reg-snw-7543

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.200 2.86e-07 4.67e-02 3.54e-02
chia-screen-data-Fav-reg-snw-7543 subnetwork

Genes (20)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
NDUFA4L2 56901 44-2.4772.45921-Yes-
DCP1B 196513 1-1.9892.2005---
PHB 5245 82-2.7432.68936-YesYes
MED28 80306 8-2.4042.4456-Yes-
KIAA1551 55196 6-1.8522.36935---
CBLL1 79872 9-1.8972.44538TF--
VARS 7407 60-2.3662.689124TFYes-
UBR5 51366 1-2.0062.20010-Yes-
FBXO22 26263 36-1.7392.459208TF--
FOXJ3 22887 15-2.4072.36987TFYesYes
[ ZFX ] 7543 1-0.8672.2005TF--
TPR 7175 10-2.6382.44536TFYesYes
NCBP1 4686 41-2.5102.45944-YesYes
EIF2S2 8894 40-2.9992.45922-YesYes
PIAS2 9063 2-1.1362.30822TF--
OGT 8473 1-1.0222.20012TF--
CCT7 10574 40-2.3352.45938-Yes-
GPS1 2873 86-3.6212.68936TFYesYes
POLH 5429 36-2.5862.45924-YesYes
FUBP1 8880 5-2.4142.38918TFYesYes

Interactions (21)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
FOXJ3 22887 KIAA1551 55196 pd > reg.ITFP.txt: no annot
VARS 7407 FBXO22 26263 pd <> reg.ITFP.txt: no annot
PHB 5245 VARS 7407 pd < reg.ITFP.txt: no annot
PIAS2 9063 KIAA1551 55196 pd > reg.ITFP.txt: no annot
CBLL1 79872 MED28 80306 pd > reg.ITFP.txt: no annot
PHB 5245 FBXO22 26263 pd < reg.ITFP.txt: no annot
POLH 5429 FBXO22 26263 pd < reg.ITFP.txt: no annot
OGT 8473 DCP1B 196513 pd > reg.ITFP.txt: no annot
ZFX 7543 OGT 8473 pd <> reg.ITFP.txt: no annot
NCBP1 4686 FBXO22 26263 pd < reg.ITFP.txt: no annot
ZFX 7543 PIAS2 9063 pd <> reg.ITFP.txt: no annot
NCBP1 4686 TPR 7175 pd < reg.ITFP.txt: no annot
OGT 8473 UBR5 51366 pd > reg.ITFP.txt: no annot
EIF2S2 8894 FBXO22 26263 pd < reg.ITFP.txt: no annot
FBXO22 26263 KIAA1551 55196 pd > reg.ITFP.txt: no annot
NCBP1 4686 CBLL1 79872 pd < reg.ITFP.txt: no annot
FBXO22 26263 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
FUBP1 8880 UBR5 51366 pd > reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot
CCT7 10574 FBXO22 26263 pd < reg.ITFP.txt: no annot
NCBP1 4686 ZFX 7543 pd < reg.ITFP.txt: no annot

Related GO terms (242)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0050847progesterone receptor signaling pathway5.95e-055.81e-017.347226
GO:0060766negative regulation of androgen receptor signaling pathway2.17e-041.00e+006.4722411
GO:0004832valine-tRNA ligase activity2.05e-031.00e+008.931111
GO:1901673regulation of spindle assembly involved in mitosis2.05e-031.00e+008.931111
GO:0043578nuclear matrix organization2.05e-031.00e+008.931111
GO:0010965regulation of mitotic sister chromatid separation2.05e-031.00e+008.931111
GO:0006404RNA import into nucleus2.05e-031.00e+008.931111
GO:0031453positive regulation of heterochromatin assembly2.05e-031.00e+008.931111
GO:0006438valyl-tRNA aminoacylation2.05e-031.00e+008.931111
GO:0097363protein O-GlcNAc transferase activity2.05e-031.00e+008.931111
GO:0016262protein N-acetylglucosaminyltransferase activity2.05e-031.00e+008.931111
GO:0046626regulation of insulin receptor signaling pathway2.05e-031.00e+008.931111
GO:0000189MAPK import into nucleus4.09e-031.00e+007.931112
GO:0048742regulation of skeletal muscle fiber development4.09e-031.00e+007.931112
GO:0031990mRNA export from nucleus in response to heat stress4.09e-031.00e+007.931112
GO:0090526regulation of gluconeogenesis involved in cellular glucose homeostasis4.09e-031.00e+007.931112
GO:0042306regulation of protein import into nucleus4.09e-031.00e+007.931112
GO:0005846nuclear cap binding complex4.09e-031.00e+007.931112
GO:0002176male germ cell proliferation4.09e-031.00e+007.931112
GO:0070840dynein complex binding4.09e-031.00e+007.931112
GO:0046832negative regulation of RNA export from nucleus4.09e-031.00e+007.931112
GO:0004842ubiquitin-protein transferase activity5.49e-031.00e+003.033317179
GO:0005850eukaryotic translation initiation factor 2 complex6.13e-031.00e+007.347123
GO:0043995histone acetyltransferase activity (H4-K5 specific)6.13e-031.00e+007.347113
GO:0046972histone acetyltransferase activity (H4-K16 specific)6.13e-031.00e+007.347113
GO:1901315negative regulation of histone H2A K63-linked ubiquitination6.13e-031.00e+007.347123
GO:0006405RNA export from nucleus6.13e-031.00e+007.347113
GO:0010793regulation of mRNA export from nucleus6.13e-031.00e+007.347113
GO:0043996histone acetyltransferase activity (H4-K8 specific)6.13e-031.00e+007.347113
GO:0051151negative regulation of smooth muscle cell differentiation8.17e-031.00e+006.931114
GO:0045292mRNA cis splicing, via spliceosome8.17e-031.00e+006.931114
GO:0031442positive regulation of mRNA 3'-end processing8.17e-031.00e+006.931114
GO:0006290pyrimidine dimer repair8.17e-031.00e+006.931124
GO:0006999nuclear pore organization8.17e-031.00e+006.931114
GO:0006110regulation of glycolytic process8.17e-031.00e+006.931114
GO:0061087positive regulation of histone H3-K27 methylation8.17e-031.00e+006.931114
GO:0070849response to epidermal growth factor8.17e-031.00e+006.931114
GO:0044615nuclear pore nuclear basket8.17e-031.00e+006.931114
GO:0005739mitochondrion9.13e-031.00e+001.889532659
GO:0046825regulation of protein export from nucleus1.02e-021.00e+006.610115
GO:2000780negative regulation of double-strand break repair1.02e-021.00e+006.610125
GO:0035020regulation of Rac protein signal transduction1.02e-021.00e+006.610115
GO:0043495protein anchor1.02e-021.00e+006.610115
GO:0006282regulation of DNA repair1.02e-021.00e+006.610125
GO:2000323negative regulation of glucocorticoid receptor signaling pathway1.02e-021.00e+006.610115
GO:0002161aminoacyl-tRNA editing activity1.02e-021.00e+006.610115
GO:0005515protein binding1.13e-021.00e+000.729141984124
GO:0090267positive regulation of mitotic cell cycle spindle assembly checkpoint1.22e-021.00e+006.347116
GO:0030854positive regulation of granulocyte differentiation1.22e-021.00e+006.347116
GO:0070688MLL5-L complex1.22e-021.00e+006.347116
GO:0080182histone H3-K4 trimethylation1.22e-021.00e+006.347116
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.26e-021.00e+003.5392584
GO:0005634nucleus1.26e-021.00e+000.852121583246
GO:0003723RNA binding1.33e-021.00e+002.568322247
GO:0002199zona pellucida receptor complex1.43e-021.00e+006.124147
GO:0043981histone H4-K5 acetylation1.43e-021.00e+006.124117
GO:0000731DNA synthesis involved in DNA repair1.43e-021.00e+006.124117
GO:0006301postreplication repair1.43e-021.00e+006.124127
GO:0043982histone H4-K8 acetylation1.43e-021.00e+006.124117
GO:0000339RNA cap binding1.43e-021.00e+006.124117
GO:0005832chaperonin-containing T-complex1.43e-021.00e+006.124147
GO:0005868cytoplasmic dynein complex1.43e-021.00e+006.124117
GO:0034450ubiquitin-ubiquitin ligase activity1.43e-021.00e+006.124117
GO:0000209protein polyubiquitination1.49e-021.00e+003.4082692
GO:0006511ubiquitin-dependent protein catabolic process1.49e-021.00e+003.4082692
GO:0035413positive regulation of catenin import into nucleus1.63e-021.00e+005.931118
GO:0005845mRNA cap binding complex1.63e-021.00e+005.931118
GO:0045667regulation of osteoblast differentiation1.63e-021.00e+005.931128
GO:0042405nuclear inclusion body1.63e-021.00e+005.931118
GO:0008375acetylglucosaminyltransferase activity1.63e-021.00e+005.931118
GO:0051292nuclear pore complex assembly1.63e-021.00e+005.931148
GO:0006450regulation of translational fidelity1.63e-021.00e+005.931118
GO:0043984histone H4-K16 acetylation1.63e-021.00e+005.931118
GO:0000123histone acetyltransferase complex1.63e-021.00e+005.931118
GO:0010944negative regulation of transcription by competitive promoter binding1.63e-021.00e+005.931118
GO:0010388cullin deneddylation1.63e-021.00e+005.931148
GO:0006493protein O-linked glycosylation1.63e-021.00e+005.931118
GO:0035457cellular response to interferon-alpha1.63e-021.00e+005.931118
GO:0010225response to UV-C1.83e-021.00e+005.762129
GO:0019789SUMO ligase activity1.83e-021.00e+005.762119
GO:0006379mRNA cleavage1.83e-021.00e+005.762129
GO:0045947negative regulation of translational initiation1.83e-021.00e+005.762119
GO:0071354cellular response to interleukin-61.83e-021.00e+005.762119
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process1.83e-021.00e+005.762129
GO:0051571positive regulation of histone H3-K4 methylation2.03e-021.00e+005.6101110
GO:0005095GTPase inhibitor activity2.03e-021.00e+005.6101110
GO:0033160positive regulation of protein import into nucleus, translocation2.03e-021.00e+005.6101110
GO:0010467gene expression2.14e-021.00e+001.868449535
GO:0051019mitogen-activated protein kinase binding2.23e-021.00e+005.4721111
GO:0008334histone mRNA metabolic process2.23e-021.00e+005.4721111
GO:0090316positive regulation of intracellular protein transport2.23e-021.00e+005.4721111
GO:0045807positive regulation of endocytosis2.23e-021.00e+005.4721111
GO:0005487nucleocytoplasmic transporter activity2.23e-021.00e+005.4721211
GO:0046827positive regulation of protein export from nucleus2.23e-021.00e+005.4721111
GO:0042307positive regulation of protein import into nucleus2.43e-021.00e+005.3471312
GO:0034399nuclear periphery2.43e-021.00e+005.3471312
GO:0016575histone deacetylation2.83e-021.00e+005.1241214
GO:0005654nucleoplasm2.85e-021.00e+001.479568876
GO:0008135translation factor activity, nucleic acid binding3.03e-021.00e+005.0251415
GO:0000188inactivation of MAPK activity3.03e-021.00e+005.0251115
GO:0007339binding of sperm to zona pellucida3.03e-021.00e+005.0251415
GO:0030864cortical actin cytoskeleton3.23e-021.00e+004.9311116
GO:0003887DNA-directed DNA polymerase activity3.23e-021.00e+004.9311216
GO:0045862positive regulation of proteolysis3.43e-021.00e+004.8441317
GO:0016874ligase activity3.54e-021.00e+002.742211146
GO:0006611protein export from nucleus3.63e-021.00e+004.7621118
GO:0031047gene silencing by RNA3.63e-021.00e+004.7621218
GO:0031397negative regulation of protein ubiquitination3.63e-021.00e+004.7621218
GO:0001205RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription3.82e-021.00e+004.6841119
GO:0015631tubulin binding4.02e-021.00e+004.6101120
GO:0006913nucleocytoplasmic transport4.02e-021.00e+004.6101220
GO:0072686mitotic spindle4.02e-021.00e+004.6101220
GO:0071897DNA biosynthetic process4.02e-021.00e+004.6101220
GO:0034660ncRNA metabolic process4.02e-021.00e+004.6101120
GO:0005547phosphatidylinositol-3,4,5-trisphosphate binding4.22e-021.00e+004.5391121
GO:0031647regulation of protein stability4.22e-021.00e+004.5391221
GO:0006606protein import into nucleus4.41e-021.00e+004.4721322
GO:0043928exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay4.41e-021.00e+004.4721322
GO:0016925protein sumoylation4.41e-021.00e+004.4721322
GO:0051084'de novo' posttranslational protein folding4.41e-021.00e+004.4721422
GO:0000387spliceosomal snRNP assembly4.41e-021.00e+004.4721122
GO:0034605cellular response to heat4.41e-021.00e+004.4721122
GO:0016071mRNA metabolic process4.66e-021.00e+002.522210170
GO:0007162negative regulation of cell adhesion4.81e-021.00e+004.3471224
GO:00063707-methylguanosine mRNA capping4.81e-021.00e+004.3471524
GO:0008180COP9 signalosome4.81e-021.00e+004.3471624
GO:0016592mediator complex5.00e-021.00e+004.2881625
GO:0010827regulation of glucose transport5.00e-021.00e+004.2881725
GO:0007094mitotic spindle assembly checkpoint5.00e-021.00e+004.2881425
GO:0009267cellular response to starvation5.20e-021.00e+004.2311126
GO:0003713transcription coactivator activity5.37e-021.00e+002.408221184
GO:0008047enzyme activator activity5.39e-021.00e+004.1771227
GO:0006355regulation of transcription, DNA-templated5.39e-021.00e+001.450431715
GO:0016070RNA metabolic process5.58e-021.00e+002.377210188
GO:0031072heat shock protein binding5.59e-021.00e+004.1241128
GO:0006418tRNA aminoacylation for protein translation5.78e-021.00e+004.0731429
GO:0006446regulation of translational initiation5.78e-021.00e+004.0731229
GO:0043130ubiquitin binding5.97e-021.00e+004.0251330
GO:0019898extrinsic component of membrane5.97e-021.00e+004.0251130
GO:0050681androgen receptor binding5.97e-021.00e+004.0251230
GO:0007077mitotic nuclear envelope disassembly6.36e-021.00e+003.9311932
GO:0071300cellular response to retinoic acid6.36e-021.00e+003.9311132
GO:0006281DNA repair6.39e-021.00e+002.266224203
GO:0007254JNK cascade6.74e-021.00e+003.8441134
GO:0050434positive regulation of viral transcription6.94e-021.00e+003.8021535
GO:0030521androgen receptor signaling pathway6.94e-021.00e+003.8021335
GO:0031124mRNA 3'-end processing6.94e-021.00e+003.8021435
GO:0044297cell body6.94e-021.00e+003.8021535
GO:0090263positive regulation of canonical Wnt signaling pathway7.13e-021.00e+003.7621236
GO:0008645hexose transport7.13e-021.00e+003.7621836
GO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic process7.32e-021.00e+003.7221237
GO:0003743translation initiation factor activity7.32e-021.00e+003.7221837
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process7.51e-021.00e+003.6841438
GO:0006369termination of RNA polymerase II transcription7.51e-021.00e+003.6841538
GO:0044822poly(A) RNA binding7.53e-021.00e+001.289445799
GO:0032868response to insulin7.70e-021.00e+003.6461139
GO:0019827stem cell maintenance7.70e-021.00e+003.6461439
GO:0000288nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay7.89e-021.00e+003.6101440
GO:0016787hydrolase activity7.89e-021.00e+003.6101340
GO:0032922circadian regulation of gene expression8.08e-021.00e+003.5741241
GO:0003684damaged DNA binding8.08e-021.00e+003.5741141
GO:0007584response to nutrient8.64e-021.00e+003.4721144
GO:0006406mRNA export from nucleus8.64e-021.00e+003.4721744
GO:0043085positive regulation of catalytic activity8.83e-021.00e+003.4401245
GO:0015758glucose transport9.39e-021.00e+003.3471848
GO:0000151ubiquitin ligase complex9.39e-021.00e+003.3471448
GO:0005643nuclear pore9.95e-021.00e+003.25911251
GO:0006368transcription elongation from RNA polymerase II promoter1.01e-011.00e+003.2311852
GO:0000776kinetochore1.07e-011.00e+003.1501855
GO:0008584male gonad development1.11e-011.00e+003.0991157
GO:0003729mRNA binding1.11e-011.00e+003.0991457
GO:0003697single-stranded DNA binding1.11e-011.00e+003.0991457
GO:0042826histone deacetylase binding1.12e-011.00e+003.0731558
GO:0006464cellular protein modification process1.18e-011.00e+003.0011461
GO:0016337single organismal cell-cell adhesion1.20e-011.00e+002.9771362
GO:0030018Z disc1.23e-011.00e+002.9311364
GO:0030308negative regulation of cell growth1.34e-011.00e+002.8021370
GO:0006325chromatin organization1.34e-011.00e+002.8021470
GO:0051082unfolded protein binding1.34e-011.00e+002.8021570
GO:0001649osteoblast differentiation1.41e-011.00e+002.7221574
GO:0045944positive regulation of transcription from RNA polymerase II promoter1.41e-011.00e+001.186329644
GO:0005737cytoplasm1.44e-011.00e+000.56981272633
GO:0005829cytosol1.44e-011.00e+000.7136881787
GO:0005815microtubule organizing center1.47e-011.00e+002.6651477
GO:0016605PML body1.50e-011.00e+002.6281579
GO:0006366transcription from RNA polymerase II promoter1.53e-011.00e+001.518223341
GO:0030529ribonucleoprotein complex1.55e-011.00e+002.5741582
GO:0005215transporter activity1.55e-011.00e+002.5741582
GO:0048015phosphatidylinositol-mediated signaling1.57e-011.00e+002.5561283
GO:0005635nuclear envelope1.57e-011.00e+002.5561683
GO:0044267cellular protein metabolic process1.61e-011.00e+001.472214352
GO:0042802identical protein binding1.63e-011.00e+001.464215354
GO:0006351transcription, DNA-templated1.72e-011.00e+000.8604471076
GO:0006260DNA replication1.76e-011.00e+002.3771994
GO:0045893positive regulation of transcription, DNA-templated1.79e-011.00e+001.373221377
GO:0006457protein folding1.81e-011.00e+002.3321597
GO:0008270zinc ion binding1.83e-011.00e+001.011339727
GO:0006413translational initiation1.85e-011.00e+002.3021699
GO:0030335positive regulation of cell migration1.88e-011.00e+002.27312101
GO:0010628positive regulation of gene expression1.96e-011.00e+002.20412106
GO:0042981regulation of apoptotic process2.06e-011.00e+002.12414112
GO:0007049cell cycle2.11e-011.00e+002.08618115
GO:0016032viral process2.18e-011.00e+001.190230428
GO:0006974cellular response to DNA damage stimulus2.21e-011.00e+002.013111121
GO:0016607nuclear speck2.23e-011.00e+002.00118122
GO:0016020membrane2.28e-011.00e+000.6944561207
GO:0000398mRNA splicing, via spliceosome2.32e-011.00e+001.931115128
GO:0005730nucleolus2.33e-011.00e+000.6824741217
GO:0031965nuclear membrane2.35e-011.00e+001.90918130
GO:0000122negative regulation of transcription from RNA polymerase II promoter2.39e-011.00e+001.099229456
GO:0031625ubiquitin protein ligase binding2.48e-011.00e+001.82317138
GO:0044212transcription regulatory region DNA binding2.56e-011.00e+001.772113143
GO:0001701in utero embryonic development2.73e-011.00e+001.66517154
GO:0005874microtubule2.86e-011.00e+001.583110163
GO:0008380RNA splicing2.89e-011.00e+001.565121165
GO:0007067mitotic nuclear division2.89e-011.00e+001.56519165
GO:0046872metal ion binding2.98e-011.00e+000.649324934
GO:0019221cytokine-mediated signaling pathway2.99e-011.00e+001.505110172
GO:0006412translation3.08e-011.00e+001.456112178
GO:0003779actin binding3.10e-011.00e+001.44813179
GO:0005975carbohydrate metabolic process3.20e-011.00e+001.392110186
GO:0016567protein ubiquitination3.22e-011.00e+001.377114188
GO:0005743mitochondrial inner membrane3.35e-011.00e+001.30919197
GO:0003700sequence-specific DNA binding transcription factor activity3.37e-011.00e+000.747222582
GO:0019899enzyme binding3.53e-011.00e+001.21717210
GO:0007165signal transduction3.64e-011.00e+000.660224618
GO:0043231intracellular membrane-bounded organelle3.64e-011.00e+001.16318218
GO:0008283cell proliferation3.91e-011.00e+001.03118239
GO:0003682chromatin binding4.08e-011.00e+000.954115252
GO:0043565sequence-specific DNA binding4.36e-011.00e+000.82818275
GO:0008285negative regulation of cell proliferation4.38e-011.00e+000.818111277
GO:0000278mitotic cell cycle4.80e-011.00e+000.637128314
GO:0045892negative regulation of transcription, DNA-templated4.84e-011.00e+000.623117317
GO:0055085transmembrane transport4.96e-011.00e+000.570113329
GO:0005524ATP binding5.57e-011.00e+000.131237892
GO:0006915apoptotic process5.77e-011.00e+000.248115411
GO:0003677DNA binding5.91e-011.00e+000.044252947
GO:0042803protein homodimerization activity5.92e-011.00e+000.190113428
GO:0005887integral component of plasma membrane7.03e-011.00e+00-0.23618575
GO:0044281small molecule metabolic process8.36e-011.00e+00-0.790135844
GO:0070062extracellular vesicular exosome8.73e-011.00e+00-0.7492511641
GO:0005886plasma membrane9.03e-011.00e+00-0.8692461784