reg-snw-821

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
tai-screen-luciferase 4.344 1.76e-20 2.34e-03 3.35e-03
tai-screen-luciferase-reg-snw-821 subnetwork

Genes (11)

Gene Symbol Entrez Gene ID Frequency tai-screen-luciferase gene score Best subnetwork score Degree Transcription factor List-Gonzales GI Tai-Hits
HES4 57801 3-4.1534.45010---
RB1 5925 5-2.0854.707351TF--
DNAJC10 54431 1-2.3494.34411---
CDC42 998 5-6.9604.70711-YesYes
COPA 1314 25-9.3955.672170TFYesYes
TNFRSF8 943 3-4.1064.45015---
CAPRIN1 4076 2-2.2264.68842---
ARFGEF1 10565 1-2.7224.34415---
[ CANX ] 821 3-1.9594.50465TF--
SERBP1 26135 10-4.6125.51643--Yes
CKAP5 9793 20-7.2145.67289TFYesYes

Interactions (12)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
CANX 821 COPA 1314 pd <> reg.ITFP.txt: no annot
CAPRIN1 4076 CKAP5 9793 pd < reg.ITFP.txt: no annot
CANX 821 DNAJC10 54431 pd > reg.ITFP.txt: no annot
COPA 1314 RB1 5925 pd <> reg.ITFP.txt: no annot
RB1 5925 HES4 57801 pd > reg.pazar.txt: no annot
CANX 821 ARFGEF1 10565 pd > reg.ITFP.txt: no annot
COPA 1314 CAPRIN1 4076 pd > reg.ITFP.txt: no annot
CANX 821 CAPRIN1 4076 pd > reg.ITFP.txt: no annot
CDC42 998 RB1 5925 pd < reg.pazar.txt: no annot
CANX 821 RB1 5925 pd <> reg.ITFP.txt: no annot
TNFRSF8 943 RB1 5925 pd < reg.pazar.txt: no annot
RB1 5925 SERBP1 26135 pd > reg.pazar.txt: no annot

Related GO terms (261)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0016020membrane9.10e-058.88e-012.3647251207
GO:0007030Golgi organization3.41e-041.00e+006.1502225
GO:0045556positive regulation of TRAIL biosynthetic process1.13e-031.00e+009.794111
GO:0090284positive regulation of protein glycosylation in Golgi1.13e-031.00e+009.794111
GO:0090230regulation of centromere complex assembly1.13e-031.00e+009.794111
GO:0015036disulfide oxidoreductase activity1.13e-031.00e+009.794111
GO:0031134sister chromatid biorientation1.13e-031.00e+009.794111
GO:0034975protein folding in endoplasmic reticulum1.13e-031.00e+009.794111
GO:0051683establishment of Golgi localization2.25e-031.00e+008.794112
GO:0071338positive regulation of hair follicle cell proliferation2.25e-031.00e+008.794112
GO:0010256endomembrane system organization2.25e-031.00e+008.794112
GO:0016671oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor2.25e-031.00e+008.794112
GO:0060661submandibular salivary gland formation2.25e-031.00e+008.794112
GO:0030951establishment or maintenance of microtubule cytoskeleton polarity2.25e-031.00e+008.794112
GO:0035088establishment or maintenance of apical/basal cell polarity2.25e-031.00e+008.794112
GO:0034663endoplasmic reticulum chaperone complex2.25e-031.00e+008.794112
GO:0051835positive regulation of synapse structural plasticity2.25e-031.00e+008.794112
GO:0090135actin filament branching2.25e-031.00e+008.794112
GO:0034088maintenance of mitotic sister chromatid cohesion2.25e-031.00e+008.794112
GO:0072384organelle transport along microtubule2.25e-031.00e+008.794112
GO:0007070negative regulation of transcription from RNA polymerase II promoter during mitosis2.25e-031.00e+008.794112
GO:0003161cardiac conduction system development3.38e-031.00e+008.209113
GO:0071459protein localization to chromosome, centromeric region3.38e-031.00e+008.209113
GO:0060684epithelial-mesenchymal cell signaling3.38e-031.00e+008.209113
GO:0044233ER-mitochondrion membrane contact site3.38e-031.00e+008.209113
GO:0071930negative regulation of transcription involved in G1/S transition of mitotic cell cycle3.38e-031.00e+008.209113
GO:0050658RNA transport4.50e-031.00e+007.794114
GO:0071922regulation of cohesin localization to chromatin4.50e-031.00e+007.794124
GO:0034191apolipoprotein A-I receptor binding4.50e-031.00e+007.794114
GO:0036336dendritic cell migration4.50e-031.00e+007.794114
GO:0048664neuron fate determination4.50e-031.00e+007.794114
GO:0030157pancreatic juice secretion4.50e-031.00e+007.794114
GO:0090136epithelial cell-cell adhesion4.50e-031.00e+007.794124
GO:0043550regulation of lipid kinase activity4.50e-031.00e+007.794114
GO:0031256leading edge membrane4.50e-031.00e+007.794114
GO:0035189Rb-E2F complex4.50e-031.00e+007.794114
GO:0034349glial cell apoptotic process4.50e-031.00e+007.794114
GO:0048554positive regulation of metalloenzyme activity4.50e-031.00e+007.794114
GO:0007097nuclear migration5.62e-031.00e+007.472125
GO:0031274positive regulation of pseudopodium assembly5.62e-031.00e+007.472115
GO:0003334keratinocyte development5.62e-031.00e+007.472115
GO:0045842positive regulation of mitotic metaphase/anaphase transition5.62e-031.00e+007.472115
GO:0061003positive regulation of dendritic spine morphogenesis5.62e-031.00e+007.472115
GO:0030837negative regulation of actin filament polymerization5.62e-031.00e+007.472115
GO:0048667cell morphogenesis involved in neuron differentiation5.62e-031.00e+007.472115
GO:0000930gamma-tubulin complex5.62e-031.00e+007.472115
GO:0034259negative regulation of Rho GTPase activity5.62e-031.00e+007.472115
GO:0005788endoplasmic reticulum lumen5.80e-031.00e+004.09422104
GO:0043353enucleate erythrocyte differentiation6.74e-031.00e+007.209116
GO:0034237protein kinase A regulatory subunit binding6.74e-031.00e+007.209116
GO:0001671ATPase activator activity6.74e-031.00e+007.209116
GO:0051489regulation of filopodium assembly6.74e-031.00e+007.209116
GO:0060789hair follicle placode formation6.74e-031.00e+007.209116
GO:0090303positive regulation of wound healing6.74e-031.00e+007.209116
GO:0000075cell cycle checkpoint6.74e-031.00e+007.209116
GO:0060047heart contraction6.74e-031.00e+007.209116
GO:0043497regulation of protein heterodimerization activity6.74e-031.00e+007.209116
GO:0051988regulation of attachment of spindle microtubules to kinetochore7.86e-031.00e+006.987117
GO:0030126COPI vesicle coat7.86e-031.00e+006.987117
GO:0051787misfolded protein binding8.98e-031.00e+006.794118
GO:0051233spindle midzone8.98e-031.00e+006.794118
GO:0042535positive regulation of tumor necrosis factor biosynthetic process8.98e-031.00e+006.794118
GO:0032012regulation of ARF protein signal transduction1.01e-021.00e+006.624119
GO:0031996thioesterase binding1.01e-021.00e+006.624119
GO:0072583clathrin-mediated endocytosis1.01e-021.00e+006.624119
GO:0097284hepatocyte apoptotic process1.01e-021.00e+006.624119
GO:2000114regulation of establishment of cell polarity1.01e-021.00e+006.624119
GO:0007051spindle organization1.12e-021.00e+006.4721110
GO:0042551neuron maturation1.12e-021.00e+006.4721110
GO:0045651positive regulation of macrophage differentiation1.12e-021.00e+006.4721110
GO:0043488regulation of mRNA stability1.12e-021.00e+006.4721110
GO:0048488synaptic vesicle endocytosis1.12e-021.00e+006.4721110
GO:0009306protein secretion1.23e-021.00e+006.3351211
GO:0031333negative regulation of protein complex assembly1.23e-021.00e+006.3351111
GO:0035255ionotropic glutamate receptor binding1.23e-021.00e+006.3351111
GO:0030225macrophage differentiation1.23e-021.00e+006.3351111
GO:0030742GTP-dependent protein binding1.23e-021.00e+006.3351111
GO:0090316positive regulation of intracellular protein transport1.23e-021.00e+006.3351111
GO:0005086ARF guanyl-nucleotide exchange factor activity1.23e-021.00e+006.3351111
GO:0008060ARF GTPase activator activity1.23e-021.00e+006.3351111
GO:0050775positive regulation of dendrite morphogenesis1.23e-021.00e+006.3351111
GO:0051297centrosome organization1.34e-021.00e+006.2091112
GO:0051146striated muscle cell differentiation1.34e-021.00e+006.2091212
GO:0030544Hsp70 protein binding1.34e-021.00e+006.2091112
GO:0007088regulation of mitosis1.34e-021.00e+006.2091112
GO:0048205COPI coating of Golgi vesicle1.34e-021.00e+006.2091112
GO:0035371microtubule plus-end1.46e-021.00e+006.0941113
GO:0045445myoblast differentiation1.46e-021.00e+006.0941113
GO:0034185apolipoprotein binding1.46e-021.00e+006.0941113
GO:0015035protein disulfide oxidoreductase activity1.46e-021.00e+006.0941113
GO:0016514SWI/SNF complex1.46e-021.00e+006.0941113
GO:0043025neuronal cell body1.51e-021.00e+003.37623171
GO:0046847filopodium assembly1.57e-021.00e+005.9871114
GO:0005790smooth endoplasmic reticulum1.57e-021.00e+005.9871114
GO:0042176regulation of protein catabolic process1.57e-021.00e+005.9871314
GO:0045859regulation of protein kinase activity1.57e-021.00e+005.9871114
GO:0032839dendrite cytoplasm1.68e-021.00e+005.8871115
GO:2000134negative regulation of G1/S transition of mitotic cell cycle1.68e-021.00e+005.8871115
GO:0032781positive regulation of ATPase activity1.68e-021.00e+005.8871115
GO:0045879negative regulation of smoothened signaling pathway1.68e-021.00e+005.8871115
GO:0051017actin filament bundle assembly1.68e-021.00e+005.8871115
GO:1900026positive regulation of substrate adhesion-dependent cell spreading1.79e-021.00e+005.7941116
GO:0032467positive regulation of cytokinesis1.79e-021.00e+005.7941116
GO:0017022myosin binding1.79e-021.00e+005.7941216
GO:0006890retrograde vesicle-mediated transport, Golgi to ER1.90e-021.00e+005.7071117
GO:0030532small nuclear ribonucleoprotein complex1.90e-021.00e+005.7071117
GO:0031435mitogen-activated protein kinase kinase kinase binding2.01e-021.00e+005.6241118
GO:0031069hair follicle morphogenesis2.01e-021.00e+005.6241118
GO:0048565digestive tract development2.12e-021.00e+005.5461119
GO:0071556integral component of lumenal side of endoplasmic reticulum membrane2.12e-021.00e+005.5461119
GO:0036464cytoplasmic ribonucleoprotein granule2.12e-021.00e+005.5461419
GO:0008134transcription factor binding2.21e-021.00e+003.08725209
GO:0070059intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress2.23e-021.00e+005.4721120
GO:0007163establishment or maintenance of cell polarity2.23e-021.00e+005.4721220
GO:0043234protein complex2.23e-021.00e+003.08028210
GO:0072686mitotic spindle2.23e-021.00e+005.4721120
GO:0031647regulation of protein stability2.34e-021.00e+005.4021121
GO:0007346regulation of mitotic cell cycle2.34e-021.00e+005.4021121
GO:0000083regulation of transcription involved in G1/S transition of mitotic cell cycle2.34e-021.00e+005.4021121
GO:0051149positive regulation of muscle cell differentiation2.45e-021.00e+005.3351222
GO:0043552positive regulation of phosphatidylinositol 3-kinase activity2.45e-021.00e+005.3351122
GO:0061077chaperone-mediated protein folding2.45e-021.00e+005.3351122
GO:0030433ER-associated ubiquitin-dependent protein catabolic process2.45e-021.00e+005.3351122
GO:0002040sprouting angiogenesis2.45e-021.00e+005.3351122
GO:0070062extracellular vesicular exosome2.53e-021.00e+001.4365281641
GO:0031424keratinization2.56e-021.00e+005.2701123
GO:0005791rough endoplasmic reticulum2.56e-021.00e+005.2701123
GO:0051117ATPase binding2.67e-021.00e+005.2091124
GO:0051219phosphoprotein binding2.78e-021.00e+005.1501325
GO:0007093mitotic cell cycle checkpoint2.78e-021.00e+005.1501225
GO:0003730mRNA 3'-UTR binding2.78e-021.00e+005.1501125
GO:0034613cellular protein localization2.89e-021.00e+005.0941226
GO:0010494cytoplasmic stress granule2.89e-021.00e+005.0941226
GO:0034332adherens junction organization3.11e-021.00e+004.9871328
GO:0042692muscle cell differentiation3.11e-021.00e+004.9871228
GO:0042059negative regulation of epidermal growth factor receptor signaling pathway3.11e-021.00e+004.9871228
GO:0051402neuron apoptotic process3.33e-021.00e+004.8871130
GO:0001933negative regulation of protein phosphorylation3.33e-021.00e+004.8871130
GO:0050681androgen receptor binding3.33e-021.00e+004.8871230
GO:0001102RNA polymerase II activating transcription factor binding3.44e-021.00e+004.8401131
GO:0034976response to endoplasmic reticulum stress3.44e-021.00e+004.8401131
GO:0045454cell redox homeostasis3.44e-021.00e+004.8401131
GO:0000139Golgi membrane3.48e-021.00e+002.73324267
GO:0019900kinase binding3.55e-021.00e+004.7941232
GO:0045740positive regulation of DNA replication3.55e-021.00e+004.7941132
GO:0005829cytosol3.56e-021.00e+001.3135331787
GO:0035914skeletal muscle cell differentiation3.66e-021.00e+004.7501133
GO:0017148negative regulation of translation3.66e-021.00e+004.7501133
GO:0021762substantia nigra development3.77e-021.00e+004.7071234
GO:0046330positive regulation of JNK cascade3.77e-021.00e+004.7071134
GO:0030521androgen receptor signaling pathway3.87e-021.00e+004.6651335
GO:0001948glycoprotein binding4.09e-021.00e+004.5851137
GO:0030175filopodium4.09e-021.00e+004.5851237
GO:0050680negative regulation of epithelial cell proliferation4.31e-021.00e+004.5091139
GO:0005840ribosome4.42e-021.00e+004.4721340
GO:0043525positive regulation of neuron apoptotic process4.53e-021.00e+004.4361241
GO:0001047core promoter binding4.63e-021.00e+004.4021142
GO:0000278mitotic cell cycle4.68e-021.00e+002.49929314
GO:0005085guanyl-nucleotide exchange factor activity4.74e-021.00e+004.3681143
GO:0000932cytoplasmic mRNA processing body4.74e-021.00e+004.3681143
GO:0006887exocytosis4.85e-021.00e+004.3351144
GO:0030141secretory granule4.85e-021.00e+004.3351244
GO:0005737cytoplasm4.86e-021.00e+001.0166392633
GO:0051087chaperone binding4.96e-021.00e+004.3021145
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity4.96e-021.00e+004.3021145
GO:0033138positive regulation of peptidyl-serine phosphorylation5.28e-021.00e+004.2091148
GO:0044822poly(A) RNA binding5.48e-021.00e+001.737325799
GO:0006469negative regulation of protein kinase activity5.49e-021.00e+004.1501150
GO:0048471perinuclear region of cytoplasm5.52e-021.00e+002.36827344
GO:0060070canonical Wnt signaling pathway5.60e-021.00e+004.1221251
GO:0031295T cell costimulation5.60e-021.00e+004.1221151
GO:0043197dendritic spine5.60e-021.00e+004.1221251
GO:0042802identical protein binding5.81e-021.00e+002.32622354
GO:0045177apical part of cell5.92e-021.00e+004.0391154
GO:0035264multicellular organism growth5.92e-021.00e+004.0391154
GO:0071260cellular response to mechanical stimulus6.03e-021.00e+004.0131155
GO:0006338chromatin remodeling6.03e-021.00e+004.0131255
GO:0031175neuron projection development6.03e-021.00e+004.0131255
GO:0000785chromatin6.45e-021.00e+003.9111259
GO:0007265Ras protein signal transduction6.45e-021.00e+003.9111259
GO:0005179hormone activity6.56e-021.00e+003.8871160
GO:0005783endoplasmic reticulum6.62e-021.00e+002.22023381
GO:0018279protein N-linked glycosylation via asparagine6.66e-021.00e+003.8631161
GO:0010629negative regulation of gene expression6.77e-021.00e+003.8401262
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II6.98e-021.00e+003.7941364
GO:0042470melanosome6.98e-021.00e+003.7941264
GO:0004888transmembrane signaling receptor activity7.30e-021.00e+003.7281167
GO:0000922spindle pole7.40e-021.00e+003.7071368
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis7.61e-021.00e+003.6651370
GO:0051082unfolded protein binding7.61e-021.00e+003.6651170
GO:0002474antigen processing and presentation of peptide antigen via MHC class I7.61e-021.00e+003.6651470
GO:0016192vesicle-mediated transport7.72e-021.00e+003.6441171
GO:0030496midbody7.93e-021.00e+003.6041373
GO:0016363nuclear matrix7.93e-021.00e+003.6041273
GO:0005802trans-Golgi network8.03e-021.00e+003.5851174
GO:0015630microtubule cytoskeleton8.14e-021.00e+003.5651275
GO:0051056regulation of small GTPase mediated signal transduction8.24e-021.00e+003.5461176
GO:0005815microtubule organizing center8.34e-021.00e+003.5271277
GO:0016605PML body8.55e-021.00e+003.4901179
GO:0030246carbohydrate binding8.66e-021.00e+003.4721180
GO:0005819spindle8.66e-021.00e+003.4721280
GO:0006886intracellular protein transport9.59e-021.00e+003.3181189
GO:0061024membrane organization9.59e-021.00e+003.3181389
GO:0030036actin cytoskeleton organization9.69e-021.00e+003.3021290
GO:0007050cell cycle arrest9.89e-021.00e+003.2701292
GO:0046983protein dimerization activity1.01e-011.00e+003.2391294
GO:0000086G2/M transition of mitotic cell cycle1.04e-011.00e+003.1941397
GO:0006457protein folding1.04e-011.00e+003.1941297
GO:0007568aging1.04e-011.00e+003.1941197
GO:0005198structural molecule activity1.08e-011.00e+003.13611101
GO:0005911cell-cell junction1.11e-011.00e+003.09412104
GO:0010628positive regulation of gene expression1.13e-011.00e+003.06612106
GO:0042981regulation of apoptotic process1.19e-011.00e+002.98714112
GO:0043547positive regulation of GTPase activity1.19e-011.00e+002.98714112
GO:0043005neuron projection1.20e-011.00e+002.97412113
GO:0043687post-translational protein modification1.23e-011.00e+002.93611116
GO:0003924GTPase activity1.26e-011.00e+002.89913119
GO:0005515protein binding1.29e-011.00e+000.5917504124
GO:0000082G1/S transition of mitotic cell cycle1.32e-011.00e+002.82816125
GO:0030424axon1.35e-011.00e+002.79414128
GO:0006184GTP catabolic process1.37e-011.00e+002.77213130
GO:0031625ubiquitin protein ligase binding1.45e-011.00e+002.68512138
GO:0007173epidermal growth factor receptor signaling pathway1.49e-011.00e+002.64413142
GO:0007399nervous system development1.59e-011.00e+002.54611152
GO:0007067mitotic nuclear division1.71e-011.00e+002.42815165
GO:0030425dendrite1.72e-011.00e+002.41913166
GO:0007264small GTPase mediated signal transduction1.80e-011.00e+002.35114174
GO:0003713transcription coactivator activity1.89e-011.00e+002.27013184
GO:0005525GTP binding2.01e-011.00e+002.17213197
GO:0043065positive regulation of apoptotic process2.06e-011.00e+002.13613202
GO:0015031protein transport2.06e-011.00e+002.12912203
GO:0030154cell differentiation2.07e-011.00e+002.12212204
GO:0005813centrosome2.19e-011.00e+002.03216217
GO:0019901protein kinase binding2.33e-011.00e+001.93618232
GO:0007411axon guidance2.37e-011.00e+001.90512237
GO:0003723RNA binding2.46e-011.00e+001.84616247
GO:0008285negative regulation of cell proliferation2.71e-011.00e+001.68013277
GO:0005925focal adhesion2.76e-011.00e+001.654112282
GO:0003677DNA binding2.90e-011.00e+000.907212947
GO:0055114oxidation-reduction process2.97e-011.00e+001.52711308
GO:0045892negative regulation of transcription, DNA-templated3.05e-011.00e+001.48611317
GO:0007596blood coagulation3.22e-011.00e+001.38914339
GO:0005886plasma membrane3.25e-011.00e+000.5783131784
GO:0005509calcium ion binding3.32e-011.00e+001.33913351
GO:0044267cellular protein metabolic process3.32e-011.00e+001.335113352
GO:0006351transcription, DNA-templated3.46e-011.00e+000.7232151076
GO:0045893positive regulation of transcription, DNA-templated3.52e-011.00e+001.23616377
GO:0005789endoplasmic reticulum membrane3.59e-011.00e+001.19813387
GO:0005794Golgi apparatus3.80e-011.00e+001.09713415
GO:0016032viral process3.89e-011.00e+001.053113428
GO:0045087innate immune response4.06e-011.00e+000.97416452
GO:0005887integral component of plasma membrane4.87e-011.00e+000.62711575
GO:0003700sequence-specific DNA binding transcription factor activity4.92e-011.00e+000.60919582
GO:0007165signal transduction5.13e-011.00e+000.52315618
GO:0005634nucleus5.25e-011.00e+000.1304403246
GO:0045944positive regulation of transcription from RNA polymerase II promoter5.28e-011.00e+000.46318644
GO:0005615extracellular space5.32e-011.00e+000.44712651
GO:0006355regulation of transcription, DNA-templated5.67e-011.00e+000.31219715
GO:0005654nucleoplasm6.45e-011.00e+000.019116876
GO:0005730nucleolus7.69e-011.00e+00-0.4551211217
GO:0016021integral component of membrane8.46e-011.00e+00-0.782131526