int-snw-4286

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.805	3.45e-15	6.88e-04	4.35e-03

chia-screen-data-Fav-int-snw-4286 subnetwork

Genes (14)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
HCFC1	3054	40	-2.925	3.449	71	Yes	Yes
EP300	2033	22	-2.274	3.120	415	Yes	Yes
[ MITF ]	4286	1	-1.458	2.805	30	-	-
YAP1	10413	94	-4.256	3.538	53	Yes	-
NFRKB	4798	48	-3.129	3.108	23	Yes	Yes
SRSF3	6428	73	-2.992	3.538	54	Yes	-
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
HNRNPU	3192	76	-2.869	3.538	139	Yes	-
SPI1	6688	2	-2.003	2.870	115	Yes	Yes
MAPK14	1432	4	-1.902	2.955	272	-	-
SON	6651	9	-3.844	3.108	9	Yes	Yes
DDIT3	1649	60	-2.825	3.504	343	Yes	Yes
TFEB	7942	1	-1.953	2.805	4	-	-
SUMO1	7341	7	-1.696	3.050	439	-	-

Interactions (21)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
MAPK14	1432	MITF	4286	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
MAPK14	1432	DDIT3	1649	pp	--	int.I2D: BCI, BioGrid, HPRD; int.HPRD: in vitro
SON	6651	SUMO1	7341	pp	--	int.I2D: BioGrid
EP300	2033	MITF	4286	pp	--	int.I2D: HPRD; int.Ravasi: -; int.HPRD: in vitro, in vivo
HCFC1	3054	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
MITF	4286	SUMO1	7341	pp	--	int.I2D: BioGrid, HPRD; int.HPRD: in vitro, in vivo
DDIT3	1649	HNRNPU	3192	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
MITF	4286	SPI1	6688	pp	--	int.I2D: BioGrid, HPRD; int.Ravasi: -; int.HPRD: in vivo
HNRNPU	3192	SUMO1	7341	pp	--	int.I2D: BioGrid
POU5F1	5460	SPI1	6688	pp	--	int.Mysickova: lymph_node
MITF	4286	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
POU5F1	5460	SRSF3	6428	pp	--	int.I2D: BioGrid
HNRNPU	3192	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
DDIT3	1649	EP300	2033	pp	--	int.Intact: MI:0915(physical association)
EP300	2033	HNRNPU	3192	pp	--	int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vitro, in vivo
NFRKB	4798	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
HNRNPU	3192	YAP1	10413	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
POU5F1	5460	TFEB	7942	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
MITF	4286	TFEB	7942	pp	--	int.I2D: HPRD; int.Transfac: -; int.Ravasi: -; int.HPRD: in vivo
EP300	2033	YAP1	10413	pp	--	int.I2D: BioGrid
POU5F1	5460	SUMO1	7341	pp	--	int.I2D: BioGrid, BioGrid_Mouse

Related GO terms (339)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005654	nucleoplasm	1.03e-07	1.49e-03	3.099	9	64	1082
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	1.73e-07	2.50e-03	3.385	8	41	789
GO:0006355	regulation of transcription, DNA-templated	1.05e-06	1.51e-02	3.047	8	43	997
GO:0006366	transcription from RNA polymerase II promoter	1.43e-06	2.06e-02	3.883	6	30	419
GO:0051525	NFAT protein binding	8.74e-06	1.26e-01	8.687	2	2	5
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	9.42e-06	1.36e-01	6.134	3	4	44
GO:0044212	transcription regulatory region DNA binding	1.62e-05	2.34e-01	4.616	4	17	168
GO:0003700	sequence-specific DNA binding transcription factor activity	2.73e-05	3.93e-01	3.145	6	39	699
GO:0005634	nucleus	4.51e-05	6.50e-01	1.439	12	159	4559
GO:0042789	mRNA transcription from RNA polymerase II promoter	6.78e-05	9.78e-01	7.308	2	2	13
GO:0008134	transcription factor binding	6.78e-05	9.78e-01	4.090	4	18	242
GO:0005515	protein binding	1.00e-04	1.00e+00	1.153	13	198	6024
GO:0000123	histone acetyltransferase complex	1.82e-04	1.00e+00	6.616	2	6	21
GO:0030316	osteoclast differentiation	2.00e-04	1.00e+00	6.549	2	2	22
GO:0001205	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	2.00e-04	1.00e+00	6.549	2	4	22
GO:0003723	RNA binding	2.58e-04	1.00e+00	3.591	4	18	342
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	4.88e-04	1.00e+00	4.227	3	12	165
GO:0016607	nuclear speck	5.51e-04	1.00e+00	4.167	3	12	172
GO:0003677	DNA binding	5.94e-04	1.00e+00	2.343	6	49	1218
GO:0035019	somatic stem cell maintenance	6.68e-04	1.00e+00	5.687	2	6	40
GO:0007519	skeletal muscle tissue development	6.68e-04	1.00e+00	5.687	2	2	40
GO:0043966	histone H3 acetylation	8.46e-04	1.00e+00	5.517	2	5	45
GO:0001047	core promoter binding	8.46e-04	1.00e+00	5.517	2	5	45
GO:2000016	negative regulation of determination of dorsal identity	9.71e-04	1.00e+00	10.009	1	1	1
GO:1901985	positive regulation of protein acetylation	9.71e-04	1.00e+00	10.009	1	1	1
GO:0043969	histone H2B acetylation	9.71e-04	1.00e+00	10.009	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	9.71e-04	1.00e+00	10.009	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	9.71e-04	1.00e+00	10.009	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	9.71e-04	1.00e+00	10.009	1	1	1
GO:0060795	cell fate commitment involved in formation of primary germ layer	9.71e-04	1.00e+00	10.009	1	1	1
GO:0060177	regulation of angiotensin metabolic process	9.71e-04	1.00e+00	10.009	1	1	1
GO:0038066	p38MAPK cascade	9.71e-04	1.00e+00	10.009	1	1	1
GO:0014835	myoblast differentiation involved in skeletal muscle regeneration	9.71e-04	1.00e+00	10.009	1	1	1
GO:2000629	negative regulation of miRNA metabolic process	9.71e-04	1.00e+00	10.009	1	1	1
GO:0008380	RNA splicing	1.25e-03	1.00e+00	3.761	3	22	228
GO:0003713	transcription coactivator activity	1.39e-03	1.00e+00	3.705	3	24	237
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	1.45e-03	1.00e+00	5.126	2	6	59
GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	1.55e-03	1.00e+00	5.078	2	4	61
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	1.76e-03	1.00e+00	2.854	4	37	570
GO:0060242	contact inhibition	1.94e-03	1.00e+00	9.009	1	1	2
GO:0090241	negative regulation of histone H4 acetylation	1.94e-03	1.00e+00	9.009	1	2	2
GO:0019046	release from viral latency	1.94e-03	1.00e+00	9.009	1	2	2
GO:0090204	protein localization to nuclear pore	1.94e-03	1.00e+00	9.009	1	1	2
GO:0009786	regulation of asymmetric cell division	1.94e-03	1.00e+00	9.009	1	1	2
GO:0090043	regulation of tubulin deacetylation	1.94e-03	1.00e+00	9.009	1	2	2
GO:0071389	cellular response to mineralocorticoid stimulus	1.94e-03	1.00e+00	9.009	1	1	2
GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	1.94e-03	1.00e+00	9.009	1	1	2
GO:0014737	positive regulation of muscle atrophy	1.94e-03	1.00e+00	9.009	1	1	2
GO:0035984	cellular response to trichostatin A	1.94e-03	1.00e+00	9.009	1	1	2
GO:0044324	regulation of transcription involved in anterior/posterior axis specification	1.94e-03	1.00e+00	9.009	1	1	2
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	2.27e-03	1.00e+00	4.799	2	4	74
GO:0044822	poly(A) RNA binding	2.39e-03	1.00e+00	2.286	5	50	1056
GO:0018076	N-terminal peptidyl-lysine acetylation	2.91e-03	1.00e+00	8.424	1	1	3
GO:0060913	cardiac cell fate determination	2.91e-03	1.00e+00	8.424	1	1	3
GO:0001650	fibrillar center	2.91e-03	1.00e+00	8.424	1	1	3
GO:0010560	positive regulation of glycoprotein biosynthetic process	2.91e-03	1.00e+00	8.424	1	1	3
GO:0090400	stress-induced premature senescence	2.91e-03	1.00e+00	8.424	1	1	3
GO:0044027	hypermethylation of CpG island	2.91e-03	1.00e+00	8.424	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	2.91e-03	1.00e+00	8.424	1	1	3
GO:0090090	negative regulation of canonical Wnt signaling pathway	3.05e-03	1.00e+00	4.582	2	8	86
GO:0010467	gene expression	3.16e-03	1.00e+00	2.623	4	45	669
GO:0003682	chromatin binding	3.49e-03	1.00e+00	3.241	3	19	327
GO:0051726	regulation of cell cycle	3.86e-03	1.00e+00	4.409	2	5	97
GO:0097157	pre-mRNA intronic binding	3.88e-03	1.00e+00	8.009	1	1	4
GO:0030098	lymphocyte differentiation	3.88e-03	1.00e+00	8.009	1	1	4
GO:0030578	PML body organization	3.88e-03	1.00e+00	8.009	1	1	4
GO:0018393	internal peptidyl-lysine acetylation	3.88e-03	1.00e+00	8.009	1	1	4
GO:0045646	regulation of erythrocyte differentiation	3.88e-03	1.00e+00	8.009	1	1	4
GO:0070461	SAGA-type complex	4.84e-03	1.00e+00	7.687	1	2	5
GO:0001714	endodermal cell fate specification	4.84e-03	1.00e+00	7.687	1	1	5
GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process	4.84e-03	1.00e+00	7.687	1	2	5
GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	4.84e-03	1.00e+00	7.687	1	1	5
GO:0043620	regulation of DNA-templated transcription in response to stress	4.84e-03	1.00e+00	7.687	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	4.84e-03	1.00e+00	7.687	1	2	5
GO:0045347	negative regulation of MHC class II biosynthetic process	4.84e-03	1.00e+00	7.687	1	1	5
GO:0060033	anatomical structure regression	4.84e-03	1.00e+00	7.687	1	1	5
GO:0065004	protein-DNA complex assembly	4.84e-03	1.00e+00	7.687	1	1	5
GO:1901741	positive regulation of myoblast fusion	4.84e-03	1.00e+00	7.687	1	1	5
GO:0060298	positive regulation of sarcomere organization	4.84e-03	1.00e+00	7.687	1	1	5
GO:0032025	response to cobalt ion	4.84e-03	1.00e+00	7.687	1	1	5
GO:0046983	protein dimerization activity	5.66e-03	1.00e+00	4.126	2	5	118
GO:0006325	chromatin organization	5.66e-03	1.00e+00	4.126	2	12	118
GO:0050733	RS domain binding	5.81e-03	1.00e+00	7.424	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	5.81e-03	1.00e+00	7.424	1	3	6
GO:0002320	lymphoid progenitor cell differentiation	5.81e-03	1.00e+00	7.424	1	1	6
GO:1902262	apoptotic process involved in patterning of blood vessels	5.81e-03	1.00e+00	7.424	1	1	6
GO:0045892	negative regulation of transcription, DNA-templated	6.71e-03	1.00e+00	2.904	3	24	413
GO:0045814	negative regulation of gene expression, epigenetic	6.78e-03	1.00e+00	7.201	1	2	7
GO:0006475	internal protein amino acid acetylation	6.78e-03	1.00e+00	7.201	1	1	7
GO:0045670	regulation of osteoclast differentiation	7.74e-03	1.00e+00	7.009	1	2	8
GO:0001955	blood vessel maturation	7.74e-03	1.00e+00	7.009	1	1	8
GO:0070688	MLL5-L complex	7.74e-03	1.00e+00	7.009	1	1	8
GO:0043254	regulation of protein complex assembly	7.74e-03	1.00e+00	7.009	1	1	8
GO:0010831	positive regulation of myotube differentiation	7.74e-03	1.00e+00	7.009	1	1	8
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	8.66e-03	1.00e+00	3.809	2	6	147
GO:0035259	glucocorticoid receptor binding	8.70e-03	1.00e+00	6.839	1	1	9
GO:0045793	positive regulation of cell size	8.70e-03	1.00e+00	6.839	1	2	9
GO:0043996	histone acetyltransferase activity (H4-K8 specific)	8.70e-03	1.00e+00	6.839	1	5	9
GO:0043995	histone acetyltransferase activity (H4-K5 specific)	8.70e-03	1.00e+00	6.839	1	5	9
GO:0046972	histone acetyltransferase activity (H4-K16 specific)	8.70e-03	1.00e+00	6.839	1	5	9
GO:0060765	regulation of androgen receptor signaling pathway	8.70e-03	1.00e+00	6.839	1	1	9
GO:0048188	Set1C/COMPASS complex	8.70e-03	1.00e+00	6.839	1	4	9
GO:0006983	ER overload response	8.70e-03	1.00e+00	6.839	1	1	9
GO:0030851	granulocyte differentiation	8.70e-03	1.00e+00	6.839	1	1	9
GO:0032495	response to muramyl dipeptide	8.70e-03	1.00e+00	6.839	1	2	9
GO:0006974	cellular response to DNA damage stimulus	9.12e-03	1.00e+00	3.770	2	7	151
GO:0035413	positive regulation of catenin import into nucleus	9.67e-03	1.00e+00	6.687	1	2	10
GO:0016407	acetyltransferase activity	9.67e-03	1.00e+00	6.687	1	2	10
GO:0045893	positive regulation of transcription, DNA-templated	1.00e-02	1.00e+00	2.693	3	24	478
GO:0045663	positive regulation of myoblast differentiation	1.06e-02	1.00e+00	6.549	1	2	11
GO:0045662	negative regulation of myoblast differentiation	1.06e-02	1.00e+00	6.549	1	3	11
GO:0019395	fatty acid oxidation	1.06e-02	1.00e+00	6.549	1	2	11
GO:0004707	MAP kinase activity	1.06e-02	1.00e+00	6.549	1	1	11
GO:0043923	positive regulation by host of viral transcription	1.06e-02	1.00e+00	6.549	1	1	11
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	1.06e-02	1.00e+00	6.549	1	1	11
GO:0019789	SUMO ligase activity	1.06e-02	1.00e+00	6.549	1	1	11
GO:0033160	positive regulation of protein import into nucleus, translocation	1.06e-02	1.00e+00	6.549	1	3	11
GO:0042975	peroxisome proliferator activated receptor binding	1.06e-02	1.00e+00	6.549	1	1	11
GO:0042770	signal transduction in response to DNA damage	1.06e-02	1.00e+00	6.549	1	1	11
GO:0060391	positive regulation of SMAD protein import into nucleus	1.06e-02	1.00e+00	6.549	1	4	11
GO:0000398	mRNA splicing, via spliceosome	1.07e-02	1.00e+00	3.651	2	15	164
GO:0070935	3'-UTR-mediated mRNA stabilization	1.16e-02	1.00e+00	6.424	1	3	12
GO:0051146	striated muscle cell differentiation	1.16e-02	1.00e+00	6.424	1	1	12
GO:0035198	miRNA binding	1.16e-02	1.00e+00	6.424	1	1	12
GO:0005667	transcription factor complex	1.21e-02	1.00e+00	3.558	2	17	175
GO:0031625	ubiquitin protein ligase binding	1.25e-02	1.00e+00	3.533	2	5	178
GO:0003714	transcription corepressor activity	1.25e-02	1.00e+00	3.533	2	11	178
GO:0071480	cellular response to gamma radiation	1.26e-02	1.00e+00	6.308	1	1	13
GO:0004708	MAP kinase kinase activity	1.26e-02	1.00e+00	6.308	1	1	13
GO:0016746	transferase activity, transferring acyl groups	1.26e-02	1.00e+00	6.308	1	1	13
GO:0051019	mitogen-activated protein kinase binding	1.26e-02	1.00e+00	6.308	1	2	13
GO:0031334	positive regulation of protein complex assembly	1.26e-02	1.00e+00	6.308	1	2	13
GO:0005737	cytoplasm	1.35e-02	1.00e+00	1.130	8	124	3767
GO:0031011	Ino80 complex	1.35e-02	1.00e+00	6.201	1	6	14
GO:0070542	response to fatty acid	1.35e-02	1.00e+00	6.201	1	1	14
GO:0032993	protein-DNA complex	1.35e-02	1.00e+00	6.201	1	2	14
GO:0042307	positive regulation of protein import into nucleus	1.45e-02	1.00e+00	6.102	1	4	15
GO:0043011	myeloid dendritic cell differentiation	1.45e-02	1.00e+00	6.102	1	2	15
GO:0030225	macrophage differentiation	1.45e-02	1.00e+00	6.102	1	2	15
GO:0043981	histone H4-K5 acetylation	1.45e-02	1.00e+00	6.102	1	5	15
GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex	1.45e-02	1.00e+00	6.102	1	3	15
GO:0001824	blastocyst development	1.45e-02	1.00e+00	6.102	1	2	15
GO:0043982	histone H4-K8 acetylation	1.45e-02	1.00e+00	6.102	1	5	15
GO:0046849	bone remodeling	1.45e-02	1.00e+00	6.102	1	1	15
GO:1990090	cellular response to nerve growth factor stimulus	1.45e-02	1.00e+00	6.102	1	1	15
GO:0043274	phospholipase binding	1.54e-02	1.00e+00	6.009	1	1	16
GO:0060334	regulation of interferon-gamma-mediated signaling pathway	1.54e-02	1.00e+00	6.009	1	1	16
GO:0005730	nucleolus	1.57e-02	1.00e+00	1.650	5	66	1641
GO:0043536	positive regulation of blood vessel endothelial cell migration	1.64e-02	1.00e+00	5.921	1	3	17
GO:0045773	positive regulation of axon extension	1.73e-02	1.00e+00	5.839	1	1	18
GO:0033613	activating transcription factor binding	1.73e-02	1.00e+00	5.839	1	3	18
GO:0030318	melanocyte differentiation	1.83e-02	1.00e+00	5.761	1	3	19
GO:0043984	histone H4-K16 acetylation	1.83e-02	1.00e+00	5.761	1	5	19
GO:0001227	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	1.83e-02	1.00e+00	5.761	1	2	19
GO:0035257	nuclear hormone receptor binding	1.83e-02	1.00e+00	5.761	1	1	19
GO:0071549	cellular response to dexamethasone stimulus	1.92e-02	1.00e+00	5.687	1	3	20
GO:0048010	vascular endothelial growth factor receptor signaling pathway	1.92e-02	1.00e+00	5.687	1	1	20
GO:0010942	positive regulation of cell death	1.92e-02	1.00e+00	5.687	1	1	20
GO:0001502	cartilage condensation	1.92e-02	1.00e+00	5.687	1	1	20
GO:0032757	positive regulation of interleukin-8 production	1.92e-02	1.00e+00	5.687	1	1	20
GO:0035924	cellular response to vascular endothelial growth factor stimulus	1.92e-02	1.00e+00	5.687	1	1	20
GO:0051090	regulation of sequence-specific DNA binding transcription factor activity	1.92e-02	1.00e+00	5.687	1	3	20
GO:0045648	positive regulation of erythrocyte differentiation	2.02e-02	1.00e+00	5.616	1	1	21
GO:0032967	positive regulation of collagen biosynthetic process	2.02e-02	1.00e+00	5.616	1	3	21
GO:0045862	positive regulation of proteolysis	2.02e-02	1.00e+00	5.616	1	2	21
GO:0003823	antigen binding	2.12e-02	1.00e+00	5.549	1	2	22
GO:0043484	regulation of RNA splicing	2.12e-02	1.00e+00	5.549	1	1	22
GO:0010508	positive regulation of autophagy	2.12e-02	1.00e+00	5.549	1	2	22
GO:0045787	positive regulation of cell cycle	2.12e-02	1.00e+00	5.549	1	2	22
GO:0036464	cytoplasmic ribonucleoprotein granule	2.12e-02	1.00e+00	5.549	1	2	22
GO:0001892	embryonic placenta development	2.21e-02	1.00e+00	5.485	1	1	23
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	2.21e-02	1.00e+00	5.485	1	1	23
GO:0071479	cellular response to ionizing radiation	2.21e-02	1.00e+00	5.485	1	1	23
GO:2000379	positive regulation of reactive oxygen species metabolic process	2.21e-02	1.00e+00	5.485	1	2	23
GO:0043388	positive regulation of DNA binding	2.31e-02	1.00e+00	5.424	1	2	24
GO:0043425	bHLH transcription factor binding	2.31e-02	1.00e+00	5.424	1	1	24
GO:0016925	protein sumoylation	2.40e-02	1.00e+00	5.365	1	2	25
GO:0051059	NF-kappaB binding	2.40e-02	1.00e+00	5.365	1	3	25
GO:0035329	hippo signaling	2.50e-02	1.00e+00	5.308	1	5	26
GO:0007040	lysosome organization	2.50e-02	1.00e+00	5.308	1	1	26
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	2.50e-02	1.00e+00	5.308	1	1	26
GO:0043392	negative regulation of DNA binding	2.50e-02	1.00e+00	5.308	1	4	26
GO:0051209	release of sequestered calcium ion into cytosol	2.50e-02	1.00e+00	5.308	1	1	26
GO:0048565	digestive tract development	2.50e-02	1.00e+00	5.308	1	2	26
GO:0006281	DNA repair	2.57e-02	1.00e+00	2.981	2	14	261
GO:0051149	positive regulation of muscle cell differentiation	2.59e-02	1.00e+00	5.254	1	4	27
GO:0000077	DNA damage checkpoint	2.59e-02	1.00e+00	5.254	1	1	27
GO:0034612	response to tumor necrosis factor	2.59e-02	1.00e+00	5.254	1	2	27
GO:0071339	MLL1 complex	2.59e-02	1.00e+00	5.254	1	6	27
GO:0043967	histone H4 acetylation	2.59e-02	1.00e+00	5.254	1	1	27
GO:0006357	regulation of transcription from RNA polymerase II promoter	2.63e-02	1.00e+00	2.964	2	23	264
GO:0050714	positive regulation of protein secretion	2.69e-02	1.00e+00	5.201	1	3	28
GO:0031663	lipopolysaccharide-mediated signaling pathway	2.78e-02	1.00e+00	5.151	1	2	29
GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	2.87e-02	1.00e+00	5.102	1	1	30
GO:0042594	response to starvation	2.97e-02	1.00e+00	5.055	1	4	31
GO:0043491	protein kinase B signaling	3.06e-02	1.00e+00	5.009	1	2	32
GO:0002062	chondrocyte differentiation	3.06e-02	1.00e+00	5.009	1	2	32
GO:1903507	negative regulation of nucleic acid-templated transcription	3.06e-02	1.00e+00	5.009	1	2	32
GO:0001756	somitogenesis	3.16e-02	1.00e+00	4.964	1	1	33
GO:0071333	cellular response to glucose stimulus	3.16e-02	1.00e+00	4.964	1	1	33
GO:0001085	RNA polymerase II transcription factor binding	3.16e-02	1.00e+00	4.964	1	2	33
GO:0042692	muscle cell differentiation	3.25e-02	1.00e+00	4.921	1	4	34
GO:0043010	camera-type eye development	3.25e-02	1.00e+00	4.921	1	1	34
GO:0001102	RNA polymerase II activating transcription factor binding	3.44e-02	1.00e+00	4.839	1	1	36
GO:0030218	erythrocyte differentiation	3.53e-02	1.00e+00	4.799	1	1	37
GO:0032880	regulation of protein localization	3.53e-02	1.00e+00	4.799	1	2	37
GO:0031490	chromatin DNA binding	3.63e-02	1.00e+00	4.761	1	2	38
GO:0032092	positive regulation of protein binding	3.63e-02	1.00e+00	4.761	1	2	38
GO:0050681	androgen receptor binding	3.63e-02	1.00e+00	4.761	1	1	38
GO:0046332	SMAD binding	3.82e-02	1.00e+00	4.687	1	2	40
GO:0071320	cellular response to cAMP	3.82e-02	1.00e+00	4.687	1	1	40
GO:0070301	cellular response to hydrogen peroxide	3.91e-02	1.00e+00	4.651	1	2	41
GO:0031124	mRNA 3'-end processing	4.00e-02	1.00e+00	4.616	1	2	42
GO:0004402	histone acetyltransferase activity	4.10e-02	1.00e+00	4.582	1	6	43
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	4.19e-02	1.00e+00	4.549	1	3	44
GO:0045165	cell fate commitment	4.19e-02	1.00e+00	4.549	1	1	44
GO:0045727	positive regulation of translation	4.19e-02	1.00e+00	4.549	1	2	44
GO:0006369	termination of RNA polymerase II transcription	4.28e-02	1.00e+00	4.517	1	2	45
GO:0043565	sequence-specific DNA binding	4.32e-02	1.00e+00	2.574	2	11	346
GO:0043525	positive regulation of neuron apoptotic process	4.38e-02	1.00e+00	4.485	1	4	46
GO:0006959	humoral immune response	4.47e-02	1.00e+00	4.454	1	3	47
GO:0000902	cell morphogenesis	4.65e-02	1.00e+00	4.394	1	4	49
GO:0035690	cellular response to drug	4.65e-02	1.00e+00	4.394	1	3	49
GO:0006986	response to unfolded protein	4.75e-02	1.00e+00	4.365	1	4	50
GO:0034976	response to endoplasmic reticulum stress	4.84e-02	1.00e+00	4.336	1	2	51
GO:0045454	cell redox homeostasis	4.84e-02	1.00e+00	4.336	1	1	51
GO:0000910	cytokinesis	4.84e-02	1.00e+00	4.336	1	2	51
GO:0000226	microtubule cytoskeleton organization	4.93e-02	1.00e+00	4.308	1	2	52
GO:0009611	response to wounding	4.93e-02	1.00e+00	4.308	1	5	52
GO:0007623	circadian rhythm	5.03e-02	1.00e+00	4.281	1	1	53
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	5.03e-02	1.00e+00	4.281	1	5	53
GO:0051403	stress-activated MAPK cascade	5.12e-02	1.00e+00	4.254	1	2	54
GO:0051592	response to calcium ion	5.21e-02	1.00e+00	4.227	1	1	55
GO:0002039	p53 binding	5.21e-02	1.00e+00	4.227	1	4	55
GO:0071300	cellular response to retinoic acid	5.21e-02	1.00e+00	4.227	1	1	55
GO:0043627	response to estrogen	5.30e-02	1.00e+00	4.201	1	5	56
GO:0005643	nuclear pore	5.40e-02	1.00e+00	4.176	1	11	57
GO:0006396	RNA processing	5.58e-02	1.00e+00	4.126	1	5	59
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	5.58e-02	1.00e+00	4.126	1	5	59
GO:0008013	beta-catenin binding	5.67e-02	1.00e+00	4.102	1	9	60
GO:0006987	activation of signaling protein activity involved in unfolded protein response	5.76e-02	1.00e+00	4.078	1	2	61
GO:0032481	positive regulation of type I interferon production	5.76e-02	1.00e+00	4.078	1	6	61
GO:0006406	mRNA export from nucleus	5.76e-02	1.00e+00	4.078	1	4	61
GO:0060333	interferon-gamma-mediated signaling pathway	5.86e-02	1.00e+00	4.055	1	3	62
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	5.95e-02	1.00e+00	4.031	1	4	63
GO:0006310	DNA recombination	6.13e-02	1.00e+00	3.986	1	7	65
GO:0034166	toll-like receptor 10 signaling pathway	6.13e-02	1.00e+00	3.986	1	4	65
GO:0034146	toll-like receptor 5 signaling pathway	6.13e-02	1.00e+00	3.986	1	4	65
GO:0010468	regulation of gene expression	6.40e-02	1.00e+00	3.921	1	2	68
GO:0018105	peptidyl-serine phosphorylation	6.50e-02	1.00e+00	3.900	1	2	69
GO:0038123	toll-like receptor TLR1:TLR2 signaling pathway	6.68e-02	1.00e+00	3.859	1	4	71
GO:0038124	toll-like receptor TLR6:TLR2 signaling pathway	6.68e-02	1.00e+00	3.859	1	4	71
GO:0060021	palate development	6.77e-02	1.00e+00	3.839	1	1	72
GO:0034162	toll-like receptor 9 signaling pathway	6.77e-02	1.00e+00	3.839	1	4	72
GO:0030324	lung development	6.77e-02	1.00e+00	3.839	1	1	72
GO:0034134	toll-like receptor 2 signaling pathway	6.86e-02	1.00e+00	3.819	1	4	73
GO:0000785	chromatin	6.86e-02	1.00e+00	3.819	1	6	73
GO:0006914	autophagy	6.95e-02	1.00e+00	3.799	1	3	74
GO:0002020	protease binding	6.95e-02	1.00e+00	3.799	1	6	74
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	7.04e-02	1.00e+00	3.780	1	1	75
GO:0007265	Ras protein signal transduction	7.04e-02	1.00e+00	3.780	1	3	75
GO:0035666	TRIF-dependent toll-like receptor signaling pathway	7.13e-02	1.00e+00	3.761	1	3	76
GO:0001889	liver development	7.22e-02	1.00e+00	3.742	1	3	77
GO:0071013	catalytic step 2 spliceosome	7.31e-02	1.00e+00	3.723	1	7	78
GO:0002756	MyD88-independent toll-like receptor signaling pathway	7.31e-02	1.00e+00	3.723	1	3	78
GO:0034138	toll-like receptor 3 signaling pathway	7.40e-02	1.00e+00	3.705	1	3	79
GO:0030968	endoplasmic reticulum unfolded protein response	7.40e-02	1.00e+00	3.705	1	2	79
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	7.49e-02	1.00e+00	3.687	1	5	80
GO:0044267	cellular protein metabolic process	7.56e-02	1.00e+00	2.120	2	20	474
GO:0071222	cellular response to lipopolysaccharide	7.59e-02	1.00e+00	3.669	1	4	81
GO:0009653	anatomical structure morphogenesis	7.77e-02	1.00e+00	3.634	1	2	83
GO:0009887	organ morphogenesis	8.04e-02	1.00e+00	3.582	1	5	86
GO:0045471	response to ethanol	8.04e-02	1.00e+00	3.582	1	3	86
GO:0000922	spindle pole	8.13e-02	1.00e+00	3.566	1	4	87
GO:0050821	protein stabilization	8.21e-02	1.00e+00	3.549	1	3	88
GO:0016605	PML body	8.21e-02	1.00e+00	3.549	1	3	88
GO:0000187	activation of MAPK activity	8.39e-02	1.00e+00	3.517	1	3	90
GO:0006928	cellular component movement	8.48e-02	1.00e+00	3.501	1	3	91
GO:0001649	osteoblast differentiation	8.57e-02	1.00e+00	3.485	1	5	92
GO:0071456	cellular response to hypoxia	8.57e-02	1.00e+00	3.485	1	3	92
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	8.57e-02	1.00e+00	3.485	1	7	92
GO:0005770	late endosome	8.66e-02	1.00e+00	3.470	1	2	93
GO:0034142	toll-like receptor 4 signaling pathway	8.93e-02	1.00e+00	3.424	1	4	96
GO:0001934	positive regulation of protein phosphorylation	9.64e-02	1.00e+00	3.308	1	5	104
GO:0006935	chemotaxis	9.73e-02	1.00e+00	3.294	1	3	105
GO:0003676	nucleic acid binding	9.90e-02	1.00e+00	3.267	1	2	107
GO:0006915	apoptotic process	9.91e-02	1.00e+00	1.892	2	12	555
GO:0042127	regulation of cell proliferation	1.01e-01	1.00e+00	3.241	1	4	109
GO:0002224	toll-like receptor signaling pathway	1.01e-01	1.00e+00	3.241	1	4	109
GO:0030529	ribonucleoprotein complex	1.03e-01	1.00e+00	3.201	1	5	112
GO:0006461	protein complex assembly	1.03e-01	1.00e+00	3.214	1	4	111
GO:0006006	glucose metabolic process	1.09e-01	1.00e+00	3.126	1	5	118
GO:0007219	Notch signaling pathway	1.10e-01	1.00e+00	3.102	1	5	120
GO:0045087	innate immune response	1.12e-01	1.00e+00	1.790	2	15	596
GO:0007050	cell cycle arrest	1.14e-01	1.00e+00	3.055	1	5	124
GO:0000790	nuclear chromatin	1.18e-01	1.00e+00	2.998	1	6	129
GO:0000086	G2/M transition of mitotic cell cycle	1.24e-01	1.00e+00	2.921	1	4	136
GO:0045202	synapse	1.24e-01	1.00e+00	2.921	1	5	136
GO:0016055	Wnt signaling pathway	1.26e-01	1.00e+00	2.900	1	4	138
GO:0007507	heart development	1.27e-01	1.00e+00	2.890	1	7	139
GO:0010628	positive regulation of gene expression	1.33e-01	1.00e+00	2.819	1	7	146
GO:0007166	cell surface receptor signaling pathway	1.34e-01	1.00e+00	2.809	1	4	147
GO:0001666	response to hypoxia	1.35e-01	1.00e+00	2.790	1	7	149
GO:0006397	mRNA processing	1.45e-01	1.00e+00	2.687	1	10	160
GO:0043687	post-translational protein modification	1.46e-01	1.00e+00	2.669	1	5	162
GO:0031965	nuclear membrane	1.51e-01	1.00e+00	2.616	1	10	168
GO:0007049	cell cycle	1.56e-01	1.00e+00	2.566	1	6	174
GO:0006351	transcription, DNA-templated	1.59e-01	1.00e+00	1.096	3	57	1446
GO:0032403	protein complex binding	1.64e-01	1.00e+00	2.493	1	6	183
GO:0006367	transcription initiation from RNA polymerase II promoter	1.65e-01	1.00e+00	2.485	1	22	184
GO:0001525	angiogenesis	1.70e-01	1.00e+00	2.431	1	7	191
GO:0030168	platelet activation	1.82e-01	1.00e+00	2.329	1	6	205
GO:0019221	cytokine-mediated signaling pathway	1.94e-01	1.00e+00	2.221	1	8	221
GO:0016071	mRNA metabolic process	1.96e-01	1.00e+00	2.208	1	8	223
GO:0030425	dendrite	2.02e-01	1.00e+00	2.163	1	6	230
GO:0007399	nervous system development	2.02e-01	1.00e+00	2.157	1	6	231
GO:0005829	cytosol	2.13e-01	1.00e+00	0.723	4	86	2496
GO:0043025	neuronal cell body	2.13e-01	1.00e+00	2.072	1	9	245
GO:0016070	RNA metabolic process	2.15e-01	1.00e+00	2.060	1	8	247
GO:0000166	nucleotide binding	2.24e-01	1.00e+00	1.992	1	13	259
GO:0048011	neurotrophin TRK receptor signaling pathway	2.32e-01	1.00e+00	1.937	1	7	269
GO:0006954	inflammatory response	2.38e-01	1.00e+00	1.895	1	6	277
GO:0043234	protein complex	2.51e-01	1.00e+00	1.804	1	11	295
GO:0005739	mitochondrion	2.52e-01	1.00e+00	1.046	2	23	998
GO:0035556	intracellular signal transduction	2.57e-01	1.00e+00	1.766	1	9	303
GO:0004674	protein serine/threonine kinase activity	2.61e-01	1.00e+00	1.742	1	6	308
GO:0008283	cell proliferation	2.75e-01	1.00e+00	1.651	1	14	328
GO:0046982	protein heterodimerization activity	3.12e-01	1.00e+00	1.439	1	8	380
GO:0000278	mitotic cell cycle	3.20e-01	1.00e+00	1.398	1	15	391
GO:0009986	cell surface	3.27e-01	1.00e+00	1.358	1	9	402
GO:0043066	negative regulation of apoptotic process	3.42e-01	1.00e+00	1.281	1	16	424
GO:0007596	blood coagulation	3.62e-01	1.00e+00	1.179	1	11	455
GO:0005524	ATP binding	3.63e-01	1.00e+00	0.667	2	31	1298
GO:0042802	identical protein binding	3.80e-01	1.00e+00	1.090	1	19	484
GO:0016032	viral process	4.10e-01	1.00e+00	0.948	1	26	534
GO:0016020	membrane	4.98e-01	1.00e+00	0.294	2	46	1681
GO:0007165	signal transduction	5.97e-01	1.00e+00	0.184	1	13	907
GO:0008270	zinc ion binding	6.33e-01	1.00e+00	0.047	1	27	997
GO:0070062	extracellular vesicular exosome	9.22e-01	1.00e+00	-1.220	1	57	2400

chia-Fav

int-snw-4286

Statistics

Genes (14)

Interactions (21)

Related GO terms (339)