reg-snw-55153

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.231 1.99e-07 3.86e-02 2.95e-02
chia-screen-data-Fav-reg-snw-55153 subnetwork

Genes (17)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
AGPS 8540 23-2.4242.41027-YesYes
RAPGEF2 9693 2-1.8922.24611---
SLC7A5P1 81893 4-3.2172.4454-Yes-
CBLL1 79872 9-1.8972.44538TF--
PAPOLA 10914 9-1.9962.45519---
EPRS 2058 3-1.2862.286139TF--
NCBP1 4686 41-2.5102.45944-YesYes
SYNCRIP 10492 42-2.4012.503144TFYesYes
SUV39H2 79723 27-2.3072.41021-YesYes
ALKBH8 91801 8-2.1472.4105-Yes-
CASP2 835 4-2.0072.44547TFYes-
[ SDAD1 ] 55153 1-0.8172.2313---
ETF1 2107 35-2.8292.5036-YesYes
GSPT1 2935 32-2.3132.50317-YesYes
CCT7 10574 40-2.3352.45938-Yes-
CPSF3 51692 43-2.6862.50331-YesYes
HNRNPU 3192 39-2.8692.64433-Yes-

Interactions (18)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
CASP2 835 SLC7A5P1 81893 pd > reg.ITFP.txt: no annot
SYNCRIP 10492 PAPOLA 10914 pd > reg.ITFP.txt: no annot
CASP2 835 RAPGEF2 9693 pd > reg.ITFP.txt: no annot
EPRS 2058 HNRNPU 3192 pd > reg.ITFP.txt: no annot
EPRS 2058 SDAD1 55153 pd > reg.ITFP.txt: no annot
CASP2 835 SDAD1 55153 pd > reg.ITFP.txt: no annot
NCBP1 4686 CBLL1 79872 pd < reg.ITFP.txt: no annot
AGPS 8540 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
SYNCRIP 10492 SUV39H2 79723 pd > reg.ITFP.txt: no annot
EPRS 2058 CCT7 10574 pd > reg.ITFP.txt: no annot
SYNCRIP 10492 ALKBH8 91801 pd > reg.ITFP.txt: no annot
SYNCRIP 10492 SDAD1 55153 pd > reg.ITFP.txt: no annot
CASP2 835 CBLL1 79872 pd <> reg.ITFP.txt: no annot
EPRS 2058 NCBP1 4686 pd > reg.ITFP.txt: no annot
EPRS 2058 SYNCRIP 10492 pd <> reg.ITFP.txt: no annot
ETF1 2107 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
GSPT1 2935 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
SYNCRIP 10492 CPSF3 51692 pd > reg.ITFP.txt: no annot

Related GO terms (224)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0030529ribonucleoprotein complex2.11e-072.06e-035.1305582
GO:0000398mRNA splicing, via spliceosome1.95e-061.91e-024.488515128
GO:0003723RNA binding2.41e-062.36e-023.803622247
GO:0003747translation release factor activity2.85e-062.79e-029.166222
GO:0008380RNA splicing6.81e-066.65e-024.122521165
GO:0097452GAIT complex1.71e-051.67e-018.166224
GO:0031124mRNA 3'-end processing2.77e-052.71e-015.6223435
GO:0070934CRD-mediated mRNA stabilization2.84e-052.78e-017.844225
GO:0006369termination of RNA polymerase II transcription3.56e-053.48e-015.5033538
GO:0070937CRD-mediated mRNA stability complex4.26e-054.16e-017.581226
GO:0006379mRNA cleavage1.02e-049.96e-016.996229
GO:0006479protein methylation1.55e-041.00e+006.7072211
GO:0010467gene expression1.94e-041.00e+002.688649535
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay3.83e-041.00e+004.3593584
GO:0071346cellular response to interferon-gamma5.32e-041.00e+005.8442220
GO:0017148negative regulation of translation1.46e-031.00e+005.1222533
GO:0048022negative regulation of melanin biosynthetic process1.74e-031.00e+009.166111
GO:0016149translation release factor activity, codon specific1.74e-031.00e+009.166111
GO:0016300tRNA (uracil) methyltransferase activity1.74e-031.00e+009.166111
GO:0008609alkylglycerone-phosphate synthase activity1.74e-031.00e+009.166111
GO:0008079translation termination factor activity1.74e-031.00e+009.166111
GO:0001554luteolysis1.74e-031.00e+009.166111
GO:0006396RNA processing2.14e-031.00e+004.8442440
GO:0006406mRNA export from nucleus2.59e-031.00e+004.7072744
GO:1901888regulation of cell junction assembly3.48e-031.00e+008.166112
GO:0071880adenylate cyclase-activating adrenergic receptor signaling pathway3.48e-031.00e+008.166112
GO:0006433prolyl-tRNA aminoacylation3.48e-031.00e+008.166112
GO:0004818glutamate-tRNA ligase activity3.48e-031.00e+008.166112
GO:0004827proline-tRNA ligase activity3.48e-031.00e+008.166112
GO:0005846nuclear cap binding complex3.48e-031.00e+008.166112
GO:0008611ether lipid biosynthetic process3.48e-031.00e+008.166112
GO:0031547brain-derived neurotrophic factor receptor signaling pathway3.48e-031.00e+008.166112
GO:0006424glutamyl-tRNA aminoacylation3.48e-031.00e+008.166112
GO:0005515protein binding4.45e-031.00e+000.857131984124
GO:0071013catalytic step 2 spliceosome4.91e-031.00e+004.2352561
GO:0008762UDP-N-acetylmuramate dehydrogenase activity5.21e-031.00e+007.581113
GO:0036123histone H3-K9 dimethylation5.21e-031.00e+007.581113
GO:0050774negative regulation of dendrite morphogenesis5.21e-031.00e+007.581113
GO:0046582Rap GTPase activator activity5.21e-031.00e+007.581113
GO:0005088Ras guanyl-nucleotide exchange factor activity5.21e-031.00e+007.581113
GO:2000670positive regulation of dendritic cell apoptotic process5.21e-031.00e+007.581113
GO:0002098tRNA wobble uridine modification5.21e-031.00e+007.581113
GO:0017034Rap guanyl-nucleotide exchange factor activity5.21e-031.00e+007.581113
GO:0031697beta-1 adrenergic receptor binding5.21e-031.00e+007.581113
GO:0006415translational termination5.23e-031.00e+004.1892263
GO:0003407neural retina development6.95e-031.00e+007.166124
GO:0045292mRNA cis splicing, via spliceosome6.95e-031.00e+007.166114
GO:0004652polynucleotide adenylyltransferase activity6.95e-031.00e+007.166114
GO:0031442positive regulation of mRNA 3'-end processing6.95e-031.00e+007.166114
GO:0006449regulation of translational termination6.95e-031.00e+007.166114
GO:0000055ribosomal large subunit export from nucleus6.95e-031.00e+007.166114
GO:2000481positive regulation of cAMP-dependent protein kinase activity6.95e-031.00e+007.166114
GO:0006333chromatin assembly or disassembly6.95e-031.00e+007.166114
GO:0036124histone H3-K9 trimethylation6.95e-031.00e+007.166124
GO:0043631RNA polyadenylation6.95e-031.00e+007.166114
GO:0035613RNA stem-loop binding6.95e-031.00e+007.166114
GO:0001649osteoblast differentiation7.16e-031.00e+003.9562574
GO:0004521endoribonuclease activity8.68e-031.00e+006.844115
GO:0008610lipid biosynthetic process8.68e-031.00e+006.844115
GO:0038180nerve growth factor signaling pathway8.68e-031.00e+006.844115
GO:0006398histone mRNA 3'-end processing8.68e-031.00e+006.844115
GO:0097153cysteine-type endopeptidase activity involved in apoptotic process8.68e-031.00e+006.844115
GO:0021884forebrain neuron development8.68e-031.00e+006.844115
GO:0071204histone pre-mRNA 3'end processing complex8.68e-031.00e+006.844115
GO:0044822poly(A) RNA binding9.76e-031.00e+001.846545799
GO:0042754negative regulation of circadian rhythm1.04e-021.00e+006.581126
GO:0071321cellular response to cGMP1.04e-021.00e+006.581116
GO:0046974histone methyltransferase activity (H3-K9 specific)1.04e-021.00e+006.581116
GO:2001224positive regulation of neuron migration1.04e-021.00e+006.581116
GO:0035234ectopic germ cell programmed cell death1.04e-021.00e+006.581116
GO:0019992diacylglycerol binding1.04e-021.00e+006.581116
GO:0002199zona pellucida receptor complex1.21e-021.00e+006.359147
GO:0007140male meiosis1.21e-021.00e+006.359117
GO:0032854positive regulation of Rap GTPase activity1.21e-021.00e+006.359117
GO:00084095'-3' exonuclease activity1.21e-021.00e+006.359127
GO:2001214positive regulation of vasculogenesis1.21e-021.00e+006.359127
GO:0000339RNA cap binding1.21e-021.00e+006.359117
GO:0005832chaperonin-containing T-complex1.21e-021.00e+006.359147
GO:0043281regulation of cysteine-type endopeptidase activity involved in apoptotic process1.21e-021.00e+006.359117
GO:0032486Rap protein signal transduction1.21e-021.00e+006.359117
GO:0016020membrane1.30e-021.00e+001.5146561207
GO:0030553cGMP binding1.38e-021.00e+006.166118
GO:0005845mRNA cap binding complex1.38e-021.00e+006.166118
GO:0016706oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors1.38e-021.00e+006.166118
GO:0071949FAD binding1.38e-021.00e+006.166118
GO:0005654nucleoplasm1.43e-021.00e+001.713568876
GO:0030488tRNA methylation1.56e-021.00e+005.996129
GO:0021591ventricular system development1.56e-021.00e+005.996119
GO:0005847mRNA cleavage and polyadenylation specificity factor complex1.56e-021.00e+005.996139
GO:0008143poly(A) binding1.73e-021.00e+005.8441210
GO:0061028establishment of endothelial barrier1.73e-021.00e+005.8441110
GO:0042273ribosomal large subunit biogenesis1.90e-021.00e+005.7071111
GO:0043950positive regulation of cAMP-mediated signaling1.90e-021.00e+005.7071111
GO:0008334histone mRNA metabolic process1.90e-021.00e+005.7071111
GO:0045807positive regulation of endocytosis1.90e-021.00e+005.7071111
GO:1990090cellular response to nerve growth factor stimulus1.90e-021.00e+005.7071111
GO:0006366transcription from RNA polymerase II promoter1.99e-021.00e+002.337323341
GO:0005739mitochondrion2.41e-021.00e+001.802432659
GO:0030552cAMP binding2.41e-021.00e+005.3591114
GO:0050699WW domain binding2.41e-021.00e+005.3591114
GO:0097194execution phase of apoptosis2.58e-021.00e+005.2591115
GO:0007339binding of sperm to zona pellucida2.58e-021.00e+005.2591415
GO:0016485protein processing2.75e-021.00e+005.1661116
GO:0005782peroxisomal matrix2.75e-021.00e+005.1661116
GO:0043022ribosome binding2.92e-021.00e+005.0781217
GO:0019933cAMP-mediated signaling2.92e-021.00e+005.0781117
GO:0031047gene silencing by RNA3.09e-021.00e+004.9961218
GO:0006378mRNA polyadenylation3.09e-021.00e+004.9961318
GO:0032320positive regulation of Ras GTPase activity3.09e-021.00e+004.9961218
GO:0036464cytoplasmic ribonucleoprotein granule3.26e-021.00e+004.9181119
GO:2001235positive regulation of apoptotic signaling pathway3.26e-021.00e+004.9181219
GO:0005720nuclear heterochromatin3.43e-021.00e+004.8441320
GO:0034660ncRNA metabolic process3.43e-021.00e+004.8441120
GO:0016071mRNA metabolic process3.45e-021.00e+002.757210170
GO:0048167regulation of synaptic plasticity3.60e-021.00e+004.7741121
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic3.60e-021.00e+004.7741221
GO:0051084'de novo' posttranslational protein folding3.76e-021.00e+004.7071422
GO:0000387spliceosomal snRNP assembly3.76e-021.00e+004.7071122
GO:0000049tRNA binding3.93e-021.00e+004.6421223
GO:0007162negative regulation of cell adhesion4.10e-021.00e+004.5811224
GO:00063707-methylguanosine mRNA capping4.10e-021.00e+004.5811524
GO:0016070RNA metabolic process4.15e-021.00e+002.611210188
GO:0000976transcription regulatory region sequence-specific DNA binding4.27e-021.00e+004.5221325
GO:0030145manganese ion binding4.43e-021.00e+004.4661326
GO:0006418tRNA aminoacylation for protein translation4.93e-021.00e+004.3081429
GO:0005778peroxisomal membrane4.93e-021.00e+004.3081329
GO:0006446regulation of translational initiation4.93e-021.00e+004.3081229
GO:0097192extrinsic apoptotic signaling pathway in absence of ligand5.27e-021.00e+004.2121131
GO:0001568blood vessel development5.27e-021.00e+004.2121131
GO:0071320cellular response to cAMP5.60e-021.00e+004.1221133
GO:0032092positive regulation of protein binding5.76e-021.00e+004.0781234
GO:0050434positive regulation of viral transcription5.93e-021.00e+004.0371535
GO:0044297cell body5.93e-021.00e+004.0371535
GO:0004197cysteine-type endopeptidase activity6.25e-021.00e+003.9561137
GO:0045860positive regulation of protein kinase activity6.25e-021.00e+003.9561237
GO:0005524ATP binding6.30e-021.00e+001.365437892
GO:0048511rhythmic process6.42e-021.00e+003.9181538
GO:0010976positive regulation of neuron projection development6.58e-021.00e+003.8811139
GO:0043525positive regulation of neuron apoptotic process6.91e-021.00e+003.8081141
GO:0000775chromosome, centromeric region6.91e-021.00e+003.8081641
GO:0008630intrinsic apoptotic signaling pathway in response to DNA damage7.07e-021.00e+003.7741242
GO:0005829cytosol7.42e-021.00e+000.9486881787
GO:0000151ubiquitin ligase complex8.04e-021.00e+003.5811448
GO:0005777peroxisome8.36e-021.00e+003.5221250
GO:0006368transcription elongation from RNA polymerase II promoter8.68e-021.00e+003.4661852
GO:0030165PDZ domain binding8.68e-021.00e+003.4661352
GO:0007218neuropeptide signaling pathway8.84e-021.00e+003.4381253
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest8.84e-021.00e+003.4381353
GO:0005770late endosome9.00e-021.00e+003.4111254
GO:0006338chromatin remodeling9.16e-021.00e+003.3851755
GO:0071260cellular response to mechanical stimulus9.16e-021.00e+003.3851255
GO:0031175neuron projection development9.16e-021.00e+003.3851155
GO:0000165MAPK cascade9.64e-021.00e+003.3081358
GO:0000785chromatin9.80e-021.00e+003.2831659
GO:0055114oxidation-reduction process9.88e-021.00e+001.89929308
GO:0016337single organismal cell-cell adhesion1.03e-011.00e+003.2121362
GO:0001764neuron migration1.11e-011.00e+003.1001167
GO:0051082unfolded protein binding1.15e-011.00e+003.0371570
GO:0044267cellular protein metabolic process1.24e-011.00e+001.707214352
GO:0071456cellular response to hypoxia1.24e-011.00e+002.9181276
GO:0070374positive regulation of ERK1 and ERK2 cascade1.24e-011.00e+002.9181176
GO:0042802identical protein binding1.25e-011.00e+001.698215354
GO:0008270zinc ion binding1.28e-011.00e+001.245339727
GO:0097190apoptotic signaling pathway1.35e-011.00e+002.7911183
GO:0045202synapse1.35e-011.00e+002.7911383
GO:0044255cellular lipid metabolic process1.44e-011.00e+002.6901289
GO:0030036actin cytoskeleton organization1.46e-011.00e+002.6741490
GO:0005737cytoplasm1.47e-011.00e+000.61171272633
GO:0006461protein complex assembly1.47e-011.00e+002.6581291
GO:0005506iron ion binding1.49e-011.00e+002.6421492
GO:0005730nucleolus1.53e-011.00e+000.9174741217
GO:0006457protein folding1.56e-011.00e+002.5661597
GO:0007568aging1.56e-011.00e+002.5661397
GO:0030335positive regulation of cell migration1.62e-011.00e+002.50812101
GO:0005911cell-cell junction1.67e-011.00e+002.46613104
GO:0016032viral process1.69e-011.00e+001.424230428
GO:0043005neuron projection1.80e-011.00e+002.34616113
GO:0000287magnesium ion binding1.83e-011.00e+002.32014115
GO:0007420brain development1.88e-011.00e+002.27113119
GO:0003924GTPase activity1.88e-011.00e+002.27117119
GO:0006974cellular response to DNA damage stimulus1.91e-011.00e+002.247111121
GO:0000082G1/S transition of mitotic cell cycle1.97e-011.00e+002.20014125
GO:0006184GTP catabolic process2.04e-011.00e+002.14417130
GO:0019904protein domain specific binding2.04e-011.00e+002.14414130
GO:0005622intracellular2.25e-011.00e+001.98612145
GO:0016874ligase activity2.26e-011.00e+001.976111146
GO:0004871signal transducer activity2.29e-011.00e+001.95614148
GO:0005874microtubule2.49e-011.00e+001.817110163
GO:0043025neuronal cell body2.60e-011.00e+001.74813171
GO:0007264small GTPase mediated signal transduction2.64e-011.00e+001.72318174
GO:0000166nucleotide binding2.66e-011.00e+001.707113176
GO:0006412translation2.69e-011.00e+001.690112178
GO:0004842ubiquitin-protein transferase activity2.70e-011.00e+001.682117179
GO:0016567protein ubiquitination2.82e-011.00e+001.611114188
GO:0005525GTP binding2.93e-011.00e+001.544112197
GO:0048011neurotrophin TRK receptor signaling pathway2.96e-011.00e+001.52918199
GO:0035556intracellular signal transduction2.96e-011.00e+001.52915199
GO:0043065positive regulation of apoptotic process2.99e-011.00e+001.50817202
GO:0015031protein transport3.01e-011.00e+001.501110203
GO:0030154cell differentiation3.02e-011.00e+001.49415204
GO:0043234protein complex3.09e-011.00e+001.452113210
GO:0019899enzyme binding3.09e-011.00e+001.45217210
GO:0043231intracellular membrane-bounded organelle3.19e-011.00e+001.39818218
GO:0007186G-protein coupled receptor signaling pathway3.32e-011.00e+001.32714229
GO:0019901protein kinase binding3.36e-011.00e+001.30818232
GO:0003682chromatin binding3.59e-011.00e+001.189115252
GO:0006508proteolysis3.73e-011.00e+001.122111264
GO:0008285negative regulation of cell proliferation3.87e-011.00e+001.052111277
GO:0009986cell surface4.02e-011.00e+000.98115291
GO:0003674molecular_function4.09e-011.00e+000.95214297
GO:0045892negative regulation of transcription, DNA-templated4.30e-011.00e+000.858117317
GO:0048471perinuclear region of cytoplasm4.57e-011.00e+000.740111344
GO:0005509calcium ion binding4.64e-011.00e+000.71119351
GO:0005783endoplasmic reticulum4.92e-011.00e+000.592112381
GO:0006915apoptotic process5.19e-011.00e+000.483115411
GO:0005634nucleus5.19e-011.00e+000.08661583246
GO:0000122negative regulation of transcription from RNA polymerase II promoter5.57e-011.00e+000.333129456
GO:0005887integral component of plasma membrane6.44e-011.00e+00-0.00118575
GO:0044281small molecule metabolic process7.85e-011.00e+00-0.555135844
GO:0046872metal ion binding8.19e-011.00e+00-0.701124934
GO:0003677DNA binding8.24e-011.00e+00-0.721152947
GO:0005886plasma membrane8.45e-011.00e+00-0.6352461784
GO:0006351transcription, DNA-templated8.63e-011.00e+00-0.9061471076
GO:0070062extracellular vesicular exosome9.56e-011.00e+00-1.5141511641