reg-snw-81608

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.459 1.13e-08 7.59e-03 6.82e-03
chia-screen-data-Fav-reg-snw-81608 subnetwork

Genes (12)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
NDUFA4L2 56901 44-2.4772.45921-Yes-
EIF2S2 8894 40-2.9992.45922-YesYes
NCBP1 4686 41-2.5102.45944-YesYes
PHB 5245 82-2.7432.68936-YesYes
VARS 7407 60-2.3662.689124TFYes-
CENPQ 55166 20-2.1372.45916-Yes-
CCT7 10574 40-2.3352.45938-Yes-
[ FIP1L1 ] 81608 2-1.6262.45931---
GPS1 2873 86-3.6212.68936TFYesYes
POLH 5429 36-2.5862.45924-YesYes
CLASP1 23332 10-2.3652.45939TFYes-
FBXO22 26263 36-1.7392.459208TF--

Interactions (12)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
VARS 7407 FBXO22 26263 pd <> reg.ITFP.txt: no annot
PHB 5245 VARS 7407 pd < reg.ITFP.txt: no annot
PHB 5245 FBXO22 26263 pd < reg.ITFP.txt: no annot
POLH 5429 FBXO22 26263 pd < reg.ITFP.txt: no annot
FBXO22 26263 FIP1L1 81608 pd > reg.ITFP.txt: no annot
FBXO22 26263 CENPQ 55166 pd > reg.ITFP.txt: no annot
NCBP1 4686 FBXO22 26263 pd < reg.ITFP.txt: no annot
CLASP1 23332 FIP1L1 81608 pd > reg.ITFP.txt: no annot
EIF2S2 8894 FBXO22 26263 pd < reg.ITFP.txt: no annot
FBXO22 26263 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot
CCT7 10574 FBXO22 26263 pd < reg.ITFP.txt: no annot

Related GO terms (142)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0004832valine-tRNA ligase activity1.23e-031.00e+009.668111
GO:0031592centrosomal corona1.23e-031.00e+009.668111
GO:0006438valyl-tRNA aminoacylation1.23e-031.00e+009.668111
GO:0031111negative regulation of microtubule polymerization or depolymerization2.46e-031.00e+008.668112
GO:0048742regulation of skeletal muscle fiber development2.46e-031.00e+008.668112
GO:0030981cortical microtubule cytoskeleton2.46e-031.00e+008.668112
GO:0005846nuclear cap binding complex2.46e-031.00e+008.668112
GO:0002176male germ cell proliferation2.46e-031.00e+008.668112
GO:0051294establishment of spindle orientation2.46e-031.00e+008.668112
GO:0005850eukaryotic translation initiation factor 2 complex3.68e-031.00e+008.083123
GO:0045292mRNA cis splicing, via spliceosome4.91e-031.00e+007.668114
GO:0031442positive regulation of mRNA 3'-end processing4.91e-031.00e+007.668114
GO:0006290pyrimidine dimer repair4.91e-031.00e+007.668124
GO:0043515kinetochore binding4.91e-031.00e+007.668124
GO:0010458exit from mitosis6.13e-031.00e+007.347125
GO:0005828kinetochore microtubule6.13e-031.00e+007.347115
GO:0006282regulation of DNA repair6.13e-031.00e+007.347125
GO:2000323negative regulation of glucocorticoid receptor signaling pathway6.13e-031.00e+007.347115
GO:0002161aminoacyl-tRNA editing activity6.13e-031.00e+007.347115
GO:0031023microtubule organizing center organization6.13e-031.00e+007.347115
GO:0005739mitochondrion6.57e-031.00e+002.304432659
GO:0050847progesterone receptor signaling pathway7.35e-031.00e+007.083126
GO:0002199zona pellucida receptor complex8.57e-031.00e+006.861147
GO:0000731DNA synthesis involved in DNA repair8.57e-031.00e+006.861117
GO:0006301postreplication repair8.57e-031.00e+006.861127
GO:0000339RNA cap binding8.57e-031.00e+006.861117
GO:0005832chaperonin-containing T-complex8.57e-031.00e+006.861147
GO:0005845mRNA cap binding complex9.79e-031.00e+006.668118
GO:0006450regulation of translational fidelity9.79e-031.00e+006.668118
GO:0010944negative regulation of transcription by competitive promoter binding9.79e-031.00e+006.668118
GO:0010388cullin deneddylation9.79e-031.00e+006.668148
GO:0034453microtubule anchoring1.10e-021.00e+006.499119
GO:0010225response to UV-C1.10e-021.00e+006.499129
GO:0006379mRNA cleavage1.10e-021.00e+006.499129
GO:0071354cellular response to interleukin-61.10e-021.00e+006.499119
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process1.10e-021.00e+006.499129
GO:0005847mRNA cleavage and polyadenylation specificity factor complex1.10e-021.00e+006.499139
GO:0005095GTPase inhibitor activity1.22e-021.00e+006.3471110
GO:0001578microtubule bundle formation1.22e-021.00e+006.3471210
GO:0005829cytosol1.26e-021.00e+001.4506881787
GO:0060766negative regulation of androgen receptor signaling pathway1.34e-021.00e+006.2091411
GO:0051010microtubule plus-end binding1.34e-021.00e+006.2091211
GO:0007026negative regulation of microtubule depolymerization1.34e-021.00e+006.2091211
GO:0007020microtubule nucleation1.34e-021.00e+006.2091111
GO:0008334histone mRNA metabolic process1.34e-021.00e+006.2091111
GO:0016575histone deacetylation1.71e-021.00e+005.8611214
GO:0005654nucleoplasm1.77e-021.00e+001.894468876
GO:0008135translation factor activity, nucleic acid binding1.83e-021.00e+005.7621415
GO:0000188inactivation of MAPK activity1.83e-021.00e+005.7621115
GO:0007339binding of sperm to zona pellucida1.83e-021.00e+005.7621415
GO:0003887DNA-directed DNA polymerase activity1.95e-021.00e+005.6681216
GO:0031047gene silencing by RNA2.19e-021.00e+005.4991218
GO:0007163establishment or maintenance of cell polarity2.43e-021.00e+005.3471120
GO:0006913nucleocytoplasmic transport2.43e-021.00e+005.3471220
GO:0034080CENP-A containing nucleosome assembly2.43e-021.00e+005.3471220
GO:0071897DNA biosynthetic process2.43e-021.00e+005.3471220
GO:0034660ncRNA metabolic process2.43e-021.00e+005.3471120
GO:0010467gene expression2.48e-021.00e+002.190349535
GO:0051084'de novo' posttranslational protein folding2.67e-021.00e+005.2091422
GO:0000387spliceosomal snRNP assembly2.67e-021.00e+005.2091122
GO:0005881cytoplasmic microtubule2.91e-021.00e+005.0831324
GO:00063707-methylguanosine mRNA capping2.91e-021.00e+005.0831524
GO:0008180COP9 signalosome2.91e-021.00e+005.0831624
GO:0005876spindle microtubule2.91e-021.00e+005.0831424
GO:0009267cellular response to starvation3.15e-021.00e+004.9681126
GO:0006418tRNA aminoacylation for protein translation3.51e-021.00e+004.8101429
GO:0006446regulation of translational initiation3.51e-021.00e+004.8101229
GO:0003723RNA binding3.56e-021.00e+002.720222247
GO:0045111intermediate filament cytoskeleton3.75e-021.00e+004.7141331
GO:0007254JNK cascade4.10e-021.00e+004.5811134
GO:0050434positive regulation of viral transcription4.22e-021.00e+004.5391535
GO:0031124mRNA 3'-end processing4.22e-021.00e+004.5391435
GO:0044297cell body4.22e-021.00e+004.5391535
GO:0000226microtubule cytoskeleton organization4.34e-021.00e+004.4991136
GO:0003743translation initiation factor activity4.46e-021.00e+004.4591837
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process4.57e-021.00e+004.4211438
GO:0006369termination of RNA polymerase II transcription4.57e-021.00e+004.4211538
GO:0000775chromosome, centromeric region4.93e-021.00e+004.3111641
GO:0003684damaged DNA binding4.93e-021.00e+004.3111141
GO:0006406mRNA export from nucleus5.28e-021.00e+004.2091744
GO:0000278mitotic cell cycle5.50e-021.00e+002.374228314
GO:0051301cell division5.86e-021.00e+004.0541249
GO:0006334nucleosome assembly6.09e-021.00e+003.9961451
GO:0006368transcription elongation from RNA polymerase II promoter6.21e-021.00e+003.9681852
GO:0000776kinetochore6.56e-021.00e+003.8871855
GO:0044267cellular protein metabolic process6.74e-021.00e+002.209214352
GO:0008584male gonad development6.79e-021.00e+003.8361157
GO:0000777condensed chromosome kinetochore6.79e-021.00e+003.8361657
GO:0044822poly(A) RNA binding6.88e-021.00e+001.611345799
GO:0042826histone deacetylase binding6.90e-021.00e+003.8101558
GO:0006464cellular protein modification process7.25e-021.00e+003.7381461
GO:0030018Z disc7.59e-021.00e+003.6681364
GO:0030308negative regulation of cell growth8.28e-021.00e+003.5391370
GO:0051082unfolded protein binding8.28e-021.00e+003.5391570
GO:0001649osteoblast differentiation8.73e-021.00e+003.4591574
GO:0005938cell cortex9.07e-021.00e+003.4021677
GO:0030529ribonucleoprotein complex9.63e-021.00e+003.3111582
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay9.85e-021.00e+003.2761584
GO:0000209protein polyubiquitination1.07e-011.00e+003.1451692
GO:0006511ubiquitin-dependent protein catabolic process1.07e-011.00e+003.1451692
GO:0006260DNA replication1.10e-011.00e+003.1141994
GO:0000086G2/M transition of mitotic cell cycle1.13e-011.00e+003.0691797
GO:0008017microtubule binding1.13e-011.00e+003.0691997
GO:0006457protein folding1.13e-011.00e+003.0691597
GO:0006413translational initiation1.15e-011.00e+003.0391699
GO:0006397mRNA processing1.27e-011.00e+002.887112110
GO:0042981regulation of apoptotic process1.29e-011.00e+002.86114112
GO:0007049cell cycle1.33e-011.00e+002.82318115
GO:0000398mRNA splicing, via spliceosome1.47e-011.00e+002.668115128
GO:0044212transcription regulatory region DNA binding1.62e-011.00e+002.509113143
GO:0001701in utero embryonic development1.74e-011.00e+002.40217154
GO:0005634nucleus1.76e-011.00e+000.58961583246
GO:0005730nucleolus1.81e-011.00e+001.0043741217
GO:0005874microtubule1.83e-011.00e+002.320110163
GO:0008380RNA splicing1.85e-011.00e+002.302121165
GO:0016071mRNA metabolic process1.90e-011.00e+002.259110170
GO:0006412translation1.98e-011.00e+002.193112178
GO:0004842ubiquitin-protein transferase activity1.99e-011.00e+002.185117179
GO:0005515protein binding2.00e-011.00e+000.46671984124
GO:0005737cytoplasm2.01e-011.00e+000.62851272633
GO:0016070RNA metabolic process2.08e-011.00e+002.114110188
GO:0005743mitochondrial inner membrane2.17e-011.00e+002.04619197
GO:0006281DNA repair2.23e-011.00e+002.003124203
GO:0019899enzyme binding2.30e-011.00e+001.95417210
GO:0005813centrosome2.36e-011.00e+001.907110217
GO:0007411axon guidance2.55e-011.00e+001.78018237
GO:0008285negative regulation of cell proliferation2.92e-011.00e+001.555111277
GO:0005524ATP binding3.01e-011.00e+000.868237892
GO:0046872metal ion binding3.21e-011.00e+000.801224934
GO:0070062extracellular vesicular exosome3.27e-011.00e+000.5733511641
GO:0045892negative regulation of transcription, DNA-templated3.27e-011.00e+001.360117317
GO:0006366transcription from RNA polymerase II promoter3.47e-011.00e+001.255123341
GO:0042802identical protein binding3.58e-011.00e+001.201115354
GO:0045893positive regulation of transcription, DNA-templated3.77e-011.00e+001.110121377
GO:0005794Golgi apparatus4.06e-011.00e+000.97116415
GO:0016032viral process4.16e-011.00e+000.927130428
GO:0000122negative regulation of transcription from RNA polymerase II promoter4.37e-011.00e+000.836129456
GO:0016020membrane4.47e-011.00e+000.4312561207
GO:0005887integral component of plasma membrane5.17e-011.00e+000.50118575
GO:0007165signal transduction5.44e-011.00e+000.397124618
GO:0006355regulation of transcription, DNA-templated5.99e-011.00e+000.187131715
GO:0005886plasma membrane9.11e-011.00e+00-1.1321461784