int-snw-115703

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
tai-screen-luciferase 7.396 8.79e-193 1.68e-10 8.31e-05
tai-screen-luciferase-int-snw-115703 subnetwork

Genes (12)

Gene Symbol Entrez Gene ID Frequency tai-screen-luciferase gene score Best subnetwork score Degree List-Gonzales GI Tai-Hits
RPS4X 6191 18-6.7477.555263Yes-
COPZ1 22818 32-8.3019.06313YesYes
COPA 1314 32-9.3959.063170YesYes
CDC42 998 11-6.9608.389265YesYes
RPS27A 6233 15-5.6318.389342Yes-
RPS6 6194 17-5.6038.046208Yes-
RPS24 6229 21-7.0348.389217Yes-
[ ARHGAP33 ] 115703 1-3.0827.3965--
RPS26 6231 17-7.4788.04660Yes-
RPS9 6203 18-7.1277.555140Yes-
ARCN1 372 32-8.2329.063118YesYes
COPB2 9276 32-13.1689.06341YesYes

Interactions (16)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
RPS9 6203 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
CDC42 998 RPS27A 6233 pp -- int.I2D: SOURAV_MAPK_HIGH
RPS4X 6191 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPA 1314 pp -- int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core;
int.HPRD: in vivo
ARCN1 372 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
COPA 1314 COPB2 9276 pp -- int.I2D: BioGrid, HPRD, BCI;
int.HPRD: in vivo
RPS6 6194 RPS27A 6233 pp -- int.I2D: YeastLow
COPA 1314 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
RPS4X 6191 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
CDC42 998 ARHGAP33 115703 pp -- int.I2D: MGI
RPS6 6194 RPS26 6231 pp -- int.I2D: YeastLow
COPA 1314 RPS27A 6233 pp -- int.I2D: YeastLow
RPS6 6194 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS6 6194 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPB2 9276 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vivo
RPS24 6229 RPS27A 6233 pp -- int.I2D: YeastMedium

Related GO terms (233)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0022627cytosolic small ribosomal subunit2.39e-133.44e-097.53162039
GO:0015935small ribosomal subunit9.38e-131.35e-088.4665917
GO:0019083viral transcription2.34e-113.37e-076.47662081
GO:0006415translational termination3.63e-115.23e-076.37362087
GO:0006414translational elongation5.47e-117.88e-076.27762093
GO:0006614SRP-dependent cotranslational protein targeting to membrane1.08e-101.56e-066.116620104
GO:0030126COPI vesicle coat1.35e-101.95e-068.6464712
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.90e-102.74e-065.983620114
GO:0048205COPI coating of Golgi vesicle1.96e-102.82e-068.5314813
GO:0019058viral life cycle2.00e-102.89e-065.971623115
GO:0006413translational initiation4.42e-106.38e-065.783621131
GO:0003735structural constituent of ribosome5.80e-108.37e-065.718622137
GO:0005829cytosol7.06e-101.02e-052.53112612496
GO:0006890retrograde vesicle-mediated transport, Golgi to ER3.44e-094.96e-057.5874825
GO:0016071mRNA metabolic process1.09e-081.58e-045.015625223
GO:0006412translation1.31e-081.90e-044.971623230
GO:0016070RNA metabolic process2.01e-082.90e-044.868625247
GO:0061024membrane organization7.17e-081.03e-035.373512145
GO:0016020membrane6.16e-078.88e-032.6869411681
GO:0036464cytoplasmic ribonucleoprotein granule6.72e-079.69e-037.3573322
GO:0044267cellular protein metabolic process9.53e-071.37e-023.927623474
GO:0016032viral process1.91e-062.76e-023.755633534
GO:0044822poly(A) RNA binding6.32e-069.11e-022.9947321056
GO:0010467gene expression7.08e-061.02e-013.430629669
GO:0006886intracellular protein transport8.77e-061.26e-014.81347171
GO:0042274ribosomal small subunit biogenesis4.17e-056.01e-017.6462612
GO:0006891intra-Golgi vesicle-mediated transport8.57e-051.00e+007.1442417
GO:0030529ribonucleoprotein complex9.53e-051.00e+005.00937112
GO:0005844polysome1.59e-041.00e+006.7082223
GO:0019843rRNA binding2.20e-041.00e+006.4762427
GO:0042059negative regulation of epidermal growth factor receptor signaling pathway3.94e-041.00e+006.0612336
GO:0021691cerebellar Purkinje cell layer maturation8.32e-041.00e+0010.231111
GO:0022605oogenesis stage8.32e-041.00e+0010.231111
GO:0005840ribosome1.02e-031.00e+005.3732858
GO:0071338positive regulation of hair follicle cell proliferation1.66e-031.00e+009.231112
GO:0090135actin filament branching1.66e-031.00e+009.231112
GO:0060661submandibular salivary gland formation1.66e-031.00e+009.231112
GO:0051683establishment of Golgi localization2.49e-031.00e+008.646123
GO:0034191apolipoprotein A-I receptor binding2.49e-031.00e+008.646113
GO:0003161cardiac conduction system development2.49e-031.00e+008.646113
GO:0006364rRNA processing2.66e-031.00e+004.6772794
GO:0005925focal adhesion3.01e-031.00e+003.300319366
GO:0060684epithelial-mesenchymal cell signaling3.32e-031.00e+008.231114
GO:0051835positive regulation of synapse structural plasticity3.32e-031.00e+008.231114
GO:0048664neuron fate determination3.32e-031.00e+008.231114
GO:0072384organelle transport along microtubule3.32e-031.00e+008.231124
GO:0051056regulation of small GTPase mediated signal transduction3.95e-031.00e+004.38624115
GO:0035088establishment or maintenance of apical/basal cell polarity4.15e-031.00e+007.909115
GO:0000462maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)4.15e-031.00e+007.909135
GO:0033119negative regulation of RNA splicing4.15e-031.00e+007.909125
GO:0036336dendritic cell migration4.15e-031.00e+007.909115
GO:0031256leading edge membrane4.15e-031.00e+007.909115
GO:0060789hair follicle placode formation4.98e-031.00e+007.646116
GO:0007097nuclear migration4.98e-031.00e+007.646116
GO:0003334keratinocyte development4.98e-031.00e+007.646116
GO:0002309T cell proliferation involved in immune response4.98e-031.00e+007.646116
GO:0045182translation regulator activity4.98e-031.00e+007.646126
GO:0048554positive regulation of metalloenzyme activity4.98e-031.00e+007.646116
GO:0006924activation-induced cell death of T cells4.98e-031.00e+007.646116
GO:0043497regulation of protein heterodimerization activity4.98e-031.00e+007.646116
GO:0030157pancreatic juice secretion5.81e-031.00e+007.424117
GO:0051988regulation of attachment of spindle microtubules to kinetochore5.81e-031.00e+007.424117
GO:0000028ribosomal small subunit assembly5.81e-031.00e+007.424137
GO:0034101erythrocyte homeostasis5.81e-031.00e+007.424117
GO:0051489regulation of filopodium assembly5.81e-031.00e+007.424117
GO:0000082G1/S transition of mitotic cell cycle6.54e-031.00e+004.01229149
GO:0005198structural molecule activity6.62e-031.00e+004.00226150
GO:0090136epithelial cell-cell adhesion7.47e-031.00e+007.061119
GO:0070062extracellular vesicular exosome7.84e-031.00e+001.5876402400
GO:0031274positive regulation of pseudopodium assembly8.29e-031.00e+006.9091210
GO:0060047heart contraction8.29e-031.00e+006.9091110
GO:0019082viral protein processing9.94e-031.00e+006.6461212
GO:0007173epidermal growth factor receptor signaling pathway1.03e-021.00e+003.66924189
GO:0031929TOR signaling1.08e-021.00e+006.5311113
GO:0032479regulation of type I interferon production1.08e-021.00e+006.5311213
GO:0031333negative regulation of protein complex assembly1.16e-021.00e+006.4241114
GO:0031996thioesterase binding1.16e-021.00e+006.4241114
GO:0030131clathrin adaptor complex1.16e-021.00e+006.4241214
GO:0031369translation initiation factor binding1.24e-021.00e+006.3241115
GO:0048821erythrocyte development1.24e-021.00e+006.3241115
GO:0051233spindle midzone1.24e-021.00e+006.3241215
GO:0030225macrophage differentiation1.24e-021.00e+006.3241115
GO:0042176regulation of protein catabolic process1.32e-021.00e+006.2311316
GO:0030675Rac GTPase activator activity1.32e-021.00e+006.2311116
GO:0075733intracellular transport of virus1.41e-021.00e+006.1441317
GO:0030742GTP-dependent protein binding1.41e-021.00e+006.1441117
GO:0019068virion assembly1.41e-021.00e+006.1441217
GO:0090316positive regulation of intracellular protein transport1.41e-021.00e+006.1441117
GO:0007088regulation of mitosis1.49e-021.00e+006.0611118
GO:0046847filopodium assembly1.57e-021.00e+005.9831119
GO:0007369gastrulation1.57e-021.00e+005.9831119
GO:0043473pigmentation1.65e-021.00e+005.9091120
GO:0031435mitogen-activated protein kinase kinase kinase binding1.73e-021.00e+005.8391121
GO:0031424keratinization1.82e-021.00e+005.7721122
GO:0005737cytoplasm1.82e-021.00e+001.1597433767
GO:0007220Notch receptor processing1.82e-021.00e+005.7721222
GO:1900026positive regulation of substrate adhesion-dependent cell spreading1.90e-021.00e+005.7081123
GO:0002040sprouting angiogenesis1.90e-021.00e+005.7081123
GO:0051017actin filament bundle assembly1.90e-021.00e+005.7081123
GO:0007163establishment or maintenance of cell polarity1.98e-021.00e+005.6461124
GO:0043065positive regulation of apoptotic process2.01e-021.00e+003.16526268
GO:0070423nucleotide-binding oligomerization domain containing signaling pathway2.06e-021.00e+005.5871225
GO:0005978glycogen biosynthetic process2.14e-021.00e+005.5311226
GO:0043552positive regulation of phosphatidylinositol 3-kinase activity2.14e-021.00e+005.5311226
GO:0045859regulation of protein kinase activity2.14e-021.00e+005.5311126
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia2.14e-021.00e+005.5311226
GO:0007264small GTPase mediated signal transduction2.17e-021.00e+003.10727279
GO:0051149positive regulation of muscle cell differentiation2.22e-021.00e+005.4761127
GO:0032467positive regulation of cytokinesis2.22e-021.00e+005.4761127
GO:0031069hair follicle morphogenesis2.22e-021.00e+005.4761127
GO:0072686mitotic spindle2.39e-021.00e+005.3731129
GO:0031647regulation of protein stability2.47e-021.00e+005.3241130
GO:0001890placenta development2.55e-021.00e+005.2771131
GO:0007093mitotic cell cycle checkpoint2.55e-021.00e+005.2771131
GO:0032480negative regulation of type I interferon production2.63e-021.00e+005.2311232
GO:0033077T cell differentiation in thymus2.71e-021.00e+005.1871133
GO:0019901protein kinase binding2.75e-021.00e+002.92326317
GO:0042692muscle cell differentiation2.79e-021.00e+005.1441134
GO:0032855positive regulation of Rac GTPase activity2.87e-021.00e+005.1021135
GO:0034332adherens junction organization2.96e-021.00e+005.0611236
GO:0045740positive regulation of DNA replication2.96e-021.00e+005.0611136
GO:0007249I-kappaB kinase/NF-kappaB signaling3.36e-021.00e+004.8741341
GO:0035872nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway3.52e-021.00e+004.8051243
GO:0021762substantia nigra development3.60e-021.00e+004.7721144
GO:0034613cellular protein localization3.60e-021.00e+004.7721244
GO:0045727positive regulation of translation3.60e-021.00e+004.7721144
GO:0008344adult locomotory behavior3.60e-021.00e+004.7721144
GO:0043525positive regulation of neuron apoptotic process3.76e-021.00e+004.7081246
GO:0044297cell body3.76e-021.00e+004.7081146
GO:0008284positive regulation of cell proliferation3.87e-021.00e+002.65427382
GO:0005730nucleolus3.91e-021.00e+001.5514241641
GO:0007030Golgi organization4.00e-021.00e+004.6161249
GO:0007254JNK cascade4.00e-021.00e+004.6161349
GO:0030175filopodium4.08e-021.00e+004.5871250
GO:0030666endocytic vesicle membrane4.32e-021.00e+004.5031253
GO:0051403stress-activated MAPK cascade4.40e-021.00e+004.4761354
GO:0046330positive regulation of JNK cascade4.48e-021.00e+004.4501155
GO:0016197endosomal transport4.64e-021.00e+004.3981357
GO:0043066negative regulation of apoptotic process4.68e-021.00e+002.503213424
GO:0033138positive regulation of peptidyl-serine phosphorylation4.80e-021.00e+004.3481159
GO:0032481positive regulation of type I interferon production4.96e-021.00e+004.3001361
GO:0035091phosphatidylinositol binding4.96e-021.00e+004.3001161
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway4.96e-021.00e+004.3001261
GO:0030141secretory granule5.04e-021.00e+004.2771162
GO:0006417regulation of translation5.04e-021.00e+004.2771262
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest5.20e-021.00e+004.2311664
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle5.28e-021.00e+004.2091665
GO:0034146toll-like receptor 5 signaling pathway5.28e-021.00e+004.2091465
GO:0031295T cell costimulation5.28e-021.00e+004.2091365
GO:0034166toll-like receptor 10 signaling pathway5.28e-021.00e+004.2091465
GO:0035264multicellular organism growth5.44e-021.00e+004.1651167
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle5.67e-021.00e+004.1021870
GO:0038123toll-like receptor TLR1:TLR2 signaling pathway5.75e-021.00e+004.0811471
GO:0038124toll-like receptor TLR6:TLR2 signaling pathway5.75e-021.00e+004.0811471
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent5.83e-021.00e+004.0611672
GO:0003729mRNA binding5.83e-021.00e+004.0611272
GO:0034162toll-like receptor 9 signaling pathway5.83e-021.00e+004.0611472
GO:0034134toll-like receptor 2 signaling pathway5.91e-021.00e+004.0411473
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis5.99e-021.00e+004.0221274
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle5.99e-021.00e+004.0221874
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I6.07e-021.00e+004.0021675
GO:0060070canonical Wnt signaling pathway6.07e-021.00e+004.0021175
GO:0035666TRIF-dependent toll-like receptor signaling pathway6.15e-021.00e+003.9831476
GO:0010629negative regulation of gene expression6.22e-021.00e+003.9641277
GO:0002756MyD88-independent toll-like receptor signaling pathway6.30e-021.00e+003.9461478
GO:0005179hormone activity6.38e-021.00e+003.9271179
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process6.38e-021.00e+003.9271879
GO:0034138toll-like receptor 3 signaling pathway6.38e-021.00e+003.9271479
GO:0002755MyD88-dependent toll-like receptor signaling pathway6.46e-021.00e+003.9091480
GO:0045177apical part of cell6.54e-021.00e+003.8911181
GO:0050852T cell receptor signaling pathway6.85e-021.00e+003.8221285
GO:0042593glucose homeostasis7.01e-021.00e+003.7881187
GO:0000187activation of MAPK activity7.24e-021.00e+003.7391290
GO:0071456cellular response to hypoxia7.39e-021.00e+003.7081392
GO:0002474antigen processing and presentation of peptide antigen via MHC class I7.39e-021.00e+003.7081692
GO:0034142toll-like receptor 4 signaling pathway7.70e-021.00e+003.6461496
GO:0045087innate immune response8.56e-021.00e+002.01228596
GO:0030496midbody8.63e-021.00e+003.47612108
GO:0002224toll-like receptor signaling pathway8.70e-021.00e+003.46314109
GO:0005815microtubule organizing center8.70e-021.00e+003.46313109
GO:0097190apoptotic signaling pathway9.01e-021.00e+003.41113113
GO:0000209protein polyubiquitination9.24e-021.00e+003.37317116
GO:0006006glucose metabolic process9.39e-021.00e+003.34813118
GO:0007219Notch signaling pathway9.54e-021.00e+003.32413120
GO:0030036actin cytoskeleton organization9.77e-021.00e+003.28912123
GO:0051092positive regulation of NF-kappaB transcription factor activity9.85e-021.00e+003.27713124
GO:0007179transforming growth factor beta receptor signaling pathway1.01e-011.00e+003.23113128
GO:0000086G2/M transition of mitotic cell cycle1.08e-011.00e+003.14415136
GO:0005911cell-cell junction1.08e-011.00e+003.14412136
GO:0008286insulin receptor signaling pathway1.12e-011.00e+003.08113142
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling1.14e-011.00e+003.05113145
GO:0010628positive regulation of gene expression1.15e-011.00e+003.04114146
GO:0034220ion transmembrane transport1.17e-011.00e+003.01212149
GO:0042981regulation of apoptotic process1.18e-011.00e+003.00217150
GO:0010008endosome membrane1.19e-011.00e+002.99315151
GO:0008543fibroblast growth factor receptor signaling pathway1.22e-011.00e+002.94613156
GO:0043005neuron projection1.23e-011.00e+002.93716157
GO:0038095Fc-epsilon receptor signaling pathway1.31e-011.00e+002.83913168
GO:0006367transcription initiation from RNA polymerase II promoter1.43e-011.00e+002.70813184
GO:0003924GTPase activity1.52e-011.00e+002.60917197
GO:0006184GTP catabolic process1.64e-011.00e+002.49017214
GO:0019221cytokine-mediated signaling pathway1.69e-011.00e+002.44312221
GO:0007067mitotic nuclear division1.73e-011.00e+002.40515227
GO:0030425dendrite1.75e-011.00e+002.38612230
GO:0043025neuronal cell body1.86e-011.00e+002.29414245
GO:0005975carbohydrate metabolic process1.91e-011.00e+002.24813253
GO:0000166nucleotide binding1.95e-011.00e+002.21412259
GO:0006281DNA repair1.97e-011.00e+002.20314261
GO:0048011neurotrophin TRK receptor signaling pathway2.02e-011.00e+002.16014269
GO:0005525GTP binding2.30e-011.00e+001.95517310
GO:0007275multicellular organismal development2.34e-011.00e+001.92711316
GO:0043231intracellular membrane-bounded organelle2.35e-011.00e+001.91815318
GO:0007411axon guidance2.35e-011.00e+001.91413319
GO:0015031protein transport2.50e-011.00e+001.81718341
GO:0000139Golgi membrane2.62e-011.00e+001.73516361
GO:0000278mitotic cell cycle2.81e-011.00e+001.620111391
GO:0055085transmembrane transport3.08e-011.00e+001.46613435
GO:0007596blood coagulation3.19e-011.00e+001.40113455
GO:0042802identical protein binding3.36e-011.00e+001.31213484
GO:0048471perinuclear region of cytoplasm3.46e-011.00e+001.26017502
GO:0005886plasma membrane3.67e-011.00e+000.4823202582
GO:0006915apoptotic process3.76e-011.00e+001.11519555
GO:0005783endoplasmic reticulum3.76e-011.00e+001.11213556
GO:0000122negative regulation of transcription from RNA polymerase II promoter3.84e-011.00e+001.07617570
GO:0005794Golgi apparatus4.05e-011.00e+000.97819610
GO:0045944positive regulation of transcription from RNA polymerase II promoter4.91e-011.00e+000.60716789
GO:0005615extracellular space5.61e-011.00e+000.32912957
GO:0005654nucleoplasm6.08e-011.00e+000.1521151082
GO:0005515protein binding6.11e-011.00e+00-0.0035626024
GO:0044281small molecule metabolic process6.51e-011.00e+00-0.0111151211
GO:0046872metal ion binding6.80e-011.00e+00-0.1211101307
GO:0006351transcription, DNA-templated7.19e-011.00e+00-0.267161446
GO:0005634nucleus7.84e-011.00e+00-0.3383434559