reg-snw-9477

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.503	6.24e-09	5.27e-03	4.95e-03

chia-screen-data-Fav-reg-snw-9477 subnetwork

Genes (10)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
SYNCRIP	10492	42	-2.401	2.503	144	TF	Yes	Yes
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
FTSJ1	24140	43	-2.463	2.689	35	-	Yes	Yes
GSPT1	2935	32	-2.313	2.503	17	-	Yes	Yes
ETF1	2107	35	-2.829	2.503	6	-	Yes	Yes
VARS	7407	60	-2.366	2.689	124	TF	Yes	-
[ MED20 ]	9477	1	-1.620	2.503	14	-	-	-
CPSF3	51692	43	-2.686	2.503	31	-	Yes	Yes
NOLC1	9221	15	-1.985	2.503	113	TF	-	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes

Interactions (9)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
GSPT1	2935	NOLC1	9221	pd	<	reg.ITFP.txt: no annot
ETF1	2107	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
NOLC1	9221	MED20	9477	pd	>	reg.ITFP.txt: no annot
VARS	7407	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
NOLC1	9221	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
PHB	5245	VARS	7407	pd	<	reg.ITFP.txt: no annot
GSPT1	2935	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
SYNCRIP	10492	CPSF3	51692	pd	>	reg.ITFP.txt: no annot

Related GO terms (102)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0003747	translation release factor activity	9.44e-07	9.22e-03	9.931	2	2	2
GO:0006479	protein methylation	5.17e-05	5.04e-01	7.472	2	2	11
GO:0004832	valine-tRNA ligase activity	1.02e-03	1.00e+00	9.931	1	1	1
GO:0016149	translation release factor activity, codon specific	1.02e-03	1.00e+00	9.931	1	1	1
GO:0008079	translation termination factor activity	1.02e-03	1.00e+00	9.931	1	1	1
GO:0002128	tRNA nucleoside ribose methylation	1.02e-03	1.00e+00	9.931	1	1	1
GO:0006438	valyl-tRNA aminoacylation	1.02e-03	1.00e+00	9.931	1	1	1
GO:0008175	tRNA methyltransferase activity	1.02e-03	1.00e+00	9.931	1	1	1
GO:0010467	gene expression	1.44e-03	1.00e+00	2.868	4	49	535
GO:0003723	RNA binding	1.68e-03	1.00e+00	3.568	3	22	247
GO:0006415	translational termination	1.78e-03	1.00e+00	4.954	2	2	63
GO:0001649	osteoblast differentiation	2.45e-03	1.00e+00	4.722	2	5	74
GO:0030529	ribonucleoprotein complex	3.00e-03	1.00e+00	4.574	2	5	82
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	3.15e-03	1.00e+00	4.539	2	5	84
GO:0006449	regulation of translational termination	4.09e-03	1.00e+00	7.931	1	1	4
GO:0007000	nucleolus organization	4.09e-03	1.00e+00	7.931	1	1	4
GO:0097452	GAIT complex	4.09e-03	1.00e+00	7.931	1	2	4
GO:0004521	endoribonuclease activity	5.11e-03	1.00e+00	7.610	1	1	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	5.11e-03	1.00e+00	7.610	1	1	5
GO:0002161	aminoacyl-tRNA editing activity	5.11e-03	1.00e+00	7.610	1	1	5
GO:0006398	histone mRNA 3'-end processing	5.11e-03	1.00e+00	7.610	1	1	5
GO:0071204	histone pre-mRNA 3'end processing complex	5.11e-03	1.00e+00	7.610	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	5.11e-03	1.00e+00	7.610	1	2	5
GO:0007049	cell cycle	5.82e-03	1.00e+00	4.086	2	8	115
GO:0050847	progesterone receptor signaling pathway	6.13e-03	1.00e+00	7.347	1	2	6
GO:0002181	cytoplasmic translation	6.13e-03	1.00e+00	7.347	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	6.13e-03	1.00e+00	7.347	1	2	6
GO:0044822	poly(A) RNA binding	6.26e-03	1.00e+00	2.289	4	45	799
GO:0008409	5'-3' exonuclease activity	7.15e-03	1.00e+00	7.124	1	2	7
GO:0000398	mRNA splicing, via spliceosome	7.16e-03	1.00e+00	3.931	2	15	128
GO:0010944	negative regulation of transcription by competitive promoter binding	8.17e-03	1.00e+00	6.931	1	1	8
GO:0010388	cullin deneddylation	8.17e-03	1.00e+00	6.931	1	4	8
GO:0006450	regulation of translational fidelity	8.17e-03	1.00e+00	6.931	1	1	8
GO:0005654	nucleoplasm	8.69e-03	1.00e+00	2.157	4	68	876
GO:0006379	mRNA cleavage	9.18e-03	1.00e+00	6.762	1	2	9
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	9.18e-03	1.00e+00	6.762	1	3	9
GO:0071354	cellular response to interleukin-6	9.18e-03	1.00e+00	6.762	1	1	9
GO:0005095	GTPase inhibitor activity	1.02e-02	1.00e+00	6.610	1	1	10
GO:0008143	poly(A) binding	1.02e-02	1.00e+00	6.610	1	2	10
GO:0060766	negative regulation of androgen receptor signaling pathway	1.12e-02	1.00e+00	6.472	1	4	11
GO:0008380	RNA splicing	1.17e-02	1.00e+00	3.565	2	21	165
GO:0016575	histone deacetylation	1.43e-02	1.00e+00	6.124	1	2	14
GO:0000188	inactivation of MAPK activity	1.53e-02	1.00e+00	6.025	1	1	15
GO:0005525	GTP binding	1.64e-02	1.00e+00	3.309	2	12	197
GO:0043022	ribosome binding	1.73e-02	1.00e+00	5.844	1	2	17
GO:0005515	protein binding	1.78e-02	1.00e+00	0.922	8	198	4124
GO:0003899	DNA-directed RNA polymerase activity	1.83e-02	1.00e+00	5.762	1	3	18
GO:0006378	mRNA polyadenylation	1.83e-02	1.00e+00	5.762	1	3	18
GO:0071346	cellular response to interferon-gamma	2.03e-02	1.00e+00	5.610	1	2	20
GO:0071897	DNA biosynthetic process	2.03e-02	1.00e+00	5.610	1	2	20
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	2.13e-02	1.00e+00	5.539	1	2	21
GO:0008180	COP9 signalosome	2.43e-02	1.00e+00	5.347	1	6	24
GO:0001104	RNA polymerase II transcription cofactor activity	2.43e-02	1.00e+00	5.347	1	4	24
GO:0016592	mediator complex	2.53e-02	1.00e+00	5.288	1	6	25
GO:0006418	tRNA aminoacylation for protein translation	2.93e-02	1.00e+00	5.073	1	4	29
GO:0015030	Cajal body	3.23e-02	1.00e+00	4.931	1	3	32
GO:0017148	negative regulation of translation	3.33e-02	1.00e+00	4.887	1	5	33
GO:0007254	JNK cascade	3.43e-02	1.00e+00	4.844	1	1	34
GO:0031124	mRNA 3'-end processing	3.53e-02	1.00e+00	4.802	1	4	35
GO:0006369	termination of RNA polymerase II transcription	3.83e-02	1.00e+00	4.684	1	5	38
GO:0006396	RNA processing	4.02e-02	1.00e+00	4.610	1	4	40
GO:0006406	mRNA export from nucleus	4.42e-02	1.00e+00	4.472	1	7	44
GO:0006366	transcription from RNA polymerase II promoter	4.55e-02	1.00e+00	2.518	2	23	341
GO:0042826	histone deacetylase binding	5.79e-02	1.00e+00	4.073	1	5	58
GO:0071013	catalytic step 2 spliceosome	6.08e-02	1.00e+00	4.001	1	5	61
GO:0006364	rRNA processing	6.66e-02	1.00e+00	3.865	1	2	67
GO:0030308	negative regulation of cell growth	6.94e-02	1.00e+00	3.802	1	3	70
GO:0005737	cytoplasm	1.03e-01	1.00e+00	0.891	5	127	2633
GO:0042981	regulation of apoptotic process	1.09e-01	1.00e+00	3.124	1	4	112
GO:0003924	GTPase activity	1.15e-01	1.00e+00	3.037	1	7	119
GO:0000082	G1/S transition of mitotic cell cycle	1.21e-01	1.00e+00	2.966	1	4	125
GO:0006184	GTP catabolic process	1.25e-01	1.00e+00	2.909	1	7	130
GO:0044212	transcription regulatory region DNA binding	1.37e-01	1.00e+00	2.772	1	13	143
GO:0005622	intracellular	1.39e-01	1.00e+00	2.752	1	2	145
GO:0005739	mitochondrion	1.43e-01	1.00e+00	1.567	2	32	659
GO:0006367	transcription initiation from RNA polymerase II promoter	1.53e-01	1.00e+00	2.601	1	18	161
GO:0007067	mitotic nuclear division	1.57e-01	1.00e+00	2.565	1	9	165
GO:0016071	mRNA metabolic process	1.61e-01	1.00e+00	2.522	1	10	170
GO:0000166	nucleotide binding	1.66e-01	1.00e+00	2.472	1	13	176
GO:0006412	translation	1.68e-01	1.00e+00	2.456	1	12	178
GO:0016070	RNA metabolic process	1.77e-01	1.00e+00	2.377	1	10	188
GO:0005743	mitochondrial inner membrane	1.84e-01	1.00e+00	2.309	1	9	197
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.90e-01	1.00e+00	2.266	1	14	203
GO:0019899	enzyme binding	1.95e-01	1.00e+00	2.217	1	7	210
GO:0005524	ATP binding	2.31e-01	1.00e+00	1.131	2	37	892
GO:0008285	negative regulation of cell proliferation	2.50e-01	1.00e+00	1.818	1	11	277
GO:0045892	negative regulation of transcription, DNA-templated	2.81e-01	1.00e+00	1.623	1	17	317
GO:0044267	cellular protein metabolic process	3.07e-01	1.00e+00	1.472	1	14	352
GO:0045893	positive regulation of transcription, DNA-templated	3.26e-01	1.00e+00	1.373	1	21	377
GO:0005783	endoplasmic reticulum	3.28e-01	1.00e+00	1.358	1	12	381
GO:0016020	membrane	3.56e-01	1.00e+00	0.694	2	56	1207
GO:0016032	viral process	3.61e-01	1.00e+00	1.190	1	30	428
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.80e-01	1.00e+00	1.099	1	29	456
GO:0005887	integral component of plasma membrane	4.55e-01	1.00e+00	0.764	1	8	575
GO:0007165	signal transduction	4.80e-01	1.00e+00	0.660	1	24	618
GO:0006355	regulation of transcription, DNA-templated	5.33e-01	1.00e+00	0.450	1	31	715
GO:0005829	cytosol	5.71e-01	1.00e+00	0.128	2	88	1787
GO:0046872	metal ion binding	6.34e-01	1.00e+00	0.064	1	24	934
GO:0006351	transcription, DNA-templated	6.89e-01	1.00e+00	-0.140	1	47	1076
GO:0005634	nucleus	6.99e-01	1.00e+00	-0.148	3	158	3246
GO:0005730	nucleolus	7.36e-01	1.00e+00	-0.318	1	74	1217
GO:0070062	extracellular vesicular exosome	8.41e-01	1.00e+00	-0.749	1	51	1641

chia-Fav

reg-snw-9477

Statistics

Genes (10)

Interactions (9)

Related GO terms (102)