reg-snw-55660

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.830	8.54e-07	2.78e-03	5.31e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-55660 subnetwork

Genes (6)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
PSMA1	5682	5	0.996	0.878	29	-	Yes	-
PSMD11	5717	15	1.095	0.940	35	TF	Yes	-
PSMD1	5707	2	0.836	0.830	5	-	Yes	-
HSPD1	3329	4	0.913	0.875	39	-	Yes	-
PSMC3	5702	3	0.719	0.830	21	-	Yes	-
[ PRPF40A ]	55660	1	0.423	0.830	106	TF	Yes	-

Interactions (5)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PSMD1	5707	PRPF40A	55660	pd	<	reg.ITFP.txt: no annot
HSPD1	3329	PRPF40A	55660	pd	<	reg.ITFP.txt: no annot
PSMC3	5702	PSMD11	5717	pd	<	reg.ITFP.txt: no annot
PSMC3	5702	PRPF40A	55660	pd	<	reg.ITFP.txt: no annot
PSMA1	5682	PRPF40A	55660	pd	<	reg.ITFP.txt: no annot

Related GO terms (105)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006521	regulation of cellular amino acid metabolic process	3.99e-09	3.89e-05	7.311	4	16	41
GO:0000502	proteasome complex	7.02e-09	6.85e-05	7.114	4	17	47
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.06e-08	1.04e-04	6.968	4	17	52
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	1.15e-08	1.12e-04	6.941	4	17	53
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.44e-08	1.41e-04	6.861	4	17	56
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	1.55e-08	1.51e-04	6.836	4	16	57
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.91e-08	1.87e-04	6.762	4	17	60
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	2.05e-08	2.00e-04	6.738	4	16	61
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	2.66e-08	2.59e-04	6.646	4	17	65
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	3.59e-08	3.51e-04	6.539	4	16	70
GO:0022624	proteasome accessory complex	4.68e-08	4.57e-04	8.446	3	7	14
GO:0000209	protein polyubiquitination	1.09e-07	1.07e-03	6.145	4	16	92
GO:0034641	cellular nitrogen compound metabolic process	1.86e-07	1.82e-03	5.954	4	18	105
GO:0043066	negative regulation of apoptotic process	2.21e-07	2.16e-03	4.659	5	20	322
GO:0042981	regulation of apoptotic process	2.42e-07	2.36e-03	5.861	4	18	112
GO:0000082	G1/S transition of mitotic cell cycle	3.76e-07	3.68e-03	5.703	4	24	125
GO:0016032	viral process	9.15e-07	8.93e-03	4.249	5	32	428
GO:0016071	mRNA metabolic process	1.29e-06	1.26e-02	5.259	4	21	170
GO:0016070	RNA metabolic process	1.94e-06	1.89e-02	5.114	4	21	188
GO:0005838	proteasome regulatory particle	1.41e-05	1.38e-01	8.347	2	4	10
GO:0000278	mitotic cell cycle	1.50e-05	1.46e-01	4.374	4	35	314
GO:0006915	apoptotic process	4.34e-05	4.24e-01	3.985	4	21	411
GO:0010467	gene expression	1.22e-04	1.00e+00	3.605	4	31	535
GO:0016020	membrane	1.54e-04	1.00e+00	2.753	5	38	1207
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	6.14e-04	1.00e+00	10.668	1	1	1
GO:0048291	isotype switching to IgG isotypes	6.14e-04	1.00e+00	10.668	1	1	1
GO:0002368	B cell cytokine production	6.14e-04	1.00e+00	10.668	1	1	1
GO:0044281	small molecule metabolic process	7.21e-04	1.00e+00	2.947	4	32	844
GO:0005654	nucleoplasm	8.33e-04	1.00e+00	2.894	4	55	876
GO:0005829	cytosol	1.04e-03	1.00e+00	2.187	5	58	1787
GO:0006458	'de novo' protein folding	1.23e-03	1.00e+00	9.668	1	1	2
GO:0016887	ATPase activity	1.52e-03	1.00e+00	5.025	2	6	100
GO:0003688	DNA replication origin binding	1.84e-03	1.00e+00	9.083	1	1	3
GO:0030135	coated vesicle	1.84e-03	1.00e+00	9.083	1	1	3
GO:0046696	lipopolysaccharide receptor complex	1.84e-03	1.00e+00	9.083	1	1	3
GO:0043248	proteasome assembly	2.46e-03	1.00e+00	8.668	1	1	4
GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex	3.07e-03	1.00e+00	8.347	1	1	5
GO:0019773	proteasome core complex, alpha-subunit complex	3.68e-03	1.00e+00	8.083	1	4	6
GO:0043032	positive regulation of macrophage activation	3.68e-03	1.00e+00	8.083	1	1	6
GO:0032727	positive regulation of interferon-alpha production	4.91e-03	1.00e+00	7.668	1	1	8
GO:0051604	protein maturation	4.91e-03	1.00e+00	7.668	1	1	8
GO:0001530	lipopolysaccharide binding	5.52e-03	1.00e+00	7.499	1	1	9
GO:0042026	protein refolding	6.13e-03	1.00e+00	7.347	1	1	10
GO:0032465	regulation of cytokinesis	6.13e-03	1.00e+00	7.347	1	1	10
GO:0051131	chaperone-mediated protein complex assembly	6.13e-03	1.00e+00	7.347	1	1	10
GO:0030234	enzyme regulator activity	6.74e-03	1.00e+00	7.209	1	2	11
GO:0006200	ATP catabolic process	7.08e-03	1.00e+00	3.894	2	8	219
GO:0048863	stem cell differentiation	7.35e-03	1.00e+00	7.083	1	1	12
GO:0032733	positive regulation of interleukin-10 production	7.96e-03	1.00e+00	6.968	1	1	13
GO:0042176	regulation of protein catabolic process	8.57e-03	1.00e+00	6.861	1	2	14
GO:0070064	proline-rich region binding	8.57e-03	1.00e+00	6.861	1	1	14
GO:0050870	positive regulation of T cell activation	8.57e-03	1.00e+00	6.861	1	1	14
GO:0070062	extracellular vesicular exosome	8.95e-03	1.00e+00	1.988	4	43	1641
GO:1903506	regulation of nucleic acid-templated transcription	9.79e-03	1.00e+00	6.668	1	1	16
GO:0042113	B cell activation	9.79e-03	1.00e+00	6.668	1	1	16
GO:0005839	proteasome core complex	9.79e-03	1.00e+00	6.668	1	9	16
GO:0042100	B cell proliferation	1.04e-02	1.00e+00	6.581	1	1	17
GO:0004298	threonine-type endopeptidase activity	1.04e-02	1.00e+00	6.581	1	9	17
GO:0005844	polysome	1.16e-02	1.00e+00	6.421	1	1	19
GO:0032735	positive regulation of interleukin-12 production	1.22e-02	1.00e+00	6.347	1	1	20
GO:1903507	negative regulation of nucleic acid-templated transcription	1.28e-02	1.00e+00	6.276	1	1	21
GO:0032755	positive regulation of interleukin-6 production	1.65e-02	1.00e+00	5.914	1	1	27
GO:0032729	positive regulation of interferon-gamma production	1.71e-02	1.00e+00	5.861	1	1	28
GO:0042110	T cell activation	2.01e-02	1.00e+00	5.624	1	1	33
GO:0006986	response to unfolded protein	2.13e-02	1.00e+00	5.539	1	1	35
GO:0005905	coated pit	2.25e-02	1.00e+00	5.459	1	2	37
GO:0000932	cytoplasmic mRNA processing body	2.61e-02	1.00e+00	5.242	1	2	43
GO:0030141	secretory granule	2.67e-02	1.00e+00	5.209	1	1	44
GO:0051087	chaperone binding	2.73e-02	1.00e+00	5.177	1	3	45
GO:0003725	double-stranded RNA binding	2.73e-02	1.00e+00	5.177	1	3	45
GO:0002039	p53 binding	2.73e-02	1.00e+00	5.177	1	2	45
GO:0051301	cell division	2.97e-02	1.00e+00	5.054	1	3	49
GO:0003697	single-stranded DNA binding	3.45e-02	1.00e+00	4.836	1	6	57
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	3.69e-02	1.00e+00	4.738	1	1	61
GO:0007010	cytoskeleton organization	3.69e-02	1.00e+00	4.738	1	1	61
GO:0050821	protein stabilization	3.87e-02	1.00e+00	4.668	1	1	64
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	4.05e-02	1.00e+00	4.602	1	2	67
GO:0008360	regulation of cell shape	4.23e-02	1.00e+00	4.539	1	1	70
GO:0051082	unfolded protein binding	4.23e-02	1.00e+00	4.539	1	4	70
GO:0016363	nuclear matrix	4.40e-02	1.00e+00	4.479	1	7	73
GO:0005515	protein binding	5.22e-02	1.00e+00	0.981	5	76	4124
GO:0006511	ubiquitin-dependent protein catabolic process	5.52e-02	1.00e+00	4.145	1	2	92
GO:0016477	cell migration	5.76e-02	1.00e+00	4.083	1	2	96
GO:0005769	early endosome	6.51e-02	1.00e+00	3.900	1	1	109
GO:0006397	mRNA processing	6.57e-02	1.00e+00	3.887	1	2	110
GO:0007049	cell cycle	6.86e-02	1.00e+00	3.823	1	3	115
GO:0016607	nuclear speck	7.27e-02	1.00e+00	3.738	1	3	122
GO:0044822	poly(A) RNA binding	8.04e-02	1.00e+00	2.026	2	25	799
GO:0003714	transcription corepressor activity	8.13e-02	1.00e+00	3.570	1	2	137
GO:0005759	mitochondrial matrix	8.24e-02	1.00e+00	3.550	1	5	139
GO:0008380	RNA splicing	9.72e-02	1.00e+00	3.302	1	7	165
GO:0005524	ATP binding	9.76e-02	1.00e+00	1.868	2	23	892
GO:0005634	nucleus	9.92e-02	1.00e+00	1.004	4	67	3246
GO:0003713	transcription coactivator activity	1.08e-01	1.00e+00	3.145	1	5	184
GO:0005743	mitochondrial inner membrane	1.15e-01	1.00e+00	3.046	1	3	197
GO:0043065	positive regulation of apoptotic process	1.18e-01	1.00e+00	3.010	1	3	202
GO:0043234	protein complex	1.22e-01	1.00e+00	2.954	1	8	210
GO:0005813	centrosome	1.26e-01	1.00e+00	2.907	1	8	217
GO:0003723	RNA binding	1.43e-01	1.00e+00	2.720	1	11	247
GO:0005730	nucleolus	1.66e-01	1.00e+00	1.419	2	41	1217
GO:0009986	cell surface	1.66e-01	1.00e+00	2.484	1	2	291
GO:0005615	extracellular space	3.39e-01	1.00e+00	1.322	1	8	651
GO:0005739	mitochondrion	3.43e-01	1.00e+00	1.304	1	11	659
GO:0005737	cytoplasm	5.12e-01	1.00e+00	0.306	2	50	2633
GO:0005886	plasma membrane	7.02e-01	1.00e+00	-0.132	1	11	1784

Wolf-ratios-Mammosphere-Adherent

reg-snw-55660

Statistics

Genes (6)

Interactions (5)

Related GO terms (105)