reg-snw-1121

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
tai-screen-luciferase	4.707	1.91e-24	5.19e-04	8.44e-04

tai-screen-luciferase-reg-snw-1121 subnetwork

Genes (5)

Gene Symbol	Entrez Gene ID	Frequency	tai-screen-luciferase gene score	Best subnetwork score	Degree	Transcription factor	List-Gonzales GI	Tai-Hits
RB1	5925	5	-2.085	4.707	351	TF	-	-
CDC42	998	5	-6.960	4.707	11	-	Yes	Yes
COPA	1314	25	-9.395	5.672	170	TF	Yes	Yes
[ CHM ]	1121	1	-0.483	4.707	2	-	-	-
SERBP1	26135	10	-4.612	5.516	43	-	-	Yes

Interactions (5)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CHM	1121	RB1	5925	pd	<	reg.ITFP.txt: no annot
COPA	1314	RB1	5925	pd	<>	reg.ITFP.txt: no annot
CHM	1121	COPA	1314	pd	<	reg.ITFP.txt: no annot
CDC42	998	RB1	5925	pd	<	reg.pazar.txt: no annot
RB1	5925	SERBP1	26135	pd	>	reg.pazar.txt: no annot

Related GO terms (172)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0090230	regulation of centromere complex assembly	5.12e-04	1.00e+00	10.931	1	1	1
GO:0031134	sister chromatid biorientation	5.12e-04	1.00e+00	10.931	1	1	1
GO:0035088	establishment or maintenance of apical/basal cell polarity	1.02e-03	1.00e+00	9.931	1	1	2
GO:0051683	establishment of Golgi localization	1.02e-03	1.00e+00	9.931	1	1	2
GO:0071338	positive regulation of hair follicle cell proliferation	1.02e-03	1.00e+00	9.931	1	1	2
GO:0051835	positive regulation of synapse structural plasticity	1.02e-03	1.00e+00	9.931	1	1	2
GO:0090135	actin filament branching	1.02e-03	1.00e+00	9.931	1	1	2
GO:0034088	maintenance of mitotic sister chromatid cohesion	1.02e-03	1.00e+00	9.931	1	1	2
GO:0072384	organelle transport along microtubule	1.02e-03	1.00e+00	9.931	1	1	2
GO:0060661	submandibular salivary gland formation	1.02e-03	1.00e+00	9.931	1	1	2
GO:0007070	negative regulation of transcription from RNA polymerase II promoter during mitosis	1.02e-03	1.00e+00	9.931	1	1	2
GO:0005968	Rab-protein geranylgeranyltransferase complex	1.54e-03	1.00e+00	9.347	1	1	3
GO:0060684	epithelial-mesenchymal cell signaling	1.54e-03	1.00e+00	9.347	1	1	3
GO:0003161	cardiac conduction system development	1.54e-03	1.00e+00	9.347	1	1	3
GO:0071459	protein localization to chromosome, centromeric region	1.54e-03	1.00e+00	9.347	1	1	3
GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle	1.54e-03	1.00e+00	9.347	1	1	3
GO:0030157	pancreatic juice secretion	2.05e-03	1.00e+00	8.931	1	1	4
GO:0071922	regulation of cohesin localization to chromatin	2.05e-03	1.00e+00	8.931	1	2	4
GO:0034191	apolipoprotein A-I receptor binding	2.05e-03	1.00e+00	8.931	1	1	4
GO:0090136	epithelial cell-cell adhesion	2.05e-03	1.00e+00	8.931	1	2	4
GO:0036336	dendritic cell migration	2.05e-03	1.00e+00	8.931	1	1	4
GO:0048664	neuron fate determination	2.05e-03	1.00e+00	8.931	1	1	4
GO:0043550	regulation of lipid kinase activity	2.05e-03	1.00e+00	8.931	1	1	4
GO:0031256	leading edge membrane	2.05e-03	1.00e+00	8.931	1	1	4
GO:0035189	Rb-E2F complex	2.05e-03	1.00e+00	8.931	1	1	4
GO:0034349	glial cell apoptotic process	2.05e-03	1.00e+00	8.931	1	1	4
GO:0048554	positive regulation of metalloenzyme activity	2.05e-03	1.00e+00	8.931	1	1	4
GO:0004663	Rab geranylgeranyltransferase activity	2.05e-03	1.00e+00	8.931	1	1	4
GO:0018344	protein geranylgeranylation	2.56e-03	1.00e+00	8.610	1	1	5
GO:0007097	nuclear migration	2.56e-03	1.00e+00	8.610	1	2	5
GO:0031274	positive regulation of pseudopodium assembly	2.56e-03	1.00e+00	8.610	1	1	5
GO:0003334	keratinocyte development	2.56e-03	1.00e+00	8.610	1	1	5
GO:0048667	cell morphogenesis involved in neuron differentiation	2.56e-03	1.00e+00	8.610	1	1	5
GO:0045842	positive regulation of mitotic metaphase/anaphase transition	2.56e-03	1.00e+00	8.610	1	1	5
GO:0060789	hair follicle placode formation	3.07e-03	1.00e+00	8.347	1	1	6
GO:0043353	enucleate erythrocyte differentiation	3.07e-03	1.00e+00	8.347	1	1	6
GO:0000075	cell cycle checkpoint	3.07e-03	1.00e+00	8.347	1	1	6
GO:0051489	regulation of filopodium assembly	3.07e-03	1.00e+00	8.347	1	1	6
GO:0060047	heart contraction	3.07e-03	1.00e+00	8.347	1	1	6
GO:0043497	regulation of protein heterodimerization activity	3.07e-03	1.00e+00	8.347	1	1	6
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	3.58e-03	1.00e+00	8.124	1	1	7
GO:0030126	COPI vesicle coat	3.58e-03	1.00e+00	8.124	1	1	7
GO:0051233	spindle midzone	4.09e-03	1.00e+00	7.931	1	1	8
GO:0097284	hepatocyte apoptotic process	4.60e-03	1.00e+00	7.762	1	1	9
GO:0031996	thioesterase binding	4.60e-03	1.00e+00	7.762	1	1	9
GO:0042551	neuron maturation	5.11e-03	1.00e+00	7.610	1	1	10
GO:0045651	positive regulation of macrophage differentiation	5.11e-03	1.00e+00	7.610	1	1	10
GO:0043488	regulation of mRNA stability	5.11e-03	1.00e+00	7.610	1	1	10
GO:0031333	negative regulation of protein complex assembly	5.62e-03	1.00e+00	7.472	1	1	11
GO:0030742	GTP-dependent protein binding	5.62e-03	1.00e+00	7.472	1	1	11
GO:0006612	protein targeting to membrane	5.62e-03	1.00e+00	7.472	1	1	11
GO:0090316	positive regulation of intracellular protein transport	5.62e-03	1.00e+00	7.472	1	1	11
GO:0030225	macrophage differentiation	5.62e-03	1.00e+00	7.472	1	1	11
GO:0007088	regulation of mitosis	6.13e-03	1.00e+00	7.347	1	1	12
GO:0048205	COPI coating of Golgi vesicle	6.13e-03	1.00e+00	7.347	1	1	12
GO:0051146	striated muscle cell differentiation	6.13e-03	1.00e+00	7.347	1	2	12
GO:0045445	myoblast differentiation	6.64e-03	1.00e+00	7.231	1	1	13
GO:0016514	SWI/SNF complex	6.64e-03	1.00e+00	7.231	1	1	13
GO:0046847	filopodium assembly	7.15e-03	1.00e+00	7.124	1	1	14
GO:0042176	regulation of protein catabolic process	7.15e-03	1.00e+00	7.124	1	3	14
GO:0045859	regulation of protein kinase activity	7.15e-03	1.00e+00	7.124	1	1	14
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	7.66e-03	1.00e+00	7.025	1	1	15
GO:0045879	negative regulation of smoothened signaling pathway	7.66e-03	1.00e+00	7.025	1	1	15
GO:0051017	actin filament bundle assembly	7.66e-03	1.00e+00	7.025	1	1	15
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	8.17e-03	1.00e+00	6.931	1	1	16
GO:0032467	positive regulation of cytokinesis	8.17e-03	1.00e+00	6.931	1	1	16
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	8.68e-03	1.00e+00	6.844	1	1	17
GO:0031435	mitogen-activated protein kinase kinase kinase binding	9.18e-03	1.00e+00	6.762	1	1	18
GO:0031069	hair follicle morphogenesis	9.18e-03	1.00e+00	6.762	1	1	18
GO:0048565	digestive tract development	9.69e-03	1.00e+00	6.684	1	1	19
GO:0036464	cytoplasmic ribonucleoprotein granule	9.69e-03	1.00e+00	6.684	1	4	19
GO:0007163	establishment or maintenance of cell polarity	1.02e-02	1.00e+00	6.610	1	2	20
GO:0072686	mitotic spindle	1.02e-02	1.00e+00	6.610	1	1	20
GO:0007346	regulation of mitotic cell cycle	1.07e-02	1.00e+00	6.539	1	1	21
GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	1.07e-02	1.00e+00	6.539	1	1	21
GO:0031647	regulation of protein stability	1.07e-02	1.00e+00	6.539	1	1	21
GO:0051149	positive regulation of muscle cell differentiation	1.12e-02	1.00e+00	6.472	1	2	22
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	1.12e-02	1.00e+00	6.472	1	1	22
GO:0002040	sprouting angiogenesis	1.12e-02	1.00e+00	6.472	1	1	22
GO:0031424	keratinization	1.17e-02	1.00e+00	6.408	1	1	23
GO:0042802	identical protein binding	1.22e-02	1.00e+00	3.464	2	2	354
GO:0007030	Golgi organization	1.27e-02	1.00e+00	6.288	1	2	25
GO:0007093	mitotic cell cycle checkpoint	1.27e-02	1.00e+00	6.288	1	2	25
GO:0003730	mRNA 3'-UTR binding	1.27e-02	1.00e+00	6.288	1	1	25
GO:0051219	phosphoprotein binding	1.27e-02	1.00e+00	6.288	1	3	25
GO:0034613	cellular protein localization	1.32e-02	1.00e+00	6.231	1	2	26
GO:0050896	response to stimulus	1.38e-02	1.00e+00	6.177	1	1	27
GO:0034332	adherens junction organization	1.43e-02	1.00e+00	6.124	1	3	28
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	1.43e-02	1.00e+00	6.124	1	2	28
GO:0042692	muscle cell differentiation	1.43e-02	1.00e+00	6.124	1	2	28
GO:0051402	neuron apoptotic process	1.53e-02	1.00e+00	6.025	1	1	30
GO:0050681	androgen receptor binding	1.53e-02	1.00e+00	6.025	1	2	30
GO:0016020	membrane	1.55e-02	1.00e+00	2.279	3	25	1207
GO:0001102	RNA polymerase II activating transcription factor binding	1.58e-02	1.00e+00	5.977	1	1	31
GO:0001568	blood vessel development	1.58e-02	1.00e+00	5.977	1	1	31
GO:0045740	positive regulation of DNA replication	1.63e-02	1.00e+00	5.931	1	1	32
GO:0019900	kinase binding	1.63e-02	1.00e+00	5.931	1	2	32
GO:0035914	skeletal muscle cell differentiation	1.68e-02	1.00e+00	5.887	1	1	33
GO:0021762	substantia nigra development	1.73e-02	1.00e+00	5.844	1	2	34
GO:0046330	positive regulation of JNK cascade	1.73e-02	1.00e+00	5.844	1	1	34
GO:0030521	androgen receptor signaling pathway	1.78e-02	1.00e+00	5.802	1	3	35
GO:0030175	filopodium	1.88e-02	1.00e+00	5.722	1	2	37
GO:0050680	negative regulation of epithelial cell proliferation	1.98e-02	1.00e+00	5.646	1	1	39
GO:0043525	positive regulation of neuron apoptotic process	2.08e-02	1.00e+00	5.574	1	2	41
GO:0001047	core promoter binding	2.13e-02	1.00e+00	5.539	1	1	42
GO:0017137	Rab GTPase binding	2.18e-02	1.00e+00	5.505	1	1	43
GO:0030141	secretory granule	2.23e-02	1.00e+00	5.472	1	2	44
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	2.28e-02	1.00e+00	5.440	1	1	45
GO:0033138	positive regulation of peptidyl-serine phosphorylation	2.43e-02	1.00e+00	5.347	1	1	48
GO:0006469	negative regulation of protein kinase activity	2.53e-02	1.00e+00	5.288	1	1	50
GO:0060070	canonical Wnt signaling pathway	2.58e-02	1.00e+00	5.259	1	2	51
GO:0031295	T cell costimulation	2.58e-02	1.00e+00	5.259	1	1	51
GO:0045177	apical part of cell	2.74e-02	1.00e+00	5.177	1	1	54
GO:0035264	multicellular organism growth	2.74e-02	1.00e+00	5.177	1	1	54
GO:0006338	chromatin remodeling	2.79e-02	1.00e+00	5.150	1	2	55
GO:0031175	neuron projection development	2.79e-02	1.00e+00	5.150	1	2	55
GO:0000785	chromatin	2.99e-02	1.00e+00	5.049	1	2	59
GO:0007265	Ras protein signal transduction	2.99e-02	1.00e+00	5.049	1	2	59
GO:0005179	hormone activity	3.04e-02	1.00e+00	5.025	1	1	60
GO:0010629	negative regulation of gene expression	3.14e-02	1.00e+00	4.977	1	2	62
GO:0005096	GTPase activator activity	3.43e-02	1.00e+00	4.844	1	3	68
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	3.53e-02	1.00e+00	4.802	1	3	70
GO:0070062	extracellular vesicular exosome	3.63e-02	1.00e+00	1.836	3	28	1641
GO:0030496	midbody	3.68e-02	1.00e+00	4.742	1	3	73
GO:0051056	regulation of small GTPase mediated signal transduction	3.83e-02	1.00e+00	4.684	1	1	76
GO:0005815	microtubule organizing center	3.88e-02	1.00e+00	4.665	1	2	77
GO:0016605	PML body	3.98e-02	1.00e+00	4.628	1	1	79
GO:0005819	spindle	4.03e-02	1.00e+00	4.610	1	2	80
GO:0061024	membrane organization	4.48e-02	1.00e+00	4.456	1	3	89
GO:0006886	intracellular protein transport	4.48e-02	1.00e+00	4.456	1	1	89
GO:0030036	actin cytoskeleton organization	4.53e-02	1.00e+00	4.440	1	2	90
GO:0005829	cytosol	4.57e-02	1.00e+00	1.713	3	33	1787
GO:0007050	cell cycle arrest	4.62e-02	1.00e+00	4.408	1	2	92
GO:0007601	visual perception	4.87e-02	1.00e+00	4.332	1	1	97
GO:0005198	structural molecule activity	5.07e-02	1.00e+00	4.273	1	1	101
GO:0005911	cell-cell junction	5.21e-02	1.00e+00	4.231	1	2	104
GO:0010628	positive regulation of gene expression	5.31e-02	1.00e+00	4.204	1	2	106
GO:0043547	positive regulation of GTPase activity	5.61e-02	1.00e+00	4.124	1	4	112
GO:0042981	regulation of apoptotic process	5.61e-02	1.00e+00	4.124	1	4	112
GO:0043005	neuron projection	5.65e-02	1.00e+00	4.111	1	2	113
GO:0003924	GTPase activity	5.95e-02	1.00e+00	4.037	1	3	119
GO:0000082	G1/S transition of mitotic cell cycle	6.24e-02	1.00e+00	3.966	1	6	125
GO:0006184	GTP catabolic process	6.48e-02	1.00e+00	3.909	1	3	130
GO:0031625	ubiquitin protein ligase binding	6.87e-02	1.00e+00	3.823	1	2	138
GO:0007173	epidermal growth factor receptor signaling pathway	7.06e-02	1.00e+00	3.782	1	3	142
GO:0043025	neuronal cell body	8.46e-02	1.00e+00	3.514	1	3	171
GO:0007264	small GTPase mediated signal transduction	8.60e-02	1.00e+00	3.489	1	4	174
GO:0003713	transcription coactivator activity	9.07e-02	1.00e+00	3.408	1	3	184
GO:0005525	GTP binding	9.69e-02	1.00e+00	3.309	1	3	197
GO:0008134	transcription factor binding	1.03e-01	1.00e+00	3.224	1	5	209
GO:0019901	protein kinase binding	1.13e-01	1.00e+00	3.073	1	8	232
GO:0007411	axon guidance	1.16e-01	1.00e+00	3.043	1	2	237
GO:0005737	cytoplasm	1.25e-01	1.00e+00	1.154	3	39	2633
GO:0000139	Golgi membrane	1.29e-01	1.00e+00	2.871	1	4	267
GO:0005925	focal adhesion	1.36e-01	1.00e+00	2.792	1	12	282
GO:0000278	mitotic cell cycle	1.51e-01	1.00e+00	2.637	1	9	314
GO:0045892	negative regulation of transcription, DNA-templated	1.52e-01	1.00e+00	2.623	1	1	317
GO:0007596	blood coagulation	1.62e-01	1.00e+00	2.526	1	4	339
GO:0048471	perinuclear region of cytoplasm	1.64e-01	1.00e+00	2.505	1	7	344
GO:0045893	positive regulation of transcription, DNA-templated	1.79e-01	1.00e+00	2.373	1	6	377
GO:0016032	viral process	2.01e-01	1.00e+00	2.190	1	13	428
GO:0045087	innate immune response	2.11e-01	1.00e+00	2.111	1	6	452
GO:0005886	plasma membrane	2.28e-01	1.00e+00	1.131	2	13	1784
GO:0003700	sequence-specific DNA binding transcription factor activity	2.65e-01	1.00e+00	1.747	1	9	582
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	2.89e-01	1.00e+00	1.601	1	8	644
GO:0005615	extracellular space	2.92e-01	1.00e+00	1.585	1	2	651
GO:0044822	poly(A) RNA binding	3.47e-01	1.00e+00	1.289	1	25	799
GO:0005515	protein binding	3.57e-01	1.00e+00	0.507	3	50	4124
GO:0005654	nucleoplasm	3.75e-01	1.00e+00	1.157	1	16	876
GO:0003677	DNA binding	4.00e-01	1.00e+00	1.044	1	12	947
GO:0006351	transcription, DNA-templated	4.42e-01	1.00e+00	0.860	1	15	1076
GO:0005634	nucleus	5.37e-01	1.00e+00	0.267	2	40	3246

Tai-Luciferase

reg-snw-1121

Statistics

Genes (5)

Interactions (5)

Related GO terms (172)