Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
chia-screen-data-Fav | 2.988 | 3.41e-17 | 6.87e-05 | 8.50e-04 |
Gene Symbol | Entrez Gene ID | Frequency | chia-screen-data-Fav gene score | Best subnetwork score | Degree | Chia-Hits Primary | Chia-Hits Secondary |
---|---|---|---|---|---|---|---|
EP300 | 2033 | 22 | -2.274 | 3.120 | 415 | Yes | Yes |
[ ZNF232 ] | 7775 | 1 | -1.481 | 2.988 | 4 | - | - |
MCRS1 | 10445 | 14 | -2.660 | 3.079 | 63 | Yes | Yes |
YAP1 | 10413 | 94 | -4.256 | 3.538 | 53 | Yes | - |
INO80E | 283899 | 10 | -2.663 | 3.079 | 20 | Yes | - |
NFRKB | 4798 | 48 | -3.129 | 3.108 | 23 | Yes | Yes |
POU5F1 | 5460 | 133 | -5.148 | 3.538 | 179 | Yes | Yes |
YY1 | 7528 | 24 | -2.572 | 3.120 | 114 | Yes | Yes |
HNRNPU | 3192 | 76 | -2.869 | 3.538 | 139 | Yes | - |
DDIT3 | 1649 | 60 | -2.825 | 3.504 | 343 | Yes | Yes |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
MCRS1 | 10445 | INO80E | 283899 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct |
YY1 | 7528 | ZNF232 | 7775 | pp | -- | int.I2D: BioGrid; int.Ravasi: - |
NFRKB | 4798 | INO80E | 283899 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid |
NFRKB | 4798 | MCRS1 | 10445 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid |
EP300 | 2033 | YY1 | 7528 | pp | -- | int.I2D: BioGrid, BCI, HPRD; int.Transfac: -; int.Ravasi: -; int.HPRD: in vivo; int.DIP: MI:0218(physical interaction) |
DDIT3 | 1649 | HNRNPU | 3192 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
NFRKB | 4798 | YY1 | 7528 | pp | -- | int.I2D: BioGrid |
HNRNPU | 3192 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
DDIT3 | 1649 | EP300 | 2033 | pp | -- | int.Intact: MI:0915(physical association) |
YY1 | 7528 | INO80E | 283899 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid |
EP300 | 2033 | HNRNPU | 3192 | pp | -- | int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vitro, in vivo |
NFRKB | 4798 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
HNRNPU | 3192 | YAP1 | 10413 | pp | -- | int.I2D: HPRD; int.HPRD: in vitro, in vivo |
EP300 | 2033 | YAP1 | 10413 | pp | -- | int.I2D: BioGrid |
YY1 | 7528 | MCRS1 | 10445 | pp | -- | int.I2D: BioGrid |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0031011 | Ino80 complex | 1.16e-10 | 1.68e-06 | 8.687 | 4 | 6 | 14 |
GO:0006355 | regulation of transcription, DNA-templated | 2.02e-08 | 2.91e-04 | 3.533 | 8 | 43 | 997 |
GO:0003677 | DNA binding | 2.88e-06 | 4.15e-02 | 3.051 | 7 | 49 | 1218 |
GO:0044212 | transcription regulatory region DNA binding | 3.53e-06 | 5.09e-02 | 5.102 | 4 | 17 | 168 |
GO:0005634 | nucleus | 9.89e-06 | 1.43e-01 | 1.662 | 10 | 159 | 4559 |
GO:0006310 | DNA recombination | 1.03e-05 | 1.48e-01 | 6.057 | 3 | 7 | 65 |
GO:0005654 | nucleoplasm | 2.84e-05 | 4.09e-01 | 3.000 | 6 | 64 | 1082 |
GO:0042789 | mRNA transcription from RNA polymerase II promoter | 3.36e-05 | 4.85e-01 | 7.794 | 2 | 2 | 13 |
GO:0003700 | sequence-specific DNA binding transcription factor activity | 5.42e-05 | 7.82e-01 | 3.367 | 5 | 39 | 699 |
GO:0000123 | histone acetyltransferase complex | 9.02e-05 | 1.00e+00 | 7.102 | 2 | 6 | 21 |
GO:0006974 | cellular response to DNA damage stimulus | 1.28e-04 | 1.00e+00 | 4.841 | 3 | 7 | 151 |
GO:0005667 | transcription factor complex | 1.98e-04 | 1.00e+00 | 4.628 | 3 | 17 | 175 |
GO:0003714 | transcription corepressor activity | 2.08e-04 | 1.00e+00 | 4.603 | 3 | 11 | 178 |
GO:0003713 | transcription coactivator activity | 4.83e-04 | 1.00e+00 | 4.190 | 3 | 24 | 237 |
GO:0008134 | transcription factor binding | 5.13e-04 | 1.00e+00 | 4.160 | 3 | 18 | 242 |
GO:0006281 | DNA repair | 6.40e-04 | 1.00e+00 | 4.051 | 3 | 14 | 261 |
GO:0060795 | cell fate commitment involved in formation of primary germ layer | 6.93e-04 | 1.00e+00 | 10.494 | 1 | 1 | 1 |
GO:0060177 | regulation of angiotensin metabolic process | 6.93e-04 | 1.00e+00 | 10.494 | 1 | 1 | 1 |
GO:2000016 | negative regulation of determination of dorsal identity | 6.93e-04 | 1.00e+00 | 10.494 | 1 | 1 | 1 |
GO:1901985 | positive regulation of protein acetylation | 6.93e-04 | 1.00e+00 | 10.494 | 1 | 1 | 1 |
GO:0043969 | histone H2B acetylation | 6.93e-04 | 1.00e+00 | 10.494 | 1 | 1 | 1 |
GO:2000629 | negative regulation of miRNA metabolic process | 6.93e-04 | 1.00e+00 | 10.494 | 1 | 1 | 1 |
GO:0090308 | regulation of methylation-dependent chromatin silencing | 6.93e-04 | 1.00e+00 | 10.494 | 1 | 1 | 1 |
GO:0090081 | regulation of heart induction by regulation of canonical Wnt signaling pathway | 6.93e-04 | 1.00e+00 | 10.494 | 1 | 1 | 1 |
GO:0060965 | negative regulation of gene silencing by miRNA | 6.93e-04 | 1.00e+00 | 10.494 | 1 | 1 | 1 |
GO:0034696 | response to prostaglandin F | 1.39e-03 | 1.00e+00 | 9.494 | 1 | 1 | 2 |
GO:0060242 | contact inhibition | 1.39e-03 | 1.00e+00 | 9.494 | 1 | 1 | 2 |
GO:0014737 | positive regulation of muscle atrophy | 1.39e-03 | 1.00e+00 | 9.494 | 1 | 1 | 2 |
GO:0006403 | RNA localization | 1.39e-03 | 1.00e+00 | 9.494 | 1 | 1 | 2 |
GO:0009786 | regulation of asymmetric cell division | 1.39e-03 | 1.00e+00 | 9.494 | 1 | 1 | 2 |
GO:0090043 | regulation of tubulin deacetylation | 1.39e-03 | 1.00e+00 | 9.494 | 1 | 2 | 2 |
GO:0035984 | cellular response to trichostatin A | 1.39e-03 | 1.00e+00 | 9.494 | 1 | 1 | 2 |
GO:0071389 | cellular response to mineralocorticoid stimulus | 1.39e-03 | 1.00e+00 | 9.494 | 1 | 1 | 2 |
GO:0044324 | regulation of transcription involved in anterior/posterior axis specification | 1.39e-03 | 1.00e+00 | 9.494 | 1 | 1 | 2 |
GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | 1.39e-03 | 1.00e+00 | 9.494 | 1 | 1 | 2 |
GO:0006351 | transcription, DNA-templated | 1.65e-03 | 1.00e+00 | 2.318 | 5 | 57 | 1446 |
GO:0018076 | N-terminal peptidyl-lysine acetylation | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 3 |
GO:0060913 | cardiac cell fate determination | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 3 |
GO:0003130 | BMP signaling pathway involved in heart induction | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 3 |
GO:0010560 | positive regulation of glycoprotein biosynthetic process | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 3 |
GO:0005515 | protein binding | 2.41e-03 | 1.00e+00 | 1.108 | 9 | 198 | 6024 |
GO:0097157 | pre-mRNA intronic binding | 2.77e-03 | 1.00e+00 | 8.494 | 1 | 1 | 4 |
GO:0018393 | internal peptidyl-lysine acetylation | 2.77e-03 | 1.00e+00 | 8.494 | 1 | 1 | 4 |
GO:0006325 | chromatin organization | 2.86e-03 | 1.00e+00 | 4.612 | 2 | 12 | 118 |
GO:0001714 | endodermal cell fate specification | 3.46e-03 | 1.00e+00 | 8.172 | 1 | 1 | 5 |
GO:0065004 | protein-DNA complex assembly | 3.46e-03 | 1.00e+00 | 8.172 | 1 | 1 | 5 |
GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor | 3.46e-03 | 1.00e+00 | 8.172 | 1 | 1 | 5 |
GO:0043620 | regulation of DNA-templated transcription in response to stress | 3.46e-03 | 1.00e+00 | 8.172 | 1 | 1 | 5 |
GO:0070934 | CRD-mediated mRNA stabilization | 3.46e-03 | 1.00e+00 | 8.172 | 1 | 2 | 5 |
GO:0060298 | positive regulation of sarcomere organization | 3.46e-03 | 1.00e+00 | 8.172 | 1 | 1 | 5 |
GO:0032025 | response to cobalt ion | 3.46e-03 | 1.00e+00 | 8.172 | 1 | 1 | 5 |
GO:0070937 | CRD-mediated mRNA stability complex | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 3 | 6 |
GO:0006475 | internal protein amino acid acetylation | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 1 | 7 |
GO:0001955 | blood vessel maturation | 5.53e-03 | 1.00e+00 | 7.494 | 1 | 1 | 8 |
GO:0043995 | histone acetyltransferase activity (H4-K5 specific) | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 5 | 9 |
GO:0046972 | histone acetyltransferase activity (H4-K16 specific) | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 5 | 9 |
GO:0060765 | regulation of androgen receptor signaling pathway | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 1 | 9 |
GO:0010225 | response to UV-C | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 2 | 9 |
GO:0006983 | ER overload response | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 1 | 9 |
GO:0035259 | glucocorticoid receptor binding | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 1 | 9 |
GO:0045793 | positive regulation of cell size | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 2 | 9 |
GO:0000400 | four-way junction DNA binding | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 1 | 9 |
GO:0043996 | histone acetyltransferase activity (H4-K8 specific) | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 5 | 9 |
GO:0035413 | positive regulation of catenin import into nucleus | 6.91e-03 | 1.00e+00 | 7.172 | 1 | 2 | 10 |
GO:0016407 | acetyltransferase activity | 6.91e-03 | 1.00e+00 | 7.172 | 1 | 2 | 10 |
GO:0043923 | positive regulation by host of viral transcription | 7.60e-03 | 1.00e+00 | 7.035 | 1 | 1 | 11 |
GO:0033160 | positive regulation of protein import into nucleus, translocation | 7.60e-03 | 1.00e+00 | 7.035 | 1 | 3 | 11 |
GO:0045662 | negative regulation of myoblast differentiation | 7.60e-03 | 1.00e+00 | 7.035 | 1 | 3 | 11 |
GO:0042975 | peroxisome proliferator activated receptor binding | 7.60e-03 | 1.00e+00 | 7.035 | 1 | 1 | 11 |
GO:0060391 | positive regulation of SMAD protein import into nucleus | 7.60e-03 | 1.00e+00 | 7.035 | 1 | 4 | 11 |
GO:0035198 | miRNA binding | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 12 |
GO:0071480 | cellular response to gamma radiation | 8.98e-03 | 1.00e+00 | 6.794 | 1 | 1 | 13 |
GO:0051019 | mitogen-activated protein kinase binding | 8.98e-03 | 1.00e+00 | 6.794 | 1 | 2 | 13 |
GO:0016746 | transferase activity, transferring acyl groups | 8.98e-03 | 1.00e+00 | 6.794 | 1 | 1 | 13 |
GO:0070542 | response to fatty acid | 9.67e-03 | 1.00e+00 | 6.687 | 1 | 1 | 14 |
GO:0032993 | protein-DNA complex | 9.67e-03 | 1.00e+00 | 6.687 | 1 | 2 | 14 |
GO:0043981 | histone H4-K5 acetylation | 1.04e-02 | 1.00e+00 | 6.587 | 1 | 5 | 15 |
GO:0001824 | blastocyst development | 1.04e-02 | 1.00e+00 | 6.587 | 1 | 2 | 15 |
GO:0043982 | histone H4-K8 acetylation | 1.04e-02 | 1.00e+00 | 6.587 | 1 | 5 | 15 |
GO:1990090 | cellular response to nerve growth factor stimulus | 1.04e-02 | 1.00e+00 | 6.587 | 1 | 1 | 15 |
GO:0051276 | chromosome organization | 1.10e-02 | 1.00e+00 | 6.494 | 1 | 2 | 16 |
GO:0048593 | camera-type eye morphogenesis | 1.10e-02 | 1.00e+00 | 6.494 | 1 | 1 | 16 |
GO:0045773 | positive regulation of axon extension | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 1 | 18 |
GO:0033613 | activating transcription factor binding | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 3 | 18 |
GO:0043984 | histone H4-K16 acetylation | 1.31e-02 | 1.00e+00 | 6.246 | 1 | 5 | 19 |
GO:0035257 | nuclear hormone receptor binding | 1.31e-02 | 1.00e+00 | 6.246 | 1 | 1 | 19 |
GO:0071549 | cellular response to dexamethasone stimulus | 1.38e-02 | 1.00e+00 | 6.172 | 1 | 3 | 20 |
GO:0010942 | positive regulation of cell death | 1.38e-02 | 1.00e+00 | 6.172 | 1 | 1 | 20 |
GO:0032757 | positive regulation of interleukin-8 production | 1.38e-02 | 1.00e+00 | 6.172 | 1 | 1 | 20 |
GO:0032967 | positive regulation of collagen biosynthetic process | 1.45e-02 | 1.00e+00 | 6.102 | 1 | 3 | 21 |
GO:0045862 | positive regulation of proteolysis | 1.45e-02 | 1.00e+00 | 6.102 | 1 | 2 | 21 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 1.47e-02 | 1.00e+00 | 2.455 | 3 | 41 | 789 |
GO:0003823 | antigen binding | 1.52e-02 | 1.00e+00 | 6.035 | 1 | 2 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 1.52e-02 | 1.00e+00 | 6.035 | 1 | 2 | 22 |
GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | 1.58e-02 | 1.00e+00 | 5.971 | 1 | 1 | 23 |
GO:0043388 | positive regulation of DNA binding | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 2 | 24 |
GO:0043425 | bHLH transcription factor binding | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 1 | 24 |
GO:0051059 | NF-kappaB binding | 1.72e-02 | 1.00e+00 | 5.850 | 1 | 3 | 25 |
GO:0031519 | PcG protein complex | 1.72e-02 | 1.00e+00 | 5.850 | 1 | 1 | 25 |
GO:0035329 | hippo signaling | 1.79e-02 | 1.00e+00 | 5.794 | 1 | 5 | 26 |
GO:0051209 | release of sequestered calcium ion into cytosol | 1.79e-02 | 1.00e+00 | 5.794 | 1 | 1 | 26 |
GO:0048565 | digestive tract development | 1.79e-02 | 1.00e+00 | 5.794 | 1 | 2 | 26 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 1.79e-02 | 1.00e+00 | 5.794 | 1 | 1 | 26 |
GO:0071339 | MLL1 complex | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 6 | 27 |
GO:0034612 | response to tumor necrosis factor | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 2 | 27 |
GO:0043967 | histone H4 acetylation | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 1 | 27 |
GO:0050714 | positive regulation of protein secretion | 1.93e-02 | 1.00e+00 | 5.687 | 1 | 3 | 28 |
GO:0005730 | nucleolus | 1.99e-02 | 1.00e+00 | 1.814 | 4 | 66 | 1641 |
GO:0034644 | cellular response to UV | 2.06e-02 | 1.00e+00 | 5.587 | 1 | 1 | 30 |
GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | 2.06e-02 | 1.00e+00 | 5.587 | 1 | 1 | 30 |
GO:0042594 | response to starvation | 2.13e-02 | 1.00e+00 | 5.540 | 1 | 4 | 31 |
GO:0043491 | protein kinase B signaling | 2.20e-02 | 1.00e+00 | 5.494 | 1 | 2 | 32 |
GO:1903507 | negative regulation of nucleic acid-templated transcription | 2.20e-02 | 1.00e+00 | 5.494 | 1 | 2 | 32 |
GO:0003723 | RNA binding | 2.22e-02 | 1.00e+00 | 3.076 | 2 | 18 | 342 |
GO:0071333 | cellular response to glucose stimulus | 2.27e-02 | 1.00e+00 | 5.450 | 1 | 1 | 33 |
GO:0001756 | somitogenesis | 2.27e-02 | 1.00e+00 | 5.450 | 1 | 1 | 33 |
GO:0043565 | sequence-specific DNA binding | 2.27e-02 | 1.00e+00 | 3.060 | 2 | 11 | 346 |
GO:0001102 | RNA polymerase II activating transcription factor binding | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 1 | 36 |
GO:0032092 | positive regulation of protein binding | 2.60e-02 | 1.00e+00 | 5.246 | 1 | 2 | 38 |
GO:0031490 | chromatin DNA binding | 2.60e-02 | 1.00e+00 | 5.246 | 1 | 2 | 38 |
GO:0050681 | androgen receptor binding | 2.60e-02 | 1.00e+00 | 5.246 | 1 | 1 | 38 |
GO:0035019 | somatic stem cell maintenance | 2.74e-02 | 1.00e+00 | 5.172 | 1 | 6 | 40 |
GO:0007519 | skeletal muscle tissue development | 2.74e-02 | 1.00e+00 | 5.172 | 1 | 2 | 40 |
GO:0046332 | SMAD binding | 2.74e-02 | 1.00e+00 | 5.172 | 1 | 2 | 40 |
GO:0071320 | cellular response to cAMP | 2.74e-02 | 1.00e+00 | 5.172 | 1 | 1 | 40 |
GO:0070301 | cellular response to hydrogen peroxide | 2.81e-02 | 1.00e+00 | 5.137 | 1 | 2 | 41 |
GO:0004402 | histone acetyltransferase activity | 2.94e-02 | 1.00e+00 | 5.068 | 1 | 6 | 43 |
GO:0045727 | positive regulation of translation | 3.01e-02 | 1.00e+00 | 5.035 | 1 | 2 | 44 |
GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding | 3.01e-02 | 1.00e+00 | 5.035 | 1 | 4 | 44 |
GO:0043966 | histone H3 acetylation | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 5 | 45 |
GO:0001047 | core promoter binding | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 5 | 45 |
GO:0043525 | positive regulation of neuron apoptotic process | 3.14e-02 | 1.00e+00 | 4.971 | 1 | 4 | 46 |
GO:0006366 | transcription from RNA polymerase II promoter | 3.25e-02 | 1.00e+00 | 2.783 | 2 | 30 | 419 |
GO:0035690 | cellular response to drug | 3.35e-02 | 1.00e+00 | 4.879 | 1 | 3 | 49 |
GO:0006986 | response to unfolded protein | 3.41e-02 | 1.00e+00 | 4.850 | 1 | 4 | 50 |
GO:0034976 | response to endoplasmic reticulum stress | 3.48e-02 | 1.00e+00 | 4.822 | 1 | 2 | 51 |
GO:0045454 | cell redox homeostasis | 3.48e-02 | 1.00e+00 | 4.822 | 1 | 1 | 51 |
GO:0009611 | response to wounding | 3.55e-02 | 1.00e+00 | 4.794 | 1 | 5 | 52 |
GO:0007623 | circadian rhythm | 3.62e-02 | 1.00e+00 | 4.766 | 1 | 1 | 53 |
GO:0071300 | cellular response to retinoic acid | 3.75e-02 | 1.00e+00 | 4.713 | 1 | 1 | 55 |
GO:0051592 | response to calcium ion | 3.75e-02 | 1.00e+00 | 4.713 | 1 | 1 | 55 |
GO:0000724 | double-strand break repair via homologous recombination | 3.75e-02 | 1.00e+00 | 4.713 | 1 | 2 | 55 |
GO:0002039 | p53 binding | 3.75e-02 | 1.00e+00 | 4.713 | 1 | 4 | 55 |
GO:0043627 | response to estrogen | 3.82e-02 | 1.00e+00 | 4.687 | 1 | 5 | 56 |
GO:0006396 | RNA processing | 4.02e-02 | 1.00e+00 | 4.612 | 1 | 5 | 59 |
GO:0001078 | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription | 4.02e-02 | 1.00e+00 | 4.612 | 1 | 5 | 59 |
GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity | 4.02e-02 | 1.00e+00 | 4.612 | 1 | 6 | 59 |
GO:0008013 | beta-catenin binding | 4.08e-02 | 1.00e+00 | 4.587 | 1 | 9 | 60 |
GO:0032481 | positive regulation of type I interferon production | 4.15e-02 | 1.00e+00 | 4.563 | 1 | 6 | 61 |
GO:0006987 | activation of signaling protein activity involved in unfolded protein response | 4.15e-02 | 1.00e+00 | 4.563 | 1 | 2 | 61 |
GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | 4.28e-02 | 1.00e+00 | 4.517 | 1 | 4 | 63 |
GO:0010468 | regulation of gene expression | 4.62e-02 | 1.00e+00 | 4.407 | 1 | 2 | 68 |
GO:0030324 | lung development | 4.88e-02 | 1.00e+00 | 4.324 | 1 | 1 | 72 |
GO:0000785 | chromatin | 4.95e-02 | 1.00e+00 | 4.304 | 1 | 6 | 73 |
GO:0000981 | sequence-specific DNA binding RNA polymerase II transcription factor activity | 5.02e-02 | 1.00e+00 | 4.285 | 1 | 4 | 74 |
GO:0002020 | protease binding | 5.02e-02 | 1.00e+00 | 4.285 | 1 | 6 | 74 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 5.08e-02 | 1.00e+00 | 4.265 | 1 | 1 | 75 |
GO:0001889 | liver development | 5.21e-02 | 1.00e+00 | 4.227 | 1 | 3 | 77 |
GO:0071013 | catalytic step 2 spliceosome | 5.28e-02 | 1.00e+00 | 4.209 | 1 | 7 | 78 |
GO:0030968 | endoplasmic reticulum unfolded protein response | 5.35e-02 | 1.00e+00 | 4.190 | 1 | 2 | 79 |
GO:0009653 | anatomical structure morphogenesis | 5.61e-02 | 1.00e+00 | 4.119 | 1 | 2 | 83 |
GO:0009952 | anterior/posterior pattern specification | 5.61e-02 | 1.00e+00 | 4.119 | 1 | 4 | 83 |
GO:0006464 | cellular protein modification process | 5.68e-02 | 1.00e+00 | 4.102 | 1 | 4 | 84 |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 5.69e-02 | 1.00e+00 | 2.339 | 2 | 37 | 570 |
GO:0009887 | organ morphogenesis | 5.81e-02 | 1.00e+00 | 4.068 | 1 | 5 | 86 |
GO:0090090 | negative regulation of canonical Wnt signaling pathway | 5.81e-02 | 1.00e+00 | 4.068 | 1 | 8 | 86 |
GO:0045471 | response to ethanol | 5.81e-02 | 1.00e+00 | 4.068 | 1 | 3 | 86 |
GO:0016363 | nuclear matrix | 6.14e-02 | 1.00e+00 | 3.986 | 1 | 6 | 91 |
GO:0001649 | osteoblast differentiation | 6.20e-02 | 1.00e+00 | 3.971 | 1 | 5 | 92 |
GO:0071456 | cellular response to hypoxia | 6.20e-02 | 1.00e+00 | 3.971 | 1 | 3 | 92 |
GO:0051091 | positive regulation of sequence-specific DNA binding transcription factor activity | 6.20e-02 | 1.00e+00 | 3.971 | 1 | 7 | 92 |
GO:0005770 | late endosome | 6.27e-02 | 1.00e+00 | 3.955 | 1 | 2 | 93 |
GO:0051726 | regulation of cell cycle | 6.53e-02 | 1.00e+00 | 3.894 | 1 | 5 | 97 |
GO:0001934 | positive regulation of protein phosphorylation | 6.98e-02 | 1.00e+00 | 3.794 | 1 | 5 | 104 |
GO:0030529 | ribonucleoprotein complex | 7.50e-02 | 1.00e+00 | 3.687 | 1 | 5 | 112 |
GO:0010467 | gene expression | 7.55e-02 | 1.00e+00 | 2.108 | 2 | 45 | 669 |
GO:0007219 | Notch signaling pathway | 8.02e-02 | 1.00e+00 | 3.587 | 1 | 5 | 120 |
GO:0006260 | DNA replication | 8.08e-02 | 1.00e+00 | 3.575 | 1 | 3 | 121 |
GO:0007050 | cell cycle arrest | 8.27e-02 | 1.00e+00 | 3.540 | 1 | 5 | 124 |
GO:0000086 | G2/M transition of mitotic cell cycle | 9.04e-02 | 1.00e+00 | 3.407 | 1 | 4 | 136 |
GO:0016055 | Wnt signaling pathway | 9.17e-02 | 1.00e+00 | 3.386 | 1 | 4 | 138 |
GO:0007507 | heart development | 9.23e-02 | 1.00e+00 | 3.375 | 1 | 7 | 139 |
GO:0001666 | response to hypoxia | 9.87e-02 | 1.00e+00 | 3.275 | 1 | 7 | 149 |
GO:0000398 | mRNA splicing, via spliceosome | 1.08e-01 | 1.00e+00 | 3.137 | 1 | 15 | 164 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.09e-01 | 1.00e+00 | 3.128 | 1 | 12 | 165 |
GO:0031625 | ubiquitin protein ligase binding | 1.17e-01 | 1.00e+00 | 3.018 | 1 | 5 | 178 |
GO:0032403 | protein complex binding | 1.20e-01 | 1.00e+00 | 2.978 | 1 | 6 | 183 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 1.21e-01 | 1.00e+00 | 2.971 | 1 | 22 | 184 |
GO:0008380 | RNA splicing | 1.47e-01 | 1.00e+00 | 2.661 | 1 | 22 | 228 |
GO:0007399 | nervous system development | 1.49e-01 | 1.00e+00 | 2.642 | 1 | 6 | 231 |
GO:0008270 | zinc ion binding | 1.49e-01 | 1.00e+00 | 1.533 | 2 | 27 | 997 |
GO:0044822 | poly(A) RNA binding | 1.63e-01 | 1.00e+00 | 1.450 | 2 | 50 | 1056 |
GO:0007283 | spermatogenesis | 1.68e-01 | 1.00e+00 | 2.461 | 1 | 3 | 262 |
GO:0006357 | regulation of transcription from RNA polymerase II promoter | 1.69e-01 | 1.00e+00 | 2.450 | 1 | 23 | 264 |
GO:0006954 | inflammatory response | 1.76e-01 | 1.00e+00 | 2.380 | 1 | 6 | 277 |
GO:0030154 | cell differentiation | 1.90e-01 | 1.00e+00 | 2.261 | 1 | 5 | 301 |
GO:0003682 | chromatin binding | 2.05e-01 | 1.00e+00 | 2.141 | 1 | 19 | 327 |
GO:0008283 | cell proliferation | 2.06e-01 | 1.00e+00 | 2.137 | 1 | 14 | 328 |
GO:0046982 | protein heterodimerization activity | 2.34e-01 | 1.00e+00 | 1.924 | 1 | 8 | 380 |
GO:0000278 | mitotic cell cycle | 2.40e-01 | 1.00e+00 | 1.883 | 1 | 15 | 391 |
GO:0005829 | cytosol | 2.43e-01 | 1.00e+00 | 0.794 | 3 | 86 | 2496 |
GO:0009986 | cell surface | 2.46e-01 | 1.00e+00 | 1.843 | 1 | 9 | 402 |
GO:0005737 | cytoplasm | 2.51e-01 | 1.00e+00 | 0.615 | 4 | 124 | 3767 |
GO:0045892 | negative regulation of transcription, DNA-templated | 2.52e-01 | 1.00e+00 | 1.804 | 1 | 24 | 413 |
GO:0044267 | cellular protein metabolic process | 2.84e-01 | 1.00e+00 | 1.605 | 1 | 20 | 474 |
GO:0045893 | positive regulation of transcription, DNA-templated | 2.86e-01 | 1.00e+00 | 1.593 | 1 | 24 | 478 |
GO:0016032 | viral process | 3.14e-01 | 1.00e+00 | 1.433 | 1 | 26 | 534 |
GO:0006915 | apoptotic process | 3.25e-01 | 1.00e+00 | 1.378 | 1 | 12 | 555 |
GO:0045087 | innate immune response | 3.44e-01 | 1.00e+00 | 1.275 | 1 | 15 | 596 |
GO:0005524 | ATP binding | 6.11e-01 | 1.00e+00 | 0.152 | 1 | 31 | 1298 |
GO:0046872 | metal ion binding | 6.13e-01 | 1.00e+00 | 0.142 | 1 | 29 | 1307 |
GO:0016020 | membrane | 7.11e-01 | 1.00e+00 | -0.221 | 1 | 46 | 1681 |