Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
chia-screen-data-Fav | 2.838 | 1.56e-15 | 4.69e-04 | 3.32e-03 |
Gene Symbol | Entrez Gene ID | Frequency | chia-screen-data-Fav gene score | Best subnetwork score | Degree | Chia-Hits Primary | Chia-Hits Secondary |
---|---|---|---|---|---|---|---|
EP300 | 2033 | 22 | -2.274 | 3.120 | 415 | Yes | Yes |
ACTR6 | 64431 | 1 | -2.161 | 2.838 | 34 | Yes | - |
NCBP1 | 4686 | 6 | -2.510 | 3.149 | 40 | Yes | Yes |
YAP1 | 10413 | 94 | -4.256 | 3.538 | 53 | Yes | - |
NXF1 | 10482 | 10 | -2.426 | 3.538 | 65 | Yes | Yes |
HES6 | 55502 | 8 | -2.557 | 3.120 | 11 | Yes | Yes |
TCL1A | 8115 | 8 | -2.457 | 3.120 | 11 | Yes | Yes |
SRSF3 | 6428 | 73 | -2.992 | 3.538 | 54 | Yes | - |
YY1 | 7528 | 24 | -2.572 | 3.120 | 114 | Yes | Yes |
HNRNPU | 3192 | 76 | -2.869 | 3.538 | 139 | Yes | - |
POU5F1 | 5460 | 133 | -5.148 | 3.538 | 179 | Yes | Yes |
[ STRAP ] | 11171 | 1 | -1.840 | 2.838 | 57 | - | - |
DDIT3 | 1649 | 60 | -2.825 | 3.504 | 343 | Yes | Yes |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
SRSF3 | 6428 | NXF1 | 10482 | pp | -- | int.I2D: MINT, HPRD; int.Mint: MI:0407(direct interaction), MI:0915(physical association) |
EP300 | 2033 | YY1 | 7528 | pp | -- | int.I2D: BioGrid, BCI, HPRD; int.Transfac: -; int.Ravasi: -; int.HPRD: in vivo; int.DIP: MI:0218(physical interaction) |
HNRNPU | 3192 | NXF1 | 10482 | pp | -- | int.Intact: MI:0914(association) |
EP300 | 2033 | STRAP | 11171 | pp | -- | int.I2D: MINT; int.Mint: MI:0915(physical association) |
HNRNPU | 3192 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
EP300 | 2033 | HES6 | 55502 | pp | -- | int.I2D: IntAct |
DDIT3 | 1649 | EP300 | 2033 | pp | -- | int.Intact: MI:0915(physical association) |
EP300 | 2033 | TCL1A | 8115 | pp | -- | int.I2D: INNATEDB |
EP300 | 2033 | YAP1 | 10413 | pp | -- | int.I2D: BioGrid |
STRAP | 11171 | ACTR6 | 64431 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
NCBP1 | 4686 | NXF1 | 10482 | pp | -- | int.Mint: MI:0914(association) |
DDIT3 | 1649 | HNRNPU | 3192 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
POU5F1 | 5460 | SRSF3 | 6428 | pp | -- | int.I2D: BioGrid |
EP300 | 2033 | HNRNPU | 3192 | pp | -- | int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vitro, in vivo |
HNRNPU | 3192 | YAP1 | 10413 | pp | -- | int.I2D: HPRD; int.HPRD: in vitro, in vivo |
NXF1 | 10482 | STRAP | 11171 | pp | -- | int.I2D: HPRD; int.HPRD: yeast 2-hybrid |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0005654 | nucleoplasm | 8.95e-07 | 1.29e-02 | 3.036 | 8 | 64 | 1082 |
GO:0044212 | transcription regulatory region DNA binding | 1.17e-05 | 1.69e-01 | 4.723 | 4 | 17 | 168 |
GO:0005667 | transcription factor complex | 1.37e-05 | 1.98e-01 | 4.664 | 4 | 17 | 175 |
GO:0006406 | mRNA export from nucleus | 2.00e-05 | 2.88e-01 | 5.770 | 3 | 4 | 61 |
GO:0008134 | transcription factor binding | 4.91e-05 | 7.08e-01 | 4.197 | 4 | 18 | 242 |
GO:0042789 | mRNA transcription from RNA polymerase II promoter | 5.82e-05 | 8.39e-01 | 7.415 | 2 | 2 | 13 |
GO:0044822 | poly(A) RNA binding | 1.66e-04 | 1.00e+00 | 2.656 | 6 | 50 | 1056 |
GO:0003723 | RNA binding | 1.87e-04 | 1.00e+00 | 3.698 | 4 | 18 | 342 |
GO:0010467 | gene expression | 1.99e-04 | 1.00e+00 | 3.052 | 5 | 45 | 669 |
GO:0005515 | protein binding | 2.24e-04 | 1.00e+00 | 1.144 | 12 | 198 | 6024 |
GO:0003700 | sequence-specific DNA binding transcription factor activity | 2.45e-04 | 1.00e+00 | 2.988 | 5 | 39 | 699 |
GO:0000387 | spliceosomal snRNP assembly | 2.60e-04 | 1.00e+00 | 6.361 | 2 | 2 | 27 |
GO:0006974 | cellular response to DNA damage stimulus | 2.98e-04 | 1.00e+00 | 4.462 | 3 | 7 | 151 |
GO:0003677 | DNA binding | 3.66e-04 | 1.00e+00 | 2.450 | 6 | 49 | 1218 |
GO:0000398 | mRNA splicing, via spliceosome | 3.80e-04 | 1.00e+00 | 4.343 | 3 | 15 | 164 |
GO:0003714 | transcription corepressor activity | 4.83e-04 | 1.00e+00 | 4.225 | 3 | 11 | 178 |
GO:0031124 | mRNA 3'-end processing | 6.33e-04 | 1.00e+00 | 5.723 | 2 | 2 | 42 |
GO:0006369 | termination of RNA polymerase II transcription | 7.26e-04 | 1.00e+00 | 5.624 | 2 | 2 | 45 |
GO:0060795 | cell fate commitment involved in formation of primary germ layer | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:0060177 | regulation of angiotensin metabolic process | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:2000016 | negative regulation of determination of dorsal identity | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:1901985 | positive regulation of protein acetylation | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:0043969 | histone H2B acetylation | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:2000629 | negative regulation of miRNA metabolic process | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:0090308 | regulation of methylation-dependent chromatin silencing | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:0090081 | regulation of heart induction by regulation of canonical Wnt signaling pathway | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:0060965 | negative regulation of gene silencing by miRNA | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:0008380 | RNA splicing | 9.92e-04 | 1.00e+00 | 3.868 | 3 | 22 | 228 |
GO:0005634 | nucleus | 1.03e-03 | 1.00e+00 | 1.283 | 10 | 159 | 4559 |
GO:0003713 | transcription coactivator activity | 1.11e-03 | 1.00e+00 | 3.812 | 3 | 24 | 237 |
GO:0006355 | regulation of transcription, DNA-templated | 1.26e-03 | 1.00e+00 | 2.476 | 5 | 43 | 997 |
GO:0034696 | response to prostaglandin F | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0060242 | contact inhibition | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0014737 | positive regulation of muscle atrophy | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0006403 | RNA localization | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0005846 | nuclear cap binding complex | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0009786 | regulation of asymmetric cell division | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0090043 | regulation of tubulin deacetylation | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 2 | 2 |
GO:0035984 | cellular response to trichostatin A | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0071389 | cellular response to mineralocorticoid stimulus | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0044324 | regulation of transcription involved in anterior/posterior axis specification | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0018076 | N-terminal peptidyl-lysine acetylation | 2.70e-03 | 1.00e+00 | 8.531 | 1 | 1 | 3 |
GO:0060913 | cardiac cell fate determination | 2.70e-03 | 1.00e+00 | 8.531 | 1 | 1 | 3 |
GO:0003130 | BMP signaling pathway involved in heart induction | 2.70e-03 | 1.00e+00 | 8.531 | 1 | 1 | 3 |
GO:0010560 | positive regulation of glycoprotein biosynthetic process | 2.70e-03 | 1.00e+00 | 8.531 | 1 | 1 | 3 |
GO:0097157 | pre-mRNA intronic binding | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 1 | 4 |
GO:0018393 | internal peptidyl-lysine acetylation | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 1 | 4 |
GO:0030529 | ribonucleoprotein complex | 4.41e-03 | 1.00e+00 | 4.308 | 2 | 5 | 112 |
GO:0001714 | endodermal cell fate specification | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 |
GO:0065004 | protein-DNA complex assembly | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 |
GO:0045292 | mRNA cis splicing, via spliceosome | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 |
GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 |
GO:0043620 | regulation of DNA-templated transcription in response to stress | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 |
GO:0070934 | CRD-mediated mRNA stabilization | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 2 | 5 |
GO:0031442 | positive regulation of mRNA 3'-end processing | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 |
GO:0060298 | positive regulation of sarcomere organization | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 |
GO:0032025 | response to cobalt ion | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 |
GO:0070937 | CRD-mediated mRNA stability complex | 5.40e-03 | 1.00e+00 | 7.531 | 1 | 3 | 6 |
GO:0006366 | transcription from RNA polymerase II promoter | 5.60e-03 | 1.00e+00 | 2.990 | 3 | 30 | 419 |
GO:0006475 | internal protein amino acid acetylation | 6.29e-03 | 1.00e+00 | 7.308 | 1 | 1 | 7 |
GO:0016973 | poly(A)+ mRNA export from nucleus | 7.19e-03 | 1.00e+00 | 7.116 | 1 | 1 | 8 |
GO:0001955 | blood vessel maturation | 7.19e-03 | 1.00e+00 | 7.116 | 1 | 1 | 8 |
GO:0000339 | RNA cap binding | 7.19e-03 | 1.00e+00 | 7.116 | 1 | 1 | 8 |
GO:0042405 | nuclear inclusion body | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 2 | 9 |
GO:0060765 | regulation of androgen receptor signaling pathway | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 1 | 9 |
GO:0010225 | response to UV-C | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 2 | 9 |
GO:0006379 | mRNA cleavage | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 1 | 9 |
GO:0060394 | negative regulation of pathway-restricted SMAD protein phosphorylation | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 1 | 9 |
GO:0006983 | ER overload response | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 1 | 9 |
GO:0035259 | glucocorticoid receptor binding | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 1 | 9 |
GO:0045793 | positive regulation of cell size | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 2 | 9 |
GO:0000400 | four-way junction DNA binding | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 1 | 9 |
GO:0035413 | positive regulation of catenin import into nucleus | 8.98e-03 | 1.00e+00 | 6.794 | 1 | 2 | 10 |
GO:0016407 | acetyltransferase activity | 8.98e-03 | 1.00e+00 | 6.794 | 1 | 2 | 10 |
GO:0043923 | positive regulation by host of viral transcription | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 1 | 11 |
GO:0005845 | mRNA cap binding complex | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 1 | 11 |
GO:0032797 | SMN complex | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 1 | 11 |
GO:0033160 | positive regulation of protein import into nucleus, translocation | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 3 | 11 |
GO:0030277 | maintenance of gastrointestinal epithelium | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 2 | 11 |
GO:0045662 | negative regulation of myoblast differentiation | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 3 | 11 |
GO:0042975 | peroxisome proliferator activated receptor binding | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 1 | 11 |
GO:0045120 | pronucleus | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 2 | 11 |
GO:0060391 | positive regulation of SMAD protein import into nucleus | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 4 | 11 |
GO:0016607 | nuclear speck | 1.01e-02 | 1.00e+00 | 3.689 | 2 | 12 | 172 |
GO:0010633 | negative regulation of epithelial cell migration | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 1 | 12 |
GO:0008334 | histone mRNA metabolic process | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 1 | 12 |
GO:0035198 | miRNA binding | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 1 | 12 |
GO:0016032 | viral process | 1.09e-02 | 1.00e+00 | 2.640 | 3 | 26 | 534 |
GO:0071480 | cellular response to gamma radiation | 1.17e-02 | 1.00e+00 | 6.415 | 1 | 1 | 13 |
GO:0051019 | mitogen-activated protein kinase binding | 1.17e-02 | 1.00e+00 | 6.415 | 1 | 2 | 13 |
GO:0016746 | transferase activity, transferring acyl groups | 1.17e-02 | 1.00e+00 | 6.415 | 1 | 1 | 13 |
GO:0000346 | transcription export complex | 1.17e-02 | 1.00e+00 | 6.415 | 1 | 1 | 13 |
GO:0070542 | response to fatty acid | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 1 | 14 |
GO:0031011 | Ino80 complex | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 6 | 14 |
GO:0032993 | protein-DNA complex | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 2 | 14 |
GO:0005487 | nucleocytoplasmic transporter activity | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 3 | 14 |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 1.31e-02 | 1.00e+00 | 2.546 | 3 | 37 | 570 |
GO:0001824 | blastocyst development | 1.34e-02 | 1.00e+00 | 6.209 | 1 | 2 | 15 |
GO:1990090 | cellular response to nerve growth factor stimulus | 1.34e-02 | 1.00e+00 | 6.209 | 1 | 1 | 15 |
GO:0043274 | phospholipase binding | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 1 | 16 |
GO:0051276 | chromosome organization | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 2 | 16 |
GO:0034719 | SMN-Sm protein complex | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 1 | 16 |
GO:0048593 | camera-type eye morphogenesis | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 1 | 16 |
GO:0005829 | cytosol | 1.51e-02 | 1.00e+00 | 1.415 | 6 | 86 | 2496 |
GO:0045773 | positive regulation of axon extension | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 1 | 18 |
GO:0033613 | activating transcription factor binding | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 3 | 18 |
GO:0010719 | negative regulation of epithelial to mesenchymal transition | 1.70e-02 | 1.00e+00 | 5.868 | 1 | 1 | 19 |
GO:0035257 | nuclear hormone receptor binding | 1.70e-02 | 1.00e+00 | 5.868 | 1 | 1 | 19 |
GO:0007399 | nervous system development | 1.77e-02 | 1.00e+00 | 3.264 | 2 | 6 | 231 |
GO:0071549 | cellular response to dexamethasone stimulus | 1.79e-02 | 1.00e+00 | 5.794 | 1 | 3 | 20 |
GO:0010942 | positive regulation of cell death | 1.79e-02 | 1.00e+00 | 5.794 | 1 | 1 | 20 |
GO:0032757 | positive regulation of interleukin-8 production | 1.79e-02 | 1.00e+00 | 5.794 | 1 | 1 | 20 |
GO:0000123 | histone acetyltransferase complex | 1.88e-02 | 1.00e+00 | 5.723 | 1 | 6 | 21 |
GO:0032967 | positive regulation of collagen biosynthetic process | 1.88e-02 | 1.00e+00 | 5.723 | 1 | 3 | 21 |
GO:0045862 | positive regulation of proteolysis | 1.88e-02 | 1.00e+00 | 5.723 | 1 | 2 | 21 |
GO:0003823 | antigen binding | 1.97e-02 | 1.00e+00 | 5.656 | 1 | 2 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 1.97e-02 | 1.00e+00 | 5.656 | 1 | 2 | 22 |
GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | 2.05e-02 | 1.00e+00 | 5.592 | 1 | 1 | 23 |
GO:0034660 | ncRNA metabolic process | 2.05e-02 | 1.00e+00 | 5.592 | 1 | 1 | 23 |
GO:0043388 | positive regulation of DNA binding | 2.14e-02 | 1.00e+00 | 5.531 | 1 | 2 | 24 |
GO:0043425 | bHLH transcription factor binding | 2.14e-02 | 1.00e+00 | 5.531 | 1 | 1 | 24 |
GO:0000166 | nucleotide binding | 2.20e-02 | 1.00e+00 | 3.099 | 2 | 13 | 259 |
GO:0031047 | gene silencing by RNA | 2.23e-02 | 1.00e+00 | 5.472 | 1 | 2 | 25 |
GO:0051059 | NF-kappaB binding | 2.23e-02 | 1.00e+00 | 5.472 | 1 | 3 | 25 |
GO:0031519 | PcG protein complex | 2.23e-02 | 1.00e+00 | 5.472 | 1 | 1 | 25 |
GO:0006357 | regulation of transcription from RNA polymerase II promoter | 2.28e-02 | 1.00e+00 | 3.071 | 2 | 23 | 264 |
GO:0035329 | hippo signaling | 2.32e-02 | 1.00e+00 | 5.415 | 1 | 5 | 26 |
GO:0051209 | release of sequestered calcium ion into cytosol | 2.32e-02 | 1.00e+00 | 5.415 | 1 | 1 | 26 |
GO:0048565 | digestive tract development | 2.32e-02 | 1.00e+00 | 5.415 | 1 | 2 | 26 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 2.32e-02 | 1.00e+00 | 5.415 | 1 | 1 | 26 |
GO:0034612 | response to tumor necrosis factor | 2.41e-02 | 1.00e+00 | 5.361 | 1 | 2 | 27 |
GO:0043967 | histone H4 acetylation | 2.41e-02 | 1.00e+00 | 5.361 | 1 | 1 | 27 |
GO:0050714 | positive regulation of protein secretion | 2.50e-02 | 1.00e+00 | 5.308 | 1 | 3 | 28 |
GO:0034644 | cellular response to UV | 2.67e-02 | 1.00e+00 | 5.209 | 1 | 1 | 30 |
GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | 2.67e-02 | 1.00e+00 | 5.209 | 1 | 1 | 30 |
GO:0006370 | 7-methylguanosine mRNA capping | 2.67e-02 | 1.00e+00 | 5.209 | 1 | 5 | 30 |
GO:0042594 | response to starvation | 2.76e-02 | 1.00e+00 | 5.161 | 1 | 4 | 31 |
GO:0043491 | protein kinase B signaling | 2.85e-02 | 1.00e+00 | 5.116 | 1 | 2 | 32 |
GO:1903507 | negative regulation of nucleic acid-templated transcription | 2.85e-02 | 1.00e+00 | 5.116 | 1 | 2 | 32 |
GO:0030154 | cell differentiation | 2.91e-02 | 1.00e+00 | 2.882 | 2 | 5 | 301 |
GO:0071333 | cellular response to glucose stimulus | 2.94e-02 | 1.00e+00 | 5.071 | 1 | 1 | 33 |
GO:0001756 | somitogenesis | 2.94e-02 | 1.00e+00 | 5.071 | 1 | 1 | 33 |
GO:0005737 | cytoplasm | 3.06e-02 | 1.00e+00 | 1.044 | 7 | 124 | 3767 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 3.09e-02 | 1.00e+00 | 2.077 | 3 | 41 | 789 |
GO:0001102 | RNA polymerase II activating transcription factor binding | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 1 | 36 |
GO:0006446 | regulation of translational initiation | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 4 | 36 |
GO:0032092 | positive regulation of protein binding | 3.37e-02 | 1.00e+00 | 4.868 | 1 | 2 | 38 |
GO:0031490 | chromatin DNA binding | 3.37e-02 | 1.00e+00 | 4.868 | 1 | 2 | 38 |
GO:0050681 | androgen receptor binding | 3.37e-02 | 1.00e+00 | 4.868 | 1 | 1 | 38 |
GO:0035019 | somatic stem cell maintenance | 3.55e-02 | 1.00e+00 | 4.794 | 1 | 6 | 40 |
GO:0007519 | skeletal muscle tissue development | 3.55e-02 | 1.00e+00 | 4.794 | 1 | 2 | 40 |
GO:0046332 | SMAD binding | 3.55e-02 | 1.00e+00 | 4.794 | 1 | 2 | 40 |
GO:0071320 | cellular response to cAMP | 3.55e-02 | 1.00e+00 | 4.794 | 1 | 1 | 40 |
GO:0070301 | cellular response to hydrogen peroxide | 3.63e-02 | 1.00e+00 | 4.758 | 1 | 2 | 41 |
GO:0043565 | sequence-specific DNA binding | 3.76e-02 | 1.00e+00 | 2.681 | 2 | 11 | 346 |
GO:0004402 | histone acetyltransferase activity | 3.81e-02 | 1.00e+00 | 4.689 | 1 | 6 | 43 |
GO:0050434 | positive regulation of viral transcription | 3.90e-02 | 1.00e+00 | 4.656 | 1 | 5 | 44 |
GO:0045727 | positive regulation of translation | 3.90e-02 | 1.00e+00 | 4.656 | 1 | 2 | 44 |
GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding | 3.90e-02 | 1.00e+00 | 4.656 | 1 | 4 | 44 |
GO:0003712 | transcription cofactor activity | 3.90e-02 | 1.00e+00 | 4.656 | 1 | 8 | 44 |
GO:0043966 | histone H3 acetylation | 3.98e-02 | 1.00e+00 | 4.624 | 1 | 5 | 45 |
GO:0001047 | core promoter binding | 3.98e-02 | 1.00e+00 | 4.624 | 1 | 5 | 45 |
GO:0043525 | positive regulation of neuron apoptotic process | 4.07e-02 | 1.00e+00 | 4.592 | 1 | 4 | 46 |
GO:0019827 | stem cell maintenance | 4.16e-02 | 1.00e+00 | 4.561 | 1 | 7 | 47 |
GO:0035690 | cellular response to drug | 4.33e-02 | 1.00e+00 | 4.501 | 1 | 3 | 49 |
GO:0006986 | response to unfolded protein | 4.42e-02 | 1.00e+00 | 4.472 | 1 | 4 | 50 |
GO:0034976 | response to endoplasmic reticulum stress | 4.50e-02 | 1.00e+00 | 4.443 | 1 | 2 | 51 |
GO:0045454 | cell redox homeostasis | 4.50e-02 | 1.00e+00 | 4.443 | 1 | 1 | 51 |
GO:0050680 | negative regulation of epithelial cell proliferation | 4.50e-02 | 1.00e+00 | 4.443 | 1 | 2 | 51 |
GO:0009611 | response to wounding | 4.59e-02 | 1.00e+00 | 4.415 | 1 | 5 | 52 |
GO:0007623 | circadian rhythm | 4.68e-02 | 1.00e+00 | 4.388 | 1 | 1 | 53 |
GO:0071300 | cellular response to retinoic acid | 4.85e-02 | 1.00e+00 | 4.334 | 1 | 1 | 55 |
GO:0051592 | response to calcium ion | 4.85e-02 | 1.00e+00 | 4.334 | 1 | 1 | 55 |
GO:0000724 | double-strand break repair via homologous recombination | 4.85e-02 | 1.00e+00 | 4.334 | 1 | 2 | 55 |
GO:0002039 | p53 binding | 4.85e-02 | 1.00e+00 | 4.334 | 1 | 4 | 55 |
GO:0043627 | response to estrogen | 4.93e-02 | 1.00e+00 | 4.308 | 1 | 5 | 56 |
GO:0005643 | nuclear pore | 5.02e-02 | 1.00e+00 | 4.283 | 1 | 11 | 57 |
GO:0006396 | RNA processing | 5.19e-02 | 1.00e+00 | 4.233 | 1 | 5 | 59 |
GO:0001078 | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription | 5.19e-02 | 1.00e+00 | 4.233 | 1 | 5 | 59 |
GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity | 5.19e-02 | 1.00e+00 | 4.233 | 1 | 6 | 59 |
GO:0008013 | beta-catenin binding | 5.28e-02 | 1.00e+00 | 4.209 | 1 | 9 | 60 |
GO:0032481 | positive regulation of type I interferon production | 5.36e-02 | 1.00e+00 | 4.185 | 1 | 6 | 61 |
GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway | 5.36e-02 | 1.00e+00 | 4.185 | 1 | 2 | 61 |
GO:0006987 | activation of signaling protein activity involved in unfolded protein response | 5.36e-02 | 1.00e+00 | 4.185 | 1 | 2 | 61 |
GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | 5.53e-02 | 1.00e+00 | 4.138 | 1 | 4 | 63 |
GO:0006368 | transcription elongation from RNA polymerase II promoter | 5.88e-02 | 1.00e+00 | 4.050 | 1 | 6 | 67 |
GO:0010468 | regulation of gene expression | 5.96e-02 | 1.00e+00 | 4.028 | 1 | 2 | 68 |
GO:0003729 | mRNA binding | 6.30e-02 | 1.00e+00 | 3.946 | 1 | 4 | 72 |
GO:0030324 | lung development | 6.30e-02 | 1.00e+00 | 3.946 | 1 | 1 | 72 |
GO:0000785 | chromatin | 6.39e-02 | 1.00e+00 | 3.926 | 1 | 6 | 73 |
GO:0000981 | sequence-specific DNA binding RNA polymerase II transcription factor activity | 6.47e-02 | 1.00e+00 | 3.906 | 1 | 4 | 74 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 6.56e-02 | 1.00e+00 | 3.887 | 1 | 1 | 75 |
GO:0001889 | liver development | 6.72e-02 | 1.00e+00 | 3.849 | 1 | 3 | 77 |
GO:0071013 | catalytic step 2 spliceosome | 6.81e-02 | 1.00e+00 | 3.830 | 1 | 7 | 78 |
GO:0030968 | endoplasmic reticulum unfolded protein response | 6.89e-02 | 1.00e+00 | 3.812 | 1 | 2 | 79 |
GO:0009653 | anatomical structure morphogenesis | 7.23e-02 | 1.00e+00 | 3.741 | 1 | 2 | 83 |
GO:0009952 | anterior/posterior pattern specification | 7.23e-02 | 1.00e+00 | 3.741 | 1 | 4 | 83 |
GO:0009887 | organ morphogenesis | 7.48e-02 | 1.00e+00 | 3.689 | 1 | 5 | 86 |
GO:0090090 | negative regulation of canonical Wnt signaling pathway | 7.48e-02 | 1.00e+00 | 3.689 | 1 | 8 | 86 |
GO:0045471 | response to ethanol | 7.48e-02 | 1.00e+00 | 3.689 | 1 | 3 | 86 |
GO:0016363 | nuclear matrix | 7.90e-02 | 1.00e+00 | 3.608 | 1 | 6 | 91 |
GO:0001649 | osteoblast differentiation | 7.99e-02 | 1.00e+00 | 3.592 | 1 | 5 | 92 |
GO:0071456 | cellular response to hypoxia | 7.99e-02 | 1.00e+00 | 3.592 | 1 | 3 | 92 |
GO:0051091 | positive regulation of sequence-specific DNA binding transcription factor activity | 7.99e-02 | 1.00e+00 | 3.592 | 1 | 7 | 92 |
GO:0005770 | late endosome | 8.07e-02 | 1.00e+00 | 3.576 | 1 | 2 | 93 |
GO:0051726 | regulation of cell cycle | 8.40e-02 | 1.00e+00 | 3.516 | 1 | 5 | 97 |
GO:0005938 | cell cortex | 8.98e-02 | 1.00e+00 | 3.415 | 1 | 5 | 104 |
GO:0001934 | positive regulation of protein phosphorylation | 8.98e-02 | 1.00e+00 | 3.415 | 1 | 5 | 104 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 9.81e-02 | 1.00e+00 | 3.283 | 1 | 4 | 114 |
GO:0046983 | protein dimerization activity | 1.01e-01 | 1.00e+00 | 3.233 | 1 | 5 | 118 |
GO:0006325 | chromatin organization | 1.01e-01 | 1.00e+00 | 3.233 | 1 | 12 | 118 |
GO:0007219 | Notch signaling pathway | 1.03e-01 | 1.00e+00 | 3.209 | 1 | 5 | 120 |
GO:0007050 | cell cycle arrest | 1.06e-01 | 1.00e+00 | 3.161 | 1 | 5 | 124 |
GO:0007179 | transforming growth factor beta receptor signaling pathway | 1.09e-01 | 1.00e+00 | 3.116 | 1 | 11 | 128 |
GO:0000086 | G2/M transition of mitotic cell cycle | 1.16e-01 | 1.00e+00 | 3.028 | 1 | 4 | 136 |
GO:0007507 | heart development | 1.18e-01 | 1.00e+00 | 2.997 | 1 | 7 | 139 |
GO:0016055 | Wnt signaling pathway | 1.18e-01 | 1.00e+00 | 3.007 | 1 | 4 | 138 |
GO:0001666 | response to hypoxia | 1.26e-01 | 1.00e+00 | 2.896 | 1 | 7 | 149 |
GO:0006351 | transcription, DNA-templated | 1.35e-01 | 1.00e+00 | 1.203 | 3 | 57 | 1446 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.39e-01 | 1.00e+00 | 2.749 | 1 | 12 | 165 |
GO:0031625 | ubiquitin protein ligase binding | 1.49e-01 | 1.00e+00 | 2.640 | 1 | 5 | 178 |
GO:0032403 | protein complex binding | 1.53e-01 | 1.00e+00 | 2.600 | 1 | 6 | 183 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 1.54e-01 | 1.00e+00 | 2.592 | 1 | 22 | 184 |
GO:0016071 | mRNA metabolic process | 1.83e-01 | 1.00e+00 | 2.315 | 1 | 8 | 223 |
GO:0016070 | RNA metabolic process | 2.01e-01 | 1.00e+00 | 2.167 | 1 | 8 | 247 |
GO:0005102 | receptor binding | 2.11e-01 | 1.00e+00 | 2.093 | 1 | 2 | 260 |
GO:0007283 | spermatogenesis | 2.12e-01 | 1.00e+00 | 2.082 | 1 | 3 | 262 |
GO:0008270 | zinc ion binding | 2.25e-01 | 1.00e+00 | 1.154 | 2 | 27 | 997 |
GO:0005856 | cytoskeleton | 2.33e-01 | 1.00e+00 | 1.931 | 1 | 9 | 291 |
GO:0007275 | multicellular organismal development | 2.50e-01 | 1.00e+00 | 1.812 | 1 | 7 | 316 |
GO:0003682 | chromatin binding | 2.58e-01 | 1.00e+00 | 1.762 | 1 | 19 | 327 |
GO:0008283 | cell proliferation | 2.59e-01 | 1.00e+00 | 1.758 | 1 | 14 | 328 |
GO:0030054 | cell junction | 2.64e-01 | 1.00e+00 | 1.723 | 1 | 5 | 336 |
GO:0046982 | protein heterodimerization activity | 2.93e-01 | 1.00e+00 | 1.546 | 1 | 8 | 380 |
GO:0000278 | mitotic cell cycle | 3.01e-01 | 1.00e+00 | 1.505 | 1 | 15 | 391 |
GO:0009986 | cell surface | 3.08e-01 | 1.00e+00 | 1.465 | 1 | 9 | 402 |
GO:0045892 | negative regulation of transcription, DNA-templated | 3.15e-01 | 1.00e+00 | 1.426 | 1 | 24 | 413 |
GO:0044267 | cellular protein metabolic process | 3.52e-01 | 1.00e+00 | 1.227 | 1 | 20 | 474 |
GO:0045893 | positive regulation of transcription, DNA-templated | 3.55e-01 | 1.00e+00 | 1.215 | 1 | 24 | 478 |
GO:0006915 | apoptotic process | 4.00e-01 | 1.00e+00 | 0.999 | 1 | 12 | 555 |
GO:0005783 | endoplasmic reticulum | 4.00e-01 | 1.00e+00 | 0.997 | 1 | 13 | 556 |
GO:0045087 | innate immune response | 4.22e-01 | 1.00e+00 | 0.896 | 1 | 15 | 596 |
GO:0005730 | nucleolus | 4.45e-01 | 1.00e+00 | 0.435 | 2 | 66 | 1641 |
GO:0005739 | mitochondrion | 6.06e-01 | 1.00e+00 | 0.153 | 1 | 23 | 998 |
GO:0005886 | plasma membrane | 7.05e-01 | 1.00e+00 | -0.219 | 2 | 49 | 2582 |
GO:0005524 | ATP binding | 7.07e-01 | 1.00e+00 | -0.226 | 1 | 31 | 1298 |
GO:0016020 | membrane | 8.00e-01 | 1.00e+00 | -0.599 | 1 | 46 | 1681 |