meta-int-snw-373156

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-11277 wolf-screen-ratio-mammosphere-adherent 0.882 1.09e-07 9.11e-04 1.96e-03 10 9
int-snw-373156 wolf-screen-ratio-mammosphere-adherent 0.921 5.46e-15 3.31e-03 4.93e-02 13 12
reg-snw-4522 wolf-screen-ratio-mammosphere-adherent 0.815 1.50e-06 3.75e-03 6.95e-03 14 12
reg-snw-158 wolf-screen-ratio-mammosphere-adherent 0.934 1.18e-08 2.65e-04 6.55e-04 9 8
reg-snw-56655 wolf-screen-ratio-mammosphere-adherent 0.828 9.29e-07 2.91e-03 5.53e-03 8 7
reg-snw-317781 wolf-screen-ratio-mammosphere-adherent 0.823 1.13e-06 3.23e-03 6.07e-03 9 9
reg-snw-1434 wolf-screen-ratio-mammosphere-adherent 0.865 2.23e-07 1.35e-03 2.78e-03 9 7
reg-snw-10213 wolf-screen-ratio-mammosphere-adherent 0.815 1.49e-06 3.74e-03 6.93e-03 7 6
reg-snw-5686 wolf-screen-ratio-mammosphere-adherent 0.878 1.30e-07 1.01e-03 2.15e-03 5 4
wolf-screen-ratio-mammosphere-adherent-meta-int-snw-373156 subnetwork

Genes (40)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
PSMB1 5689 610.6880.901113Yes-
PSMA3 5684 900.5330.815238Yes-
PSMA2 5683 1121.0931.106108Yes-
POLR2F 5435 620.8910.95626Yes-
CSE1L 1434 410.3040.86554Yes-
VARS 7407 860.5491.002204Yes-
DDX51 317781 530.0590.823210Yes-
RPA2 6118 961.2501.15176Yes-
CAD 790 910.8070.973400--
EIF6 3692 670.7000.876316Yes-
GSTK1 373156 9-0.1850.92197--
CCNA2 890 540.5500.973246Yes-
PSMD1 5707 860.8360.830118Yes-
EFTUD2 9343 930.8830.956108Yes-
PSMD14 10213 440.2990.81532--
TUBG1 7283 980.9740.97391Yes-
PSMD11 5717 1241.0951.106218Yes-
RAN 5901 890.6320.899258Yes-
PRMT3 10196 490.4310.81526--
PSMA5 5686 350.3780.87833--
DCTN1 1639 100.4230.93386Yes-
MTHFD1 4522 490.1940.81526Yes-
RBX1 9978 1151.1850.934148Yes-
HNRNPC 3183 1081.8120.973181Yes-
PSMB7 5695 1180.9820.93490Yes-
ADSL 158 150.1070.93426--
PSMA1 5682 1000.9960.878152Yes-
TREX1 11277 51-0.0510.88291Yes-
POLE4 56655 630.1770.82856--
PSMB3 5691 640.6680.90119Yes-
RPSA 3921 1201.3271.151152Yes-
RPA1 6117 510.4250.86574--
CDC16 8881 530.9501.02080Yes-
RUVBL1 8607 950.7200.973469Yes-
PSMD3 5709 1000.9861.106201Yes-
LRPPRC 10128 11-0.5581.09561-Yes
PSMB2 5690 1160.8770.956169Yes-
ACTB 60 1341.1531.151610Yes-
RUVBL2 10856 950.6930.956532Yes-
PSMD6 9861 790.8480.878143Yes-

Interactions (194)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMA3 5684 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, Krogan_Core
PSMD11 5717 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, INTEROLOG
HNRNPC 3183 PSMA3 5684 pp -- int.I2D: BioGrid
PSMA1 5682 PSMB2 5690 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
PSMA5 5686 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMD11 5717 RUVBL1 8607 pp -- int.I2D: YeastLow
PSMA1 5682 PSMB1 5689 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, BIND_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, IntAct, IntAct_Mouse, IntAct_Yeast, Yu_GoldStd
CSE1L 1434 PSMD14 10213 pd < reg.ITFP.txt: no annot
CSE1L 1434 RAN 5901 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid_Yeast, HPRD, IntAct_Yeast, MIPS, IntAct, INTEROLOG;
int.HPRD: in vitro
CAD 790 CDC16 8881 pp -- int.I2D: IntAct_Yeast
EFTUD2 9343 RUVBL2 10856 pd < reg.ITFP.txt: no annot
EFTUD2 9343 RUVBL2 10856 pp -- int.I2D: BioGrid
CAD 790 RPA1 6117 pd < reg.ITFP.txt: no annot
MTHFD1 4522 PSMA3 5684 pp -- int.I2D: BioGrid
PSMB2 5690 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMD1 5707 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, Krogan_Core
PSMA5 5686 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RUVBL1 8607 pp -- int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
CCNA2 890 RUVBL1 8607 pd <> reg.ITFP.txt: no annot
PSMB3 5691 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPA1 6117 RUVBL1 8607 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
RPA1 6117 VARS 7407 pp -- int.I2D: YeastLow
CAD 790 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow
PSMB1 5689 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RAN 5901 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastHigh, IntAct, Yu_GoldStd;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
PSMB2 5690 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMB3 5691 PSMD3 5709 pp -- int.I2D: YeastLow
PSMA2 5683 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
CAD 790 RUVBL1 8607 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL1 8607 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA2 5683 PSMA5 5686 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, MINT_Yeast, YeastHigh, BIND_Yeast, IntAct_Fly, Krogan_Core
RPA1 6117 TREX1 11277 pp -- int.I2D: BCI;
int.HPRD: in vitro
PSMA3 5684 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMD14 10213 pp -- int.I2D: BioGrid, BioGrid_Yeast
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
CCNA2 890 CSE1L 1434 pd > reg.ITFP.txt: no annot
RPA1 6117 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMB1 5689 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, MINT, YeastHigh, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast;
int.Mint: MI:0915(physical association)
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
TREX1 11277 DDX51 317781 pd <> reg.ITFP.txt: no annot
ADSL 158 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 PSMB3 5691 pp -- int.Intact: MI:0914(association);
int.I2D: IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Yeast, YeastHigh, BioGrid_Yeast
PSMA1 5682 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastMedium
RPSA 3921 VARS 7407 pp -- int.I2D: IntAct_Yeast
PSMD3 5709 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
PSMD1 5707 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMA1 5682 PSMA2 5683 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
RPSA 3921 RAN 5901 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
PSMD6 9861 RUVBL2 10856 pp -- int.I2D: YeastLow
TUBG1 7283 VARS 7407 pd < reg.ITFP.txt: no annot
CSE1L 1434 RPA1 6117 pd < reg.ITFP.txt: no annot
ADSL 158 CAD 790 pp -- int.I2D: YeastLow
ACTB 60 PSMA3 5684 pp -- int.I2D: BioGrid, BioGrid_Yeast
RUVBL1 8607 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
RUVBL1 8607 RUVBL2 10856 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid, BioGrid_Mouse, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct, IntAct_Fly, IntAct_Worm, IntAct_Yeast, INTEROLOG, MINT_Worm, MINT_Yeast, BCI, BioGrid_Fly, BIND_Fly, BIND_Worm, FlyHigh, INNATEDB, Krogan_Core, MIPS, YeastHigh, Yu_GoldStd;
int.Ravasi: -;
int.HPRD: in vitro, in vivo, yeast 2-hybrid;
int.DIP: MI:0915(physical association)
PSMA1 5682 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, BioGrid, YeastMedium
ADSL 158 PSMD11 5717 pp -- int.I2D: Krogan_NonCore
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
EFTUD2 9343 GSTK1 373156 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, BioGrid
MTHFD1 4522 PRMT3 10196 pd < reg.ITFP.txt: no annot
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
ACTB 60 CAD 790 pp -- int.I2D: IntAct_Yeast
PSMD1 5707 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMD1 5707 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast
ADSL 158 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMA1 5682 RPA1 6117 pd < reg.ITFP.txt: no annot
PSMB7 5695 RBX1 9978 pd < reg.ITFP.txt: no annot
PSMA3 5684 RUVBL2 10856 pp -- int.I2D: YeastLow
CAD 790 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
HNRNPC 3183 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMD3 5709 RUVBL2 10856 pp -- int.I2D: YeastLow
VARS 7407 POLE4 56655 pd <> reg.ITFP.txt: no annot
PSMA2 5683 PSMB3 5691 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd
PSMD3 5709 TUBG1 7283 pd > reg.ITFP.txt: no annot
PSMD11 5717 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, IntAct, INTEROLOG
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
CAD 790 DDX51 317781 pp -- int.I2D: IntAct_Yeast
VARS 7407 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
HNRNPC 3183 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMA5 5686 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastHigh, Yu_GoldStd, Krogan_Core, MINT_Yeast
CSE1L 1434 RPSA 3921 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA2 5683 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMB7 5695 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastLow, IntAct, Krogan_Core, MINT_Yeast, Yu_GoldStd;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
VARS 7407 RUVBL1 8607 pd <> reg.ITFP.txt: no annot
PSMA3 5684 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow
PSMD1 5707 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, IntAct, Krogan_Core
PSMA3 5684 PSMD1 5707 pp -- int.I2D: BioGrid, BioGrid_Yeast
PSMA5 5686 PSMB3 5691 pp -- int.I2D: BioGrid_Yeast, YeastHigh
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 EFTUD2 9343 pp -- int.I2D: BioGrid
PSMB2 5690 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMB7 5695 DDX51 317781 pd < reg.ITFP.txt: no annot
PSMB7 5695 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, MINT_Yeast, YeastLow, Krogan_Core
MTHFD1 4522 RUVBL1 8607 pd < reg.ITFP.txt: no annot
MTHFD1 4522 VARS 7407 pd < reg.ITFP.txt: no annot
MTHFD1 4522 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
PSMD3 5709 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, IntAct, IntAct_Yeast, MINT_Worm, MINT_Yeast, YeastHigh, BioGrid, BIND_Yeast, IntAct_Worm, INTEROLOG, Krogan_Core, MIPS
PSMA5 5686 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
TUBG1 7283 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 RUVBL1 8607 pp -- int.I2D: BioGrid
PSMB7 5695 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RAN 5901 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, NON_CORE
RAN 5901 VARS 7407 pd < reg.ITFP.txt: no annot
TUBG1 7283 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMD6 9861 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh
POLR2F 5435 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 RAN 5901 pp -- int.I2D: IntAct_Yeast
PSMB3 5691 PSMB7 5695 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, YeastHigh, HPRD, Krogan_Core, MINT_Yeast, MIPS;
int.HPRD: yeast 2-hybrid
ACTB 60 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
MTHFD1 4522 RPA1 6117 pd < reg.ITFP.txt: no annot
VARS 7407 DDX51 317781 pd <> reg.ITFP.txt: no annot
RUVBL1 8607 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMD3 5709 VARS 7407 pd <> reg.ITFP.txt: no annot
PSMB7 5695 PSMD1 5707 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct
PSMA1 5682 PSMA3 5684 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, CE_DATA, HPRD, IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Worm, IntAct_Yeast, MINT_Worm, BioGrid, BioGrid_Fly, BIND_Fly, BIND_Yeast, FlyHigh, Krogan_Core, MINT_Fly, MINT_Yeast, YeastHigh, Yu_GoldStd;
int.HPRD: in vitro
PSMB7 5695 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMA2 5683 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMD11 5717 TUBG1 7283 pd > reg.ITFP.txt: no annot
PSMA2 5683 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPSA 3921 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA1 5682 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
ADSL 158 RBX1 9978 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, INTEROLOG, MINT, Yu_GoldStd, BCI, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
ACTB 60 RPA2 6118 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMB1 5689 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
MTHFD1 4522 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMA5 5686 POLE4 56655 pd < reg.ITFP.txt: no annot
CAD 790 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 DDX51 317781 pd < reg.ITFP.txt: no annot
DCTN1 1639 GSTK1 373156 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, BioGrid
PSMB7 5695 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct
PSMD11 5717 EFTUD2 9343 pd > reg.ITFP.txt: no annot
RUVBL1 8607 PSMD6 9861 pp -- int.I2D: YeastLow
ACTB 60 CDC16 8881 pp -- int.I2D: YeastLow
PSMD11 5717 RUVBL2 10856 pp -- int.I2D: YeastLow
RPA1 6117 RPA2 6118 pp -- int.Intact: MI:0407(direct interaction), MI:0915(physical association);
int.I2D: HPRD, BCI, BioGrid, BIND, IntAct;
int.Transfac: -;
int.HPRD: in vitro, in vivo
PSMB3 5691 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMB1 5689 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, IntAct_Yeast, YeastHigh
VARS 7407 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
PSMA5 5686 PSMB1 5689 pp -- int.I2D: BioGrid_Yeast, BIND_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd
PSMB1 5689 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMD1 5707 RUVBL2 10856 pp -- int.I2D: IntAct_Yeast
PSMA3 5684 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMB2 5690 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMA3 5684 PSMA5 5686 pp -- int.I2D: BioGrid_Yeast, BIND_Yeast, IntAct_Mouse, IntAct_Yeast, MINT_Yeast, YeastHigh, Krogan_Core, Tarassov_PCA
PSMB1 5689 TREX1 11277 pd < reg.ITFP.txt: no annot
ADSL 158 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
LRPPRC 10128 GSTK1 373156 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, BioGrid
ACTB 60 CSE1L 1434 pp -- int.I2D: IntAct_Yeast
PSMA3 5684 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB2 5690 PSMD11 5717 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB2 5690 VARS 7407 pd < reg.ITFP.txt: no annot
EIF6 3692 PSMB1 5689 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMA2 5683 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow, BioGrid
PSMB3 5691 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastLow
PSMA2 5683 PSMB1 5689 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, BCI, BioGrid, IntAct, YeastHigh
RPSA 3921 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RPA1 6117 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
ACTB 60 ADSL 158 pp -- int.I2D: BioGrid_Yeast
PSMD14 10213 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB3 5691 PSMD11 5717 pp -- int.I2D: YeastLow
PSMD3 5709 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, INTEROLOG, MINT_Yeast, Krogan_Core, YeastHigh
ACTB 60 LRPPRC 10128 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMB7 5695 RPA1 6117 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, MINT_Yeast, IntAct_Yeast, Krogan_Core, YeastHigh
CCNA2 890 RPA1 6117 pp -- int.I2D: BioGrid
EIF6 3692 DDX51 317781 pd < reg.ITFP.txt: no annot
EIF6 3692 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RAN 5901 TREX1 11277 pd < reg.ITFP.txt: no annot
RUVBL2 10856 TREX1 11277 pd <> reg.ITFP.txt: no annot
ACTB 60 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid
CAD 790 RPSA 3921 pp -- int.I2D: IntAct_Yeast
PSMA2 5683 PSMA3 5684 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BIND_Yeast, HPRD;
int.HPRD: yeast 2-hybrid
PSMA3 5684 PSMB3 5691 pp -- int.I2D: BioGrid_Yeast, IntAct_Fly, IntAct_Yeast, YeastHigh
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
POLR2F 5435 VARS 7407 pd < reg.ITFP.txt: no annot
ACTB 60 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB2 5690 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core
EIF6 3692 RUVBL1 8607 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct

Related GO terms (428)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.21e-241.97e-206.458142465
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle3.80e-246.20e-206.351142470
GO:0006521regulation of cellular amino acid metabolic process4.33e-247.06e-206.729132150
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle8.91e-241.45e-196.270142474
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process2.41e-233.94e-196.176142579
GO:0000502proteasome complex3.80e-236.21e-196.515132258
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1.96e-223.19e-186.351132265
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent1.02e-211.66e-176.183132373
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I2.15e-213.51e-176.106132377
GO:0005654nucleoplasm2.19e-213.58e-173.27626831095
GO:0000082G1/S transition of mitotic cell cycle4.56e-217.43e-175.3511533150
GO:0000278mitotic cell cycle1.22e-201.99e-164.2841952398
GO:0002474antigen processing and presentation of peptide antigen via MHC class I3.43e-205.60e-165.818132394
GO:0000209protein polyubiquitination6.06e-199.89e-155.5151321116
GO:0042981regulation of apoptotic process2.09e-173.41e-135.1351326151
GO:0005839proteasome core complex2.65e-174.33e-137.50381118
GO:0004298threonine-type endopeptidase activity7.61e-171.24e-127.35181120
GO:0016071mRNA metabolic process8.89e-171.45e-124.6791434223
GO:0034641cellular nitrogen compound metabolic process1.72e-162.80e-124.9051325177
GO:0010467gene expression1.99e-163.25e-123.5351958669
GO:0016070RNA metabolic process3.74e-166.10e-124.5321434247
GO:0016032viral process2.33e-153.81e-113.6831755540
GO:0005829cytosol2.13e-143.48e-102.157281252562
GO:0043066negative regulation of apoptotic process1.69e-112.76e-073.6151330433
GO:0006915apoptotic process3.53e-115.76e-073.3231434571
GO:0070062extracellular vesicular exosome1.47e-102.40e-061.96124982516
GO:0022624proteasome accessory complex4.13e-106.74e-066.9075917
GO:0019773proteasome core complex, alpha-subunit complex2.15e-093.51e-057.673458
GO:0044281small molecule metabolic process2.70e-094.41e-052.42117571295
GO:0016020membrane3.47e-085.66e-042.07318801746
GO:0005634nucleus7.86e-071.28e-021.190271314828
GO:0005730nucleolus8.65e-071.41e-021.95516701684
GO:0005838proteasome regulatory particle2.95e-064.82e-026.6733712
GO:0006281DNA repair3.16e-065.16e-023.435722264
GO:0035267NuA4 histone acetyltransferase complex4.87e-067.95e-026.4503414
GO:0006298mismatch repair1.51e-052.47e-015.9363620
GO:0006310DNA recombination2.12e-053.46e-014.6064467
GO:0003697single-stranded DNA binding2.38e-053.89e-014.5644969
GO:0005515protein binding3.09e-055.05e-010.899281726127
GO:0000730DNA recombinase assembly5.83e-059.51e-017.351235
GO:0000812Swr1 complex1.62e-041.00e+006.673238
GO:0006164purine nucleotide biosynthetic process1.62e-041.00e+006.673228
GO:0030529ribonucleoprotein complex1.70e-041.00e+003.84048114
GO:0006283transcription-coupled nucleotide-excision repair1.92e-041.00e+004.7343846
GO:0007067mitotic nuclear division2.39e-041.00e+003.143513231
GO:0003684damaged DNA binding2.62e-041.00e+004.58531151
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding3.10e-041.00e+004.5033554
GO:0000724double-strand break repair via homologous recombination3.64e-041.00e+004.4253657
GO:0043968histone H2A acetylation3.81e-041.00e+006.0882312
GO:0005662DNA replication factor A complex4.49e-041.00e+005.9722313
GO:0030234enzyme regulator activity4.49e-041.00e+005.9722313
GO:0031011Ino80 complex5.23e-041.00e+005.8652314
GO:0006289nucleotide-excision repair6.39e-041.00e+004.14931269
GO:0042176regulation of protein catabolic process6.88e-041.00e+005.6732316
GO:0006259DNA metabolic process9.75e-041.00e+005.4252319
GO:0003678DNA helicase activity9.75e-041.00e+005.4252319
GO:0000718nucleotide-excision repair, DNA damage removal1.19e-031.00e+005.2802521
GO:0006297nucleotide-excision repair, DNA gap filling1.31e-031.00e+005.2132522
GO:0032201telomere maintenance via semi-conservative replication1.31e-031.00e+005.2132722
GO:0043044ATP-dependent chromatin remodeling1.43e-031.00e+005.1492423
GO:0016363nuclear matrix1.47e-031.00e+003.73431192
GO:0000794condensed nuclear chromosome1.56e-031.00e+005.0882224
GO:0006611protein export from nucleus1.70e-031.00e+005.0292425
GO:0000722telomere maintenance via recombination1.83e-031.00e+004.9722726
GO:0071339MLL1 complex1.98e-031.00e+004.9182327
GO:0043022ribosome binding2.13e-031.00e+004.8652328
GO:0043967histone H4 acetylation2.13e-031.00e+004.8652328
GO:0031492nucleosomal DNA binding2.13e-031.00e+004.8652428
GO:0004088carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity2.45e-031.00e+008.673111
GO:0070335aspartate binding2.45e-031.00e+008.673111
GO:0008262importin-alpha export receptor activity2.45e-031.00e+008.673111
GO:0008541proteasome regulatory particle, lid subcomplex2.45e-031.00e+008.673111
GO:0070626(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity2.45e-031.00e+008.673111
GO:0004018N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity2.45e-031.00e+008.673111
GO:0032558adenyl deoxyribonucleotide binding2.45e-031.00e+008.673111
GO:0010970microtubule-based transport2.45e-031.00e+008.673111
GO:0004151dihydroorotase activity2.45e-031.00e+008.673111
GO:0000054ribosomal subunit export from nucleus2.45e-031.00e+008.673111
GO:0004070aspartate carbamoyltransferase activity2.45e-031.00e+008.673111
GO:0004486methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity2.45e-031.00e+008.673111
GO:0006271DNA strand elongation involved in DNA replication2.60e-031.00e+004.7182931
GO:0006325chromatin organization3.37e-031.00e+003.31534123
GO:0005737cytoplasm3.42e-031.00e+000.88518983976
GO:0006260DNA replication3.52e-031.00e+003.292312125
GO:0006284base-excision repair4.10e-031.00e+004.3872739
GO:0000086G2/M transition of mitotic cell cycle4.56e-031.00e+003.15937137
GO:0032508DNA duplex unwinding4.74e-031.00e+004.2802442
GO:0004832valine-tRNA ligase activity4.90e-031.00e+007.673112
GO:0006407rRNA export from nucleus4.90e-031.00e+007.673112
GO:0006438valyl-tRNA aminoacylation4.90e-031.00e+007.673112
GO:0000105histidine biosynthetic process4.90e-031.00e+007.673112
GO:00082963'-5'-exodeoxyribonuclease activity4.90e-031.00e+007.673112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)4.90e-031.00e+007.673112
GO:0000961negative regulation of mitochondrial RNA catabolic process4.90e-031.00e+007.673112
GO:0005055laminin receptor activity4.90e-031.00e+007.673112
GO:0070409carbamoyl phosphate biosynthetic process4.90e-031.00e+007.673112
GO:0016887ATPase activity5.23e-031.00e+003.08837144
GO:0031100organ regeneration6.66e-031.00e+004.0292450
GO:0040008regulation of growth6.92e-031.00e+004.0002351
GO:0071899negative regulation of estrogen receptor binding7.33e-031.00e+007.088113
GO:0071733transcriptional activation by promoter-enhancer looping7.33e-031.00e+007.088113
GO:0000056ribosomal small subunit export from nucleus7.33e-031.00e+007.088113
GO:0044208'de novo' AMP biosynthetic process7.33e-031.00e+007.088113
GO:0044205'de novo' UMP biosynthetic process7.33e-031.00e+007.088113
GO:0070129regulation of mitochondrial translation7.33e-031.00e+007.088113
GO:0006207'de novo' pyrimidine nucleobase biosynthetic process7.33e-031.00e+007.088113
GO:0000398mRNA splicing, via spliceosome7.62e-031.00e+002.891312165
GO:0000723telomere maintenance9.18e-031.00e+003.7902859
GO:0005813centrosome9.28e-031.00e+002.267412339
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)9.77e-031.00e+006.673114
GO:0000212meiotic spindle organization9.77e-031.00e+006.673114
GO:003068690S preribosome9.77e-031.00e+006.673114
GO:0006167AMP biosynthetic process9.77e-031.00e+006.673114
GO:0019788NEDD8 ligase activity9.77e-031.00e+006.673114
GO:0016274protein-arginine N-methyltransferase activity9.77e-031.00e+006.673114
GO:0004488methylenetetrahydrofolate dehydrogenase (NADP+) activity9.77e-031.00e+006.673114
GO:0004329formate-tetrahydrofolate ligase activity9.77e-031.00e+006.673114
GO:0043141ATP-dependent 5'-3' DNA helicase activity9.77e-031.00e+006.673114
GO:0034969histone arginine methylation9.77e-031.00e+006.673114
GO:0006543glutamine catabolic process9.77e-031.00e+006.673114
GO:0009396folic acid-containing compound biosynthetic process9.77e-031.00e+006.673114
GO:0004477methenyltetrahydrofolate cyclohydrolase activity9.77e-031.00e+006.673114
GO:0031467Cul7-RING ubiquitin ligase complex9.77e-031.00e+006.673114
GO:0000055ribosomal large subunit export from nucleus9.77e-031.00e+006.673114
GO:0008853exodeoxyribonuclease III activity9.77e-031.00e+006.673114
GO:0032481positive regulation of type I interferon production9.78e-031.00e+003.7422661
GO:0006302double-strand break repair1.01e-021.00e+003.7182862
GO:0051414response to cortisol1.22e-021.00e+006.351115
GO:0031465Cul4B-RING E3 ubiquitin ligase complex1.22e-021.00e+006.351125
GO:0042256mature ribosome assembly1.22e-021.00e+006.351115
GO:0001940male pronucleus1.22e-021.00e+006.351115
GO:0009086methionine biosynthetic process1.22e-021.00e+006.351115
GO:0032407MutSalpha complex binding1.22e-021.00e+006.351115
GO:2000001regulation of DNA damage checkpoint1.22e-021.00e+006.351115
GO:0008622epsilon DNA polymerase complex1.22e-021.00e+006.351115
GO:0031461cullin-RING ubiquitin ligase complex1.22e-021.00e+006.351115
GO:0071169establishment of protein localization to chromatin1.22e-021.00e+006.351115
GO:0043248proteasome assembly1.22e-021.00e+006.351115
GO:0030891VCB complex1.22e-021.00e+006.351125
GO:0005827polar microtubule1.22e-021.00e+006.351115
GO:0005638lamin filament1.22e-021.00e+006.351115
GO:0061133endopeptidase activator activity1.22e-021.00e+006.351115
GO:0003924GTPase activity1.34e-021.00e+002.59239203
GO:0055086nucleobase-containing small molecule metabolic process1.38e-021.00e+003.4832573
GO:0006189'de novo' IMP biosynthetic process1.46e-021.00e+006.088116
GO:0043023ribosomal large subunit binding1.46e-021.00e+006.088126
GO:0031466Cul5-RING ubiquitin ligase complex1.46e-021.00e+006.088116
GO:0030957Tat protein binding1.46e-021.00e+006.088146
GO:0046134pyrimidine nucleoside biosynthetic process1.46e-021.00e+006.088116
GO:0032405MutLalpha complex binding1.46e-021.00e+006.088126
GO:0008469histone-arginine N-methyltransferase activity1.46e-021.00e+006.088116
GO:0071013catalytic step 2 spliceosome1.60e-021.00e+003.3692779
GO:0006184GTP catabolic process1.65e-021.00e+002.47639220
GO:0010950positive regulation of endopeptidase activity1.70e-021.00e+005.865117
GO:0000028ribosomal small subunit assembly1.70e-021.00e+005.865117
GO:0002161aminoacyl-tRNA editing activity1.70e-021.00e+005.865127
GO:0035242protein-arginine omega-N asymmetric methyltransferase activity1.70e-021.00e+005.865117
GO:0001939female pronucleus1.70e-021.00e+005.865117
GO:0031462Cul2-RING ubiquitin ligase complex1.70e-021.00e+005.865127
GO:0035999tetrahydrofolate interconversion1.70e-021.00e+005.865117
GO:0072341modified amino acid binding1.70e-021.00e+005.865117
GO:0000930gamma-tubulin complex1.70e-021.00e+005.865117
GO:0019919peptidyl-arginine methylation, to asymmetrical-dimethyl arginine1.70e-021.00e+005.865117
GO:0005681spliceosomal complex1.76e-021.00e+003.2972383
GO:0008380RNA splicing1.90e-021.00e+002.399313232
GO:0031464Cul4A-RING E3 ubiquitin ligase complex1.94e-021.00e+005.673128
GO:0001055RNA polymerase II activity1.94e-021.00e+005.673138
GO:0070688MLL5-L complex1.94e-021.00e+005.673118
GO:0005869dynactin complex1.94e-021.00e+005.673118
GO:0045116protein neddylation1.94e-021.00e+005.673128
GO:0000800lateral element1.94e-021.00e+005.673118
GO:0016605PML body2.13e-021.00e+003.1492592
GO:0014075response to amine2.18e-021.00e+005.503119
GO:0006228UTP biosynthetic process2.18e-021.00e+005.503119
GO:0010389regulation of G2/M transition of mitotic cell cycle2.18e-021.00e+005.503119
GO:0047497mitochondrion transport along microtubule2.18e-021.00e+005.503129
GO:0031000response to caffeine2.18e-021.00e+005.503129
GO:0005200structural constituent of cytoskeleton2.18e-021.00e+003.1332793
GO:0070628proteasome binding2.42e-021.00e+005.3511110
GO:0046655folic acid metabolic process2.42e-021.00e+005.3511110
GO:0006450regulation of translational fidelity2.42e-021.00e+005.3511210
GO:0045502dynein binding2.66e-021.00e+005.2131211
GO:0010569regulation of double-strand break repair via homologous recombination2.66e-021.00e+005.2131111
GO:0031571mitotic G1 DNA damage checkpoint2.66e-021.00e+005.2131311
GO:0001054RNA polymerase I activity2.66e-021.00e+005.2131311
GO:0045120pronucleus2.66e-021.00e+005.2131111
GO:0033762response to glucagon2.66e-021.00e+005.2131111
GO:0035458cellular response to interferon-beta2.66e-021.00e+005.2131211
GO:0009168purine ribonucleoside monophosphate biosynthetic process2.90e-021.00e+005.0881112
GO:0061136regulation of proteasomal protein catabolic process2.90e-021.00e+005.0881112
GO:00709353'-UTR-mediated mRNA stabilization2.90e-021.00e+005.0881212
GO:0005736DNA-directed RNA polymerase I complex2.90e-021.00e+005.0881312
GO:0042273ribosomal large subunit biogenesis3.14e-021.00e+004.9721413
GO:0030286dynein complex3.14e-021.00e+004.9721113
GO:0032479regulation of type I interferon production3.14e-021.00e+004.9721213
GO:0000738DNA catabolic process, exonucleolytic3.14e-021.00e+004.9721213
GO:0008266poly(U) RNA binding3.14e-021.00e+004.9721113
GO:0019058viral life cycle3.23e-021.00e+002.827210115
GO:0007020microtubule nucleation3.38e-021.00e+004.8651114
GO:0007095mitotic G2 DNA damage checkpoint3.38e-021.00e+004.8651114
GO:0004602glutathione peroxidase activity3.38e-021.00e+004.8651114
GO:0035066positive regulation of histone acetylation3.62e-021.00e+004.7661115
GO:0030904retromer complex3.62e-021.00e+004.7661215
GO:0005671Ada2/Gcn5/Ada3 transcription activator complex3.62e-021.00e+004.7661115
GO:0006261DNA-dependent DNA replication3.62e-021.00e+004.7661215
GO:0043234protein complex3.68e-021.00e+002.029317300
GO:0006200ATP catabolic process3.78e-021.00e+002.014314303
GO:0005665DNA-directed RNA polymerase II, core complex3.85e-021.00e+004.6731416
GO:0050998nitric-oxide synthase binding3.85e-021.00e+004.6731116
GO:0001673male germ cell nucleus3.85e-021.00e+004.6731116
GO:0001056RNA polymerase III activity3.85e-021.00e+004.6731316
GO:00084083'-5' exonuclease activity3.85e-021.00e+004.6731216
GO:0006511ubiquitin-dependent protein catabolic process3.87e-021.00e+002.68425127
GO:0010243response to organonitrogen compound4.09e-021.00e+004.5851217
GO:0005666DNA-directed RNA polymerase III complex4.09e-021.00e+004.5851317
GO:0006413translational initiation4.09e-021.00e+002.639212131
GO:0075733intracellular transport of virus4.09e-021.00e+004.5851217
GO:0007126meiotic nuclear division4.09e-021.00e+004.5851117
GO:0000790nuclear chromatin4.20e-021.00e+002.61727133
GO:0070536protein K63-linked deubiquitination4.32e-021.00e+004.5031118
GO:0006386termination of RNA polymerase III transcription4.32e-021.00e+004.5031318
GO:0071392cellular response to estradiol stimulus4.32e-021.00e+004.5031118
GO:0006541glutamine metabolic process4.32e-021.00e+004.5031118
GO:0031122cytoplasmic microtubule organization4.32e-021.00e+004.5031218
GO:0035861site of double-strand break4.32e-021.00e+004.5031118
GO:0006385transcription elongation from RNA polymerase III promoter4.32e-021.00e+004.5031318
GO:0006303double-strand break repair via nonhomologous end joining4.32e-021.00e+004.5031318
GO:0005524ATP binding4.43e-021.00e+001.0777461354
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process4.56e-021.00e+004.4251119
GO:0048863stem cell differentiation4.56e-021.00e+004.4251119
GO:0007088regulation of mitosis4.56e-021.00e+004.4251119
GO:0044822poly(A) RNA binding4.59e-021.00e+001.1836501078
GO:0005525GTP binding4.60e-021.00e+001.900311328
GO:0048873homeostasis of number of cells within a tissue4.79e-021.00e+004.3511120
GO:0032402melanosome transport4.79e-021.00e+004.3511120
GO:0005680anaphase-promoting complex4.79e-021.00e+004.3511420
GO:0005719nuclear euchromatin4.79e-021.00e+004.3511220
GO:0015035protein disulfide oxidoreductase activity5.03e-021.00e+004.2801121
GO:0071364cellular response to epidermal growth factor stimulus5.03e-021.00e+004.2801121
GO:0004364glutathione transferase activity5.03e-021.00e+004.2801121
GO:0006457protein folding5.15e-021.00e+002.45328149
GO:0033574response to testosterone5.26e-021.00e+004.2131222
GO:0030863cortical cytoskeleton5.26e-021.00e+004.2131122
GO:0036464cytoplasmic ribonucleoprotein granule5.26e-021.00e+004.2131422
GO:0007052mitotic spindle organization5.26e-021.00e+004.2131222
GO:0031463Cul3-RING ubiquitin ligase complex5.49e-021.00e+004.1491223
GO:0043236laminin binding5.49e-021.00e+004.1491123
GO:0006513protein monoubiquitination5.49e-021.00e+004.1491123
GO:0005640nuclear outer membrane5.49e-021.00e+004.1491123
GO:0003723RNA binding5.58e-021.00e+001.786319355
GO:0006206pyrimidine nucleobase metabolic process5.72e-021.00e+004.0881224
GO:0008536Ran GTPase binding5.95e-021.00e+004.0291225
GO:0005844polysome5.95e-021.00e+004.0291425
GO:0017144drug metabolic process5.95e-021.00e+004.0291125
GO:0070979protein K11-linked ubiquitination6.19e-021.00e+003.9721326
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia6.19e-021.00e+003.9721226
GO:0006730one-carbon metabolic process6.19e-021.00e+003.9721126
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding6.37e-021.00e+002.28025168
GO:0004003ATP-dependent DNA helicase activity6.42e-021.00e+003.9181327
GO:0034080CENP-A containing nucleosome assembly6.42e-021.00e+003.9181227
GO:0005637nuclear inner membrane6.65e-021.00e+003.8651128
GO:0019894kinesin binding6.65e-021.00e+003.8651128
GO:0031252cell leading edge6.87e-021.00e+003.8151329
GO:0019005SCF ubiquitin ligase complex6.87e-021.00e+003.8151129
GO:0003730mRNA 3'-UTR binding6.87e-021.00e+003.8151229
GO:0006749glutathione metabolic process6.87e-021.00e+003.8151129
GO:0003887DNA-directed DNA polymerase activity6.87e-021.00e+003.8151329
GO:0071897DNA biosynthetic process6.87e-021.00e+003.8151229
GO:00063707-methylguanosine mRNA capping7.10e-021.00e+003.7661430
GO:0051262protein tetramerization7.10e-021.00e+003.7661330
GO:0006360transcription from RNA polymerase I promoter7.10e-021.00e+003.7661430
GO:0048487beta-tubulin binding7.10e-021.00e+003.7661130
GO:0031625ubiquitin protein ligase binding7.18e-021.00e+002.181213180
GO:0007094mitotic spindle assembly checkpoint7.33e-021.00e+003.7181531
GO:0015629actin cytoskeleton7.39e-021.00e+002.15725183
GO:0006144purine nucleobase metabolic process7.56e-021.00e+003.6731232
GO:0031397negative regulation of protein ubiquitination7.56e-021.00e+003.6731132
GO:0034644cellular response to UV7.56e-021.00e+003.6731532
GO:0005876spindle microtubule8.01e-021.00e+003.5851334
GO:0034332adherens junction organization8.46e-021.00e+003.5031136
GO:0004221ubiquitin thiolesterase activity8.46e-021.00e+003.5031236
GO:0001895retina homeostasis8.46e-021.00e+003.5031136
GO:0051084'de novo' posttranslational protein folding8.69e-021.00e+003.4631437
GO:0018107peptidyl-threonine phosphorylation8.69e-021.00e+003.4631137
GO:0070527platelet aggregation8.91e-021.00e+003.4251238
GO:0050681androgen receptor binding8.91e-021.00e+003.4251438
GO:0006383transcription from RNA polymerase III promoter9.14e-021.00e+003.3871339
GO:0008026ATP-dependent helicase activity9.14e-021.00e+003.3871339
GO:0031490chromatin DNA binding9.14e-021.00e+003.3871239
GO:0042645mitochondrial nucleoid9.14e-021.00e+003.3871239
GO:0022627cytosolic small ribosomal subunit9.14e-021.00e+003.3871339
GO:0032092positive regulation of protein binding9.14e-021.00e+003.3871339
GO:0007595lactation9.14e-021.00e+003.3871239
GO:0000781chromosome, telomeric region9.36e-021.00e+003.3511240
GO:0043195terminal bouton9.58e-021.00e+003.3151141
GO:0030521androgen receptor signaling pathway9.58e-021.00e+003.3151241
GO:0006418tRNA aminoacylation for protein translation9.80e-021.00e+003.2801542
GO:0042147retrograde transport, endosome to Golgi9.80e-021.00e+003.2801342
GO:0014070response to organic cyclic compound1.00e-011.00e+003.2461343
GO:0048146positive regulation of fibroblast proliferation1.02e-011.00e+003.2131244
GO:0007286spermatid development1.02e-011.00e+003.2131144
GO:0003774motor activity1.02e-011.00e+003.2131244
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding1.02e-011.00e+003.2131244
GO:0050434positive regulation of viral transcription1.02e-011.00e+003.2131544
GO:0015030Cajal body1.05e-011.00e+003.1811245
GO:0043966histone H3 acetylation1.05e-011.00e+003.1811245
GO:0005622intracellular1.06e-011.00e+001.85225226
GO:0021762substantia nigra development1.07e-011.00e+003.1491146
GO:0000079regulation of cyclin-dependent protein serine/threonine kinase activity1.09e-011.00e+003.1181347
GO:0019003GDP binding1.11e-011.00e+003.0881248
GO:0003743translation initiation factor activity1.13e-011.00e+003.0581449
GO:0035690cellular response to drug1.16e-011.00e+003.0291250
GO:0042802identical protein binding1.18e-011.00e+001.318318491
GO:0008168methyltransferase activity1.20e-011.00e+002.9721152
GO:0044267cellular protein metabolic process1.20e-011.00e+001.306324495
GO:0090305nucleic acid phosphodiester bond hydrolysis1.24e-011.00e+002.9181254
GO:0051028mRNA transport1.24e-011.00e+002.9181254
GO:0000226microtubule cytoskeleton organization1.26e-011.00e+002.8911355
GO:0000932cytoplasmic mRNA processing body1.29e-011.00e+002.8651356
GO:0005874microtubule1.31e-011.00e+001.66126258
GO:0030097hemopoiesis1.33e-011.00e+002.8151358
GO:0008237metallopeptidase activity1.33e-011.00e+002.8151158
GO:0005840ribosome1.35e-011.00e+002.7901259
GO:0045216cell-cell junction organization1.35e-011.00e+002.7901259
GO:0005643nuclear pore1.35e-011.00e+002.7901459
GO:0006987activation of signaling protein activity involved in unfolded protein response1.41e-011.00e+002.7181262
GO:0019903protein phosphatase binding1.43e-011.00e+002.6951463
GO:0000776kinetochore1.43e-011.00e+002.6951463
GO:0042995cell projection1.43e-011.00e+002.6951663
GO:0030855epithelial cell differentiation1.48e-011.00e+002.6501465
GO:0006368transcription elongation from RNA polymerase II promoter1.52e-011.00e+002.6061667
GO:0006338chromatin remodeling1.54e-011.00e+002.5851468
GO:0019899enzyme binding1.57e-011.00e+001.503211288
GO:0034329cell junction assembly1.60e-011.00e+002.5231171
GO:0032355response to estradiol1.64e-011.00e+002.4831573
GO:0000785chromatin1.64e-011.00e+002.4831573
GO:0006767water-soluble vitamin metabolic process1.68e-011.00e+002.4441375
GO:0007265Ras protein signal transduction1.68e-011.00e+002.4441375
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process1.70e-011.00e+002.4251376
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis1.73e-011.00e+002.4061577
GO:0006766vitamin metabolic process1.75e-011.00e+002.3871378
GO:0006334nucleosome assembly1.77e-011.00e+002.3691479
GO:0005856cytoskeleton1.77e-011.00e+001.39228311
GO:0007565female pregnancy1.79e-011.00e+002.3511280
GO:0030968endoplasmic reticulum unfolded protein response1.81e-011.00e+002.3331281
GO:0019083viral transcription1.81e-011.00e+002.3331881
GO:0001889liver development1.83e-011.00e+002.3151382
GO:0019901protein kinase binding1.85e-011.00e+001.351221320
GO:0047485protein N-terminus binding1.91e-011.00e+002.2461486
GO:0045087innate immune response1.91e-011.00e+000.991320616
GO:0006415translational termination1.93e-011.00e+002.2301887
GO:0008283cell proliferation1.94e-011.00e+001.302212331
GO:0003682chromatin binding1.97e-011.00e+001.289212334
GO:0005777peroxisome1.99e-011.00e+002.1811290
GO:0000922spindle pole2.01e-011.00e+002.1651491
GO:0003690double-stranded DNA binding2.01e-011.00e+002.1651491
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II2.03e-011.00e+002.1491492
GO:0042470melanosome2.03e-011.00e+002.14911092
GO:0006928cellular component movement2.03e-011.00e+002.1491792
GO:0006414translational elongation2.05e-011.00e+002.13311193
GO:0051082unfolded protein binding2.08e-011.00e+002.1031695
GO:0001649osteoblast differentiation2.08e-011.00e+002.1031695
GO:0006364rRNA processing2.10e-011.00e+002.0881596
GO:0051015actin filament binding2.12e-011.00e+002.0731297
GO:0071456cellular response to hypoxia2.14e-011.00e+002.0581498
GO:0006614SRP-dependent cotranslational protein targeting to membrane2.26e-011.00e+001.97218104
GO:0014069postsynaptic density2.30e-011.00e+001.94511106
GO:0005815microtubule organizing center2.37e-011.00e+001.89114110
GO:0015630microtubule cytoskeleton2.41e-011.00e+001.86515112
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay2.45e-011.00e+001.840110114
GO:0005819spindle2.45e-011.00e+001.84017114
GO:0005635nuclear envelope2.48e-011.00e+001.81516116
GO:0072562blood microparticle2.48e-011.00e+001.81514116
GO:0005739mitochondrion2.53e-011.00e+000.6424241046
GO:0007219Notch signaling pathway2.65e-011.00e+001.70714125
GO:0009615response to virus2.78e-011.00e+001.62816132
GO:0003735structural constituent of ribosome2.94e-011.00e+001.53318141
GO:0007507heart development2.94e-011.00e+001.53315141
GO:0061024membrane organization3.02e-011.00e+001.48315146
GO:0008017microtubule binding3.09e-011.00e+001.44417150
GO:0046777protein autophosphorylation3.23e-011.00e+001.36913158
GO:0055114oxidation-reduction process3.31e-011.00e+000.763211481
GO:0045893positive regulation of transcription, DNA-templated3.36e-011.00e+000.745217487
GO:0006397mRNA processing3.41e-011.00e+001.27213169
GO:0030424axon3.46e-011.00e+001.24613172
GO:0016607nuclear speck3.51e-011.00e+001.22114175
GO:0004672protein kinase activity3.55e-011.00e+001.19712178
GO:0019904protein domain specific binding3.60e-011.00e+001.17316181
GO:0006367transcription initiation from RNA polymerase II promoter3.65e-011.00e+001.14918184
GO:0032403protein complex binding3.67e-011.00e+001.14117185
GO:0001701in utero embryonic development4.05e-011.00e+000.95816210
GO:0005759mitochondrial matrix4.38e-011.00e+000.808112233
GO:0006412translation4.41e-011.00e+000.796115235
GO:0003713transcription coactivator activity4.46e-011.00e+000.772110239
GO:0007399nervous system development4.54e-011.00e+000.73612245
GO:0043025neuronal cell body4.66e-011.00e+000.68414254
GO:0004842ubiquitin-protein transferase activity4.69e-011.00e+000.67314256
GO:0005794Golgi apparatus4.77e-011.00e+000.328214650
GO:0005102receptor binding4.85e-011.00e+000.60615268
GO:0046872metal ion binding4.89e-011.00e+000.1564241465
GO:0000166nucleotide binding4.90e-011.00e+000.58516272
GO:0006357regulation of transcription from RNA polymerase II promoter4.94e-011.00e+000.56916275
GO:0007283spermatogenesis4.95e-011.00e+000.56416276
GO:0007264small GTPase mediated signal transduction5.12e-011.00e+000.49313290
GO:0016567protein ubiquitination5.23e-011.00e+000.44915299
GO:0005743mitochondrial inner membrane5.24e-011.00e+000.44415300
GO:0008152metabolic process5.27e-011.00e+000.43415302
GO:0007411axon guidance5.55e-011.00e+000.31919327
GO:0043231intracellular membrane-bounded organelle5.61e-011.00e+000.29718332
GO:0043565sequence-specific DNA binding5.96e-011.00e+000.16114365
GO:0005925focal adhesion6.01e-011.00e+000.141118370
GO:0007155cell adhesion6.15e-011.00e+000.08818384
GO:0008284positive regulation of cell proliferation6.22e-011.00e+000.05818392
GO:0046982protein heterodimerization activity6.29e-011.00e+000.032111399
GO:0006508proteolysis6.39e-011.00e+00-0.00719410
GO:0006366transcription from RNA polymerase II promoter6.52e-011.00e+00-0.059112425
GO:0007596blood coagulation6.85e-011.00e+00-0.185114464
GO:0048471perinuclear region of cytoplasm7.29e-011.00e+00-0.358112523
GO:0008270zinc ion binding7.46e-011.00e+00-0.3872121067
GO:0006351transcription, DNA-templated7.60e-011.00e+00-0.3733251585
GO:0006355regulation of transcription, DNA-templated7.63e-011.00e+00-0.4362171104
GO:0042803protein homodimerization activity7.86e-011.00e+00-0.597111617
GO:0005789endoplasmic reticulum membrane7.96e-011.00e+00-0.640110636
GO:0045944positive regulation of transcription from RNA polymerase II promoter8.70e-011.00e+00-0.991119811
GO:0007165signal transduction9.09e-011.00e+00-1.219117950
GO:0005615extracellular space9.23e-011.00e+00-1.3081171010
GO:0003677DNA binding9.69e-011.00e+00-1.7271261351
GO:0005886plasma membrane1.00e+001.00e+00-2.7961382834