Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
chia-screen-data-Fav | 2.861 | 8.61e-16 | 3.52e-04 | 2.70e-03 |
Gene Symbol | Entrez Gene ID | Frequency | chia-screen-data-Fav gene score | Best subnetwork score | Degree | Chia-Hits Primary | Chia-Hits Secondary |
---|---|---|---|---|---|---|---|
TADA3 | 10474 | 2 | -1.911 | 3.082 | 49 | - | - |
EP300 | 2033 | 22 | -2.274 | 3.120 | 415 | Yes | Yes |
PSMD2 | 5708 | 47 | -4.172 | 3.157 | 386 | Yes | Yes |
MAGEH1 | 28986 | 2 | -2.307 | 3.082 | 10 | Yes | - |
TADA2B | 93624 | 11 | -3.061 | 3.082 | 19 | Yes | - |
HES6 | 55502 | 8 | -2.557 | 3.120 | 11 | Yes | Yes |
EIF2B2 | 8892 | 8 | -2.462 | 2.968 | 95 | Yes | Yes |
YAP1 | 10413 | 94 | -4.256 | 3.538 | 53 | Yes | - |
TCL1A | 8115 | 8 | -2.457 | 3.120 | 11 | Yes | Yes |
[ ADPGK ] | 83440 | 1 | -1.188 | 2.861 | 4 | - | - |
POU5F1 | 5460 | 133 | -5.148 | 3.538 | 179 | Yes | Yes |
HNRNPU | 3192 | 76 | -2.869 | 3.538 | 139 | Yes | - |
YY1 | 7528 | 24 | -2.572 | 3.120 | 114 | Yes | Yes |
DDIT3 | 1649 | 60 | -2.825 | 3.504 | 343 | Yes | Yes |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
EP300 | 2033 | HNRNPU | 3192 | pp | -- | int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vitro, in vivo |
EIF2B2 | 8892 | TADA2B | 93624 | pp | -- | int.I2D: BioGrid_Fly, BIND_Fly, FlyLow, IntAct_Fly, MINT_Fly |
HNRNPU | 3192 | YAP1 | 10413 | pp | -- | int.I2D: HPRD; int.HPRD: in vitro, in vivo |
TADA3 | 10474 | MAGEH1 | 28986 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BIND, MINT, HPRD, IntAct; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid |
EP300 | 2033 | TADA3 | 10474 | pp | -- | int.I2D: BioGrid, HPRD, BCI; int.Transfac: -; int.Ravasi: -; int.HPRD: in vivo, yeast 2-hybrid |
EP300 | 2033 | YY1 | 7528 | pp | -- | int.I2D: BioGrid, BCI, HPRD; int.Transfac: -; int.Ravasi: -; int.HPRD: in vivo; int.DIP: MI:0218(physical interaction) |
TADA3 | 10474 | TADA2B | 93624 | pp | -- | int.I2D: BioGrid_Fly, BIND_Fly, FlyHigh, IntAct_Fly, MINT_Fly |
PSMD2 | 5708 | EIF2B2 | 8892 | pp | -- | int.I2D: IntAct_Yeast |
EP300 | 2033 | TCL1A | 8115 | pp | -- | int.I2D: INNATEDB |
HNRNPU | 3192 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
EP300 | 2033 | YAP1 | 10413 | pp | -- | int.I2D: BioGrid |
TADA3 | 10474 | ADPGK | 83440 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: HPRD, MINT, StelzlLow, IntAct; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid |
DDIT3 | 1649 | HNRNPU | 3192 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
EP300 | 2033 | HES6 | 55502 | pp | -- | int.I2D: IntAct |
DDIT3 | 1649 | EP300 | 2033 | pp | -- | int.Intact: MI:0915(physical association) |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0090043 | regulation of tubulin deacetylation | 8.75e-07 | 1.26e-02 | 10.009 | 2 | 2 | 2 |
GO:0044212 | transcription regulatory region DNA binding | 1.62e-05 | 2.34e-01 | 4.616 | 4 | 17 | 168 |
GO:0005667 | transcription factor complex | 1.91e-05 | 2.75e-01 | 4.558 | 4 | 17 | 175 |
GO:0003700 | sequence-specific DNA binding transcription factor activity | 2.73e-05 | 3.93e-01 | 3.145 | 6 | 39 | 699 |
GO:0003677 | DNA binding | 6.08e-05 | 8.76e-01 | 2.566 | 7 | 49 | 1218 |
GO:0003713 | transcription coactivator activity | 6.25e-05 | 9.02e-01 | 4.120 | 4 | 24 | 237 |
GO:0042789 | mRNA transcription from RNA polymerase II promoter | 6.78e-05 | 9.78e-01 | 7.308 | 2 | 2 | 13 |
GO:0008134 | transcription factor binding | 6.78e-05 | 9.78e-01 | 4.090 | 4 | 18 | 242 |
GO:0030914 | STAGA complex | 6.78e-05 | 9.78e-01 | 7.308 | 2 | 3 | 13 |
GO:0006325 | chromatin organization | 1.82e-04 | 1.00e+00 | 4.711 | 3 | 12 | 118 |
GO:0006355 | regulation of transcription, DNA-templated | 1.99e-04 | 1.00e+00 | 2.632 | 6 | 43 | 997 |
GO:0005654 | nucleoplasm | 3.12e-04 | 1.00e+00 | 2.514 | 6 | 64 | 1082 |
GO:0006974 | cellular response to DNA damage stimulus | 3.76e-04 | 1.00e+00 | 4.355 | 3 | 7 | 151 |
GO:0003714 | transcription corepressor activity | 6.09e-04 | 1.00e+00 | 4.118 | 3 | 11 | 178 |
GO:0004402 | histone acetyltransferase activity | 7.72e-04 | 1.00e+00 | 5.582 | 2 | 6 | 43 |
GO:0043966 | histone H3 acetylation | 8.46e-04 | 1.00e+00 | 5.517 | 2 | 5 | 45 |
GO:2000016 | negative regulation of determination of dorsal identity | 9.71e-04 | 1.00e+00 | 10.009 | 1 | 1 | 1 |
GO:1901985 | positive regulation of protein acetylation | 9.71e-04 | 1.00e+00 | 10.009 | 1 | 1 | 1 |
GO:0043843 | ADP-specific glucokinase activity | 9.71e-04 | 1.00e+00 | 10.009 | 1 | 1 | 1 |
GO:0043969 | histone H2B acetylation | 9.71e-04 | 1.00e+00 | 10.009 | 1 | 1 | 1 |
GO:0090308 | regulation of methylation-dependent chromatin silencing | 9.71e-04 | 1.00e+00 | 10.009 | 1 | 1 | 1 |
GO:0090081 | regulation of heart induction by regulation of canonical Wnt signaling pathway | 9.71e-04 | 1.00e+00 | 10.009 | 1 | 1 | 1 |
GO:0060965 | negative regulation of gene silencing by miRNA | 9.71e-04 | 1.00e+00 | 10.009 | 1 | 1 | 1 |
GO:0060795 | cell fate commitment involved in formation of primary germ layer | 9.71e-04 | 1.00e+00 | 10.009 | 1 | 1 | 1 |
GO:0060177 | regulation of angiotensin metabolic process | 9.71e-04 | 1.00e+00 | 10.009 | 1 | 1 | 1 |
GO:2000629 | negative regulation of miRNA metabolic process | 9.71e-04 | 1.00e+00 | 10.009 | 1 | 1 | 1 |
GO:0006357 | regulation of transcription from RNA polymerase II promoter | 1.90e-03 | 1.00e+00 | 3.549 | 3 | 23 | 264 |
GO:0060242 | contact inhibition | 1.94e-03 | 1.00e+00 | 9.009 | 1 | 1 | 2 |
GO:0006403 | RNA localization | 1.94e-03 | 1.00e+00 | 9.009 | 1 | 1 | 2 |
GO:0009786 | regulation of asymmetric cell division | 1.94e-03 | 1.00e+00 | 9.009 | 1 | 1 | 2 |
GO:0071389 | cellular response to mineralocorticoid stimulus | 1.94e-03 | 1.00e+00 | 9.009 | 1 | 1 | 2 |
GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | 1.94e-03 | 1.00e+00 | 9.009 | 1 | 1 | 2 |
GO:0034696 | response to prostaglandin F | 1.94e-03 | 1.00e+00 | 9.009 | 1 | 1 | 2 |
GO:0014737 | positive regulation of muscle atrophy | 1.94e-03 | 1.00e+00 | 9.009 | 1 | 1 | 2 |
GO:0035984 | cellular response to trichostatin A | 1.94e-03 | 1.00e+00 | 9.009 | 1 | 1 | 2 |
GO:0044324 | regulation of transcription involved in anterior/posterior axis specification | 1.94e-03 | 1.00e+00 | 9.009 | 1 | 1 | 2 |
GO:0018076 | N-terminal peptidyl-lysine acetylation | 2.91e-03 | 1.00e+00 | 8.424 | 1 | 1 | 3 |
GO:0060913 | cardiac cell fate determination | 2.91e-03 | 1.00e+00 | 8.424 | 1 | 1 | 3 |
GO:0010560 | positive regulation of glycoprotein biosynthetic process | 2.91e-03 | 1.00e+00 | 8.424 | 1 | 1 | 3 |
GO:0003130 | BMP signaling pathway involved in heart induction | 2.91e-03 | 1.00e+00 | 8.424 | 1 | 1 | 3 |
GO:0010467 | gene expression | 3.16e-03 | 1.00e+00 | 2.623 | 4 | 45 | 669 |
GO:0051716 | cellular response to stimulus | 3.88e-03 | 1.00e+00 | 8.009 | 1 | 4 | 4 |
GO:0097157 | pre-mRNA intronic binding | 3.88e-03 | 1.00e+00 | 8.009 | 1 | 1 | 4 |
GO:0018393 | internal peptidyl-lysine acetylation | 3.88e-03 | 1.00e+00 | 8.009 | 1 | 1 | 4 |
GO:0046523 | S-methyl-5-thioribose-1-phosphate isomerase activity | 3.88e-03 | 1.00e+00 | 8.009 | 1 | 3 | 4 |
GO:0031063 | regulation of histone deacetylation | 3.88e-03 | 1.00e+00 | 8.009 | 1 | 1 | 4 |
GO:0070461 | SAGA-type complex | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 2 | 5 |
GO:0001714 | endodermal cell fate specification | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 1 | 5 |
GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 1 | 5 |
GO:0043620 | regulation of DNA-templated transcription in response to stress | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 1 | 5 |
GO:0070934 | CRD-mediated mRNA stabilization | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 2 | 5 |
GO:0065004 | protein-DNA complex assembly | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 1 | 5 |
GO:0060298 | positive regulation of sarcomere organization | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 1 | 5 |
GO:0032025 | response to cobalt ion | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 1 | 5 |
GO:0070937 | CRD-mediated mRNA stability complex | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 3 | 6 |
GO:0005851 | eukaryotic translation initiation factor 2B complex | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 4 | 6 |
GO:0006475 | internal protein amino acid acetylation | 6.78e-03 | 1.00e+00 | 7.201 | 1 | 1 | 7 |
GO:0001955 | blood vessel maturation | 7.74e-03 | 1.00e+00 | 7.009 | 1 | 1 | 8 |
GO:0035259 | glucocorticoid receptor binding | 8.70e-03 | 1.00e+00 | 6.839 | 1 | 1 | 9 |
GO:0045793 | positive regulation of cell size | 8.70e-03 | 1.00e+00 | 6.839 | 1 | 2 | 9 |
GO:0060765 | regulation of androgen receptor signaling pathway | 8.70e-03 | 1.00e+00 | 6.839 | 1 | 1 | 9 |
GO:0010225 | response to UV-C | 8.70e-03 | 1.00e+00 | 6.839 | 1 | 2 | 9 |
GO:0019509 | L-methionine biosynthetic process from methylthioadenosine | 8.70e-03 | 1.00e+00 | 6.839 | 1 | 3 | 9 |
GO:0006983 | ER overload response | 8.70e-03 | 1.00e+00 | 6.839 | 1 | 1 | 9 |
GO:0000400 | four-way junction DNA binding | 8.70e-03 | 1.00e+00 | 6.839 | 1 | 1 | 9 |
GO:0006351 | transcription, DNA-templated | 9.29e-03 | 1.00e+00 | 1.833 | 5 | 57 | 1446 |
GO:0035413 | positive regulation of catenin import into nucleus | 9.67e-03 | 1.00e+00 | 6.687 | 1 | 2 | 10 |
GO:0016407 | acetyltransferase activity | 9.67e-03 | 1.00e+00 | 6.687 | 1 | 2 | 10 |
GO:0045662 | negative regulation of myoblast differentiation | 1.06e-02 | 1.00e+00 | 6.549 | 1 | 3 | 11 |
GO:0045120 | pronucleus | 1.06e-02 | 1.00e+00 | 6.549 | 1 | 2 | 11 |
GO:0043923 | positive regulation by host of viral transcription | 1.06e-02 | 1.00e+00 | 6.549 | 1 | 1 | 11 |
GO:0033160 | positive regulation of protein import into nucleus, translocation | 1.06e-02 | 1.00e+00 | 6.549 | 1 | 3 | 11 |
GO:0042975 | peroxisome proliferator activated receptor binding | 1.06e-02 | 1.00e+00 | 6.549 | 1 | 1 | 11 |
GO:0060391 | positive regulation of SMAD protein import into nucleus | 1.06e-02 | 1.00e+00 | 6.549 | 1 | 4 | 11 |
GO:0005838 | proteasome regulatory particle | 1.16e-02 | 1.00e+00 | 6.424 | 1 | 1 | 12 |
GO:0035198 | miRNA binding | 1.16e-02 | 1.00e+00 | 6.424 | 1 | 1 | 12 |
GO:0071480 | cellular response to gamma radiation | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 1 | 13 |
GO:0016746 | transferase activity, transferring acyl groups | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 1 | 13 |
GO:0051019 | mitogen-activated protein kinase binding | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 2 | 13 |
GO:0030234 | enzyme regulator activity | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 2 | 13 |
GO:0033276 | transcription factor TFTC complex | 1.35e-02 | 1.00e+00 | 6.201 | 1 | 4 | 14 |
GO:0031011 | Ino80 complex | 1.35e-02 | 1.00e+00 | 6.201 | 1 | 6 | 14 |
GO:0070542 | response to fatty acid | 1.35e-02 | 1.00e+00 | 6.201 | 1 | 1 | 14 |
GO:0032993 | protein-DNA complex | 1.35e-02 | 1.00e+00 | 6.201 | 1 | 2 | 14 |
GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex | 1.45e-02 | 1.00e+00 | 6.102 | 1 | 3 | 15 |
GO:0001824 | blastocyst development | 1.45e-02 | 1.00e+00 | 6.102 | 1 | 2 | 15 |
GO:1990090 | cellular response to nerve growth factor stimulus | 1.45e-02 | 1.00e+00 | 6.102 | 1 | 1 | 15 |
GO:0006915 | apoptotic process | 1.50e-02 | 1.00e+00 | 2.477 | 3 | 12 | 555 |
GO:0042176 | regulation of protein catabolic process | 1.54e-02 | 1.00e+00 | 6.009 | 1 | 2 | 16 |
GO:0051276 | chromosome organization | 1.54e-02 | 1.00e+00 | 6.009 | 1 | 2 | 16 |
GO:0048593 | camera-type eye morphogenesis | 1.54e-02 | 1.00e+00 | 6.009 | 1 | 1 | 16 |
GO:0022624 | proteasome accessory complex | 1.64e-02 | 1.00e+00 | 5.921 | 1 | 1 | 17 |
GO:0016922 | ligand-dependent nuclear receptor binding | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 1 | 18 |
GO:0030520 | intracellular estrogen receptor signaling pathway | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 4 | 18 |
GO:0045773 | positive regulation of axon extension | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 1 | 18 |
GO:0033613 | activating transcription factor binding | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 3 | 18 |
GO:0035257 | nuclear hormone receptor binding | 1.83e-02 | 1.00e+00 | 5.761 | 1 | 1 | 19 |
GO:0071549 | cellular response to dexamethasone stimulus | 1.92e-02 | 1.00e+00 | 5.687 | 1 | 3 | 20 |
GO:0010942 | positive regulation of cell death | 1.92e-02 | 1.00e+00 | 5.687 | 1 | 1 | 20 |
GO:0032757 | positive regulation of interleukin-8 production | 1.92e-02 | 1.00e+00 | 5.687 | 1 | 1 | 20 |
GO:0001932 | regulation of protein phosphorylation | 1.92e-02 | 1.00e+00 | 5.687 | 1 | 1 | 20 |
GO:0014003 | oligodendrocyte development | 1.92e-02 | 1.00e+00 | 5.687 | 1 | 5 | 20 |
GO:0032967 | positive regulation of collagen biosynthetic process | 2.02e-02 | 1.00e+00 | 5.616 | 1 | 3 | 21 |
GO:0045862 | positive regulation of proteolysis | 2.02e-02 | 1.00e+00 | 5.616 | 1 | 2 | 21 |
GO:0000123 | histone acetyltransferase complex | 2.02e-02 | 1.00e+00 | 5.616 | 1 | 6 | 21 |
GO:0007399 | nervous system development | 2.05e-02 | 1.00e+00 | 3.157 | 2 | 6 | 231 |
GO:0003823 | antigen binding | 2.12e-02 | 1.00e+00 | 5.549 | 1 | 2 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 2.12e-02 | 1.00e+00 | 5.549 | 1 | 2 | 22 |
GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | 2.21e-02 | 1.00e+00 | 5.485 | 1 | 1 | 23 |
GO:0043388 | positive regulation of DNA binding | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 2 | 24 |
GO:0043425 | bHLH transcription factor binding | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 1 | 24 |
GO:0031519 | PcG protein complex | 2.40e-02 | 1.00e+00 | 5.365 | 1 | 1 | 25 |
GO:0051059 | NF-kappaB binding | 2.40e-02 | 1.00e+00 | 5.365 | 1 | 3 | 25 |
GO:0005515 | protein binding | 2.44e-02 | 1.00e+00 | 0.774 | 10 | 198 | 6024 |
GO:0035329 | hippo signaling | 2.50e-02 | 1.00e+00 | 5.308 | 1 | 5 | 26 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 2.50e-02 | 1.00e+00 | 5.308 | 1 | 1 | 26 |
GO:0051209 | release of sequestered calcium ion into cytosol | 2.50e-02 | 1.00e+00 | 5.308 | 1 | 1 | 26 |
GO:0048565 | digestive tract development | 2.50e-02 | 1.00e+00 | 5.308 | 1 | 2 | 26 |
GO:0034612 | response to tumor necrosis factor | 2.59e-02 | 1.00e+00 | 5.254 | 1 | 2 | 27 |
GO:0043967 | histone H4 acetylation | 2.59e-02 | 1.00e+00 | 5.254 | 1 | 1 | 27 |
GO:0050714 | positive regulation of protein secretion | 2.69e-02 | 1.00e+00 | 5.201 | 1 | 3 | 28 |
GO:0072686 | mitotic spindle | 2.78e-02 | 1.00e+00 | 5.151 | 1 | 3 | 29 |
GO:0031647 | regulation of protein stability | 2.87e-02 | 1.00e+00 | 5.102 | 1 | 4 | 30 |
GO:0034644 | cellular response to UV | 2.87e-02 | 1.00e+00 | 5.102 | 1 | 1 | 30 |
GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | 2.87e-02 | 1.00e+00 | 5.102 | 1 | 1 | 30 |
GO:0042594 | response to starvation | 2.97e-02 | 1.00e+00 | 5.055 | 1 | 4 | 31 |
GO:0043491 | protein kinase B signaling | 3.06e-02 | 1.00e+00 | 5.009 | 1 | 2 | 32 |
GO:1903507 | negative regulation of nucleic acid-templated transcription | 3.06e-02 | 1.00e+00 | 5.009 | 1 | 2 | 32 |
GO:0001756 | somitogenesis | 3.16e-02 | 1.00e+00 | 4.964 | 1 | 1 | 33 |
GO:0071333 | cellular response to glucose stimulus | 3.16e-02 | 1.00e+00 | 4.964 | 1 | 1 | 33 |
GO:0030154 | cell differentiation | 3.35e-02 | 1.00e+00 | 2.775 | 2 | 5 | 301 |
GO:0042552 | myelination | 3.35e-02 | 1.00e+00 | 4.879 | 1 | 4 | 35 |
GO:0001102 | RNA polymerase II activating transcription factor binding | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 1 | 36 |
GO:0006446 | regulation of translational initiation | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 4 | 36 |
GO:0001541 | ovarian follicle development | 3.53e-02 | 1.00e+00 | 4.799 | 1 | 2 | 37 |
GO:0031490 | chromatin DNA binding | 3.63e-02 | 1.00e+00 | 4.761 | 1 | 2 | 38 |
GO:0006096 | glycolytic process | 3.63e-02 | 1.00e+00 | 4.761 | 1 | 3 | 38 |
GO:0032092 | positive regulation of protein binding | 3.63e-02 | 1.00e+00 | 4.761 | 1 | 2 | 38 |
GO:0050681 | androgen receptor binding | 3.63e-02 | 1.00e+00 | 4.761 | 1 | 1 | 38 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 3.78e-02 | 1.00e+00 | 1.970 | 3 | 41 | 789 |
GO:0046332 | SMAD binding | 3.82e-02 | 1.00e+00 | 4.687 | 1 | 2 | 40 |
GO:0071320 | cellular response to cAMP | 3.82e-02 | 1.00e+00 | 4.687 | 1 | 1 | 40 |
GO:0009408 | response to heat | 3.82e-02 | 1.00e+00 | 4.687 | 1 | 6 | 40 |
GO:0035019 | somatic stem cell maintenance | 3.82e-02 | 1.00e+00 | 4.687 | 1 | 6 | 40 |
GO:0007519 | skeletal muscle tissue development | 3.82e-02 | 1.00e+00 | 4.687 | 1 | 2 | 40 |
GO:0003682 | chromatin binding | 3.90e-02 | 1.00e+00 | 2.656 | 2 | 19 | 327 |
GO:0070301 | cellular response to hydrogen peroxide | 3.91e-02 | 1.00e+00 | 4.651 | 1 | 2 | 41 |
GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity | 4.10e-02 | 1.00e+00 | 4.582 | 1 | 7 | 43 |
GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding | 4.19e-02 | 1.00e+00 | 4.549 | 1 | 4 | 44 |
GO:0003712 | transcription cofactor activity | 4.19e-02 | 1.00e+00 | 4.549 | 1 | 8 | 44 |
GO:0045727 | positive regulation of translation | 4.19e-02 | 1.00e+00 | 4.549 | 1 | 2 | 44 |
GO:0003723 | RNA binding | 4.23e-02 | 1.00e+00 | 2.591 | 2 | 18 | 342 |
GO:0005634 | nucleus | 4.26e-02 | 1.00e+00 | 0.854 | 8 | 159 | 4559 |
GO:0001047 | core promoter binding | 4.28e-02 | 1.00e+00 | 4.517 | 1 | 5 | 45 |
GO:0043434 | response to peptide hormone | 4.28e-02 | 1.00e+00 | 4.517 | 1 | 5 | 45 |
GO:0043565 | sequence-specific DNA binding | 4.32e-02 | 1.00e+00 | 2.574 | 2 | 11 | 346 |
GO:0043525 | positive regulation of neuron apoptotic process | 4.38e-02 | 1.00e+00 | 4.485 | 1 | 4 | 46 |
GO:0019827 | stem cell maintenance | 4.47e-02 | 1.00e+00 | 4.454 | 1 | 7 | 47 |
GO:0003743 | translation initiation factor activity | 4.65e-02 | 1.00e+00 | 4.394 | 1 | 7 | 49 |
GO:0035690 | cellular response to drug | 4.65e-02 | 1.00e+00 | 4.394 | 1 | 3 | 49 |
GO:0006521 | regulation of cellular amino acid metabolic process | 4.75e-02 | 1.00e+00 | 4.365 | 1 | 1 | 50 |
GO:0006986 | response to unfolded protein | 4.75e-02 | 1.00e+00 | 4.365 | 1 | 4 | 50 |
GO:0034976 | response to endoplasmic reticulum stress | 4.84e-02 | 1.00e+00 | 4.336 | 1 | 2 | 51 |
GO:0045454 | cell redox homeostasis | 4.84e-02 | 1.00e+00 | 4.336 | 1 | 1 | 51 |
GO:0009611 | response to wounding | 4.93e-02 | 1.00e+00 | 4.308 | 1 | 5 | 52 |
GO:0007623 | circadian rhythm | 5.03e-02 | 1.00e+00 | 4.281 | 1 | 1 | 53 |
GO:0051592 | response to calcium ion | 5.21e-02 | 1.00e+00 | 4.227 | 1 | 1 | 55 |
GO:0002039 | p53 binding | 5.21e-02 | 1.00e+00 | 4.227 | 1 | 4 | 55 |
GO:0071300 | cellular response to retinoic acid | 5.21e-02 | 1.00e+00 | 4.227 | 1 | 1 | 55 |
GO:0000724 | double-strand break repair via homologous recombination | 5.21e-02 | 1.00e+00 | 4.227 | 1 | 2 | 55 |
GO:0043627 | response to estrogen | 5.30e-02 | 1.00e+00 | 4.201 | 1 | 5 | 56 |
GO:0000278 | mitotic cell cycle | 5.38e-02 | 1.00e+00 | 2.398 | 2 | 15 | 391 |
GO:0000502 | proteasome complex | 5.49e-02 | 1.00e+00 | 4.151 | 1 | 3 | 58 |
GO:0006396 | RNA processing | 5.58e-02 | 1.00e+00 | 4.126 | 1 | 5 | 59 |
GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity | 5.58e-02 | 1.00e+00 | 4.126 | 1 | 6 | 59 |
GO:0001078 | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription | 5.58e-02 | 1.00e+00 | 4.126 | 1 | 5 | 59 |
GO:0008013 | beta-catenin binding | 5.67e-02 | 1.00e+00 | 4.102 | 1 | 9 | 60 |
GO:0006987 | activation of signaling protein activity involved in unfolded protein response | 5.76e-02 | 1.00e+00 | 4.078 | 1 | 2 | 61 |
GO:0032481 | positive regulation of type I interferon production | 5.76e-02 | 1.00e+00 | 4.078 | 1 | 6 | 61 |
GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | 5.95e-02 | 1.00e+00 | 4.031 | 1 | 4 | 63 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 6.04e-02 | 1.00e+00 | 4.009 | 1 | 1 | 64 |
GO:0009749 | response to glucose | 6.04e-02 | 1.00e+00 | 4.009 | 1 | 7 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 6.13e-02 | 1.00e+00 | 3.986 | 1 | 2 | 65 |
GO:0010468 | regulation of gene expression | 6.40e-02 | 1.00e+00 | 3.921 | 1 | 2 | 68 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 6.59e-02 | 1.00e+00 | 3.879 | 1 | 2 | 70 |
GO:0005085 | guanyl-nucleotide exchange factor activity | 6.68e-02 | 1.00e+00 | 3.859 | 1 | 5 | 71 |
GO:0008270 | zinc ion binding | 6.76e-02 | 1.00e+00 | 1.632 | 3 | 27 | 997 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 6.77e-02 | 1.00e+00 | 3.839 | 1 | 1 | 72 |
GO:0030324 | lung development | 6.77e-02 | 1.00e+00 | 3.839 | 1 | 1 | 72 |
GO:0000785 | chromatin | 6.86e-02 | 1.00e+00 | 3.819 | 1 | 6 | 73 |
GO:0000981 | sequence-specific DNA binding RNA polymerase II transcription factor activity | 6.95e-02 | 1.00e+00 | 3.799 | 1 | 4 | 74 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 6.95e-02 | 1.00e+00 | 3.799 | 1 | 2 | 74 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 7.04e-02 | 1.00e+00 | 3.780 | 1 | 1 | 75 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 7.04e-02 | 1.00e+00 | 3.780 | 1 | 1 | 75 |
GO:0001889 | liver development | 7.22e-02 | 1.00e+00 | 3.742 | 1 | 3 | 77 |
GO:0071013 | catalytic step 2 spliceosome | 7.31e-02 | 1.00e+00 | 3.723 | 1 | 7 | 78 |
GO:0030968 | endoplasmic reticulum unfolded protein response | 7.40e-02 | 1.00e+00 | 3.705 | 1 | 2 | 79 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 7.40e-02 | 1.00e+00 | 3.705 | 1 | 2 | 79 |
GO:0044267 | cellular protein metabolic process | 7.56e-02 | 1.00e+00 | 2.120 | 2 | 20 | 474 |
GO:0045893 | positive regulation of transcription, DNA-templated | 7.67e-02 | 1.00e+00 | 2.108 | 2 | 24 | 478 |
GO:0009653 | anatomical structure morphogenesis | 7.77e-02 | 1.00e+00 | 3.634 | 1 | 2 | 83 |
GO:0009952 | anterior/posterior pattern specification | 7.77e-02 | 1.00e+00 | 3.634 | 1 | 4 | 83 |
GO:0005829 | cytosol | 7.88e-02 | 1.00e+00 | 1.045 | 5 | 86 | 2496 |
GO:0009887 | organ morphogenesis | 8.04e-02 | 1.00e+00 | 3.582 | 1 | 5 | 86 |
GO:0090090 | negative regulation of canonical Wnt signaling pathway | 8.04e-02 | 1.00e+00 | 3.582 | 1 | 8 | 86 |
GO:0045471 | response to ethanol | 8.04e-02 | 1.00e+00 | 3.582 | 1 | 3 | 86 |
GO:0016310 | phosphorylation | 8.39e-02 | 1.00e+00 | 3.517 | 1 | 2 | 90 |
GO:0016363 | nuclear matrix | 8.48e-02 | 1.00e+00 | 3.501 | 1 | 6 | 91 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 8.57e-02 | 1.00e+00 | 3.485 | 1 | 1 | 92 |
GO:0001649 | osteoblast differentiation | 8.57e-02 | 1.00e+00 | 3.485 | 1 | 5 | 92 |
GO:0071456 | cellular response to hypoxia | 8.57e-02 | 1.00e+00 | 3.485 | 1 | 3 | 92 |
GO:0051091 | positive regulation of sequence-specific DNA binding transcription factor activity | 8.57e-02 | 1.00e+00 | 3.485 | 1 | 7 | 92 |
GO:0005770 | late endosome | 8.66e-02 | 1.00e+00 | 3.470 | 1 | 2 | 93 |
GO:0007417 | central nervous system development | 8.93e-02 | 1.00e+00 | 3.424 | 1 | 5 | 96 |
GO:0051726 | regulation of cell cycle | 9.02e-02 | 1.00e+00 | 3.409 | 1 | 5 | 97 |
GO:0016032 | viral process | 9.28e-02 | 1.00e+00 | 1.948 | 2 | 26 | 534 |
GO:0001934 | positive regulation of protein phosphorylation | 9.64e-02 | 1.00e+00 | 3.308 | 1 | 5 | 104 |
GO:0005938 | cell cortex | 9.64e-02 | 1.00e+00 | 3.308 | 1 | 5 | 104 |
GO:0030529 | ribonucleoprotein complex | 1.03e-01 | 1.00e+00 | 3.201 | 1 | 5 | 112 |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 1.04e-01 | 1.00e+00 | 1.854 | 2 | 37 | 570 |
GO:0000209 | protein polyubiquitination | 1.07e-01 | 1.00e+00 | 3.151 | 1 | 3 | 116 |
GO:0046983 | protein dimerization activity | 1.09e-01 | 1.00e+00 | 3.126 | 1 | 5 | 118 |
GO:0007219 | Notch signaling pathway | 1.10e-01 | 1.00e+00 | 3.102 | 1 | 5 | 120 |
GO:0007050 | cell cycle arrest | 1.14e-01 | 1.00e+00 | 3.055 | 1 | 5 | 124 |
GO:0006413 | translational initiation | 1.20e-01 | 1.00e+00 | 2.975 | 1 | 7 | 131 |
GO:0000086 | G2/M transition of mitotic cell cycle | 1.24e-01 | 1.00e+00 | 2.921 | 1 | 4 | 136 |
GO:0016055 | Wnt signaling pathway | 1.26e-01 | 1.00e+00 | 2.900 | 1 | 4 | 138 |
GO:0007507 | heart development | 1.27e-01 | 1.00e+00 | 2.890 | 1 | 7 | 139 |
GO:0010628 | positive regulation of gene expression | 1.33e-01 | 1.00e+00 | 2.819 | 1 | 7 | 146 |
GO:0001666 | response to hypoxia | 1.35e-01 | 1.00e+00 | 2.790 | 1 | 7 | 149 |
GO:0000082 | G1/S transition of mitotic cell cycle | 1.35e-01 | 1.00e+00 | 2.790 | 1 | 3 | 149 |
GO:0042981 | regulation of apoptotic process | 1.36e-01 | 1.00e+00 | 2.780 | 1 | 4 | 150 |
GO:0000398 | mRNA splicing, via spliceosome | 1.48e-01 | 1.00e+00 | 2.651 | 1 | 15 | 164 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.49e-01 | 1.00e+00 | 2.642 | 1 | 12 | 165 |
GO:0034641 | cellular nitrogen compound metabolic process | 1.54e-01 | 1.00e+00 | 2.591 | 1 | 2 | 171 |
GO:0019904 | protein domain specific binding | 1.60e-01 | 1.00e+00 | 2.525 | 1 | 8 | 179 |
GO:0031625 | ubiquitin protein ligase binding | 1.60e-01 | 1.00e+00 | 2.533 | 1 | 5 | 178 |
GO:0043547 | positive regulation of GTPase activity | 1.61e-01 | 1.00e+00 | 2.517 | 1 | 9 | 180 |
GO:0032403 | protein complex binding | 1.64e-01 | 1.00e+00 | 2.493 | 1 | 6 | 183 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 1.65e-01 | 1.00e+00 | 2.485 | 1 | 22 | 184 |
GO:0005622 | intracellular | 1.83e-01 | 1.00e+00 | 2.315 | 1 | 6 | 207 |
GO:0016071 | mRNA metabolic process | 1.96e-01 | 1.00e+00 | 2.208 | 1 | 8 | 223 |
GO:0007067 | mitotic nuclear division | 1.99e-01 | 1.00e+00 | 2.182 | 1 | 6 | 227 |
GO:0008380 | RNA splicing | 2.00e-01 | 1.00e+00 | 2.176 | 1 | 22 | 228 |
GO:0006412 | translation | 2.02e-01 | 1.00e+00 | 2.163 | 1 | 8 | 230 |
GO:0016070 | RNA metabolic process | 2.15e-01 | 1.00e+00 | 2.060 | 1 | 8 | 247 |
GO:0016020 | membrane | 2.18e-01 | 1.00e+00 | 0.879 | 3 | 46 | 1681 |
GO:0007283 | spermatogenesis | 2.26e-01 | 1.00e+00 | 1.975 | 1 | 3 | 262 |
GO:0005525 | GTP binding | 2.62e-01 | 1.00e+00 | 1.733 | 1 | 12 | 310 |
GO:0007275 | multicellular organismal development | 2.67e-01 | 1.00e+00 | 1.705 | 1 | 7 | 316 |
GO:0044822 | poly(A) RNA binding | 2.74e-01 | 1.00e+00 | 0.964 | 2 | 50 | 1056 |
GO:0008283 | cell proliferation | 2.75e-01 | 1.00e+00 | 1.651 | 1 | 14 | 328 |
GO:0005737 | cytoplasm | 2.92e-01 | 1.00e+00 | 0.451 | 5 | 124 | 3767 |
GO:0046982 | protein heterodimerization activity | 3.12e-01 | 1.00e+00 | 1.439 | 1 | 8 | 380 |
GO:0009986 | cell surface | 3.27e-01 | 1.00e+00 | 1.358 | 1 | 9 | 402 |
GO:0045892 | negative regulation of transcription, DNA-templated | 3.34e-01 | 1.00e+00 | 1.319 | 1 | 24 | 413 |
GO:0006366 | transcription from RNA polymerase II promoter | 3.38e-01 | 1.00e+00 | 1.298 | 1 | 30 | 419 |
GO:0043066 | negative regulation of apoptotic process | 3.42e-01 | 1.00e+00 | 1.281 | 1 | 16 | 424 |
GO:0005524 | ATP binding | 3.63e-01 | 1.00e+00 | 0.667 | 2 | 31 | 1298 |
GO:0005783 | endoplasmic reticulum | 4.23e-01 | 1.00e+00 | 0.890 | 1 | 13 | 556 |
GO:0045087 | innate immune response | 4.46e-01 | 1.00e+00 | 0.790 | 1 | 15 | 596 |
GO:0005730 | nucleolus | 4.84e-01 | 1.00e+00 | 0.328 | 2 | 66 | 1641 |
GO:0005576 | extracellular region | 6.12e-01 | 1.00e+00 | 0.129 | 1 | 13 | 942 |
GO:0044281 | small molecule metabolic process | 7.07e-01 | 1.00e+00 | -0.233 | 1 | 20 | 1211 |
GO:0046872 | metal ion binding | 7.36e-01 | 1.00e+00 | -0.343 | 1 | 29 | 1307 |
GO:0070062 | extracellular vesicular exosome | 9.22e-01 | 1.00e+00 | -1.220 | 1 | 57 | 2400 |