reg-snw-10055

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.386 2.92e-08 1.33e-02 1.12e-02
chia-screen-data-Fav-reg-snw-10055 subnetwork

Genes (18)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
NDUFA4L2 56901 44-2.4772.45921-Yes-
RHOA 387 17-2.4082.64410-YesYes
PHB 5245 82-2.7432.68936-YesYes
[ SAE1 ] 10055 1-1.6192.38676---
VARS 7407 60-2.3662.689124TFYes-
SYMPK 8189 11-1.8902.49251TF--
FBXO22 26263 36-1.7392.459208TF--
NCBP1 4686 41-2.5102.45944-YesYes
EIF2S2 8894 40-2.9992.45922-YesYes
POLR2E 5434 30-2.0372.644201TFYes-
FTSJ1 24140 43-2.4632.68935-YesYes
XPNPEP1 7511 8-1.7792.38676TF--
CCT7 10574 40-2.3352.45938-Yes-
HNRNPU 3192 39-2.8692.64433-Yes-
GPS1 2873 86-3.6212.68936TFYesYes
NOLC1 9221 15-1.9852.503113TF--
DRG2 1819 15-2.5262.49211-Yes-
POLH 5429 36-2.5862.45924-YesYes

Interactions (24)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
NCBP1 4686 FBXO22 26263 pd < reg.ITFP.txt: no annot
HNRNPU 3192 POLR2E 5434 pd < reg.ITFP.txt: no annot
DRG2 1819 SYMPK 8189 pd < reg.ITFP.txt: no annot
SYMPK 8189 SAE1 10055 pd > reg.ITFP.txt: no annot
VARS 7407 SAE1 10055 pd > reg.ITFP.txt: no annot
VARS 7407 FBXO22 26263 pd <> reg.ITFP.txt: no annot
RHOA 387 POLR2E 5434 pd < reg.ITFP.txt: no annot
NOLC1 9221 SAE1 10055 pd > reg.ITFP.txt: no annot
XPNPEP1 7511 SAE1 10055 pd > reg.ITFP.txt: no annot
NOLC1 9221 FTSJ1 24140 pd > reg.ITFP.txt: no annot
VARS 7407 FTSJ1 24140 pd > reg.ITFP.txt: no annot
PHB 5245 VARS 7407 pd < reg.ITFP.txt: no annot
EIF2S2 8894 FBXO22 26263 pd < reg.ITFP.txt: no annot
POLR2E 5434 SAE1 10055 pd > reg.ITFP.txt: no annot
POLR2E 5434 FTSJ1 24140 pd > reg.ITFP.txt: no annot
POLR2E 5434 VARS 7407 pd <> reg.ITFP.txt: no annot
FBXO22 26263 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
PHB 5245 FBXO22 26263 pd < reg.ITFP.txt: no annot
POLH 5429 FBXO22 26263 pd < reg.ITFP.txt: no annot
POLR2E 5434 XPNPEP1 7511 pd <> reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot
CCT7 10574 FBXO22 26263 pd < reg.ITFP.txt: no annot
XPNPEP1 7511 SYMPK 8189 pd <> reg.ITFP.txt: no annot
SAE1 10055 FBXO22 26263 pd < reg.ITFP.txt: no annot

Related GO terms (203)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0005654nucleoplasm6.00e-041.00e+002.116768876
GO:00063707-methylguanosine mRNA capping8.65e-041.00e+005.4992524
GO:0000398mRNA splicing, via spliceosome1.55e-031.00e+003.668315128
GO:0004832valine-tRNA ligase activity1.84e-031.00e+009.083111
GO:0061383trabecula morphogenesis1.84e-031.00e+009.083111
GO:0002128tRNA nucleoside ribose methylation1.84e-031.00e+009.083111
GO:0050434positive regulation of viral transcription1.84e-031.00e+004.9542535
GO:0008175tRNA methyltransferase activity1.84e-031.00e+009.083111
GO:0006438valyl-tRNA aminoacylation1.84e-031.00e+009.083111
GO:0010467gene expression2.29e-031.00e+002.342549535
GO:0008380RNA splicing3.21e-031.00e+003.302321165
GO:0048742regulation of skeletal muscle fiber development3.68e-031.00e+008.083112
GO:0019948SUMO activating enzyme activity3.68e-031.00e+008.083112
GO:0033688regulation of osteoblast proliferation3.68e-031.00e+008.083112
GO:0005846nuclear cap binding complex3.68e-031.00e+008.083112
GO:0002176male germ cell proliferation3.68e-031.00e+008.083112
GO:0031510SUMO activating enzyme complex3.68e-031.00e+008.083112
GO:0019950SMT3-dependent protein catabolic process3.68e-031.00e+008.083112
GO:0006368transcription elongation from RNA polymerase II promoter4.03e-031.00e+004.3832852
GO:0005525GTP binding5.28e-031.00e+003.046312197
GO:0005850eukaryotic translation initiation factor 2 complex5.52e-031.00e+007.499123
GO:0004839ubiquitin activating enzyme activity5.52e-031.00e+007.499113
GO:0070006metalloaminopeptidase activity5.52e-031.00e+007.499113
GO:0005739mitochondrion5.65e-031.00e+002.041532659
GO:0045292mRNA cis splicing, via spliceosome7.35e-031.00e+007.083114
GO:0036089cleavage furrow formation7.35e-031.00e+007.083114
GO:0031442positive regulation of mRNA 3'-end processing7.35e-031.00e+007.083114
GO:0006290pyrimidine dimer repair7.35e-031.00e+007.083124
GO:0007000nucleolus organization7.35e-031.00e+007.083114
GO:0010815bradykinin catabolic process7.35e-031.00e+007.083114
GO:0001649osteoblast differentiation8.01e-031.00e+003.8742574
GO:0070934CRD-mediated mRNA stabilization9.18e-031.00e+006.762125
GO:0038027apolipoprotein A-I-mediated signaling pathway9.18e-031.00e+006.762115
GO:0043931ossification involved in bone maturation9.18e-031.00e+006.762115
GO:0006282regulation of DNA repair9.18e-031.00e+006.762125
GO:2000323negative regulation of glucocorticoid receptor signaling pathway9.18e-031.00e+006.762115
GO:0002161aminoacyl-tRNA editing activity9.18e-031.00e+006.762115
GO:0005829cytosol9.48e-031.00e+001.2808881787
GO:0030529ribonucleoprotein complex9.77e-031.00e+003.7262582
GO:0003723RNA binding9.85e-031.00e+002.720322247
GO:0050847progesterone receptor signaling pathway1.10e-021.00e+006.499126
GO:0002181cytoplasmic translation1.10e-021.00e+006.499116
GO:0001055RNA polymerase II activity1.10e-021.00e+006.499136
GO:0043297apical junction assembly1.10e-021.00e+006.499116
GO:0070937CRD-mediated mRNA stability complex1.10e-021.00e+006.499126
GO:0043008ATP-dependent protein binding1.10e-021.00e+006.499116
GO:0002199zona pellucida receptor complex1.28e-021.00e+006.276147
GO:0000731DNA synthesis involved in DNA repair1.28e-021.00e+006.276117
GO:0006301postreplication repair1.28e-021.00e+006.276127
GO:0000339RNA cap binding1.28e-021.00e+006.276117
GO:0005832chaperonin-containing T-complex1.28e-021.00e+006.276147
GO:0005845mRNA cap binding complex1.47e-021.00e+006.083118
GO:0090307spindle assembly involved in mitosis1.47e-021.00e+006.083128
GO:0006450regulation of translational fidelity1.47e-021.00e+006.083118
GO:0010944negative regulation of transcription by competitive promoter binding1.47e-021.00e+006.083118
GO:0010388cullin deneddylation1.47e-021.00e+006.083148
GO:0043296apical junction complex1.47e-021.00e+006.083118
GO:0010225response to UV-C1.65e-021.00e+005.914129
GO:0006379mRNA cleavage1.65e-021.00e+005.914129
GO:0071354cellular response to interleukin-61.65e-021.00e+005.914119
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process1.65e-021.00e+005.914129
GO:0005736DNA-directed RNA polymerase I complex1.83e-021.00e+005.7621410
GO:0005095GTPase inhibitor activity1.83e-021.00e+005.7621110
GO:0050919negative chemotaxis1.83e-021.00e+005.7621110
GO:0001054RNA polymerase I activity1.83e-021.00e+005.7621410
GO:0035307positive regulation of protein dephosphorylation1.83e-021.00e+005.7621110
GO:0007049cell cycle1.86e-021.00e+003.23828115
GO:0060766negative regulation of androgen receptor signaling pathway2.01e-021.00e+005.6241411
GO:0008334histone mRNA metabolic process2.01e-021.00e+005.6241111
GO:0050772positive regulation of axonogenesis2.37e-021.00e+005.3831213
GO:0050770regulation of axonogenesis2.37e-021.00e+005.3831313
GO:0005666DNA-directed RNA polymerase III complex2.37e-021.00e+005.3831313
GO:0005665DNA-directed RNA polymerase II, core complex2.37e-021.00e+005.3831313
GO:0001056RNA polymerase III activity2.37e-021.00e+005.3831313
GO:0042346positive regulation of NF-kappaB import into nucleus2.37e-021.00e+005.3831113
GO:0044267cellular protein metabolic process2.53e-021.00e+002.209314352
GO:0006386termination of RNA polymerase III transcription2.55e-021.00e+005.2761314
GO:0006385transcription elongation from RNA polymerase III promoter2.55e-021.00e+005.2761314
GO:0050771negative regulation of axonogenesis2.55e-021.00e+005.2761214
GO:0016575histone deacetylation2.55e-021.00e+005.2761214
GO:0004177aminopeptidase activity2.55e-021.00e+005.2761314
GO:0008135translation factor activity, nucleic acid binding2.73e-021.00e+005.1771415
GO:0000188inactivation of MAPK activity2.73e-021.00e+005.1771115
GO:0007339binding of sperm to zona pellucida2.73e-021.00e+005.1771415
GO:0032467positive regulation of cytokinesis2.91e-021.00e+005.0831116
GO:0017022myosin binding2.91e-021.00e+005.0831216
GO:0003887DNA-directed DNA polymerase activity2.91e-021.00e+005.0831216
GO:0005737cytoplasm3.12e-021.00e+000.89191272633
GO:0005515protein binding3.20e-021.00e+000.659121984124
GO:0003899DNA-directed RNA polymerase activity3.27e-021.00e+004.9141318
GO:0031047gene silencing by RNA3.27e-021.00e+004.9141218
GO:0006378mRNA polyadenylation3.27e-021.00e+004.9141318
GO:0036464cytoplasmic ribonucleoprotein granule3.45e-021.00e+004.8361119
GO:0006913nucleocytoplasmic transport3.63e-021.00e+004.7621220
GO:0071897DNA biosynthetic process3.63e-021.00e+004.7621220
GO:0034660ncRNA metabolic process3.63e-021.00e+004.7621120
GO:0007346regulation of mitotic cell cycle3.80e-021.00e+004.6911221
GO:0016925protein sumoylation3.98e-021.00e+004.6241322
GO:0051084'de novo' posttranslational protein folding3.98e-021.00e+004.6241422
GO:0000387spliceosomal snRNP assembly3.98e-021.00e+004.6241122
GO:0016032viral process4.18e-021.00e+001.927330428
GO:0008180COP9 signalosome4.34e-021.00e+004.4991624
GO:0030145manganese ion binding4.69e-021.00e+004.3831326
GO:0009267cellular response to starvation4.69e-021.00e+004.3831126
GO:0051496positive regulation of stress fiber assembly4.69e-021.00e+004.3831226
GO:0005856cytoskeleton4.70e-021.00e+002.51428190
GO:0006360transcription from RNA polymerase I promoter4.87e-021.00e+004.3291427
GO:0008047enzyme activator activity4.87e-021.00e+004.3291227
GO:0006418tRNA aminoacylation for protein translation5.22e-021.00e+004.2251429
GO:0006383transcription from RNA polymerase III promoter5.22e-021.00e+004.2251629
GO:0006446regulation of translational initiation5.22e-021.00e+004.2251229
GO:0006281DNA repair5.29e-021.00e+002.418224203
GO:0032154cleavage furrow5.39e-021.00e+004.1771330
GO:0044822poly(A) RNA binding5.41e-021.00e+001.441445799
GO:0015030Cajal body5.74e-021.00e+004.0831332
GO:0021762substantia nigra development6.09e-021.00e+003.9961134
GO:0007254JNK cascade6.09e-021.00e+003.9961134
GO:0007266Rho protein signal transduction6.26e-021.00e+003.9541235
GO:0031124mRNA 3'-end processing6.26e-021.00e+003.9541435
GO:0044297cell body6.26e-021.00e+003.9541535
GO:0030334regulation of cell migration6.44e-021.00e+003.9141236
GO:0003743translation initiation factor activity6.61e-021.00e+003.8741837
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process6.78e-021.00e+003.8361438
GO:0006369termination of RNA polymerase II transcription6.78e-021.00e+003.8361538
GO:0006396RNA processing7.13e-021.00e+003.7621440
GO:0006283transcription-coupled nucleotide-excision repair7.13e-021.00e+003.7621640
GO:0003684damaged DNA binding7.30e-021.00e+003.7261141
GO:0005524ATP binding7.53e-021.00e+001.283437892
GO:0006406mRNA export from nucleus7.81e-021.00e+003.6241744
GO:0043085positive regulation of catalytic activity7.98e-021.00e+003.5921245
GO:0032481positive regulation of type I interferon production8.49e-021.00e+003.4991348
GO:0006289nucleotide-excision repair9.34e-021.00e+003.3561653
GO:0045666positive regulation of neuron differentiation9.34e-021.00e+003.3561353
GO:0008584male gonad development1.00e-011.00e+003.2511157
GO:0042826histone deacetylase binding1.02e-011.00e+003.2251558
GO:0071013catalytic step 2 spliceosome1.07e-011.00e+003.1531561
GO:0006464cellular protein modification process1.07e-011.00e+003.1531461
GO:0030018Z disc1.12e-011.00e+003.0831364
GO:0005923tight junction1.12e-011.00e+003.0831264
GO:0006364rRNA processing1.17e-011.00e+003.0171267
GO:0030308negative regulation of cell growth1.22e-011.00e+002.9541370
GO:0051082unfolded protein binding1.22e-011.00e+002.9541570
GO:0030496midbody1.26e-011.00e+002.8941673
GO:0006366transcription from RNA polymerase II promoter1.29e-011.00e+001.670223341
GO:0051056regulation of small GTPase mediated signal transduction1.31e-011.00e+002.8361276
GO:0005938cell cortex1.33e-011.00e+002.8171677
GO:0048015phosphatidylinositol-mediated signaling1.43e-011.00e+002.7081283
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.44e-011.00e+002.6911584
GO:0030027lamellipodium1.50e-011.00e+002.6241388
GO:0030036actin cytoskeleton organization1.54e-011.00e+002.5921490
GO:0000209protein polyubiquitination1.57e-011.00e+002.5601692
GO:0006511ubiquitin-dependent protein catabolic process1.57e-011.00e+002.5601692
GO:0006260DNA replication1.60e-011.00e+002.5291994
GO:0006457protein folding1.65e-011.00e+002.4841597
GO:0006413translational initiation1.68e-011.00e+002.4541699
GO:0005730nucleolus1.78e-011.00e+000.8344741217
GO:0007179transforming growth factor beta receptor signaling pathway1.80e-011.00e+002.34215107
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling1.82e-011.00e+002.32912108
GO:0042981regulation of apoptotic process1.88e-011.00e+002.27614112
GO:0008022protein C-terminus binding1.92e-011.00e+002.23815115
GO:0043687post-translational protein modification1.94e-011.00e+002.22511116
GO:0003924GTPase activity1.98e-011.00e+002.18917119
GO:0006184GTP catabolic process2.15e-011.00e+002.06117130
GO:0005634nucleus2.21e-011.00e+000.41981583246
GO:0030168platelet activation2.31e-011.00e+001.94415141
GO:0044212transcription regulatory region DNA binding2.33e-011.00e+001.924113143
GO:0001701in utero embryonic development2.49e-011.00e+001.81717154
GO:0006367transcription initiation from RNA polymerase II promoter2.59e-011.00e+001.753118161
GO:0005874microtubule2.62e-011.00e+001.735110163
GO:0007067mitotic nuclear division2.64e-011.00e+001.71719165
GO:0016071mRNA metabolic process2.71e-011.00e+001.674110170
GO:0007264small GTPase mediated signal transduction2.77e-011.00e+001.64118174
GO:0006412translation2.82e-011.00e+001.608112178
GO:0004842ubiquitin-protein transferase activity2.83e-011.00e+001.600117179
GO:0016567protein ubiquitination2.95e-011.00e+001.529114188
GO:0016070RNA metabolic process2.95e-011.00e+001.529110188
GO:0005743mitochondrial inner membrane3.07e-011.00e+001.46119197
GO:0048011neurotrophin TRK receptor signaling pathway3.10e-011.00e+001.44718199
GO:0007165signal transduction3.17e-011.00e+000.812224618
GO:0019899enzyme binding3.24e-011.00e+001.36917210
GO:0030054cell junction3.34e-011.00e+001.31515218
GO:0043231intracellular membrane-bounded organelle3.34e-011.00e+001.31518218
GO:0070062extracellular vesicular exosome3.58e-011.00e+000.4034511641
GO:0007411axon guidance3.58e-011.00e+001.19518237
GO:0007155cell adhesion3.66e-011.00e+001.15318244
GO:0016020membrane3.88e-011.00e+000.4313561207
GO:0006508proteolysis3.90e-011.00e+001.039111264
GO:0046982protein heterodimerization activity3.91e-011.00e+001.034111265
GO:0008285negative regulation of cell proliferation4.05e-011.00e+000.970111277
GO:0005925focal adhesion4.10e-011.00e+000.944114282
GO:0009986cell surface4.20e-011.00e+000.89915291
GO:0045892negative regulation of transcription, DNA-templated4.48e-011.00e+000.775117317
GO:0007596blood coagulation4.71e-011.00e+000.678113339
GO:0042802identical protein binding4.86e-011.00e+000.616115354
GO:0045893positive regulation of transcription, DNA-templated5.08e-011.00e+000.525121377
GO:0046872metal ion binding5.25e-011.00e+000.216224934
GO:0003677DNA binding5.33e-011.00e+000.196252947
GO:0042803protein homodimerization activity5.54e-011.00e+000.342113428
GO:0045087innate immune response5.74e-011.00e+000.263112452
GO:0000122negative regulation of transcription from RNA polymerase II promoter5.78e-011.00e+000.251129456
GO:0005886plasma membrane6.65e-011.00e+00-0.1323461784
GO:0005887integral component of plasma membrane6.65e-011.00e+00-0.08418575
GO:0006355regulation of transcription, DNA-templated7.46e-011.00e+00-0.398131715