meta-int-snw-115703

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-55854 tai-screen-luciferase 4.880 1.80e-26 2.35e-04 4.05e-04 5 3
int-snw-115703 tai-screen-luciferase 7.396 8.79e-193 1.68e-10 8.31e-05 12 11
reg-snw-60 tai-screen-luciferase 4.243 1.88e-19 3.43e-03 4.71e-03 12 5
reg-snw-1964 tai-screen-luciferase 4.532 1.75e-22 1.10e-03 1.69e-03 7 6
reg-snw-1121 tai-screen-luciferase 4.707 1.91e-24 5.19e-04 8.44e-04 5 3
reg-snw-1500 tai-screen-luciferase 4.226 2.77e-19 3.65e-03 4.98e-03 9 7
reg-snw-821 tai-screen-luciferase 4.344 1.76e-20 2.34e-03 3.35e-03 11 4
reg-snw-51164 tai-screen-luciferase 4.586 4.41e-23 8.78e-04 1.37e-03 6 4
reg-snw-57120 tai-screen-luciferase 4.450 1.33e-21 1.54e-03 2.29e-03 12 6
tai-screen-luciferase-meta-int-snw-115703 subnetwork

Genes (44)

Gene Symbol Entrez Gene ID Frequency tai-screen-luciferase gene score Best subnetwork score Degree List-Gonzales GI Tai-Hits
RPS2 6187 16-3.2414.22613Yes-
DMD 1756 15-4.3384.24353--
COPA 1314 48-9.3955.672340YesYes
PAFAH1B1 5048 18-2.5834.58655Yes-
TNFRSF8 943 19-4.1064.45015--
EIF1AX 1964 14-3.0054.53243Yes-
CUL4B 8450 21-2.8095.269142--
HSF1 3297 46-4.1795.027209-Yes
ARFGEF1 10565 13-2.7224.34415--
CANX 821 17-1.9594.50465--
ARHGAP33 115703 9-3.0827.3965--
COPB2 9276 48-13.1689.06341YesYes
CKAP5 9793 46-7.2145.672130YesYes
RB1 5925 21-2.0854.707351--
EIF2S2 8894 31-4.3205.672103Yes-
ZC3H15 55854 143.2694.88011--
RPS16 6217 38-5.4444.880205--
CHM 1121 13-0.4834.7072--
CDC42 998 44-6.9604.707276YesYes
DCTN4 51164 13-1.8824.58619--
RPS6 6194 44-5.6038.046217Yes-
MRPS12 6183 35-5.4215.516341Yes-
RAN 5901 38-3.8094.325258YesYes
SERBP1 26135 35-4.6125.516106-Yes
CDC5L 988 34-3.4195.672155--
HES4 57801 19-4.1534.45010--
GOPC 57120 191.7494.45068--
CAPRIN1 4076 14-2.2264.68842--
RPS24 6229 46-7.0348.389217Yes-
RPS9 6203 45-7.1277.555140Yes-
RPS4X 6191 44-6.7477.555263Yes-
PES1 23481 162.9174.22691--
DNAJC10 54431 13-2.3494.34411--
COPZ1 22818 48-8.3019.06313YesYes
YEATS4 8089 14-4.4444.53218YesYes
WDR46 9277 31-4.2904.226101YesYes
EIF2S3 1968 14-3.1444.53213Yes-
RPS27A 6233 45-5.6318.389344Yes-
EIF3M 10480 184.4514.88055Yes-
SRF 6722 151.9944.24323--
ACTB 60 15-1.7164.24323--
CTNND1 1500 16-2.6514.22653Yes-
RPS26 6231 43-7.4788.04660Yes-
ARCN1 372 48-8.2329.063118YesYes

Interactions (106)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
CDC42 998 RPS27A 6233 pp -- int.I2D: SOURAV_MAPK_HIGH
TNFRSF8 943 RB1 5925 pd < reg.pazar.txt: no annot
RPS4X 6191 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
EIF2S2 8894 PES1 23481 pp -- int.I2D: YeastLow
PAFAH1B1 5048 ARFGEF1 10565 pd > reg.ITFP.txt: no annot
ACTB 60 RPS4X 6191 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
ACTB 60 CANX 821 pd < reg.ITFP.txt: no annot
COPA 1314 RB1 5925 pd <> reg.ITFP.txt: no annot
HSF1 3297 SRF 6722 pd <> reg.ITFP.txt: no annot
HSF1 3297 SRF 6722 pp -- int.Yu: muscle
COPA 1314 DCTN4 51164 pd > reg.ITFP.txt: no annot
CDC5L 988 CUL4B 8450 pd <> reg.ITFP.txt: no annot
RPS2 6187 RPS4X 6191 pp -- int.I2D: YeastHigh, YeastMedium, INTEROLOG
ACTB 60 RPS9 6203 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RPS6 6194 RPS26 6231 pp -- int.I2D: YeastLow
ARCN1 372 RAN 5901 pp -- int.I2D: YeastLow
RB1 5925 GOPC 57120 pd > reg.ITFP.txt: no annot
CANX 821 ARFGEF1 10565 pd > reg.ITFP.txt: no annot
CANX 821 CAPRIN1 4076 pd > reg.ITFP.txt: no annot
RB1 5925 HES4 57801 pd > reg.pazar.txt: no annot
CHM 1121 COPA 1314 pd < reg.ITFP.txt: no annot
RPS9 6203 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
EIF1AX 1964 EIF2S3 1968 pd > reg.ITFP.txt: no annot
RB1 5925 SERBP1 26135 pd > reg.pazar.txt: no annot
RPS9 6203 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
ACTB 60 MRPS12 6183 pp -- int.I2D: BioGrid_Yeast
MRPS12 6183 RPS2 6187 pp -- int.I2D: YeastMedium
ACTB 60 RPS24 6229 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RPS4X 6191 PES1 23481 pp -- int.I2D: IntAct_Yeast
RPS27A 6233 ARFGEF1 10565 pp -- int.I2D: YeastLow
RPS6 6194 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
CUL4B 8450 GOPC 57120 pd > reg.ITFP.txt: no annot
RPS4X 6191 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
RPS2 6187 PES1 23481 pp -- int.I2D: IntAct_Yeast
PAFAH1B1 5048 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
PAFAH1B1 5048 GOPC 57120 pd > reg.ITFP.txt: no annot
EIF1AX 1964 RPS2 6187 pp -- int.I2D: YeastMedium
CAPRIN1 4076 CKAP5 9793 pd < reg.ITFP.txt: no annot
RPS2 6187 RPS9 6203 pp -- int.I2D: BIND_Yeast
RPS24 6229 PES1 23481 pp -- int.I2D: IntAct_Yeast
ACTB 60 EIF3M 10480 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
CDC42 998 ARFGEF1 10565 pp -- int.I2D: IntAct, SOURAV_MAPK_LOW
RPS2 6187 EIF3M 10480 pd < reg.ITFP.txt: no annot
CDC42 998 ARHGAP33 115703 pp -- int.I2D: MGI
RPS16 6217 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
CTNND1 1500 PES1 23481 pd <> reg.ITFP.txt: no annot
ACTB 60 RB1 5925 pd < reg.ITFP.txt: no annot
RPS4X 6191 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
EIF1AX 1964 YEATS4 8089 pd > reg.ITFP.txt: no annot
EIF1AX 1964 RPS9 6203 pp -- int.I2D: YeastMedium
ACTB 60 COPA 1314 pd < reg.ITFP.txt: no annot
ACTB 60 COPA 1314 pp -- int.I2D: BioGrid_Yeast
CAPRIN1 4076 CUL4B 8450 pd < reg.ITFP.txt: no annot
RPS6 6194 RPS27A 6233 pp -- int.I2D: YeastLow
RAN 5901 RPS2 6187 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
CDC5L 988 CKAP5 9793 pd <> reg.ITFP.txt: no annot
RPS16 6217 EIF3M 10480 pd < reg.ITFP.txt: no annot
RPS2 6187 RPS6 6194 pp -- int.I2D: BioGrid_Yeast
RAN 5901 WDR46 9277 pp -- int.I2D: YeastLow
PAFAH1B1 5048 DCTN4 51164 pd > reg.ITFP.txt: no annot
DMD 1756 SRF 6722 pd < reg.pazar.txt: no annot;
reg.TRANSFAC.txt: no annot
CANX 821 RB1 5925 pd <> reg.ITFP.txt: no annot
WDR46 9277 PES1 23481 pd <> reg.ITFP.txt: no annot
ACTB 60 RAN 5901 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, NON_CORE
ACTB 60 PAFAH1B1 5048 pp -- int.I2D: BioGrid_Yeast
COPA 1314 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
CANX 821 MRPS12 6183 pp -- int.I2D: BioGrid_Yeast
ACTB 60 EIF1AX 1964 pp -- int.I2D: BioGrid_Yeast
CDC42 998 GOPC 57120 pp -- int.I2D: BioGrid
COPA 1314 COPB2 9276 pp -- int.I2D: BioGrid, HPRD, BCI;
int.HPRD: in vivo
CANX 821 COPA 1314 pd <> reg.ITFP.txt: no annot
COPA 1314 CAPRIN1 4076 pd > reg.ITFP.txt: no annot
ACTB 60 ARCN1 372 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 EIF3M 10480 pd < reg.ITFP.txt: no annot
EIF1AX 1964 EIF2S2 8894 pp -- int.I2D: BioGrid_Yeast
CUL4B 8450 DNAJC10 54431 pd > reg.ITFP.txt: no annot
ACTB 60 YEATS4 8089 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
HSF1 3297 MRPS12 6183 pd <> reg.ITFP.txt: no annot
RB1 5925 DCTN4 51164 pd > reg.ITFP.txt: no annot
COPA 1314 GOPC 57120 pd > reg.ITFP.txt: no annot
CDC5L 988 GOPC 57120 pd > reg.ITFP.txt: no annot
CTNND1 1500 RPS2 6187 pd > reg.ITFP.txt: no annot
EIF1AX 1964 RPS16 6217 pp -- int.I2D: YeastMedium
RPS2 6187 RPS16 6217 pp -- int.I2D: INTEROLOG, YeastMedium, BioGrid_Yeast
CDC5L 988 COPA 1314 pd <> reg.ITFP.txt: no annot
COPA 1314 CUL4B 8450 pd <> reg.ITFP.txt: no annot
CDC5L 988 EIF2S2 8894 pd > reg.ITFP.txt: no annot
CHM 1121 RB1 5925 pd < reg.ITFP.txt: no annot
RPS6 6194 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
CANX 821 DCTN4 51164 pd > reg.ITFP.txt: no annot
ARCN1 372 COPA 1314 pp -- int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core;
int.HPRD: in vivo
EIF1AX 1964 EIF3M 10480 pd <> reg.ITFP.txt: no annot
CDC42 998 RB1 5925 pd < reg.pazar.txt: no annot
CANX 821 DNAJC10 54431 pd > reg.ITFP.txt: no annot
RPS4X 6191 RPS6 6194 pp -- int.I2D: BioGrid_Yeast
EIF3M 10480 ZC3H15 55854 pd > reg.ITFP.txt: no annot
CDC5L 988 RPS16 6217 pp -- int.I2D: BioGrid
COPA 1314 RPS27A 6233 pp -- int.I2D: YeastLow
RPS16 6217 RPS26 6231 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPB2 9276 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vivo
ACTB 60 SRF 6722 pd < reg.pazar.txt: no annot;
reg.oreganno.txt: no annot
RAN 5901 PES1 23481 pd < reg.ITFP.txt: no annot
EIF2S3 1968 EIF2S2 8894 pp -- int.Intact: MI:0407(direct interaction);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, MINT_Yeast, YeastHigh, Yu_GoldStd
RPS6 6194 PES1 23481 pp -- int.I2D: IntAct_Yeast
RPS24 6229 RPS27A 6233 pp -- int.I2D: YeastMedium
RPS27A 6233 EIF3M 10480 pd < reg.ITFP.txt: no annot
COPA 1314 PAFAH1B1 5048 pd <> reg.ITFP.txt: no annot

Related GO terms (648)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0006413translational initiation7.26e-161.18e-115.0871227131
GO:0015935small ribosomal subunit1.20e-141.95e-107.2557917
GO:0022627cytosolic small ribosomal subunit8.23e-141.34e-096.25082139
GO:0044822poly(A) RNA binding8.07e-131.32e-082.78320421078
GO:0006412translation8.42e-131.37e-084.2431229235
GO:0005829cytosol7.51e-121.23e-071.96727742562
GO:0019058viral life cycle1.80e-112.93e-074.859925115
GO:0019083viral transcription3.96e-116.47e-075.19582281
GO:0006415translational termination7.11e-111.16e-065.09282287
GO:0003735structural constituent of ribosome1.14e-101.85e-064.565924141
GO:0006414translational elongation1.23e-102.00e-064.99682293
GO:0006614SRP-dependent cotranslational protein targeting to membrane3.03e-104.95e-064.835822104
GO:0044267cellular protein metabolic process3.45e-105.64e-063.2841329495
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay6.35e-101.04e-054.702822114
GO:0016020membrane6.47e-101.06e-052.15721481746
GO:0048205COPI coating of Golgi vesicle3.23e-085.27e-046.8354613
GO:0030126COPI vesicle coat3.23e-085.27e-046.8354613
GO:0016071mRNA metabolic process1.24e-072.03e-033.734829223
GO:0010467gene expression1.29e-072.10e-032.7341236669
GO:0016070RNA metabolic process2.72e-074.44e-033.587829247
GO:0036464cytoplasmic ribonucleoprotein granule3.24e-075.29e-036.0764522
GO:0006890retrograde vesicle-mediated transport, Golgi to ER5.58e-079.10e-035.8914625
GO:0016032viral process1.30e-062.13e-022.7801037540
GO:0061024membrane organization2.47e-064.02e-023.930611146
GO:0042274ribosomal small subunit biogenesis3.95e-066.45e-026.5353612
GO:0003743translation initiation factor activity8.91e-061.45e-014.9204549
GO:0005515protein binding9.40e-061.53e-010.90831876127
GO:0008135translation factor activity, nucleic acid binding3.56e-055.80e-015.5353424
GO:0034332adherens junction organization1.23e-041.00e+004.9503436
GO:0006364rRNA processing1.27e-041.00e+003.9504896
GO:0043234protein complex1.44e-041.00e+002.89169300
GO:0007097nuclear migration1.48e-041.00e+006.728227
GO:0070062extracellular vesicular exosome1.56e-041.00e+001.32617512516
GO:0005737cytoplasm2.03e-041.00e+001.03722653976
GO:0030529ribonucleoprotein complex2.47e-041.00e+003.70248114
GO:0090136epithelial cell-cell adhesion2.53e-041.00e+006.365229
GO:0007067mitotic nuclear division3.77e-041.00e+003.00557231
GO:0005925focal adhesion4.44e-041.00e+002.589623370
GO:0005840ribosome5.35e-041.00e+004.23731059
GO:0035267NuA4 histone acetyltransferase complex6.33e-041.00e+005.7282214
GO:0048821erythrocyte development7.29e-041.00e+005.6282215
GO:0031369translation initiation factor binding7.29e-041.00e+005.6282215
GO:0050998nitric-oxide synthase binding8.32e-041.00e+005.5352316
GO:0075733intracellular transport of virus9.41e-041.00e+005.4482317
GO:0006891intra-Golgi vesicle-mediated transport9.41e-041.00e+005.4482317
GO:0017022myosin binding1.06e-031.00e+005.3652218
GO:0006886intracellular protein transport1.19e-031.00e+003.10046173
GO:0009306protein secretion1.44e-031.00e+005.1432221
GO:0005200structural constituent of cytoskeleton2.00e-031.00e+003.5813693
GO:0005844polysome2.05e-031.00e+004.8912225
GO:0019843rRNA binding2.39e-031.00e+004.7802427
GO:0030038contractile actin filament bundle assembly2.70e-031.00e+008.535111
GO:0045556positive regulation of TRAIL biosynthetic process2.70e-031.00e+008.535111
GO:0090287regulation of cellular response to growth factor stimulus2.70e-031.00e+008.535111
GO:0000235astral microtubule2.70e-031.00e+008.535111
GO:0090284positive regulation of protein glycosylation in Golgi2.70e-031.00e+008.535111
GO:0002183cytoplasmic translational initiation2.70e-031.00e+008.535111
GO:0090230regulation of centromere complex assembly2.70e-031.00e+008.535111
GO:0022605oogenesis stage2.70e-031.00e+008.535111
GO:0043004cytoplasmic sequestering of CFTR protein2.70e-031.00e+008.535111
GO:0021691cerebellar Purkinje cell layer maturation2.70e-031.00e+008.535111
GO:0051660establishment of centrosome localization2.70e-031.00e+008.535111
GO:0034975protein folding in endoplasmic reticulum2.70e-031.00e+008.535111
GO:0046016positive regulation of transcription by glucose2.70e-031.00e+008.535111
GO:0046469platelet activating factor metabolic process2.70e-031.00e+008.535111
GO:0007093mitotic cell cycle checkpoint3.14e-031.00e+004.5812231
GO:0051219phosphoprotein binding3.35e-031.00e+004.5352432
GO:0005730nucleolus4.22e-031.00e+001.27711361684
GO:0042059negative regulation of epidermal growth factor receptor signaling pathway4.22e-031.00e+004.3652336
GO:0050681androgen receptor binding4.70e-031.00e+004.2872238
GO:0021766hippocampus development4.94e-031.00e+004.2502339
GO:0010256endomembrane system organization5.38e-031.00e+007.535112
GO:0071987WD40-repeat domain binding5.38e-031.00e+007.535112
GO:0060661submandibular salivary gland formation5.38e-031.00e+007.535112
GO:0036035osteoclast development5.38e-031.00e+007.535112
GO:0014819regulation of skeletal muscle contraction5.38e-031.00e+007.535112
GO:0086001cardiac muscle cell action potential5.38e-031.00e+007.535112
GO:0071338positive regulation of hair follicle cell proliferation5.38e-031.00e+007.535112
GO:0051081nuclear envelope disassembly5.38e-031.00e+007.535112
GO:0002176male germ cell proliferation5.38e-031.00e+007.535112
GO:0000466maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)5.38e-031.00e+007.535112
GO:0072422signal transduction involved in DNA damage checkpoint5.38e-031.00e+007.535112
GO:0090135actin filament branching5.38e-031.00e+007.535112
GO:0031134sister chromatid biorientation5.38e-031.00e+007.535112
GO:0010736serum response element binding5.38e-031.00e+007.535112
GO:0007070negative regulation of transcription from RNA polymerase II promoter during mitosis5.38e-031.00e+007.535112
GO:0030521androgen receptor signaling pathway5.45e-031.00e+004.1772341
GO:0000086G2/M transition of mitotic cell cycle5.96e-031.00e+003.02236137
GO:0034613cellular protein localization6.25e-031.00e+004.0762244
GO:0021762substantia nigra development6.82e-031.00e+004.0112246
GO:0008344adult locomotory behavior7.11e-031.00e+003.9802247
GO:0000082G1/S transition of mitotic cell cycle7.65e-031.00e+002.891311150
GO:0007030Golgi organization8.02e-031.00e+003.8912350
GO:0001162RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding8.07e-031.00e+006.950113
GO:0014809regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion8.07e-031.00e+006.950113
GO:0060947cardiac vascular smooth muscle cell differentiation8.07e-031.00e+006.950113
GO:0003161cardiac conduction system development8.07e-031.00e+006.950113
GO:0071459protein localization to chromosome, centromeric region8.07e-031.00e+006.950113
GO:1900222negative regulation of beta-amyloid clearance8.07e-031.00e+006.950113
GO:1901385regulation of voltage-gated calcium channel activity8.07e-031.00e+006.950113
GO:0071930negative regulation of transcription involved in G1/S transition of mitotic cell cycle8.07e-031.00e+006.950113
GO:0045505dynein intermediate chain binding8.07e-031.00e+006.950113
GO:0051683establishment of Golgi localization8.07e-031.00e+006.950123
GO:0070545PeBoW complex8.07e-031.00e+006.950113
GO:0022028tangential migration from the subventricular zone to the olfactory bulb8.07e-031.00e+006.950113
GO:0000463maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)8.07e-031.00e+006.950113
GO:0016671oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor8.07e-031.00e+006.950113
GO:0030951establishment or maintenance of microtubule cytoskeleton polarity8.07e-031.00e+006.950113
GO:0033561regulation of water loss via skin8.07e-031.00e+006.950113
GO:0005850eukaryotic translation initiation factor 2 complex8.07e-031.00e+006.950113
GO:0000056ribosomal small subunit export from nucleus8.07e-031.00e+006.950123
GO:0034663endoplasmic reticulum chaperone complex8.07e-031.00e+006.950113
GO:1902083negative regulation of peptidyl-cysteine S-nitrosylation8.07e-031.00e+006.950123
GO:0021540corpus callosum morphogenesis8.07e-031.00e+006.950113
GO:0030687preribosome, large subunit precursor8.07e-031.00e+006.950113
GO:0030175filopodium8.97e-031.00e+003.8072253
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding1.04e-021.00e+002.72834168
GO:0019901protein kinase binding1.06e-021.00e+002.21349320
GO:0071922regulation of cohesin localization to chromatin1.07e-021.00e+006.535124
GO:0034191apolipoprotein A-I receptor binding1.07e-021.00e+006.535114
GO:0007000nucleolus organization1.07e-021.00e+006.535124
GO:0010669epithelial structure maintenance1.07e-021.00e+006.535114
GO:0060684epithelial-mesenchymal cell signaling1.07e-021.00e+006.535114
GO:0051835positive regulation of synapse structural plasticity1.07e-021.00e+006.535114
GO:0015036disulfide oxidoreductase activity1.07e-021.00e+006.535114
GO:0043550regulation of lipid kinase activity1.07e-021.00e+006.535114
GO:0016013syntrophin complex1.07e-021.00e+006.535124
GO:0090231regulation of spindle checkpoint1.07e-021.00e+006.535114
GO:0072384organelle transport along microtubule1.07e-021.00e+006.535124
GO:0003257positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation1.07e-021.00e+006.535114
GO:0048664neuron fate determination1.07e-021.00e+006.535114
GO:0010735positive regulation of transcription via serum response element binding1.07e-021.00e+006.535114
GO:0005968Rab-protein geranylgeranyltransferase complex1.07e-021.00e+006.535114
GO:0000055ribosomal large subunit export from nucleus1.07e-021.00e+006.535114
GO:0035189Rb-E2F complex1.07e-021.00e+006.535114
GO:0034088maintenance of mitotic sister chromatid cohesion1.07e-021.00e+006.535114
GO:0034349glial cell apoptotic process1.07e-021.00e+006.535114
GO:0045216cell-cell junction organization1.10e-021.00e+003.6522259
GO:0030424axon1.11e-021.00e+002.69434172
GO:0036336dendritic cell migration1.34e-021.00e+006.213115
GO:2000651positive regulation of sodium ion transmembrane transporter activity1.34e-021.00e+006.213115
GO:0035088establishment or maintenance of apical/basal cell polarity1.34e-021.00e+006.213115
GO:0000462maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)1.34e-021.00e+006.213135
GO:0048667cell morphogenesis involved in neuron differentiation1.34e-021.00e+006.213115
GO:0031256leading edge membrane1.34e-021.00e+006.213115
GO:0044233ER-mitochondrion membrane contact site1.34e-021.00e+006.213115
GO:0035912dorsal aorta morphogenesis1.34e-021.00e+006.213115
GO:0031465Cul4B-RING E3 ubiquitin ligase complex1.34e-021.00e+006.213115
GO:0043043peptide biosynthetic process1.34e-021.00e+006.213115
GO:0031023microtubule organizing center organization1.34e-021.00e+006.213115
GO:0033119negative regulation of RNA splicing1.34e-021.00e+006.213125
GO:0004663Rab geranylgeranyltransferase activity1.34e-021.00e+006.213115
GO:0034329cell junction assembly1.57e-021.00e+003.3852271
GO:0043353enucleate erythrocyte differentiation1.61e-021.00e+005.950116
GO:0007143female meiotic division1.61e-021.00e+005.950116
GO:0044458motile cilium assembly1.61e-021.00e+005.950116
GO:0002309T cell proliferation involved in immune response1.61e-021.00e+005.950116
GO:0045182translation regulator activity1.61e-021.00e+005.950126
GO:0051150regulation of smooth muscle cell differentiation1.61e-021.00e+005.950116
GO:0018344protein geranylgeranylation1.61e-021.00e+005.950116
GO:0060789hair follicle placode formation1.61e-021.00e+005.950116
GO:0008090retrograde axon cargo transport1.61e-021.00e+005.950116
GO:0051347positive regulation of transferase activity1.61e-021.00e+005.950116
GO:0048554positive regulation of metalloenzyme activity1.61e-021.00e+005.950116
GO:0045842positive regulation of mitotic metaphase/anaphase transition1.61e-021.00e+005.950116
GO:0001667ameboidal-type cell migration1.61e-021.00e+005.950116
GO:0000974Prp19 complex1.61e-021.00e+005.950116
GO:0030957Tat protein binding1.61e-021.00e+005.950116
GO:0034452dynactin binding1.61e-021.00e+005.950116
GO:0006924activation-induced cell death of T cells1.61e-021.00e+005.950126
GO:0003729mRNA binding1.65e-021.00e+003.3452373
GO:0000785chromatin1.65e-021.00e+003.3452273
GO:0003924GTPase activity1.73e-021.00e+002.45536203
GO:0031175neuron projection development1.74e-021.00e+003.3062275
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis1.83e-021.00e+003.2682477
GO:0060261positive regulation of transcription initiation from RNA polymerase II promoter1.87e-021.00e+005.728117
GO:0006893Golgi to plasma membrane transport1.87e-021.00e+005.728117
GO:0060055angiogenesis involved in wound healing1.87e-021.00e+005.728117
GO:0060136embryonic process involved in female pregnancy1.87e-021.00e+005.728117
GO:0043497regulation of protein heterodimerization activity1.87e-021.00e+005.728117
GO:0050658RNA transport1.87e-021.00e+005.728117
GO:0003334keratinocyte development1.87e-021.00e+005.728117
GO:0051988regulation of attachment of spindle microtubules to kinetochore1.87e-021.00e+005.728117
GO:0070914UV-damage excision repair1.87e-021.00e+005.728117
GO:0001961positive regulation of cytokine-mediated signaling pathway1.87e-021.00e+005.728117
GO:0000028ribosomal small subunit assembly1.87e-021.00e+005.728137
GO:0034101erythrocyte homeostasis1.87e-021.00e+005.728117
GO:0002162dystroglycan binding1.87e-021.00e+005.728117
GO:0030157pancreatic juice secretion1.87e-021.00e+005.728117
GO:0071541eukaryotic translation initiation factor 3 complex, eIF3m1.87e-021.00e+005.728117
GO:0017145stem cell division1.87e-021.00e+005.728117
GO:0000930gamma-tubulin complex1.87e-021.00e+005.728117
GO:0034259negative regulation of Rho GTPase activity1.87e-021.00e+005.728117
GO:0043197dendritic spine2.11e-021.00e+003.1602283
GO:0006184GTP catabolic process2.13e-021.00e+002.33936220
GO:0090009primitive streak formation2.14e-021.00e+005.535118
GO:0031512motile primary cilium2.14e-021.00e+005.535118
GO:0043589skin morphogenesis2.14e-021.00e+005.535118
GO:0007289spermatid nucleus differentiation2.14e-021.00e+005.535118
GO:0070688MLL5-L complex2.14e-021.00e+005.535118
GO:0005869dynactin complex2.14e-021.00e+005.535118
GO:0051489regulation of filopodium assembly2.14e-021.00e+005.535118
GO:0061003positive regulation of dendritic spine morphogenesis2.14e-021.00e+005.535118
GO:0000278mitotic cell cycle2.20e-021.00e+001.898416398
GO:0097284hepatocyte apoptotic process2.40e-021.00e+005.365119
GO:0000983RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity2.40e-021.00e+005.365119
GO:0000075cell cycle checkpoint2.40e-021.00e+005.365119
GO:0021895cerebral cortex neuron differentiation2.40e-021.00e+005.365119
GO:0005915zonula adherens2.40e-021.00e+005.365119
GO:0030837negative regulation of actin filament polymerization2.40e-021.00e+005.365119
GO:0032319regulation of Rho GTPase activity2.40e-021.00e+005.365119
GO:0045059positive thymic T cell selection2.40e-021.00e+005.365119
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II2.55e-021.00e+003.0112392
GO:0016363nuclear matrix2.55e-021.00e+003.0112492
GO:0042470melanosome2.55e-021.00e+003.0112292
GO:0005654nucleoplasm2.60e-021.00e+001.2467261095
GO:0002474antigen processing and presentation of peptide antigen via MHC class I2.65e-021.00e+002.9802794
GO:0034237protein kinase A regulatory subunit binding2.66e-021.00e+005.2131110
GO:0051787misfolded protein binding2.66e-021.00e+005.2131110
GO:0042535positive regulation of tumor necrosis factor biosynthetic process2.66e-021.00e+005.2131110
GO:0031274positive regulation of pseudopodium assembly2.66e-021.00e+005.2131210
GO:0001076RNA polymerase II transcription factor binding transcription factor activity2.66e-021.00e+005.2131110
GO:0090303positive regulation of wound healing2.66e-021.00e+005.2131110
GO:0061029eyelid development in camera-type eye2.66e-021.00e+005.2131110
GO:0001675acrosome assembly2.66e-021.00e+005.2131110
GO:0060218hematopoietic stem cell differentiation2.66e-021.00e+005.2131110
GO:0060047heart contraction2.66e-021.00e+005.2131110
GO:0030425dendrite2.67e-021.00e+002.21333240
GO:0001764neuron migration2.76e-021.00e+002.9502296
GO:0030426growth cone2.81e-021.00e+002.9352397
GO:0008134transcription factor binding2.85e-021.00e+002.17735246
GO:0045502dynein binding2.93e-021.00e+005.0761111
GO:0045176apical protein localization2.93e-021.00e+005.0761111
GO:0017166vinculin binding2.93e-021.00e+005.0761111
GO:0042551neuron maturation2.93e-021.00e+005.0761111
GO:0045651positive regulation of macrophage differentiation2.93e-021.00e+005.0761111
GO:0045120pronucleus2.93e-021.00e+005.0761111
GO:0035518histone H2A monoubiquitination2.93e-021.00e+005.0761211
GO:0002011morphogenesis of an epithelial sheet2.93e-021.00e+005.0761111
GO:0021819layer formation in cerebral cortex2.93e-021.00e+005.0761111
GO:0043025neuronal cell body3.09e-021.00e+002.13135254
GO:0007051spindle organization3.19e-021.00e+004.9501112
GO:0051146striated muscle cell differentiation3.19e-021.00e+004.9501212
GO:0043149stress fiber assembly3.19e-021.00e+004.9501212
GO:0019082viral protein processing3.19e-021.00e+004.9501212
GO:0030140trans-Golgi network transport vesicle3.19e-021.00e+004.9501112
GO:0043968histone H2A acetylation3.19e-021.00e+004.9501112
GO:0072583clathrin-mediated endocytosis3.19e-021.00e+004.9501112
GO:0047496vesicle transport along microtubule3.19e-021.00e+004.9501112
GO:0055003cardiac myofibril assembly3.19e-021.00e+004.9501112
GO:0014069postsynaptic density3.31e-021.00e+002.80723106
GO:0042789mRNA transcription from RNA polymerase II promoter3.45e-021.00e+004.8351113
GO:0001671ATPase activator activity3.45e-021.00e+004.8351113
GO:0043488regulation of mRNA stability3.45e-021.00e+004.8351113
GO:0033290eukaryotic 48S preinitiation complex3.45e-021.00e+004.8351113
GO:0042273ribosomal large subunit biogenesis3.45e-021.00e+004.8351113
GO:0031929TOR signaling3.45e-021.00e+004.8351113
GO:0032479regulation of type I interferon production3.45e-021.00e+004.8351213
GO:0005662DNA replication factor A complex3.45e-021.00e+004.8351113
GO:1900087positive regulation of G1/S transition of mitotic cell cycle3.45e-021.00e+004.8351113
GO:0060314regulation of ryanodine-sensitive calcium-release channel activity3.45e-021.00e+004.8351113
GO:0035855megakaryocyte development3.45e-021.00e+004.8351113
GO:0030496midbody3.49e-021.00e+002.76724109
GO:0035371microtubule plus-end3.71e-021.00e+004.7281114
GO:0031333negative regulation of protein complex assembly3.71e-021.00e+004.7281114
GO:0016282eukaryotic 43S preinitiation complex3.71e-021.00e+004.7281114
GO:0060292long term synaptic depression3.71e-021.00e+004.7281114
GO:0048488synaptic vesicle endocytosis3.71e-021.00e+004.7281114
GO:0031996thioesterase binding3.71e-021.00e+004.7281114
GO:0034185apolipoprotein binding3.71e-021.00e+004.7281114
GO:0043065positive regulation of apoptotic process3.74e-021.00e+002.02236274
GO:0030131clathrin adaptor complex3.97e-021.00e+004.6281115
GO:0002042cell migration involved in sprouting angiogenesis3.97e-021.00e+004.6281115
GO:0030225macrophage differentiation3.97e-021.00e+004.6281115
GO:0016514SWI/SNF complex3.97e-021.00e+004.6281115
GO:0045987positive regulation of smooth muscle contraction3.97e-021.00e+004.6281115
GO:0045445myoblast differentiation3.97e-021.00e+004.6281115
GO:0005852eukaryotic translation initiation factor 3 complex3.97e-021.00e+004.6281115
GO:0016010dystrophin-associated glycoprotein complex3.97e-021.00e+004.6281115
GO:2000114regulation of establishment of cell polarity3.97e-021.00e+004.6281115
GO:0051233spindle midzone3.97e-021.00e+004.6281215
GO:0048854brain morphogenesis3.97e-021.00e+004.6281115
GO:0060347heart trabecula formation3.97e-021.00e+004.6281115
GO:0032839dendrite cytoplasm4.23e-021.00e+004.5351116
GO:0007405neuroblast proliferation4.23e-021.00e+004.5351116
GO:0032012regulation of ARF protein signal transduction4.23e-021.00e+004.5351116
GO:0019226transmission of nerve impulse4.23e-021.00e+004.5351116
GO:0000132establishment of mitotic spindle orientation4.23e-021.00e+004.5351216
GO:0042176regulation of protein catabolic process4.23e-021.00e+004.5351416
GO:0033137negative regulation of peptidyl-serine phosphorylation4.23e-021.00e+004.5351116
GO:0030220platelet formation4.23e-021.00e+004.5351116
GO:0043623cellular protein complex assembly4.23e-021.00e+004.5351116
GO:0046716muscle cell cellular homeostasis4.23e-021.00e+004.5351116
GO:0030675Rac GTPase activator activity4.23e-021.00e+004.5351116
GO:0050775positive regulation of dendrite morphogenesis4.23e-021.00e+004.5351116
GO:0007264small GTPase mediated signal transduction4.31e-021.00e+001.94037290
GO:0006325chromatin organization4.34e-021.00e+002.59222123
GO:0051056regulation of small GTPase mediated signal transduction4.34e-021.00e+002.59223123
GO:0035255ionotropic glutamate receptor binding4.49e-021.00e+004.4481117
GO:0010880regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum4.49e-021.00e+004.4481117
GO:0033365protein localization to organelle4.49e-021.00e+004.4481117
GO:0043274phospholipase binding4.49e-021.00e+004.4481117
GO:0019068virion assembly4.49e-021.00e+004.4481217
GO:0008306associative learning4.49e-021.00e+004.4481117
GO:0031527filopodium membrane4.49e-021.00e+004.4481117
GO:0001829trophectodermal cell differentiation4.49e-021.00e+004.4481117
GO:0030742GTP-dependent protein binding4.49e-021.00e+004.4481117
GO:0001731formation of translation preinitiation complex4.49e-021.00e+004.4481117
GO:0030036actin cytoskeleton organization4.73e-021.00e+002.52423129
GO:0006612protein targeting to membrane4.75e-021.00e+004.3651218
GO:0045773positive regulation of axon extension4.75e-021.00e+004.3651118
GO:0005086ARF guanyl-nucleotide exchange factor activity4.75e-021.00e+004.3651118
GO:0090316positive regulation of intracellular protein transport4.75e-021.00e+004.3651118
GO:0030532small nuclear ribonucleoprotein complex4.75e-021.00e+004.3651118
GO:0000790nuclear chromatin4.99e-021.00e+002.48022133
GO:0006259DNA metabolic process5.00e-021.00e+004.2871119
GO:0007088regulation of mitosis5.00e-021.00e+004.2871119
GO:0017134fibroblast growth factor binding5.00e-021.00e+004.2871219
GO:0010881regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion5.00e-021.00e+004.2871119
GO:0048471perinuclear region of cytoplasm5.16e-021.00e+001.50449523
GO:2000134negative regulation of G1/S transition of mitotic cell cycle5.26e-021.00e+004.2131120
GO:0090398cellular senescence5.26e-021.00e+004.2131120
GO:0030544Hsp70 protein binding5.26e-021.00e+004.2131120
GO:0043473pigmentation5.26e-021.00e+004.2131220
GO:0043021ribonucleoprotein complex binding5.51e-021.00e+004.1431121
GO:0007369gastrulation5.51e-021.00e+004.1431121
GO:0015035protein disulfide oxidoreductase activity5.51e-021.00e+004.1431121
GO:0000793condensed chromosome5.51e-021.00e+004.1431221
GO:0043034costamere5.51e-021.00e+004.1431121
GO:0046847filopodium assembly5.51e-021.00e+004.1431121
GO:0005911cell-cell junction5.61e-021.00e+002.38522142
GO:0007220Notch receptor processing5.77e-021.00e+004.0761222
GO:0005790smooth endoplasmic reticulum5.77e-021.00e+004.0761122
GO:0031435mitogen-activated protein kinase kinase kinase binding5.77e-021.00e+004.0761122
GO:0000083regulation of transcription involved in G1/S transition of mitotic cell cycle5.77e-021.00e+004.0761122
GO:0030863cortical cytoskeleton5.77e-021.00e+004.0761122
GO:0007052mitotic spindle organization5.77e-021.00e+004.0761122
GO:0005525GTP binding5.82e-021.00e+001.76236328
GO:1900026positive regulation of substrate adhesion-dependent cell spreading6.02e-021.00e+004.0111123
GO:0051491positive regulation of filopodium assembly6.02e-021.00e+004.0111223
GO:0002040sprouting angiogenesis6.02e-021.00e+004.0111123
GO:0045879negative regulation of smoothened signaling pathway6.02e-021.00e+004.0111123
GO:0051017actin filament bundle assembly6.02e-021.00e+004.0111123
GO:0008060ARF GTPase activator activity6.02e-021.00e+004.0111123
GO:0001892embryonic placenta development6.02e-021.00e+004.0111123
GO:0051297centrosome organization6.02e-021.00e+004.0111223
GO:0043044ATP-dependent chromatin remodeling6.02e-021.00e+004.0111123
GO:0003682chromatin binding6.08e-021.00e+001.73634334
GO:0006457protein folding6.10e-021.00e+002.31623149
GO:0042981regulation of apoptotic process6.25e-021.00e+002.29727151
GO:0005761mitochondrial ribosome6.28e-021.00e+003.9501124
GO:0070059intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress6.28e-021.00e+003.9501124
GO:0007163establishment or maintenance of cell polarity6.28e-021.00e+003.9501224
GO:0046329negative regulation of JNK cascade6.28e-021.00e+003.9501124
GO:0005813centrosome6.30e-021.00e+001.71539339
GO:0006611protein export from nucleus6.53e-021.00e+003.8911125
GO:0032781positive regulation of ATPase activity6.53e-021.00e+003.8911125
GO:0070423nucleotide-binding oligomerization domain containing signaling pathway6.53e-021.00e+003.8911225
GO:0045296cadherin binding6.53e-021.00e+003.8911125
GO:0005788endoplasmic reticulum lumen6.69e-021.00e+002.24022157
GO:0045931positive regulation of mitotic cell cycle6.78e-021.00e+003.8351226
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia6.78e-021.00e+003.8351226
GO:0045214sarcomere organization6.78e-021.00e+003.8351126
GO:0045859regulation of protein kinase activity6.78e-021.00e+003.8351126
GO:0005978glycogen biosynthetic process6.78e-021.00e+003.8351226
GO:0048589developmental growth6.78e-021.00e+003.8351126
GO:0001707mesoderm formation6.78e-021.00e+003.8351126
GO:0043552positive regulation of phosphatidylinositol 3-kinase activity6.78e-021.00e+003.8351226
GO:0071556integral component of lumenal side of endoplasmic reticulum membrane6.78e-021.00e+003.8351126
GO:0005198structural molecule activity6.84e-021.00e+002.22225159
GO:0051149positive regulation of muscle cell differentiation7.03e-021.00e+003.7801227
GO:0032720negative regulation of tumor necrosis factor production7.03e-021.00e+003.7801127
GO:0007616long-term memory7.03e-021.00e+003.7801127
GO:0005083small GTPase regulator activity7.03e-021.00e+003.7801127
GO:0003723RNA binding7.03e-021.00e+001.648310355
GO:0031424keratinization7.03e-021.00e+003.7801127
GO:0048565digestive tract development7.03e-021.00e+003.7801127
GO:0031069hair follicle morphogenesis7.03e-021.00e+003.7801127
GO:0015031protein transport7.12e-021.00e+001.64034357
GO:0032467positive regulation of cytokinesis7.29e-021.00e+003.7281128
GO:0043967histone H4 acetylation7.29e-021.00e+003.7281228
GO:0031492nucleosomal DNA binding7.29e-021.00e+003.7281128
GO:0019894kinesin binding7.29e-021.00e+003.7281128
GO:0005875microtubule associated complex7.29e-021.00e+003.7281128
GO:0045597positive regulation of cell differentiation7.29e-021.00e+003.7281128
GO:0007017microtubule-based process7.29e-021.00e+003.7281228
GO:0031252cell leading edge7.54e-021.00e+003.6771329
GO:0003730mRNA 3'-UTR binding7.54e-021.00e+003.6771129
GO:0034605cellular response to heat7.54e-021.00e+003.6771129
GO:0072686mitotic spindle7.54e-021.00e+003.6771129
GO:0008285negative regulation of cell proliferation7.60e-021.00e+001.60033367
GO:0010977negative regulation of neuron projection development7.79e-021.00e+003.6281230
GO:0007346regulation of mitotic cell cycle7.79e-021.00e+003.6281330
GO:0031647regulation of protein stability7.79e-021.00e+003.6281130
GO:0002027regulation of heart rate7.79e-021.00e+003.6281230
GO:0040018positive regulation of multicellular organism growth7.79e-021.00e+003.6281130
GO:0010494cytoplasmic stress granule7.79e-021.00e+003.6281230
GO:0061077chaperone-mediated protein folding8.04e-021.00e+003.5811131
GO:0045211postsynaptic membrane8.23e-021.00e+002.06723177
GO:0032480negative regulation of type I interferon production8.28e-021.00e+003.5351232
GO:0031625ubiquitin protein ligase binding8.47e-021.00e+002.04324180
GO:0070830tight junction assembly8.53e-021.00e+003.4911133
GO:0033077T cell differentiation in thymus8.53e-021.00e+003.4911133
GO:0001569patterning of blood vessels8.78e-021.00e+003.4481134
GO:0007611learning or memory8.78e-021.00e+003.4481234
GO:0001890placenta development8.78e-021.00e+003.4481134
GO:0042692muscle cell differentiation8.78e-021.00e+003.4481234
GO:0048666neuron development9.02e-021.00e+003.4061135
GO:0071333cellular response to glucose stimulus9.02e-021.00e+003.4061235
GO:0009725response to hormone9.02e-021.00e+003.4061135
GO:0051402neuron apoptotic process9.27e-021.00e+003.3651136
GO:0032855positive regulation of Rac GTPase activity9.27e-021.00e+003.3651136
GO:0030433ER-associated ubiquitin-dependent protein catabolic process9.27e-021.00e+003.3651136
GO:0006446regulation of translational initiation9.27e-021.00e+003.3651236
GO:0001895retina homeostasis9.27e-021.00e+003.3651136
GO:0043547positive regulation of GTPase activity9.28e-021.00e+001.96524190
GO:0007173epidermal growth factor receptor signaling pathway9.37e-021.00e+001.95825191
GO:0001102RNA polymerase II activating transcription factor binding9.52e-021.00e+003.3261137
GO:0051084'de novo' posttranslational protein folding9.52e-021.00e+003.3261237
GO:0005791rough endoplasmic reticulum9.52e-021.00e+003.3261137
GO:0000139Golgi membrane9.70e-021.00e+001.44837408
GO:0001568blood vessel development9.76e-021.00e+003.2871238
GO:0070527platelet aggregation9.76e-021.00e+003.2871138
GO:0030049muscle filament sliding9.76e-021.00e+003.2871238
GO:0045740positive regulation of DNA replication9.76e-021.00e+003.2871138
GO:0032092positive regulation of protein binding1.00e-011.00e+003.2501139
GO:0031490chromatin DNA binding1.00e-011.00e+003.2501139
GO:0060048cardiac muscle contraction1.00e-011.00e+003.2501139
GO:0001933negative regulation of protein phosphorylation1.00e-011.00e+003.2501139
GO:0001228RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription1.02e-011.00e+003.2131140
GO:0051117ATPase binding1.05e-011.00e+003.1771241
GO:0008307structural constituent of muscle1.05e-011.00e+003.1771141
GO:0017148negative regulation of translation1.05e-011.00e+003.1771141
GO:0050885neuromuscular process controlling balance1.05e-011.00e+003.1771141
GO:0007249I-kappaB kinase/NF-kappaB signaling1.05e-011.00e+003.1771441
GO:0021987cerebral cortex development1.07e-011.00e+003.1431142
GO:0030155regulation of cell adhesion1.07e-011.00e+003.1431142
GO:0035914skeletal muscle cell differentiation1.07e-011.00e+003.1431142
GO:0035872nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway1.10e-011.00e+003.1091243
GO:0007286spermatid development1.12e-011.00e+003.0761144
GO:0005871kinesin complex1.12e-011.00e+003.0761144
GO:0050896response to stimulus1.12e-011.00e+003.0761144
GO:0016328lateral plasma membrane1.17e-011.00e+003.0111346
GO:0044297cell body1.17e-011.00e+003.0111146
GO:0043525positive regulation of neuron apoptotic process1.17e-011.00e+003.0111246
GO:0045727positive regulation of translation1.17e-011.00e+003.0111146
GO:0001047core promoter binding1.17e-011.00e+003.0111146
GO:0019003GDP binding1.22e-011.00e+002.9501148
GO:0001947heart looping1.24e-011.00e+002.9201149
GO:0034097response to cytokine1.26e-011.00e+002.8911150
GO:0001948glycoprotein binding1.26e-011.00e+002.8911250
GO:0005634nucleus1.26e-011.00e+000.38517664828
GO:0019221cytokine-mediated signaling pathway1.27e-011.00e+001.69025230
GO:0040008regulation of growth1.29e-011.00e+002.8631151
GO:0007254JNK cascade1.29e-011.00e+002.8631351
GO:0003684damaged DNA binding1.29e-011.00e+002.8631251
GO:0045732positive regulation of protein catabolic process1.29e-011.00e+002.8631151
GO:0006351transcription, DNA-templated1.30e-011.00e+000.7127171585
GO:0045454cell redox homeostasis1.31e-011.00e+002.8351152
GO:0034976response to endoplasmic reticulum stress1.31e-011.00e+002.8351152
GO:0016042lipid catabolic process1.31e-011.00e+002.8351252
GO:0006952defense response1.34e-011.00e+002.8071153
GO:0030666endocytic vesicle membrane1.36e-011.00e+002.7801254
GO:0051403stress-activated MAPK cascade1.36e-011.00e+002.7801454
GO:0019900kinase binding1.36e-011.00e+002.7801354
GO:0003713transcription coactivator activity1.36e-011.00e+001.63426239
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding1.36e-011.00e+002.7801154
GO:0050680negative regulation of epithelial cell proliferation1.36e-011.00e+002.7801154
GO:0000226microtubule cytoskeleton organization1.38e-011.00e+002.7541155
GO:0046330positive regulation of JNK cascade1.38e-011.00e+002.7541155
GO:0006888ER to Golgi vesicle-mediated transport1.38e-011.00e+002.7541155
GO:0000932cytoplasmic mRNA processing body1.41e-011.00e+002.7281156
GO:0003700sequence-specific DNA binding transcription factor activity1.41e-011.00e+000.98849748
GO:0045893positive regulation of transcription, DNA-templated1.43e-011.00e+001.19238487
GO:0016197endosomal transport1.45e-011.00e+002.6771358
GO:0051087chaperone binding1.47e-011.00e+002.6521159
GO:0005643nuclear pore1.47e-011.00e+002.6521159
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity1.47e-011.00e+002.6521159
GO:0010976positive regulation of neuron projection development1.50e-011.00e+002.6281260
GO:0032481positive regulation of type I interferon production1.52e-011.00e+002.6041361
GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity1.52e-011.00e+002.6041161
GO:0033138positive regulation of peptidyl-serine phosphorylation1.52e-011.00e+002.6041161
GO:0035091phosphatidylinositol binding1.52e-011.00e+002.6041161
GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription1.54e-011.00e+002.5811162
GO:0000776kinetochore1.57e-011.00e+002.5581363
GO:0006417regulation of translation1.57e-011.00e+002.5581463
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway1.59e-011.00e+002.5351264
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1.61e-011.00e+002.5131665
GO:0034146toll-like receptor 5 signaling pathway1.61e-011.00e+002.5131565
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.61e-011.00e+002.5131665
GO:0034166toll-like receptor 10 signaling pathway1.61e-011.00e+002.5131565
GO:0006469negative regulation of protein kinase activity1.61e-011.00e+002.5131165
GO:0071260cellular response to mechanical stimulus1.63e-011.00e+002.4911366
GO:0009636response to toxic substance1.63e-011.00e+002.4911166
GO:0031295T cell costimulation1.66e-011.00e+002.4691367
GO:0030141secretory granule1.66e-011.00e+002.4691267
GO:0006338chromatin remodeling1.68e-011.00e+002.4481268
GO:0045666positive regulation of neuron differentiation1.68e-011.00e+002.4481168
GO:0050790regulation of catalytic activity1.70e-011.00e+002.4261169
GO:0006887exocytosis1.70e-011.00e+002.4261169
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.73e-011.00e+002.4061870
GO:0035264multicellular organism growth1.73e-011.00e+002.4061170
GO:0045944positive regulation of transcription from RNA polymerase II promoter1.74e-011.00e+000.871411811
GO:0038123toll-like receptor TLR1:TLR2 signaling pathway1.75e-011.00e+002.3851571
GO:0038124toll-like receptor TLR6:TLR2 signaling pathway1.75e-011.00e+002.3851571
GO:0042383sarcolemma1.75e-011.00e+002.3851271
GO:0034162toll-like receptor 9 signaling pathway1.77e-011.00e+002.3651572
GO:0034134toll-like receptor 2 signaling pathway1.79e-011.00e+002.3451573
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent1.79e-011.00e+002.3451673
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.81e-011.00e+002.3261874
GO:0005085guanyl-nucleotide exchange factor activity1.81e-011.00e+002.3261174
GO:0007265Ras protein signal transduction1.84e-011.00e+002.3061375
GO:0060070canonical Wnt signaling pathway1.84e-011.00e+002.3061275
GO:0035666TRIF-dependent toll-like receptor signaling pathway1.86e-011.00e+002.2871576
GO:0044325ion channel binding1.88e-011.00e+002.2681377
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I1.88e-011.00e+002.2681677
GO:0008584male gonad development1.88e-011.00e+002.2681177
GO:0002756MyD88-independent toll-like receptor signaling pathway1.90e-011.00e+002.2501578
GO:0017137Rab GTPase binding1.90e-011.00e+002.2501178
GO:0071013catalytic step 2 spliceosome1.92e-011.00e+002.2311179
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.92e-011.00e+002.2311879
GO:0010629negative regulation of gene expression1.95e-011.00e+002.2131280
GO:0002755MyD88-dependent toll-like receptor signaling pathway1.95e-011.00e+002.2131580
GO:0034138toll-like receptor 3 signaling pathway1.95e-011.00e+002.2131580
GO:0045177apical part of cell1.99e-011.00e+002.1771182
GO:0030336negative regulation of cell migration2.01e-011.00e+002.1601283
GO:0007517muscle organ development2.01e-011.00e+002.1601183
GO:0005179hormone activity2.03e-011.00e+002.1431184
GO:0005856cytoskeleton2.04e-011.00e+001.25426311
GO:0047485protein N-terminus binding2.08e-011.00e+002.1091186
GO:0007160cell-matrix adhesion2.12e-011.00e+002.0761188
GO:0050852T cell receptor signaling pathway2.12e-011.00e+002.0761288
GO:0090090negative regulation of canonical Wnt signaling pathway2.12e-011.00e+002.0761388
GO:0042593glucose homeostasis2.14e-011.00e+002.0591189
GO:0000187activation of MAPK activity2.16e-011.00e+002.0431390
GO:0000922spindle pole2.18e-011.00e+002.0271591
GO:0018279protein N-linked glycosylation via asparagine2.18e-011.00e+002.0271191
GO:0016337single organismal cell-cell adhesion2.20e-011.00e+002.0111292
GO:0006928cellular component movement2.20e-011.00e+002.0111492
GO:0007411axon guidance2.20e-011.00e+001.18223327
GO:0016605PML body2.20e-011.00e+002.0111292
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activity2.23e-011.00e+001.9961193
GO:0005783endoplasmic reticulum2.26e-011.00e+000.86736610
GO:0051082unfolded protein binding2.27e-011.00e+001.9651195
GO:0034142toll-like receptor 4 signaling pathway2.29e-011.00e+001.9501596
GO:0045087innate immune response2.31e-011.00e+000.853311616
GO:0071456cellular response to hypoxia2.33e-011.00e+001.9201398
GO:0051726regulation of cell cycle2.41e-011.00e+001.86312102
GO:0004888transmembrane signaling receptor activity2.43e-011.00e+001.84911103
GO:0030054cell junction2.49e-011.00e+001.05924356
GO:0005096GTPase activator activity2.54e-011.00e+001.78013108
GO:0005794Golgi apparatus2.55e-011.00e+000.77638650
GO:0002224toll-like receptor signaling pathway2.56e-011.00e+001.76715109
GO:0005938cell cortex2.56e-011.00e+001.76711109
GO:0005815microtubule organizing center2.58e-011.00e+001.75414110
GO:0015630microtubule cytoskeleton2.62e-011.00e+001.72814112
GO:0005819spindle2.66e-011.00e+001.70214114
GO:0072562blood microparticle2.70e-011.00e+001.67711116
GO:0097190apoptotic signaling pathway2.70e-011.00e+001.67713116
GO:0000209protein polyubiquitination2.70e-011.00e+001.67717116
GO:0005802trans-Golgi network2.70e-011.00e+001.67712116
GO:0005635nuclear envelope2.70e-011.00e+001.67712116
GO:0006006glucose metabolic process2.76e-011.00e+001.64014119
GO:0032496response to lipopolysaccharide2.81e-011.00e+001.60411122
GO:0016192vesicle-mediated transport2.81e-011.00e+001.60411122
GO:0007568aging2.83e-011.00e+001.59212123
GO:0008284positive regulation of cell proliferation2.85e-011.00e+000.92027392
GO:0051092positive regulation of NF-kappaB transcription factor activity2.87e-011.00e+001.56913125
GO:0007219Notch signaling pathway2.87e-011.00e+001.56914125
GO:0007050cell cycle arrest2.89e-011.00e+001.55812126
GO:0006511ubiquitin-dependent protein catabolic process2.91e-011.00e+001.54613127
GO:0008201heparin binding2.91e-011.00e+001.54611127
GO:0030027lamellipodium2.97e-011.00e+001.51313130
GO:0007179transforming growth factor beta receptor signaling pathway2.97e-011.00e+001.51314130
GO:0046983protein dimerization activity2.99e-011.00e+001.50213131
GO:0045202synapse3.16e-011.00e+001.40611140
GO:0007507heart development3.18e-011.00e+001.39511141
GO:0016055Wnt signaling pathway3.18e-011.00e+001.39513141
GO:0008286insulin receptor signaling pathway3.23e-011.00e+001.36514144
GO:0043066negative regulation of apoptotic process3.26e-011.00e+000.777214433
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling3.31e-011.00e+001.32613148
GO:0010628positive regulation of gene expression3.32e-011.00e+001.31614149
GO:0008017microtubule binding3.34e-011.00e+001.30612150
GO:0001666response to hypoxia3.34e-011.00e+001.30611150
GO:0051260protein homooligomerization3.34e-011.00e+001.30612150
GO:0030246carbohydrate binding3.36e-011.00e+001.29711151
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription3.36e-011.00e+001.29712151
GO:0010008endosome membrane3.47e-011.00e+001.24012157
GO:0008543fibroblast growth factor receptor signaling pathway3.50e-011.00e+001.22213159
GO:0005886plasma membrane3.52e-011.00e+000.2369242834
GO:0043005neuron projection3.54e-011.00e+001.20416161
GO:0045121membrane raft3.54e-011.00e+001.20413161
GO:0008022protein C-terminus binding3.54e-011.00e+001.20414161
GO:0007596blood coagulation3.57e-011.00e+000.67725464
GO:0000398mRNA splicing, via spliceosome3.61e-011.00e+001.16912165
GO:0034220ion transmembrane transport3.64e-011.00e+001.15112167
GO:0007601visual perception3.66e-011.00e+001.14311168
GO:0038095Fc-epsilon receptor signaling pathway3.71e-011.00e+001.11713171
GO:0007420brain development3.73e-011.00e+001.10913172
GO:0016607nuclear speck3.78e-011.00e+001.08412175
GO:0031965nuclear membrane3.80e-011.00e+001.07612176
GO:0007049cell cycle3.81e-011.00e+001.06714177
GO:0042802identical protein binding3.83e-011.00e+000.59524491
GO:0019904protein domain specific binding3.88e-011.00e+001.03513181
GO:0043687post-translational protein modification3.88e-011.00e+001.03511181
GO:0015629actin cytoskeleton3.92e-011.00e+001.01913183
GO:0006367transcription initiation from RNA polymerase II promoter3.93e-011.00e+001.01115184
GO:0030168platelet activation4.27e-011.00e+000.85614205
GO:0001701in utero embryonic development4.35e-011.00e+000.82112210
GO:0000122negative regulation of transcription from RNA polymerase II promoter4.75e-011.00e+000.33329589
GO:0005509calcium ion binding4.75e-011.00e+000.33324589
GO:0007399nervous system development4.86e-011.00e+000.59811245
GO:0003677DNA binding5.00e-011.00e+000.1354141351
GO:0042803protein homodimerization activity5.00e-011.00e+000.26624617
GO:0006281DNA repair5.13e-011.00e+000.49115264
GO:0005102receptor binding5.18e-011.00e+000.46912268
GO:0000166nucleotide binding5.23e-011.00e+000.44812272
GO:0048011neurotrophin TRK receptor signaling pathway5.24e-011.00e+000.44215273
GO:0005975carbohydrate metabolic process5.26e-011.00e+000.43713274
GO:0003779actin binding5.27e-011.00e+000.43213275
GO:0007283spermatogenesis5.28e-011.00e+000.42612276
GO:0019899enzyme binding5.44e-011.00e+000.36515288
GO:0030198extracellular matrix organization5.52e-011.00e+000.33011295
GO:0006355regulation of transcription, DNA-templated5.79e-011.00e+000.0113101104
GO:0005575cellular_component5.84e-011.00e+000.20412322
GO:0030154cell differentiation5.88e-011.00e+000.19113325
GO:0008283cell proliferation5.95e-011.00e+000.16414331
GO:0043231intracellular membrane-bounded organelle5.96e-011.00e+000.16013332
GO:0007275multicellular organismal development6.09e-011.00e+000.10912344
GO:0007268synaptic transmission6.18e-011.00e+000.07111353
GO:0007155cell adhesion6.50e-011.00e+00-0.05013384
GO:0009986cell surface6.85e-011.00e+00-0.18611422
GO:0045892negative regulation of transcription, DNA-templated6.86e-011.00e+00-0.19312424
GO:0006366transcription from RNA polymerase II promoter6.87e-011.00e+00-0.19613425
GO:0008150biological_process7.15e-011.00e+00-0.30713459
GO:0006468protein phosphorylation7.22e-011.00e+00-0.33216467
GO:0055114oxidation-reduction process7.32e-011.00e+00-0.37512481
GO:0007165signal transduction7.35e-011.00e+00-0.35727950
GO:0055085transmembrane transport7.56e-011.00e+00-0.47113514
GO:0005615extracellular space7.66e-011.00e+00-0.445231010
GO:0046872metal ion binding7.68e-011.00e+00-0.3973141465
GO:0006915apoptotic process7.92e-011.00e+00-0.62219571
GO:0005789endoplasmic reticulum membrane8.26e-011.00e+00-0.77813636
GO:0044281small molecule metabolic process8.74e-011.00e+00-0.8042161295
GO:0005887integral component of plasma membrane9.31e-011.00e+00-1.37312961
GO:0008270zinc ion binding9.49e-011.00e+00-1.524171067
GO:0005524ATP binding9.78e-011.00e+00-1.8681191354
GO:0016021integral component of membrane9.99e-011.00e+00-2.743142483