reg-snw-6790

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.315 7.17e-08 2.22e-02 1.77e-02
chia-screen-data-Fav-reg-snw-6790 subnetwork

Genes (19)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
NDUFA4L2 56901 44-2.4772.45921-Yes-
CENPA 1058 27-2.1852.393205TFYes-
FOXM1 2305 9-1.6692.412210TF--
PHB 5245 82-2.7432.68936-YesYes
VARS 7407 60-2.3662.689124TFYes-
FBXO22 26263 36-1.7392.459208TF--
EZH2 2146 5-1.6312.315116TF--
EIF2S2 8894 40-2.9992.45922-YesYes
FBXL6 26233 28-2.2532.68922-Yes-
NCBP1 4686 41-2.5102.45944-YesYes
SUV39H2 79723 27-2.3072.41021-YesYes
SHFM1 7979 7-2.3662.3893-Yes-
TRAIP 10293 13-2.5462.45430TFYes-
[ AURKA ] 6790 1-1.4572.31552---
CENPQ 55166 20-2.1372.45916-Yes-
CCT7 10574 40-2.3352.45938-Yes-
GPS1 2873 86-3.6212.68936TFYesYes
POLH 5429 36-2.5862.45924-YesYes
PSPH 5723 14-2.0632.38711-Yes-

Interactions (24)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
VARS 7407 FBXO22 26263 pd <> reg.ITFP.txt: no annot
CENPA 1058 FBXL6 26233 pd > reg.ITFP.txt: no annot
PHB 5245 VARS 7407 pd < reg.ITFP.txt: no annot
FOXM1 2305 AURKA 6790 pd > reg.ITFP.txt: no annot
FOXM1 2305 SHFM1 7979 pd > reg.ITFP.txt: no annot
CENPA 1058 FOXM1 2305 pd <> reg.ITFP.txt: no annot
PHB 5245 FBXO22 26263 pd < reg.ITFP.txt: no annot
AURKA 6790 FBXO22 26263 pd < reg.ITFP.txt: no annot
CENPA 1058 SUV39H2 79723 pd > reg.ITFP.txt: no annot
VARS 7407 FBXL6 26233 pd > reg.ITFP.txt: no annot
EZH2 2146 AURKA 6790 pd > reg.ITFP.txt: no annot
CENPA 1058 AURKA 6790 pd > reg.ITFP.txt: no annot
FBXO22 26263 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot
CCT7 10574 FBXO22 26263 pd < reg.ITFP.txt: no annot
POLH 5429 FBXO22 26263 pd < reg.ITFP.txt: no annot
FBXO22 26263 CENPQ 55166 pd > reg.ITFP.txt: no annot
NCBP1 4686 FBXO22 26263 pd < reg.ITFP.txt: no annot
CENPA 1058 EZH2 2146 pd <> reg.ITFP.txt: no annot
FOXM1 2305 TRAIP 10293 pd <> reg.ITFP.txt: no annot
EIF2S2 8894 FBXO22 26263 pd < reg.ITFP.txt: no annot
PSPH 5723 FBXO22 26263 pd < reg.ITFP.txt: no annot
FOXM1 2305 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
CENPA 1058 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot

Related GO terms (243)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0000775chromosome, centromeric region6.35e-056.20e-015.2333641
GO:0045120pronucleus1.95e-041.00e+006.5462311
GO:0034080CENP-A containing nucleosome assembly6.67e-041.00e+005.6842220
GO:0005654nucleoplasm8.77e-041.00e+002.038768876
GO:0014013regulation of gliogenesis1.95e-031.00e+009.005111
GO:0004832valine-tRNA ligase activity1.95e-031.00e+009.005111
GO:0045605negative regulation of epidermal cell differentiation1.95e-031.00e+009.005111
GO:0046605regulation of centrosome cycle1.95e-031.00e+009.005111
GO:0000939condensed chromosome inner kinetochore1.95e-031.00e+009.005111
GO:0006438valyl-tRNA aminoacylation1.95e-031.00e+009.005111
GO:0090233negative regulation of spindle checkpoint1.95e-031.00e+009.005111
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process2.42e-031.00e+004.7582438
GO:0048511rhythmic process2.42e-031.00e+004.7582538
GO:0000278mitotic cell cycle2.77e-031.00e+002.711428314
GO:0045892negative regulation of transcription, DNA-templated2.87e-031.00e+002.697417317
GO:0048742regulation of skeletal muscle fiber development3.89e-031.00e+008.005112
GO:1900195positive regulation of oocyte maturation3.89e-031.00e+008.005112
GO:0043146spindle stabilization3.89e-031.00e+008.005112
GO:0007057spindle assembly involved in female meiosis I3.89e-031.00e+008.005112
GO:0004647phosphoserine phosphatase activity3.89e-031.00e+008.005112
GO:0005846nuclear cap binding complex3.89e-031.00e+008.005112
GO:0002176male germ cell proliferation3.89e-031.00e+008.005112
GO:0072687meiotic spindle3.89e-031.00e+008.005112
GO:2000781positive regulation of double-strand break repair3.89e-031.00e+008.005112
GO:0007100mitotic centrosome separation3.89e-031.00e+008.005122
GO:0006334nucleosome assembly4.32e-031.00e+004.3332451
GO:0004842ubiquitin-protein transferase activity4.73e-031.00e+003.107317179
GO:0005850eukaryotic translation initiation factor 2 complex5.83e-031.00e+007.421123
GO:0051154negative regulation of striated muscle cell differentiation5.83e-031.00e+007.421113
GO:0036123histone H3-K9 dimethylation5.83e-031.00e+007.421113
GO:0000778condensed nuclear chromosome kinetochore5.83e-031.00e+007.421123
GO:0035404histone-serine phosphorylation5.83e-031.00e+007.421113
GO:0070314G1 to G0 transition5.83e-031.00e+007.421113
GO:0042585germinal vesicle5.83e-031.00e+007.421123
GO:0006563L-serine metabolic process5.83e-031.00e+007.421113
GO:0071459protein localization to chromosome, centromeric region5.83e-031.00e+007.421113
GO:0046976histone methyltransferase activity (H3-K27 specific)7.76e-031.00e+007.005114
GO:0071539protein localization to centrosome7.76e-031.00e+007.005114
GO:0045292mRNA cis splicing, via spliceosome7.76e-031.00e+007.005114
GO:1990138neuron projection extension7.76e-031.00e+007.005114
GO:0031442positive regulation of mRNA 3'-end processing7.76e-031.00e+007.005114
GO:0006290pyrimidine dimer repair7.76e-031.00e+007.005124
GO:0036124histone H3-K9 trimethylation7.76e-031.00e+007.005124
GO:0006333chromatin assembly or disassembly7.76e-031.00e+007.005114
GO:0006564L-serine biosynthetic process7.76e-031.00e+007.005114
GO:0070734histone H3-K27 methylation7.76e-031.00e+007.005114
GO:0071156regulation of cell cycle arrest7.76e-031.00e+007.005124
GO:0035174histone serine kinase activity7.76e-031.00e+007.005114
GO:0090344negative regulation of cell aging9.69e-031.00e+006.684115
GO:0021695cerebellar cortex development9.69e-031.00e+006.684115
GO:0071168protein localization to chromatin9.69e-031.00e+006.684125
GO:0006282regulation of DNA repair9.69e-031.00e+006.684125
GO:0032873negative regulation of stress-activated MAPK cascade9.69e-031.00e+006.684115
GO:2000323negative regulation of glucocorticoid receptor signaling pathway9.69e-031.00e+006.684115
GO:0002161aminoacyl-tRNA editing activity9.69e-031.00e+006.684115
GO:0043203axon hillock9.69e-031.00e+006.684115
GO:0031616spindle pole centrosome9.69e-031.00e+006.684115
GO:0000122negative regulation of transcription from RNA polymerase II promoter1.04e-021.00e+002.173429456
GO:0042127regulation of cell proliferation1.04e-021.00e+003.6842480
GO:0003723RNA binding1.15e-021.00e+002.642322247
GO:0050847progesterone receptor signaling pathway1.16e-021.00e+006.421126
GO:0042754negative regulation of circadian rhythm1.16e-021.00e+006.421126
GO:0046974histone methyltransferase activity (H3-K9 specific)1.16e-021.00e+006.421116
GO:0046578regulation of Ras protein signal transduction1.16e-021.00e+006.421116
GO:0003682chromatin binding1.21e-021.00e+002.613315252
GO:0034244negative regulation of transcription elongation from RNA polymerase II promoter1.35e-021.00e+006.198117
GO:0002199zona pellucida receptor complex1.35e-021.00e+006.198147
GO:0042054histone methyltransferase activity1.35e-021.00e+006.198117
GO:0007140male meiosis1.35e-021.00e+006.198117
GO:0000731DNA synthesis involved in DNA repair1.35e-021.00e+006.198117
GO:0006301postreplication repair1.35e-021.00e+006.198127
GO:0051642centrosome localization1.35e-021.00e+006.198117
GO:0000339RNA cap binding1.35e-021.00e+006.198117
GO:0000780condensed nuclear chromosome, centromeric region1.35e-021.00e+006.198117
GO:0005832chaperonin-containing T-complex1.35e-021.00e+006.198147
GO:0045814negative regulation of gene expression, epigenetic1.35e-021.00e+006.198117
GO:0051382kinetochore assembly1.35e-021.00e+006.198127
GO:0005829cytosol1.38e-021.00e+001.2028881787
GO:0000086G2/M transition of mitotic cell cycle1.50e-021.00e+003.4062797
GO:0005845mRNA cap binding complex1.55e-021.00e+006.005118
GO:0006450regulation of translational fidelity1.55e-021.00e+006.005118
GO:0010944negative regulation of transcription by competitive promoter binding1.55e-021.00e+006.005118
GO:0010388cullin deneddylation1.55e-021.00e+006.005148
GO:0009948anterior/posterior axis specification1.55e-021.00e+006.005118
GO:0010225response to UV-C1.74e-021.00e+005.836129
GO:0006379mRNA cleavage1.74e-021.00e+005.836129
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process1.74e-021.00e+005.836129
GO:0071354cellular response to interleukin-61.74e-021.00e+005.836119
GO:0048387negative regulation of retinoic acid receptor signaling pathway1.74e-021.00e+005.836129
GO:0032039integrator complex1.74e-021.00e+005.836119
GO:0005515protein binding1.92e-021.00e+000.696131984124
GO:0005095GTPase inhibitor activity1.93e-021.00e+005.6841110
GO:0007049cell cycle2.06e-021.00e+003.16028115
GO:0060766negative regulation of androgen receptor signaling pathway2.12e-021.00e+005.5461411
GO:0008652cellular amino acid biosynthetic process2.12e-021.00e+005.5461211
GO:0008334histone mRNA metabolic process2.12e-021.00e+005.5461111
GO:0000132establishment of mitotic spindle orientation2.31e-021.00e+005.4211212
GO:0035098ESC/E(Z) complex2.50e-021.00e+005.3051113
GO:2000377regulation of reactive oxygen species metabolic process2.50e-021.00e+005.3051113
GO:0006978DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator2.69e-021.00e+005.1981114
GO:0016575histone deacetylation2.69e-021.00e+005.1981214
GO:2000134negative regulation of G1/S transition of mitotic cell cycle2.88e-021.00e+005.0991215
GO:0008135translation factor activity, nucleic acid binding2.88e-021.00e+005.0991415
GO:0000188inactivation of MAPK activity2.88e-021.00e+005.0991115
GO:0007339binding of sperm to zona pellucida2.88e-021.00e+005.0991415
GO:0003887DNA-directed DNA polymerase activity3.07e-021.00e+005.0051216
GO:0044212transcription regulatory region DNA binding3.09e-021.00e+002.846213143
GO:0004712protein serine/threonine/tyrosine kinase activity3.26e-021.00e+004.9181217
GO:0007052mitotic spindle organization3.26e-021.00e+004.9181317
GO:0031667response to nutrient levels3.26e-021.00e+004.9181217
GO:0031047gene silencing by RNA3.45e-021.00e+004.8361218
GO:0032320positive regulation of Ras GTPase activity3.45e-021.00e+004.8361218
GO:0033574response to testosterone3.45e-021.00e+004.8361118
GO:0005739mitochondrion3.53e-021.00e+001.641432659
GO:0006306DNA methylation3.64e-021.00e+004.7581119
GO:0045840positive regulation of mitosis3.82e-021.00e+004.6841120
GO:0006913nucleocytoplasmic transport3.82e-021.00e+004.6841220
GO:0071902positive regulation of protein serine/threonine kinase activity3.82e-021.00e+004.6841220
GO:0010718positive regulation of epithelial to mesenchymal transition3.82e-021.00e+004.6841220
GO:0005720nuclear heterochromatin3.82e-021.00e+004.6841320
GO:0072686mitotic spindle3.82e-021.00e+004.6841220
GO:0071897DNA biosynthetic process3.82e-021.00e+004.6841220
GO:0034660ncRNA metabolic process3.82e-021.00e+004.6841120
GO:0031647regulation of protein stability4.01e-021.00e+004.6131221
GO:0051084'de novo' posttranslational protein folding4.20e-021.00e+004.5461422
GO:0000387spliceosomal snRNP assembly4.20e-021.00e+004.5461122
GO:00063707-methylguanosine mRNA capping4.57e-021.00e+004.4211524
GO:0008180COP9 signalosome4.57e-021.00e+004.4211624
GO:0005876spindle microtubule4.57e-021.00e+004.4211424
GO:0000976transcription regulatory region sequence-specific DNA binding4.76e-021.00e+004.3621325
GO:0009267cellular response to starvation4.94e-021.00e+004.3051126
GO:0005057receptor signaling protein activity4.94e-021.00e+004.3051226
GO:0016567protein ubiquitination5.09e-021.00e+002.451214188
GO:0032091negative regulation of protein binding5.31e-021.00e+004.1981128
GO:0006418tRNA aminoacylation for protein translation5.50e-021.00e+004.1471429
GO:0042752regulation of circadian rhythm5.50e-021.00e+004.1471529
GO:0006446regulation of translational initiation5.50e-021.00e+004.1471229
GO:0006281DNA repair5.83e-021.00e+002.340224203
GO:0045111intermediate filament cytoskeleton5.87e-021.00e+004.0511331
GO:0031490chromatin DNA binding5.87e-021.00e+004.0511131
GO:0000786nucleosome6.42e-021.00e+003.9181234
GO:0007254JNK cascade6.42e-021.00e+003.9181134
GO:0050434positive regulation of viral transcription6.60e-021.00e+003.8761535
GO:0043406positive regulation of MAP kinase activity6.60e-021.00e+003.8761135
GO:0031124mRNA 3'-end processing6.60e-021.00e+003.8761435
GO:0070301cellular response to hydrogen peroxide6.60e-021.00e+003.8761135
GO:0044297cell body6.60e-021.00e+003.8761535
GO:0003743translation initiation factor activity6.97e-021.00e+003.7961837
GO:0006369termination of RNA polymerase II transcription7.15e-021.00e+003.7581538
GO:0019901protein kinase binding7.37e-021.00e+002.14728232
GO:0003684damaged DNA binding7.69e-021.00e+003.6481141
GO:0005730nucleolus7.80e-021.00e+001.0785741217
GO:0001047core promoter binding7.87e-021.00e+003.6131442
GO:0000724double-strand break repair via homologous recombination7.87e-021.00e+003.6131542
GO:0006406mRNA export from nucleus8.23e-021.00e+003.5461744
GO:0010467gene expression8.25e-021.00e+001.527349535
GO:0001570vasculogenesis8.41e-021.00e+003.5141245
GO:0009612response to mechanical stimulus8.59e-021.00e+003.4821246
GO:0000502proteasome complex8.77e-021.00e+003.4511347
GO:0001558regulation of cell growth9.12e-021.00e+003.3911249
GO:0006368transcription elongation from RNA polymerase II promoter9.66e-021.00e+003.3051852
GO:0043565sequence-specific DNA binding9.87e-021.00e+001.90228275
GO:0006338chromatin remodeling1.02e-011.00e+003.2241755
GO:0016311dephosphorylation1.02e-011.00e+003.2241355
GO:0008584male gonad development1.05e-011.00e+003.1731157
GO:0042826histone deacetylase binding1.07e-011.00e+003.1471558
GO:0000785chromatin1.09e-011.00e+003.1231659
GO:0005737cytoplasm1.12e-011.00e+000.64381272633
GO:0006464cellular protein modification process1.12e-011.00e+003.0751461
GO:0030018Z disc1.18e-011.00e+003.0051364
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.19e-011.00e+002.9831765
GO:0030308negative regulation of cell growth1.28e-011.00e+002.8761370
GO:0006325chromatin organization1.28e-011.00e+002.8761470
GO:0051082unfolded protein binding1.28e-011.00e+002.8761570
GO:0001889liver development1.30e-011.00e+002.8561471
GO:0030496midbody1.33e-011.00e+002.8161673
GO:0051726regulation of cell cycle1.33e-011.00e+002.8161373
GO:0001649osteoblast differentiation1.35e-011.00e+002.7961574
GO:0015630microtubule cytoskeleton1.36e-011.00e+002.7771575
GO:0071456cellular response to hypoxia1.38e-011.00e+002.7581276
GO:0006366transcription from RNA polymerase II promoter1.41e-011.00e+001.592223341
GO:0048471perinuclear region of cytoplasm1.43e-011.00e+001.579211344
GO:0005634nucleus1.44e-011.00e+000.51191583246
GO:0005819spindle1.45e-011.00e+002.6841680
GO:0030529ribonucleoprotein complex1.48e-011.00e+002.6481582
GO:0044267cellular protein metabolic process1.48e-011.00e+001.546214352
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.52e-011.00e+002.6131584
GO:0006355regulation of transcription, DNA-templated1.58e-011.00e+001.109331715
GO:0000209protein polyubiquitination1.65e-011.00e+002.4821692
GO:0006511ubiquitin-dependent protein catabolic process1.65e-011.00e+002.4821692
GO:0045893positive regulation of transcription, DNA-templated1.66e-011.00e+001.447221377
GO:0006260DNA replication1.68e-011.00e+002.4511994
GO:0006457protein folding1.73e-011.00e+002.4061597
GO:0006413translational initiation1.76e-011.00e+002.3761699
GO:0034641cellular nitrogen compound metabolic process1.86e-011.00e+002.29115105
GO:0046777protein autophosphorylation1.87e-011.00e+002.27813106
GO:0000790nuclear chromatin1.92e-011.00e+002.23719109
GO:0042981regulation of apoptotic process1.97e-011.00e+002.19814112
GO:0043005neuron projection1.99e-011.00e+002.18516113
GO:0000287magnesium ion binding2.02e-011.00e+002.16014115
GO:0016032viral process2.02e-011.00e+001.264230428
GO:0004672protein kinase activity2.17e-011.00e+002.04015125
GO:0000398mRNA splicing, via spliceosome2.22e-011.00e+002.005115128
GO:0031625ubiquitin protein ligase binding2.37e-011.00e+001.89717138
GO:0005524ATP binding2.48e-011.00e+000.790337892
GO:0016874ligase activity2.49e-011.00e+001.816111146
GO:0001701in utero embryonic development2.61e-011.00e+001.73917154
GO:0005874microtubule2.74e-011.00e+001.657110163
GO:0008380RNA splicing2.77e-011.00e+001.639121165
GO:0007067mitotic nuclear division2.77e-011.00e+001.63919165
GO:0003677DNA binding2.78e-011.00e+000.703352947
GO:0016071mRNA metabolic process2.84e-011.00e+001.596110170
GO:0006412translation2.95e-011.00e+001.530112178
GO:0016070RNA metabolic process3.09e-011.00e+001.451110188
GO:0005743mitochondrial inner membrane3.21e-011.00e+001.38319197
GO:0004674protein serine/threonine kinase activity3.21e-011.00e+001.38318197
GO:0035556intracellular signal transduction3.24e-011.00e+001.36915199
GO:0030154cell differentiation3.31e-011.00e+001.33315204
GO:0019899enzyme binding3.39e-011.00e+001.29117210
GO:0007165signal transduction3.41e-011.00e+000.734224618
GO:0005813centrosome3.48e-011.00e+001.244110217
GO:0006351transcription, DNA-templated3.50e-011.00e+000.5193471076
GO:0008283cell proliferation3.76e-011.00e+001.10518239
GO:0006508proteolysis4.06e-011.00e+000.961111264
GO:0046982protein heterodimerization activity4.07e-011.00e+000.956111265
GO:0008270zinc ion binding4.19e-011.00e+000.500239727
GO:0008285negative regulation of cell proliferation4.21e-011.00e+000.892111277
GO:0008284positive regulation of cell proliferation4.24e-011.00e+000.88118279
GO:0006468protein phosphorylation4.49e-011.00e+000.77216301
GO:0044822poly(A) RNA binding4.68e-011.00e+000.363245799
GO:0043066negative regulation of apoptotic process4.71e-011.00e+000.67518322
GO:0005509calcium ion binding5.02e-011.00e+000.55019351
GO:0042802identical protein binding5.05e-011.00e+000.538115354
GO:0046872metal ion binding5.55e-011.00e+000.138224934
GO:0006915apoptotic process5.59e-011.00e+000.322115411
GO:0042803protein homodimerization activity5.74e-011.00e+000.264113428
GO:0005887integral component of plasma membrane6.85e-011.00e+00-0.16218575
GO:0003700sequence-specific DNA binding transcription factor activity6.89e-011.00e+00-0.179122582
GO:0045944positive regulation of transcription from RNA polymerase II promoter7.27e-011.00e+00-0.325129644
GO:0044281small molecule metabolic process8.21e-011.00e+00-0.716135844
GO:0070062extracellular vesicular exosome8.54e-011.00e+00-0.6752511641
GO:0016020membrane9.19e-011.00e+00-1.2321561207
GO:0005886plasma membrane9.78e-011.00e+00-1.7951461784