02 | 1.00e+00 | 4.742 | 1 | 7 | 49 |
GO:0004197 | cysteine-type endopeptidase activity | 3.75e-02 | 1.00e+00 | 4.713 | 1 | 3 | 50 |
GO:0001948 | glycoprotein binding | 3.75e-02 | 1.00e+00 | 4.713 | 1 | 3 | 50 |
GO:0003725 | double-stranded RNA binding | 3.90e-02 | 1.00e+00 | 4.656 | 1 | 5 | 52 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 3.97e-02 | 1.00e+00 | 4.629 | 1 | 5 | 53 |
GO:0008233 | peptidase activity | 4.04e-02 | 1.00e+00 | 4.602 | 1 | 2 | 54 |
GO:0045216 | cell-cell junction organization | 4.04e-02 | 1.00e+00 | 4.602 | 1 | 2 | 54 |
GO:0000932 | cytoplasmic mRNA processing body | 4.04e-02 | 1.00e+00 | 4.602 | 1 | 3 | 54 |
GO:0097193 | intrinsic apoptotic signaling pathway | 4.12e-02 | 1.00e+00 | 4.575 | 1 | 6 | 55 |
GO:0000724 | double-strand break repair via homologous recombination | 4.12e-02 | 1.00e+00 | 4.575 | 1 | 3 | 55 |
GO:0008565 | protein transporter activity | 4.19e-02 | 1.00e+00 | 4.549 | 1 | 5 | 56 |
GO:0051291 | protein heterooligomerization | 4.19e-02 | 1.00e+00 | 4.549 | 1 | 2 | 56 |
GO:0000723 | telomere maintenance | 4.19e-02 | 1.00e+00 | 4.549 | 1 | 6 | 56 |
GO:0005643 | nuclear pore | 4.26e-02 | 1.00e+00 | 4.524 | 1 | 4 | 57 |
GO:0005882 | intermediate filament | 4.56e-02 | 1.00e+00 | 4.426 | 1 | 2 | 61 |
GO:0019903 | protein phosphatase binding | 4.63e-02 | 1.00e+00 | 4.402 | 1 | 4 | 62 |
GO:0006302 | double-strand break repair | 4.63e-02 | 1.00e+00 | 4.402 | 1 | 4 | 62 |
GO:0071260 | cellular response to mechanical stimulus | 4.85e-02 | 1.00e+00 | 4.334 | 1 | 5 | 65 |
GO:0044267 | cellular protein metabolic process | 4.87e-02 | 1.00e+00 | 2.468 | 2 | 29 | 474 |
GO:0006289 | nucleotide-excision repair | 5.07e-02 | 1.00e+00 | 4.269 | 1 | 11 | 68 |
GO:0034329 | cell junction assembly | 5.07e-02 | 1.00e+00 | 4.269 | 1 | 1 | 68 |
GO:0003697 | single-stranded DNA binding | 5.07e-02 | 1.00e+00 | 4.269 | 1 | 5 | 68 |
GO:0032355 | response to estradiol | 5.29e-02 | 1.00e+00 | 4.207 | 1 | 5 | 71 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 5.50e-02 | 1.00e+00 | 4.147 | 1 | 6 | 74 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 5.58e-02 | 1.00e+00 | 4.128 | 1 | 2 | 75 |
GO:0035666 | TRIF-dependent toll-like receptor signaling pathway | 5.65e-02 | 1.00e+00 | 4.109 | 1 | 3 | 76 |
GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process | 5.72e-02 | 1.00e+00 | 4.090 | 1 | 7 | 77 |
GO:0002756 | MyD88-independent toll-like receptor signaling pathway | 5.79e-02 | 1.00e+00 | 4.071 | 1 | 3 | 78 |
GO:0034138 | toll-like receptor 3 signaling pathway | 5.86e-02 | 1.00e+00 | 4.053 | 1 | 3 | 79 |
GO:0019083 | viral transcription | 6.01e-02 | 1.00e+00 | 4.017 | 1 | 10 | 81 |
GO:0005777 | peroxisome | 6.23e-02 | 1.00e+00 | 3.964 | 1 | 4 | 84 |
GO:0047485 | protein N-terminus binding | 6.37e-02 | 1.00e+00 | 3.930 | 1 | 5 | 86 |
GO:0045471 | response to ethanol | 6.37e-02 | 1.00e+00 | 3.930 | 1 | 3 | 86 |
GO:0006415 | translational termination | 6.44e-02 | 1.00e+00 | 3.914 | 1 | 10 | 87 |
GO:0016605 | PML body | 6.51e-02 | 1.00e+00 | 3.897 | 1 | 3 | 88 |
GO:0071456 | cellular response to hypoxia | 6.80e-02 | 1.00e+00 | 3.833 | 1 | 6 | 92 |
GO:0006414 | translational elongation | 6.87e-02 | 1.00e+00 | 3.817 | 1 | 13 | 93 |
GO:0034142 | toll-like receptor 4 signaling pathway | 7.09e-02 | 1.00e+00 | 3.772 | 1 | 3 | 96 |
GO:0045087 | innate immune response | 7.32e-02 | 1.00e+00 | 2.137 | 2 | 24 | 596 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 7.65e-02 | 1.00e+00 | 3.656 | 1 | 10 | 104 |
GO:0014069 | postsynaptic density | 7.73e-02 | 1.00e+00 | 3.642 | 1 | 3 | 105 |
GO:0005741 | mitochondrial outer membrane | 7.73e-02 | 1.00e+00 | 3.642 | 1 | 7 | 105 |
GO:0002224 | toll-like receptor signaling pathway | 8.01e-02 | 1.00e+00 | 3.588 | 1 | 3 | 109 |
GO:0005815 | microtubule organizing center | 8.01e-02 | 1.00e+00 | 3.588 | 1 | 5 | 109 |
GO:0072562 | blood microparticle | 8.15e-02 | 1.00e+00 | 3.562 | 1 | 3 | 111 |
GO:0030529 | ribonucleoprotein complex | 8.22e-02 | 1.00e+00 | 3.549 | 1 | 8 | 112 |
GO:0097190 | apoptotic signaling pathway | 8.29e-02 | 1.00e+00 | 3.536 | 1 | 6 | 113 |
GO:0005635 | nuclear envelope | 8.29e-02 | 1.00e+00 | 3.536 | 1 | 6 | 113 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 8.36e-02 | 1.00e+00 | 3.524 | 1 | 11 | 114 |
GO:0006325 | chromatin organization | 8.64e-02 | 1.00e+00 | 3.474 | 1 | 5 | 118 |
GO:0007219 | Notch signaling pathway | 8.78e-02 | 1.00e+00 | 3.450 | 1 | 5 | 120 |
GO:0006260 | DNA replication | 8.85e-02 | 1.00e+00 | 3.438 | 1 | 9 | 121 |
GO:0032496 | response to lipopolysaccharide | 8.85e-02 | 1.00e+00 | 3.438 | 1 | 4 | 121 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 9.20e-02 | 1.00e+00 | 3.379 | 1 | 5 | 126 |
GO:0009615 | response to virus | 9.20e-02 | 1.00e+00 | 3.379 | 1 | 5 | 126 |
GO:0000790 | nuclear chromatin | 9.41e-02 | 1.00e+00 | 3.345 | 1 | 9 | 129 |
GO:0006413 | translational initiation | 9.55e-02 | 1.00e+00 | 3.323 | 1 | 17 | 131 |
GO:0003735 | structural constituent of ribosome | 9.97e-02 | 1.00e+00 | 3.259 | 1 | 10 | 137 |
GO:0007507 | heart development | 1.01e-01 | 1.00e+00 | 3.238 | 1 | 7 | 139 |
GO:0006457 | protein folding | 1.04e-01 | 1.00e+00 | 3.197 | 1 | 7 | 143 |
GO:0061024 | membrane organization | 1.05e-01 | 1.00e+00 | 3.177 | 1 | 7 | 145 |
GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | 1.05e-01 | 1.00e+00 | 3.177 | 1 | 4 | 145 |
GO:0010628 | positive regulation of gene expression | 1.06e-01 | 1.00e+00 | 3.167 | 1 | 5 | 146 |
GO:0045121 | membrane raft | 1.13e-01 | 1.00e+00 | 3.071 | 1 | 8 | 156 |
GO:0008022 | protein C-terminus binding | 1.16e-01 | 1.00e+00 | 3.026 | 1 | 5 | 161 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.19e-01 | 1.00e+00 | 2.990 | 1 | 7 | 165 |
GO:0030424 | axon | 1.20e-01 | 1.00e+00 | 2.982 | 1 | 4 | 166 |
GO:0031965 | nuclear membrane | 1.21e-01 | 1.00e+00 | 2.964 | 1 | 3 | 168 |
GO:0019904 | protein domain specific binding | 1.28e-01 | 1.00e+00 | 2.873 | 1 | 6 | 179 |
GO:0005737 | cytoplasm | 1.33e-01 | 1.00e+00 | 0.799 | 5 | 110 | 3767 |
GO:0001525 | angiogenesis | 1.36e-01 | 1.00e+00 | 2.779 | 1 | 4 | 191 |
GO:0019221 | cytokine-mediated signaling pathway | 1.56e-01 | 1.00e+00 | 2.569 | 1 | 9 | 221 |
GO:0006412 | translation | 1.62e-01 | 1.00e+00 | 2.511 | 1 | 20 | 230 |
GO:0008270 | zinc ion binding | 1.74e-01 | 1.00e+00 | 1.395 | 2 | 12 | 997 |
GO:0004842 | ubiquitin-protein transferase activity | 1.78e-01 | 1.00e+00 | 2.362 | 1 | 6 | 255 |
GO:0044822 | poly(A) RNA binding | 1.90e-01 | 1.00e+00 | 1.312 | 2 | 49 | 1056 |
GO:0043234 | protein complex | 2.03e-01 | 1.00e+00 | 2.152 | 1 | 18 | 295 |
GO:0016567 | protein ubiquitination | 2.03e-01 | 1.00e+00 | 2.152 | 1 | 5 | 295 |
GO:0019901 | protein kinase binding | 2.17e-01 | 1.00e+00 | 2.048 | 1 | 21 | 317 |
GO:0007411 | axon guidance | 2.18e-01 | 1.00e+00 | 2.039 | 1 | 13 | 319 |
GO:0005813 | centrosome | 2.22e-01 | 1.00e+00 | 2.008 | 1 | 14 | 326 |
GO:0003723 | RNA binding | 2.32e-01 | 1.00e+00 | 1.939 | 1 | 20 | 342 |
GO:0007155 | cell adhesion | 2.48e-01 | 1.00e+00 | 1.829 | 1 | 6 | 369 |
GO:0006508 | proteolysis | 2.53e-01 | 1.00e+00 | 1.794 | 1 | 9 | 378 |
GO:0046982 | protein heterodimerization activity | 2.55e-01 | 1.00e+00 | 1.787 | 1 | 13 | 380 |
GO:0007596 | blood coagulation | 2.97e-01 | 1.00e+00 | 1.527 | 1 | 18 | 455 |
GO:0042802 | identical protein binding | 3.13e-01 | 1.00e+00 | 1.438 | 1 | 20 | 484 |
GO:0042803 | protein homodimerization activity | 3.71e-01 | 1.00e+00 | 1.140 | 1 | 12 | 595 |
GO:0005615 | extracellular space | 5.30e-01 | 1.00e+00 | 0.454 | 1 | 17 | 957 |
GO:0005739 | mitochondrion | 5.46e-01 | 1.00e+00 | 0.394 | 1 | 28 | 998 |
GO:0005886 | plasma membrane | 6.12e-01 | 1.00e+00 | 0.022 | 2 | 45 | 2582 |
GO:0005524 | ATP binding | 6.46e-01 | 1.00e+00 | 0.015 | 1 | 60 | 1298 |