reg-snw-9650

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.380	3.16e-08	1.39e-02	1.17e-02

chia-screen-data-Fav-reg-snw-9650 subnetwork

Genes (15)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
NDUFA4L2	56901	44	-2.477	2.459	21	-	Yes	-
EIF2S2	8894	40	-2.999	2.459	22	-	Yes	Yes
FBXL6	26233	28	-2.253	2.689	22	-	Yes	-
NCBP1	4686	41	-2.510	2.459	44	-	Yes	Yes
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
POLR2E	5434	30	-2.037	2.644	201	TF	Yes	-
FTSJ1	24140	43	-2.463	2.689	35	-	Yes	Yes
VARS	7407	60	-2.366	2.689	124	TF	Yes	-
CENPQ	55166	20	-2.137	2.459	16	-	Yes	-
CCT7	10574	40	-2.335	2.459	38	-	Yes	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
POLH	5429	36	-2.586	2.459	24	-	Yes	Yes
PSPH	5723	14	-2.063	2.387	11	-	Yes	-
FBXO22	26263	36	-1.739	2.459	208	TF	-	-
[ MTFR1 ]	9650	1	-1.375	2.380	13	-	-	-

Interactions (17)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
VARS	7407	FBXO22	26263	pd	<>	reg.ITFP.txt: no annot
VARS	7407	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
PHB	5245	VARS	7407	pd	<	reg.ITFP.txt: no annot
POLR2E	5434	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
POLR2E	5434	VARS	7407	pd	<>	reg.ITFP.txt: no annot
PHB	5245	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
POLH	5429	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
VARS	7407	MTFR1	9650	pd	>	reg.ITFP.txt: no annot
FBXO22	26263	CENPQ	55166	pd	>	reg.ITFP.txt: no annot
NCBP1	4686	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
VARS	7407	FBXL6	26233	pd	>	reg.ITFP.txt: no annot
EIF2S2	8894	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
PSPH	5723	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
FBXO22	26263	NDUFA4L2	56901	pd	>	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
CCT7	10574	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
MTFR1	9650	FBXO22	26263	pd	<	reg.ITFP.txt: no annot

Related GO terms (153)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006370	7-methylguanosine mRNA capping	5.96e-04	1.00e+00	5.762	2	5	24
GO:0050434	positive regulation of viral transcription	1.27e-03	1.00e+00	5.217	2	5	35
GO:0004832	valine-tRNA ligase activity	1.54e-03	1.00e+00	9.347	1	1	1
GO:0002128	tRNA nucleoside ribose methylation	1.54e-03	1.00e+00	9.347	1	1	1
GO:0008175	tRNA methyltransferase activity	1.54e-03	1.00e+00	9.347	1	1	1
GO:0006438	valyl-tRNA aminoacylation	1.54e-03	1.00e+00	9.347	1	1	1
GO:0005739	mitochondrion	2.34e-03	1.00e+00	2.304	5	32	659
GO:0006368	transcription elongation from RNA polymerase II promoter	2.79e-03	1.00e+00	4.646	2	8	52
GO:0048742	regulation of skeletal muscle fiber development	3.07e-03	1.00e+00	8.347	1	1	2
GO:0004647	phosphoserine phosphatase activity	3.07e-03	1.00e+00	8.347	1	1	2
GO:0005846	nuclear cap binding complex	3.07e-03	1.00e+00	8.347	1	1	2
GO:0002176	male germ cell proliferation	3.07e-03	1.00e+00	8.347	1	1	2
GO:0005850	eukaryotic translation initiation factor 2 complex	4.60e-03	1.00e+00	7.762	1	2	3
GO:0006563	L-serine metabolic process	4.60e-03	1.00e+00	7.762	1	1	3
GO:0045292	mRNA cis splicing, via spliceosome	6.13e-03	1.00e+00	7.347	1	1	4
GO:0031442	positive regulation of mRNA 3'-end processing	6.13e-03	1.00e+00	7.347	1	1	4
GO:0006290	pyrimidine dimer repair	6.13e-03	1.00e+00	7.347	1	2	4
GO:0006564	L-serine biosynthetic process	6.13e-03	1.00e+00	7.347	1	1	4
GO:0010467	gene expression	7.49e-03	1.00e+00	2.283	4	49	535
GO:0006282	regulation of DNA repair	7.66e-03	1.00e+00	7.025	1	2	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	7.66e-03	1.00e+00	7.025	1	1	5
GO:0002161	aminoacyl-tRNA editing activity	7.66e-03	1.00e+00	7.025	1	1	5
GO:0005654	nucleoplasm	8.04e-03	1.00e+00	1.894	5	68	876
GO:0050847	progesterone receptor signaling pathway	9.18e-03	1.00e+00	6.762	1	2	6
GO:0002181	cytoplasmic translation	9.18e-03	1.00e+00	6.762	1	1	6
GO:0001055	RNA polymerase II activity	9.18e-03	1.00e+00	6.762	1	3	6
GO:0002199	zona pellucida receptor complex	1.07e-02	1.00e+00	6.539	1	4	7
GO:0000731	DNA synthesis involved in DNA repair	1.07e-02	1.00e+00	6.539	1	1	7
GO:0006301	postreplication repair	1.07e-02	1.00e+00	6.539	1	2	7
GO:0000339	RNA cap binding	1.07e-02	1.00e+00	6.539	1	1	7
GO:0005832	chaperonin-containing T-complex	1.07e-02	1.00e+00	6.539	1	4	7
GO:0005829	cytosol	1.11e-02	1.00e+00	1.351	7	88	1787
GO:0005845	mRNA cap binding complex	1.22e-02	1.00e+00	6.347	1	1	8
GO:0006450	regulation of translational fidelity	1.22e-02	1.00e+00	6.347	1	1	8
GO:0010944	negative regulation of transcription by competitive promoter binding	1.22e-02	1.00e+00	6.347	1	1	8
GO:0010388	cullin deneddylation	1.22e-02	1.00e+00	6.347	1	4	8
GO:0010225	response to UV-C	1.37e-02	1.00e+00	6.177	1	2	9
GO:0006379	mRNA cleavage	1.37e-02	1.00e+00	6.177	1	2	9
GO:0071354	cellular response to interleukin-6	1.37e-02	1.00e+00	6.177	1	1	9
GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.37e-02	1.00e+00	6.177	1	2	9
GO:0005736	DNA-directed RNA polymerase I complex	1.53e-02	1.00e+00	6.025	1	4	10
GO:0005095	GTPase inhibitor activity	1.53e-02	1.00e+00	6.025	1	1	10
GO:0001054	RNA polymerase I activity	1.53e-02	1.00e+00	6.025	1	4	10
GO:0000398	mRNA splicing, via spliceosome	1.60e-02	1.00e+00	3.347	2	15	128
GO:0060766	negative regulation of androgen receptor signaling pathway	1.68e-02	1.00e+00	5.887	1	4	11
GO:0008652	cellular amino acid biosynthetic process	1.68e-02	1.00e+00	5.887	1	2	11
GO:0008334	histone mRNA metabolic process	1.68e-02	1.00e+00	5.887	1	1	11
GO:0000266	mitochondrial fission	1.68e-02	1.00e+00	5.887	1	2	11
GO:0005666	DNA-directed RNA polymerase III complex	1.98e-02	1.00e+00	5.646	1	3	13
GO:0005665	DNA-directed RNA polymerase II, core complex	1.98e-02	1.00e+00	5.646	1	3	13
GO:0001056	RNA polymerase III activity	1.98e-02	1.00e+00	5.646	1	3	13
GO:0006386	termination of RNA polymerase III transcription	2.13e-02	1.00e+00	5.539	1	3	14
GO:0006385	transcription elongation from RNA polymerase III promoter	2.13e-02	1.00e+00	5.539	1	3	14
GO:0016575	histone deacetylation	2.13e-02	1.00e+00	5.539	1	2	14
GO:0008135	translation factor activity, nucleic acid binding	2.28e-02	1.00e+00	5.440	1	4	15
GO:0000188	inactivation of MAPK activity	2.28e-02	1.00e+00	5.440	1	1	15
GO:0007339	binding of sperm to zona pellucida	2.28e-02	1.00e+00	5.440	1	4	15
GO:0003887	DNA-directed DNA polymerase activity	2.43e-02	1.00e+00	5.347	1	2	16
GO:0009060	aerobic respiration	2.43e-02	1.00e+00	5.347	1	1	16
GO:0008380	RNA splicing	2.58e-02	1.00e+00	2.980	2	21	165
GO:0031667	response to nutrient levels	2.58e-02	1.00e+00	5.259	1	2	17
GO:0005737	cytoplasm	2.71e-02	1.00e+00	0.984	8	127	2633
GO:0003899	DNA-directed RNA polymerase activity	2.73e-02	1.00e+00	5.177	1	3	18
GO:0031047	gene silencing by RNA	2.73e-02	1.00e+00	5.177	1	2	18
GO:0033574	response to testosterone	2.73e-02	1.00e+00	5.177	1	1	18
GO:0004842	ubiquitin-protein transferase activity	3.00e-02	1.00e+00	2.863	2	17	179
GO:0006913	nucleocytoplasmic transport	3.03e-02	1.00e+00	5.025	1	2	20
GO:0034080	CENP-A containing nucleosome assembly	3.03e-02	1.00e+00	5.025	1	2	20
GO:0071897	DNA biosynthetic process	3.03e-02	1.00e+00	5.025	1	2	20
GO:0034660	ncRNA metabolic process	3.03e-02	1.00e+00	5.025	1	1	20
GO:0051084	'de novo' posttranslational protein folding	3.33e-02	1.00e+00	4.887	1	4	22
GO:0000387	spliceosomal snRNP assembly	3.33e-02	1.00e+00	4.887	1	1	22
GO:0008180	COP9 signalosome	3.63e-02	1.00e+00	4.762	1	6	24
GO:0006281	DNA repair	3.78e-02	1.00e+00	2.681	2	24	203
GO:0009267	cellular response to starvation	3.92e-02	1.00e+00	4.646	1	1	26
GO:0006360	transcription from RNA polymerase I promoter	4.07e-02	1.00e+00	4.592	1	4	27
GO:0007005	mitochondrion organization	4.22e-02	1.00e+00	4.539	1	2	28
GO:0006418	tRNA aminoacylation for protein translation	4.37e-02	1.00e+00	4.489	1	4	29
GO:0006383	transcription from RNA polymerase III promoter	4.37e-02	1.00e+00	4.489	1	6	29
GO:0006446	regulation of translational initiation	4.37e-02	1.00e+00	4.489	1	2	29
GO:0045111	intermediate filament cytoskeleton	4.66e-02	1.00e+00	4.392	1	3	31
GO:0007254	JNK cascade	5.10e-02	1.00e+00	4.259	1	1	34
GO:0031124	mRNA 3'-end processing	5.25e-02	1.00e+00	4.217	1	4	35
GO:0044297	cell body	5.25e-02	1.00e+00	4.217	1	5	35
GO:0003723	RNA binding	5.39e-02	1.00e+00	2.398	2	22	247
GO:0003743	translation initiation factor activity	5.54e-02	1.00e+00	4.137	1	8	37
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	5.68e-02	1.00e+00	4.099	1	4	38
GO:0006369	termination of RNA polymerase II transcription	5.68e-02	1.00e+00	4.099	1	5	38
GO:0006283	transcription-coupled nucleotide-excision repair	5.98e-02	1.00e+00	4.025	1	6	40
GO:0000775	chromosome, centromeric region	6.12e-02	1.00e+00	3.989	1	6	41
GO:0003684	damaged DNA binding	6.12e-02	1.00e+00	3.989	1	1	41
GO:0006406	mRNA export from nucleus	6.55e-02	1.00e+00	3.887	1	7	44
GO:0009612	response to mechanical stimulus	6.84e-02	1.00e+00	3.823	1	2	46
GO:0032481	positive regulation of type I interferon production	7.13e-02	1.00e+00	3.762	1	3	48
GO:0006334	nucleosome assembly	7.56e-02	1.00e+00	3.674	1	4	51
GO:0006289	nucleotide-excision repair	7.84e-02	1.00e+00	3.619	1	6	53
GO:0016311	dephosphorylation	8.13e-02	1.00e+00	3.565	1	3	55
GO:0008584	male gonad development	8.41e-02	1.00e+00	3.514	1	1	57
GO:0042826	histone deacetylase binding	8.55e-02	1.00e+00	3.489	1	5	58
GO:0006464	cellular protein modification process	8.98e-02	1.00e+00	3.416	1	4	61
GO:0030018	Z disc	9.40e-02	1.00e+00	3.347	1	3	64
GO:0006366	transcription from RNA polymerase II promoter	9.47e-02	1.00e+00	1.933	2	23	341
GO:0044267	cellular protein metabolic process	9.99e-02	1.00e+00	1.887	2	14	352
GO:0030308	negative regulation of cell growth	1.02e-01	1.00e+00	3.217	1	3	70
GO:0051082	unfolded protein binding	1.02e-01	1.00e+00	3.217	1	5	70
GO:0001649	osteoblast differentiation	1.08e-01	1.00e+00	3.137	1	5	74
GO:0030529	ribonucleoprotein complex	1.19e-01	1.00e+00	2.989	1	5	82
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.22e-01	1.00e+00	2.954	1	5	84
GO:0000209	protein polyubiquitination	1.32e-01	1.00e+00	2.823	1	6	92
GO:0006511	ubiquitin-dependent protein catabolic process	1.32e-01	1.00e+00	2.823	1	6	92
GO:0006260	DNA replication	1.35e-01	1.00e+00	2.792	1	9	94
GO:0016032	viral process	1.38e-01	1.00e+00	1.605	2	30	428
GO:0006457	protein folding	1.39e-01	1.00e+00	2.747	1	5	97
GO:0006413	translational initiation	1.42e-01	1.00e+00	2.717	1	6	99
GO:0034641	cellular nitrogen compound metabolic process	1.50e-01	1.00e+00	2.632	1	5	105
GO:0042981	regulation of apoptotic process	1.59e-01	1.00e+00	2.539	1	4	112
GO:0043005	neuron projection	1.60e-01	1.00e+00	2.526	1	6	113
GO:0000287	magnesium ion binding	1.63e-01	1.00e+00	2.501	1	4	115
GO:0007049	cell cycle	1.63e-01	1.00e+00	2.501	1	8	115
GO:0044212	transcription regulatory region DNA binding	1.99e-01	1.00e+00	2.187	1	13	143
GO:0001701	in utero embryonic development	2.12e-01	1.00e+00	2.080	1	7	154
GO:0006367	transcription initiation from RNA polymerase II promoter	2.21e-01	1.00e+00	2.016	1	18	161
GO:0005874	microtubule	2.23e-01	1.00e+00	1.998	1	10	163
GO:0016071	mRNA metabolic process	2.32e-01	1.00e+00	1.937	1	10	170
GO:0006412	translation	2.41e-01	1.00e+00	1.871	1	12	178
GO:0016567	protein ubiquitination	2.53e-01	1.00e+00	1.792	1	14	188
GO:0016070	RNA metabolic process	2.53e-01	1.00e+00	1.792	1	10	188
GO:0005743	mitochondrial inner membrane	2.64e-01	1.00e+00	1.724	1	9	197
GO:0019899	enzyme binding	2.78e-01	1.00e+00	1.632	1	7	210
GO:0006508	proteolysis	3.37e-01	1.00e+00	1.302	1	11	264
GO:0008285	negative regulation of cell proliferation	3.51e-01	1.00e+00	1.233	1	11	277
GO:0044822	poly(A) RNA binding	3.51e-01	1.00e+00	0.704	2	45	799
GO:0005634	nucleus	3.79e-01	1.00e+00	0.267	6	158	3246
GO:0000278	mitotic cell cycle	3.88e-01	1.00e+00	1.052	1	28	314
GO:0045892	negative regulation of transcription, DNA-templated	3.91e-01	1.00e+00	1.038	1	17	317
GO:0005524	ATP binding	4.04e-01	1.00e+00	0.546	2	37	892
GO:0005509	calcium ion binding	4.23e-01	1.00e+00	0.891	1	9	351
GO:0042802	identical protein binding	4.26e-01	1.00e+00	0.879	1	15	354
GO:0046872	metal ion binding	4.28e-01	1.00e+00	0.479	2	24	934
GO:0045893	positive regulation of transcription, DNA-templated	4.46e-01	1.00e+00	0.788	1	21	377
GO:0005515	protein binding	4.60e-01	1.00e+00	0.144	7	198	4124
GO:0042803	protein homodimerization activity	4.90e-01	1.00e+00	0.605	1	13	428
GO:0045087	innate immune response	5.09e-01	1.00e+00	0.526	1	12	452
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	5.12e-01	1.00e+00	0.514	1	29	456
GO:0005730	nucleolus	5.74e-01	1.00e+00	0.097	2	74	1217
GO:0005887	integral component of plasma membrane	5.98e-01	1.00e+00	0.179	1	8	575
GO:0007165	signal transduction	6.25e-01	1.00e+00	0.075	1	24	618
GO:0006355	regulation of transcription, DNA-templated	6.81e-01	1.00e+00	-0.135	1	31	715
GO:0044281	small molecule metabolic process	7.43e-01	1.00e+00	-0.375	1	35	844
GO:0070062	extracellular vesicular exosome	7.45e-01	1.00e+00	-0.334	2	51	1641
GO:0003677	DNA binding	7.84e-01	1.00e+00	-0.541	1	52	947
GO:0005886	plasma membrane	7.89e-01	1.00e+00	-0.454	2	46	1784
GO:0016020	membrane	8.62e-01	1.00e+00	-0.891	1	56	1207

chia-Fav

reg-snw-9650

Statistics

Genes (15)

Interactions (17)

Related GO terms (153)