Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
wolf-screen-ratio-mammosphere-adherent | 0.937 | 1.33e-15 | 2.35e-03 | 3.86e-02 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
ACO2 | 50 | 50 | 1.000 | 1.076 | 191 | Yes | - |
EEF2 | 1938 | 27 | 0.890 | 1.043 | 301 | Yes | - |
PSMA2 | 5683 | 60 | 1.093 | 1.106 | 89 | Yes | - |
PSMD3 | 5709 | 57 | 0.986 | 1.106 | 146 | Yes | - |
[ LDB1 ] | 8861 | 1 | 0.385 | 0.937 | 45 | Yes | - |
PSMB7 | 5695 | 48 | 0.982 | 1.052 | 57 | Yes | - |
PSMB2 | 5690 | 18 | 0.877 | 1.026 | 117 | Yes | - |
PSMA1 | 5682 | 61 | 0.996 | 1.052 | 123 | Yes | - |
ACTB | 60 | 167 | 1.153 | 1.151 | 587 | Yes | - |
PSMD11 | 5717 | 121 | 1.095 | 1.106 | 183 | Yes | - |
POLR1B | 84172 | 4 | 0.613 | 0.988 | 184 | Yes | - |
HSPD1 | 3329 | 35 | 0.913 | 1.035 | 286 | Yes | - |
PGD | 5226 | 75 | 1.201 | 1.106 | 138 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
PGD | 5226 | POLR1B | 84172 | pp | -- | int.I2D: YeastLow |
HSPD1 | 3329 | POLR1B | 84172 | pp | -- | int.I2D: YeastLow |
ACTB | 60 | PSMB2 | 5690 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA1 | 5682 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
PSMD3 | 5709 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG |
PSMD3 | 5709 | POLR1B | 84172 | pp | -- | int.I2D: IntAct_Yeast, YeastLow |
ACTB | 60 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA1 | 5682 | PSMA2 | 5683 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid |
EEF2 | 1938 | PGD | 5226 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA1 | 5682 | LDB1 | 8861 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: VidalHuman_non_core |
PSMB2 | 5690 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct |
ACTB | 60 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | POLR1B | 84172 | pp | -- | int.I2D: BIND, BIND_Mouse |
PSMB2 | 5690 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMA2 | 5683 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast |
PGD | 5226 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
PSMD11 | 5717 | POLR1B | 84172 | pp | -- | int.I2D: YeastLow |
ACTB | 60 | PSMA1 | 5682 | pp | -- | int.I2D: BioGrid_Yeast |
ACO2 | 50 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
EEF2 | 1938 | HSPD1 | 3329 | pp | -- | int.I2D: YeastLow, YeastMedium |
PSMA2 | 5683 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
ACTB | 60 | EEF2 | 1938 | pp | -- | int.I2D: YeastLow, IntAct_Yeast |
PSMA1 | 5682 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
EEF2 | 1938 | POLR1B | 84172 | pp | -- | int.I2D: YeastLow |
PGD | 5226 | PSMD3 | 5709 | pp | -- | int.I2D: YeastLow |
ACO2 | 50 | POLR1B | 84172 | pp | -- | int.I2D: YeastLow |
PSMA2 | 5683 | PSMB2 | 5690 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core |
LDB1 | 8861 | POLR1B | 84172 | pp | -- | int.Intact: MI:0915(physical association) |
ACO2 | 50 | PGD | 5226 | pp | -- | int.I2D: YeastLow |
ACO2 | 50 | HSPD1 | 3329 | pp | -- | int.I2D: IntAct_Yeast |
PSMA1 | 5682 | PSMB2 | 5690 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid |
PSMA2 | 5683 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMA1 | 5682 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast |
ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB7 | 5695 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB2 | 5690 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
EEF2 | 1938 | PSMD3 | 5709 | pp | -- | int.I2D: Krogan_NonCore |
ACTB | 60 | HSPD1 | 3329 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct, YeastLow |
PSMB7 | 5695 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0006521 | regulation of cellular amino acid metabolic process | 2.14e-12 | 3.09e-08 | 7.057 | 6 | 17 | 50 |
GO:0000502 | proteasome complex | 5.44e-12 | 7.85e-08 | 6.843 | 6 | 17 | 58 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 1.01e-11 | 1.45e-07 | 6.701 | 6 | 19 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.11e-11 | 1.60e-07 | 6.678 | 6 | 22 | 65 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.75e-11 | 2.53e-07 | 6.571 | 6 | 22 | 70 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 2.09e-11 | 3.01e-07 | 6.531 | 6 | 20 | 72 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 2.47e-11 | 3.57e-07 | 6.491 | 6 | 22 | 74 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 2.69e-11 | 3.88e-07 | 6.472 | 6 | 20 | 75 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 3.70e-11 | 5.34e-07 | 6.397 | 6 | 23 | 79 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 9.45e-11 | 1.36e-06 | 6.177 | 6 | 21 | 92 |
GO:0000209 | protein polyubiquitination | 3.89e-10 | 5.62e-06 | 5.843 | 6 | 20 | 116 |
GO:0005839 | proteasome core complex | 1.21e-09 | 1.74e-05 | 7.946 | 4 | 8 | 18 |
GO:0004298 | threonine-type endopeptidase activity | 1.53e-09 | 2.20e-05 | 7.868 | 4 | 8 | 19 |
GO:0000082 | G1/S transition of mitotic cell cycle | 1.78e-09 | 2.56e-05 | 5.481 | 6 | 32 | 149 |
GO:0042981 | regulation of apoptotic process | 1.85e-09 | 2.67e-05 | 5.472 | 6 | 24 | 150 |
GO:0034641 | cellular nitrogen compound metabolic process | 4.08e-09 | 5.88e-05 | 5.283 | 6 | 20 | 171 |
GO:0016071 | mRNA metabolic process | 2.00e-08 | 2.89e-04 | 4.900 | 6 | 31 | 223 |
GO:0010467 | gene expression | 2.15e-08 | 3.10e-04 | 3.730 | 8 | 59 | 669 |
GO:0043066 | negative regulation of apoptotic process | 2.66e-08 | 3.84e-04 | 4.195 | 7 | 31 | 424 |
GO:0016070 | RNA metabolic process | 3.68e-08 | 5.31e-04 | 4.752 | 6 | 32 | 247 |
GO:0016032 | viral process | 1.30e-07 | 1.87e-03 | 3.862 | 7 | 55 | 534 |
GO:0000278 | mitotic cell cycle | 5.58e-07 | 8.05e-03 | 4.090 | 6 | 48 | 391 |
GO:0005654 | nucleoplasm | 8.95e-07 | 1.29e-02 | 3.036 | 8 | 76 | 1082 |
GO:0044281 | small molecule metabolic process | 2.12e-06 | 3.06e-02 | 2.874 | 8 | 58 | 1211 |
GO:0070062 | extracellular vesicular exosome | 2.81e-06 | 4.05e-02 | 2.209 | 10 | 104 | 2400 |
GO:0005829 | cytosol | 4.07e-06 | 5.87e-02 | 2.152 | 10 | 132 | 2496 |
GO:0006915 | apoptotic process | 4.30e-06 | 6.21e-02 | 3.584 | 6 | 33 | 555 |
GO:0019773 | proteasome core complex, alpha-subunit complex | 2.09e-05 | 3.02e-01 | 8.116 | 2 | 4 | 8 |
GO:0005838 | proteasome regulatory particle | 4.92e-05 | 7.10e-01 | 7.531 | 2 | 7 | 12 |
GO:0022624 | proteasome accessory complex | 1.01e-04 | 1.00e+00 | 7.028 | 2 | 8 | 17 |
GO:0005844 | polysome | 1.88e-04 | 1.00e+00 | 6.592 | 2 | 4 | 23 |
GO:0002842 | positive regulation of T cell mediated immune response to tumor cell | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:0022607 | cellular component assembly | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:0048291 | isotype switching to IgG isotypes | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:0019521 | D-gluconate metabolic process | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:0043973 | histone H3-K4 acetylation | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:0002368 | B cell cytokine production | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:0005634 | nucleus | 1.03e-03 | 1.00e+00 | 1.283 | 10 | 136 | 4559 |
GO:0051538 | 3 iron, 4 sulfur cluster binding | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0046985 | positive regulation of hemoglobin biosynthetic process | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0019322 | pentose biosynthetic process | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 2 | 2 |
GO:0003994 | aconitate hydratase activity | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0016020 | membrane | 2.06e-03 | 1.00e+00 | 1.986 | 6 | 90 | 1681 |
GO:0043234 | protein complex | 2.08e-03 | 1.00e+00 | 3.496 | 3 | 18 | 295 |
GO:0006458 | 'de novo' protein folding | 2.70e-03 | 1.00e+00 | 8.531 | 1 | 1 | 3 |
GO:0009051 | pentose-phosphate shunt, oxidative branch | 2.70e-03 | 1.00e+00 | 8.531 | 1 | 2 | 3 |
GO:0030135 | coated vesicle | 2.70e-03 | 1.00e+00 | 8.531 | 1 | 1 | 3 |
GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity | 2.70e-03 | 1.00e+00 | 8.531 | 1 | 1 | 3 |
GO:0010669 | epithelial structure maintenance | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 1 | 4 |
GO:0032549 | ribonucleoside binding | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 2 | 4 |
GO:0030529 | ribonucleoprotein complex | 4.41e-03 | 1.00e+00 | 4.308 | 2 | 8 | 112 |
GO:0043248 | proteasome assembly | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 |
GO:0046696 | lipopolysaccharide receptor complex | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 |
GO:0006102 | isocitrate metabolic process | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 |
GO:0003688 | DNA replication origin binding | 5.40e-03 | 1.00e+00 | 7.531 | 1 | 2 | 6 |
GO:0030957 | Tat protein binding | 5.40e-03 | 1.00e+00 | 7.531 | 1 | 3 | 6 |
GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex | 5.40e-03 | 1.00e+00 | 7.531 | 1 | 1 | 6 |
GO:0006101 | citrate metabolic process | 5.40e-03 | 1.00e+00 | 7.531 | 1 | 1 | 6 |
GO:0000790 | nuclear chromatin | 5.80e-03 | 1.00e+00 | 4.104 | 2 | 9 | 129 |
GO:0030274 | LIM domain binding | 6.29e-03 | 1.00e+00 | 7.308 | 1 | 1 | 7 |
GO:0045647 | negative regulation of erythrocyte differentiation | 6.29e-03 | 1.00e+00 | 7.308 | 1 | 1 | 7 |
GO:0070688 | MLL5-L complex | 7.19e-03 | 1.00e+00 | 7.116 | 1 | 1 | 8 |
GO:0051604 | protein maturation | 7.19e-03 | 1.00e+00 | 7.116 | 1 | 1 | 8 |
GO:0060322 | head development | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 1 | 9 |
GO:0008494 | translation activator activity | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 1 | 9 |
GO:0006098 | pentose-phosphate shunt | 8.98e-03 | 1.00e+00 | 6.794 | 1 | 4 | 10 |
GO:0043032 | positive regulation of macrophage activation | 8.98e-03 | 1.00e+00 | 6.794 | 1 | 1 | 10 |
GO:0032727 | positive regulation of interferon-alpha production | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 1 | 11 |
GO:0032784 | regulation of DNA-templated transcription, elongation | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 1 | 12 |
GO:0021702 | cerebellar Purkinje cell differentiation | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 1 | 12 |
GO:0005730 | nucleolus | 1.11e-02 | 1.00e+00 | 1.757 | 5 | 69 | 1641 |
GO:0030234 | enzyme regulator activity | 1.17e-02 | 1.00e+00 | 6.415 | 1 | 3 | 13 |
GO:0001530 | lipopolysaccharide binding | 1.17e-02 | 1.00e+00 | 6.415 | 1 | 3 | 13 |
GO:0051131 | chaperone-mediated protein complex assembly | 1.17e-02 | 1.00e+00 | 6.415 | 1 | 1 | 13 |
GO:0035267 | NuA4 histone acetyltransferase complex | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 4 | 14 |
GO:0009948 | anterior/posterior axis specification | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 2 | 14 |
GO:0042026 | protein refolding | 1.34e-02 | 1.00e+00 | 6.209 | 1 | 2 | 15 |
GO:0050998 | nitric-oxide synthase binding | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 1 | 16 |
GO:0042176 | regulation of protein catabolic process | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 3 | 16 |
GO:0001158 | enhancer sequence-specific DNA binding | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 1 | 16 |
GO:0010243 | response to organonitrogen compound | 1.52e-02 | 1.00e+00 | 6.028 | 1 | 3 | 17 |
GO:0050870 | positive regulation of T cell activation | 1.52e-02 | 1.00e+00 | 6.028 | 1 | 1 | 17 |
GO:0003746 | translation elongation factor activity | 1.52e-02 | 1.00e+00 | 6.028 | 1 | 3 | 17 |
GO:0032733 | positive regulation of interleukin-10 production | 1.70e-02 | 1.00e+00 | 5.868 | 1 | 1 | 19 |
GO:0048863 | stem cell differentiation | 1.70e-02 | 1.00e+00 | 5.868 | 1 | 1 | 19 |
GO:0005759 | mitochondrial matrix | 1.73e-02 | 1.00e+00 | 3.283 | 2 | 14 | 228 |
GO:0042100 | B cell proliferation | 1.88e-02 | 1.00e+00 | 5.723 | 1 | 1 | 21 |
GO:0001702 | gastrulation with mouth forming second | 1.88e-02 | 1.00e+00 | 5.723 | 1 | 2 | 21 |
GO:0030863 | cortical cytoskeleton | 1.97e-02 | 1.00e+00 | 5.656 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 1.97e-02 | 1.00e+00 | 5.656 | 1 | 4 | 22 |
GO:0043044 | ATP-dependent chromatin remodeling | 2.05e-02 | 1.00e+00 | 5.592 | 1 | 4 | 23 |
GO:0006362 | transcription elongation from RNA polymerase I promoter | 2.05e-02 | 1.00e+00 | 5.592 | 1 | 3 | 23 |
GO:0006363 | termination of RNA polymerase I transcription | 2.14e-02 | 1.00e+00 | 5.531 | 1 | 3 | 24 |
GO:0003899 | DNA-directed RNA polymerase activity | 2.23e-02 | 1.00e+00 | 5.472 | 1 | 3 | 25 |
GO:0042113 | B cell activation | 2.23e-02 | 1.00e+00 | 5.472 | 1 | 2 | 25 |
GO:0032735 | positive regulation of interleukin-12 production | 2.23e-02 | 1.00e+00 | 5.472 | 1 | 1 | 25 |
GO:0006361 | transcription initiation from RNA polymerase I promoter | 2.32e-02 | 1.00e+00 | 5.415 | 1 | 3 | 26 |
GO:0050661 | NADP binding | 2.41e-02 | 1.00e+00 | 5.361 | 1 | 2 | 27 |
GO:0031492 | nucleosomal DNA binding | 2.41e-02 | 1.00e+00 | 5.361 | 1 | 4 | 27 |
GO:0006099 | tricarboxylic acid cycle | 2.50e-02 | 1.00e+00 | 5.308 | 1 | 4 | 28 |
GO:0019894 | kinesin binding | 2.50e-02 | 1.00e+00 | 5.308 | 1 | 1 | 28 |
GO:0006360 | transcription from RNA polymerase I promoter | 2.67e-02 | 1.00e+00 | 5.209 | 1 | 5 | 30 |
GO:0001895 | retina homeostasis | 3.02e-02 | 1.00e+00 | 5.028 | 1 | 1 | 34 |
GO:0001942 | hair follicle development | 3.11e-02 | 1.00e+00 | 4.986 | 1 | 1 | 35 |
GO:0051539 | 4 iron, 4 sulfur cluster binding | 3.11e-02 | 1.00e+00 | 4.986 | 1 | 3 | 35 |
GO:0034332 | adherens junction organization | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 1 | 36 |
GO:0019901 | protein kinase binding | 3.20e-02 | 1.00e+00 | 2.807 | 2 | 21 | 317 |
GO:0001102 | RNA polymerase II activating transcription factor binding | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 2 | 36 |
GO:0043621 | protein self-association | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 2 | 36 |
GO:0032755 | positive regulation of interleukin-6 production | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 2 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 3.29e-02 | 1.00e+00 | 4.906 | 1 | 4 | 37 |
GO:0070527 | platelet aggregation | 3.37e-02 | 1.00e+00 | 4.868 | 1 | 2 | 38 |
GO:0032729 | positive regulation of interferon-gamma production | 3.46e-02 | 1.00e+00 | 4.830 | 1 | 2 | 39 |
GO:0035019 | somatic stem cell maintenance | 3.55e-02 | 1.00e+00 | 4.794 | 1 | 1 | 40 |
GO:0045785 | positive regulation of cell adhesion | 3.55e-02 | 1.00e+00 | 4.794 | 1 | 4 | 40 |
GO:0042110 | T cell activation | 3.72e-02 | 1.00e+00 | 4.723 | 1 | 3 | 42 |
GO:0014070 | response to organic cyclic compound | 3.81e-02 | 1.00e+00 | 4.689 | 1 | 4 | 43 |
GO:0021762 | substantia nigra development | 3.90e-02 | 1.00e+00 | 4.656 | 1 | 2 | 44 |
GO:0045727 | positive regulation of translation | 3.90e-02 | 1.00e+00 | 4.656 | 1 | 3 | 44 |
GO:0005515 | protein binding | 4.29e-02 | 1.00e+00 | 0.729 | 9 | 184 | 6024 |
GO:0006091 | generation of precursor metabolites and energy | 4.42e-02 | 1.00e+00 | 4.472 | 1 | 3 | 50 |
GO:0006986 | response to unfolded protein | 4.42e-02 | 1.00e+00 | 4.472 | 1 | 2 | 50 |
GO:0005905 | coated pit | 4.42e-02 | 1.00e+00 | 4.472 | 1 | 3 | 50 |
GO:0003725 | double-stranded RNA binding | 4.59e-02 | 1.00e+00 | 4.415 | 1 | 5 | 52 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 4.68e-02 | 1.00e+00 | 4.388 | 1 | 5 | 53 |
GO:0002244 | hematopoietic progenitor cell differentiation | 4.76e-02 | 1.00e+00 | 4.361 | 1 | 1 | 54 |
GO:0045216 | cell-cell junction organization | 4.76e-02 | 1.00e+00 | 4.361 | 1 | 2 | 54 |
GO:0000932 | cytoplasmic mRNA processing body | 4.76e-02 | 1.00e+00 | 4.361 | 1 | 3 | 54 |
GO:0002039 | p53 binding | 4.85e-02 | 1.00e+00 | 4.334 | 1 | 7 | 55 |
GO:0051087 | chaperone binding | 5.19e-02 | 1.00e+00 | 4.233 | 1 | 6 | 59 |
GO:0030141 | secretory granule | 5.45e-02 | 1.00e+00 | 4.161 | 1 | 2 | 62 |
GO:0034329 | cell junction assembly | 5.96e-02 | 1.00e+00 | 4.028 | 1 | 1 | 68 |
GO:0003697 | single-stranded DNA binding | 5.96e-02 | 1.00e+00 | 4.028 | 1 | 5 | 68 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 6.47e-02 | 1.00e+00 | 3.906 | 1 | 6 | 74 |
GO:0044267 | cellular protein metabolic process | 6.62e-02 | 1.00e+00 | 2.227 | 2 | 29 | 474 |
GO:0030182 | neuron differentiation | 6.64e-02 | 1.00e+00 | 3.868 | 1 | 1 | 76 |
GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process | 6.72e-02 | 1.00e+00 | 3.849 | 1 | 7 | 77 |
GO:0002755 | MyD88-dependent toll-like receptor signaling pathway | 6.98e-02 | 1.00e+00 | 3.794 | 1 | 3 | 80 |
GO:0050821 | protein stabilization | 7.65e-02 | 1.00e+00 | 3.656 | 1 | 2 | 88 |
GO:0006928 | cellular component movement | 7.90e-02 | 1.00e+00 | 3.608 | 1 | 7 | 91 |
GO:0005200 | structural constituent of cytoskeleton | 7.90e-02 | 1.00e+00 | 3.608 | 1 | 8 | 91 |
GO:0006414 | translational elongation | 8.07e-02 | 1.00e+00 | 3.576 | 1 | 13 | 93 |
GO:0051082 | unfolded protein binding | 8.07e-02 | 1.00e+00 | 3.576 | 1 | 5 | 93 |
GO:0014069 | postsynaptic density | 9.07e-02 | 1.00e+00 | 3.401 | 1 | 3 | 105 |
GO:0005506 | iron ion binding | 9.07e-02 | 1.00e+00 | 3.401 | 1 | 4 | 105 |
GO:0015630 | microtubule cytoskeleton | 9.48e-02 | 1.00e+00 | 3.334 | 1 | 4 | 110 |
GO:0072562 | blood microparticle | 9.56e-02 | 1.00e+00 | 3.321 | 1 | 3 | 111 |
GO:0044237 | cellular metabolic process | 1.01e-01 | 1.00e+00 | 3.245 | 1 | 5 | 117 |
GO:0006325 | chromatin organization | 1.01e-01 | 1.00e+00 | 3.233 | 1 | 5 | 118 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 1.08e-01 | 1.00e+00 | 3.138 | 1 | 5 | 126 |
GO:0009615 | response to virus | 1.08e-01 | 1.00e+00 | 3.138 | 1 | 5 | 126 |
GO:0016055 | Wnt signaling pathway | 1.18e-01 | 1.00e+00 | 3.007 | 1 | 7 | 138 |
GO:0016887 | ATPase activity | 1.19e-01 | 1.00e+00 | 2.986 | 1 | 7 | 140 |
GO:0006457 | protein folding | 1.22e-01 | 1.00e+00 | 2.956 | 1 | 7 | 143 |
GO:0061024 | membrane organization | 1.23e-01 | 1.00e+00 | 2.936 | 1 | 7 | 145 |
GO:0010628 | positive regulation of gene expression | 1.24e-01 | 1.00e+00 | 2.926 | 1 | 5 | 146 |
GO:0005769 | early endosome | 1.29e-01 | 1.00e+00 | 2.868 | 1 | 2 | 152 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.39e-01 | 1.00e+00 | 2.749 | 1 | 7 | 165 |
GO:0030424 | axon | 1.40e-01 | 1.00e+00 | 2.741 | 1 | 4 | 166 |
GO:0005667 | transcription factor complex | 1.47e-01 | 1.00e+00 | 2.664 | 1 | 4 | 175 |
GO:0003714 | transcription corepressor activity | 1.49e-01 | 1.00e+00 | 2.640 | 1 | 8 | 178 |
GO:0003924 | GTPase activity | 1.64e-01 | 1.00e+00 | 2.494 | 1 | 12 | 197 |
GO:0006184 | GTP catabolic process | 1.77e-01 | 1.00e+00 | 2.374 | 1 | 12 | 214 |
GO:0006412 | translation | 1.89e-01 | 1.00e+00 | 2.270 | 1 | 20 | 230 |
GO:0005975 | carbohydrate metabolic process | 2.06e-01 | 1.00e+00 | 2.133 | 1 | 9 | 253 |
GO:0005615 | extracellular space | 2.12e-01 | 1.00e+00 | 1.213 | 2 | 17 | 957 |
GO:0043065 | positive regulation of apoptotic process | 2.16e-01 | 1.00e+00 | 2.050 | 1 | 10 | 268 |
GO:0005743 | mitochondrial inner membrane | 2.23e-01 | 1.00e+00 | 2.002 | 1 | 8 | 277 |
GO:0019899 | enzyme binding | 2.23e-01 | 1.00e+00 | 2.002 | 1 | 12 | 277 |
GO:0005739 | mitochondrion | 2.26e-01 | 1.00e+00 | 1.153 | 2 | 28 | 998 |
GO:0005856 | cytoskeleton | 2.33e-01 | 1.00e+00 | 1.931 | 1 | 12 | 291 |
GO:0006200 | ATP catabolic process | 2.34e-01 | 1.00e+00 | 1.926 | 1 | 15 | 292 |
GO:0044822 | poly(A) RNA binding | 2.46e-01 | 1.00e+00 | 1.071 | 2 | 49 | 1056 |
GO:0005525 | GTP binding | 2.46e-01 | 1.00e+00 | 1.840 | 1 | 12 | 310 |
GO:0007275 | multicellular organismal development | 2.50e-01 | 1.00e+00 | 1.812 | 1 | 5 | 316 |
GO:0007411 | axon guidance | 2.52e-01 | 1.00e+00 | 1.798 | 1 | 13 | 319 |
GO:0005813 | centrosome | 2.57e-01 | 1.00e+00 | 1.767 | 1 | 14 | 326 |
GO:0003682 | chromatin binding | 2.58e-01 | 1.00e+00 | 1.762 | 1 | 11 | 327 |
GO:0003723 | RNA binding | 2.68e-01 | 1.00e+00 | 1.698 | 1 | 20 | 342 |
GO:0005925 | focal adhesion | 2.84e-01 | 1.00e+00 | 1.600 | 1 | 19 | 366 |
GO:0009986 | cell surface | 3.08e-01 | 1.00e+00 | 1.465 | 1 | 11 | 402 |
GO:0045892 | negative regulation of transcription, DNA-templated | 3.15e-01 | 1.00e+00 | 1.426 | 1 | 15 | 413 |
GO:0006366 | transcription from RNA polymerase II promoter | 3.18e-01 | 1.00e+00 | 1.405 | 1 | 10 | 419 |
GO:0055114 | oxidation-reduction process | 3.19e-01 | 1.00e+00 | 1.401 | 1 | 12 | 420 |
GO:0005524 | ATP binding | 3.29e-01 | 1.00e+00 | 0.774 | 2 | 60 | 1298 |
GO:0007596 | blood coagulation | 3.41e-01 | 1.00e+00 | 1.286 | 1 | 18 | 455 |
GO:0042803 | protein homodimerization activity | 4.22e-01 | 1.00e+00 | 0.899 | 1 | 12 | 595 |
GO:0045087 | innate immune response | 4.22e-01 | 1.00e+00 | 0.896 | 1 | 24 | 596 |
GO:0005737 | cytoplasm | 4.53e-01 | 1.00e+00 | 0.236 | 4 | 110 | 3767 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 5.19e-01 | 1.00e+00 | 0.492 | 1 | 19 | 789 |
GO:0006355 | regulation of transcription, DNA-templated | 6.06e-01 | 1.00e+00 | 0.154 | 1 | 18 | 997 |
GO:0003677 | DNA binding | 6.83e-01 | 1.00e+00 | -0.135 | 1 | 28 | 1218 |
GO:0046872 | metal ion binding | 7.09e-01 | 1.00e+00 | -0.236 | 1 | 25 | 1307 |
GO:0006351 | transcription, DNA-templated | 7.47e-01 | 1.00e+00 | -0.382 | 1 | 31 | 1446 |
GO:0005886 | plasma membrane | 9.23e-01 | 1.00e+00 | -1.219 | 1 | 45 | 2582 |