reg-snw-1642

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.875	1.48e-07	1.08e-03	2.28e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-1642 subnetwork

Genes (5)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
TUBG1	7283	39	0.974	0.973	36	-	Yes	-
PSMB2	5690	23	0.877	0.956	52	-	Yes	-
PSMD11	5717	15	1.095	0.940	35	TF	Yes	-
HSPD1	3329	4	0.913	0.875	39	-	Yes	-
[ DDB1 ]	1642	1	0.515	0.875	43	TF	-	-

Interactions (5)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PSMB2	5690	PSMD11	5717	pd	<	reg.ITFP.txt: no annot
PSMD11	5717	TUBG1	7283	pd	>	reg.ITFP.txt: no annot
DDB1	1642	PSMB2	5690	pd	>	reg.ITFP.txt: no annot
DDB1	1642	HSPD1	3329	pd	>	reg.ITFP.txt: no annot
DDB1	1642	TUBG1	7283	pd	>	reg.ITFP.txt: no annot

Related GO terms (112)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0043066	negative regulation of apoptotic process	5.65e-06	5.52e-02	4.601	4	20	322
GO:0016032	viral process	1.76e-05	1.72e-01	4.190	4	32	428
GO:0006521	regulation of cellular amino acid metabolic process	1.71e-04	1.00e+00	6.574	2	16	41
GO:0000502	proteasome complex	2.25e-04	1.00e+00	6.377	2	17	47
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.75e-04	1.00e+00	6.231	2	17	52
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	2.86e-04	1.00e+00	6.204	2	17	53
GO:0000278	mitotic cell cycle	3.14e-04	1.00e+00	4.222	3	35	314
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.19e-04	1.00e+00	6.124	2	17	56
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	3.31e-04	1.00e+00	6.099	2	16	57
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.67e-04	1.00e+00	6.025	2	17	60
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	3.79e-04	1.00e+00	6.001	2	16	61
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	4.31e-04	1.00e+00	5.909	2	17	65
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	5.00e-04	1.00e+00	5.802	2	16	70
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	5.12e-04	1.00e+00	10.931	1	1	1
GO:0048291	isotype switching to IgG isotypes	5.12e-04	1.00e+00	10.931	1	1	1
GO:0002368	B cell cytokine production	5.12e-04	1.00e+00	10.931	1	1	1
GO:0000209	protein polyubiquitination	8.62e-04	1.00e+00	5.408	2	16	92
GO:0006458	'de novo' protein folding	1.02e-03	1.00e+00	9.931	1	1	2
GO:0034641	cellular nitrogen compound metabolic process	1.12e-03	1.00e+00	5.217	2	18	105
GO:0042981	regulation of apoptotic process	1.27e-03	1.00e+00	5.124	2	18	112
GO:1901990	regulation of mitotic cell cycle phase transition	1.54e-03	1.00e+00	9.347	1	1	3
GO:0003688	DNA replication origin binding	1.54e-03	1.00e+00	9.347	1	1	3
GO:0030135	coated vesicle	1.54e-03	1.00e+00	9.347	1	1	3
GO:0046696	lipopolysaccharide receptor complex	1.54e-03	1.00e+00	9.347	1	1	3
GO:0000082	G1/S transition of mitotic cell cycle	1.59e-03	1.00e+00	4.966	2	24	125
GO:0080008	Cul4-RING E3 ubiquitin ligase complex	2.05e-03	1.00e+00	8.931	1	1	4
GO:0000212	meiotic spindle organization	2.05e-03	1.00e+00	8.931	1	1	4
GO:0043248	proteasome assembly	2.05e-03	1.00e+00	8.931	1	1	4
GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex	2.56e-03	1.00e+00	8.610	1	1	5
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	2.56e-03	1.00e+00	8.610	1	2	5
GO:0005827	polar microtubule	2.56e-03	1.00e+00	8.610	1	1	5
GO:0000930	gamma-tubulin complex	2.56e-03	1.00e+00	8.610	1	1	5
GO:0016071	mRNA metabolic process	2.91e-03	1.00e+00	4.522	2	21	170
GO:0043032	positive regulation of macrophage activation	3.07e-03	1.00e+00	8.347	1	1	6
GO:0070914	UV-damage excision repair	3.07e-03	1.00e+00	8.347	1	1	6
GO:0070062	extracellular vesicular exosome	3.44e-03	1.00e+00	2.251	4	43	1641
GO:0016070	RNA metabolic process	3.55e-03	1.00e+00	4.377	2	21	188
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	3.58e-03	1.00e+00	8.124	1	2	7
GO:0035518	histone H2A monoubiquitination	3.58e-03	1.00e+00	8.124	1	1	7
GO:0031122	cytoplasmic microtubule organization	4.09e-03	1.00e+00	7.931	1	2	8
GO:0032727	positive regulation of interferon-alpha production	4.09e-03	1.00e+00	7.931	1	1	8
GO:0051604	protein maturation	4.09e-03	1.00e+00	7.931	1	1	8
GO:0001530	lipopolysaccharide binding	4.60e-03	1.00e+00	7.762	1	1	9
GO:0005829	cytosol	4.78e-03	1.00e+00	2.128	4	58	1787
GO:0042026	protein refolding	5.11e-03	1.00e+00	7.610	1	1	10
GO:0005838	proteasome regulatory particle	5.11e-03	1.00e+00	7.610	1	4	10
GO:0051131	chaperone-mediated protein complex assembly	5.11e-03	1.00e+00	7.610	1	1	10
GO:0007020	microtubule nucleation	5.62e-03	1.00e+00	7.472	1	1	11
GO:0048863	stem cell differentiation	6.13e-03	1.00e+00	7.347	1	1	12
GO:0005654	nucleoplasm	6.27e-03	1.00e+00	2.742	3	55	876
GO:0032733	positive regulation of interleukin-10 production	6.64e-03	1.00e+00	7.231	1	1	13
GO:0010243	response to organonitrogen compound	7.15e-03	1.00e+00	7.124	1	1	14
GO:0022624	proteasome accessory complex	7.15e-03	1.00e+00	7.124	1	7	14
GO:0050870	positive regulation of T cell activation	7.15e-03	1.00e+00	7.124	1	1	14
GO:0042113	B cell activation	8.17e-03	1.00e+00	6.931	1	1	16
GO:0005839	proteasome core complex	8.17e-03	1.00e+00	6.931	1	9	16
GO:0042100	B cell proliferation	8.68e-03	1.00e+00	6.844	1	1	17
GO:0004298	threonine-type endopeptidase activity	8.68e-03	1.00e+00	6.844	1	9	17
GO:0000718	nucleotide-excision repair, DNA damage removal	8.68e-03	1.00e+00	6.844	1	5	17
GO:0000794	condensed nuclear chromosome	9.18e-03	1.00e+00	6.762	1	3	18
GO:0032735	positive regulation of interleukin-12 production	1.02e-02	1.00e+00	6.610	1	1	20
GO:0005515	protein binding	1.34e-02	1.00e+00	1.244	5	76	4124
GO:0032755	positive regulation of interleukin-6 production	1.38e-02	1.00e+00	6.177	1	1	27
GO:0032729	positive regulation of interferon-gamma production	1.43e-02	1.00e+00	6.124	1	1	28
GO:0016020	membrane	1.55e-02	1.00e+00	2.279	3	38	1207
GO:0006915	apoptotic process	1.62e-02	1.00e+00	3.248	2	21	411
GO:0042110	T cell activation	1.68e-02	1.00e+00	5.887	1	1	33
GO:0014070	response to organic cyclic compound	1.73e-02	1.00e+00	5.844	1	1	34
GO:0006986	response to unfolded protein	1.78e-02	1.00e+00	5.802	1	1	35
GO:0000226	microtubule cytoskeleton organization	1.83e-02	1.00e+00	5.762	1	2	36
GO:0005905	coated pit	1.88e-02	1.00e+00	5.722	1	2	37
GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.88e-02	1.00e+00	5.722	1	1	37
GO:0003684	damaged DNA binding	2.08e-02	1.00e+00	5.574	1	9	41
GO:0030141	secretory granule	2.23e-02	1.00e+00	5.472	1	1	44
GO:0051087	chaperone binding	2.28e-02	1.00e+00	5.440	1	3	45
GO:0003725	double-stranded RNA binding	2.28e-02	1.00e+00	5.440	1	3	45
GO:0002039	p53 binding	2.28e-02	1.00e+00	5.440	1	2	45
GO:0010467	gene expression	2.68e-02	1.00e+00	2.868	2	31	535
GO:0006289	nucleotide-excision repair	2.69e-02	1.00e+00	5.204	1	9	53
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	2.84e-02	1.00e+00	5.124	1	3	56
GO:0003697	single-stranded DNA binding	2.89e-02	1.00e+00	5.099	1	6	57
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	3.09e-02	1.00e+00	5.001	1	1	61
GO:0050821	protein stabilization	3.23e-02	1.00e+00	4.931	1	1	64
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	3.38e-02	1.00e+00	4.865	1	2	67
GO:0005200	structural constituent of cytoskeleton	3.43e-02	1.00e+00	4.844	1	2	68
GO:0051082	unfolded protein binding	3.53e-02	1.00e+00	4.802	1	4	70
GO:0005615	extracellular space	3.88e-02	1.00e+00	2.585	2	8	651
GO:0016055	Wnt signaling pathway	4.38e-02	1.00e+00	4.489	1	1	87
GO:0006511	ubiquitin-dependent protein catabolic process	4.62e-02	1.00e+00	4.408	1	2	92
GO:0000086	G2/M transition of mitotic cell cycle	4.87e-02	1.00e+00	4.332	1	5	97
GO:0016887	ATPase activity	5.02e-02	1.00e+00	4.288	1	6	100
GO:0005769	early endosome	5.46e-02	1.00e+00	4.163	1	1	109
GO:0003924	GTPase activity	5.95e-02	1.00e+00	4.037	1	3	119
GO:0044281	small molecule metabolic process	6.26e-02	1.00e+00	2.210	2	32	844
GO:0006184	GTP catabolic process	6.48e-02	1.00e+00	3.909	1	3	130
GO:0005759	mitochondrial matrix	6.92e-02	1.00e+00	3.813	1	5	139
GO:0005743	mitochondrial inner membrane	9.69e-02	1.00e+00	3.309	1	3	197
GO:0005525	GTP binding	9.69e-02	1.00e+00	3.309	1	5	197
GO:0043065	positive regulation of apoptotic process	9.93e-02	1.00e+00	3.273	1	3	202
GO:0006281	DNA repair	9.97e-02	1.00e+00	3.266	1	19	203
GO:0043234	protein complex	1.03e-01	1.00e+00	3.217	1	8	210
GO:0005813	centrosome	1.06e-01	1.00e+00	3.170	1	8	217
GO:0006200	ATP catabolic process	1.07e-01	1.00e+00	3.157	1	8	219
GO:0005737	cytoplasm	1.25e-01	1.00e+00	1.154	3	50	2633
GO:0009986	cell surface	1.40e-01	1.00e+00	2.747	1	2	291
GO:0005634	nucleus	2.08e-01	1.00e+00	0.852	3	67	3246
GO:0005739	mitochondrion	2.95e-01	1.00e+00	1.567	1	11	659
GO:0044822	poly(A) RNA binding	3.47e-01	1.00e+00	1.289	1	25	799
GO:0005524	ATP binding	3.81e-01	1.00e+00	1.131	1	23	892
GO:0003677	DNA binding	4.00e-01	1.00e+00	1.044	1	18	947
GO:0005730	nucleolus	4.86e-01	1.00e+00	0.682	1	41	1217
GO:0005886	plasma membrane	6.35e-01	1.00e+00	0.131	1	11	1784

Wolf-ratios-Mammosphere-Adherent

reg-snw-1642

Statistics

Genes (5)

Interactions (5)

Related GO terms (112)