reg-snw-27130

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.286 1.02e-07 2.70e-02 2.12e-02
chia-screen-data-Fav-reg-snw-27130 subnetwork

Genes (18)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
NDUFA4L2 56901 44-2.4772.45921-Yes-
PHB 5245 82-2.7432.68936-YesYes
SCD 6319 1-1.7152.28613---
VARS 7407 60-2.3662.689124TFYes-
NUP160 23279 3-1.5292.38750---
[ INVS ] 27130 1-1.1402.28629TF--
FBXO22 26263 36-1.7392.459208TF--
EPRS 2058 3-1.2862.286139TF--
TPR 7175 10-2.6382.44536TFYesYes
NCBP1 4686 41-2.5102.45944-YesYes
EIF2S2 8894 40-2.9992.45922-YesYes
SYNCRIP 10492 42-2.4012.503144TFYesYes
CENPQ 55166 20-2.1372.45916-Yes-
CCT7 10574 40-2.3352.45938-Yes-
HNRNPU 3192 39-2.8692.64433-Yes-
GPS1 2873 86-3.6212.68936TFYesYes
POLH 5429 36-2.5862.45924-YesYes
PSPH 5723 14-2.0632.38711-Yes-

Interactions (24)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
NCBP1 4686 FBXO22 26263 pd < reg.ITFP.txt: no annot
EPRS 2058 HNRNPU 3192 pd > reg.ITFP.txt: no annot
FBXO22 26263 INVS 27130 pd <> reg.ITFP.txt: no annot
NCBP1 4686 TPR 7175 pd < reg.ITFP.txt: no annot
EPRS 2058 SCD 6319 pd > reg.ITFP.txt: no annot
VARS 7407 FBXO22 26263 pd <> reg.ITFP.txt: no annot
NCBP1 4686 INVS 27130 pd < reg.ITFP.txt: no annot
PHB 5245 VARS 7407 pd < reg.ITFP.txt: no annot
EPRS 2058 NCBP1 4686 pd > reg.ITFP.txt: no annot
SCD 6319 INVS 27130 pd < reg.ITFP.txt: no annot
EIF2S2 8894 FBXO22 26263 pd < reg.ITFP.txt: no annot
EPRS 2058 NUP160 23279 pd > reg.ITFP.txt: no annot
PSPH 5723 FBXO22 26263 pd < reg.ITFP.txt: no annot
EPRS 2058 SYNCRIP 10492 pd <> reg.ITFP.txt: no annot
FBXO22 26263 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
EPRS 2058 INVS 27130 pd <> reg.ITFP.txt: no annot
NUP160 23279 FBXO22 26263 pd < reg.ITFP.txt: no annot
PHB 5245 FBXO22 26263 pd < reg.ITFP.txt: no annot
POLH 5429 FBXO22 26263 pd < reg.ITFP.txt: no annot
NUP160 23279 INVS 27130 pd < reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot
FBXO22 26263 CENPQ 55166 pd > reg.ITFP.txt: no annot
CCT7 10574 FBXO22 26263 pd < reg.ITFP.txt: no annot
EPRS 2058 CCT7 10574 pd > reg.ITFP.txt: no annot

Related GO terms (218)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0030529ribonucleoprotein complex1.29e-051.26e-014.7264582
GO:0097452GAIT complex1.92e-051.88e-018.083224
GO:0070934CRD-mediated mRNA stabilization3.20e-053.12e-017.762225
GO:0070937CRD-mediated mRNA stability complex4.79e-054.68e-017.499226
GO:0005487nucleocytoplasmic transporter activity1.75e-041.00e+006.6242211
GO:0001649osteoblast differentiation3.14e-041.00e+004.4593574
GO:0071346cellular response to interferon-gamma5.98e-041.00e+005.7622220
GO:0005654nucleoplasm6.00e-041.00e+002.116768876
GO:0003723RNA binding9.24e-041.00e+003.135422247
GO:0010827regulation of glucose transport9.39e-041.00e+005.4402725
GO:0006418tRNA aminoacylation for protein translation1.27e-031.00e+005.2252429
GO:0007077mitotic nuclear envelope disassembly1.54e-031.00e+005.0832932
GO:0000398mRNA splicing, via spliceosome1.55e-031.00e+003.668315128
GO:0017148negative regulation of translation1.64e-031.00e+005.0392533
GO:0004832valine-tRNA ligase activity1.84e-031.00e+009.083111
GO:1901673regulation of spindle assembly involved in mitosis1.84e-031.00e+009.083111
GO:0004768stearoyl-CoA 9-desaturase activity1.84e-031.00e+009.083111
GO:0043578nuclear matrix organization1.84e-031.00e+009.083111
GO:0010965regulation of mitotic sister chromatid separation1.84e-031.00e+009.083111
GO:0006404RNA import into nucleus1.84e-031.00e+009.083111
GO:0006438valyl-tRNA aminoacylation1.84e-031.00e+009.083111
GO:0031453positive regulation of heterochromatin assembly1.84e-031.00e+009.083111
GO:0008645hexose transport1.95e-031.00e+004.9142836
GO:0010467gene expression2.29e-031.00e+002.342549535
GO:0006396RNA processing2.40e-031.00e+004.7622440
GO:0006406mRNA export from nucleus2.90e-031.00e+004.6242744
GO:0008380RNA splicing3.21e-031.00e+003.302321165
GO:0015758glucose transport3.44e-031.00e+004.4992848
GO:0000189MAPK import into nucleus3.68e-031.00e+008.083112
GO:0048742regulation of skeletal muscle fiber development3.68e-031.00e+008.083112
GO:0031990mRNA export from nucleus in response to heat stress3.68e-031.00e+008.083112
GO:0006433prolyl-tRNA aminoacylation3.68e-031.00e+008.083112
GO:0004647phosphoserine phosphatase activity3.68e-031.00e+008.083112
GO:0004818glutamate-tRNA ligase activity3.68e-031.00e+008.083112
GO:0004827proline-tRNA ligase activity3.68e-031.00e+008.083112
GO:0042306regulation of protein import into nucleus3.68e-031.00e+008.083112
GO:0005846nuclear cap binding complex3.68e-031.00e+008.083112
GO:0002176male germ cell proliferation3.68e-031.00e+008.083112
GO:0070840dynein complex binding3.68e-031.00e+008.083112
GO:0046832negative regulation of RNA export from nucleus3.68e-031.00e+008.083112
GO:0006424glutamyl-tRNA aminoacylation3.68e-031.00e+008.083112
GO:0005643nuclear pore3.88e-031.00e+004.41121251
GO:0000776kinetochore4.50e-031.00e+004.3022855
GO:0071013catalytic step 2 spliceosome5.51e-031.00e+004.1532561
GO:0005850eukaryotic translation initiation factor 2 complex5.52e-031.00e+007.499123
GO:0006405RNA export from nucleus5.52e-031.00e+007.499113
GO:0010793regulation of mRNA export from nucleus5.52e-031.00e+007.499113
GO:0006563L-serine metabolic process5.52e-031.00e+007.499113
GO:0016032viral process6.82e-031.00e+002.342430428
GO:0045292mRNA cis splicing, via spliceosome7.35e-031.00e+007.083114
GO:0031442positive regulation of mRNA 3'-end processing7.35e-031.00e+007.083114
GO:0006290pyrimidine dimer repair7.35e-031.00e+007.083124
GO:0006999nuclear pore organization7.35e-031.00e+007.083114
GO:0060971embryonic heart tube left/right pattern formation7.35e-031.00e+007.083114
GO:0006564L-serine biosynthetic process7.35e-031.00e+007.083114
GO:0035613RNA stem-loop binding7.35e-031.00e+007.083114
GO:0070849response to epidermal growth factor7.35e-031.00e+007.083114
GO:0044615nuclear pore nuclear basket7.35e-031.00e+007.083114
GO:0046825regulation of protein export from nucleus9.18e-031.00e+006.762115
GO:0043495protein anchor9.18e-031.00e+006.762115
GO:0006282regulation of DNA repair9.18e-031.00e+006.762125
GO:2000323negative regulation of glucocorticoid receptor signaling pathway9.18e-031.00e+006.762115
GO:0002161aminoacyl-tRNA editing activity9.18e-031.00e+006.762115
GO:0071204histone pre-mRNA 3'end processing complex9.18e-031.00e+006.762115
GO:0005829cytosol9.48e-031.00e+001.2808881787
GO:0005635nuclear envelope1.00e-021.00e+003.7082683
GO:0050847progesterone receptor signaling pathway1.10e-021.00e+006.499126
GO:0090267positive regulation of mitotic cell cycle spindle assembly checkpoint1.10e-021.00e+006.499116
GO:0044822poly(A) RNA binding1.26e-021.00e+001.763545799
GO:0002199zona pellucida receptor complex1.28e-021.00e+006.276147
GO:0000731DNA synthesis involved in DNA repair1.28e-021.00e+006.276117
GO:0006301postreplication repair1.28e-021.00e+006.276127
GO:0000339RNA cap binding1.28e-021.00e+006.276117
GO:0005832chaperonin-containing T-complex1.28e-021.00e+006.276147
GO:0005868cytoplasmic dynein complex1.28e-021.00e+006.276117
GO:0005845mRNA cap binding complex1.47e-021.00e+006.083118
GO:0042405nuclear inclusion body1.47e-021.00e+006.083118
GO:0051292nuclear pore complex assembly1.47e-021.00e+006.083148
GO:0006450regulation of translational fidelity1.47e-021.00e+006.083118
GO:0010944negative regulation of transcription by competitive promoter binding1.47e-021.00e+006.083118
GO:0010388cullin deneddylation1.47e-021.00e+006.083148
GO:0035457cellular response to interferon-alpha1.47e-021.00e+006.083118
GO:0031080nuclear pore outer ring1.65e-021.00e+005.914129
GO:0010225response to UV-C1.65e-021.00e+005.914129
GO:0006379mRNA cleavage1.65e-021.00e+005.914129
GO:0045947negative regulation of translational initiation1.65e-021.00e+005.914119
GO:0071354cellular response to interleukin-61.65e-021.00e+005.914119
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process1.65e-021.00e+005.914129
GO:0016020membrane1.75e-021.00e+001.4316561207
GO:0005095GTPase inhibitor activity1.83e-021.00e+005.7621110
GO:0008143poly(A) binding1.83e-021.00e+005.7621210
GO:0000278mitotic cell cycle1.88e-021.00e+002.374328314
GO:0060766negative regulation of androgen receptor signaling pathway2.01e-021.00e+005.6241411
GO:0008652cellular amino acid biosynthetic process2.01e-021.00e+005.6241211
GO:0051019mitogen-activated protein kinase binding2.01e-021.00e+005.6241111
GO:0008334histone mRNA metabolic process2.01e-021.00e+005.6241111
GO:0090316positive regulation of intracellular protein transport2.01e-021.00e+005.6241111
GO:0046827positive regulation of protein export from nucleus2.01e-021.00e+005.6241111
GO:0042307positive regulation of protein import into nucleus2.19e-021.00e+005.4991312
GO:0034399nuclear periphery2.19e-021.00e+005.4991312
GO:0016575histone deacetylation2.55e-021.00e+005.2761214
GO:0008135translation factor activity, nucleic acid binding2.73e-021.00e+005.1771415
GO:0000188inactivation of MAPK activity2.73e-021.00e+005.1771115
GO:0007339binding of sperm to zona pellucida2.73e-021.00e+005.1771415
GO:0003887DNA-directed DNA polymerase activity2.91e-021.00e+005.0831216
GO:0031016pancreas development2.91e-021.00e+005.0831116
GO:0005739mitochondrion2.94e-021.00e+001.719432659
GO:0031667response to nutrient levels3.09e-021.00e+004.9961217
GO:0005737cytoplasm3.12e-021.00e+000.89191272633
GO:0005515protein binding3.20e-021.00e+000.659121984124
GO:0006611protein export from nucleus3.27e-021.00e+004.9141118
GO:0031047gene silencing by RNA3.27e-021.00e+004.9141218
GO:0033574response to testosterone3.27e-021.00e+004.9141118
GO:0036464cytoplasmic ribonucleoprotein granule3.45e-021.00e+004.8361119
GO:0005874microtubule3.56e-021.00e+002.735210163
GO:0015631tubulin binding3.63e-021.00e+004.7621120
GO:0006913nucleocytoplasmic transport3.63e-021.00e+004.7621220
GO:0034080CENP-A containing nucleosome assembly3.63e-021.00e+004.7621220
GO:0072686mitotic spindle3.63e-021.00e+004.7621220
GO:0071897DNA biosynthetic process3.63e-021.00e+004.7621220
GO:0034660ncRNA metabolic process3.63e-021.00e+004.7621120
GO:0031647regulation of protein stability3.80e-021.00e+004.6911221
GO:0019221cytokine-mediated signaling pathway3.92e-021.00e+002.657210172
GO:0006606protein import into nucleus3.98e-021.00e+004.6241322
GO:0051084'de novo' posttranslational protein folding3.98e-021.00e+004.6241422
GO:0000387spliceosomal snRNP assembly3.98e-021.00e+004.6241122
GO:0034605cellular response to heat3.98e-021.00e+004.6241122
GO:00063707-methylguanosine mRNA capping4.34e-021.00e+004.4991524
GO:0008180COP9 signalosome4.34e-021.00e+004.4991624
GO:0007094mitotic spindle assembly checkpoint4.51e-021.00e+004.4401425
GO:0005975carbohydrate metabolic process4.52e-021.00e+002.544210186
GO:0009267cellular response to starvation4.69e-021.00e+004.3831126
GO:0006633fatty acid biosynthetic process4.69e-021.00e+004.3831126
GO:0031072heat shock protein binding5.04e-021.00e+004.2761128
GO:0006446regulation of translational initiation5.22e-021.00e+004.2251229
GO:0019898extrinsic component of membrane5.39e-021.00e+004.1771130
GO:0045111intermediate filament cytoskeleton5.57e-021.00e+004.1291331
GO:0007254JNK cascade6.09e-021.00e+003.9961134
GO:0050434positive regulation of viral transcription6.26e-021.00e+003.9541535
GO:0031124mRNA 3'-end processing6.26e-021.00e+003.9541435
GO:0044297cell body6.26e-021.00e+003.9541535
GO:0003743translation initiation factor activity6.61e-021.00e+003.8741837
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process6.78e-021.00e+003.8361438
GO:0006369termination of RNA polymerase II transcription6.78e-021.00e+003.8361538
GO:0000775chromosome, centromeric region7.30e-021.00e+003.7261641
GO:0003684damaged DNA binding7.30e-021.00e+003.7261141
GO:0005524ATP binding7.53e-021.00e+001.283437892
GO:0009612response to mechanical stimulus8.15e-021.00e+003.5601246
GO:0005929cilium8.33e-021.00e+003.5291247
GO:0006334nucleosome assembly9.00e-021.00e+003.4111451
GO:0009791post-embryonic development9.17e-021.00e+003.3831252
GO:0001822kidney development9.17e-021.00e+003.3831352
GO:0006368transcription elongation from RNA polymerase II promoter9.17e-021.00e+003.3831852
GO:0016311dephosphorylation9.68e-021.00e+003.3021355
GO:0008584male gonad development1.00e-011.00e+003.2511157
GO:0003729mRNA binding1.00e-011.00e+003.2511457
GO:0042826histone deacetylase binding1.02e-011.00e+003.2251558
GO:0090090negative regulation of canonical Wnt signaling pathway1.03e-011.00e+003.2011559
GO:0005634nucleus1.06e-011.00e+000.58991583246
GO:0006464cellular protein modification process1.07e-011.00e+003.1531461
GO:0030018Z disc1.12e-011.00e+003.0831364
GO:0055085transmembrane transport1.22e-011.00e+001.722213329
GO:0030308negative regulation of cell growth1.22e-011.00e+002.9541370
GO:0051082unfolded protein binding1.22e-011.00e+002.9541570
GO:0044267cellular protein metabolic process1.36e-011.00e+001.624214352
GO:0005819spindle1.38e-011.00e+002.7621680
GO:0005215transporter activity1.41e-011.00e+002.7261582
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.44e-011.00e+002.6911584
GO:0016055Wnt signaling pathway1.49e-011.00e+002.6411687
GO:0005783endoplasmic reticulum1.54e-011.00e+001.510212381
GO:0006461protein complex assembly1.55e-011.00e+002.5761291
GO:0005506iron ion binding1.57e-011.00e+002.5601492
GO:0000209protein polyubiquitination1.57e-011.00e+002.5601692
GO:0006511ubiquitin-dependent protein catabolic process1.57e-011.00e+002.5601692
GO:0006260DNA replication1.60e-011.00e+002.5291994
GO:0006457protein folding1.65e-011.00e+002.4841597
GO:0005516calmodulin binding1.68e-011.00e+002.4541499
GO:0006413translational initiation1.68e-011.00e+002.4541699
GO:0034641cellular nitrogen compound metabolic process1.77e-011.00e+002.36915105
GO:0042803protein homodimerization activity1.85e-011.00e+001.342213428
GO:0042981regulation of apoptotic process1.88e-011.00e+002.27614112
GO:0043005neuron projection1.89e-011.00e+002.26316113
GO:0000287magnesium ion binding1.92e-011.00e+002.23814115
GO:0007049cell cycle1.92e-011.00e+002.23818115
GO:0044281small molecule metabolic process2.00e-011.00e+000.947335844
GO:0000122negative regulation of transcription from RNA polymerase II promoter2.04e-011.00e+001.251229456
GO:0031965nuclear membrane2.15e-011.00e+002.06118130
GO:0044212transcription regulatory region DNA binding2.33e-011.00e+001.924113143
GO:0001701in utero embryonic development2.49e-011.00e+001.81717154
GO:0007067mitotic nuclear division2.64e-011.00e+001.71719165
GO:0016071mRNA metabolic process2.71e-011.00e+001.674110170
GO:0000166nucleotide binding2.79e-011.00e+001.624113176
GO:0006412translation2.82e-011.00e+001.608112178
GO:0004842ubiquitin-protein transferase activity2.83e-011.00e+001.600117179
GO:0016070RNA metabolic process2.95e-011.00e+001.529110188
GO:0005743mitochondrial inner membrane3.07e-011.00e+001.46119197
GO:0015031protein transport3.15e-011.00e+001.418110203
GO:0006281DNA repair3.15e-011.00e+001.418124203
GO:0019899enzyme binding3.24e-011.00e+001.36917210
GO:0003682chromatin binding3.76e-011.00e+001.106115252
GO:0008285negative regulation of cell proliferation4.05e-011.00e+000.970111277
GO:0009986cell surface4.20e-011.00e+000.89915291
GO:0055114oxidation-reduction process4.39e-011.00e+000.81719308
GO:0045892negative regulation of transcription, DNA-templated4.48e-011.00e+000.775117317
GO:0006366transcription from RNA polymerase II promoter4.73e-011.00e+000.670123341
GO:0005509calcium ion binding4.83e-011.00e+000.62819351
GO:0042802identical protein binding4.86e-011.00e+000.616115354
GO:0045893positive regulation of transcription, DNA-templated5.08e-011.00e+000.525121377
GO:0005789endoplasmic reticulum membrane5.17e-011.00e+000.48717387
GO:0046872metal ion binding5.25e-011.00e+000.216224934
GO:0005887integral component of plasma membrane6.65e-011.00e+00-0.08418575
GO:0005730nucleolus6.76e-011.00e+00-0.1662741217
GO:0007165signal transduction6.92e-011.00e+00-0.188124618
GO:0006355regulation of transcription, DNA-templated7.46e-011.00e+00-0.398131715
GO:0070062extracellular vesicular exosome8.31e-011.00e+00-0.5972511641
GO:0003677DNA binding8.41e-011.00e+00-0.804152947
GO:0016021integral component of membrane9.53e-011.00e+00-1.4921191526
GO:0005886plasma membrane9.74e-011.00e+00-1.7171461784