Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
chia-screen-data-Fav | 2.949 | 9.43e-17 | 1.16e-04 | 1.23e-03 |
Gene Symbol | Entrez Gene ID | Frequency | chia-screen-data-Fav gene score | Best subnetwork score | Degree | Chia-Hits Primary | Chia-Hits Secondary |
---|---|---|---|---|---|---|---|
EP300 | 2033 | 22 | -2.274 | 3.120 | 415 | Yes | Yes |
PSMD2 | 5708 | 47 | -4.172 | 3.157 | 386 | Yes | Yes |
TCP1 | 6950 | 10 | -2.383 | 3.119 | 241 | Yes | - |
HES6 | 55502 | 8 | -2.557 | 3.120 | 11 | Yes | Yes |
YAP1 | 10413 | 94 | -4.256 | 3.538 | 53 | Yes | - |
TCL1A | 8115 | 8 | -2.457 | 3.120 | 11 | Yes | Yes |
[ DBP ] | 1628 | 1 | -1.447 | 2.949 | 26 | - | - |
POU5F1 | 5460 | 133 | -5.148 | 3.538 | 179 | Yes | Yes |
HNRNPU | 3192 | 76 | -2.869 | 3.538 | 139 | Yes | - |
YY1 | 7528 | 24 | -2.572 | 3.120 | 114 | Yes | Yes |
DDIT3 | 1649 | 60 | -2.825 | 3.504 | 343 | Yes | Yes |
H1FX | 8971 | 7 | -2.421 | 3.504 | 35 | Yes | Yes |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
EP300 | 2033 | HNRNPU | 3192 | pp | -- | int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vitro, in vivo |
EP300 | 2033 | YY1 | 7528 | pp | -- | int.I2D: BioGrid, BCI, HPRD; int.Transfac: -; int.Ravasi: -; int.HPRD: in vivo; int.DIP: MI:0218(physical interaction) |
EP300 | 2033 | TCL1A | 8115 | pp | -- | int.I2D: INNATEDB |
DDIT3 | 1649 | TCP1 | 6950 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
DBP | 1628 | DDIT3 | 1649 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BEHRENDS_AUTOPHAGY_LOW, BIND; int.Transfac: - |
DDIT3 | 1649 | H1FX | 8971 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
HNRNPU | 3192 | YAP1 | 10413 | pp | -- | int.I2D: HPRD; int.HPRD: in vitro, in vivo |
DDIT3 | 1649 | HNRNPU | 3192 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
PSMD2 | 5708 | TCP1 | 6950 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow |
DBP | 1628 | EP300 | 2033 | pp | -- | int.I2D: BCI, HPRD; int.Ravasi: -; int.HPRD: in vitro, in vivo |
EP300 | 2033 | HES6 | 55502 | pp | -- | int.I2D: IntAct |
DDIT3 | 1649 | EP300 | 2033 | pp | -- | int.Intact: MI:0915(physical association) |
HNRNPU | 3192 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
EP300 | 2033 | YAP1 | 10413 | pp | -- | int.I2D: BioGrid |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0044212 | transcription regulatory region DNA binding | 8.17e-06 | 1.18e-01 | 4.839 | 4 | 17 | 168 |
GO:0005667 | transcription factor complex | 9.61e-06 | 1.39e-01 | 4.780 | 4 | 17 | 175 |
GO:0003677 | DNA binding | 1.63e-05 | 2.35e-01 | 2.788 | 7 | 49 | 1218 |
GO:0008134 | transcription factor binding | 3.44e-05 | 4.97e-01 | 4.312 | 4 | 18 | 242 |
GO:0042789 | mRNA transcription from RNA polymerase II promoter | 4.92e-05 | 7.10e-01 | 7.531 | 2 | 2 | 13 |
GO:0005654 | nucleoplasm | 1.10e-04 | 1.00e+00 | 2.737 | 6 | 64 | 1082 |
GO:0003700 | sequence-specific DNA binding transcription factor activity | 1.57e-04 | 1.00e+00 | 3.104 | 5 | 39 | 699 |
GO:0006974 | cellular response to DNA damage stimulus | 2.31e-04 | 1.00e+00 | 4.578 | 3 | 7 | 151 |
GO:0003714 | transcription corepressor activity | 3.75e-04 | 1.00e+00 | 4.340 | 3 | 11 | 178 |
GO:0006355 | regulation of transcription, DNA-templated | 8.21e-04 | 1.00e+00 | 2.592 | 5 | 43 | 997 |
GO:0060795 | cell fate commitment involved in formation of primary germ layer | 8.32e-04 | 1.00e+00 | 10.231 | 1 | 1 | 1 |
GO:0060177 | regulation of angiotensin metabolic process | 8.32e-04 | 1.00e+00 | 10.231 | 1 | 1 | 1 |
GO:1901985 | positive regulation of protein acetylation | 8.32e-04 | 1.00e+00 | 10.231 | 1 | 1 | 1 |
GO:2000016 | negative regulation of determination of dorsal identity | 8.32e-04 | 1.00e+00 | 10.231 | 1 | 1 | 1 |
GO:0043969 | histone H2B acetylation | 8.32e-04 | 1.00e+00 | 10.231 | 1 | 1 | 1 |
GO:2000629 | negative regulation of miRNA metabolic process | 8.32e-04 | 1.00e+00 | 10.231 | 1 | 1 | 1 |
GO:0090308 | regulation of methylation-dependent chromatin silencing | 8.32e-04 | 1.00e+00 | 10.231 | 1 | 1 | 1 |
GO:0090081 | regulation of heart induction by regulation of canonical Wnt signaling pathway | 8.32e-04 | 1.00e+00 | 10.231 | 1 | 1 | 1 |
GO:0060965 | negative regulation of gene silencing by miRNA | 8.32e-04 | 1.00e+00 | 10.231 | 1 | 1 | 1 |
GO:0003713 | transcription coactivator activity | 8.64e-04 | 1.00e+00 | 3.927 | 3 | 24 | 237 |
GO:0006357 | regulation of transcription from RNA polymerase II promoter | 1.18e-03 | 1.00e+00 | 3.772 | 3 | 23 | 264 |
GO:0034696 | response to prostaglandin F | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0060242 | contact inhibition | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0014737 | positive regulation of muscle atrophy | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0006403 | RNA localization | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0009786 | regulation of asymmetric cell division | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0090043 | regulation of tubulin deacetylation | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 2 | 2 |
GO:0035984 | cellular response to trichostatin A | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0071389 | cellular response to mineralocorticoid stimulus | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0044324 | regulation of transcription involved in anterior/posterior axis specification | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0001889 | liver development | 1.79e-03 | 1.00e+00 | 4.964 | 2 | 3 | 77 |
GO:0018076 | N-terminal peptidyl-lysine acetylation | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 3 |
GO:0060913 | cardiac cell fate determination | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 3 |
GO:0003130 | BMP signaling pathway involved in heart induction | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 3 |
GO:0010560 | positive regulation of glycoprotein biosynthetic process | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 3 |
GO:0005634 | nucleus | 2.54e-03 | 1.00e+00 | 1.247 | 9 | 159 | 4559 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 3.09e-03 | 1.00e+00 | 2.607 | 4 | 41 | 789 |
GO:0007021 | tubulin complex assembly | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0097157 | pre-mRNA intronic binding | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0018393 | internal peptidyl-lysine acetylation | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0001714 | endodermal cell fate specification | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0065004 | protein-DNA complex assembly | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0043620 | regulation of DNA-templated transcription in response to stress | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0070934 | CRD-mediated mRNA stabilization | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 2 | 5 |
GO:0060298 | positive regulation of sarcomere organization | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0032025 | response to cobalt ion | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0070937 | CRD-mediated mRNA stability complex | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 3 | 6 |
GO:0006475 | internal protein amino acid acetylation | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 1 | 7 |
GO:0001955 | blood vessel maturation | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 1 | 8 |
GO:0060765 | regulation of androgen receptor signaling pathway | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 9 |
GO:0010225 | response to UV-C | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 2 | 9 |
GO:0006983 | ER overload response | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 9 |
GO:0035259 | glucocorticoid receptor binding | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 9 |
GO:0045793 | positive regulation of cell size | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 2 | 9 |
GO:0000400 | four-way junction DNA binding | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 9 |
GO:0005832 | chaperonin-containing T-complex | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 2 | 9 |
GO:0002199 | zona pellucida receptor complex | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 2 | 10 |
GO:0035413 | positive regulation of catenin import into nucleus | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 2 | 10 |
GO:0016407 | acetyltransferase activity | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 2 | 10 |
GO:0044822 | poly(A) RNA binding | 8.79e-03 | 1.00e+00 | 2.187 | 4 | 50 | 1056 |
GO:0043923 | positive regulation by host of viral transcription | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 1 | 11 |
GO:0033160 | positive regulation of protein import into nucleus, translocation | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 3 | 11 |
GO:0045662 | negative regulation of myoblast differentiation | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 3 | 11 |
GO:0042975 | peroxisome proliferator activated receptor binding | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 1 | 11 |
GO:0045120 | pronucleus | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 2 | 11 |
GO:0060391 | positive regulation of SMAD protein import into nucleus | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 4 | 11 |
GO:0005838 | proteasome regulatory particle | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 12 |
GO:0035198 | miRNA binding | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 12 |
GO:0071480 | cellular response to gamma radiation | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 1 | 13 |
GO:0051019 | mitogen-activated protein kinase binding | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 2 | 13 |
GO:0016746 | transferase activity, transferring acyl groups | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 1 | 13 |
GO:0030234 | enzyme regulator activity | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 2 | 13 |
GO:0070542 | response to fatty acid | 1.16e-02 | 1.00e+00 | 6.424 | 1 | 1 | 14 |
GO:0031011 | Ino80 complex | 1.16e-02 | 1.00e+00 | 6.424 | 1 | 6 | 14 |
GO:0000242 | pericentriolar material | 1.16e-02 | 1.00e+00 | 6.424 | 1 | 1 | 14 |
GO:0032993 | protein-DNA complex | 1.16e-02 | 1.00e+00 | 6.424 | 1 | 2 | 14 |
GO:0001824 | blastocyst development | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 2 | 15 |
GO:1990090 | cellular response to nerve growth factor stimulus | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 1 | 15 |
GO:0042176 | regulation of protein catabolic process | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 2 | 16 |
GO:0051276 | chromosome organization | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 2 | 16 |
GO:0048593 | camera-type eye morphogenesis | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 1 | 16 |
GO:0022624 | proteasome accessory complex | 1.41e-02 | 1.00e+00 | 6.144 | 1 | 1 | 17 |
GO:0045773 | positive regulation of axon extension | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 1 | 18 |
GO:0033613 | activating transcription factor binding | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 3 | 18 |
GO:0007399 | nervous system development | 1.52e-02 | 1.00e+00 | 3.379 | 2 | 6 | 231 |
GO:0035257 | nuclear hormone receptor binding | 1.57e-02 | 1.00e+00 | 5.983 | 1 | 1 | 19 |
GO:0010467 | gene expression | 1.60e-02 | 1.00e+00 | 2.430 | 3 | 45 | 669 |
GO:0071549 | cellular response to dexamethasone stimulus | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 3 | 20 |
GO:0010942 | positive regulation of cell death | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 1 | 20 |
GO:0032757 | positive regulation of interleukin-8 production | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 1 | 20 |
GO:0000123 | histone acetyltransferase complex | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 6 | 21 |
GO:0032967 | positive regulation of collagen biosynthetic process | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 3 | 21 |
GO:0045862 | positive regulation of proteolysis | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 2 | 21 |
GO:0003823 | antigen binding | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 2 | 22 |
GO:0005720 | nuclear heterochromatin | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 2 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 2 | 22 |
GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 1 | 23 |
GO:0043388 | positive regulation of DNA binding | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 2 | 24 |
GO:0043425 | bHLH transcription factor binding | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 1 | 24 |
GO:0051059 | NF-kappaB binding | 2.06e-02 | 1.00e+00 | 5.587 | 1 | 3 | 25 |
GO:0007339 | binding of sperm to zona pellucida | 2.06e-02 | 1.00e+00 | 5.587 | 1 | 2 | 25 |
GO:0031519 | PcG protein complex | 2.06e-02 | 1.00e+00 | 5.587 | 1 | 1 | 25 |
GO:0005515 | protein binding | 2.09e-02 | 1.00e+00 | 0.845 | 9 | 198 | 6024 |
GO:0035329 | hippo signaling | 2.14e-02 | 1.00e+00 | 5.531 | 1 | 5 | 26 |
GO:0051209 | release of sequestered calcium ion into cytosol | 2.14e-02 | 1.00e+00 | 5.531 | 1 | 1 | 26 |
GO:0048565 | digestive tract development | 2.14e-02 | 1.00e+00 | 5.531 | 1 | 2 | 26 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 2.14e-02 | 1.00e+00 | 5.531 | 1 | 1 | 26 |
GO:0034612 | response to tumor necrosis factor | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 2 | 27 |
GO:0043967 | histone H4 acetylation | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 1 | 27 |
GO:0050714 | positive regulation of protein secretion | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 3 | 28 |
GO:0034644 | cellular response to UV | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 1 | 30 |
GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 1 | 30 |
GO:0030154 | cell differentiation | 2.50e-02 | 1.00e+00 | 2.998 | 2 | 5 | 301 |
GO:0042594 | response to starvation | 2.55e-02 | 1.00e+00 | 5.277 | 1 | 4 | 31 |
GO:0006351 | transcription, DNA-templated | 2.58e-02 | 1.00e+00 | 1.733 | 4 | 57 | 1446 |
GO:0043491 | protein kinase B signaling | 2.63e-02 | 1.00e+00 | 5.231 | 1 | 2 | 32 |
GO:1903507 | negative regulation of nucleic acid-templated transcription | 2.63e-02 | 1.00e+00 | 5.231 | 1 | 2 | 32 |
GO:0071333 | cellular response to glucose stimulus | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 1 | 33 |
GO:0001756 | somitogenesis | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 1 | 33 |
GO:0001102 | RNA polymerase II activating transcription factor binding | 2.96e-02 | 1.00e+00 | 5.061 | 1 | 1 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 3.04e-02 | 1.00e+00 | 5.022 | 1 | 5 | 37 |
GO:0032092 | positive regulation of protein binding | 3.12e-02 | 1.00e+00 | 4.983 | 1 | 2 | 38 |
GO:0031490 | chromatin DNA binding | 3.12e-02 | 1.00e+00 | 4.983 | 1 | 2 | 38 |
GO:0050681 | androgen receptor binding | 3.12e-02 | 1.00e+00 | 4.983 | 1 | 1 | 38 |
GO:0003723 | RNA binding | 3.16e-02 | 1.00e+00 | 2.813 | 2 | 18 | 342 |
GO:0043565 | sequence-specific DNA binding | 3.23e-02 | 1.00e+00 | 2.796 | 2 | 11 | 346 |
GO:0035019 | somatic stem cell maintenance | 3.28e-02 | 1.00e+00 | 4.909 | 1 | 6 | 40 |
GO:0007519 | skeletal muscle tissue development | 3.28e-02 | 1.00e+00 | 4.909 | 1 | 2 | 40 |
GO:0046332 | SMAD binding | 3.28e-02 | 1.00e+00 | 4.909 | 1 | 2 | 40 |
GO:0071320 | cellular response to cAMP | 3.28e-02 | 1.00e+00 | 4.909 | 1 | 1 | 40 |
GO:0070301 | cellular response to hydrogen peroxide | 3.36e-02 | 1.00e+00 | 4.874 | 1 | 2 | 41 |
GO:0004402 | histone acetyltransferase activity | 3.52e-02 | 1.00e+00 | 4.805 | 1 | 6 | 43 |
GO:0045727 | positive regulation of translation | 3.60e-02 | 1.00e+00 | 4.772 | 1 | 2 | 44 |
GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding | 3.60e-02 | 1.00e+00 | 4.772 | 1 | 4 | 44 |
GO:0003712 | transcription cofactor activity | 3.60e-02 | 1.00e+00 | 4.772 | 1 | 8 | 44 |
GO:0043966 | histone H3 acetylation | 3.68e-02 | 1.00e+00 | 4.739 | 1 | 5 | 45 |
GO:0001047 | core promoter binding | 3.68e-02 | 1.00e+00 | 4.739 | 1 | 5 | 45 |
GO:0048511 | rhythmic process | 3.68e-02 | 1.00e+00 | 4.739 | 1 | 4 | 45 |
GO:0043525 | positive regulation of neuron apoptotic process | 3.76e-02 | 1.00e+00 | 4.708 | 1 | 4 | 46 |
GO:0044297 | cell body | 3.76e-02 | 1.00e+00 | 4.708 | 1 | 2 | 46 |
GO:0019827 | stem cell maintenance | 3.84e-02 | 1.00e+00 | 4.677 | 1 | 7 | 47 |
GO:0035690 | cellular response to drug | 4.00e-02 | 1.00e+00 | 4.616 | 1 | 3 | 49 |
GO:0001669 | acrosomal vesicle | 4.00e-02 | 1.00e+00 | 4.616 | 1 | 2 | 49 |
GO:0000278 | mitotic cell cycle | 4.04e-02 | 1.00e+00 | 2.620 | 2 | 15 | 391 |
GO:0006521 | regulation of cellular amino acid metabolic process | 4.08e-02 | 1.00e+00 | 4.587 | 1 | 1 | 50 |
GO:0006986 | response to unfolded protein | 4.08e-02 | 1.00e+00 | 4.587 | 1 | 4 | 50 |
GO:0034976 | response to endoplasmic reticulum stress | 4.16e-02 | 1.00e+00 | 4.559 | 1 | 2 | 51 |
GO:0045454 | cell redox homeostasis | 4.16e-02 | 1.00e+00 | 4.559 | 1 | 1 | 51 |
GO:0005829 | cytosol | 4.20e-02 | 1.00e+00 | 1.268 | 5 | 86 | 2496 |
GO:0009611 | response to wounding | 4.24e-02 | 1.00e+00 | 4.531 | 1 | 5 | 52 |
GO:0007623 | circadian rhythm | 4.32e-02 | 1.00e+00 | 4.503 | 1 | 1 | 53 |
GO:0071300 | cellular response to retinoic acid | 4.48e-02 | 1.00e+00 | 4.450 | 1 | 1 | 55 |
GO:0051592 | response to calcium ion | 4.48e-02 | 1.00e+00 | 4.450 | 1 | 1 | 55 |
GO:0000724 | double-strand break repair via homologous recombination | 4.48e-02 | 1.00e+00 | 4.450 | 1 | 2 | 55 |
GO:0002039 | p53 binding | 4.48e-02 | 1.00e+00 | 4.450 | 1 | 4 | 55 |
GO:0043627 | response to estrogen | 4.56e-02 | 1.00e+00 | 4.424 | 1 | 5 | 56 |
GO:0000502 | proteasome complex | 4.72e-02 | 1.00e+00 | 4.373 | 1 | 3 | 58 |
GO:0006396 | RNA processing | 4.80e-02 | 1.00e+00 | 4.348 | 1 | 5 | 59 |
GO:0000786 | nucleosome | 4.80e-02 | 1.00e+00 | 4.348 | 1 | 2 | 59 |
GO:0001078 | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription | 4.80e-02 | 1.00e+00 | 4.348 | 1 | 5 | 59 |
GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity | 4.80e-02 | 1.00e+00 | 4.348 | 1 | 6 | 59 |
GO:0008013 | beta-catenin binding | 4.88e-02 | 1.00e+00 | 4.324 | 1 | 9 | 60 |
GO:0032481 | positive regulation of type I interferon production | 4.96e-02 | 1.00e+00 | 4.300 | 1 | 6 | 61 |
GO:0006987 | activation of signaling protein activity involved in unfolded protein response | 4.96e-02 | 1.00e+00 | 4.300 | 1 | 2 | 61 |
GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | 5.12e-02 | 1.00e+00 | 4.254 | 1 | 4 | 63 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 5.20e-02 | 1.00e+00 | 4.231 | 1 | 1 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 5.28e-02 | 1.00e+00 | 4.209 | 1 | 2 | 65 |
GO:0010468 | regulation of gene expression | 5.52e-02 | 1.00e+00 | 4.144 | 1 | 2 | 68 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 5.67e-02 | 1.00e+00 | 4.102 | 1 | 2 | 70 |
GO:0044267 | cellular protein metabolic process | 5.72e-02 | 1.00e+00 | 2.342 | 2 | 20 | 474 |
GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | 5.75e-02 | 1.00e+00 | 4.081 | 1 | 4 | 71 |
GO:0006334 | nucleosome assembly | 5.83e-02 | 1.00e+00 | 4.061 | 1 | 3 | 72 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 5.83e-02 | 1.00e+00 | 4.061 | 1 | 1 | 72 |
GO:0030324 | lung development | 5.83e-02 | 1.00e+00 | 4.061 | 1 | 1 | 72 |
GO:0000785 | chromatin | 5.91e-02 | 1.00e+00 | 4.041 | 1 | 6 | 73 |
GO:0000981 | sequence-specific DNA binding RNA polymerase II transcription factor activity | 5.99e-02 | 1.00e+00 | 4.022 | 1 | 4 | 74 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 5.99e-02 | 1.00e+00 | 4.022 | 1 | 2 | 74 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 6.07e-02 | 1.00e+00 | 4.002 | 1 | 1 | 75 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 6.07e-02 | 1.00e+00 | 4.002 | 1 | 1 | 75 |
GO:0071013 | catalytic step 2 spliceosome | 6.30e-02 | 1.00e+00 | 3.946 | 1 | 7 | 78 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 6.38e-02 | 1.00e+00 | 3.927 | 1 | 2 | 79 |
GO:0030968 | endoplasmic reticulum unfolded protein response | 6.38e-02 | 1.00e+00 | 3.927 | 1 | 2 | 79 |
GO:0009653 | anatomical structure morphogenesis | 6.69e-02 | 1.00e+00 | 3.856 | 1 | 2 | 83 |
GO:0009952 | anterior/posterior pattern specification | 6.69e-02 | 1.00e+00 | 3.856 | 1 | 4 | 83 |
GO:0009887 | organ morphogenesis | 6.93e-02 | 1.00e+00 | 3.805 | 1 | 5 | 86 |
GO:0090090 | negative regulation of canonical Wnt signaling pathway | 6.93e-02 | 1.00e+00 | 3.805 | 1 | 8 | 86 |
GO:0045471 | response to ethanol | 6.93e-02 | 1.00e+00 | 3.805 | 1 | 3 | 86 |
GO:0016032 | viral process | 7.07e-02 | 1.00e+00 | 2.170 | 2 | 26 | 534 |
GO:0016363 | nuclear matrix | 7.32e-02 | 1.00e+00 | 3.723 | 1 | 6 | 91 |
GO:0001649 | osteoblast differentiation | 7.39e-02 | 1.00e+00 | 3.708 | 1 | 5 | 92 |
GO:0071456 | cellular response to hypoxia | 7.39e-02 | 1.00e+00 | 3.708 | 1 | 3 | 92 |
GO:0051091 | positive regulation of sequence-specific DNA binding transcription factor activity | 7.39e-02 | 1.00e+00 | 3.708 | 1 | 7 | 92 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 7.39e-02 | 1.00e+00 | 3.708 | 1 | 1 | 92 |
GO:0005770 | late endosome | 7.47e-02 | 1.00e+00 | 3.692 | 1 | 2 | 93 |
GO:0051082 | unfolded protein binding | 7.47e-02 | 1.00e+00 | 3.692 | 1 | 7 | 93 |
GO:0006915 | apoptotic process | 7.56e-02 | 1.00e+00 | 2.115 | 2 | 12 | 555 |
GO:0051726 | regulation of cell cycle | 7.78e-02 | 1.00e+00 | 3.631 | 1 | 5 | 97 |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 7.92e-02 | 1.00e+00 | 2.076 | 2 | 37 | 570 |
GO:0005938 | cell cortex | 8.32e-02 | 1.00e+00 | 3.531 | 1 | 5 | 104 |
GO:0001934 | positive regulation of protein phosphorylation | 8.32e-02 | 1.00e+00 | 3.531 | 1 | 5 | 104 |
GO:0030529 | ribonucleoprotein complex | 8.93e-02 | 1.00e+00 | 3.424 | 1 | 5 | 112 |
GO:0000209 | protein polyubiquitination | 9.24e-02 | 1.00e+00 | 3.373 | 1 | 3 | 116 |
GO:0046983 | protein dimerization activity | 9.39e-02 | 1.00e+00 | 3.348 | 1 | 5 | 118 |
GO:0006325 | chromatin organization | 9.39e-02 | 1.00e+00 | 3.348 | 1 | 12 | 118 |
GO:0007219 | Notch signaling pathway | 9.54e-02 | 1.00e+00 | 3.324 | 1 | 5 | 120 |
GO:0007050 | cell cycle arrest | 9.85e-02 | 1.00e+00 | 3.277 | 1 | 5 | 124 |
GO:0000086 | G2/M transition of mitotic cell cycle | 1.08e-01 | 1.00e+00 | 3.144 | 1 | 4 | 136 |
GO:0016055 | Wnt signaling pathway | 1.09e-01 | 1.00e+00 | 3.123 | 1 | 4 | 138 |
GO:0007507 | heart development | 1.10e-01 | 1.00e+00 | 3.112 | 1 | 7 | 139 |
GO:0006457 | protein folding | 1.13e-01 | 1.00e+00 | 3.071 | 1 | 7 | 143 |
GO:0001077 | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription | 1.16e-01 | 1.00e+00 | 3.031 | 1 | 6 | 147 |
GO:0001666 | response to hypoxia | 1.17e-01 | 1.00e+00 | 3.012 | 1 | 7 | 149 |
GO:0000082 | G1/S transition of mitotic cell cycle | 1.17e-01 | 1.00e+00 | 3.012 | 1 | 3 | 149 |
GO:0042981 | regulation of apoptotic process | 1.18e-01 | 1.00e+00 | 3.002 | 1 | 4 | 150 |
GO:0000398 | mRNA splicing, via spliceosome | 1.28e-01 | 1.00e+00 | 2.874 | 1 | 15 | 164 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.29e-01 | 1.00e+00 | 2.865 | 1 | 12 | 165 |
GO:0034641 | cellular nitrogen compound metabolic process | 1.33e-01 | 1.00e+00 | 2.813 | 1 | 2 | 171 |
GO:0031625 | ubiquitin protein ligase binding | 1.38e-01 | 1.00e+00 | 2.755 | 1 | 5 | 178 |
GO:0032403 | protein complex binding | 1.42e-01 | 1.00e+00 | 2.715 | 1 | 6 | 183 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 1.43e-01 | 1.00e+00 | 2.708 | 1 | 22 | 184 |
GO:0016071 | mRNA metabolic process | 1.71e-01 | 1.00e+00 | 2.430 | 1 | 8 | 223 |
GO:0008380 | RNA splicing | 1.74e-01 | 1.00e+00 | 2.398 | 1 | 22 | 228 |
GO:0016070 | RNA metabolic process | 1.87e-01 | 1.00e+00 | 2.283 | 1 | 8 | 247 |
GO:0005874 | microtubule | 1.89e-01 | 1.00e+00 | 2.271 | 1 | 7 | 249 |
GO:0007283 | spermatogenesis | 1.98e-01 | 1.00e+00 | 2.198 | 1 | 3 | 262 |
GO:0008270 | zinc ion binding | 1.99e-01 | 1.00e+00 | 1.270 | 2 | 27 | 997 |
GO:0007275 | multicellular organismal development | 2.34e-01 | 1.00e+00 | 1.927 | 1 | 7 | 316 |
GO:0005813 | centrosome | 2.40e-01 | 1.00e+00 | 1.882 | 1 | 7 | 326 |
GO:0003682 | chromatin binding | 2.41e-01 | 1.00e+00 | 1.878 | 1 | 19 | 327 |
GO:0008283 | cell proliferation | 2.41e-01 | 1.00e+00 | 1.874 | 1 | 14 | 328 |
GO:0046982 | protein heterodimerization activity | 2.74e-01 | 1.00e+00 | 1.661 | 1 | 8 | 380 |
GO:0009986 | cell surface | 2.88e-01 | 1.00e+00 | 1.580 | 1 | 9 | 402 |
GO:0045892 | negative regulation of transcription, DNA-templated | 2.94e-01 | 1.00e+00 | 1.541 | 1 | 24 | 413 |
GO:0005524 | ATP binding | 2.95e-01 | 1.00e+00 | 0.889 | 2 | 31 | 1298 |
GO:0006366 | transcription from RNA polymerase II promoter | 2.98e-01 | 1.00e+00 | 1.520 | 1 | 30 | 419 |
GO:0043066 | negative regulation of apoptotic process | 3.01e-01 | 1.00e+00 | 1.503 | 1 | 16 | 424 |
GO:0045893 | positive regulation of transcription, DNA-templated | 3.33e-01 | 1.00e+00 | 1.330 | 1 | 24 | 478 |
GO:0005783 | endoplasmic reticulum | 3.76e-01 | 1.00e+00 | 1.112 | 1 | 13 | 556 |
GO:0045087 | innate immune response | 3.97e-01 | 1.00e+00 | 1.012 | 1 | 15 | 596 |
GO:0005730 | nucleolus | 4.04e-01 | 1.00e+00 | 0.551 | 2 | 66 | 1641 |
GO:0005794 | Golgi apparatus | 4.05e-01 | 1.00e+00 | 0.978 | 1 | 9 | 610 |
GO:0016020 | membrane | 4.16e-01 | 1.00e+00 | 0.516 | 2 | 46 | 1681 |
GO:0070062 | extracellular vesicular exosome | 6.18e-01 | 1.00e+00 | 0.002 | 2 | 57 | 2400 |
GO:0005737 | cytoplasm | 6.43e-01 | 1.00e+00 | -0.063 | 3 | 124 | 3767 |
GO:0044281 | small molecule metabolic process | 6.51e-01 | 1.00e+00 | -0.011 | 1 | 20 | 1211 |