Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
chia-screen-data-Fav | 2.968 | 5.68e-17 | 8.94e-05 | 1.03e-03 |
Gene Symbol | Entrez Gene ID | Frequency | chia-screen-data-Fav gene score | Best subnetwork score | Degree | Chia-Hits Primary | Chia-Hits Secondary |
---|---|---|---|---|---|---|---|
HCFC1 | 3054 | 40 | -2.925 | 3.449 | 71 | Yes | Yes |
[ CCNC ] | 892 | 1 | -1.726 | 2.968 | 101 | - | - |
MED19 | 219541 | 30 | -2.657 | 3.449 | 115 | Yes | - |
CNOT1 | 23019 | 1 | -2.347 | 2.968 | 90 | Yes | - |
MED28 | 80306 | 16 | -2.404 | 3.216 | 80 | Yes | - |
MED13L | 23389 | 12 | -2.550 | 3.159 | 21 | Yes | - |
YAP1 | 10413 | 94 | -4.256 | 3.538 | 53 | Yes | - |
POU5F1 | 5460 | 133 | -5.148 | 3.538 | 179 | Yes | Yes |
PSMD2 | 5708 | 47 | -4.172 | 3.157 | 386 | Yes | Yes |
EIF2S2 | 8894 | 9 | -2.999 | 2.968 | 81 | Yes | Yes |
LUC7L3 | 51747 | 33 | -3.523 | 3.449 | 18 | Yes | - |
TADA2B | 93624 | 11 | -3.061 | 3.082 | 19 | Yes | - |
EIF2B2 | 8892 | 8 | -2.462 | 2.968 | 95 | Yes | Yes |
MED12 | 9968 | 14 | -2.465 | 3.206 | 65 | Yes | - |
NAP1L4 | 4676 | 4 | -1.947 | 3.119 | 187 | - | - |
SRSF3 | 6428 | 73 | -2.992 | 3.538 | 54 | Yes | - |
DDIT3 | 1649 | 60 | -2.825 | 3.504 | 343 | Yes | Yes |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
EIF2B2 | 8892 | TADA2B | 93624 | pp | -- | int.I2D: BioGrid_Fly, BIND_Fly, FlyLow, IntAct_Fly, MINT_Fly |
CCNC | 892 | EIF2B2 | 8892 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
MED28 | 80306 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct |
YAP1 | 10413 | MED28 | 80306 | pp | -- | int.I2D: MINT; int.Mint: MI:0915(physical association) |
SRSF3 | 6428 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: IntAct |
DDIT3 | 1649 | NAP1L4 | 4676 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
CCNC | 892 | CNOT1 | 23019 | pp | -- | int.I2D: BioGrid_Yeast |
HCFC1 | 3054 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
PSMD2 | 5708 | CNOT1 | 23019 | pp | -- | int.I2D: YeastLow |
CCNC | 892 | MED12 | 9968 | pp | -- | int.I2D: BioGrid |
CCNC | 892 | MED28 | 80306 | pp | -- | int.I2D: BioGrid |
MED12 | 9968 | MED28 | 80306 | pp | -- | int.I2D: BioGrid |
MED12 | 9968 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct |
PSMD2 | 5708 | EIF2B2 | 8892 | pp | -- | int.I2D: IntAct_Yeast |
POU5F1 | 5460 | SRSF3 | 6428 | pp | -- | int.I2D: BioGrid |
HCFC1 | 3054 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: IntAct |
CCNC | 892 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct |
LUC7L3 | 51747 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: IntAct |
CCNC | 892 | NAP1L4 | 4676 | pp | -- | int.I2D: BioGrid_Yeast |
EIF2B2 | 8892 | EIF2S2 | 8894 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh |
MED13L | 23389 | MED28 | 80306 | pp | -- | int.I2D: BioGrid |
MED13L | 23389 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct |
CCNC | 892 | MED13L | 23389 | pp | -- | int.I2D: IntAct_Fly, MINT_Fly |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0016592 | mediator complex | 3.79e-10 | 5.46e-06 | 6.921 | 5 | 10 | 35 |
GO:0010467 | gene expression | 3.44e-07 | 4.97e-03 | 3.343 | 8 | 45 | 669 |
GO:0001104 | RNA polymerase II transcription cofactor activity | 7.26e-06 | 1.05e-01 | 6.269 | 3 | 8 | 33 |
GO:0005654 | nucleoplasm | 1.29e-05 | 1.86e-01 | 2.649 | 8 | 64 | 1082 |
GO:0070461 | SAGA-type complex | 1.30e-05 | 1.88e-01 | 8.407 | 2 | 2 | 5 |
GO:0006366 | transcription from RNA polymerase II promoter | 9.36e-05 | 1.00e+00 | 3.340 | 5 | 30 | 419 |
GO:0042789 | mRNA transcription from RNA polymerase II promoter | 1.01e-04 | 1.00e+00 | 7.028 | 2 | 2 | 13 |
GO:0014003 | oligodendrocyte development | 2.45e-04 | 1.00e+00 | 6.407 | 2 | 5 | 20 |
GO:0006355 | regulation of transcription, DNA-templated | 6.86e-04 | 1.00e+00 | 2.352 | 6 | 43 | 997 |
GO:0005515 | protein binding | 7.59e-04 | 1.00e+00 | 0.979 | 14 | 198 | 6024 |
GO:0044822 | poly(A) RNA binding | 9.31e-04 | 1.00e+00 | 2.269 | 6 | 50 | 1056 |
GO:0044212 | transcription regulatory region DNA binding | 9.36e-04 | 1.00e+00 | 3.921 | 3 | 17 | 168 |
GO:0060795 | cell fate commitment involved in formation of primary germ layer | 1.18e-03 | 1.00e+00 | 9.729 | 1 | 1 | 1 |
GO:2000016 | negative regulation of determination of dorsal identity | 1.18e-03 | 1.00e+00 | 9.729 | 1 | 1 | 1 |
GO:0090308 | regulation of methylation-dependent chromatin silencing | 1.18e-03 | 1.00e+00 | 9.729 | 1 | 1 | 1 |
GO:0090081 | regulation of heart induction by regulation of canonical Wnt signaling pathway | 1.18e-03 | 1.00e+00 | 9.729 | 1 | 1 | 1 |
GO:0060965 | negative regulation of gene silencing by miRNA | 1.18e-03 | 1.00e+00 | 9.729 | 1 | 1 | 1 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 1.22e-03 | 1.00e+00 | 3.790 | 3 | 22 | 184 |
GO:0019827 | stem cell maintenance | 1.37e-03 | 1.00e+00 | 5.174 | 2 | 7 | 47 |
GO:0003743 | translation initiation factor activity | 1.49e-03 | 1.00e+00 | 5.114 | 2 | 7 | 49 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 1.72e-03 | 1.00e+00 | 2.427 | 5 | 41 | 789 |
GO:0060242 | contact inhibition | 2.36e-03 | 1.00e+00 | 8.729 | 1 | 1 | 2 |
GO:0019046 | release from viral latency | 2.36e-03 | 1.00e+00 | 8.729 | 1 | 2 | 2 |
GO:0002176 | male germ cell proliferation | 2.36e-03 | 1.00e+00 | 8.729 | 1 | 1 | 2 |
GO:0009786 | regulation of asymmetric cell division | 2.36e-03 | 1.00e+00 | 8.729 | 1 | 1 | 2 |
GO:0044324 | regulation of transcription involved in anterior/posterior axis specification | 2.36e-03 | 1.00e+00 | 8.729 | 1 | 1 | 2 |
GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | 2.36e-03 | 1.00e+00 | 8.729 | 1 | 1 | 2 |
GO:0003713 | transcription coactivator activity | 2.51e-03 | 1.00e+00 | 3.425 | 3 | 24 | 237 |
GO:0005850 | eukaryotic translation initiation factor 2 complex | 3.53e-03 | 1.00e+00 | 8.144 | 1 | 1 | 3 |
GO:0060913 | cardiac cell fate determination | 3.53e-03 | 1.00e+00 | 8.144 | 1 | 1 | 3 |
GO:0003130 | BMP signaling pathway involved in heart induction | 3.53e-03 | 1.00e+00 | 8.144 | 1 | 1 | 3 |
GO:0090245 | axis elongation involved in somitogenesis | 3.53e-03 | 1.00e+00 | 8.144 | 1 | 1 | 3 |
GO:0014044 | Schwann cell development | 4.71e-03 | 1.00e+00 | 7.729 | 1 | 1 | 4 |
GO:0051716 | cellular response to stimulus | 4.71e-03 | 1.00e+00 | 7.729 | 1 | 4 | 4 |
GO:0051151 | negative regulation of smooth muscle cell differentiation | 4.71e-03 | 1.00e+00 | 7.729 | 1 | 1 | 4 |
GO:0046523 | S-methyl-5-thioribose-1-phosphate isomerase activity | 4.71e-03 | 1.00e+00 | 7.729 | 1 | 3 | 4 |
GO:0001714 | endodermal cell fate specification | 5.88e-03 | 1.00e+00 | 7.407 | 1 | 1 | 5 |
GO:0043620 | regulation of DNA-templated transcription in response to stress | 5.88e-03 | 1.00e+00 | 7.407 | 1 | 1 | 5 |
GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly | 5.88e-03 | 1.00e+00 | 7.407 | 1 | 1 | 5 |
GO:0003682 | chromatin binding | 6.20e-03 | 1.00e+00 | 2.960 | 3 | 19 | 327 |
GO:0005851 | eukaryotic translation initiation factor 2B complex | 7.05e-03 | 1.00e+00 | 7.144 | 1 | 4 | 6 |
GO:0006325 | chromatin organization | 8.33e-03 | 1.00e+00 | 3.846 | 2 | 12 | 118 |
GO:0001955 | blood vessel maturation | 9.39e-03 | 1.00e+00 | 6.729 | 1 | 1 | 8 |
GO:0048387 | negative regulation of retinoic acid receptor signaling pathway | 9.39e-03 | 1.00e+00 | 6.729 | 1 | 2 | 8 |
GO:0070688 | MLL5-L complex | 9.39e-03 | 1.00e+00 | 6.729 | 1 | 1 | 8 |
GO:0043254 | regulation of protein complex assembly | 9.39e-03 | 1.00e+00 | 6.729 | 1 | 1 | 8 |
GO:0006413 | translational initiation | 1.02e-02 | 1.00e+00 | 3.695 | 2 | 7 | 131 |
GO:0043995 | histone acetyltransferase activity (H4-K5 specific) | 1.06e-02 | 1.00e+00 | 6.559 | 1 | 5 | 9 |
GO:0046972 | histone acetyltransferase activity (H4-K16 specific) | 1.06e-02 | 1.00e+00 | 6.559 | 1 | 5 | 9 |
GO:0019509 | L-methionine biosynthetic process from methylthioadenosine | 1.06e-02 | 1.00e+00 | 6.559 | 1 | 3 | 9 |
GO:0048188 | Set1C/COMPASS complex | 1.06e-02 | 1.00e+00 | 6.559 | 1 | 4 | 9 |
GO:0006983 | ER overload response | 1.06e-02 | 1.00e+00 | 6.559 | 1 | 1 | 9 |
GO:0016591 | DNA-directed RNA polymerase II, holoenzyme | 1.06e-02 | 1.00e+00 | 6.559 | 1 | 2 | 9 |
GO:0043996 | histone acetyltransferase activity (H4-K8 specific) | 1.06e-02 | 1.00e+00 | 6.559 | 1 | 5 | 9 |
GO:0035413 | positive regulation of catenin import into nucleus | 1.17e-02 | 1.00e+00 | 6.407 | 1 | 2 | 10 |
GO:0060071 | Wnt signaling pathway, planar cell polarity pathway | 1.17e-02 | 1.00e+00 | 6.407 | 1 | 1 | 10 |
GO:0033147 | negative regulation of intracellular estrogen receptor signaling pathway | 1.17e-02 | 1.00e+00 | 6.407 | 1 | 2 | 10 |
GO:1900153 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | 1.17e-02 | 1.00e+00 | 6.407 | 1 | 2 | 10 |
GO:0042974 | retinoic acid receptor binding | 1.29e-02 | 1.00e+00 | 6.269 | 1 | 1 | 11 |
GO:0004535 | poly(A)-specific ribonuclease activity | 1.29e-02 | 1.00e+00 | 6.269 | 1 | 2 | 11 |
GO:2000036 | regulation of stem cell maintenance | 1.29e-02 | 1.00e+00 | 6.269 | 1 | 1 | 11 |
GO:0045662 | negative regulation of myoblast differentiation | 1.29e-02 | 1.00e+00 | 6.269 | 1 | 3 | 11 |
GO:0060391 | positive regulation of SMAD protein import into nucleus | 1.29e-02 | 1.00e+00 | 6.269 | 1 | 4 | 11 |
GO:0060213 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening | 1.29e-02 | 1.00e+00 | 6.269 | 1 | 2 | 11 |
GO:0006974 | cellular response to DNA damage stimulus | 1.34e-02 | 1.00e+00 | 3.490 | 2 | 7 | 151 |
GO:0005838 | proteasome regulatory particle | 1.41e-02 | 1.00e+00 | 6.144 | 1 | 1 | 12 |
GO:0035198 | miRNA binding | 1.41e-02 | 1.00e+00 | 6.144 | 1 | 1 | 12 |
GO:0071480 | cellular response to gamma radiation | 1.52e-02 | 1.00e+00 | 6.028 | 1 | 1 | 13 |
GO:0030914 | STAGA complex | 1.52e-02 | 1.00e+00 | 6.028 | 1 | 3 | 13 |
GO:0030234 | enzyme regulator activity | 1.52e-02 | 1.00e+00 | 6.028 | 1 | 2 | 13 |
GO:0030518 | intracellular steroid hormone receptor signaling pathway | 1.64e-02 | 1.00e+00 | 5.921 | 1 | 6 | 14 |
GO:0005685 | U1 snRNP | 1.64e-02 | 1.00e+00 | 5.921 | 1 | 1 | 14 |
GO:0044267 | cellular protein metabolic process | 1.70e-02 | 1.00e+00 | 2.425 | 3 | 20 | 474 |
GO:0016607 | nuclear speck | 1.71e-02 | 1.00e+00 | 3.302 | 2 | 12 | 172 |
GO:0043981 | histone H4-K5 acetylation | 1.75e-02 | 1.00e+00 | 5.822 | 1 | 5 | 15 |
GO:0042809 | vitamin D receptor binding | 1.75e-02 | 1.00e+00 | 5.822 | 1 | 6 | 15 |
GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex | 1.75e-02 | 1.00e+00 | 5.822 | 1 | 3 | 15 |
GO:0001824 | blastocyst development | 1.75e-02 | 1.00e+00 | 5.822 | 1 | 2 | 15 |
GO:0043982 | histone H4-K8 acetylation | 1.75e-02 | 1.00e+00 | 5.822 | 1 | 5 | 15 |
GO:0030014 | CCR4-NOT complex | 1.75e-02 | 1.00e+00 | 5.822 | 1 | 1 | 15 |
GO:0006376 | mRNA splice site selection | 1.75e-02 | 1.00e+00 | 5.822 | 1 | 1 | 15 |
GO:0005829 | cytosol | 1.79e-02 | 1.00e+00 | 1.251 | 7 | 86 | 2496 |
GO:0003714 | transcription corepressor activity | 1.82e-02 | 1.00e+00 | 3.253 | 2 | 11 | 178 |
GO:0043274 | phospholipase binding | 1.87e-02 | 1.00e+00 | 5.729 | 1 | 1 | 16 |
GO:0042176 | regulation of protein catabolic process | 1.87e-02 | 1.00e+00 | 5.729 | 1 | 2 | 16 |
GO:0001190 | RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription | 1.87e-02 | 1.00e+00 | 5.729 | 1 | 2 | 16 |
GO:0001829 | trophectodermal cell differentiation | 1.99e-02 | 1.00e+00 | 5.641 | 1 | 2 | 17 |
GO:0022624 | proteasome accessory complex | 1.99e-02 | 1.00e+00 | 5.641 | 1 | 1 | 17 |
GO:0043984 | histone H4-K16 acetylation | 2.22e-02 | 1.00e+00 | 5.481 | 1 | 5 | 19 |
GO:0032757 | positive regulation of interleukin-8 production | 2.33e-02 | 1.00e+00 | 5.407 | 1 | 1 | 20 |
GO:0000123 | histone acetyltransferase complex | 2.45e-02 | 1.00e+00 | 5.336 | 1 | 6 | 21 |
GO:0045787 | positive regulation of cell cycle | 2.56e-02 | 1.00e+00 | 5.269 | 1 | 2 | 22 |
GO:0001205 | RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription | 2.56e-02 | 1.00e+00 | 5.269 | 1 | 4 | 22 |
GO:0030864 | cortical actin cytoskeleton | 2.68e-02 | 1.00e+00 | 5.205 | 1 | 1 | 23 |
GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | 2.68e-02 | 1.00e+00 | 5.205 | 1 | 1 | 23 |
GO:0016071 | mRNA metabolic process | 2.78e-02 | 1.00e+00 | 2.928 | 2 | 8 | 223 |
GO:0008135 | translation factor activity, nucleic acid binding | 2.79e-02 | 1.00e+00 | 5.144 | 1 | 3 | 24 |
GO:0008380 | RNA splicing | 2.89e-02 | 1.00e+00 | 2.896 | 2 | 22 | 228 |
GO:0031047 | gene silencing by RNA | 2.91e-02 | 1.00e+00 | 5.085 | 1 | 2 | 25 |
GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening | 2.91e-02 | 1.00e+00 | 5.085 | 1 | 3 | 25 |
GO:0006412 | translation | 2.94e-02 | 1.00e+00 | 2.883 | 2 | 8 | 230 |
GO:0035329 | hippo signaling | 3.02e-02 | 1.00e+00 | 5.028 | 1 | 5 | 26 |
GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic | 3.02e-02 | 1.00e+00 | 5.028 | 1 | 2 | 26 |
GO:0051209 | release of sequestered calcium ion into cytosol | 3.02e-02 | 1.00e+00 | 5.028 | 1 | 1 | 26 |
GO:0046966 | thyroid hormone receptor binding | 3.02e-02 | 1.00e+00 | 5.028 | 1 | 6 | 26 |
GO:0030331 | estrogen receptor binding | 3.14e-02 | 1.00e+00 | 4.974 | 1 | 2 | 27 |
GO:0071339 | MLL1 complex | 3.14e-02 | 1.00e+00 | 4.974 | 1 | 6 | 27 |
GO:0008134 | transcription factor binding | 3.23e-02 | 1.00e+00 | 2.810 | 2 | 18 | 242 |
GO:0016070 | RNA metabolic process | 3.35e-02 | 1.00e+00 | 2.780 | 2 | 8 | 247 |
GO:0042594 | response to starvation | 3.59e-02 | 1.00e+00 | 4.774 | 1 | 4 | 31 |
GO:1903507 | negative regulation of nucleic acid-templated transcription | 3.71e-02 | 1.00e+00 | 4.729 | 1 | 2 | 32 |
GO:0006357 | regulation of transcription from RNA polymerase II promoter | 3.79e-02 | 1.00e+00 | 2.684 | 2 | 23 | 264 |
GO:0016020 | membrane | 3.99e-02 | 1.00e+00 | 1.335 | 5 | 46 | 1681 |
GO:0042552 | myelination | 4.05e-02 | 1.00e+00 | 4.599 | 1 | 4 | 35 |
GO:0030178 | negative regulation of Wnt signaling pathway | 4.05e-02 | 1.00e+00 | 4.599 | 1 | 4 | 35 |
GO:0006446 | regulation of translational initiation | 4.16e-02 | 1.00e+00 | 4.559 | 1 | 4 | 36 |
GO:0001541 | ovarian follicle development | 4.28e-02 | 1.00e+00 | 4.519 | 1 | 2 | 37 |
GO:0009408 | response to heat | 4.61e-02 | 1.00e+00 | 4.407 | 1 | 6 | 40 |
GO:0035019 | somatic stem cell maintenance | 4.61e-02 | 1.00e+00 | 4.407 | 1 | 6 | 40 |
GO:0003700 | sequence-specific DNA binding transcription factor activity | 4.64e-02 | 1.00e+00 | 1.864 | 3 | 39 | 699 |
GO:0030521 | androgen receptor signaling pathway | 4.73e-02 | 1.00e+00 | 4.371 | 1 | 5 | 41 |
GO:0031124 | mRNA 3'-end processing | 4.84e-02 | 1.00e+00 | 4.336 | 1 | 2 | 42 |
GO:0003677 | DNA binding | 4.95e-02 | 1.00e+00 | 1.478 | 4 | 49 | 1218 |
GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity | 4.95e-02 | 1.00e+00 | 4.302 | 1 | 7 | 43 |
GO:0003712 | transcription cofactor activity | 5.06e-02 | 1.00e+00 | 4.269 | 1 | 8 | 44 |
GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity | 5.18e-02 | 1.00e+00 | 4.237 | 1 | 2 | 45 |
GO:0043434 | response to peptide hormone | 5.18e-02 | 1.00e+00 | 4.237 | 1 | 5 | 45 |
GO:0006369 | termination of RNA polymerase II transcription | 5.18e-02 | 1.00e+00 | 4.237 | 1 | 2 | 45 |
GO:0043525 | positive regulation of neuron apoptotic process | 5.29e-02 | 1.00e+00 | 4.205 | 1 | 4 | 46 |
GO:0005778 | peroxisomal membrane | 5.40e-02 | 1.00e+00 | 4.174 | 1 | 1 | 47 |
GO:0005634 | nucleus | 5.52e-02 | 1.00e+00 | 0.744 | 9 | 159 | 4559 |
GO:0006521 | regulation of cellular amino acid metabolic process | 5.74e-02 | 1.00e+00 | 4.085 | 1 | 1 | 50 |
GO:0006986 | response to unfolded protein | 5.74e-02 | 1.00e+00 | 4.085 | 1 | 4 | 50 |
GO:0034976 | response to endoplasmic reticulum stress | 5.85e-02 | 1.00e+00 | 4.056 | 1 | 2 | 51 |
GO:0045454 | cell redox homeostasis | 5.85e-02 | 1.00e+00 | 4.056 | 1 | 1 | 51 |
GO:0009611 | response to wounding | 5.96e-02 | 1.00e+00 | 4.028 | 1 | 5 | 52 |
GO:0003723 | RNA binding | 6.03e-02 | 1.00e+00 | 2.311 | 2 | 18 | 342 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 6.07e-02 | 1.00e+00 | 4.001 | 1 | 5 | 53 |
GO:0000288 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | 6.07e-02 | 1.00e+00 | 4.001 | 1 | 4 | 53 |
GO:0043565 | sequence-specific DNA binding | 6.16e-02 | 1.00e+00 | 2.294 | 2 | 11 | 346 |
GO:0000932 | cytoplasmic mRNA processing body | 6.18e-02 | 1.00e+00 | 3.974 | 1 | 4 | 54 |
GO:0000502 | proteasome complex | 6.62e-02 | 1.00e+00 | 3.871 | 1 | 3 | 58 |
GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity | 6.73e-02 | 1.00e+00 | 3.846 | 1 | 6 | 59 |
GO:0008013 | beta-catenin binding | 6.85e-02 | 1.00e+00 | 3.822 | 1 | 9 | 60 |
GO:0006406 | mRNA export from nucleus | 6.96e-02 | 1.00e+00 | 3.798 | 1 | 4 | 61 |
GO:0006987 | activation of signaling protein activity involved in unfolded protein response | 6.96e-02 | 1.00e+00 | 3.798 | 1 | 2 | 61 |
GO:0006417 | regulation of translation | 7.07e-02 | 1.00e+00 | 3.774 | 1 | 2 | 62 |
GO:0009749 | response to glucose | 7.29e-02 | 1.00e+00 | 3.729 | 1 | 7 | 64 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 7.29e-02 | 1.00e+00 | 3.729 | 1 | 1 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 7.40e-02 | 1.00e+00 | 3.706 | 1 | 2 | 65 |
GO:0010468 | regulation of gene expression | 7.72e-02 | 1.00e+00 | 3.641 | 1 | 2 | 68 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 7.94e-02 | 1.00e+00 | 3.599 | 1 | 2 | 70 |
GO:0005085 | guanyl-nucleotide exchange factor activity | 8.05e-02 | 1.00e+00 | 3.579 | 1 | 5 | 71 |
GO:0006334 | nucleosome assembly | 8.16e-02 | 1.00e+00 | 3.559 | 1 | 3 | 72 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 8.16e-02 | 1.00e+00 | 3.559 | 1 | 1 | 72 |
GO:0003729 | mRNA binding | 8.16e-02 | 1.00e+00 | 3.559 | 1 | 4 | 72 |
GO:0006351 | transcription, DNA-templated | 8.31e-02 | 1.00e+00 | 1.231 | 4 | 57 | 1446 |
GO:0001843 | neural tube closure | 8.38e-02 | 1.00e+00 | 3.519 | 1 | 2 | 74 |
GO:0000981 | sequence-specific DNA binding RNA polymerase II transcription factor activity | 8.38e-02 | 1.00e+00 | 3.519 | 1 | 4 | 74 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 8.38e-02 | 1.00e+00 | 3.519 | 1 | 2 | 74 |
GO:0008584 | male gonad development | 8.49e-02 | 1.00e+00 | 3.500 | 1 | 3 | 75 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 8.49e-02 | 1.00e+00 | 3.500 | 1 | 1 | 75 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 8.49e-02 | 1.00e+00 | 3.500 | 1 | 1 | 75 |
GO:0060070 | canonical Wnt signaling pathway | 8.49e-02 | 1.00e+00 | 3.500 | 1 | 4 | 75 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 8.92e-02 | 1.00e+00 | 3.425 | 1 | 2 | 79 |
GO:0030968 | endoplasmic reticulum unfolded protein response | 8.92e-02 | 1.00e+00 | 3.425 | 1 | 2 | 79 |
GO:0009653 | anatomical structure morphogenesis | 9.35e-02 | 1.00e+00 | 3.354 | 1 | 2 | 83 |
GO:0090090 | negative regulation of canonical Wnt signaling pathway | 9.67e-02 | 1.00e+00 | 3.302 | 1 | 8 | 86 |
GO:0050821 | protein stabilization | 9.89e-02 | 1.00e+00 | 3.269 | 1 | 3 | 88 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 1.03e-01 | 1.00e+00 | 3.205 | 1 | 1 | 92 |
GO:0005770 | late endosome | 1.04e-01 | 1.00e+00 | 3.189 | 1 | 2 | 93 |
GO:0051082 | unfolded protein binding | 1.04e-01 | 1.00e+00 | 3.189 | 1 | 7 | 93 |
GO:0045893 | positive regulation of transcription, DNA-templated | 1.07e-01 | 1.00e+00 | 1.828 | 2 | 24 | 478 |
GO:0007417 | central nervous system development | 1.07e-01 | 1.00e+00 | 3.144 | 1 | 5 | 96 |
GO:0000209 | protein polyubiquitination | 1.28e-01 | 1.00e+00 | 2.871 | 1 | 3 | 116 |
GO:0007219 | Notch signaling pathway | 1.32e-01 | 1.00e+00 | 2.822 | 1 | 5 | 120 |
GO:0007050 | cell cycle arrest | 1.37e-01 | 1.00e+00 | 2.774 | 1 | 5 | 124 |
GO:0007179 | transforming growth factor beta receptor signaling pathway | 1.41e-01 | 1.00e+00 | 2.729 | 1 | 11 | 128 |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 1.44e-01 | 1.00e+00 | 1.574 | 2 | 37 | 570 |
GO:0016055 | Wnt signaling pathway | 1.51e-01 | 1.00e+00 | 2.620 | 1 | 4 | 138 |
GO:0007507 | heart development | 1.52e-01 | 1.00e+00 | 2.610 | 1 | 7 | 139 |
GO:0010628 | positive regulation of gene expression | 1.59e-01 | 1.00e+00 | 2.539 | 1 | 7 | 146 |
GO:0000082 | G1/S transition of mitotic cell cycle | 1.62e-01 | 1.00e+00 | 2.509 | 1 | 3 | 149 |
GO:0042981 | regulation of apoptotic process | 1.63e-01 | 1.00e+00 | 2.500 | 1 | 4 | 150 |
GO:0008022 | protein C-terminus binding | 1.74e-01 | 1.00e+00 | 2.398 | 1 | 8 | 161 |
GO:0000398 | mRNA splicing, via spliceosome | 1.77e-01 | 1.00e+00 | 2.371 | 1 | 15 | 164 |
GO:0034641 | cellular nitrogen compound metabolic process | 1.84e-01 | 1.00e+00 | 2.311 | 1 | 2 | 171 |
GO:0007049 | cell cycle | 1.87e-01 | 1.00e+00 | 2.286 | 1 | 6 | 174 |
GO:0005667 | transcription factor complex | 1.88e-01 | 1.00e+00 | 2.277 | 1 | 17 | 175 |
GO:0031625 | ubiquitin protein ligase binding | 1.90e-01 | 1.00e+00 | 2.253 | 1 | 5 | 178 |
GO:0019904 | protein domain specific binding | 1.91e-01 | 1.00e+00 | 2.245 | 1 | 8 | 179 |
GO:0043547 | positive regulation of GTPase activity | 1.92e-01 | 1.00e+00 | 2.237 | 1 | 9 | 180 |
GO:0004872 | receptor activity | 2.01e-01 | 1.00e+00 | 2.166 | 1 | 8 | 189 |
GO:0001701 | in utero embryonic development | 2.12e-01 | 1.00e+00 | 2.078 | 1 | 8 | 201 |
GO:0043025 | neuronal cell body | 2.53e-01 | 1.00e+00 | 1.792 | 1 | 9 | 245 |
GO:0000166 | nucleotide binding | 2.65e-01 | 1.00e+00 | 1.712 | 1 | 13 | 259 |
GO:0005737 | cytoplasm | 2.70e-01 | 1.00e+00 | 0.434 | 6 | 124 | 3767 |
GO:0003779 | actin binding | 2.71e-01 | 1.00e+00 | 1.673 | 1 | 10 | 266 |
GO:0005730 | nucleolus | 3.04e-01 | 1.00e+00 | 0.633 | 3 | 66 | 1641 |
GO:0005525 | GTP binding | 3.09e-01 | 1.00e+00 | 1.452 | 1 | 12 | 310 |
GO:0019901 | protein kinase binding | 3.15e-01 | 1.00e+00 | 1.420 | 1 | 18 | 317 |
GO:0008283 | cell proliferation | 3.24e-01 | 1.00e+00 | 1.371 | 1 | 14 | 328 |
GO:0005925 | focal adhesion | 3.54e-01 | 1.00e+00 | 1.213 | 1 | 9 | 366 |
GO:0046982 | protein heterodimerization activity | 3.65e-01 | 1.00e+00 | 1.159 | 1 | 8 | 380 |
GO:0000278 | mitotic cell cycle | 3.73e-01 | 1.00e+00 | 1.118 | 1 | 15 | 391 |
GO:0045892 | negative regulation of transcription, DNA-templated | 3.90e-01 | 1.00e+00 | 1.039 | 1 | 24 | 413 |
GO:0043066 | negative regulation of apoptotic process | 3.98e-01 | 1.00e+00 | 1.001 | 1 | 16 | 424 |
GO:0042802 | identical protein binding | 4.40e-01 | 1.00e+00 | 0.810 | 1 | 19 | 484 |
GO:0016032 | viral process | 4.74e-01 | 1.00e+00 | 0.668 | 1 | 26 | 534 |
GO:0006915 | apoptotic process | 4.87e-01 | 1.00e+00 | 0.612 | 1 | 12 | 555 |
GO:0005615 | extracellular space | 6.89e-01 | 1.00e+00 | -0.174 | 1 | 20 | 957 |
GO:0008270 | zinc ion binding | 7.04e-01 | 1.00e+00 | -0.233 | 1 | 27 | 997 |
GO:0005739 | mitochondrion | 7.05e-01 | 1.00e+00 | -0.234 | 1 | 23 | 998 |
GO:0044281 | small molecule metabolic process | 7.75e-01 | 1.00e+00 | -0.513 | 1 | 20 | 1211 |
GO:0005524 | ATP binding | 7.99e-01 | 1.00e+00 | -0.613 | 1 | 31 | 1298 |
GO:0046872 | metal ion binding | 8.01e-01 | 1.00e+00 | -0.623 | 1 | 29 | 1307 |
GO:0070062 | extracellular vesicular exosome | 9.55e-01 | 1.00e+00 | -1.500 | 1 | 57 | 2400 |
GO:0005886 | plasma membrane | 9.65e-01 | 1.00e+00 | -1.606 | 1 | 49 | 2582 |