reg-snw-9328

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.204	2.75e-07	4.57e-02	3.47e-02

chia-screen-data-Fav-reg-snw-9328 subnetwork

Genes (13)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
SYNCRIP	10492	42	-2.401	2.503	144	TF	Yes	Yes
[ GTF3C5 ]	9328	1	-1.106	2.204	8	-	-	-
PHB2	11331	17	-2.236	2.449	11	-	Yes	-
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
REXO4	57109	5	-1.743	2.287	95	TF	-	-
NUP93	9688	2	-1.836	2.204	11	-	-	-
POLR2H	5437	2	-1.960	2.204	14	-	-	-
ETF1	2107	35	-2.829	2.503	6	-	Yes	Yes
GSPT1	2935	32	-2.313	2.503	17	-	Yes	Yes
CCT7	10574	40	-2.335	2.459	38	-	Yes	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
IPO4	79711	4	-1.739	2.449	58	TF	-	-
MRPL18	29074	2	-1.788	2.308	15	-	-	-

Interactions (15)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PHB2	11331	IPO4	79711	pd	<	reg.ITFP.txt: no annot
GTF3C5	9328	REXO4	57109	pd	<	reg.ITFP.txt: no annot
ETF1	2107	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
MRPL18	29074	IPO4	79711	pd	<	reg.ITFP.txt: no annot
CCT7	10574	REXO4	57109	pd	<	reg.ITFP.txt: no annot
MRPL18	29074	REXO4	57109	pd	<	reg.ITFP.txt: no annot
GSPT1	2935	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
GTF3C5	9328	IPO4	79711	pd	<	reg.ITFP.txt: no annot
POLR2H	5437	REXO4	57109	pd	<	reg.ITFP.txt: no annot
NUP93	9688	REXO4	57109	pd	<	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
GSPT1	2935	IPO4	79711	pd	<	reg.ITFP.txt: no annot
CCT7	10574	IPO4	79711	pd	<	reg.ITFP.txt: no annot
GPS1	2873	PHB2	11331	pd	>	reg.ITFP.txt: no annot
NUP93	9688	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot

Related GO terms (148)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0003747	translation release factor activity	1.64e-06	1.60e-02	9.553	2	2	2
GO:0006479	protein methylation	8.94e-05	8.73e-01	7.094	2	2	11
GO:0006383	transcription from RNA polymerase III promoter	6.51e-04	1.00e+00	5.695	2	6	29
GO:0016149	translation release factor activity, codon specific	1.33e-03	1.00e+00	9.553	1	1	1
GO:0008079	translation termination factor activity	1.33e-03	1.00e+00	9.553	1	1	1
GO:0005643	nuclear pore	2.01e-03	1.00e+00	4.881	2	12	51
GO:0035928	rRNA import into mitochondrion	2.66e-03	1.00e+00	8.553	1	1	2
GO:0008097	5S rRNA binding	2.66e-03	1.00e+00	8.553	1	1	2
GO:0006415	translational termination	3.05e-03	1.00e+00	4.576	2	2	63
GO:0001649	osteoblast differentiation	4.19e-03	1.00e+00	4.344	2	5	74
GO:0097452	GAIT complex	5.32e-03	1.00e+00	7.553	1	2	4
GO:0006449	regulation of translational termination	5.32e-03	1.00e+00	7.553	1	1	4
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	5.32e-03	1.00e+00	7.553	1	1	4
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	5.36e-03	1.00e+00	4.161	2	5	84
GO:0042797	tRNA transcription from RNA polymerase III promoter	6.64e-03	1.00e+00	7.231	1	3	5
GO:0070934	CRD-mediated mRNA stabilization	6.64e-03	1.00e+00	7.231	1	2	5
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	6.64e-03	1.00e+00	7.231	1	1	5
GO:0060744	mammary gland branching involved in thelarche	6.64e-03	1.00e+00	7.231	1	1	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	6.64e-03	1.00e+00	7.231	1	1	5
GO:0071204	histone pre-mRNA 3'end processing complex	6.64e-03	1.00e+00	7.231	1	1	5
GO:0000127	transcription factor TFIIIC complex	6.64e-03	1.00e+00	7.231	1	3	5
GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter	6.64e-03	1.00e+00	7.231	1	3	5
GO:0050847	progesterone receptor signaling pathway	7.96e-03	1.00e+00	6.968	1	2	6
GO:0001055	RNA polymerase II activity	7.96e-03	1.00e+00	6.968	1	3	6
GO:0070937	CRD-mediated mRNA stability complex	7.96e-03	1.00e+00	6.968	1	2	6
GO:0005739	mitochondrion	8.99e-03	1.00e+00	2.189	4	32	659
GO:0002199	zona pellucida receptor complex	9.28e-03	1.00e+00	6.746	1	4	7
GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	9.28e-03	1.00e+00	6.746	1	2	7
GO:0005832	chaperonin-containing T-complex	9.28e-03	1.00e+00	6.746	1	4	7
GO:0051292	nuclear pore complex assembly	1.06e-02	1.00e+00	6.553	1	4	8
GO:0010944	negative regulation of transcription by competitive promoter binding	1.06e-02	1.00e+00	6.553	1	1	8
GO:0010388	cullin deneddylation	1.06e-02	1.00e+00	6.553	1	4	8
GO:0017056	structural constituent of nuclear pore	1.06e-02	1.00e+00	6.553	1	3	8
GO:0071354	cellular response to interleukin-6	1.19e-02	1.00e+00	6.383	1	1	9
GO:0000398	mRNA splicing, via spliceosome	1.21e-02	1.00e+00	3.553	2	15	128
GO:0005736	DNA-directed RNA polymerase I complex	1.32e-02	1.00e+00	6.231	1	4	10
GO:0005095	GTPase inhibitor activity	1.32e-02	1.00e+00	6.231	1	1	10
GO:0008143	poly(A) binding	1.32e-02	1.00e+00	6.231	1	2	10
GO:0001054	RNA polymerase I activity	1.32e-02	1.00e+00	6.231	1	4	10
GO:0060766	negative regulation of androgen receptor signaling pathway	1.46e-02	1.00e+00	6.094	1	4	11
GO:0004527	exonuclease activity	1.59e-02	1.00e+00	5.968	1	4	12
GO:0034399	nuclear periphery	1.59e-02	1.00e+00	5.968	1	3	12
GO:0006336	DNA replication-independent nucleosome assembly	1.72e-02	1.00e+00	5.853	1	2	13
GO:0005666	DNA-directed RNA polymerase III complex	1.72e-02	1.00e+00	5.853	1	3	13
GO:0005665	DNA-directed RNA polymerase II, core complex	1.72e-02	1.00e+00	5.853	1	3	13
GO:0001056	RNA polymerase III activity	1.72e-02	1.00e+00	5.853	1	3	13
GO:0060749	mammary gland alveolus development	1.72e-02	1.00e+00	5.853	1	1	13
GO:0016032	viral process	1.72e-02	1.00e+00	2.396	3	30	428
GO:0006335	DNA replication-dependent nucleosome assembly	1.72e-02	1.00e+00	5.853	1	2	13
GO:0044822	poly(A) RNA binding	1.75e-02	1.00e+00	1.911	4	45	799
GO:0006386	termination of RNA polymerase III transcription	1.85e-02	1.00e+00	5.746	1	3	14
GO:0006385	transcription elongation from RNA polymerase III promoter	1.85e-02	1.00e+00	5.746	1	3	14
GO:0016575	histone deacetylation	1.85e-02	1.00e+00	5.746	1	2	14
GO:0008380	RNA splicing	1.96e-02	1.00e+00	3.187	2	21	165
GO:0000188	inactivation of MAPK activity	1.98e-02	1.00e+00	5.646	1	1	15
GO:0007339	binding of sperm to zona pellucida	1.98e-02	1.00e+00	5.646	1	4	15
GO:0043022	ribosome binding	2.24e-02	1.00e+00	5.466	1	2	17
GO:0006412	translation	2.26e-02	1.00e+00	3.077	2	12	178
GO:0005654	nucleoplasm	2.38e-02	1.00e+00	1.778	4	68	876
GO:0006362	transcription elongation from RNA polymerase I promoter	2.63e-02	1.00e+00	5.231	1	3	20
GO:0005761	mitochondrial ribosome	2.63e-02	1.00e+00	5.231	1	1	20
GO:0071346	cellular response to interferon-gamma	2.63e-02	1.00e+00	5.231	1	2	20
GO:0071897	DNA biosynthetic process	2.63e-02	1.00e+00	5.231	1	2	20
GO:0005743	mitochondrial inner membrane	2.73e-02	1.00e+00	2.931	2	9	197
GO:0008536	Ran GTPase binding	2.76e-02	1.00e+00	5.161	1	1	21
GO:0006363	termination of RNA polymerase I transcription	2.76e-02	1.00e+00	5.161	1	3	21
GO:0015031	protein transport	2.89e-02	1.00e+00	2.888	2	10	203
GO:0030331	estrogen receptor binding	2.89e-02	1.00e+00	5.094	1	2	22
GO:0051084	'de novo' posttranslational protein folding	2.89e-02	1.00e+00	5.094	1	4	22
GO:0006361	transcription initiation from RNA polymerase I promoter	3.02e-02	1.00e+00	5.029	1	2	23
GO:0043234	protein complex	3.07e-02	1.00e+00	2.839	2	13	210
GO:0010467	gene expression	3.10e-02	1.00e+00	2.075	3	49	535
GO:0006370	7-methylguanosine mRNA capping	3.15e-02	1.00e+00	4.968	1	5	24
GO:0008180	COP9 signalosome	3.15e-02	1.00e+00	4.968	1	6	24
GO:0010827	regulation of glucose transport	3.28e-02	1.00e+00	4.909	1	7	25
GO:0006360	transcription from RNA polymerase I promoter	3.54e-02	1.00e+00	4.798	1	4	27
GO:0090305	nucleic acid phosphodiester bond hydrolysis	4.05e-02	1.00e+00	4.599	1	6	31
GO:0003723	RNA binding	4.14e-02	1.00e+00	2.605	2	22	247
GO:0007077	mitotic nuclear envelope disassembly	4.18e-02	1.00e+00	4.553	1	9	32
GO:0017148	negative regulation of translation	4.31e-02	1.00e+00	4.509	1	5	33
GO:0035914	skeletal muscle cell differentiation	4.31e-02	1.00e+00	4.509	1	3	33
GO:0007254	JNK cascade	4.44e-02	1.00e+00	4.466	1	1	34
GO:0050434	positive regulation of viral transcription	4.56e-02	1.00e+00	4.424	1	5	35
GO:0044297	cell body	4.56e-02	1.00e+00	4.424	1	5	35
GO:0008645	hexose transport	4.69e-02	1.00e+00	4.383	1	8	36
GO:0006396	RNA processing	5.20e-02	1.00e+00	4.231	1	4	40
GO:0006283	transcription-coupled nucleotide-excision repair	5.20e-02	1.00e+00	4.231	1	6	40
GO:0051028	mRNA transport	6.08e-02	1.00e+00	3.998	1	5	47
GO:0032481	positive regulation of type I interferon production	6.21e-02	1.00e+00	3.968	1	3	48
GO:0015758	glucose transport	6.21e-02	1.00e+00	3.968	1	8	48
GO:0045892	negative regulation of transcription, DNA-templated	6.47e-02	1.00e+00	2.245	2	17	317
GO:0016020	membrane	6.65e-02	1.00e+00	1.316	4	56	1207
GO:0006368	transcription elongation from RNA polymerase II promoter	6.71e-02	1.00e+00	3.853	1	8	52
GO:0006289	nucleotide-excision repair	6.83e-02	1.00e+00	3.825	1	6	53
GO:0042826	histone deacetylase binding	7.46e-02	1.00e+00	3.695	1	5	58
GO:0044267	cellular protein metabolic process	7.78e-02	1.00e+00	2.094	2	14	352
GO:0071013	catalytic step 2 spliceosome	7.83e-02	1.00e+00	3.622	1	5	61
GO:0030308	negative regulation of cell growth	8.93e-02	1.00e+00	3.424	1	3	70
GO:0051082	unfolded protein binding	8.93e-02	1.00e+00	3.424	1	5	70
GO:0016363	nuclear matrix	9.30e-02	1.00e+00	3.363	1	10	73
GO:0030529	ribonucleoprotein complex	1.04e-01	1.00e+00	3.195	1	5	82
GO:0005635	nuclear envelope	1.05e-01	1.00e+00	3.178	1	6	83
GO:0006886	intracellular protein transport	1.12e-01	1.00e+00	3.077	1	2	89
GO:0006457	protein folding	1.22e-01	1.00e+00	2.953	1	5	97
GO:0005515	protein binding	1.30e-01	1.00e+00	0.543	8	198	4124
GO:0003735	structural constituent of ribosome	1.36e-01	1.00e+00	2.785	1	2	109
GO:0000790	nuclear chromatin	1.36e-01	1.00e+00	2.785	1	9	109
GO:0042981	regulation of apoptotic process	1.39e-01	1.00e+00	2.746	1	4	112
GO:0007049	cell cycle	1.43e-01	1.00e+00	2.707	1	8	115
GO:0003924	GTPase activity	1.47e-01	1.00e+00	2.658	1	7	119
GO:0000082	G1/S transition of mitotic cell cycle	1.54e-01	1.00e+00	2.587	1	4	125
GO:0031965	nuclear membrane	1.60e-01	1.00e+00	2.531	1	8	130
GO:0006184	GTP catabolic process	1.60e-01	1.00e+00	2.531	1	7	130
GO:0044212	transcription regulatory region DNA binding	1.75e-01	1.00e+00	2.393	1	13	143
GO:0005622	intracellular	1.77e-01	1.00e+00	2.373	1	2	145
GO:0006367	transcription initiation from RNA polymerase II promoter	1.94e-01	1.00e+00	2.222	1	18	161
GO:0005874	microtubule	1.97e-01	1.00e+00	2.204	1	10	163
GO:0016071	mRNA metabolic process	2.04e-01	1.00e+00	2.144	1	10	170
GO:0019221	cytokine-mediated signaling pathway	2.06e-01	1.00e+00	2.127	1	10	172
GO:0000166	nucleotide binding	2.11e-01	1.00e+00	2.094	1	13	176
GO:0005975	carbohydrate metabolic process	2.21e-01	1.00e+00	2.014	1	10	186
GO:0016070	RNA metabolic process	2.23e-01	1.00e+00	1.998	1	10	188
GO:0005525	GTP binding	2.33e-01	1.00e+00	1.931	1	12	197
GO:0005634	nucleus	2.39e-01	1.00e+00	0.473	6	158	3246
GO:0006281	DNA repair	2.39e-01	1.00e+00	1.888	1	24	203
GO:0006355	regulation of transcription, DNA-templated	2.46e-01	1.00e+00	1.071	2	31	715
GO:0019899	enzyme binding	2.46e-01	1.00e+00	1.839	1	7	210
GO:0005737	cytoplasm	2.58e-01	1.00e+00	0.512	5	127	2633
GO:0008285	negative regulation of cell proliferation	3.12e-01	1.00e+00	1.439	1	11	277
GO:0000278	mitotic cell cycle	3.46e-01	1.00e+00	1.258	1	28	314
GO:0055085	transmembrane transport	3.60e-01	1.00e+00	1.191	1	13	329
GO:0003677	DNA binding	3.64e-01	1.00e+00	0.666	2	52	947
GO:0006366	transcription from RNA polymerase II promoter	3.70e-01	1.00e+00	1.139	1	23	341
GO:0070062	extracellular vesicular exosome	3.77e-01	1.00e+00	0.458	3	51	1641
GO:0042802	identical protein binding	3.81e-01	1.00e+00	1.085	1	15	354
GO:0045893	positive regulation of transcription, DNA-templated	4.01e-01	1.00e+00	0.995	1	21	377
GO:0005783	endoplasmic reticulum	4.04e-01	1.00e+00	0.979	1	12	381
GO:0006351	transcription, DNA-templated	4.28e-01	1.00e+00	0.482	2	47	1076
GO:0005829	cytosol	4.35e-01	1.00e+00	0.335	3	88	1787
GO:0045087	innate immune response	4.60e-01	1.00e+00	0.733	1	12	452
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	4.63e-01	1.00e+00	0.720	1	29	456
GO:0005887	integral component of plasma membrane	5.46e-01	1.00e+00	0.386	1	8	575
GO:0003700	sequence-specific DNA binding transcription factor activity	5.50e-01	1.00e+00	0.368	1	22	582
GO:0007165	signal transduction	5.73e-01	1.00e+00	0.282	1	24	618
GO:0005615	extracellular space	5.92e-01	1.00e+00	0.206	1	15	651
GO:0044281	small molecule metabolic process	6.91e-01	1.00e+00	-0.168	1	35	844
GO:0005524	ATP binding	7.12e-01	1.00e+00	-0.248	1	37	892
GO:0005730	nucleolus	8.23e-01	1.00e+00	-0.696	1	74	1217

chia-Fav

reg-snw-9328

Statistics

Genes (13)

Interactions (15)

Related GO terms (148)