meta-int-snw-8861

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-11277 wolf-screen-ratio-mammosphere-adherent 0.882 1.09e-07 9.11e-04 1.96e-03 10 9
int-snw-8861 wolf-screen-ratio-mammosphere-adherent 0.937 1.33e-15 2.35e-03 3.86e-02 13 13
reg-snw-4522 wolf-screen-ratio-mammosphere-adherent 0.815 1.50e-06 3.75e-03 6.95e-03 14 12
reg-snw-56655 wolf-screen-ratio-mammosphere-adherent 0.828 9.29e-07 2.91e-03 5.53e-03 8 7
reg-snw-317781 wolf-screen-ratio-mammosphere-adherent 0.823 1.13e-06 3.23e-03 6.07e-03 9 9
reg-snw-10213 wolf-screen-ratio-mammosphere-adherent 0.815 1.49e-06 3.74e-03 6.93e-03 7 6
reg-snw-55660 wolf-screen-ratio-mammosphere-adherent 0.830 8.54e-07 2.78e-03 5.31e-03 6 6
reg-snw-1642 wolf-screen-ratio-mammosphere-adherent 0.875 1.48e-07 1.08e-03 2.28e-03 5 4
wolf-screen-ratio-mammosphere-adherent-meta-int-snw-8861 subnetwork

Genes (38)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
PSMB1 5689 610.6880.901113Yes-
PSMA3 5684 900.5330.815238Yes-
PSMA2 5683 1121.0931.106108Yes-
POLR2F 5435 620.8910.95626Yes-
VARS 7407 860.5491.002204Yes-
DDX51 317781 530.0590.823210Yes-
CAD 790 910.8070.973400--
EIF6 3692 670.7000.876316Yes-
PSMD1 5707 860.8360.830118Yes-
EEF2 1938 640.8901.043301Yes-
EFTUD2 9343 930.8830.956108Yes-
PSMD14 10213 440.2990.81532--
TUBG1 7283 980.9740.97391Yes-
PSMD11 5717 1241.0951.106218Yes-
POLR1B 84172 120.6130.988184Yes-
RAN 5901 890.6320.899258Yes-
HSPD1 3329 700.9131.035325Yes-
PRMT3 10196 490.4310.81526--
PRPF40A 55660 250.4230.830106Yes-
MTHFD1 4522 490.1940.81526Yes-
RBX1 9978 1151.1850.934148Yes-
LDB1 8861 80.3850.93745Yes-
PSMC3 5702 510.7191.002276Yes-
HNRNPC 3183 1081.8120.973181Yes-
PSMB7 5695 1180.9820.93490Yes-
PSMA1 5682 1000.9960.878152Yes-
TREX1 11277 51-0.0510.88291Yes-
POLE4 56655 630.1770.82856--
PSMB3 5691 640.6680.90119Yes-
RPA1 6117 510.4250.86574--
PGD 5226 891.2011.106152Yes-
ACO2 50 651.0001.076191Yes-
RUVBL1 8607 950.7200.973469Yes-
PSMD3 5709 1000.9861.106201Yes-
PSMB2 5690 1160.8770.956169Yes-
ACTB 60 1341.1531.151610Yes-
RUVBL2 10856 950.6930.956532Yes-
DDB1 1642 110.5150.87569--

Interactions (201)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMA3 5684 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, Krogan_Core
HNRNPC 3183 PSMA3 5684 pp -- int.I2D: BioGrid
EEF2 1938 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
EEF2 1938 PGD 5226 pp -- int.I2D: BioGrid_Yeast
ACO2 50 RPA1 6117 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
EEF2 1938 PSMC3 5702 pp -- int.I2D: YeastLow, BioGrid_Yeast
PSMB2 5690 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMA1 5682 PSMB2 5690 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
EEF2 1938 HSPD1 3329 pp -- int.I2D: YeastLow, YeastMedium
PSMD11 5717 RUVBL1 8607 pp -- int.I2D: YeastLow
PSMA1 5682 PSMB1 5689 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, BIND_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, IntAct, IntAct_Mouse, IntAct_Yeast, Yu_GoldStd
PSMB1 5689 PSMC3 5702 pp -- int.I2D: YeastLow
EFTUD2 9343 RUVBL2 10856 pd < reg.ITFP.txt: no annot
EFTUD2 9343 RUVBL2 10856 pp -- int.I2D: BioGrid
CAD 790 RPA1 6117 pd < reg.ITFP.txt: no annot
MTHFD1 4522 PSMA3 5684 pp -- int.I2D: BioGrid
EEF2 1938 PSMB3 5691 pp -- int.I2D: IntAct_Fly, BioGrid_Fly, BIND_Fly, FlyLow, MINT_Fly
EEF2 1938 DDX51 317781 pp -- int.I2D: IntAct_Yeast
PSMB2 5690 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMC3 5702 VARS 7407 pp -- int.I2D: BioGrid_Yeast
ACO2 50 POLR1B 84172 pp -- int.I2D: YeastLow
PSMD1 5707 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, Krogan_Core
ACTB 60 RUVBL1 8607 pp -- int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast
RPA1 6117 POLR1B 84172 pp -- int.I2D: YeastLow
ACTB 60 HSPD1 3329 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastLow
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PGD 5226 RAN 5901 pp -- int.I2D: YeastLow
PSMB3 5691 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPA1 6117 RUVBL1 8607 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
RPA1 6117 VARS 7407 pp -- int.I2D: YeastLow
CAD 790 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMB1 5689 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RAN 5901 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMB1 5689 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastHigh, IntAct, Yu_GoldStd;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
PSMB2 5690 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMC3 5702 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMB3 5691 PSMD3 5709 pp -- int.I2D: YeastLow
PSMA2 5683 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
CAD 790 RUVBL1 8607 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL1 8607 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
RPA1 6117 TREX1 11277 pp -- int.I2D: BCI;
int.HPRD: in vitro
PSMA3 5684 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMD14 10213 pp -- int.I2D: BioGrid, BioGrid_Yeast
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACO2 50 HSPD1 3329 pp -- int.I2D: IntAct_Yeast
RPA1 6117 RUVBL2 10856 pp -- int.I2D: YeastLow
ACO2 50 PSMD11 5717 pp -- int.I2D: YeastLow
PSMB1 5689 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, MINT, YeastHigh, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast;
int.Mint: MI:0915(physical association)
PSMD3 5709 POLR1B 84172 pp -- int.I2D: IntAct_Yeast, YeastLow
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
TREX1 11277 DDX51 317781 pd <> reg.ITFP.txt: no annot
HSPD1 3329 RPA1 6117 pp -- int.I2D: YeastLow, IntAct_Yeast
PSMA1 5682 PSMB3 5691 pp -- int.Intact: MI:0914(association);
int.I2D: IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Yeast, YeastHigh, BioGrid_Yeast
ACO2 50 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
DDB1 1642 PSMB2 5690 pd > reg.ITFP.txt: no annot
PSMC3 5702 PSMD3 5709 pd < reg.ITFP.txt: no annot
PSMC3 5702 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, Krogan_NonCore, YeastHigh
PSMD3 5709 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
EIF6 3692 PGD 5226 pp -- int.I2D: YeastLow
PSMD1 5707 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast
DDB1 1642 HSPD1 3329 pd > reg.ITFP.txt: no annot
ACTB 60 EEF2 1938 pp -- int.I2D: YeastLow, IntAct_Yeast
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastMedium
HSPD1 3329 EIF6 3692 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 PSMA2 5683 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
TUBG1 7283 VARS 7407 pd < reg.ITFP.txt: no annot
ACTB 60 PSMA3 5684 pp -- int.I2D: BioGrid, BioGrid_Yeast
HSPD1 3329 POLR1B 84172 pp -- int.I2D: YeastLow
RUVBL1 8607 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
RUVBL1 8607 RUVBL2 10856 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid, BioGrid_Mouse, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct, IntAct_Fly, IntAct_Worm, IntAct_Yeast, INTEROLOG, MINT_Worm, MINT_Yeast, BCI, BioGrid_Fly, BIND_Fly, BIND_Worm, FlyHigh, INNATEDB, Krogan_Core, MIPS, YeastHigh, Yu_GoldStd;
int.Ravasi: -;
int.HPRD: in vitro, in vivo, yeast 2-hybrid;
int.DIP: MI:0915(physical association)
HSPD1 3329 PRPF40A 55660 pd < reg.ITFP.txt: no annot
EEF2 1938 PSMA3 5684 pp -- int.I2D: BioGrid
ACO2 50 EIF6 3692 pp -- int.I2D: YeastLow
PSMA1 5682 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, BioGrid, YeastMedium
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
MTHFD1 4522 PRMT3 10196 pd < reg.ITFP.txt: no annot
EEF2 1938 RPA1 6117 pp -- int.I2D: YeastLow, Krogan_NonCore
DDB1 1642 TUBG1 7283 pd > reg.ITFP.txt: no annot
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
EEF2 1938 PSMD3 5709 pp -- int.I2D: Krogan_NonCore
ACTB 60 CAD 790 pp -- int.I2D: IntAct_Yeast
PSMD1 5707 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMD1 5707 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast
LDB1 8861 POLR1B 84172 pp -- int.Intact: MI:0915(physical association)
PSMA1 5682 RPA1 6117 pd < reg.ITFP.txt: no annot
PSMB7 5695 RBX1 9978 pd < reg.ITFP.txt: no annot
PSMA3 5684 RUVBL2 10856 pp -- int.I2D: YeastLow
CAD 790 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PGD 5226 PSMD11 5717 pp -- int.I2D: YeastLow
PSMA2 5683 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast, YeastLow
HNRNPC 3183 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMD3 5709 RUVBL2 10856 pp -- int.I2D: YeastLow
VARS 7407 POLE4 56655 pd <> reg.ITFP.txt: no annot
PSMA2 5683 PSMB3 5691 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd
PSMD3 5709 TUBG1 7283 pd > reg.ITFP.txt: no annot
PSMD11 5717 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, IntAct, INTEROLOG
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
RUVBL2 10856 POLR1B 84172 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
CAD 790 DDX51 317781 pp -- int.I2D: IntAct_Yeast
HSPD1 3329 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
CAD 790 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast
VARS 7407 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
HNRNPC 3183 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMA2 5683 POLE4 56655 pd < reg.ITFP.txt: no annot
PGD 5226 POLR1B 84172 pp -- int.I2D: YeastLow
PSMB1 5689 PSMB7 5695 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastLow, IntAct, Krogan_Core, MINT_Yeast, Yu_GoldStd;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
VARS 7407 RUVBL1 8607 pd <> reg.ITFP.txt: no annot
PSMA3 5684 PSMD1 5707 pp -- int.I2D: BioGrid, BioGrid_Yeast
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 EFTUD2 9343 pp -- int.I2D: BioGrid
PSMB2 5690 RUVBL2 10856 pd < reg.ITFP.txt: no annot
HSPD1 3329 PSMA3 5684 pp -- int.I2D: BioGrid
PGD 5226 PSMD3 5709 pp -- int.I2D: YeastLow
PSMB7 5695 DDX51 317781 pd < reg.ITFP.txt: no annot
RUVBL1 8607 POLR1B 84172 pp -- int.I2D: YeastLow
PSMD11 5717 POLR1B 84172 pp -- int.I2D: YeastLow
PSMB7 5695 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, MINT_Yeast, YeastLow, Krogan_Core
PRMT3 10196 POLR1B 84172 pd > reg.ITFP.txt: no annot
MTHFD1 4522 RUVBL1 8607 pd < reg.ITFP.txt: no annot
MTHFD1 4522 VARS 7407 pd < reg.ITFP.txt: no annot
MTHFD1 4522 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
CAD 790 POLR1B 84172 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMC3 5702 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh
TUBG1 7283 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 RUVBL1 8607 pp -- int.I2D: BioGrid
PSMB7 5695 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RAN 5901 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, NON_CORE
RAN 5901 VARS 7407 pd < reg.ITFP.txt: no annot
TUBG1 7283 RUVBL1 8607 pd < reg.ITFP.txt: no annot
POLR2F 5435 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 RAN 5901 pp -- int.I2D: IntAct_Yeast
PSMB3 5691 PSMB7 5695 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, YeastHigh, HPRD, Krogan_Core, MINT_Yeast, MIPS;
int.HPRD: yeast 2-hybrid
PSMB2 5690 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
MTHFD1 4522 RPA1 6117 pd < reg.ITFP.txt: no annot
VARS 7407 DDX51 317781 pd <> reg.ITFP.txt: no annot
ACTB 60 POLR1B 84172 pp -- int.I2D: BIND, BIND_Mouse
RUVBL1 8607 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMD3 5709 VARS 7407 pd <> reg.ITFP.txt: no annot
PSMB7 5695 PSMD1 5707 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct
PSMA1 5682 PSMA3 5684 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, CE_DATA, HPRD, IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Worm, IntAct_Yeast, MINT_Worm, BioGrid, BioGrid_Fly, BIND_Fly, BIND_Yeast, FlyHigh, Krogan_Core, MINT_Fly, MINT_Yeast, YeastHigh, Yu_GoldStd;
int.HPRD: in vitro
PSMB7 5695 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMA2 5683 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMC3 5702 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast
PSMA1 5682 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMD11 5717 TUBG1 7283 pd > reg.ITFP.txt: no annot
ACTB 60 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMC3 5702 PSMD11 5717 pd < reg.ITFP.txt: no annot
PSMC3 5702 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh
PSMA1 5682 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, INTEROLOG, MINT, Yu_GoldStd, BCI, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
PSMB1 5689 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
MTHFD1 4522 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 LDB1 8861 pp -- int.Intact: MI:0915(physical association);
int.I2D: VidalHuman_non_core
CAD 790 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 DDX51 317781 pd < reg.ITFP.txt: no annot
PSMD11 5717 EFTUD2 9343 pd > reg.ITFP.txt: no annot
PSMA3 5684 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast, BioGrid, YeastLow
PSMA1 5682 PRPF40A 55660 pd < reg.ITFP.txt: no annot
ACO2 50 PGD 5226 pp -- int.I2D: YeastLow
PSMD11 5717 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMB3 5691 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMB1 5689 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, IntAct_Yeast, YeastHigh
VARS 7407 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
EIF6 3692 POLR1B 84172 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
PSMC3 5702 POLR1B 84172 pp -- int.I2D: BioGrid_Yeast
EEF2 1938 RUVBL2 10856 pp -- int.I2D: YeastLow, BioGrid_Yeast, IntAct_Yeast
PSMB1 5689 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMD1 5707 RUVBL2 10856 pp -- int.I2D: IntAct_Yeast
ACO2 50 RUVBL1 8607 pp -- int.I2D: YeastLow
PSMA3 5684 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMB1 5689 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMA3 5684 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD11 5717 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB2 5690 VARS 7407 pd < reg.ITFP.txt: no annot
EIF6 3692 PSMB1 5689 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMA2 5683 PSMB1 5689 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, BCI, BioGrid, IntAct, YeastHigh
PSMC3 5702 PRPF40A 55660 pd < reg.ITFP.txt: no annot
ACTB 60 RPA1 6117 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMD14 10213 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB3 5691 PSMD11 5717 pp -- int.I2D: YeastLow
PSMD3 5709 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, INTEROLOG, MINT_Yeast, Krogan_Core, YeastHigh
PSMB7 5695 RPA1 6117 pd < reg.ITFP.txt: no annot
PSMD14 10213 POLR1B 84172 pp -- int.I2D: BioGrid_Yeast
EIF6 3692 DDX51 317781 pd < reg.ITFP.txt: no annot
EIF6 3692 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMD1 5707 PRPF40A 55660 pd < reg.ITFP.txt: no annot
RAN 5901 TREX1 11277 pd < reg.ITFP.txt: no annot
RUVBL2 10856 TREX1 11277 pd <> reg.ITFP.txt: no annot
ACTB 60 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid
PSMA2 5683 PSMA3 5684 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BIND_Yeast, HPRD;
int.HPRD: yeast 2-hybrid
PSMA3 5684 PSMB3 5691 pp -- int.I2D: BioGrid_Yeast, IntAct_Fly, IntAct_Yeast, YeastHigh
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
POLR2F 5435 VARS 7407 pd < reg.ITFP.txt: no annot
ACTB 60 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
EEF2 1938 POLR1B 84172 pp -- int.I2D: YeastLow
PSMA2 5683 PSMB2 5690 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core
EIF6 3692 RUVBL1 8607 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct

Related GO terms (443)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0006521regulation of cellular amino acid metabolic process4.18e-226.83e-186.688122150
GO:0000502proteasome complex3.04e-214.96e-176.473122258
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.36e-202.22e-166.309122465
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1.36e-202.22e-166.309122265
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle3.56e-205.81e-166.202122470
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent6.12e-201.00e-156.142122373
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle7.30e-201.19e-156.122122474
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I1.22e-191.99e-156.065122377
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.69e-192.76e-156.028122579
GO:0002474antigen processing and presentation of peptide antigen via MHC class I1.54e-182.52e-145.777122394
GO:0005654nucleoplasm4.84e-187.90e-143.17323831095
GO:0000082G1/S transition of mitotic cell cycle8.74e-181.43e-135.2181333150
GO:0000209protein polyubiquitination2.15e-173.51e-135.4731221116
GO:0010467gene expression5.80e-179.46e-133.6091958669
GO:0042981regulation of apoptotic process5.56e-169.07e-125.0931226151
GO:0016032viral process8.05e-161.31e-113.7571755540
GO:0034641cellular nitrogen compound metabolic process3.85e-156.28e-114.8641225177
GO:0005839proteasome core complex6.45e-151.05e-107.38471118
GO:0004298threonine-type endopeptidase activity1.57e-142.56e-107.23271120
GO:0016071mRNA metabolic process6.23e-141.02e-094.5311234223
GO:0000278mitotic cell cycle1.19e-131.94e-093.9171452398
GO:0016070RNA metabolic process2.11e-133.45e-094.3831234247
GO:0043066negative regulation of apoptotic process3.76e-136.14e-093.7961430433
GO:0005829cytosol4.29e-137.00e-092.124261252562
GO:0070062extracellular vesicular exosome2.79e-104.55e-061.97323982516
GO:0022624proteasome accessory complex3.16e-105.15e-066.9815917
GO:0044281small molecule metabolic process1.02e-091.67e-052.49517571295
GO:0006915apoptotic process3.53e-095.77e-053.1741234571
GO:0005634nucleus2.45e-084.00e-041.317281314828
GO:0016020membrane9.28e-081.51e-032.06417801746
GO:0019773proteasome core complex, alpha-subunit complex6.47e-071.06e-027.331358
GO:0006281DNA repair2.20e-063.59e-023.509722264
GO:0005730nucleolus2.32e-063.79e-021.93615701684
GO:0005838proteasome regulatory particle2.52e-064.12e-026.7473712
GO:0035267NuA4 histone acetyltransferase complex4.16e-066.80e-026.5243414
GO:0006310DNA recombination1.72e-052.81e-014.6804467
GO:0031465Cul4B-RING E3 ubiquitin ligase complex5.26e-058.58e-017.425225
GO:0016363nuclear matrix6.03e-059.84e-014.22341192
GO:0005515protein binding1.09e-041.00e+000.866261726127
GO:0030529ribonucleoprotein complex1.39e-041.00e+003.91448114
GO:0031464Cul4A-RING E3 ubiquitin ligase complex1.47e-041.00e+006.747228
GO:0000812Swr1 complex1.47e-041.00e+006.747238
GO:0003684damaged DNA binding2.24e-041.00e+004.65931151
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding2.66e-041.00e+004.5773554
GO:0016887ATPase activity3.40e-041.00e+003.57747144
GO:0043968histone H2A acetylation3.43e-041.00e+006.1622312
GO:0030234enzyme regulator activity4.05e-041.00e+006.0462313
GO:0031011Ino80 complex4.72e-041.00e+005.9392314
GO:0006289nucleotide-excision repair5.49e-041.00e+004.22331269
GO:0003697single-stranded DNA binding5.49e-041.00e+004.2233969
GO:0043234protein complex6.20e-041.00e+002.840517300
GO:0042176regulation of protein catabolic process6.21e-041.00e+005.7472316
GO:0006259DNA metabolic process8.80e-041.00e+005.4992319
GO:0003678DNA helicase activity8.80e-041.00e+005.4992319
GO:0006298mismatch repair9.77e-041.00e+005.4252620
GO:0000718nucleotide-excision repair, DNA damage removal1.08e-031.00e+005.3542521
GO:0003924GTPase activity1.23e-031.00e+003.08149203
GO:0043044ATP-dependent chromatin remodeling1.29e-031.00e+005.2232423
GO:0005844polysome1.53e-031.00e+005.1032425
GO:0006184GTP catabolic process1.66e-031.00e+002.96549220
GO:0071339MLL1 complex1.79e-031.00e+004.9922327
GO:0043967histone H4 acetylation1.92e-031.00e+004.9392328
GO:0031492nucleosomal DNA binding1.92e-031.00e+004.9392428
GO:0008380RNA splicing2.01e-031.00e+002.889413232
GO:0006360transcription from RNA polymerase I promoter2.20e-031.00e+004.8402430
GO:0002842positive regulation of T cell mediated immune response to tumor cell2.33e-031.00e+008.747111
GO:0048291isotype switching to IgG isotypes2.33e-031.00e+008.747111
GO:0000972transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery2.33e-031.00e+008.747111
GO:0004088carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity2.33e-031.00e+008.747111
GO:0070335aspartate binding2.33e-031.00e+008.747111
GO:0008541proteasome regulatory particle, lid subcomplex2.33e-031.00e+008.747111
GO:0032558adenyl deoxyribonucleotide binding2.33e-031.00e+008.747111
GO:0022607cellular component assembly2.33e-031.00e+008.747111
GO:0004151dihydroorotase activity2.33e-031.00e+008.747111
GO:0019521D-gluconate metabolic process2.33e-031.00e+008.747111
GO:0000054ribosomal subunit export from nucleus2.33e-031.00e+008.747111
GO:0004070aspartate carbamoyltransferase activity2.33e-031.00e+008.747111
GO:0043973histone H3-K4 acetylation2.33e-031.00e+008.747111
GO:0004486methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity2.33e-031.00e+008.747111
GO:0002368B cell cytokine production2.33e-031.00e+008.747111
GO:0006325chromatin organization2.91e-031.00e+003.38934123
GO:0005524ATP binding3.25e-031.00e+001.5139461354
GO:0000790nuclear chromatin3.62e-031.00e+003.27637133
GO:0032508DNA duplex unwinding4.29e-031.00e+004.3542442
GO:0004832valine-tRNA ligase activity4.65e-031.00e+007.747112
GO:00515383 iron, 4 sulfur cluster binding4.65e-031.00e+007.747112
GO:0003994aconitate hydratase activity4.65e-031.00e+007.747112
GO:0006438valyl-tRNA aminoacylation4.65e-031.00e+007.747112
GO:0000105histidine biosynthetic process4.65e-031.00e+007.747112
GO:00082963'-5'-exodeoxyribonuclease activity4.65e-031.00e+007.747112
GO:0046985positive regulation of hemoglobin biosynthetic process4.65e-031.00e+007.747112
GO:0019322pentose biosynthetic process4.65e-031.00e+007.747112
GO:0070409carbamoyl phosphate biosynthetic process4.65e-031.00e+007.747112
GO:0006283transcription-coupled nucleotide-excision repair5.12e-031.00e+004.2232846
GO:0006200ATP catabolic process5.23e-031.00e+002.503414303
GO:0040008regulation of growth6.26e-031.00e+004.0742351
GO:0000398mRNA splicing, via spliceosome6.60e-031.00e+002.965312165
GO:0005525GTP binding6.90e-031.00e+002.389411328
GO:0004616phosphogluconate dehydrogenase (decarboxylating) activity6.97e-031.00e+007.162113
GO:0071899negative regulation of estrogen receptor binding6.97e-031.00e+007.162113
GO:0006458'de novo' protein folding6.97e-031.00e+007.162113
GO:0071733transcriptional activation by promoter-enhancer looping6.97e-031.00e+007.162113
GO:0000056ribosomal small subunit export from nucleus6.97e-031.00e+007.162113
GO:0009051pentose-phosphate shunt, oxidative branch6.97e-031.00e+007.162113
GO:0030135coated vesicle6.97e-031.00e+007.162113
GO:0044205'de novo' UMP biosynthetic process6.97e-031.00e+007.162113
GO:0006207'de novo' pyrimidine nucleobase biosynthetic process6.97e-031.00e+007.162113
GO:0000932cytoplasmic mRNA processing body7.51e-031.00e+003.9392356
GO:0000724double-strand break repair via homologous recombination7.77e-031.00e+003.9142657
GO:0032481positive regulation of type I interferon production8.86e-031.00e+003.8162661
GO:1901990regulation of mitotic cell cycle phase transition9.28e-031.00e+006.747114
GO:0000212meiotic spindle organization9.28e-031.00e+006.747114
GO:0019788NEDD8 ligase activity9.28e-031.00e+006.747114
GO:0016274protein-arginine N-methyltransferase activity9.28e-031.00e+006.747114
GO:0004488methylenetetrahydrofolate dehydrogenase (NADP+) activity9.28e-031.00e+006.747114
GO:0010669epithelial structure maintenance9.28e-031.00e+006.747114
GO:0032549ribonucleoside binding9.28e-031.00e+006.747124
GO:0004329formate-tetrahydrofolate ligase activity9.28e-031.00e+006.747114
GO:0043141ATP-dependent 5'-3' DNA helicase activity9.28e-031.00e+006.747114
GO:0034969histone arginine methylation9.28e-031.00e+006.747114
GO:0006543glutamine catabolic process9.28e-031.00e+006.747114
GO:0009396folic acid-containing compound biosynthetic process9.28e-031.00e+006.747114
GO:0004477methenyltetrahydrofolate cyclohydrolase activity9.28e-031.00e+006.747114
GO:0031467Cul7-RING ubiquitin ligase complex9.28e-031.00e+006.747114
GO:0000055ribosomal large subunit export from nucleus9.28e-031.00e+006.747114
GO:0008853exodeoxyribonuclease III activity9.28e-031.00e+006.747114
GO:0044822poly(A) RNA binding1.12e-021.00e+001.4807501078
GO:0051414response to cortisol1.16e-021.00e+006.425115
GO:0042256mature ribosome assembly1.16e-021.00e+006.425115
GO:0009086methionine biosynthetic process1.16e-021.00e+006.425115
GO:0032407MutSalpha complex binding1.16e-021.00e+006.425115
GO:0008622epsilon DNA polymerase complex1.16e-021.00e+006.425115
GO:0031461cullin-RING ubiquitin ligase complex1.16e-021.00e+006.425115
GO:0071169establishment of protein localization to chromatin1.16e-021.00e+006.425115
GO:0043248proteasome assembly1.16e-021.00e+006.425115
GO:0046696lipopolysaccharide receptor complex1.16e-021.00e+006.425115
GO:0006102isocitrate metabolic process1.16e-021.00e+006.425115
GO:0030891VCB complex1.16e-021.00e+006.425125
GO:0005827polar microtubule1.16e-021.00e+006.425115
GO:0000730DNA recombinase assembly1.16e-021.00e+006.425135
GO:0005638lamin filament1.16e-021.00e+006.425115
GO:0061133endopeptidase activator activity1.16e-021.00e+006.425115
GO:0005737cytoplasm1.20e-021.00e+000.78916983976
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process1.35e-021.00e+003.4992376
GO:0003688DNA replication origin binding1.39e-021.00e+006.162116
GO:0006101citrate metabolic process1.39e-021.00e+006.162116
GO:0043023ribosomal large subunit binding1.39e-021.00e+006.162126
GO:0031466Cul5-RING ubiquitin ligase complex1.39e-021.00e+006.162116
GO:0030957Tat protein binding1.39e-021.00e+006.162146
GO:0046134pyrimidine nucleoside biosynthetic process1.39e-021.00e+006.162116
GO:0019907cyclin-dependent protein kinase activating kinase holoenzyme complex1.39e-021.00e+006.162116
GO:0032405MutLalpha complex binding1.39e-021.00e+006.162126
GO:0008469histone-arginine N-methyltransferase activity1.39e-021.00e+006.162116
GO:0071013catalytic step 2 spliceosome1.45e-021.00e+003.4432779
GO:0005681spliceosomal complex1.60e-021.00e+003.3712383
GO:0010950positive regulation of endopeptidase activity1.62e-021.00e+005.939117
GO:0070914UV-damage excision repair1.62e-021.00e+005.939117
GO:0002161aminoacyl-tRNA editing activity1.62e-021.00e+005.939127
GO:0035242protein-arginine omega-N asymmetric methyltransferase activity1.62e-021.00e+005.939117
GO:0031462Cul2-RING ubiquitin ligase complex1.62e-021.00e+005.939127
GO:0030274LIM domain binding1.62e-021.00e+005.939117
GO:0035999tetrahydrofolate interconversion1.62e-021.00e+005.939117
GO:0045647negative regulation of erythrocyte differentiation1.62e-021.00e+005.939117
GO:0072341modified amino acid binding1.62e-021.00e+005.939117
GO:0000930gamma-tubulin complex1.62e-021.00e+005.939117
GO:0019919peptidyl-arginine methylation, to asymmetrical-dimethyl arginine1.62e-021.00e+005.939117
GO:0001055RNA polymerase II activity1.85e-021.00e+005.747138
GO:0070688MLL5-L complex1.85e-021.00e+005.747118
GO:0045116protein neddylation1.85e-021.00e+005.747128
GO:0000800lateral element1.85e-021.00e+005.747118
GO:0006164purine nucleotide biosynthetic process1.85e-021.00e+005.747128
GO:0005200structural constituent of cytoskeleton1.98e-021.00e+003.2072793
GO:0051082unfolded protein binding2.06e-021.00e+003.1772695
GO:0014075response to amine2.08e-021.00e+005.577119
GO:0008494translation activator activity2.08e-021.00e+005.577119
GO:0006228UTP biosynthetic process2.08e-021.00e+005.577119
GO:0060322head development2.08e-021.00e+005.577119
GO:0031000response to caffeine2.08e-021.00e+005.577129
GO:0070628proteasome binding2.30e-021.00e+005.4251110
GO:0046655folic acid metabolic process2.30e-021.00e+005.4251110
GO:0006450regulation of translational fidelity2.30e-021.00e+005.4251210
GO:0043032positive regulation of macrophage activation2.30e-021.00e+005.4251110
GO:0051604protein maturation2.30e-021.00e+005.4251110
GO:0006098pentose-phosphate shunt2.53e-021.00e+005.2871311
GO:0032727positive regulation of interferon-alpha production2.53e-021.00e+005.2871111
GO:0001054RNA polymerase I activity2.53e-021.00e+005.2871311
GO:0045120pronucleus2.53e-021.00e+005.2871111
GO:0035518histone H2A monoubiquitination2.53e-021.00e+005.2871211
GO:0035458cellular response to interferon-beta2.53e-021.00e+005.2871211
GO:0061136regulation of proteasomal protein catabolic process2.76e-021.00e+005.1621112
GO:00709353'-UTR-mediated mRNA stabilization2.76e-021.00e+005.1621212
GO:0021702cerebellar Purkinje cell differentiation2.76e-021.00e+005.1621112
GO:0005736DNA-directed RNA polymerase I complex2.76e-021.00e+005.1621312
GO:0032784regulation of DNA-templated transcription, elongation2.76e-021.00e+005.1621112
GO:0042273ribosomal large subunit biogenesis2.99e-021.00e+005.0461413
GO:0032479regulation of type I interferon production2.99e-021.00e+005.0461213
GO:0005662DNA replication factor A complex2.99e-021.00e+005.0461313
GO:0001530lipopolysaccharide binding2.99e-021.00e+005.0461213
GO:0000738DNA catabolic process, exonucleolytic2.99e-021.00e+005.0461213
GO:0008266poly(U) RNA binding2.99e-021.00e+005.0461113
GO:0051131chaperone-mediated protein complex assembly2.99e-021.00e+005.0461113
GO:0080008Cul4-RING E3 ubiquitin ligase complex3.21e-021.00e+004.9391114
GO:0007020microtubule nucleation3.21e-021.00e+004.9391114
GO:0032465regulation of cytokinesis3.21e-021.00e+004.9391114
GO:0006260DNA replication3.42e-021.00e+002.781212125
GO:0035066positive regulation of histone acetylation3.44e-021.00e+004.8401115
GO:0042026protein refolding3.44e-021.00e+004.8401215
GO:0005671Ada2/Gcn5/Ada3 transcription activator complex3.44e-021.00e+004.8401115
GO:0006261DNA-dependent DNA replication3.44e-021.00e+004.8401215
GO:0009948anterior/posterior axis specification3.44e-021.00e+004.8401215
GO:0006511ubiquitin-dependent protein catabolic process3.52e-021.00e+002.75825127
GO:0005665DNA-directed RNA polymerase II, core complex3.66e-021.00e+004.7471416
GO:0050998nitric-oxide synthase binding3.66e-021.00e+004.7471116
GO:0001673male germ cell nucleus3.66e-021.00e+004.7471116
GO:0001056RNA polymerase III activity3.66e-021.00e+004.7471316
GO:00084083'-5' exonuclease activity3.66e-021.00e+004.7471216
GO:0010243response to organonitrogen compound3.89e-021.00e+004.6591217
GO:0005666DNA-directed RNA polymerase III complex3.89e-021.00e+004.6591317
GO:0003746translation elongation factor activity3.89e-021.00e+004.6591317
GO:0075733intracellular transport of virus3.89e-021.00e+004.6591217
GO:0050870positive regulation of T cell activation3.89e-021.00e+004.6591117
GO:0001158enhancer sequence-specific DNA binding3.89e-021.00e+004.6591117
GO:0007126meiotic nuclear division3.89e-021.00e+004.6591117
GO:0070536protein K63-linked deubiquitination4.11e-021.00e+004.5771118
GO:0006386termination of RNA polymerase III transcription4.11e-021.00e+004.5771318
GO:0071392cellular response to estradiol stimulus4.11e-021.00e+004.5771118
GO:0006541glutamine metabolic process4.11e-021.00e+004.5771118
GO:0070064proline-rich region binding4.11e-021.00e+004.5771218
GO:0031122cytoplasmic microtubule organization4.11e-021.00e+004.5771218
GO:0006385transcription elongation from RNA polymerase III promoter4.11e-021.00e+004.5771318
GO:0006303double-strand break repair via nonhomologous end joining4.11e-021.00e+004.5771318
GO:0003682chromatin binding4.23e-021.00e+001.948312334
GO:0016055Wnt signaling pathway4.25e-021.00e+002.60726141
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process4.33e-021.00e+004.4991119
GO:0048863stem cell differentiation4.33e-021.00e+004.4991119
GO:0032733positive regulation of interleukin-10 production4.33e-021.00e+004.4991119
GO:1903506regulation of nucleic acid-templated transcription4.33e-021.00e+004.4991119
GO:0048873homeostasis of number of cells within a tissue4.56e-021.00e+004.4251120
GO:0005719nuclear euchromatin4.56e-021.00e+004.4251220
GO:0006457protein folding4.70e-021.00e+002.52728149
GO:0071364cellular response to epidermal growth factor stimulus4.78e-021.00e+004.3541121
GO:0001702gastrulation with mouth forming second4.78e-021.00e+004.3541221
GO:0006297nucleotide-excision repair, DNA gap filling5.00e-021.00e+004.2871522
GO:0033574response to testosterone5.00e-021.00e+004.2871222
GO:0032201telomere maintenance via semi-conservative replication5.00e-021.00e+004.2871722
GO:0030863cortical cytoskeleton5.00e-021.00e+004.2871122
GO:0036464cytoplasmic ribonucleoprotein granule5.00e-021.00e+004.2871422
GO:0007052mitotic spindle organization5.00e-021.00e+004.2871222
GO:0006362transcription elongation from RNA polymerase I promoter5.22e-021.00e+004.2231323
GO:0031463Cul3-RING ubiquitin ligase complex5.22e-021.00e+004.2231223
GO:0006513protein monoubiquitination5.22e-021.00e+004.2231123
GO:0000794condensed nuclear chromosome5.44e-021.00e+004.1621224
GO:0006206pyrimidine nucleobase metabolic process5.44e-021.00e+004.1621224
GO:0006363termination of RNA polymerase I transcription5.44e-021.00e+004.1621324
GO:0006611protein export from nucleus5.67e-021.00e+004.1031425
GO:0042100B cell proliferation5.67e-021.00e+004.1031125
GO:0003899DNA-directed RNA polymerase activity5.67e-021.00e+004.1031225
GO:0042113B cell activation5.67e-021.00e+004.1031225
GO:0017144drug metabolic process5.67e-021.00e+004.1031125
GO:0032735positive regulation of interleukin-12 production5.67e-021.00e+004.1031125
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding5.82e-021.00e+002.35425168
GO:0006361transcription initiation from RNA polymerase I promoter5.88e-021.00e+004.0461326
GO:0000722telomere maintenance via recombination5.88e-021.00e+004.0461726
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia5.88e-021.00e+004.0461226
GO:0006397mRNA processing5.88e-021.00e+002.34623169
GO:0006730one-carbon metabolic process5.88e-021.00e+004.0461126
GO:0004003ATP-dependent DNA helicase activity6.10e-021.00e+003.9921327
GO:0034080CENP-A containing nucleosome assembly6.10e-021.00e+003.9921227
GO:0016607nuclear speck6.25e-021.00e+002.29524175
GO:0043022ribosome binding6.32e-021.00e+003.9391328
GO:0019894kinesin binding6.32e-021.00e+003.9391128
GO:0003714transcription corepressor activity6.50e-021.00e+002.26327179
GO:0006099tricarboxylic acid cycle6.54e-021.00e+003.8891329
GO:0019005SCF ubiquitin ligase complex6.54e-021.00e+003.8891129
GO:0003730mRNA 3'-UTR binding6.54e-021.00e+003.8891229
GO:0003887DNA-directed DNA polymerase activity6.54e-021.00e+003.8891329
GO:0071897DNA biosynthetic process6.54e-021.00e+003.8891229
GO:00063707-methylguanosine mRNA capping6.76e-021.00e+003.8401430
GO:0015629actin cytoskeleton6.76e-021.00e+002.23125183
GO:0006271DNA strand elongation involved in DNA replication6.98e-021.00e+003.7921931
GO:0050661NADP binding7.19e-021.00e+003.7471132
GO:0031397negative regulation of protein ubiquitination7.19e-021.00e+003.7471132
GO:0034644cellular response to UV7.19e-021.00e+003.7471532
GO:1903507negative regulation of nucleic acid-templated transcription7.19e-021.00e+003.7471232
GO:0001942hair follicle development7.84e-021.00e+003.6171235
GO:0034332adherens junction organization8.06e-021.00e+003.5771136
GO:0004221ubiquitin thiolesterase activity8.06e-021.00e+003.5771236
GO:0001895retina homeostasis8.06e-021.00e+003.5771136
GO:0032755positive regulation of interleukin-6 production8.06e-021.00e+003.5771236
GO:0001102RNA polymerase II activating transcription factor binding8.27e-021.00e+003.5371437
GO:0051084'de novo' posttranslational protein folding8.27e-021.00e+003.5371437
GO:0018107peptidyl-threonine phosphorylation8.27e-021.00e+003.5371137
GO:00515394 iron, 4 sulfur cluster binding8.27e-021.00e+003.5371337
GO:0070527platelet aggregation8.49e-021.00e+003.4991238
GO:0043621protein self-association8.49e-021.00e+003.4991138
GO:0050681androgen receptor binding8.49e-021.00e+003.4991438
GO:0006383transcription from RNA polymerase III promoter8.70e-021.00e+003.4611339
GO:0008026ATP-dependent helicase activity8.70e-021.00e+003.4611339
GO:0031490chromatin DNA binding8.70e-021.00e+003.4611239
GO:0006284base-excision repair8.70e-021.00e+003.4611739
GO:0032729positive regulation of interferon-gamma production8.70e-021.00e+003.4611239
GO:0032092positive regulation of protein binding8.70e-021.00e+003.4611339
GO:0007595lactation8.70e-021.00e+003.4611239
GO:0035019somatic stem cell maintenance8.91e-021.00e+003.4251240
GO:0045785positive regulation of cell adhesion9.13e-021.00e+003.3891541
GO:0043195terminal bouton9.13e-021.00e+003.3891141
GO:0030521androgen receptor signaling pathway9.13e-021.00e+003.3891241
GO:0006418tRNA aminoacylation for protein translation9.34e-021.00e+003.3541542
GO:0005739mitochondrion9.34e-021.00e+001.0385241046
GO:0042110T cell activation9.55e-021.00e+003.3201343
GO:0014070response to organic cyclic compound9.55e-021.00e+003.3201343
GO:0007286spermatid development9.76e-021.00e+003.2871144
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding9.76e-021.00e+003.2871244
GO:0050434positive regulation of viral transcription9.76e-021.00e+003.2871544
GO:0015030Cajal body9.97e-021.00e+003.2551245
GO:0043966histone H3 acetylation9.97e-021.00e+003.2551245
GO:0007067mitotic nuclear division1.01e-011.00e+001.895213231
GO:0021762substantia nigra development1.02e-011.00e+003.2231146
GO:0005759mitochondrial matrix1.02e-011.00e+001.882212233
GO:0045727positive regulation of translation1.02e-011.00e+003.2231446
GO:0042802identical protein binding1.05e-011.00e+001.392318491
GO:0019003GDP binding1.06e-011.00e+003.1621248
GO:0003713transcription coactivator activity1.07e-011.00e+001.846210239
GO:0003743translation initiation factor activity1.08e-011.00e+003.1321449
GO:0031100organ regeneration1.10e-011.00e+003.1031450
GO:0035690cellular response to drug1.10e-011.00e+003.1031250
GO:0006091generation of precursor metabolites and energy1.12e-011.00e+003.0741351
GO:0006986response to unfolded protein1.12e-011.00e+003.0741251
GO:0005905coated pit1.12e-011.00e+003.0741251
GO:0008168methyltransferase activity1.14e-011.00e+003.0461152
GO:0003725double-stranded RNA binding1.18e-011.00e+002.9921654
GO:0090305nucleic acid phosphodiester bond hydrolysis1.18e-011.00e+002.9921254
GO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic process1.18e-011.00e+002.9921154
GO:0000226microtubule cytoskeleton organization1.21e-011.00e+002.9651355
GO:0002039p53 binding1.21e-011.00e+002.9651755
GO:0030097hemopoiesis1.27e-011.00e+002.8891358
GO:0002244hematopoietic progenitor cell differentiation1.27e-011.00e+002.8891158
GO:0008237metallopeptidase activity1.27e-011.00e+002.8891158
GO:0005840ribosome1.29e-011.00e+002.8641259
GO:0051087chaperone binding1.29e-011.00e+002.8641659
GO:0045216cell-cell junction organization1.29e-011.00e+002.8641259
GO:0000723telomere maintenance1.29e-011.00e+002.8641859
GO:0005643nuclear pore1.29e-011.00e+002.8641459
GO:0006302double-strand break repair1.35e-011.00e+002.7921862
GO:0042995cell projection1.37e-011.00e+002.7691663
GO:0019899enzyme binding1.44e-011.00e+001.577211288
GO:0006368transcription elongation from RNA polymerase II promoter1.45e-011.00e+002.6801667
GO:0030141secretory granule1.45e-011.00e+002.6801267
GO:0006338chromatin remodeling1.47e-011.00e+002.6591468
GO:0034329cell junction assembly1.53e-011.00e+002.5971171
GO:0000785chromatin1.57e-011.00e+002.5571573
GO:0055086nucleobase-containing small molecule metabolic process1.57e-011.00e+002.5571573
GO:0006767water-soluble vitamin metabolic process1.61e-011.00e+002.5181375
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis1.65e-011.00e+002.4801577
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process1.65e-011.00e+002.4801677
GO:0030182neuron differentiation1.65e-011.00e+002.4801177
GO:0006766vitamin metabolic process1.67e-011.00e+002.4611378
GO:0006334nucleosome assembly1.69e-011.00e+002.4431479
GO:0002755MyD88-dependent toll-like receptor signaling pathway1.71e-011.00e+002.4251280
GO:0019901protein kinase binding1.71e-011.00e+001.425221320
GO:0007565female pregnancy1.71e-011.00e+002.4251280
GO:0045087innate immune response1.72e-011.00e+001.065320616
GO:0051301cell division1.72e-011.00e+002.4071681
GO:0001889liver development1.74e-011.00e+002.3891382
GO:0005813centrosome1.86e-011.00e+001.341212339
GO:0050821protein stabilization1.92e-011.00e+002.2391291
GO:0003690double-stranded DNA binding1.92e-011.00e+002.2391491
GO:0016605PML body1.94e-011.00e+002.2231592
GO:0042470melanosome1.94e-011.00e+002.22311092
GO:0006928cellular component movement1.94e-011.00e+002.2231792
GO:0006414translational elongation1.95e-011.00e+002.20711193
GO:0001649osteoblast differentiation1.99e-011.00e+002.1771695
GO:0003723RNA binding2.00e-011.00e+001.275219355
GO:0006364rRNA processing2.01e-011.00e+002.1621596
GO:0007010cytoskeleton organization2.01e-011.00e+002.1621296
GO:0071456cellular response to hypoxia2.05e-011.00e+002.1321498
GO:0008360regulation of cell shape2.20e-011.00e+002.01911106
GO:0014069postsynaptic density2.20e-011.00e+002.01911106
GO:0005815microtubule organizing center2.27e-011.00e+001.96514110
GO:0015630microtubule cytoskeleton2.30e-011.00e+001.93915112
GO:0019058viral life cycle2.36e-011.00e+001.901110115
GO:0005635nuclear envelope2.38e-011.00e+001.88916116
GO:0072562blood microparticle2.38e-011.00e+001.88914116
GO:0044237cellular metabolic process2.41e-011.00e+001.86413118
GO:0046872metal ion binding2.52e-011.00e+000.5525241465
GO:0007219Notch signaling pathway2.54e-011.00e+001.78114125
GO:0005506iron ion binding2.57e-011.00e+001.75813127
GO:0006366transcription from RNA polymerase II promoter2.60e-011.00e+001.015212425
GO:0006413translational initiation2.64e-011.00e+001.713112131
GO:0016477cell migration2.64e-011.00e+001.71316131
GO:0009615response to virus2.66e-011.00e+001.70216132
GO:0000086G2/M transition of mitotic cell cycle2.74e-011.00e+001.64817137
GO:0007507heart development2.81e-011.00e+001.60715141
GO:0061024membrane organization2.90e-011.00e+001.55715146
GO:0010628positive regulation of gene expression2.95e-011.00e+001.52714149
GO:0005769early endosome3.09e-011.00e+001.44312158
GO:0046777protein autophosphorylation3.09e-011.00e+001.44313158
GO:0055114oxidation-reduction process3.09e-011.00e+000.837211481
GO:0044267cellular protein metabolic process3.21e-011.00e+000.795224495
GO:0030424axon3.32e-011.00e+001.32013172
GO:0007049cell cycle3.40e-011.00e+001.27913177
GO:0004672protein kinase activity3.41e-011.00e+001.27112178
GO:0005667transcription factor complex3.41e-011.00e+001.27116178
GO:0031625ubiquitin protein ligase binding3.44e-011.00e+001.255113180
GO:0019904protein domain specific binding3.46e-011.00e+001.24716181
GO:0006367transcription initiation from RNA polymerase II promoter3.50e-011.00e+001.22318184
GO:0032403protein complex binding3.52e-011.00e+001.21517185
GO:0001701in utero embryonic development3.89e-011.00e+001.03216210
GO:0005622intracellular4.12e-011.00e+000.92615226
GO:0005615extracellular space4.21e-011.00e+000.3513171010
GO:0042803protein homodimerization activity4.24e-011.00e+000.477211617
GO:0006412translation4.24e-011.00e+000.870115235
GO:0043025neuronal cell body4.49e-011.00e+000.75814254
GO:0005794Golgi apparatus4.50e-011.00e+000.402214650
GO:0004842ubiquitin-protein transferase activity4.52e-011.00e+000.74714256
GO:0000166nucleotide binding4.72e-011.00e+000.65916272
GO:0005975carbohydrate metabolic process4.75e-011.00e+000.64815274
GO:0043065positive regulation of apoptotic process4.75e-011.00e+000.64818274
GO:0006357regulation of transcription from RNA polymerase II promoter4.76e-011.00e+000.64316275
GO:0007283spermatogenesis4.77e-011.00e+000.63816276
GO:0007264small GTPase mediated signal transduction4.94e-011.00e+000.56713290
GO:0016567protein ubiquitination5.05e-011.00e+000.52315299
GO:0005743mitochondrial inner membrane5.06e-011.00e+000.51815300
GO:0005856cytoskeleton5.19e-011.00e+000.46618311
GO:0007411axon guidance5.37e-011.00e+000.39319327
GO:0043231intracellular membrane-bounded organelle5.42e-011.00e+000.37118332
GO:0007275multicellular organismal development5.55e-011.00e+000.32015344
GO:0045944positive regulation of transcription from RNA polymerase II promoter5.70e-011.00e+000.083219811
GO:0043565sequence-specific DNA binding5.77e-011.00e+000.23514365
GO:0005925focal adhesion5.82e-011.00e+000.215118370
GO:0008284positive regulation of cell proliferation6.03e-011.00e+000.13218392
GO:0046982protein heterodimerization activity6.10e-011.00e+000.106111399
GO:0003677DNA binding6.19e-011.00e+00-0.0683261351
GO:0009986cell surface6.31e-011.00e+000.02519422
GO:0045892negative regulation of transcription, DNA-templated6.33e-011.00e+000.019114424
GO:0007596blood coagulation6.66e-011.00e+00-0.111114464
GO:0045893positive regulation of transcription, DNA-templated6.84e-011.00e+00-0.181117487
GO:0008270zinc ion binding7.20e-011.00e+00-0.3132121067
GO:0006351transcription, DNA-templated7.28e-011.00e+00-0.2993251585
GO:0006355regulation of transcription, DNA-templated7.38e-011.00e+00-0.3622171104
GO:0005789endoplasmic reticulum membrane7.80e-011.00e+00-0.566110636
GO:0007165signal transduction8.98e-011.00e+00-1.145117950
GO:0005886plasma membrane9.99e-011.00e+00-2.7221382834