reg-snw-9442

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.229	2.05e-07	3.93e-02	3.00e-02

chia-screen-data-Fav-reg-snw-9442 subnetwork

Genes (15)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
SUV39H2	79723	27	-2.307	2.410	21	-	Yes	Yes
SYNCRIP	10492	42	-2.401	2.503	144	TF	Yes	Yes
AGPS	8540	23	-2.424	2.410	27	-	Yes	Yes
ALKBH8	91801	8	-2.147	2.410	5	-	Yes	-
REXO4	57109	5	-1.743	2.287	95	TF	-	-
[ MED27 ]	9442	1	-1.337	2.229	14	-	-	-
EIF2S1	1965	5	-1.801	2.410	63	TF	-	-
GSPT1	2935	32	-2.313	2.503	17	-	Yes	Yes
ETF1	2107	35	-2.829	2.503	6	-	Yes	Yes
PRPF4	9128	5	-1.520	2.342	138	TF	-	-
CLPP	8192	4	-2.200	2.291	10	-	Yes	-
CCT7	10574	40	-2.335	2.459	38	-	Yes	-
CPSF3	51692	43	-2.686	2.503	31	-	Yes	Yes
COPS6	10980	4	-1.765	2.393	18	TF	-	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes

Interactions (17)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
EIF2S1	1965	ETF1	2107	pd	>	reg.ITFP.txt: no annot
PRPF4	9128	MED27	9442	pd	>	reg.ITFP.txt: no annot
GPS1	2873	CLPP	8192	pd	>	reg.ITFP.txt: no annot
PRPF4	9128	REXO4	57109	pd	<>	reg.ITFP.txt: no annot
ETF1	2107	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
CCT7	10574	REXO4	57109	pd	<	reg.ITFP.txt: no annot
MED27	9442	COPS6	10980	pd	<	reg.ITFP.txt: no annot
MED27	9442	REXO4	57109	pd	<	reg.ITFP.txt: no annot
GSPT1	2935	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
CLPP	8192	COPS6	10980	pd	<	reg.ITFP.txt: no annot
EIF2S1	1965	SYNCRIP	10492	pd	<>	reg.ITFP.txt: no annot
AGPS	8540	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
SYNCRIP	10492	SUV39H2	79723	pd	>	reg.ITFP.txt: no annot
EIF2S1	1965	MED27	9442	pd	>	reg.ITFP.txt: no annot
SYNCRIP	10492	CPSF3	51692	pd	>	reg.ITFP.txt: no annot
SYNCRIP	10492	ALKBH8	91801	pd	>	reg.ITFP.txt: no annot
MED27	9442	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot

Related GO terms (142)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0003747	translation release factor activity	2.20e-06	2.15e-02	9.347	2	2	2
GO:0010388	cullin deneddylation	6.13e-05	5.99e-01	7.347	2	4	8
GO:0006479	protein methylation	1.20e-04	1.00e+00	6.887	2	2	11
GO:0043022	ribosome binding	2.96e-04	1.00e+00	6.259	2	2	17
GO:0008180	COP9 signalosome	5.96e-04	1.00e+00	5.762	2	6	24
GO:0000398	mRNA splicing, via spliceosome	8.92e-04	1.00e+00	3.931	3	15	128
GO:0010467	gene expression	9.19e-04	1.00e+00	2.605	5	49	535
GO:0016149	translation release factor activity, codon specific	1.54e-03	1.00e+00	9.347	1	1	1
GO:0016300	tRNA (uracil) methyltransferase activity	1.54e-03	1.00e+00	9.347	1	1	1
GO:0008609	alkylglycerone-phosphate synthase activity	1.54e-03	1.00e+00	9.347	1	1	1
GO:0008079	translation termination factor activity	1.54e-03	1.00e+00	9.347	1	1	1
GO:0006396	RNA processing	1.66e-03	1.00e+00	5.025	2	4	40
GO:0008380	RNA splicing	1.86e-03	1.00e+00	3.565	3	21	165
GO:0043558	regulation of translational initiation in response to stress	3.07e-03	1.00e+00	8.347	1	1	2
GO:0009368	endopeptidase Clp complex	3.07e-03	1.00e+00	8.347	1	1	2
GO:0008611	ether lipid biosynthetic process	3.07e-03	1.00e+00	8.347	1	1	2
GO:0005515	protein binding	3.33e-03	1.00e+00	0.922	12	198	4124
GO:0006415	translational termination	4.07e-03	1.00e+00	4.369	2	2	63
GO:0008762	UDP-N-acetylmuramate dehydrogenase activity	4.60e-03	1.00e+00	7.762	1	1	3
GO:0005850	eukaryotic translation initiation factor 2 complex	4.60e-03	1.00e+00	7.762	1	2	3
GO:0036123	histone H3-K9 dimethylation	4.60e-03	1.00e+00	7.762	1	1	3
GO:0071001	U4/U6 snRNP	4.60e-03	1.00e+00	7.762	1	1	3
GO:0002098	tRNA wobble uridine modification	4.60e-03	1.00e+00	7.762	1	1	3
GO:0044822	poly(A) RNA binding	5.43e-03	1.00e+00	2.026	5	45	799
GO:0003723	RNA binding	5.81e-03	1.00e+00	2.983	3	22	247
GO:0097452	GAIT complex	6.13e-03	1.00e+00	7.347	1	2	4
GO:0006449	regulation of translational termination	6.13e-03	1.00e+00	7.347	1	1	4
GO:0036124	histone H3-K9 trimethylation	6.13e-03	1.00e+00	7.347	1	2	4
GO:0006333	chromatin assembly or disassembly	6.13e-03	1.00e+00	7.347	1	1	4
GO:0005851	eukaryotic translation initiation factor 2B complex	6.13e-03	1.00e+00	7.347	1	2	4
GO:0030529	ribonucleoprotein complex	6.81e-03	1.00e+00	3.989	2	5	82
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	7.14e-03	1.00e+00	3.954	2	5	84
GO:0004521	endoribonuclease activity	7.66e-03	1.00e+00	7.025	1	1	5
GO:0008610	lipid biosynthetic process	7.66e-03	1.00e+00	7.025	1	1	5
GO:0006398	histone mRNA 3'-end processing	7.66e-03	1.00e+00	7.025	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	7.66e-03	1.00e+00	7.025	1	2	5
GO:0071204	histone pre-mRNA 3'end processing complex	7.66e-03	1.00e+00	7.025	1	1	5
GO:0042754	negative regulation of circadian rhythm	9.18e-03	1.00e+00	6.762	1	2	6
GO:0046974	histone methyltransferase activity (H3-K9 specific)	9.18e-03	1.00e+00	6.762	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	9.18e-03	1.00e+00	6.762	1	2	6
GO:0002199	zona pellucida receptor complex	1.07e-02	1.00e+00	6.539	1	4	7
GO:0007140	male meiosis	1.07e-02	1.00e+00	6.539	1	1	7
GO:0008409	5'-3' exonuclease activity	1.07e-02	1.00e+00	6.539	1	2	7
GO:0005832	chaperonin-containing T-complex	1.07e-02	1.00e+00	6.539	1	4	7
GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors	1.22e-02	1.00e+00	6.347	1	1	8
GO:0071949	FAD binding	1.22e-02	1.00e+00	6.347	1	1	8
GO:0030488	tRNA methylation	1.37e-02	1.00e+00	6.177	1	2	9
GO:0006379	mRNA cleavage	1.37e-02	1.00e+00	6.177	1	2	9
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	1.37e-02	1.00e+00	6.177	1	3	9
GO:0044267	cellular protein metabolic process	1.53e-02	1.00e+00	2.472	3	14	352
GO:0005095	GTPase inhibitor activity	1.53e-02	1.00e+00	6.025	1	1	10
GO:0008143	poly(A) binding	1.53e-02	1.00e+00	6.025	1	2	10
GO:0004527	exonuclease activity	1.83e-02	1.00e+00	5.762	1	4	12
GO:0051603	proteolysis involved in cellular protein catabolic process	1.83e-02	1.00e+00	5.762	1	1	12
GO:0000188	inactivation of MAPK activity	2.28e-02	1.00e+00	5.440	1	1	15
GO:0007339	binding of sperm to zona pellucida	2.28e-02	1.00e+00	5.440	1	4	15
GO:0005782	peroxisomal matrix	2.43e-02	1.00e+00	5.347	1	1	16
GO:0006378	mRNA polyadenylation	2.73e-02	1.00e+00	5.177	1	3	18
GO:0000375	RNA splicing, via transesterification reactions	2.73e-02	1.00e+00	5.177	1	1	18
GO:0005844	polysome	2.88e-02	1.00e+00	5.099	1	2	19
GO:0006412	translation	2.97e-02	1.00e+00	2.871	2	12	178
GO:0071346	cellular response to interferon-gamma	3.03e-02	1.00e+00	5.025	1	2	20
GO:0005720	nuclear heterochromatin	3.03e-02	1.00e+00	5.025	1	3	20
GO:0005730	nucleolus	3.06e-02	1.00e+00	1.419	5	74	1217
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	3.18e-02	1.00e+00	4.954	1	2	21
GO:0051084	'de novo' posttranslational protein folding	3.33e-02	1.00e+00	4.887	1	4	22
GO:0000049	tRNA binding	3.48e-02	1.00e+00	4.823	1	2	23
GO:0016592	mediator complex	3.77e-02	1.00e+00	4.703	1	6	25
GO:0000976	transcription regulatory region sequence-specific DNA binding	3.77e-02	1.00e+00	4.703	1	3	25
GO:0010494	cytoplasmic stress granule	3.92e-02	1.00e+00	4.646	1	4	26
GO:0005654	nucleoplasm	3.94e-02	1.00e+00	1.572	4	68	876
GO:0008233	peptidase activity	4.22e-02	1.00e+00	4.539	1	2	28
GO:0005778	peroxisomal membrane	4.37e-02	1.00e+00	4.489	1	3	29
GO:0090305	nucleic acid phosphodiester bond hydrolysis	4.66e-02	1.00e+00	4.392	1	6	31
GO:0015030	Cajal body	4.81e-02	1.00e+00	4.347	1	3	32
GO:0017148	negative regulation of translation	4.95e-02	1.00e+00	4.302	1	5	33
GO:0007254	JNK cascade	5.10e-02	1.00e+00	4.259	1	1	34
GO:0031124	mRNA 3'-end processing	5.25e-02	1.00e+00	4.217	1	4	35
GO:0044297	cell body	5.25e-02	1.00e+00	4.217	1	5	35
GO:0003743	translation initiation factor activity	5.54e-02	1.00e+00	4.137	1	8	37
GO:0006369	termination of RNA polymerase II transcription	5.68e-02	1.00e+00	4.099	1	5	38
GO:0048511	rhythmic process	5.68e-02	1.00e+00	4.099	1	5	38
GO:0019827	stem cell maintenance	5.83e-02	1.00e+00	4.061	1	4	39
GO:0000775	chromosome, centromeric region	6.12e-02	1.00e+00	3.989	1	6	41
GO:0006406	mRNA export from nucleus	6.55e-02	1.00e+00	3.887	1	7	44
GO:0006987	activation of signaling protein activity involved in unfolded protein response	6.99e-02	1.00e+00	3.792	1	1	47
GO:0005777	peroxisome	7.42e-02	1.00e+00	3.703	1	2	50
GO:0005739	mitochondrion	7.58e-02	1.00e+00	1.567	3	32	659
GO:0055114	oxidation-reduction process	7.95e-02	1.00e+00	2.080	2	9	308
GO:0006338	chromatin remodeling	8.13e-02	1.00e+00	3.565	1	7	55
GO:0005681	spliceosomal complex	8.13e-02	1.00e+00	3.565	1	8	55
GO:0005634	nucleus	8.68e-02	1.00e+00	0.682	8	158	3246
GO:0000785	chromatin	8.70e-02	1.00e+00	3.464	1	6	59
GO:0071013	catalytic step 2 spliceosome	8.98e-02	1.00e+00	3.416	1	5	61
GO:0030968	endoplasmic reticulum unfolded protein response	8.98e-02	1.00e+00	3.416	1	1	61
GO:0042802	identical protein binding	1.01e-01	1.00e+00	1.879	2	15	354
GO:0051082	unfolded protein binding	1.02e-01	1.00e+00	3.217	1	5	70
GO:0001649	osteoblast differentiation	1.08e-01	1.00e+00	3.137	1	5	74
GO:0071456	cellular response to hypoxia	1.11e-01	1.00e+00	3.099	1	2	76
GO:0004252	serine-type endopeptidase activity	1.13e-01	1.00e+00	3.061	1	1	78
GO:0051260	protein homooligomerization	1.26e-01	1.00e+00	2.904	1	2	87
GO:0044255	cellular lipid metabolic process	1.28e-01	1.00e+00	2.871	1	2	89
GO:0005506	iron ion binding	1.32e-01	1.00e+00	2.823	1	4	92
GO:0016032	viral process	1.38e-01	1.00e+00	1.605	2	30	428
GO:0006457	protein folding	1.39e-01	1.00e+00	2.747	1	5	97
GO:0006413	translational initiation	1.42e-01	1.00e+00	2.717	1	6	99
GO:0046777	protein autophosphorylation	1.51e-01	1.00e+00	2.619	1	3	106
GO:0007049	cell cycle	1.63e-01	1.00e+00	2.501	1	8	115
GO:0003924	GTPase activity	1.68e-01	1.00e+00	2.452	1	7	119
GO:0006974	cellular response to DNA damage stimulus	1.71e-01	1.00e+00	2.428	1	11	121
GO:0016607	nuclear speck	1.72e-01	1.00e+00	2.416	1	8	122
GO:0000082	G1/S transition of mitotic cell cycle	1.76e-01	1.00e+00	2.381	1	4	125
GO:0006184	GTP catabolic process	1.82e-01	1.00e+00	2.324	1	7	130
GO:0005759	mitochondrial matrix	1.94e-01	1.00e+00	2.228	1	7	139
GO:0005622	intracellular	2.01e-01	1.00e+00	2.167	1	2	145
GO:0005667	transcription factor complex	2.04e-01	1.00e+00	2.147	1	8	147
GO:0006367	transcription initiation from RNA polymerase II promoter	2.21e-01	1.00e+00	2.016	1	18	161
GO:0005874	microtubule	2.23e-01	1.00e+00	1.998	1	10	163
GO:0016071	mRNA metabolic process	2.32e-01	1.00e+00	1.937	1	10	170
GO:0000166	nucleotide binding	2.39e-01	1.00e+00	1.887	1	13	176
GO:0003713	transcription coactivator activity	2.48e-01	1.00e+00	1.823	1	21	184
GO:0016070	RNA metabolic process	2.53e-01	1.00e+00	1.792	1	10	188
GO:0005525	GTP binding	2.64e-01	1.00e+00	1.724	1	12	197
GO:0006357	regulation of transcription from RNA polymerase II promoter	2.70e-01	1.00e+00	1.681	1	14	203
GO:0030154	cell differentiation	2.72e-01	1.00e+00	1.674	1	5	204
GO:0016020	membrane	2.81e-01	1.00e+00	0.694	3	56	1207
GO:0043231	intracellular membrane-bounded organelle	2.87e-01	1.00e+00	1.578	1	8	218
GO:0005829	cytosol	2.89e-01	1.00e+00	0.543	4	88	1787
GO:0008270	zinc ion binding	3.09e-01	1.00e+00	0.841	2	39	727
GO:0003682	chromatin binding	3.25e-01	1.00e+00	1.369	1	15	252
GO:0005737	cytoplasm	3.80e-01	1.00e+00	0.306	5	127	2633
GO:0045892	negative regulation of transcription, DNA-templated	3.91e-01	1.00e+00	1.038	1	17	317
GO:0006366	transcription from RNA polymerase II promoter	4.13e-01	1.00e+00	0.933	1	23	341
GO:0005783	endoplasmic reticulum	4.50e-01	1.00e+00	0.773	1	12	381
GO:0070062	extracellular vesicular exosome	4.74e-01	1.00e+00	0.251	3	51	1641
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	5.12e-01	1.00e+00	0.514	1	29	456
GO:0003700	sequence-specific DNA binding transcription factor activity	6.02e-01	1.00e+00	0.162	1	22	582
GO:0006355	regulation of transcription, DNA-templated	6.81e-01	1.00e+00	-0.135	1	31	715
GO:0044281	small molecule metabolic process	7.43e-01	1.00e+00	-0.375	1	35	844
GO:0005524	ATP binding	7.63e-01	1.00e+00	-0.454	1	37	892
GO:0046872	metal ion binding	7.79e-01	1.00e+00	-0.521	1	24	934
GO:0006351	transcription, DNA-templated	8.27e-01	1.00e+00	-0.725	1	47	1076

chia-Fav

reg-snw-9442

Statistics

Genes (15)

Interactions (17)

Related GO terms (142)