int-snw-4790

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.860	8.93e-16	3.58e-04	2.74e-03

chia-screen-data-Fav-int-snw-4790 subnetwork

Genes (14)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
TUBB4A	10382	7	-2.312	2.975	88	Yes	-
EP300	2033	22	-2.274	3.120	415	Yes	Yes
APLP2	334	12	-2.732	3.206	35	Yes	Yes
TPR	7175	18	-2.638	3.072	28	Yes	Yes
ANXA4	307	7	-2.478	3.062	15	Yes	Yes
ZFP36	7538	10	-2.968	2.869	24	Yes	Yes
[ NFKB1 ]	4790	9	-2.123	2.870	263	Yes	-
YAP1	10413	94	-4.256	3.538	53	Yes	-
APC	324	13	-2.293	3.004	353	Yes	-
NFRKB	4798	48	-3.129	3.108	23	Yes	Yes
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
YY1	7528	24	-2.572	3.120	114	Yes	Yes
ULK2	9706	9	-2.292	3.197	312	Yes	Yes
DDIT3	1649	60	-2.825	3.504	343	Yes	Yes

Interactions (19)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
NFRKB	4798	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
NFRKB	4798	YY1	7528	pp	--	int.I2D: BioGrid
EP300	2033	YY1	7528	pp	--	int.I2D: BioGrid, BCI, HPRD; int.Transfac: -; int.Ravasi: -; int.HPRD: in vivo; int.DIP: MI:0218(physical interaction)
EP300	2033	NFKB1	4790	pp	--	int.I2D: BioGrid
NFKB1	4790	YY1	7528	pp	--	int.Intact: MI:0915(physical association)
APC	324	TPR	7175	pp	--	int.Intact: MI:0915(physical association); int.I2D: BioGrid, IntAct, SOURAV_MAPK_HIGH
NFKB1	4790	ZFP36	7538	pp	--	int.I2D: BioGrid
DDIT3	1649	NFKB1	4790	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
NFKB1	4790	TUBB4A	10382	pp	--	int.I2D: MINT; int.Mint: MI:0915(physical association)
APLP2	334	NFKB1	4790	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
POU5F1	5460	TUBB4A	10382	pp	--	int.I2D: BioGrid
DDIT3	1649	TUBB4A	10382	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
ANXA4	307	NFKB1	4790	pp	--	int.I2D: BioGrid, INNATEDB
EP300	2033	YAP1	10413	pp	--	int.I2D: BioGrid
NFKB1	4790	ULK2	9706	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
NFKB1	4790	NFRKB	4798	pp	--	int.I2D: BCI, HPRD; int.Ravasi: -; int.HPRD: in vitro
APC	324	NFKB1	4790	pp	--	int.I2D: IntAct, SOURAV_MAPK_LOW
DDIT3	1649	EP300	2033	pp	--	int.Intact: MI:0915(physical association)
NFKB1	4790	TPR	7175	pp	--	int.I2D: MINT; int.Mint: MI:0915(physical association)

Related GO terms (417)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0044212	transcription regulatory region DNA binding	3.72e-07	5.36e-03	4.938	5	17	168
GO:0005634	nucleus	3.08e-06	4.44e-02	1.555	13	159	4559
GO:0042594	response to starvation	3.22e-06	4.65e-02	6.639	3	4	31
GO:0006974	cellular response to DNA damage stimulus	1.07e-05	1.54e-01	4.770	4	7	151
GO:0003677	DNA binding	6.08e-05	8.76e-01	2.566	7	49	1218
GO:0042789	mRNA transcription from RNA polymerase II promoter	6.78e-05	9.78e-01	7.308	2	2	13
GO:0008134	transcription factor binding	6.78e-05	9.78e-01	4.090	4	18	242
GO:0051019	mitogen-activated protein kinase binding	6.78e-05	9.78e-01	7.308	2	2	13
GO:0031011	Ino80 complex	7.91e-05	1.00e+00	7.201	2	6	14
GO:0005515	protein binding	1.00e-04	1.00e+00	1.153	13	198	6024
GO:0051276	chromosome organization	1.04e-04	1.00e+00	7.009	2	2	16
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	1.41e-04	1.00e+00	3.176	5	37	570
GO:0051059	NF-kappaB binding	2.59e-04	1.00e+00	6.365	2	3	25
GO:0005654	nucleoplasm	3.12e-04	1.00e+00	2.514	6	64	1082
GO:0003700	sequence-specific DNA binding transcription factor activity	3.66e-04	1.00e+00	2.882	5	39	699
GO:0007094	mitotic spindle assembly checkpoint	4.00e-04	1.00e+00	6.055	2	3	31
GO:0031072	heat shock protein binding	4.54e-04	1.00e+00	5.964	2	2	33
GO:0005667	transcription factor complex	5.79e-04	1.00e+00	4.142	3	17	175
GO:0003714	transcription corepressor activity	6.09e-04	1.00e+00	4.118	3	11	178
GO:0035019	somatic stem cell maintenance	6.68e-04	1.00e+00	5.687	2	6	40
GO:0005829	cytosol	8.87e-04	1.00e+00	1.723	8	86	2496
GO:1901673	regulation of spindle assembly involved in mitosis	9.71e-04	1.00e+00	10.009	1	1	1
GO:0043578	nuclear matrix organization	9.71e-04	1.00e+00	10.009	1	1	1
GO:2000016	negative regulation of determination of dorsal identity	9.71e-04	1.00e+00	10.009	1	1	1
GO:1901985	positive regulation of protein acetylation	9.71e-04	1.00e+00	10.009	1	1	1
GO:0010965	regulation of mitotic sister chromatid separation	9.71e-04	1.00e+00	10.009	1	1	1
GO:0043969	histone H2B acetylation	9.71e-04	1.00e+00	10.009	1	1	1
GO:0045083	negative regulation of interleukin-12 biosynthetic process	9.71e-04	1.00e+00	10.009	1	1	1
GO:0006404	RNA import into nucleus	9.71e-04	1.00e+00	10.009	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	9.71e-04	1.00e+00	10.009	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	9.71e-04	1.00e+00	10.009	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	9.71e-04	1.00e+00	10.009	1	1	1
GO:0042483	negative regulation of odontogenesis	9.71e-04	1.00e+00	10.009	1	1	1
GO:0060795	cell fate commitment involved in formation of primary germ layer	9.71e-04	1.00e+00	10.009	1	1	1
GO:0060177	regulation of angiotensin metabolic process	9.71e-04	1.00e+00	10.009	1	1	1
GO:0051171	regulation of nitrogen compound metabolic process	9.71e-04	1.00e+00	10.009	1	1	1
GO:2000629	negative regulation of miRNA metabolic process	9.71e-04	1.00e+00	10.009	1	1	1
GO:0031453	positive regulation of heterochromatin assembly	9.71e-04	1.00e+00	10.009	1	1	1
GO:0050728	negative regulation of inflammatory response	1.31e-03	1.00e+00	5.201	2	3	56
GO:0003713	transcription coactivator activity	1.39e-03	1.00e+00	3.705	3	24	237
GO:0008013	beta-catenin binding	1.50e-03	1.00e+00	5.102	2	9	60
GO:0032481	positive regulation of type I interferon production	1.55e-03	1.00e+00	5.078	2	6	61
GO:0000776	kinetochore	1.65e-03	1.00e+00	5.031	2	5	63
GO:0006355	regulation of transcription, DNA-templated	1.85e-03	1.00e+00	2.369	5	43	997
GO:0060242	contact inhibition	1.94e-03	1.00e+00	9.009	1	1	2
GO:0031990	mRNA export from nucleus in response to heat stress	1.94e-03	1.00e+00	9.009	1	2	2
GO:0006403	RNA localization	1.94e-03	1.00e+00	9.009	1	1	2
GO:0044337	canonical Wnt signaling pathway involved in positive regulation of apoptotic process	1.94e-03	1.00e+00	9.009	1	1	2
GO:2000483	negative regulation of interleukin-8 secretion	1.94e-03	1.00e+00	9.009	1	1	2
GO:0009786	regulation of asymmetric cell division	1.94e-03	1.00e+00	9.009	1	1	2
GO:0070840	dynein complex binding	1.94e-03	1.00e+00	9.009	1	1	2
GO:0090043	regulation of tubulin deacetylation	1.94e-03	1.00e+00	9.009	1	2	2
GO:0071389	cellular response to mineralocorticoid stimulus	1.94e-03	1.00e+00	9.009	1	1	2
GO:0046832	negative regulation of RNA export from nucleus	1.94e-03	1.00e+00	9.009	1	1	2
GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	1.94e-03	1.00e+00	9.009	1	1	2
GO:0034696	response to prostaglandin F	1.94e-03	1.00e+00	9.009	1	1	2
GO:0000189	MAPK import into nucleus	1.94e-03	1.00e+00	9.009	1	1	2
GO:0014737	positive regulation of muscle atrophy	1.94e-03	1.00e+00	9.009	1	1	2
GO:0035984	cellular response to trichostatin A	1.94e-03	1.00e+00	9.009	1	1	2
GO:0009798	axis specification	1.94e-03	1.00e+00	9.009	1	1	2
GO:0044324	regulation of transcription involved in anterior/posterior axis specification	1.94e-03	1.00e+00	9.009	1	1	2
GO:0003729	mRNA binding	2.15e-03	1.00e+00	4.839	2	4	72
GO:0009952	anterior/posterior pattern specification	2.85e-03	1.00e+00	4.634	2	4	83
GO:0018076	N-terminal peptidyl-lysine acetylation	2.91e-03	1.00e+00	8.424	1	1	3
GO:0046914	transition metal ion binding	2.91e-03	1.00e+00	8.424	1	1	3
GO:0042306	regulation of protein import into nucleus	2.91e-03	1.00e+00	8.424	1	2	3
GO:0060913	cardiac cell fate determination	2.91e-03	1.00e+00	8.424	1	1	3
GO:1900127	positive regulation of hyaluronan biosynthetic process	2.91e-03	1.00e+00	8.424	1	1	3
GO:0050779	RNA destabilization	2.91e-03	1.00e+00	8.424	1	1	3
GO:0010560	positive regulation of glycoprotein biosynthetic process	2.91e-03	1.00e+00	8.424	1	1	3
GO:0010956	negative regulation of calcidiol 1-monooxygenase activity	2.91e-03	1.00e+00	8.424	1	1	3
GO:0033256	I-kappaB/NF-kappaB complex	2.91e-03	1.00e+00	8.424	1	1	3
GO:0006405	RNA export from nucleus	2.91e-03	1.00e+00	8.424	1	2	3
GO:0003130	BMP signaling pathway involved in heart induction	2.91e-03	1.00e+00	8.424	1	1	3
GO:0090090	negative regulation of canonical Wnt signaling pathway	3.05e-03	1.00e+00	4.582	2	8	86
GO:0032680	regulation of tumor necrosis factor production	3.88e-03	1.00e+00	8.009	1	1	4
GO:0032375	negative regulation of cholesterol transport	3.88e-03	1.00e+00	8.009	1	1	4
GO:0097157	pre-mRNA intronic binding	3.88e-03	1.00e+00	8.009	1	1	4
GO:0034273	ATG1/UKL1 signaling complex	3.88e-03	1.00e+00	8.009	1	1	4
GO:0018393	internal peptidyl-lysine acetylation	3.88e-03	1.00e+00	8.009	1	1	4
GO:0010957	negative regulation of vitamin D biosynthetic process	3.88e-03	1.00e+00	8.009	1	1	4
GO:0032269	negative regulation of cellular protein metabolic process	3.88e-03	1.00e+00	8.009	1	1	4
GO:2000630	positive regulation of miRNA metabolic process	3.88e-03	1.00e+00	8.009	1	1	4
GO:0006999	nuclear pore organization	3.88e-03	1.00e+00	8.009	1	1	4
GO:0033269	internode region of axon	3.88e-03	1.00e+00	8.009	1	1	4
GO:0044615	nuclear pore nuclear basket	3.88e-03	1.00e+00	8.009	1	1	4
GO:0019887	protein kinase regulator activity	3.88e-03	1.00e+00	8.009	1	1	4
GO:0001714	endodermal cell fate specification	4.84e-03	1.00e+00	7.687	1	1	5
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	4.84e-03	1.00e+00	7.687	1	1	5
GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process	4.84e-03	1.00e+00	7.687	1	2	5
GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	4.84e-03	1.00e+00	7.687	1	1	5
GO:0019957	C-C chemokine binding	4.84e-03	1.00e+00	7.687	1	1	5
GO:0043620	regulation of DNA-templated transcription in response to stress	4.84e-03	1.00e+00	7.687	1	1	5
GO:0010884	positive regulation of lipid storage	4.84e-03	1.00e+00	7.687	1	1	5
GO:0035925	mRNA 3'-UTR AU-rich region binding	4.84e-03	1.00e+00	7.687	1	1	5
GO:0065004	protein-DNA complex assembly	4.84e-03	1.00e+00	7.687	1	1	5
GO:0010793	regulation of mRNA export from nucleus	4.84e-03	1.00e+00	7.687	1	1	5
GO:0048671	negative regulation of collateral sprouting	4.84e-03	1.00e+00	7.687	1	1	5
GO:0060298	positive regulation of sarcomere organization	4.84e-03	1.00e+00	7.687	1	1	5
GO:0070849	response to epidermal growth factor	4.84e-03	1.00e+00	7.687	1	1	5
GO:0007176	regulation of epidermal growth factor-activated receptor activity	4.84e-03	1.00e+00	7.687	1	1	5
GO:0032025	response to cobalt ion	4.84e-03	1.00e+00	7.687	1	1	5
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	5.72e-03	1.00e+00	2.385	4	41	789
GO:0000278	mitotic cell cycle	5.76e-03	1.00e+00	2.983	3	15	391
GO:0030858	positive regulation of epithelial cell differentiation	5.81e-03	1.00e+00	7.424	1	1	6
GO:0004859	phospholipase inhibitor activity	5.81e-03	1.00e+00	7.424	1	1	6
GO:0007050	cell cycle arrest	6.24e-03	1.00e+00	4.055	2	5	124
GO:0007091	metaphase/anaphase transition of mitotic cell cycle	6.78e-03	1.00e+00	7.201	1	2	7
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	6.78e-03	1.00e+00	7.201	1	1	7
GO:0046825	regulation of protein export from nucleus	6.78e-03	1.00e+00	7.201	1	2	7
GO:0071354	cellular response to interleukin-6	6.78e-03	1.00e+00	7.201	1	2	7
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	6.78e-03	1.00e+00	7.201	1	2	7
GO:0006475	internal protein amino acid acetylation	6.78e-03	1.00e+00	7.201	1	1	7
GO:0006366	transcription from RNA polymerase II promoter	6.98e-03	1.00e+00	2.883	3	30	419
GO:0000086	G2/M transition of mitotic cell cycle	7.46e-03	1.00e+00	3.921	2	4	136
GO:0045670	regulation of osteoclast differentiation	7.74e-03	1.00e+00	7.009	1	2	8
GO:0051292	nuclear pore complex assembly	7.74e-03	1.00e+00	7.009	1	4	8
GO:0007617	mating behavior	7.74e-03	1.00e+00	7.009	1	1	8
GO:0001955	blood vessel maturation	7.74e-03	1.00e+00	7.009	1	1	8
GO:0071316	cellular response to nicotine	7.74e-03	1.00e+00	7.009	1	1	8
GO:0035457	cellular response to interferon-alpha	7.74e-03	1.00e+00	7.009	1	1	8
GO:0045667	regulation of osteoblast differentiation	8.70e-03	1.00e+00	6.839	1	1	9
GO:0042405	nuclear inclusion body	8.70e-03	1.00e+00	6.839	1	2	9
GO:0035259	glucocorticoid receptor binding	8.70e-03	1.00e+00	6.839	1	1	9
GO:0000975	regulatory region DNA binding	8.70e-03	1.00e+00	6.839	1	2	9
GO:0045793	positive regulation of cell size	8.70e-03	1.00e+00	6.839	1	2	9
GO:0060765	regulation of androgen receptor signaling pathway	8.70e-03	1.00e+00	6.839	1	1	9
GO:0010225	response to UV-C	8.70e-03	1.00e+00	6.839	1	2	9
GO:0035278	negative regulation of translation involved in gene silencing by miRNA	8.70e-03	1.00e+00	6.839	1	1	9
GO:0006983	ER overload response	8.70e-03	1.00e+00	6.839	1	1	9
GO:0043495	protein anchor	8.70e-03	1.00e+00	6.839	1	1	9
GO:0000400	four-way junction DNA binding	8.70e-03	1.00e+00	6.839	1	1	9
GO:0031274	positive regulation of pseudopodium assembly	9.67e-03	1.00e+00	6.687	1	2	10
GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	9.67e-03	1.00e+00	6.687	1	2	10
GO:0035413	positive regulation of catenin import into nucleus	9.67e-03	1.00e+00	6.687	1	2	10
GO:0016407	acetyltransferase activity	9.67e-03	1.00e+00	6.687	1	2	10
GO:0030877	beta-catenin destruction complex	9.67e-03	1.00e+00	6.687	1	2	10
GO:0051010	microtubule plus-end binding	1.06e-02	1.00e+00	6.549	1	1	11
GO:0045662	negative regulation of myoblast differentiation	1.06e-02	1.00e+00	6.549	1	3	11
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	1.06e-02	1.00e+00	6.549	1	2	11
GO:0031116	positive regulation of microtubule polymerization	1.06e-02	1.00e+00	6.549	1	1	11
GO:0043923	positive regulation by host of viral transcription	1.06e-02	1.00e+00	6.549	1	1	11
GO:0033160	positive regulation of protein import into nucleus, translocation	1.06e-02	1.00e+00	6.549	1	3	11
GO:0042975	peroxisome proliferator activated receptor binding	1.06e-02	1.00e+00	6.549	1	1	11
GO:0060391	positive regulation of SMAD protein import into nucleus	1.06e-02	1.00e+00	6.549	1	4	11
GO:0031965	nuclear membrane	1.12e-02	1.00e+00	3.616	2	10	168
GO:0006878	cellular copper ion homeostasis	1.16e-02	1.00e+00	6.424	1	1	12
GO:0032886	regulation of microtubule-based process	1.16e-02	1.00e+00	6.424	1	1	12
GO:0006402	mRNA catabolic process	1.16e-02	1.00e+00	6.424	1	1	12
GO:0045947	negative regulation of translational initiation	1.16e-02	1.00e+00	6.424	1	2	12
GO:0070935	3'-UTR-mediated mRNA stabilization	1.16e-02	1.00e+00	6.424	1	3	12
GO:0045295	gamma-catenin binding	1.16e-02	1.00e+00	6.424	1	1	12
GO:0034045	pre-autophagosomal structure membrane	1.16e-02	1.00e+00	6.424	1	2	12
GO:0034399	nuclear periphery	1.16e-02	1.00e+00	6.424	1	5	12
GO:0035198	miRNA binding	1.16e-02	1.00e+00	6.424	1	1	12
GO:0071480	cellular response to gamma radiation	1.26e-02	1.00e+00	6.308	1	1	13
GO:0016746	transferase activity, transferring acyl groups	1.26e-02	1.00e+00	6.308	1	1	13
GO:0046688	response to copper ion	1.26e-02	1.00e+00	6.308	1	1	13
GO:0044295	axonal growth cone	1.26e-02	1.00e+00	6.308	1	1	13
GO:0043409	negative regulation of MAPK cascade	1.26e-02	1.00e+00	6.308	1	2	13
GO:0005868	cytoplasmic dynein complex	1.26e-02	1.00e+00	6.308	1	1	13
GO:0046827	positive regulation of protein export from nucleus	1.26e-02	1.00e+00	6.308	1	1	13
GO:0010744	positive regulation of macrophage derived foam cell differentiation	1.35e-02	1.00e+00	6.201	1	1	14
GO:0035371	microtubule plus-end	1.35e-02	1.00e+00	6.201	1	1	14
GO:0001967	suckling behavior	1.35e-02	1.00e+00	6.201	1	1	14
GO:0005737	cytoplasm	1.35e-02	1.00e+00	1.130	8	124	3767
GO:0031293	membrane protein intracellular domain proteolysis	1.35e-02	1.00e+00	6.201	1	1	14
GO:0017091	AU-rich element binding	1.35e-02	1.00e+00	6.201	1	2	14
GO:0070542	response to fatty acid	1.35e-02	1.00e+00	6.201	1	1	14
GO:0071375	cellular response to peptide hormone stimulus	1.35e-02	1.00e+00	6.201	1	2	14
GO:0032993	protein-DNA complex	1.35e-02	1.00e+00	6.201	1	2	14
GO:0005487	nucleocytoplasmic transporter activity	1.35e-02	1.00e+00	6.201	1	3	14
GO:0042307	positive regulation of protein import into nucleus	1.45e-02	1.00e+00	6.102	1	4	15
GO:0001824	blastocyst development	1.45e-02	1.00e+00	6.102	1	2	15
GO:1990090	cellular response to nerve growth factor stimulus	1.45e-02	1.00e+00	6.102	1	1	15
GO:0006915	apoptotic process	1.50e-02	1.00e+00	2.477	3	12	555
GO:0007026	negative regulation of microtubule depolymerization	1.54e-02	1.00e+00	6.009	1	1	16
GO:0043209	myelin sheath	1.54e-02	1.00e+00	6.009	1	1	16
GO:0046716	muscle cell cellular homeostasis	1.54e-02	1.00e+00	6.009	1	1	16
GO:0045638	negative regulation of myeloid cell differentiation	1.54e-02	1.00e+00	6.009	1	1	16
GO:0048593	camera-type eye morphogenesis	1.54e-02	1.00e+00	6.009	1	1	16
GO:0012506	vesicle membrane	1.64e-02	1.00e+00	5.921	1	1	17
GO:0090316	positive regulation of intracellular protein transport	1.64e-02	1.00e+00	5.921	1	2	17
GO:0071889	14-3-3 protein binding	1.73e-02	1.00e+00	5.839	1	2	18
GO:0031122	cytoplasmic microtubule organization	1.73e-02	1.00e+00	5.839	1	1	18
GO:0045773	positive regulation of axon extension	1.73e-02	1.00e+00	5.839	1	1	18
GO:0033613	activating transcription factor binding	1.73e-02	1.00e+00	5.839	1	3	18
GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	1.83e-02	1.00e+00	5.761	1	2	19
GO:0035257	nuclear hormone receptor binding	1.83e-02	1.00e+00	5.761	1	1	19
GO:0071549	cellular response to dexamethasone stimulus	1.92e-02	1.00e+00	5.687	1	3	20
GO:0010942	positive regulation of cell death	1.92e-02	1.00e+00	5.687	1	1	20
GO:0032757	positive regulation of interleukin-8 production	1.92e-02	1.00e+00	5.687	1	1	20
GO:0043393	regulation of protein binding	1.92e-02	1.00e+00	5.687	1	1	20
GO:0048675	axon extension	2.02e-02	1.00e+00	5.616	1	2	21
GO:0032967	positive regulation of collagen biosynthetic process	2.02e-02	1.00e+00	5.616	1	3	21
GO:0045862	positive regulation of proteolysis	2.02e-02	1.00e+00	5.616	1	2	21
GO:0000123	histone acetyltransferase complex	2.02e-02	1.00e+00	5.616	1	6	21
GO:0009954	proximal/distal pattern formation	2.02e-02	1.00e+00	5.616	1	1	21
GO:0000281	mitotic cytokinesis	2.02e-02	1.00e+00	5.616	1	2	21
GO:0003823	antigen binding	2.12e-02	1.00e+00	5.549	1	2	22
GO:0010506	regulation of autophagy	2.21e-02	1.00e+00	5.485	1	2	23
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	2.21e-02	1.00e+00	5.485	1	1	23
GO:0043388	positive regulation of DNA binding	2.31e-02	1.00e+00	5.424	1	2	24
GO:0045296	cadherin binding	2.31e-02	1.00e+00	5.424	1	3	24
GO:0043425	bHLH transcription factor binding	2.31e-02	1.00e+00	5.424	1	1	24
GO:0006611	protein export from nucleus	2.40e-02	1.00e+00	5.365	1	3	25
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	2.40e-02	1.00e+00	5.365	1	3	25
GO:0031519	PcG protein complex	2.40e-02	1.00e+00	5.365	1	1	25
GO:0035329	hippo signaling	2.50e-02	1.00e+00	5.308	1	5	26
GO:0000045	autophagic vacuole assembly	2.50e-02	1.00e+00	5.308	1	2	26
GO:0000976	transcription regulatory region sequence-specific DNA binding	2.50e-02	1.00e+00	5.308	1	3	26
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	2.50e-02	1.00e+00	5.308	1	1	26
GO:0051209	release of sequestered calcium ion into cytosol	2.50e-02	1.00e+00	5.308	1	1	26
GO:0048565	digestive tract development	2.50e-02	1.00e+00	5.308	1	2	26
GO:0015631	tubulin binding	2.59e-02	1.00e+00	5.254	1	2	27
GO:0034612	response to tumor necrosis factor	2.59e-02	1.00e+00	5.254	1	2	27
GO:0007017	microtubule-based process	2.59e-02	1.00e+00	5.254	1	2	27
GO:0043967	histone H4 acetylation	2.59e-02	1.00e+00	5.254	1	1	27
GO:0051258	protein polymerization	2.59e-02	1.00e+00	5.254	1	2	27
GO:0006357	regulation of transcription from RNA polymerase II promoter	2.63e-02	1.00e+00	2.964	2	23	264
GO:0003727	single-stranded RNA binding	2.69e-02	1.00e+00	5.201	1	2	28
GO:0050714	positive regulation of protein secretion	2.69e-02	1.00e+00	5.201	1	3	28
GO:0034605	cellular response to heat	2.69e-02	1.00e+00	5.201	1	1	28
GO:0070830	tight junction assembly	2.69e-02	1.00e+00	5.201	1	1	28
GO:0005913	cell-cell adherens junction	2.78e-02	1.00e+00	5.151	1	3	29
GO:0030901	midbrain development	2.78e-02	1.00e+00	5.151	1	1	29
GO:0072686	mitotic spindle	2.78e-02	1.00e+00	5.151	1	3	29
GO:0006606	protein import into nucleus	2.87e-02	1.00e+00	5.102	1	2	30
GO:0031647	regulation of protein stability	2.87e-02	1.00e+00	5.102	1	4	30
GO:0010827	regulation of glucose transport	2.87e-02	1.00e+00	5.102	1	4	30
GO:0006954	inflammatory response	2.87e-02	1.00e+00	2.895	2	6	277
GO:0034644	cellular response to UV	2.87e-02	1.00e+00	5.102	1	1	30
GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	2.87e-02	1.00e+00	5.102	1	1	30
GO:0005544	calcium-dependent phospholipid binding	2.87e-02	1.00e+00	5.102	1	1	30
GO:0010494	cytoplasmic stress granule	2.87e-02	1.00e+00	5.102	1	2	30
GO:0009953	dorsal/ventral pattern formation	2.97e-02	1.00e+00	5.055	1	2	31
GO:0071347	cellular response to interleukin-1	2.97e-02	1.00e+00	5.055	1	2	31
GO:0043491	protein kinase B signaling	3.06e-02	1.00e+00	5.009	1	2	32
GO:1903507	negative regulation of nucleic acid-templated transcription	3.06e-02	1.00e+00	5.009	1	2	32
GO:0001756	somitogenesis	3.16e-02	1.00e+00	4.964	1	1	33
GO:0033077	T cell differentiation in thymus	3.16e-02	1.00e+00	4.964	1	1	33
GO:0071333	cellular response to glucose stimulus	3.16e-02	1.00e+00	4.964	1	1	33
GO:0001942	hair follicle development	3.35e-02	1.00e+00	4.879	1	2	35
GO:0007077	mitotic nuclear envelope disassembly	3.44e-02	1.00e+00	4.839	1	4	36
GO:0001102	RNA polymerase II activating transcription factor binding	3.44e-02	1.00e+00	4.839	1	1	36
GO:0048538	thymus development	3.44e-02	1.00e+00	4.839	1	2	36
GO:0051084	'de novo' posttranslational protein folding	3.53e-02	1.00e+00	4.799	1	5	37
GO:0031490	chromatin DNA binding	3.63e-02	1.00e+00	4.761	1	2	38
GO:0032092	positive regulation of protein binding	3.63e-02	1.00e+00	4.761	1	2	38
GO:0050681	androgen receptor binding	3.63e-02	1.00e+00	4.761	1	1	38
GO:0019901	protein kinase binding	3.68e-02	1.00e+00	2.700	2	18	317
GO:0008645	hexose transport	3.72e-02	1.00e+00	4.723	1	4	39
GO:0051781	positive regulation of cell division	3.72e-02	1.00e+00	4.723	1	1	39
GO:0005881	cytoplasmic microtubule	3.82e-02	1.00e+00	4.687	1	1	40
GO:0045785	positive regulation of cell adhesion	3.82e-02	1.00e+00	4.687	1	2	40
GO:0046332	SMAD binding	3.82e-02	1.00e+00	4.687	1	2	40
GO:0071320	cellular response to cAMP	3.82e-02	1.00e+00	4.687	1	1	40
GO:0050885	neuromuscular process controlling balance	3.82e-02	1.00e+00	4.687	1	2	40
GO:0007519	skeletal muscle tissue development	3.82e-02	1.00e+00	4.687	1	2	40
GO:0003682	chromatin binding	3.90e-02	1.00e+00	2.656	2	19	327
GO:0070301	cellular response to hydrogen peroxide	3.91e-02	1.00e+00	4.651	1	2	41
GO:0019898	extrinsic component of membrane	4.00e-02	1.00e+00	4.616	1	2	42
GO:0004402	histone acetyltransferase activity	4.10e-02	1.00e+00	4.582	1	6	43
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	4.19e-02	1.00e+00	4.549	1	4	44
GO:0045727	positive regulation of translation	4.19e-02	1.00e+00	4.549	1	2	44
GO:0043966	histone H3 acetylation	4.28e-02	1.00e+00	4.517	1	5	45
GO:0001047	core promoter binding	4.28e-02	1.00e+00	4.517	1	5	45
GO:0043565	sequence-specific DNA binding	4.32e-02	1.00e+00	2.574	2	11	346
GO:0016328	lateral plasma membrane	4.38e-02	1.00e+00	4.485	1	3	46
GO:0043525	positive regulation of neuron apoptotic process	4.38e-02	1.00e+00	4.485	1	4	46
GO:0006921	cellular component disassembly involved in execution phase of apoptosis	4.47e-02	1.00e+00	4.454	1	2	47
GO:0090263	positive regulation of canonical Wnt signaling pathway	4.56e-02	1.00e+00	4.424	1	3	48
GO:0030900	forebrain development	4.65e-02	1.00e+00	4.394	1	1	49
GO:0035690	cellular response to drug	4.65e-02	1.00e+00	4.394	1	3	49
GO:0006986	response to unfolded protein	4.75e-02	1.00e+00	4.365	1	4	50
GO:0045732	positive regulation of protein catabolic process	4.75e-02	1.00e+00	4.365	1	1	50
GO:0060041	retina development in camera-type eye	4.84e-02	1.00e+00	4.336	1	2	51
GO:0034976	response to endoplasmic reticulum stress	4.84e-02	1.00e+00	4.336	1	2	51
GO:0045454	cell redox homeostasis	4.84e-02	1.00e+00	4.336	1	1	51
GO:0009611	response to wounding	4.93e-02	1.00e+00	4.308	1	5	52
GO:0007623	circadian rhythm	5.03e-02	1.00e+00	4.281	1	1	53
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	5.03e-02	1.00e+00	4.281	1	4	53
GO:0051592	response to calcium ion	5.21e-02	1.00e+00	4.227	1	1	55
GO:0002039	p53 binding	5.21e-02	1.00e+00	4.227	1	4	55
GO:0015758	glucose transport	5.21e-02	1.00e+00	4.227	1	4	55
GO:0071300	cellular response to retinoic acid	5.21e-02	1.00e+00	4.227	1	1	55
GO:0000724	double-strand break repair via homologous recombination	5.21e-02	1.00e+00	4.227	1	2	55
GO:0043627	response to estrogen	5.30e-02	1.00e+00	4.201	1	5	56
GO:0048306	calcium-dependent protein binding	5.30e-02	1.00e+00	4.201	1	2	56
GO:0008203	cholesterol metabolic process	5.40e-02	1.00e+00	4.176	1	2	57
GO:0005643	nuclear pore	5.40e-02	1.00e+00	4.176	1	11	57
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	5.58e-02	1.00e+00	4.126	1	6	59
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	5.58e-02	1.00e+00	4.126	1	5	59
GO:0030855	epithelial cell differentiation	5.76e-02	1.00e+00	4.078	1	1	61
GO:0006987	activation of signaling protein activity involved in unfolded protein response	5.76e-02	1.00e+00	4.078	1	2	61
GO:0032088	negative regulation of NF-kappaB transcription factor activity	5.95e-02	1.00e+00	4.031	1	3	63
GO:0004867	serine-type endopeptidase inhibitor activity	5.95e-02	1.00e+00	4.031	1	3	63
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	5.95e-02	1.00e+00	4.031	1	4	63
GO:0006310	DNA recombination	6.13e-02	1.00e+00	3.986	1	7	65
GO:0071260	cellular response to mechanical stimulus	6.13e-02	1.00e+00	3.986	1	4	65
GO:0034166	toll-like receptor 10 signaling pathway	6.13e-02	1.00e+00	3.986	1	4	65
GO:0007409	axonogenesis	6.13e-02	1.00e+00	3.986	1	2	65
GO:0034146	toll-like receptor 5 signaling pathway	6.13e-02	1.00e+00	3.986	1	4	65
GO:0043066	negative regulation of apoptotic process	6.21e-02	1.00e+00	2.281	2	16	424
GO:0010468	regulation of gene expression	6.40e-02	1.00e+00	3.921	1	2	68
GO:0032587	ruffle membrane	6.59e-02	1.00e+00	3.879	1	3	70
GO:0038123	toll-like receptor TLR1:TLR2 signaling pathway	6.68e-02	1.00e+00	3.859	1	4	71
GO:0007626	locomotory behavior	6.68e-02	1.00e+00	3.859	1	2	71
GO:0038124	toll-like receptor TLR6:TLR2 signaling pathway	6.68e-02	1.00e+00	3.859	1	4	71
GO:0043086	negative regulation of catalytic activity	6.77e-02	1.00e+00	3.839	1	2	72
GO:0034162	toll-like receptor 9 signaling pathway	6.77e-02	1.00e+00	3.839	1	4	72
GO:0030324	lung development	6.77e-02	1.00e+00	3.839	1	1	72
GO:0034134	toll-like receptor 2 signaling pathway	6.86e-02	1.00e+00	3.819	1	4	73
GO:0000785	chromatin	6.86e-02	1.00e+00	3.819	1	6	73
GO:0002020	protease binding	6.95e-02	1.00e+00	3.799	1	6	74
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	6.95e-02	1.00e+00	3.799	1	4	74
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	7.04e-02	1.00e+00	3.780	1	1	75
GO:0060070	canonical Wnt signaling pathway	7.04e-02	1.00e+00	3.780	1	4	75
GO:0035666	TRIF-dependent toll-like receptor signaling pathway	7.13e-02	1.00e+00	3.761	1	3	76
GO:0001889	liver development	7.22e-02	1.00e+00	3.742	1	3	77
GO:0005929	cilium	7.22e-02	1.00e+00	3.742	1	2	77
GO:0001822	kidney development	7.31e-02	1.00e+00	3.723	1	3	78
GO:0002756	MyD88-independent toll-like receptor signaling pathway	7.31e-02	1.00e+00	3.723	1	3	78
GO:0034138	toll-like receptor 3 signaling pathway	7.40e-02	1.00e+00	3.705	1	3	79
GO:0030968	endoplasmic reticulum unfolded protein response	7.40e-02	1.00e+00	3.705	1	2	79
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	7.49e-02	1.00e+00	3.687	1	5	80
GO:0044267	cellular protein metabolic process	7.56e-02	1.00e+00	2.120	2	20	474
GO:0071222	cellular response to lipopolysaccharide	7.59e-02	1.00e+00	3.669	1	4	81
GO:0045893	positive regulation of transcription, DNA-templated	7.67e-02	1.00e+00	2.108	2	24	478
GO:0009653	anatomical structure morphogenesis	7.77e-02	1.00e+00	3.634	1	2	83
GO:0044822	poly(A) RNA binding	7.77e-02	1.00e+00	1.549	3	50	1056
GO:0042802	identical protein binding	7.84e-02	1.00e+00	2.090	2	19	484
GO:0050852	T cell receptor signaling pathway	7.95e-02	1.00e+00	3.599	1	2	85
GO:0005923	tight junction	8.04e-02	1.00e+00	3.582	1	2	86
GO:0009887	organ morphogenesis	8.04e-02	1.00e+00	3.582	1	5	86
GO:0003690	double-stranded DNA binding	8.04e-02	1.00e+00	3.582	1	3	86
GO:0045471	response to ethanol	8.04e-02	1.00e+00	3.582	1	3	86
GO:0006979	response to oxidative stress	8.13e-02	1.00e+00	3.566	1	6	87
GO:0016363	nuclear matrix	8.48e-02	1.00e+00	3.501	1	6	91
GO:0005200	structural constituent of cytoskeleton	8.48e-02	1.00e+00	3.501	1	6	91
GO:0071456	cellular response to hypoxia	8.57e-02	1.00e+00	3.485	1	3	92
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	8.57e-02	1.00e+00	3.485	1	7	92
GO:0005770	late endosome	8.66e-02	1.00e+00	3.470	1	2	93
GO:0034142	toll-like receptor 4 signaling pathway	8.93e-02	1.00e+00	3.424	1	4	96
GO:0051726	regulation of cell cycle	9.02e-02	1.00e+00	3.409	1	5	97
GO:0016032	viral process	9.28e-02	1.00e+00	1.948	2	26	534
GO:0030659	cytoplasmic vesicle membrane	9.37e-02	1.00e+00	3.351	1	2	101
GO:0001934	positive regulation of protein phosphorylation	9.64e-02	1.00e+00	3.308	1	5	104
GO:0010951	negative regulation of endopeptidase activity	9.64e-02	1.00e+00	3.308	1	6	104
GO:0002224	toll-like receptor signaling pathway	1.01e-01	1.00e+00	3.241	1	4	109
GO:0006461	protein complex assembly	1.03e-01	1.00e+00	3.214	1	4	111
GO:0005635	nuclear envelope	1.04e-01	1.00e+00	3.189	1	5	113
GO:0006325	chromatin organization	1.09e-01	1.00e+00	3.126	1	12	118
GO:0007219	Notch signaling pathway	1.10e-01	1.00e+00	3.102	1	5	120
GO:0042803	protein homodimerization activity	1.11e-01	1.00e+00	1.792	2	19	595
GO:0045087	innate immune response	1.12e-01	1.00e+00	1.790	2	15	596
GO:0008201	heparin binding	1.12e-01	1.00e+00	3.078	1	1	122
GO:0051092	positive regulation of NF-kappaB transcription factor activity	1.14e-01	1.00e+00	3.055	1	5	124
GO:0030027	lamellipodium	1.15e-01	1.00e+00	3.043	1	7	125
GO:0016477	cell migration	1.17e-01	1.00e+00	3.009	1	4	128
GO:0030335	positive regulation of cell migration	1.17e-01	1.00e+00	3.020	1	5	127
GO:0005215	transporter activity	1.19e-01	1.00e+00	2.986	1	3	130
GO:0016055	Wnt signaling pathway	1.26e-01	1.00e+00	2.900	1	4	138
GO:0007507	heart development	1.27e-01	1.00e+00	2.890	1	7	139
GO:0006457	protein folding	1.30e-01	1.00e+00	2.849	1	7	143
GO:0008017	microtubule binding	1.34e-01	1.00e+00	2.809	1	2	147
GO:0001666	response to hypoxia	1.35e-01	1.00e+00	2.790	1	7	149
GO:0010467	gene expression	1.35e-01	1.00e+00	1.623	2	45	669
GO:0046777	protein autophosphorylation	1.43e-01	1.00e+00	2.705	1	4	158
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.49e-01	1.00e+00	2.642	1	12	165
GO:0038095	Fc-epsilon receptor signaling pathway	1.51e-01	1.00e+00	2.616	1	5	168
GO:0031625	ubiquitin protein ligase binding	1.60e-01	1.00e+00	2.533	1	5	178
GO:0032403	protein complex binding	1.64e-01	1.00e+00	2.493	1	6	183
GO:0006367	transcription initiation from RNA polymerase II promoter	1.65e-01	1.00e+00	2.485	1	22	184
GO:0003924	GTPase activity	1.75e-01	1.00e+00	2.387	1	7	197
GO:0006184	GTP catabolic process	1.89e-01	1.00e+00	2.267	1	7	214
GO:0019221	cytokine-mediated signaling pathway	1.94e-01	1.00e+00	2.221	1	8	221
GO:0016071	mRNA metabolic process	1.96e-01	1.00e+00	2.208	1	8	223
GO:0007067	mitotic nuclear division	1.99e-01	1.00e+00	2.182	1	6	227
GO:0007399	nervous system development	2.02e-01	1.00e+00	2.157	1	6	231
GO:0005730	nucleolus	2.08e-01	1.00e+00	0.913	3	66	1641
GO:0043025	neuronal cell body	2.13e-01	1.00e+00	2.072	1	9	245
GO:0016070	RNA metabolic process	2.15e-01	1.00e+00	2.060	1	8	247
GO:0005874	microtubule	2.16e-01	1.00e+00	2.049	1	7	249
GO:0007165	signal transduction	2.19e-01	1.00e+00	1.184	2	13	907
GO:0005975	carbohydrate metabolic process	2.20e-01	1.00e+00	2.026	1	8	253
GO:0006281	DNA repair	2.26e-01	1.00e+00	1.981	1	14	261
GO:0007283	spermatogenesis	2.26e-01	1.00e+00	1.975	1	3	262
GO:0043065	positive regulation of apoptotic process	2.31e-01	1.00e+00	1.943	1	7	268
GO:0048011	neurotrophin TRK receptor signaling pathway	2.32e-01	1.00e+00	1.937	1	7	269
GO:0030198	extracellular matrix organization	2.42e-01	1.00e+00	1.864	1	6	283
GO:0007186	G-protein coupled receptor signaling pathway	2.47e-01	1.00e+00	1.834	1	1	289
GO:0008270	zinc ion binding	2.52e-01	1.00e+00	1.047	2	27	997
GO:0030154	cell differentiation	2.56e-01	1.00e+00	1.775	1	5	301
GO:0035556	intracellular signal transduction	2.57e-01	1.00e+00	1.766	1	9	303
GO:0004674	protein serine/threonine kinase activity	2.61e-01	1.00e+00	1.742	1	6	308
GO:0005525	GTP binding	2.62e-01	1.00e+00	1.733	1	12	310
GO:0005813	centrosome	2.74e-01	1.00e+00	1.660	1	7	326
GO:0008283	cell proliferation	2.75e-01	1.00e+00	1.651	1	14	328
GO:0003723	RNA binding	2.85e-01	1.00e+00	1.591	1	18	342
GO:0008285	negative regulation of cell proliferation	2.93e-01	1.00e+00	1.545	1	10	353
GO:0007155	cell adhesion	3.04e-01	1.00e+00	1.481	1	5	369
GO:0046982	protein heterodimerization activity	3.12e-01	1.00e+00	1.439	1	8	380
GO:0009986	cell surface	3.27e-01	1.00e+00	1.358	1	9	402
GO:0045892	negative regulation of transcription, DNA-templated	3.34e-01	1.00e+00	1.319	1	24	413
GO:0055085	transmembrane transport	3.49e-01	1.00e+00	1.244	1	8	435
GO:0048471	perinuclear region of cytoplasm	3.91e-01	1.00e+00	1.037	1	8	502
GO:0005509	calcium ion binding	4.09e-01	1.00e+00	0.956	1	11	531
GO:0006351	transcription, DNA-templated	4.17e-01	1.00e+00	0.511	2	57	1446
GO:0070062	extracellular vesicular exosome	4.19e-01	1.00e+00	0.365	3	57	2400
GO:0005886	plasma membrane	4.71e-01	1.00e+00	0.259	3	49	2582
GO:0005739	mitochondrion	6.34e-01	1.00e+00	0.046	1	23	998
GO:0044281	small molecule metabolic process	7.07e-01	1.00e+00	-0.233	1	20	1211
GO:0005524	ATP binding	7.33e-01	1.00e+00	-0.333	1	31	1298
GO:0046872	metal ion binding	7.36e-01	1.00e+00	-0.343	1	29	1307
GO:0016020	membrane	8.24e-01	1.00e+00	-0.706	1	46	1681
GO:0016021	integral component of membrane	8.74e-01	1.00e+00	-0.944	1	17	1982

chia-Fav

int-snw-4790

Statistics

Genes (14)

Interactions (19)

Related GO terms (417)