reg-snw-83990

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.201 2.85e-07 4.66e-02 3.54e-02
chia-screen-data-Fav-reg-snw-83990 subnetwork

Genes (19)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
NDUFA4L2 56901 44-2.4772.45921-Yes-
AGPS 8540 23-2.4242.41027-YesYes
[ BRIP1 ] 83990 1-1.2932.20181TF--
PGM5 5239 1-1.7302.2014---
PHB 5245 82-2.7432.68936-YesYes
NDC80 10403 1-1.8112.20124---
VARS 7407 60-2.3662.689124TFYes-
CHEK1 1111 2-1.5112.28882---
NUP160 23279 3-1.5292.38750---
NUP205 23165 1-1.7172.20133---
FBXO22 26263 36-1.7392.459208TF--
TPR 7175 10-2.6382.44536TFYesYes
NCBP1 4686 41-2.5102.45944-YesYes
EIF2S2 8894 40-2.9992.45922-YesYes
TTF2 8458 6-1.6462.38276TF--
CENPQ 55166 20-2.1372.45916-Yes-
CCT7 10574 40-2.3352.45938-Yes-
GPS1 2873 86-3.6212.68936TFYesYes
POLH 5429 36-2.5862.45924-YesYes

Interactions (24)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
NDC80 10403 BRIP1 83990 pd < reg.ITFP.txt: no annot
VARS 7407 FBXO22 26263 pd <> reg.ITFP.txt: no annot
CHEK1 1111 BRIP1 83990 pd < reg.ITFP.txt: no annot
CHEK1 1111 FBXO22 26263 pd < reg.ITFP.txt: no annot
PHB 5245 VARS 7407 pd < reg.ITFP.txt: no annot
TTF2 8458 BRIP1 83990 pd <> reg.ITFP.txt: no annot
NUP160 23279 FBXO22 26263 pd < reg.ITFP.txt: no annot
PHB 5245 FBXO22 26263 pd < reg.ITFP.txt: no annot
POLH 5429 FBXO22 26263 pd < reg.ITFP.txt: no annot
FBXO22 26263 CENPQ 55166 pd > reg.ITFP.txt: no annot
NCBP1 4686 BRIP1 83990 pd < reg.ITFP.txt: no annot
NCBP1 4686 FBXO22 26263 pd < reg.ITFP.txt: no annot
NUP205 23165 BRIP1 83990 pd < reg.ITFP.txt: no annot
NUP160 23279 BRIP1 83990 pd < reg.ITFP.txt: no annot
PGM5 5239 BRIP1 83990 pd < reg.ITFP.txt: no annot
NCBP1 4686 TPR 7175 pd < reg.ITFP.txt: no annot
CHEK1 1111 TTF2 8458 pd < reg.ITFP.txt: no annot
EIF2S2 8894 FBXO22 26263 pd < reg.ITFP.txt: no annot
CENPQ 55166 BRIP1 83990 pd < reg.ITFP.txt: no annot
FBXO22 26263 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot
CCT7 10574 FBXO22 26263 pd < reg.ITFP.txt: no annot
TTF2 8458 AGPS 8540 pd > reg.ITFP.txt: no annot
FBXO22 26263 BRIP1 83990 pd <> reg.ITFP.txt: no annot

Related GO terms (250)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0010827regulation of glucose transport1.40e-051.37e-015.9473725
GO:0007077mitotic nuclear envelope disassembly2.99e-052.92e-015.5903932
GO:0008645hexose transport4.28e-054.18e-015.4213836
GO:0051292nuclear pore complex assembly9.97e-059.74e-017.005248
GO:0015758glucose transport1.02e-049.98e-015.0053848
GO:0005643nuclear pore1.23e-041.00e+004.91831251
GO:0000776kinetochore1.54e-041.00e+004.8093855
GO:0005487nucleocytoplasmic transporter activity1.95e-041.00e+006.5462211
GO:0034399nuclear periphery2.34e-041.00e+006.4212312
GO:0000278mitotic cell cycle2.67e-041.00e+003.033528314
GO:0005635nuclear envelope5.20e-041.00e+004.2153683
GO:0006913nucleocytoplasmic transport6.67e-041.00e+005.6842220
GO:0000077DNA damage checkpoint7.37e-041.00e+005.6132421
GO:0031965nuclear membrane1.91e-031.00e+003.56838130
GO:0004832valine-tRNA ligase activity1.95e-031.00e+009.005111
GO:1901673regulation of spindle assembly involved in mitosis1.95e-031.00e+009.005111
GO:2000615regulation of histone H3-K9 acetylation1.95e-031.00e+009.005111
GO:0043578nuclear matrix organization1.95e-031.00e+009.005111
GO:0010767regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage1.95e-031.00e+009.005111
GO:0035407histone H3-T11 phosphorylation1.95e-031.00e+009.005111
GO:0035402histone kinase activity (H3-T11 specific)1.95e-031.00e+009.005111
GO:0010965regulation of mitotic sister chromatid separation1.95e-031.00e+009.005111
GO:0005914spot adherens junction1.95e-031.00e+009.005111
GO:0008609alkylglycerone-phosphate synthase activity1.95e-031.00e+009.005111
GO:0006404RNA import into nucleus1.95e-031.00e+009.005111
GO:0006438valyl-tRNA aminoacylation1.95e-031.00e+009.005111
GO:0031453positive regulation of heterochromatin assembly1.95e-031.00e+009.005111
GO:0006369termination of RNA polymerase II transcription2.42e-031.00e+004.7582538
GO:0000775chromosome, centromeric region2.81e-031.00e+004.6482641
GO:0006406mRNA export from nucleus3.23e-031.00e+004.5462744
GO:0005829cytosol3.55e-031.00e+001.3729881787
GO:0000189MAPK import into nucleus3.89e-031.00e+008.005112
GO:0048742regulation of skeletal muscle fiber development3.89e-031.00e+008.005112
GO:0010972negative regulation of G2/M transition of mitotic cell cycle3.89e-031.00e+008.005112
GO:0031990mRNA export from nucleus in response to heat stress3.89e-031.00e+008.005112
GO:0006353DNA-templated transcription, termination3.89e-031.00e+008.005112
GO:0042306regulation of protein import into nucleus3.89e-031.00e+008.005112
GO:0005846nuclear cap binding complex3.89e-031.00e+008.005112
GO:0002176male germ cell proliferation3.89e-031.00e+008.005112
GO:0046602regulation of mitotic centrosome separation3.89e-031.00e+008.005112
GO:0070840dynein complex binding3.89e-031.00e+008.005112
GO:0000059protein import into nucleus, docking3.89e-031.00e+008.005112
GO:0008611ether lipid biosynthetic process3.89e-031.00e+008.005112
GO:0046832negative regulation of RNA export from nucleus3.89e-031.00e+008.005112
GO:0019221cytokine-mediated signaling pathway4.23e-031.00e+003.164310172
GO:0005654nucleoplasm5.01e-031.00e+001.816668876
GO:0005975carbohydrate metabolic process5.26e-031.00e+003.051310186
GO:0008762UDP-N-acetylmuramate dehydrogenase activity5.83e-031.00e+007.421113
GO:0005850eukaryotic translation initiation factor 2 complex5.83e-031.00e+007.421123
GO:0006405RNA export from nucleus5.83e-031.00e+007.421113
GO:0000942condensed nuclear chromosome outer kinetochore5.83e-031.00e+007.421123
GO:0010793regulation of mRNA export from nucleus5.83e-031.00e+007.421113
GO:0030018Z disc6.73e-031.00e+004.0052364
GO:0005739mitochondrion7.24e-031.00e+001.963532659
GO:0045292mRNA cis splicing, via spliceosome7.76e-031.00e+007.005114
GO:0031262Ndc80 complex7.76e-031.00e+007.005114
GO:0031442positive regulation of mRNA 3'-end processing7.76e-031.00e+007.005114
GO:0006290pyrimidine dimer repair7.76e-031.00e+007.005124
GO:0006999nuclear pore organization7.76e-031.00e+007.005114
GO:0070849response to epidermal growth factor7.76e-031.00e+007.005114
GO:0044615nuclear pore nuclear basket7.76e-031.00e+007.005114
GO:0004614phosphoglucomutase activity7.76e-031.00e+007.005114
GO:0016032viral process8.35e-031.00e+002.264430428
GO:0008610lipid biosynthetic process9.69e-031.00e+006.684115
GO:0046825regulation of protein export from nucleus9.69e-031.00e+006.684115
GO:0043495protein anchor9.69e-031.00e+006.684115
GO:0006282regulation of DNA repair9.69e-031.00e+006.684125
GO:0048096chromatin-mediated maintenance of transcription9.69e-031.00e+006.684115
GO:2000323negative regulation of glucocorticoid receptor signaling pathway9.69e-031.00e+006.684115
GO:0002161aminoacyl-tRNA editing activity9.69e-031.00e+006.684115
GO:0071313cellular response to caffeine9.69e-031.00e+006.684115
GO:0050847progesterone receptor signaling pathway1.16e-021.00e+006.421126
GO:0008608attachment of spindle microtubules to kinetochore1.16e-021.00e+006.421116
GO:2000279negative regulation of DNA biosynthetic process1.16e-021.00e+006.421116
GO:0090267positive regulation of mitotic cell cycle spindle assembly checkpoint1.16e-021.00e+006.421116
GO:0006975DNA damage induced protein phosphorylation1.16e-021.00e+006.421116
GO:0045839negative regulation of mitosis1.16e-021.00e+006.421116
GO:0002199zona pellucida receptor complex1.35e-021.00e+006.198147
GO:0000731DNA synthesis involved in DNA repair1.35e-021.00e+006.198117
GO:0006301postreplication repair1.35e-021.00e+006.198127
GO:0000339RNA cap binding1.35e-021.00e+006.198117
GO:0005832chaperonin-containing T-complex1.35e-021.00e+006.198147
GO:0005868cytoplasmic dynein complex1.35e-021.00e+006.198117
GO:0019388galactose catabolic process1.35e-021.00e+006.198117
GO:0090399replicative senescence1.35e-021.00e+006.198117
GO:0006260DNA replication1.41e-021.00e+003.4512994
GO:0005845mRNA cap binding complex1.55e-021.00e+006.005118
GO:0042405nuclear inclusion body1.55e-021.00e+006.005118
GO:0006450regulation of translational fidelity1.55e-021.00e+006.005118
GO:0010944negative regulation of transcription by competitive promoter binding1.55e-021.00e+006.005118
GO:0071949FAD binding1.55e-021.00e+006.005118
GO:0010388cullin deneddylation1.55e-021.00e+006.005148
GO:0035457cellular response to interferon-alpha1.55e-021.00e+006.005118
GO:0017056structural constituent of nuclear pore1.55e-021.00e+006.005138
GO:0031080nuclear pore outer ring1.74e-021.00e+005.836129
GO:0010225response to UV-C1.74e-021.00e+005.836129
GO:0006379mRNA cleavage1.74e-021.00e+005.836129
GO:0045947negative regulation of translational initiation1.74e-021.00e+005.836119
GO:0071354cellular response to interleukin-61.74e-021.00e+005.836119
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process1.74e-021.00e+005.836129
GO:0010569regulation of double-strand break repair via homologous recombination1.74e-021.00e+005.836119
GO:0005515protein binding1.92e-021.00e+000.696131984124
GO:0005095GTPase inhibitor activity1.93e-021.00e+005.6841110
GO:0016010dystrophin-associated glycoprotein complex1.93e-021.00e+005.6841110
GO:0044281small molecule metabolic process1.99e-021.00e+001.606535844
GO:0060766negative regulation of androgen receptor signaling pathway2.12e-021.00e+005.5461411
GO:0051019mitogen-activated protein kinase binding2.12e-021.00e+005.5461111
GO:0008023transcription elongation factor complex2.12e-021.00e+005.5461211
GO:0008334histone mRNA metabolic process2.12e-021.00e+005.5461111
GO:0090316positive regulation of intracellular protein transport2.12e-021.00e+005.5461111
GO:0046827positive regulation of protein export from nucleus2.12e-021.00e+005.5461111
GO:0042307positive regulation of protein import into nucleus2.31e-021.00e+005.4211312
GO:0000132establishment of mitotic spindle orientation2.31e-021.00e+005.4211212
GO:0055085transmembrane transport2.46e-021.00e+002.228313329
GO:0005524ATP binding2.47e-021.00e+001.527537892
GO:0016575histone deacetylation2.69e-021.00e+005.1981214
GO:0005978glycogen biosynthetic process2.88e-021.00e+005.0991215
GO:0008135translation factor activity, nucleic acid binding2.88e-021.00e+005.0991415
GO:0031572G2 DNA damage checkpoint2.88e-021.00e+005.0991215
GO:0000188inactivation of MAPK activity2.88e-021.00e+005.0991115
GO:0007339binding of sperm to zona pellucida2.88e-021.00e+005.0991415
GO:0043034costamere2.88e-021.00e+005.0991215
GO:0003887DNA-directed DNA polymerase activity3.07e-021.00e+005.0051216
GO:0005782peroxisomal matrix3.07e-021.00e+005.0051116
GO:0005657replication fork3.07e-021.00e+005.0051316
GO:0007052mitotic spindle organization3.26e-021.00e+004.9181317
GO:0000070mitotic sister chromatid segregation3.26e-021.00e+004.9181217
GO:0006611protein export from nucleus3.45e-021.00e+004.8361118
GO:0031047gene silencing by RNA3.45e-021.00e+004.8361218
GO:0000794condensed nuclear chromosome3.45e-021.00e+004.8361118
GO:0015631tubulin binding3.82e-021.00e+004.6841120
GO:0034080CENP-A containing nucleosome assembly3.82e-021.00e+004.6841220
GO:0072686mitotic spindle3.82e-021.00e+004.6841220
GO:0071897DNA biosynthetic process3.82e-021.00e+004.6841220
GO:0034660ncRNA metabolic process3.82e-021.00e+004.6841120
GO:0031647regulation of protein stability4.01e-021.00e+004.6131221
GO:00515394 iron, 4 sulfur cluster binding4.01e-021.00e+004.6131421
GO:0008380RNA splicing4.02e-021.00e+002.639221165
GO:0007067mitotic nuclear division4.02e-021.00e+002.63929165
GO:0006606protein import into nucleus4.20e-021.00e+004.5461322
GO:0051084'de novo' posttranslational protein folding4.20e-021.00e+004.5461422
GO:0000387spliceosomal snRNP assembly4.20e-021.00e+004.5461122
GO:0034605cellular response to heat4.20e-021.00e+004.5461122
GO:0014704intercalated disc4.39e-021.00e+004.4821223
GO:00063707-methylguanosine mRNA capping4.57e-021.00e+004.4211524
GO:0008180COP9 signalosome4.57e-021.00e+004.4211624
GO:0004003ATP-dependent DNA helicase activity4.76e-021.00e+004.3621325
GO:0005913cell-cell adherens junction4.76e-021.00e+004.3621325
GO:0007094mitotic spindle assembly checkpoint4.76e-021.00e+004.3621425
GO:0009267cellular response to starvation4.94e-021.00e+004.3051126
GO:0031072heat shock protein binding5.31e-021.00e+004.1981128
GO:0009898cytoplasmic side of plasma membrane5.31e-021.00e+004.1981328
GO:0006418tRNA aminoacylation for protein translation5.50e-021.00e+004.1471429
GO:0008094DNA-dependent ATPase activity5.50e-021.00e+004.1471629
GO:0018107peptidyl-threonine phosphorylation5.50e-021.00e+004.1471129
GO:0000781chromosome, telomeric region5.50e-021.00e+004.1471229
GO:0008026ATP-dependent helicase activity5.50e-021.00e+004.1471329
GO:0005778peroxisomal membrane5.50e-021.00e+004.1471329
GO:0006446regulation of translational initiation5.50e-021.00e+004.1471229
GO:0019898extrinsic component of membrane5.68e-021.00e+004.0991130
GO:0006281DNA repair5.83e-021.00e+002.340224203
GO:0045111intermediate filament cytoskeleton5.87e-021.00e+004.0511331
GO:0007254JNK cascade6.42e-021.00e+003.9181134
GO:0050434positive regulation of viral transcription6.60e-021.00e+003.8761535
GO:0031124mRNA 3'-end processing6.60e-021.00e+003.8761435
GO:0044297cell body6.60e-021.00e+003.8761535
GO:0043231intracellular membrane-bounded organelle6.61e-021.00e+002.23728218
GO:0006200ATP catabolic process6.67e-021.00e+002.231213219
GO:0003743translation initiation factor activity6.97e-021.00e+003.7961837
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process7.15e-021.00e+003.7581438
GO:0032508DNA duplex unwinding7.15e-021.00e+003.7581338
GO:0042383sarcolemma7.69e-021.00e+003.6481141
GO:0003684damaged DNA binding7.69e-021.00e+003.6481141
GO:0003723RNA binding8.22e-021.00e+002.057222247
GO:0010467gene expression8.25e-021.00e+001.527349535
GO:0001725stress fiber8.59e-021.00e+003.4821646
GO:0051028mRNA transport8.77e-021.00e+003.4511547
GO:0007059chromosome segregation9.30e-021.00e+003.3621450
GO:0005777peroxisome9.30e-021.00e+003.3621250
GO:0006334nucleosome assembly9.48e-021.00e+003.3331451
GO:0006368transcription elongation from RNA polymerase II promoter9.66e-021.00e+003.3051852
GO:0006302double-strand break repair9.66e-021.00e+003.3051552
GO:0005681spliceosomal complex1.02e-011.00e+003.2241855
GO:0071260cellular response to mechanical stimulus1.02e-011.00e+003.2241255
GO:0008584male gonad development1.05e-011.00e+003.1731157
GO:0003729mRNA binding1.05e-011.00e+003.1731457
GO:0000777condensed chromosome kinetochore1.05e-011.00e+003.1731657
GO:0042826histone deacetylase binding1.07e-011.00e+003.1471558
GO:0000785chromatin1.09e-011.00e+003.1231659
GO:0005737cytoplasm1.12e-011.00e+000.64381272633
GO:0006464cellular protein modification process1.12e-011.00e+003.0751461
GO:0030308negative regulation of cell growth1.28e-011.00e+002.8761370
GO:0051082unfolded protein binding1.28e-011.00e+002.8761570
GO:0001649osteoblast differentiation1.35e-011.00e+002.7961574
GO:0005634nucleus1.44e-011.00e+000.51191583246
GO:0006006glucose metabolic process1.45e-011.00e+002.6841380
GO:0042127regulation of cell proliferation1.45e-011.00e+002.6841480
GO:0030529ribonucleoprotein complex1.48e-011.00e+002.6481582
GO:0044267cellular protein metabolic process1.48e-011.00e+001.546214352
GO:0005215transporter activity1.48e-011.00e+002.6481582
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.52e-011.00e+002.6131584
GO:0044255cellular lipid metabolic process1.60e-011.00e+002.5301289
GO:0000209protein polyubiquitination1.65e-011.00e+002.4821692
GO:0006511ubiquitin-dependent protein catabolic process1.65e-011.00e+002.4821692
GO:0000086G2/M transition of mitotic cell cycle1.73e-011.00e+002.4061797
GO:0006457protein folding1.73e-011.00e+002.4061597
GO:0006413translational initiation1.76e-011.00e+002.3761699
GO:0005198structural molecule activity1.79e-011.00e+002.34714101
GO:0006397mRNA processing1.94e-011.00e+002.224112110
GO:0042981regulation of apoptotic process1.97e-011.00e+002.19814112
GO:0044822poly(A) RNA binding2.00e-011.00e+000.948345799
GO:0016020membrane2.01e-011.00e+000.7684561207
GO:0000287magnesium ion binding2.02e-011.00e+002.16014115
GO:0007049cell cycle2.02e-011.00e+002.16018115
GO:0005730nucleolus2.05e-011.00e+000.7564741217
GO:0006974cellular response to DNA damage stimulus2.11e-011.00e+002.087111121
GO:0000122negative regulation of transcription from RNA polymerase II promoter2.22e-011.00e+001.173229456
GO:0000398mRNA splicing, via spliceosome2.22e-011.00e+002.005115128
GO:0044212transcription regulatory region DNA binding2.45e-011.00e+001.846113143
GO:0001701in utero embryonic development2.61e-011.00e+001.73917154
GO:0046872metal ion binding2.71e-011.00e+000.723324934
GO:0005874microtubule2.74e-011.00e+001.657110163
GO:0016071mRNA metabolic process2.84e-011.00e+001.596110170
GO:0006412translation2.95e-011.00e+001.530112178
GO:0004842ubiquitin-protein transferase activity2.97e-011.00e+001.522117179
GO:0016070RNA metabolic process3.09e-011.00e+001.451110188
GO:0005743mitochondrial inner membrane3.21e-011.00e+001.38319197
GO:0004674protein serine/threonine kinase activity3.21e-011.00e+001.38318197
GO:0015031protein transport3.29e-011.00e+001.340110203
GO:0006357regulation of transcription from RNA polymerase II promoter3.29e-011.00e+001.340114203
GO:0019899enzyme binding3.39e-011.00e+001.29117210
GO:0005813centrosome3.48e-011.00e+001.244110217
GO:0007155cell adhesion3.82e-011.00e+001.07518244
GO:0003682chromatin binding3.92e-011.00e+001.028115252
GO:0006355regulation of transcription, DNA-templated4.10e-011.00e+000.524231715
GO:0008285negative regulation of cell proliferation4.21e-011.00e+000.892111277
GO:0005925focal adhesion4.27e-011.00e+000.866114282
GO:0055114oxidation-reduction process4.56e-011.00e+000.73919308
GO:0045892negative regulation of transcription, DNA-templated4.66e-011.00e+000.697117317
GO:0006366transcription from RNA polymerase II promoter4.91e-011.00e+000.592123341
GO:0042802identical protein binding5.05e-011.00e+000.538115354
GO:0045893positive regulation of transcription, DNA-templated5.27e-011.00e+000.447121377
GO:0003677DNA binding5.62e-011.00e+000.118252947
GO:0042803protein homodimerization activity5.74e-011.00e+000.264113428
GO:0005887integral component of plasma membrane6.85e-011.00e+00-0.16218575
GO:0007165signal transduction7.12e-011.00e+00-0.266124618
GO:0005615extracellular space7.31e-011.00e+00-0.341115651
GO:0008270zinc ion binding7.70e-011.00e+00-0.500139727
GO:0070062extracellular vesicular exosome8.54e-011.00e+00-0.6752511641
GO:0005886plasma membrane9.78e-011.00e+00-1.7951461784