int-snw-4137

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.985	1.73e-17	8.02e-04	1.75e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-4137 subnetwork

Genes (14)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
RPA2	6118	98	1.250	1.151	69	Yes	-
CDC16	8881	25	0.950	1.020	80	Yes	-
RBX1	9978	97	1.185	1.151	139	Yes	-
PSMA2	5683	60	1.093	1.106	89	Yes	-
PPP2R1A	5518	9	0.644	0.985	249	Yes	-
PSMD3	5709	57	0.986	1.106	146	Yes	-
PSMB7	5695	48	0.982	1.052	57	Yes	-
PSMA1	5682	61	0.996	1.052	123	Yes	-
PSMD11	5717	121	1.095	1.106	183	Yes	-
ACTB	60	167	1.153	1.151	587	Yes	-
CASP8	841	8	0.804	1.041	141	-	-
[ MAPT ]	4137	1	-0.119	0.985	65	-	-
RPSA	3921	156	1.327	1.151	152	Yes	-
PGD	5226	75	1.201	1.106	138	Yes	-

Interactions (29)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
RPSA	3921	PSMD11	5717	pp	--	int.I2D: IntAct_Yeast
ACTB	60	RPA2	6118	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
PGD	5226	PPP2R1A	5518	pp	--	int.I2D: YeastLow
PSMA2	5683	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMA1	5682	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
PSMA1	5682	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
PSMD3	5709	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
MAPT	4137	PPP2R1A	5518	pp	--	int.I2D: MINT; int.Mint: MI:0208(genetic interaction)
PGD	5226	PSMD3	5709	pp	--	int.I2D: YeastLow
ACTB	60	PSMB7	5695	pp	--	int.I2D: BioGrid_Yeast
PSMA1	5682	PSMA2	5683	pp	--	int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid
PSMA1	5682	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
PPP2R1A	5518	PSMA1	5682	pp	--	int.I2D: IntAct_Mouse
PSMA2	5683	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastLow
ACTB	60	PPP2R1A	5518	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	RBX1	9978	pp	--	int.I2D: BioGrid_Yeast
PPP2R1A	5518	PSMA2	5683	pp	--	int.I2D: IntAct_Mouse
ACTB	60	CDC16	8881	pp	--	int.I2D: YeastLow
ACTB	60	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
PSMB7	5695	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
PPP2R1A	5518	PSMB7	5695	pp	--	int.I2D: IntAct_Mouse
ACTB	60	MAPT	4137	pp	--	int.I2D: BCI; int.HPRD: in vitro
CASP8	841	MAPT	4137	pp	--	int.I2D: BCI; int.HPRD: in vitro, in vivo
PSMB7	5695	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast
PSMA2	5683	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PGD	5226	PSMD11	5717	pp	--	int.I2D: YeastLow
ACTB	60	PSMA1	5682	pp	--	int.I2D: BioGrid_Yeast

Related GO terms (286)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.93e-11	2.79e-07	6.571	6	22	65
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.06e-11	4.41e-07	6.464	6	22	70
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.31e-11	6.22e-07	6.384	6	22	74
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	6.45e-11	9.31e-07	6.290	6	23	79
GO:0016071	mRNA metabolic process	6.02e-10	8.68e-06	5.015	7	31	223
GO:0000278	mitotic cell cycle	7.08e-10	1.02e-05	4.398	8	48	391
GO:0006521	regulation of cellular amino acid metabolic process	7.97e-10	1.15e-05	6.687	5	17	50
GO:0016070	RNA metabolic process	1.23e-09	1.77e-05	4.868	7	32	247
GO:0005829	cytosol	1.43e-09	2.06e-05	2.424	13	132	2496
GO:0000502	proteasome complex	1.72e-09	2.48e-05	6.473	5	17	58
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	2.85e-09	4.11e-05	6.331	5	19	64
GO:0000082	G1/S transition of mitotic cell cycle	3.08e-09	4.45e-05	5.375	6	32	149
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	5.20e-09	7.51e-05	6.161	5	20	72
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	6.41e-09	9.25e-05	6.102	5	20	75
GO:0016032	viral process	8.27e-09	1.19e-04	3.948	8	55	534
GO:0006915	apoptotic process	1.12e-08	1.61e-04	3.892	8	33	555
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.81e-08	2.61e-04	5.807	5	21	92
GO:0000209	protein polyubiquitination	5.83e-08	8.41e-04	5.473	5	20	116
GO:0005654	nucleoplasm	1.03e-07	1.49e-03	3.099	9	76	1082
GO:0042981	regulation of apoptotic process	2.11e-07	3.05e-03	5.102	5	24	150
GO:0034641	cellular nitrogen compound metabolic process	4.06e-07	5.85e-03	4.913	5	20	171
GO:0005839	proteasome core complex	5.89e-07	8.50e-03	7.424	3	8	18
GO:0004298	threonine-type endopeptidase activity	6.99e-07	1.01e-02	7.346	3	8	19
GO:0010467	gene expression	1.16e-06	1.67e-02	3.430	7	59	669
GO:0019773	proteasome core complex, alpha-subunit complex	2.44e-05	3.52e-01	8.009	2	4	8
GO:0043066	negative regulation of apoptotic process	3.45e-05	4.97e-01	3.603	5	31	424
GO:0005838	proteasome regulatory particle	5.74e-05	8.28e-01	7.424	2	7	12
GO:0070062	extracellular vesicular exosome	8.64e-05	1.00e+00	1.950	9	104	2400
GO:0022624	proteasome accessory complex	1.18e-04	1.00e+00	6.921	2	8	17
GO:0036464	cytoplasmic ribonucleoprotein granule	2.00e-04	1.00e+00	6.549	2	4	22
GO:0044281	small molecule metabolic process	5.76e-04	1.00e+00	2.352	6	58	1211
GO:0031625	ubiquitin protein ligase binding	6.09e-04	1.00e+00	4.118	3	14	178
GO:0006921	cellular component disassembly involved in execution phase of apoptosis	9.23e-04	1.00e+00	5.454	2	5	47
GO:0005515	protein binding	9.66e-04	1.00e+00	1.037	12	184	6024
GO:0070243	regulation of thymocyte apoptotic process	9.71e-04	1.00e+00	10.009	1	1	1
GO:0030690	Noc1p-Noc2p complex	9.71e-04	1.00e+00	10.009	1	1	1
GO:0070262	peptidyl-serine dephosphorylation	9.71e-04	1.00e+00	10.009	1	1	1
GO:0019521	D-gluconate metabolic process	9.71e-04	1.00e+00	10.009	1	1	1
GO:0031113	regulation of microtubule polymerization	1.94e-03	1.00e+00	9.009	1	1	2
GO:0006407	rRNA export from nucleus	1.94e-03	1.00e+00	9.009	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.94e-03	1.00e+00	9.009	1	1	2
GO:0019322	pentose biosynthetic process	1.94e-03	1.00e+00	9.009	1	2	2
GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway	1.94e-03	1.00e+00	9.009	1	1	2
GO:0005055	laminin receptor activity	1.94e-03	1.00e+00	9.009	1	1	2
GO:0005634	nucleus	2.58e-03	1.00e+00	1.176	10	136	4559
GO:0060632	regulation of microtubule-based movement	2.91e-03	1.00e+00	8.424	1	1	3
GO:0036462	TRAIL-activated apoptotic signaling pathway	2.91e-03	1.00e+00	8.424	1	1	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	2.91e-03	1.00e+00	8.424	1	1	3
GO:0060715	syncytiotrophoblast cell differentiation involved in labyrinthine layer development	2.91e-03	1.00e+00	8.424	1	1	3
GO:0009051	pentose-phosphate shunt, oxidative branch	2.91e-03	1.00e+00	8.424	1	2	3
GO:0045298	tubulin complex	2.91e-03	1.00e+00	8.424	1	1	3
GO:0005200	structural constituent of cytoskeleton	3.41e-03	1.00e+00	4.501	2	8	91
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.88e-03	1.00e+00	8.009	1	1	4
GO:0030686	90S preribosome	3.88e-03	1.00e+00	8.009	1	1	4
GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process	3.88e-03	1.00e+00	8.009	1	1	4
GO:0019788	NEDD8 ligase activity	3.88e-03	1.00e+00	8.009	1	1	4
GO:0071813	lipoprotein particle binding	3.88e-03	1.00e+00	8.009	1	1	4
GO:0032387	negative regulation of intracellular transport	3.88e-03	1.00e+00	8.009	1	1	4
GO:0035877	death effector domain binding	3.88e-03	1.00e+00	8.009	1	1	4
GO:0031467	Cul7-RING ubiquitin ligase complex	3.88e-03	1.00e+00	8.009	1	1	4
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	4.84e-03	1.00e+00	7.687	1	3	5
GO:0019932	second-messenger-mediated signaling	4.84e-03	1.00e+00	7.687	1	1	5
GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein	4.84e-03	1.00e+00	7.687	1	1	5
GO:2000001	regulation of DNA damage checkpoint	4.84e-03	1.00e+00	7.687	1	1	5
GO:0031461	cullin-RING ubiquitin ligase complex	4.84e-03	1.00e+00	7.687	1	1	5
GO:0043248	proteasome assembly	4.84e-03	1.00e+00	7.687	1	1	5
GO:0030891	VCB complex	4.84e-03	1.00e+00	7.687	1	2	5
GO:0000730	DNA recombinase assembly	4.84e-03	1.00e+00	7.687	1	1	5
GO:0032025	response to cobalt ion	4.84e-03	1.00e+00	7.687	1	1	5
GO:0015630	microtubule cytoskeleton	4.94e-03	1.00e+00	4.227	2	4	110
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	5.30e-03	1.00e+00	4.176	2	11	114
GO:0031466	Cul5-RING ubiquitin ligase complex	5.81e-03	1.00e+00	7.424	1	1	6
GO:0031265	CD95 death-inducing signaling complex	5.81e-03	1.00e+00	7.424	1	1	6
GO:0030957	Tat protein binding	5.81e-03	1.00e+00	7.424	1	3	6
GO:0031264	death-inducing signaling complex	5.81e-03	1.00e+00	7.424	1	1	6
GO:0060546	negative regulation of necroptotic process	6.78e-03	1.00e+00	7.201	1	1	7
GO:0000028	ribosomal small subunit assembly	6.78e-03	1.00e+00	7.201	1	1	7
GO:0031462	Cul2-RING ubiquitin ligase complex	6.78e-03	1.00e+00	7.201	1	2	7
GO:0097342	ripoptosome	6.78e-03	1.00e+00	7.201	1	1	7
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	7.74e-03	1.00e+00	7.009	1	2	8
GO:0097202	activation of cysteine-type endopeptidase activity	7.74e-03	1.00e+00	7.009	1	1	8
GO:0070688	MLL5-L complex	7.74e-03	1.00e+00	7.009	1	1	8
GO:0045116	protein neddylation	7.74e-03	1.00e+00	7.009	1	2	8
GO:0048699	generation of neurons	8.70e-03	1.00e+00	6.839	1	1	9
GO:0008088	axon cargo transport	8.70e-03	1.00e+00	6.839	1	1	9
GO:0097284	hepatocyte apoptotic process	8.70e-03	1.00e+00	6.839	1	3	9
GO:0047497	mitochondrion transport along microtubule	8.70e-03	1.00e+00	6.839	1	3	9
GO:0006098	pentose-phosphate shunt	9.67e-03	1.00e+00	6.687	1	4	10
GO:0010569	regulation of double-strand break repair via homologous recombination	9.67e-03	1.00e+00	6.687	1	1	10
GO:0001841	neural tube formation	9.67e-03	1.00e+00	6.687	1	1	10
GO:0007084	mitotic nuclear envelope reassembly	9.67e-03	1.00e+00	6.687	1	1	10
GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand	1.06e-02	1.00e+00	6.549	1	1	11
GO:0031571	mitotic G1 DNA damage checkpoint	1.06e-02	1.00e+00	6.549	1	4	11
GO:0045651	positive regulation of macrophage differentiation	1.06e-02	1.00e+00	6.549	1	1	11
GO:0031116	positive regulation of microtubule polymerization	1.06e-02	1.00e+00	6.549	1	1	11
GO:0030424	axon	1.09e-02	1.00e+00	3.634	2	4	166
GO:0006275	regulation of DNA replication	1.16e-02	1.00e+00	6.424	1	2	12
GO:0030111	regulation of Wnt signaling pathway	1.16e-02	1.00e+00	6.424	1	1	12
GO:0034399	nuclear periphery	1.16e-02	1.00e+00	6.424	1	1	12
GO:0006672	ceramide metabolic process	1.26e-02	1.00e+00	6.308	1	1	13
GO:0005662	DNA replication factor A complex	1.26e-02	1.00e+00	6.308	1	1	13
GO:0030234	enzyme regulator activity	1.26e-02	1.00e+00	6.308	1	3	13
GO:0032403	protein complex binding	1.32e-02	1.00e+00	3.493	2	10	183
GO:0035267	NuA4 histone acetyltransferase complex	1.35e-02	1.00e+00	6.201	1	4	14
GO:0034185	apolipoprotein binding	1.35e-02	1.00e+00	6.201	1	1	14
GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	1.45e-02	1.00e+00	6.102	1	2	15
GO:0030225	macrophage differentiation	1.45e-02	1.00e+00	6.102	1	1	15
GO:0005123	death receptor binding	1.45e-02	1.00e+00	6.102	1	1	15
GO:0030101	natural killer cell activation	1.54e-02	1.00e+00	6.009	1	1	16
GO:0042176	regulation of protein catabolic process	1.54e-02	1.00e+00	6.009	1	3	16
GO:0051603	proteolysis involved in cellular protein catabolic process	1.54e-02	1.00e+00	6.009	1	2	16
GO:0050998	nitric-oxide synthase binding	1.54e-02	1.00e+00	6.009	1	1	16
GO:0005730	nucleolus	1.57e-02	1.00e+00	1.650	5	69	1641
GO:0035861	site of double-strand break	1.73e-02	1.00e+00	5.839	1	1	18
GO:0016020	membrane	1.73e-02	1.00e+00	1.616	5	90	1681
GO:0007088	regulation of mitosis	1.73e-02	1.00e+00	5.839	1	1	18
GO:0045773	positive regulation of axon extension	1.73e-02	1.00e+00	5.839	1	4	18
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	1.83e-02	1.00e+00	5.761	1	1	19
GO:0048863	stem cell differentiation	1.83e-02	1.00e+00	5.761	1	1	19
GO:0097194	execution phase of apoptosis	1.83e-02	1.00e+00	5.761	1	1	19
GO:0008601	protein phosphatase type 2A regulator activity	1.92e-02	1.00e+00	5.687	1	2	20
GO:0005680	anaphase-promoting complex	1.92e-02	1.00e+00	5.687	1	4	20
GO:0006298	mismatch repair	1.92e-02	1.00e+00	5.687	1	3	20
GO:0000159	protein phosphatase type 2A complex	1.92e-02	1.00e+00	5.687	1	2	20
GO:0048675	axon extension	2.02e-02	1.00e+00	5.616	1	1	21
GO:0045862	positive regulation of proteolysis	2.02e-02	1.00e+00	5.616	1	1	21
GO:0045595	regulation of cell differentiation	2.02e-02	1.00e+00	5.616	1	1	21
GO:0000718	nucleotide-excision repair, DNA damage removal	2.02e-02	1.00e+00	5.616	1	4	21
GO:0032201	telomere maintenance via semi-conservative replication	2.02e-02	1.00e+00	5.616	1	5	21
GO:0003823	antigen binding	2.12e-02	1.00e+00	5.549	1	1	22
GO:0006297	nucleotide-excision repair, DNA gap filling	2.12e-02	1.00e+00	5.549	1	3	22
GO:0030863	cortical cytoskeleton	2.12e-02	1.00e+00	5.549	1	1	22
GO:0010506	regulation of autophagy	2.21e-02	1.00e+00	5.485	1	1	23
GO:0031463	Cul3-RING ubiquitin ligase complex	2.21e-02	1.00e+00	5.485	1	3	23
GO:0043236	laminin binding	2.21e-02	1.00e+00	5.485	1	1	23
GO:0006513	protein monoubiquitination	2.21e-02	1.00e+00	5.485	1	1	23
GO:0043044	ATP-dependent chromatin remodeling	2.21e-02	1.00e+00	5.485	1	4	23
GO:0005844	polysome	2.21e-02	1.00e+00	5.485	1	4	23
GO:0000722	telomere maintenance via recombination	2.40e-02	1.00e+00	5.365	1	5	25
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	2.40e-02	1.00e+00	5.365	1	3	25
GO:0042113	B cell activation	2.40e-02	1.00e+00	5.365	1	2	25
GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	2.50e-02	1.00e+00	5.308	1	4	26
GO:0070979	protein K11-linked ubiquitination	2.50e-02	1.00e+00	5.308	1	6	26
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	2.50e-02	1.00e+00	5.308	1	3	26
GO:0009409	response to cold	2.50e-02	1.00e+00	5.308	1	2	26
GO:0006281	DNA repair	2.57e-02	1.00e+00	2.981	2	18	261
GO:0010033	response to organic substance	2.59e-02	1.00e+00	5.254	1	2	27
GO:0050661	NADP binding	2.59e-02	1.00e+00	5.254	1	2	27
GO:0000188	inactivation of MAPK activity	2.59e-02	1.00e+00	5.254	1	1	27
GO:0034612	response to tumor necrosis factor	2.59e-02	1.00e+00	5.254	1	2	27
GO:0043022	ribosome binding	2.59e-02	1.00e+00	5.254	1	3	27
GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	2.59e-02	1.00e+00	5.254	1	2	27
GO:0031492	nucleosomal DNA binding	2.59e-02	1.00e+00	5.254	1	4	27
GO:0007628	adult walking behavior	2.69e-02	1.00e+00	5.201	1	1	28
GO:0005875	microtubule associated complex	2.69e-02	1.00e+00	5.201	1	2	28
GO:0019894	kinesin binding	2.69e-02	1.00e+00	5.201	1	1	28
GO:0019005	SCF ubiquitin ligase complex	2.78e-02	1.00e+00	5.151	1	1	29
GO:0019899	enzyme binding	2.87e-02	1.00e+00	2.895	2	12	277
GO:0006271	DNA strand elongation involved in DNA replication	2.87e-02	1.00e+00	5.102	1	7	30
GO:0005164	tumor necrosis factor receptor binding	2.87e-02	1.00e+00	5.102	1	2	30
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	2.87e-02	1.00e+00	5.102	1	1	30
GO:0046677	response to antibiotic	2.97e-02	1.00e+00	5.055	1	2	31
GO:0007094	mitotic spindle assembly checkpoint	2.97e-02	1.00e+00	5.055	1	4	31
GO:0005856	cytoskeleton	3.15e-02	1.00e+00	2.824	2	12	291
GO:0097110	scaffold protein binding	3.25e-02	1.00e+00	4.921	1	3	34
GO:0001895	retina homeostasis	3.25e-02	1.00e+00	4.921	1	1	34
GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	3.25e-02	1.00e+00	4.921	1	2	34
GO:0005876	spindle microtubule	3.25e-02	1.00e+00	4.921	1	2	34
GO:0034332	adherens junction organization	3.44e-02	1.00e+00	4.839	1	1	36
GO:0008234	cysteine-type peptidase activity	3.53e-02	1.00e+00	4.799	1	3	37
GO:0051084	'de novo' posttranslational protein folding	3.53e-02	1.00e+00	4.799	1	4	37
GO:0006284	base-excision repair	3.53e-02	1.00e+00	4.799	1	3	37
GO:0097191	extrinsic apoptotic signaling pathway	3.63e-02	1.00e+00	4.761	1	3	38
GO:0071407	cellular response to organic cyclic compound	3.63e-02	1.00e+00	4.761	1	2	38
GO:0070527	platelet aggregation	3.63e-02	1.00e+00	4.761	1	2	38
GO:0019901	protein kinase binding	3.68e-02	1.00e+00	2.700	2	21	317
GO:0000781	chromosome, telomeric region	3.72e-02	1.00e+00	4.723	1	3	39
GO:0005930	axoneme	3.72e-02	1.00e+00	4.723	1	1	39
GO:0022627	cytosolic small ribosomal subunit	3.72e-02	1.00e+00	4.723	1	4	39
GO:0005813	centrosome	3.87e-02	1.00e+00	2.660	2	14	326
GO:0042110	T cell activation	4.00e-02	1.00e+00	4.616	1	3	42
GO:0004722	protein serine/threonine phosphatase activity	4.00e-02	1.00e+00	4.616	1	1	42
GO:0030155	regulation of cell adhesion	4.00e-02	1.00e+00	4.616	1	2	42
GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	4.10e-02	1.00e+00	4.582	1	4	43
GO:0021762	substantia nigra development	4.19e-02	1.00e+00	4.549	1	2	44
GO:0044297	cell body	4.38e-02	1.00e+00	4.485	1	2	46
GO:0006283	transcription-coupled nucleotide-excision repair	4.38e-02	1.00e+00	4.485	1	7	46
GO:0003684	damaged DNA binding	4.65e-02	1.00e+00	4.394	1	7	49
GO:0000775	chromosome, centromeric region	4.75e-02	1.00e+00	4.365	1	2	50
GO:0040008	regulation of growth	4.75e-02	1.00e+00	4.365	1	5	50
GO:0004197	cysteine-type endopeptidase activity	4.75e-02	1.00e+00	4.365	1	3	50
GO:0000226	microtubule cytoskeleton organization	4.93e-02	1.00e+00	4.308	1	3	52
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	5.03e-02	1.00e+00	4.281	1	5	53
GO:0046982	protein heterodimerization activity	5.11e-02	1.00e+00	2.439	2	13	380
GO:0008233	peptidase activity	5.12e-02	1.00e+00	4.254	1	2	54
GO:0045216	cell-cell junction organization	5.12e-02	1.00e+00	4.254	1	2	54
GO:0000932	cytoplasmic mRNA processing body	5.12e-02	1.00e+00	4.254	1	3	54
GO:0097193	intrinsic apoptotic signaling pathway	5.21e-02	1.00e+00	4.227	1	6	55
GO:0000724	double-strand break repair via homologous recombination	5.21e-02	1.00e+00	4.227	1	3	55
GO:0051291	protein heterooligomerization	5.30e-02	1.00e+00	4.201	1	2	56
GO:0000723	telomere maintenance	5.30e-02	1.00e+00	4.201	1	6	56
GO:0007059	chromosome segregation	5.86e-02	1.00e+00	4.055	1	4	62
GO:0006302	double-strand break repair	5.86e-02	1.00e+00	4.055	1	4	62
GO:0019903	protein phosphatase binding	5.86e-02	1.00e+00	4.055	1	4	62
GO:0071260	cellular response to mechanical stimulus	6.13e-02	1.00e+00	3.986	1	5	65
GO:0006289	nucleotide-excision repair	6.40e-02	1.00e+00	3.921	1	11	68
GO:0003697	single-stranded DNA binding	6.40e-02	1.00e+00	3.921	1	5	68
GO:0034329	cell junction assembly	6.40e-02	1.00e+00	3.921	1	1	68
GO:0032355	response to estradiol	6.68e-02	1.00e+00	3.859	1	5	71
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	6.95e-02	1.00e+00	3.799	1	6	74
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	7.04e-02	1.00e+00	3.780	1	2	75
GO:0035666	TRIF-dependent toll-like receptor signaling pathway	7.13e-02	1.00e+00	3.761	1	3	76
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	7.22e-02	1.00e+00	3.742	1	7	77
GO:0002756	MyD88-independent toll-like receptor signaling pathway	7.31e-02	1.00e+00	3.723	1	3	78
GO:0034138	toll-like receptor 3 signaling pathway	7.40e-02	1.00e+00	3.705	1	3	79
GO:0044267	cellular protein metabolic process	7.56e-02	1.00e+00	2.120	2	29	474
GO:0019083	viral transcription	7.59e-02	1.00e+00	3.669	1	10	81
GO:0047485	protein N-terminus binding	8.04e-02	1.00e+00	3.582	1	5	86
GO:0045471	response to ethanol	8.04e-02	1.00e+00	3.582	1	3	86
GO:0006415	translational termination	8.13e-02	1.00e+00	3.566	1	10	87
GO:0016605	PML body	8.21e-02	1.00e+00	3.549	1	3	88
GO:0006928	cellular component movement	8.48e-02	1.00e+00	3.501	1	7	91
GO:0071456	cellular response to hypoxia	8.57e-02	1.00e+00	3.485	1	6	92
GO:0006414	translational elongation	8.66e-02	1.00e+00	3.470	1	13	93
GO:0001764	neuron migration	8.66e-02	1.00e+00	3.470	1	3	93
GO:0030426	growth cone	8.93e-02	1.00e+00	3.424	1	5	96
GO:0034142	toll-like receptor 4 signaling pathway	8.93e-02	1.00e+00	3.424	1	3	96
GO:0006470	protein dephosphorylation	9.11e-02	1.00e+00	3.394	1	1	98
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	9.64e-02	1.00e+00	3.308	1	10	104
GO:0014069	postsynaptic density	9.73e-02	1.00e+00	3.294	1	3	105
GO:0005741	mitochondrial outer membrane	9.73e-02	1.00e+00	3.294	1	7	105
GO:0002224	toll-like receptor signaling pathway	1.01e-01	1.00e+00	3.241	1	3	109
GO:0005815	microtubule organizing center	1.01e-01	1.00e+00	3.241	1	5	109
GO:0030308	negative regulation of cell growth	1.02e-01	1.00e+00	3.227	1	6	110
GO:0030529	ribonucleoprotein complex	1.03e-01	1.00e+00	3.201	1	8	112
GO:0006461	protein complex assembly	1.03e-01	1.00e+00	3.214	1	6	111
GO:0072562	blood microparticle	1.03e-01	1.00e+00	3.214	1	3	111
GO:0005819	spindle	1.03e-01	1.00e+00	3.201	1	7	112
GO:0017124	SH3 domain binding	1.04e-01	1.00e+00	3.189	1	3	113
GO:0097190	apoptotic signaling pathway	1.04e-01	1.00e+00	3.189	1	6	113
GO:0019058	viral life cycle	1.06e-01	1.00e+00	3.163	1	13	115
GO:0006325	chromatin organization	1.09e-01	1.00e+00	3.126	1	5	118
GO:0007219	Notch signaling pathway	1.10e-01	1.00e+00	3.102	1	5	120
GO:0032496	response to lipopolysaccharide	1.11e-01	1.00e+00	3.090	1	4	121
GO:0006260	DNA replication	1.11e-01	1.00e+00	3.090	1	9	121
GO:0045087	innate immune response	1.12e-01	1.00e+00	1.790	2	24	596
GO:0009615	response to virus	1.16e-01	1.00e+00	3.031	1	5	126
GO:0006511	ubiquitin-dependent protein catabolic process	1.16e-01	1.00e+00	3.031	1	5	126
GO:0000790	nuclear chromatin	1.18e-01	1.00e+00	2.998	1	9	129
GO:0006413	translational initiation	1.20e-01	1.00e+00	2.975	1	17	131
GO:0000086	G2/M transition of mitotic cell cycle	1.24e-01	1.00e+00	2.921	1	9	136
GO:0003735	structural constituent of ribosome	1.25e-01	1.00e+00	2.911	1	10	137
GO:0007507	heart development	1.27e-01	1.00e+00	2.890	1	7	139
GO:0006457	protein folding	1.30e-01	1.00e+00	2.849	1	7	143
GO:0061024	membrane organization	1.32e-01	1.00e+00	2.829	1	7	145
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	1.32e-01	1.00e+00	2.829	1	4	145
GO:0008017	microtubule binding	1.34e-01	1.00e+00	2.809	1	6	147
GO:0045121	membrane raft	1.41e-01	1.00e+00	2.723	1	8	156
GO:0008543	fibroblast growth factor receptor signaling pathway	1.41e-01	1.00e+00	2.723	1	9	156
GO:0043005	neuron projection	1.42e-01	1.00e+00	2.714	1	6	157
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.49e-01	1.00e+00	2.642	1	7	165
GO:0001525	angiogenesis	1.70e-01	1.00e+00	2.431	1	4	191
GO:0007067	mitotic nuclear division	1.99e-01	1.00e+00	2.182	1	14	227
GO:0008380	RNA splicing	2.00e-01	1.00e+00	2.176	1	11	228
GO:0006412	translation	2.02e-01	1.00e+00	2.163	1	20	230
GO:0005874	microtubule	2.16e-01	1.00e+00	2.049	1	7	249
GO:0005975	carbohydrate metabolic process	2.20e-01	1.00e+00	2.026	1	9	253
GO:0004842	ubiquitin-protein transferase activity	2.21e-01	1.00e+00	2.014	1	6	255
GO:0016567	protein ubiquitination	2.51e-01	1.00e+00	1.804	1	5	295
GO:0043234	protein complex	2.51e-01	1.00e+00	1.804	1	18	295
GO:0005739	mitochondrion	2.52e-01	1.00e+00	1.046	2	28	998
GO:0007411	axon guidance	2.69e-01	1.00e+00	1.691	1	13	319
GO:0008283	cell proliferation	2.75e-01	1.00e+00	1.651	1	14	328
GO:0003723	RNA binding	2.85e-01	1.00e+00	1.591	1	20	342
GO:0005737	cytoplasm	2.92e-01	1.00e+00	0.451	5	110	3767
GO:0005925	focal adhesion	3.02e-01	1.00e+00	1.493	1	19	366
GO:0007155	cell adhesion	3.04e-01	1.00e+00	1.481	1	6	369
GO:0006508	proteolysis	3.11e-01	1.00e+00	1.446	1	9	378
GO:0055114	oxidation-reduction process	3.39e-01	1.00e+00	1.294	1	12	420
GO:0007596	blood coagulation	3.62e-01	1.00e+00	1.179	1	18	455
GO:0005615	extracellular space	6.18e-01	1.00e+00	0.106	1	17	957
GO:0006355	regulation of transcription, DNA-templated	6.33e-01	1.00e+00	0.047	1	18	997
GO:0008270	zinc ion binding	6.33e-01	1.00e+00	0.047	1	12	997
GO:0044822	poly(A) RNA binding	6.55e-01	1.00e+00	-0.036	1	49	1056
GO:0005524	ATP binding	7.33e-01	1.00e+00	-0.333	1	60	1298
GO:0005886	plasma membrane	7.44e-01	1.00e+00	-0.326	2	45	2582

Wolf-ratios-Mammosphere-Adherent

int-snw-4137

Statistics

Genes (14)

Interactions (29)

Related GO terms (286)