reg-snw-1500

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
tai-screen-luciferase	4.226	2.77e-19	3.65e-03	4.98e-03

tai-screen-luciferase-reg-snw-1500 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	tai-screen-luciferase gene score	Best subnetwork score	Degree	Transcription factor	List-Gonzales GI	Tai-Hits
PES1	23481	1	2.917	4.226	91	TF	-	-
RPS16	6217	3	-5.444	4.880	3	-	-	-
RPS2	6187	1	-3.241	4.226	13	-	Yes	-
WDR46	9277	1	-4.290	4.226	14	TF	Yes	Yes
RPS27A	6233	3	-5.631	4.880	2	-	Yes	-
RPS6	6194	3	-5.603	4.880	9	-	Yes	-
EIF3M	10480	3	4.451	4.880	55	TF	Yes	-
[ CTNND1 ]	1500	1	-2.651	4.226	53	TF	Yes	-
RAN	5901	2	-3.809	4.325	83	-	Yes	Yes

Interactions (8)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
WDR46	9277	PES1	23481	pd	<>	reg.ITFP.txt: no annot
CTNND1	1500	RPS2	6187	pd	>	reg.ITFP.txt: no annot
RPS27A	6233	EIF3M	10480	pd	<	reg.ITFP.txt: no annot
RPS16	6217	EIF3M	10480	pd	<	reg.ITFP.txt: no annot
RPS2	6187	EIF3M	10480	pd	<	reg.ITFP.txt: no annot
RPS6	6194	EIF3M	10480	pd	<	reg.ITFP.txt: no annot
CTNND1	1500	PES1	23481	pd	<>	reg.ITFP.txt: no annot
RAN	5901	PES1	23481	pd	<	reg.ITFP.txt: no annot

Related GO terms (189)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0019058	viral life cycle	3.51e-09	3.43e-05	6.120	5	8	78
GO:0022627	cytosolic small ribosomal subunit	9.02e-09	8.81e-05	7.177	4	6	30
GO:0006413	translational initiation	1.18e-08	1.15e-04	5.776	5	12	99
GO:0015935	small ribosomal subunit	1.19e-07	1.16e-03	8.083	3	4	12
GO:0019083	viral transcription	1.70e-07	1.66e-03	6.153	4	7	61
GO:0006415	translational termination	1.93e-07	1.89e-03	6.106	4	7	63
GO:0006414	translational elongation	2.80e-07	2.74e-03	5.975	4	7	69
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	4.37e-07	4.27e-03	5.817	4	7	77
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	6.21e-07	6.07e-03	5.691	4	7	84
GO:0044822	poly(A) RNA binding	7.45e-07	7.27e-03	3.249	7	25	799
GO:0003735	structural constituent of ribosome	1.77e-06	1.73e-02	5.315	4	8	109
GO:0016071	mRNA metabolic process	1.04e-05	1.02e-01	4.674	4	11	170
GO:0006412	translation	1.25e-05	1.22e-01	4.608	4	13	178
GO:0016070	RNA metabolic process	1.55e-05	1.52e-01	4.529	4	11	188
GO:0075733	intracellular transport of virus	1.58e-05	1.54e-01	8.276	2	2	7
GO:0016032	viral process	1.72e-05	1.68e-01	3.664	5	13	428
GO:0006364	rRNA processing	2.52e-05	2.46e-01	5.602	3	5	67
GO:0042274	ribosomal small subunit biogenesis	4.14e-05	4.04e-01	7.624	2	3	11
GO:0010467	gene expression	5.08e-05	4.96e-01	3.342	5	17	535
GO:0044267	cellular protein metabolic process	1.81e-04	1.00e+00	3.624	4	13	352
GO:0016020	membrane	2.12e-04	1.00e+00	2.431	6	25	1207
GO:0002183	cytoplasmic translational initiation	9.22e-04	1.00e+00	10.083	1	1	1
GO:0022605	oogenesis stage	9.22e-04	1.00e+00	10.083	1	1	1
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.84e-03	1.00e+00	9.083	1	1	2
GO:0005829	cytosol	1.88e-03	1.00e+00	1.865	6	33	1787
GO:0000056	ribosomal small subunit export from nucleus	2.76e-03	1.00e+00	8.499	1	1	3
GO:0070545	PeBoW complex	2.76e-03	1.00e+00	8.499	1	1	3
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.76e-03	1.00e+00	8.499	1	1	3
GO:0030687	preribosome, large subunit precursor	2.76e-03	1.00e+00	8.499	1	1	3
GO:0000055	ribosomal large subunit export from nucleus	3.68e-03	1.00e+00	8.083	1	1	4
GO:0007000	nucleolus organization	3.68e-03	1.00e+00	8.083	1	2	4
GO:0019082	viral protein processing	3.68e-03	1.00e+00	8.083	1	1	4
GO:0000028	ribosomal small subunit assembly	4.60e-03	1.00e+00	7.762	1	3	5
GO:0002309	T cell proliferation involved in immune response	4.60e-03	1.00e+00	7.762	1	1	5
GO:0051347	positive regulation of transferase activity	5.52e-03	1.00e+00	7.499	1	1	6
GO:0005915	zonula adherens	5.52e-03	1.00e+00	7.499	1	1	6
GO:0006924	activation-induced cell death of T cells	5.52e-03	1.00e+00	7.499	1	2	6
GO:0000082	G1/S transition of mitotic cell cycle	5.52e-03	1.00e+00	4.118	2	6	125
GO:0005654	nucleoplasm	5.61e-03	1.00e+00	2.309	4	16	876
GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m	6.44e-03	1.00e+00	7.276	1	1	7
GO:0019068	virion assembly	6.44e-03	1.00e+00	7.276	1	1	7
GO:0031929	TOR signaling	8.27e-03	1.00e+00	6.914	1	1	9
GO:0032479	regulation of type I interferon production	8.27e-03	1.00e+00	6.914	1	1	9
GO:0070062	extracellular vesicular exosome	9.25e-03	1.00e+00	1.725	5	28	1641
GO:0007067	mitotic nuclear division	9.45e-03	1.00e+00	3.717	2	5	165
GO:0042273	ribosomal large subunit biogenesis	1.01e-02	1.00e+00	6.624	1	1	11
GO:0033365	protein localization to organelle	1.01e-02	1.00e+00	6.624	1	1	11
GO:0016282	eukaryotic 43S preinitiation complex	1.01e-02	1.00e+00	6.624	1	1	11
GO:0033290	eukaryotic 48S preinitiation complex	1.01e-02	1.00e+00	6.624	1	1	11
GO:0031369	translation initiation factor binding	1.19e-02	1.00e+00	6.383	1	1	13
GO:0048821	erythrocyte development	1.19e-02	1.00e+00	6.383	1	2	13
GO:0005852	eukaryotic translation initiation factor 3 complex	1.19e-02	1.00e+00	6.383	1	1	13
GO:0017134	fibroblast growth factor binding	1.19e-02	1.00e+00	6.383	1	2	13
GO:0006259	DNA metabolic process	1.28e-02	1.00e+00	6.276	1	1	14
GO:0001731	formation of translation preinitiation complex	1.28e-02	1.00e+00	6.276	1	1	14
GO:0005978	glycogen biosynthetic process	1.37e-02	1.00e+00	6.177	1	1	15
GO:0043065	positive regulation of apoptotic process	1.39e-02	1.00e+00	3.425	2	3	202
GO:0007220	Notch receptor processing	1.47e-02	1.00e+00	6.083	1	1	16
GO:0000793	condensed chromosome	1.47e-02	1.00e+00	6.083	1	1	16
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	1.56e-02	1.00e+00	5.996	1	1	17
GO:0043021	ribonucleoprotein complex binding	1.56e-02	1.00e+00	5.996	1	1	17
GO:0007369	gastrulation	1.56e-02	1.00e+00	5.996	1	1	17
GO:0007052	mitotic spindle organization	1.56e-02	1.00e+00	5.996	1	1	17
GO:0006611	protein export from nucleus	1.65e-02	1.00e+00	5.914	1	1	18
GO:0005844	polysome	1.74e-02	1.00e+00	5.836	1	1	19
GO:0036464	cytoplasmic ribonucleoprotein granule	1.74e-02	1.00e+00	5.836	1	4	19
GO:0019901	protein kinase binding	1.81e-02	1.00e+00	3.225	2	8	232
GO:0045296	cadherin binding	1.83e-02	1.00e+00	5.762	1	1	20
GO:0032480	negative regulation of type I interferon production	1.83e-02	1.00e+00	5.762	1	1	20
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	2.01e-02	1.00e+00	5.624	1	1	22
GO:0007286	spermatid development	2.10e-02	1.00e+00	5.560	1	1	23
GO:0007093	mitotic cell cycle checkpoint	2.28e-02	1.00e+00	5.440	1	2	25
GO:0001890	placenta development	2.37e-02	1.00e+00	5.383	1	1	26
GO:0007249	I-kappaB kinase/NF-kappaB signaling	2.37e-02	1.00e+00	5.383	1	2	26
GO:0033077	T cell differentiation in thymus	2.37e-02	1.00e+00	5.383	1	1	26
GO:0034332	adherens junction organization	2.55e-02	1.00e+00	5.276	1	3	28
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	2.55e-02	1.00e+00	5.276	1	2	28
GO:0016197	endosomal transport	2.55e-02	1.00e+00	5.276	1	1	28
GO:0005925	focal adhesion	2.62e-02	1.00e+00	2.944	2	12	282
GO:0006446	regulation of translational initiation	2.64e-02	1.00e+00	5.225	1	2	29
GO:0050681	androgen receptor binding	2.73e-02	1.00e+00	5.177	1	2	30
GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	2.82e-02	1.00e+00	5.129	1	1	31
GO:0019003	GDP binding	3.09e-02	1.00e+00	4.996	1	1	34
GO:0032092	positive regulation of protein binding	3.09e-02	1.00e+00	4.996	1	1	34
GO:0007254	JNK cascade	3.09e-02	1.00e+00	4.996	1	1	34
GO:0030521	androgen receptor signaling pathway	3.18e-02	1.00e+00	4.954	1	3	35
GO:0044297	cell body	3.18e-02	1.00e+00	4.954	1	1	35
GO:0030666	endocytic vesicle membrane	3.27e-02	1.00e+00	4.914	1	1	36
GO:0043066	negative regulation of apoptotic process	3.35e-02	1.00e+00	2.753	2	6	322
GO:0003743	translation initiation factor activity	3.36e-02	1.00e+00	4.874	1	5	37
GO:0005515	protein binding	3.44e-02	1.00e+00	0.881	7	50	4124
GO:0051403	stress-activated MAPK cascade	3.81e-02	1.00e+00	4.691	1	2	42
GO:0045216	cell-cell junction organization	3.98e-02	1.00e+00	4.624	1	2	44
GO:0032481	positive regulation of type I interferon production	4.34e-02	1.00e+00	4.499	1	1	48
GO:0034146	toll-like receptor 5 signaling pathway	4.52e-02	1.00e+00	4.440	1	2	50
GO:0034166	toll-like receptor 10 signaling pathway	4.52e-02	1.00e+00	4.440	1	2	50
GO:0043197	dendritic spine	4.61e-02	1.00e+00	4.411	1	2	51
GO:0005643	nuclear pore	4.61e-02	1.00e+00	4.411	1	1	51
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.69e-02	1.00e+00	4.383	1	3	52
GO:0034329	cell junction assembly	4.78e-02	1.00e+00	4.356	1	2	53
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	4.78e-02	1.00e+00	4.356	1	1	53
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	4.78e-02	1.00e+00	4.356	1	3	53
GO:0038123	toll-like receptor TLR1:TLR2 signaling pathway	4.96e-02	1.00e+00	4.302	1	2	55
GO:0034162	toll-like receptor 9 signaling pathway	4.96e-02	1.00e+00	4.302	1	2	55
GO:0038124	toll-like receptor TLR6:TLR2 signaling pathway	4.96e-02	1.00e+00	4.302	1	2	55
GO:0034134	toll-like receptor 2 signaling pathway	5.05e-02	1.00e+00	4.276	1	2	56
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.05e-02	1.00e+00	4.276	1	3	56
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	5.13e-02	1.00e+00	4.251	1	3	57
GO:0003729	mRNA binding	5.13e-02	1.00e+00	4.251	1	1	57
GO:0035666	TRIF-dependent toll-like receptor signaling pathway	5.13e-02	1.00e+00	4.251	1	2	57
GO:0002756	MyD88-independent toll-like receptor signaling pathway	5.22e-02	1.00e+00	4.225	1	2	58
GO:0034138	toll-like receptor 3 signaling pathway	5.31e-02	1.00e+00	4.201	1	2	59
GO:0090090	negative regulation of canonical Wnt signaling pathway	5.31e-02	1.00e+00	4.201	1	3	59
GO:0000785	chromatin	5.31e-02	1.00e+00	4.201	1	2	59
GO:0042593	glucose homeostasis	5.40e-02	1.00e+00	4.177	1	1	60
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.40e-02	1.00e+00	4.177	1	3	60
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	5.49e-02	1.00e+00	4.153	1	2	61
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	5.49e-02	1.00e+00	4.153	1	3	61
GO:0016337	single organismal cell-cell adhesion	5.57e-02	1.00e+00	4.129	1	1	62
GO:0000187	activation of MAPK activity	5.66e-02	1.00e+00	4.106	1	2	63
GO:0042470	melanosome	5.75e-02	1.00e+00	4.083	1	2	64
GO:0030426	growth cone	5.75e-02	1.00e+00	4.083	1	3	64
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	5.84e-02	1.00e+00	4.061	1	3	65
GO:0050852	T cell receptor signaling pathway	6.10e-02	1.00e+00	3.996	1	1	68
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	6.27e-02	1.00e+00	3.954	1	4	70
GO:0030496	midbody	6.53e-02	1.00e+00	3.894	1	3	73
GO:0051726	regulation of cell cycle	6.53e-02	1.00e+00	3.894	1	1	73
GO:0034142	toll-like receptor 4 signaling pathway	6.53e-02	1.00e+00	3.894	1	2	73
GO:0071456	cellular response to hypoxia	6.79e-02	1.00e+00	3.836	1	1	76
GO:0006006	glucose metabolic process	7.14e-02	1.00e+00	3.762	1	2	80
GO:0030529	ribonucleoprotein complex	7.31e-02	1.00e+00	3.726	1	3	82
GO:0097190	apoptotic signaling pathway	7.40e-02	1.00e+00	3.708	1	1	83
GO:0045202	synapse	7.40e-02	1.00e+00	3.708	1	1	83
GO:0002224	toll-like receptor signaling pathway	7.40e-02	1.00e+00	3.708	1	2	83
GO:0016055	Wnt signaling pathway	7.74e-02	1.00e+00	3.641	1	2	87
GO:0030027	lamellipodium	7.83e-02	1.00e+00	3.624	1	3	88
GO:0051092	positive regulation of NF-kappaB transcription factor activity	7.91e-02	1.00e+00	3.608	1	1	89
GO:0061024	membrane organization	7.91e-02	1.00e+00	3.608	1	3	89
GO:0000209	protein polyubiquitination	8.17e-02	1.00e+00	3.560	1	3	92
GO:0007219	Notch signaling pathway	8.43e-02	1.00e+00	3.514	1	2	95
GO:0034220	ion transmembrane transport	8.51e-02	1.00e+00	3.499	1	1	96
GO:0000086	G2/M transition of mitotic cell cycle	8.60e-02	1.00e+00	3.484	1	3	97
GO:0008286	insulin receptor signaling pathway	8.60e-02	1.00e+00	3.484	1	2	97
GO:0010008	endosome membrane	9.02e-02	1.00e+00	3.411	1	1	102
GO:0005730	nucleolus	9.11e-02	1.00e+00	1.419	3	21	1217
GO:0005911	cell-cell junction	9.19e-02	1.00e+00	3.383	1	2	104
GO:0007179	transforming growth factor beta receptor signaling pathway	9.44e-02	1.00e+00	3.342	1	2	107
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	9.53e-02	1.00e+00	3.329	1	1	108
GO:0042981	regulation of apoptotic process	9.87e-02	1.00e+00	3.276	1	4	112
GO:0008543	fibroblast growth factor receptor signaling pathway	1.00e-01	1.00e+00	3.251	1	1	114
GO:0007420	brain development	1.05e-01	1.00e+00	3.189	1	2	119
GO:0003924	GTPase activity	1.05e-01	1.00e+00	3.189	1	3	119
GO:0006184	GTP catabolic process	1.14e-01	1.00e+00	3.061	1	3	130
GO:0019904	protein domain specific binding	1.14e-01	1.00e+00	3.061	1	1	130
GO:0038095	Fc-epsilon receptor signaling pathway	1.15e-01	1.00e+00	3.039	1	1	132
GO:0007173	epidermal growth factor receptor signaling pathway	1.24e-01	1.00e+00	2.934	1	3	142
GO:0006367	transcription initiation from RNA polymerase II promoter	1.39e-01	1.00e+00	2.753	1	3	161
GO:0030425	dendrite	1.43e-01	1.00e+00	2.708	1	3	166
GO:0019221	cytokine-mediated signaling pathway	1.48e-01	1.00e+00	2.657	1	4	172
GO:0007264	small GTPase mediated signal transduction	1.49e-01	1.00e+00	2.641	1	4	174
GO:0005102	receptor binding	1.49e-01	1.00e+00	2.641	1	1	174
GO:0003713	transcription coactivator activity	1.57e-01	1.00e+00	2.560	1	3	184
GO:0005975	carbohydrate metabolic process	1.59e-01	1.00e+00	2.544	1	1	186
GO:0005575	cellular_component	1.60e-01	1.00e+00	2.537	1	2	187
GO:0005525	GTP binding	1.68e-01	1.00e+00	2.461	1	3	197
GO:0048011	neurotrophin TRK receptor signaling pathway	1.69e-01	1.00e+00	2.447	1	2	199
GO:0006281	DNA repair	1.72e-01	1.00e+00	2.418	1	2	203
GO:0019899	enzyme binding	1.78e-01	1.00e+00	2.369	1	3	210
GO:0044281	small molecule metabolic process	1.79e-01	1.00e+00	1.362	2	8	844
GO:0008283	cell proliferation	2.00e-01	1.00e+00	2.183	1	1	239
GO:0005737	cytoplasm	2.04e-01	1.00e+00	0.721	4	39	2633
GO:0007155	cell adhesion	2.04e-01	1.00e+00	2.153	1	2	244
GO:0003723	RNA binding	2.06e-01	1.00e+00	2.135	1	6	247
GO:0003682	chromatin binding	2.10e-01	1.00e+00	2.106	1	3	252
GO:0008150	biological_process	2.23e-01	1.00e+00	2.007	1	2	270
GO:0000278	mitotic cell cycle	2.55e-01	1.00e+00	1.789	1	9	314
GO:0006351	transcription, DNA-templated	2.61e-01	1.00e+00	1.012	2	15	1076
GO:0055085	transmembrane transport	2.66e-01	1.00e+00	1.722	1	1	329
GO:0048471	perinuclear region of cytoplasm	2.76e-01	1.00e+00	1.657	1	7	344
GO:0045893	positive regulation of transcription, DNA-templated	2.98e-01	1.00e+00	1.525	1	6	377
GO:0006915	apoptotic process	3.21e-01	1.00e+00	1.400	1	4	411
GO:0045087	innate immune response	3.47e-01	1.00e+00	1.263	1	6	452
GO:0005634	nucleus	3.47e-01	1.00e+00	0.419	4	40	3246
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.50e-01	1.00e+00	1.251	1	6	456
GO:0007165	signal transduction	4.45e-01	1.00e+00	0.812	1	5	618
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	4.59e-01	1.00e+00	0.753	1	8	644
GO:0006355	regulation of transcription, DNA-templated	4.96e-01	1.00e+00	0.602	1	9	715
GO:0005886	plasma membrane	5.10e-01	1.00e+00	0.283	2	13	1784
GO:0046872	metal ion binding	5.96e-01	1.00e+00	0.216	1	10	934

Tai-Luciferase

reg-snw-1500

Statistics

Genes (9)

Interactions (8)

Related GO terms (189)