reg-snw-51164

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
tai-screen-luciferase	4.586	4.41e-23	8.78e-04	1.37e-03

tai-screen-luciferase-reg-snw-51164 subnetwork

Genes (6)

Gene Symbol	Entrez Gene ID	Frequency	tai-screen-luciferase gene score	Best subnetwork score	Degree	Transcription factor	List-Gonzales GI	Tai-Hits
RB1	5925	5	-2.085	4.707	351	TF	-	-
COPA	1314	25	-9.395	5.672	170	TF	Yes	Yes
CDC42	998	5	-6.960	4.707	11	-	Yes	Yes
PAFAH1B1	5048	3	-2.583	4.586	55	TF	Yes	-
SERBP1	26135	10	-4.612	5.516	43	-	-	Yes
[ DCTN4 ]	51164	1	-1.882	4.586	19	-	-	-

Interactions (7)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CDC42	998	RB1	5925	pd	<	reg.pazar.txt: no annot
COPA	1314	DCTN4	51164	pd	>	reg.ITFP.txt: no annot
COPA	1314	RB1	5925	pd	<>	reg.ITFP.txt: no annot
PAFAH1B1	5048	DCTN4	51164	pd	>	reg.ITFP.txt: no annot
COPA	1314	PAFAH1B1	5048	pd	<>	reg.ITFP.txt: no annot
RB1	5925	SERBP1	26135	pd	>	reg.pazar.txt: no annot
RB1	5925	DCTN4	51164	pd	>	reg.ITFP.txt: no annot

Related GO terms (220)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0007097	nuclear migration	3.14e-06	3.07e-02	9.347	2	2	5
GO:0051219	phosphoprotein binding	9.38e-05	9.16e-01	7.025	2	3	25
GO:0051081	nuclear envelope disassembly	6.14e-04	1.00e+00	10.668	1	1	1
GO:0090230	regulation of centromere complex assembly	6.14e-04	1.00e+00	10.668	1	1	1
GO:0000235	astral microtubule	6.14e-04	1.00e+00	10.668	1	1	1
GO:0051660	establishment of centrosome localization	6.14e-04	1.00e+00	10.668	1	1	1
GO:0031134	sister chromatid biorientation	6.14e-04	1.00e+00	10.668	1	1	1
GO:0036035	osteoclast development	6.14e-04	1.00e+00	10.668	1	1	1
GO:0046469	platelet activating factor metabolic process	6.14e-04	1.00e+00	10.668	1	1	1
GO:0035088	establishment or maintenance of apical/basal cell polarity	1.23e-03	1.00e+00	9.668	1	1	2
GO:0030036	actin cytoskeleton organization	1.23e-03	1.00e+00	5.177	2	2	90
GO:0051683	establishment of Golgi localization	1.23e-03	1.00e+00	9.668	1	1	2
GO:0071338	positive regulation of hair follicle cell proliferation	1.23e-03	1.00e+00	9.668	1	1	2
GO:0051835	positive regulation of synapse structural plasticity	1.23e-03	1.00e+00	9.668	1	1	2
GO:0090135	actin filament branching	1.23e-03	1.00e+00	9.668	1	1	2
GO:0034088	maintenance of mitotic sister chromatid cohesion	1.23e-03	1.00e+00	9.668	1	1	2
GO:0072384	organelle transport along microtubule	1.23e-03	1.00e+00	9.668	1	1	2
GO:0060661	submandibular salivary gland formation	1.23e-03	1.00e+00	9.668	1	1	2
GO:0045505	dynein intermediate chain binding	1.23e-03	1.00e+00	9.668	1	1	2
GO:0007070	negative regulation of transcription from RNA polymerase II promoter during mitosis	1.23e-03	1.00e+00	9.668	1	1	2
GO:0060684	epithelial-mesenchymal cell signaling	1.84e-03	1.00e+00	9.083	1	1	3
GO:0003161	cardiac conduction system development	1.84e-03	1.00e+00	9.083	1	1	3
GO:0071459	protein localization to chromosome, centromeric region	1.84e-03	1.00e+00	9.083	1	1	3
GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle	1.84e-03	1.00e+00	9.083	1	1	3
GO:0021540	corpus callosum morphogenesis	1.84e-03	1.00e+00	9.083	1	1	3
GO:0008090	retrograde axon cargo transport	2.46e-03	1.00e+00	8.668	1	1	4
GO:0030157	pancreatic juice secretion	2.46e-03	1.00e+00	8.668	1	1	4
GO:0071922	regulation of cohesin localization to chromatin	2.46e-03	1.00e+00	8.668	1	2	4
GO:0034191	apolipoprotein A-I receptor binding	2.46e-03	1.00e+00	8.668	1	1	4
GO:0090136	epithelial cell-cell adhesion	2.46e-03	1.00e+00	8.668	1	2	4
GO:0036336	dendritic cell migration	2.46e-03	1.00e+00	8.668	1	1	4
GO:0048664	neuron fate determination	2.46e-03	1.00e+00	8.668	1	1	4
GO:0043550	regulation of lipid kinase activity	2.46e-03	1.00e+00	8.668	1	1	4
GO:0031256	leading edge membrane	2.46e-03	1.00e+00	8.668	1	1	4
GO:0035189	Rb-E2F complex	2.46e-03	1.00e+00	8.668	1	1	4
GO:0034349	glial cell apoptotic process	2.46e-03	1.00e+00	8.668	1	1	4
GO:0001667	ameboidal-type cell migration	2.46e-03	1.00e+00	8.668	1	1	4
GO:0048554	positive regulation of metalloenzyme activity	2.46e-03	1.00e+00	8.668	1	1	4
GO:0031512	motile primary cilium	3.07e-03	1.00e+00	8.347	1	1	5
GO:0031274	positive regulation of pseudopodium assembly	3.07e-03	1.00e+00	8.347	1	1	5
GO:0003334	keratinocyte development	3.07e-03	1.00e+00	8.347	1	1	5
GO:0048667	cell morphogenesis involved in neuron differentiation	3.07e-03	1.00e+00	8.347	1	1	5
GO:0045842	positive regulation of mitotic metaphase/anaphase transition	3.07e-03	1.00e+00	8.347	1	1	5
GO:0034452	dynactin binding	3.07e-03	1.00e+00	8.347	1	1	5
GO:0031023	microtubule organizing center organization	3.07e-03	1.00e+00	8.347	1	1	5
GO:0060789	hair follicle placode formation	3.68e-03	1.00e+00	8.083	1	1	6
GO:0043353	enucleate erythrocyte differentiation	3.68e-03	1.00e+00	8.083	1	1	6
GO:0001961	positive regulation of cytokine-mediated signaling pathway	3.68e-03	1.00e+00	8.083	1	1	6
GO:0017145	stem cell division	3.68e-03	1.00e+00	8.083	1	1	6
GO:0000075	cell cycle checkpoint	3.68e-03	1.00e+00	8.083	1	1	6
GO:0005869	dynactin complex	3.68e-03	1.00e+00	8.083	1	1	6
GO:0051489	regulation of filopodium assembly	3.68e-03	1.00e+00	8.083	1	1	6
GO:0060047	heart contraction	3.68e-03	1.00e+00	8.083	1	1	6
GO:0043497	regulation of protein heterodimerization activity	3.68e-03	1.00e+00	8.083	1	1	6
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	4.29e-03	1.00e+00	7.861	1	1	7
GO:0001675	acrosome assembly	4.29e-03	1.00e+00	7.861	1	1	7
GO:0032319	regulation of Rho GTPase activity	4.29e-03	1.00e+00	7.861	1	1	7
GO:0030126	COPI vesicle coat	4.29e-03	1.00e+00	7.861	1	1	7
GO:0021895	cerebral cortex neuron differentiation	4.29e-03	1.00e+00	7.861	1	1	7
GO:0043025	neuronal cell body	4.37e-03	1.00e+00	4.251	2	3	171
GO:0045502	dynein binding	4.91e-03	1.00e+00	7.668	1	1	8
GO:0051233	spindle midzone	4.91e-03	1.00e+00	7.668	1	1	8
GO:0097284	hepatocyte apoptotic process	5.52e-03	1.00e+00	7.499	1	1	9
GO:0031996	thioesterase binding	5.52e-03	1.00e+00	7.499	1	1	9
GO:0048854	brain morphogenesis	5.52e-03	1.00e+00	7.499	1	1	9
GO:0042551	neuron maturation	6.13e-03	1.00e+00	7.347	1	1	10
GO:0045651	positive regulation of macrophage differentiation	6.13e-03	1.00e+00	7.347	1	1	10
GO:0043488	regulation of mRNA stability	6.13e-03	1.00e+00	7.347	1	1	10
GO:0009306	protein secretion	6.74e-03	1.00e+00	7.209	1	2	11
GO:0031333	negative regulation of protein complex assembly	6.74e-03	1.00e+00	7.209	1	1	11
GO:0045773	positive regulation of axon extension	6.74e-03	1.00e+00	7.209	1	1	11
GO:0030742	GTP-dependent protein binding	6.74e-03	1.00e+00	7.209	1	1	11
GO:0090316	positive regulation of intracellular protein transport	6.74e-03	1.00e+00	7.209	1	1	11
GO:0030225	macrophage differentiation	6.74e-03	1.00e+00	7.209	1	1	11
GO:0021819	layer formation in cerebral cortex	6.74e-03	1.00e+00	7.209	1	1	11
GO:0047496	vesicle transport along microtubule	6.74e-03	1.00e+00	7.209	1	1	11
GO:0005813	centrosome	6.95e-03	1.00e+00	3.907	2	6	217
GO:0007088	regulation of mitosis	7.35e-03	1.00e+00	7.083	1	1	12
GO:0043274	phospholipase binding	7.35e-03	1.00e+00	7.083	1	1	12
GO:0048205	COPI coating of Golgi vesicle	7.35e-03	1.00e+00	7.083	1	1	12
GO:0000132	establishment of mitotic spindle orientation	7.35e-03	1.00e+00	7.083	1	2	12
GO:0051146	striated muscle cell differentiation	7.35e-03	1.00e+00	7.083	1	2	12
GO:0045445	myoblast differentiation	7.96e-03	1.00e+00	6.968	1	1	13
GO:0016514	SWI/SNF complex	7.96e-03	1.00e+00	6.968	1	1	13
GO:0019226	transmission of nerve impulse	7.96e-03	1.00e+00	6.968	1	1	13
GO:0046847	filopodium assembly	8.57e-03	1.00e+00	6.861	1	1	14
GO:0007405	neuroblast proliferation	8.57e-03	1.00e+00	6.861	1	1	14
GO:0042176	regulation of protein catabolic process	8.57e-03	1.00e+00	6.861	1	3	14
GO:0045859	regulation of protein kinase activity	8.57e-03	1.00e+00	6.861	1	1	14
GO:0070062	extracellular vesicular exosome	8.95e-03	1.00e+00	1.988	4	28	1641
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	9.18e-03	1.00e+00	6.762	1	1	15
GO:0045879	negative regulation of smoothened signaling pathway	9.18e-03	1.00e+00	6.762	1	1	15
GO:0051017	actin filament bundle assembly	9.18e-03	1.00e+00	6.762	1	1	15
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	9.79e-03	1.00e+00	6.668	1	1	16
GO:0032467	positive regulation of cytokinesis	9.79e-03	1.00e+00	6.668	1	1	16
GO:0007017	microtubule-based process	1.04e-02	1.00e+00	6.581	1	1	17
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	1.04e-02	1.00e+00	6.581	1	1	17
GO:0031435	mitogen-activated protein kinase kinase kinase binding	1.10e-02	1.00e+00	6.499	1	1	18
GO:0031069	hair follicle morphogenesis	1.10e-02	1.00e+00	6.499	1	1	18
GO:0046329	negative regulation of JNK cascade	1.16e-02	1.00e+00	6.421	1	1	19
GO:0048565	digestive tract development	1.16e-02	1.00e+00	6.421	1	1	19
GO:0036464	cytoplasmic ribonucleoprotein granule	1.16e-02	1.00e+00	6.421	1	4	19
GO:0007163	establishment or maintenance of cell polarity	1.22e-02	1.00e+00	6.347	1	2	20
GO:0005829	cytosol	1.22e-02	1.00e+00	1.865	4	33	1787
GO:0072686	mitotic spindle	1.22e-02	1.00e+00	6.347	1	1	20
GO:0007346	regulation of mitotic cell cycle	1.28e-02	1.00e+00	6.276	1	1	21
GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	1.28e-02	1.00e+00	6.276	1	1	21
GO:0010977	negative regulation of neuron projection development	1.28e-02	1.00e+00	6.276	1	1	21
GO:0031647	regulation of protein stability	1.28e-02	1.00e+00	6.276	1	1	21
GO:0051149	positive regulation of muscle cell differentiation	1.34e-02	1.00e+00	6.209	1	2	22
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	1.34e-02	1.00e+00	6.209	1	1	22
GO:0002040	sprouting angiogenesis	1.34e-02	1.00e+00	6.209	1	1	22
GO:0005875	microtubule associated complex	1.34e-02	1.00e+00	6.209	1	1	22
GO:0031424	keratinization	1.41e-02	1.00e+00	6.145	1	1	23
GO:0045931	positive regulation of mitotic cell cycle	1.41e-02	1.00e+00	6.145	1	2	23
GO:0000278	mitotic cell cycle	1.42e-02	1.00e+00	3.374	2	9	314
GO:0031252	cell leading edge	1.47e-02	1.00e+00	6.083	1	2	24
GO:0007611	learning or memory	1.47e-02	1.00e+00	6.083	1	1	24
GO:0007030	Golgi organization	1.53e-02	1.00e+00	6.025	1	2	25
GO:0007093	mitotic cell cycle checkpoint	1.53e-02	1.00e+00	6.025	1	2	25
GO:0003730	mRNA 3'-UTR binding	1.53e-02	1.00e+00	6.025	1	1	25
GO:0034613	cellular protein localization	1.59e-02	1.00e+00	5.968	1	2	26
GO:0016042	lipid catabolic process	1.59e-02	1.00e+00	5.968	1	1	26
GO:0048471	perinuclear region of cytoplasm	1.69e-02	1.00e+00	3.242	2	7	344
GO:0034332	adherens junction organization	1.71e-02	1.00e+00	5.861	1	3	28
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	1.71e-02	1.00e+00	5.861	1	2	28
GO:0050885	neuromuscular process controlling balance	1.71e-02	1.00e+00	5.861	1	1	28
GO:0042692	muscle cell differentiation	1.71e-02	1.00e+00	5.861	1	2	28
GO:0042802	identical protein binding	1.78e-02	1.00e+00	3.201	2	2	354
GO:0021987	cerebral cortex development	1.83e-02	1.00e+00	5.762	1	1	30
GO:0051402	neuron apoptotic process	1.83e-02	1.00e+00	5.762	1	1	30
GO:0050681	androgen receptor binding	1.83e-02	1.00e+00	5.762	1	2	30
GO:0021766	hippocampus development	1.89e-02	1.00e+00	5.714	1	3	31
GO:0001102	RNA polymerase II activating transcription factor binding	1.89e-02	1.00e+00	5.714	1	1	31
GO:0005871	kinesin complex	1.89e-02	1.00e+00	5.714	1	1	31
GO:0045740	positive regulation of DNA replication	1.95e-02	1.00e+00	5.668	1	1	32
GO:0019900	kinase binding	1.95e-02	1.00e+00	5.668	1	2	32
GO:0008344	adult locomotory behavior	2.01e-02	1.00e+00	5.624	1	1	33
GO:0035914	skeletal muscle cell differentiation	2.01e-02	1.00e+00	5.624	1	1	33
GO:0021762	substantia nigra development	2.07e-02	1.00e+00	5.581	1	2	34
GO:0046330	positive regulation of JNK cascade	2.07e-02	1.00e+00	5.581	1	1	34
GO:0030521	androgen receptor signaling pathway	2.13e-02	1.00e+00	5.539	1	3	35
GO:0000226	microtubule cytoskeleton organization	2.19e-02	1.00e+00	5.499	1	1	36
GO:0030175	filopodium	2.25e-02	1.00e+00	5.459	1	2	37
GO:0050680	negative regulation of epithelial cell proliferation	2.37e-02	1.00e+00	5.383	1	1	39
GO:0043525	positive regulation of neuron apoptotic process	2.49e-02	1.00e+00	5.311	1	2	41
GO:0001047	core promoter binding	2.55e-02	1.00e+00	5.276	1	1	42
GO:0030141	secretory granule	2.67e-02	1.00e+00	5.209	1	2	44
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	2.73e-02	1.00e+00	5.177	1	1	45
GO:0016020	membrane	2.82e-02	1.00e+00	2.016	3	25	1207
GO:0033138	positive regulation of peptidyl-serine phosphorylation	2.91e-02	1.00e+00	5.083	1	1	48
GO:0006469	negative regulation of protein kinase activity	3.03e-02	1.00e+00	5.025	1	1	50
GO:0060070	canonical Wnt signaling pathway	3.09e-02	1.00e+00	4.996	1	2	51
GO:0031295	T cell costimulation	3.09e-02	1.00e+00	4.996	1	1	51
GO:0045177	apical part of cell	3.27e-02	1.00e+00	4.914	1	1	54
GO:0035264	multicellular organism growth	3.27e-02	1.00e+00	4.914	1	1	54
GO:0000776	kinetochore	3.33e-02	1.00e+00	4.887	1	1	55
GO:0006338	chromatin remodeling	3.33e-02	1.00e+00	4.887	1	2	55
GO:0031175	neuron projection development	3.33e-02	1.00e+00	4.887	1	2	55
GO:0000785	chromatin	3.57e-02	1.00e+00	4.786	1	2	59
GO:0007265	Ras protein signal transduction	3.57e-02	1.00e+00	4.786	1	2	59
GO:0005179	hormone activity	3.63e-02	1.00e+00	4.762	1	1	60
GO:0010629	negative regulation of gene expression	3.75e-02	1.00e+00	4.714	1	2	62
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	3.87e-02	1.00e+00	4.668	1	3	64
GO:0030426	growth cone	3.87e-02	1.00e+00	4.668	1	3	64
GO:0047485	protein N-terminus binding	3.93e-02	1.00e+00	4.646	1	1	65
GO:0001764	neuron migration	4.05e-02	1.00e+00	4.602	1	2	67
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	4.23e-02	1.00e+00	4.539	1	3	70
GO:0030496	midbody	4.40e-02	1.00e+00	4.479	1	3	73
GO:0051056	regulation of small GTPase mediated signal transduction	4.58e-02	1.00e+00	4.421	1	1	76
GO:0005938	cell cortex	4.64e-02	1.00e+00	4.402	1	1	77
GO:0005815	microtubule organizing center	4.64e-02	1.00e+00	4.402	1	2	77
GO:0016605	PML body	4.76e-02	1.00e+00	4.365	1	1	79
GO:0005819	spindle	4.82e-02	1.00e+00	4.347	1	2	80
GO:0005737	cytoplasm	4.89e-02	1.00e+00	1.306	4	39	2633
GO:0005635	nuclear envelope	4.99e-02	1.00e+00	4.293	1	2	83
GO:0061024	membrane organization	5.35e-02	1.00e+00	4.193	1	3	89
GO:0006886	intracellular protein transport	5.35e-02	1.00e+00	4.193	1	1	89
GO:0008201	heparin binding	5.46e-02	1.00e+00	4.161	1	1	91
GO:0007050	cell cycle arrest	5.52e-02	1.00e+00	4.145	1	2	92
GO:0000086	G2/M transition of mitotic cell cycle	5.82e-02	1.00e+00	4.069	1	3	97
GO:0008017	microtubule binding	5.82e-02	1.00e+00	4.069	1	1	97
GO:0005198	structural molecule activity	6.05e-02	1.00e+00	4.010	1	1	101
GO:0005911	cell-cell junction	6.22e-02	1.00e+00	3.968	1	2	104
GO:0010628	positive regulation of gene expression	6.34e-02	1.00e+00	3.941	1	2	106
GO:0042981	regulation of apoptotic process	6.69e-02	1.00e+00	3.861	1	4	112
GO:0043005	neuron projection	6.75e-02	1.00e+00	3.848	1	2	113
GO:0003924	GTPase activity	7.09e-02	1.00e+00	3.774	1	3	119
GO:0000082	G1/S transition of mitotic cell cycle	7.44e-02	1.00e+00	3.703	1	6	125
GO:0030424	axon	7.61e-02	1.00e+00	3.668	1	4	128
GO:0031965	nuclear membrane	7.73e-02	1.00e+00	3.646	1	2	130
GO:0006184	GTP catabolic process	7.73e-02	1.00e+00	3.646	1	3	130
GO:0031625	ubiquitin protein ligase binding	8.19e-02	1.00e+00	3.560	1	2	138
GO:0007173	epidermal growth factor receptor signaling pathway	8.42e-02	1.00e+00	3.519	1	3	142
GO:0007067	mitotic nuclear division	9.72e-02	1.00e+00	3.302	1	5	165
GO:0007264	small GTPase mediated signal transduction	1.02e-01	1.00e+00	3.225	1	4	174
GO:0003713	transcription coactivator activity	1.08e-01	1.00e+00	3.145	1	3	184
GO:0005525	GTP binding	1.15e-01	1.00e+00	3.046	1	3	197
GO:0008134	transcription factor binding	1.22e-01	1.00e+00	2.961	1	5	209
GO:0007268	synaptic transmission	1.25e-01	1.00e+00	2.927	1	1	214
GO:0019901	protein kinase binding	1.34e-01	1.00e+00	2.810	1	8	232
GO:0007411	axon guidance	1.37e-01	1.00e+00	2.780	1	2	237
GO:0000139	Golgi membrane	1.53e-01	1.00e+00	2.608	1	4	267
GO:0005925	focal adhesion	1.61e-01	1.00e+00	2.529	1	12	282
GO:0045892	negative regulation of transcription, DNA-templated	1.80e-01	1.00e+00	2.360	1	1	317
GO:0007596	blood coagulation	1.91e-01	1.00e+00	2.263	1	4	339
GO:0045893	positive regulation of transcription, DNA-templated	2.10e-01	1.00e+00	2.110	1	6	377
GO:0005515	protein binding	2.11e-01	1.00e+00	0.659	4	50	4124
GO:0042803	protein homodimerization activity	2.36e-01	1.00e+00	1.927	1	4	428
GO:0016032	viral process	2.36e-01	1.00e+00	1.927	1	13	428
GO:0045087	innate immune response	2.48e-01	1.00e+00	1.848	1	6	452
GO:0005886	plasma membrane	3.02e-01	1.00e+00	0.868	2	13	1784
GO:0003700	sequence-specific DNA binding transcription factor activity	3.08e-01	1.00e+00	1.484	1	9	582
GO:0005634	nucleus	3.18e-01	1.00e+00	0.589	3	40	3246
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.36e-01	1.00e+00	1.338	1	8	644
GO:0005615	extracellular space	3.39e-01	1.00e+00	1.322	1	2	651
GO:0044822	poly(A) RNA binding	4.01e-01	1.00e+00	1.026	1	25	799
GO:0005654	nucleoplasm	4.31e-01	1.00e+00	0.894	1	16	876
GO:0003677	DNA binding	4.58e-01	1.00e+00	0.781	1	12	947
GO:0006351	transcription, DNA-templated	5.04e-01	1.00e+00	0.597	1	15	1076

Tai-Luciferase

reg-snw-51164

Statistics

Genes (6)

Interactions (7)

Related GO terms (220)