reg-snw-7596

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.279	1.11e-07	2.83e-02	2.21e-02

chia-screen-data-Fav-reg-snw-7596 subnetwork

Genes (16)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
NDUFA4L2	56901	44	-2.477	2.459	21	-	Yes	-
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
VARS	7407	60	-2.366	2.689	124	TF	Yes	-
KLHL8	57563	4	-1.993	2.308	30	TF	-	-
FBXO22	26263	36	-1.739	2.459	208	TF	-	-
PAPOLA	10914	9	-1.996	2.455	19	-	-	-
NCBP1	4686	41	-2.510	2.459	44	-	Yes	Yes
EIF2S2	8894	40	-2.999	2.459	22	-	Yes	Yes
CENPQ	55166	20	-2.137	2.459	16	-	Yes	-
CCT7	10574	40	-2.335	2.459	38	-	Yes	-
FIP1L1	81608	2	-1.626	2.459	31	-	-	-
[ ZNF45 ]	7596	1	-0.915	2.279	4	TF	-	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
POLH	5429	36	-2.586	2.459	24	-	Yes	Yes
CLASP1	23332	10	-2.365	2.459	39	TF	Yes	-
PSPH	5723	14	-2.063	2.387	11	-	Yes	-

Interactions (16)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
VARS	7407	FBXO22	26263	pd	<>	reg.ITFP.txt: no annot
PHB	5245	VARS	7407	pd	<	reg.ITFP.txt: no annot
PAPOLA	10914	CLASP1	23332	pd	<	reg.ITFP.txt: no annot
PHB	5245	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
POLH	5429	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
FBXO22	26263	FIP1L1	81608	pd	>	reg.ITFP.txt: no annot
FBXO22	26263	CENPQ	55166	pd	>	reg.ITFP.txt: no annot
NCBP1	4686	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
CLASP1	23332	FIP1L1	81608	pd	>	reg.ITFP.txt: no annot
EIF2S2	8894	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
PSPH	5723	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
FBXO22	26263	NDUFA4L2	56901	pd	>	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
CCT7	10574	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
CLASP1	23332	KLHL8	57563	pd	<>	reg.ITFP.txt: no annot
ZNF45	7596	FIP1L1	81608	pd	>	reg.ITFP.txt: no annot

Related GO terms (166)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0010467	gene expression	1.28e-03	1.00e+00	2.512	5	49	535
GO:0031124	mRNA 3'-end processing	1.45e-03	1.00e+00	5.124	2	4	35
GO:0004832	valine-tRNA ligase activity	1.64e-03	1.00e+00	9.253	1	1	1
GO:0031592	centrosomal corona	1.64e-03	1.00e+00	9.253	1	1	1
GO:0006438	valyl-tRNA aminoacylation	1.64e-03	1.00e+00	9.253	1	1	1
GO:0006369	termination of RNA polymerase II transcription	1.71e-03	1.00e+00	5.005	2	5	38
GO:0005654	nucleoplasm	1.87e-03	1.00e+00	2.064	6	68	876
GO:0031111	negative regulation of microtubule polymerization or depolymerization	3.27e-03	1.00e+00	8.253	1	1	2
GO:0048742	regulation of skeletal muscle fiber development	3.27e-03	1.00e+00	8.253	1	1	2
GO:0030981	cortical microtubule cytoskeleton	3.27e-03	1.00e+00	8.253	1	1	2
GO:0004647	phosphoserine phosphatase activity	3.27e-03	1.00e+00	8.253	1	1	2
GO:0005846	nuclear cap binding complex	3.27e-03	1.00e+00	8.253	1	1	2
GO:0002176	male germ cell proliferation	3.27e-03	1.00e+00	8.253	1	1	2
GO:0051294	establishment of spindle orientation	3.27e-03	1.00e+00	8.253	1	1	2
GO:0005850	eukaryotic translation initiation factor 2 complex	4.91e-03	1.00e+00	7.668	1	2	3
GO:0006563	L-serine metabolic process	4.91e-03	1.00e+00	7.668	1	1	3
GO:0045292	mRNA cis splicing, via spliceosome	6.54e-03	1.00e+00	7.253	1	1	4
GO:0004652	polynucleotide adenylyltransferase activity	6.54e-03	1.00e+00	7.253	1	1	4
GO:0031442	positive regulation of mRNA 3'-end processing	6.54e-03	1.00e+00	7.253	1	1	4
GO:0006290	pyrimidine dimer repair	6.54e-03	1.00e+00	7.253	1	2	4
GO:0043631	RNA polyadenylation	6.54e-03	1.00e+00	7.253	1	1	4
GO:0006564	L-serine biosynthetic process	6.54e-03	1.00e+00	7.253	1	1	4
GO:0043515	kinetochore binding	6.54e-03	1.00e+00	7.253	1	2	4
GO:0003723	RNA binding	7.02e-03	1.00e+00	2.890	3	22	247
GO:0010458	exit from mitosis	8.17e-03	1.00e+00	6.931	1	2	5
GO:0005828	kinetochore microtubule	8.17e-03	1.00e+00	6.931	1	1	5
GO:0006282	regulation of DNA repair	8.17e-03	1.00e+00	6.931	1	2	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	8.17e-03	1.00e+00	6.931	1	1	5
GO:0002161	aminoacyl-tRNA editing activity	8.17e-03	1.00e+00	6.931	1	1	5
GO:0031023	microtubule organizing center organization	8.17e-03	1.00e+00	6.931	1	1	5
GO:0050847	progesterone receptor signaling pathway	9.79e-03	1.00e+00	6.668	1	2	6
GO:0002199	zona pellucida receptor complex	1.14e-02	1.00e+00	6.446	1	4	7
GO:0000731	DNA synthesis involved in DNA repair	1.14e-02	1.00e+00	6.446	1	1	7
GO:0006301	postreplication repair	1.14e-02	1.00e+00	6.446	1	2	7
GO:0000339	RNA cap binding	1.14e-02	1.00e+00	6.446	1	1	7
GO:0005832	chaperonin-containing T-complex	1.14e-02	1.00e+00	6.446	1	4	7
GO:0005845	mRNA cap binding complex	1.30e-02	1.00e+00	6.253	1	1	8
GO:0006450	regulation of translational fidelity	1.30e-02	1.00e+00	6.253	1	1	8
GO:0010944	negative regulation of transcription by competitive promoter binding	1.30e-02	1.00e+00	6.253	1	1	8
GO:0010388	cullin deneddylation	1.30e-02	1.00e+00	6.253	1	4	8
GO:0034453	microtubule anchoring	1.47e-02	1.00e+00	6.083	1	1	9
GO:0010225	response to UV-C	1.47e-02	1.00e+00	6.083	1	2	9
GO:0006379	mRNA cleavage	1.47e-02	1.00e+00	6.083	1	2	9
GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.47e-02	1.00e+00	6.083	1	2	9
GO:0071354	cellular response to interleukin-6	1.47e-02	1.00e+00	6.083	1	1	9
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	1.47e-02	1.00e+00	6.083	1	3	9
GO:0000287	magnesium ion binding	1.48e-02	1.00e+00	3.408	2	4	115
GO:0005095	GTPase inhibitor activity	1.63e-02	1.00e+00	5.931	1	1	10
GO:0001578	microtubule bundle formation	1.63e-02	1.00e+00	5.931	1	2	10
GO:0005829	cytosol	1.66e-02	1.00e+00	1.257	7	88	1787
GO:0060766	negative regulation of androgen receptor signaling pathway	1.79e-02	1.00e+00	5.794	1	4	11
GO:0051010	microtubule plus-end binding	1.79e-02	1.00e+00	5.794	1	2	11
GO:0007026	negative regulation of microtubule depolymerization	1.79e-02	1.00e+00	5.794	1	2	11
GO:0007020	microtubule nucleation	1.79e-02	1.00e+00	5.794	1	1	11
GO:0008652	cellular amino acid biosynthetic process	1.79e-02	1.00e+00	5.794	1	2	11
GO:0008334	histone mRNA metabolic process	1.79e-02	1.00e+00	5.794	1	1	11
GO:0000398	mRNA splicing, via spliceosome	1.81e-02	1.00e+00	3.253	2	15	128
GO:0005739	mitochondrion	1.95e-02	1.00e+00	1.889	4	32	659
GO:0016575	histone deacetylation	2.27e-02	1.00e+00	5.446	1	2	14
GO:0008135	translation factor activity, nucleic acid binding	2.43e-02	1.00e+00	5.347	1	4	15
GO:0000188	inactivation of MAPK activity	2.43e-02	1.00e+00	5.347	1	1	15
GO:0007339	binding of sperm to zona pellucida	2.43e-02	1.00e+00	5.347	1	4	15
GO:0031463	Cul3-RING ubiquitin ligase complex	2.59e-02	1.00e+00	5.253	1	1	16
GO:0003887	DNA-directed DNA polymerase activity	2.59e-02	1.00e+00	5.253	1	2	16
GO:0031667	response to nutrient levels	2.75e-02	1.00e+00	5.166	1	2	17
GO:0031047	gene silencing by RNA	2.91e-02	1.00e+00	5.083	1	2	18
GO:0033574	response to testosterone	2.91e-02	1.00e+00	5.083	1	1	18
GO:0008380	RNA splicing	2.92e-02	1.00e+00	2.887	2	21	165
GO:0007163	establishment or maintenance of cell polarity	3.23e-02	1.00e+00	4.931	1	1	20
GO:0006913	nucleocytoplasmic transport	3.23e-02	1.00e+00	4.931	1	2	20
GO:0034080	CENP-A containing nucleosome assembly	3.23e-02	1.00e+00	4.931	1	2	20
GO:0071897	DNA biosynthetic process	3.23e-02	1.00e+00	4.931	1	2	20
GO:0034660	ncRNA metabolic process	3.23e-02	1.00e+00	4.931	1	1	20
GO:0051084	'de novo' posttranslational protein folding	3.55e-02	1.00e+00	4.794	1	4	22
GO:0000387	spliceosomal snRNP assembly	3.55e-02	1.00e+00	4.794	1	1	22
GO:0005881	cytoplasmic microtubule	3.86e-02	1.00e+00	4.668	1	3	24
GO:0006370	7-methylguanosine mRNA capping	3.86e-02	1.00e+00	4.668	1	5	24
GO:0008180	COP9 signalosome	3.86e-02	1.00e+00	4.668	1	6	24
GO:0005876	spindle microtubule	3.86e-02	1.00e+00	4.668	1	4	24
GO:0005730	nucleolus	4.01e-02	1.00e+00	1.326	5	74	1217
GO:0030145	manganese ion binding	4.18e-02	1.00e+00	4.553	1	3	26
GO:0009267	cellular response to starvation	4.18e-02	1.00e+00	4.553	1	1	26
GO:0006418	tRNA aminoacylation for protein translation	4.65e-02	1.00e+00	4.395	1	4	29
GO:0006446	regulation of translational initiation	4.65e-02	1.00e+00	4.395	1	2	29
GO:0045111	intermediate filament cytoskeleton	4.96e-02	1.00e+00	4.299	1	3	31
GO:0007254	JNK cascade	5.43e-02	1.00e+00	4.166	1	1	34
GO:0050434	positive regulation of viral transcription	5.59e-02	1.00e+00	4.124	1	5	35
GO:0044297	cell body	5.59e-02	1.00e+00	4.124	1	5	35
GO:0000226	microtubule cytoskeleton organization	5.74e-02	1.00e+00	4.083	1	1	36
GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	5.90e-02	1.00e+00	4.044	1	2	37
GO:0003743	translation initiation factor activity	5.90e-02	1.00e+00	4.044	1	8	37
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	6.05e-02	1.00e+00	4.005	1	4	38
GO:0000775	chromosome, centromeric region	6.52e-02	1.00e+00	3.896	1	6	41
GO:0003684	damaged DNA binding	6.52e-02	1.00e+00	3.896	1	1	41
GO:0006406	mRNA export from nucleus	6.98e-02	1.00e+00	3.794	1	7	44
GO:0009612	response to mechanical stimulus	7.28e-02	1.00e+00	3.730	1	2	46
GO:0051301	cell division	7.74e-02	1.00e+00	3.639	1	2	49
GO:0006334	nucleosome assembly	8.04e-02	1.00e+00	3.581	1	4	51
GO:0006368	transcription elongation from RNA polymerase II promoter	8.19e-02	1.00e+00	3.553	1	8	52
GO:0000776	kinetochore	8.65e-02	1.00e+00	3.472	1	8	55
GO:0016311	dephosphorylation	8.65e-02	1.00e+00	3.472	1	3	55
GO:0008584	male gonad development	8.95e-02	1.00e+00	3.421	1	1	57
GO:0000777	condensed chromosome kinetochore	8.95e-02	1.00e+00	3.421	1	6	57
GO:0042826	histone deacetylase binding	9.10e-02	1.00e+00	3.395	1	5	58
GO:0000278	mitotic cell cycle	9.20e-02	1.00e+00	1.959	2	28	314
GO:0006464	cellular protein modification process	9.55e-02	1.00e+00	3.323	1	4	61
GO:0030018	Z disc	9.99e-02	1.00e+00	3.253	1	3	64
GO:0006366	transcription from RNA polymerase II promoter	1.06e-01	1.00e+00	1.840	2	23	341
GO:0030308	negative regulation of cell growth	1.09e-01	1.00e+00	3.124	1	3	70
GO:0051082	unfolded protein binding	1.09e-01	1.00e+00	3.124	1	5	70
GO:0005737	cytoplasm	1.12e-01	1.00e+00	0.698	7	127	2633
GO:0044267	cellular protein metabolic process	1.12e-01	1.00e+00	1.794	2	14	352
GO:0001649	osteoblast differentiation	1.15e-01	1.00e+00	3.044	1	5	74
GO:0005938	cell cortex	1.19e-01	1.00e+00	2.987	1	6	77
GO:0005634	nucleus	1.25e-01	1.00e+00	0.589	8	158	3246
GO:0030529	ribonucleoprotein complex	1.26e-01	1.00e+00	2.896	1	5	82
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.29e-01	1.00e+00	2.861	1	5	84
GO:0044822	poly(A) RNA binding	1.38e-01	1.00e+00	1.196	3	45	799
GO:0000209	protein polyubiquitination	1.41e-01	1.00e+00	2.730	1	6	92
GO:0006511	ubiquitin-dependent protein catabolic process	1.41e-01	1.00e+00	2.730	1	6	92
GO:0006260	DNA replication	1.43e-01	1.00e+00	2.699	1	9	94
GO:0000086	G2/M transition of mitotic cell cycle	1.48e-01	1.00e+00	2.653	1	7	97
GO:0008017	microtubule binding	1.48e-01	1.00e+00	2.653	1	9	97
GO:0006457	protein folding	1.48e-01	1.00e+00	2.653	1	5	97
GO:0006413	translational initiation	1.51e-01	1.00e+00	2.624	1	6	99
GO:0034641	cellular nitrogen compound metabolic process	1.59e-01	1.00e+00	2.539	1	5	105
GO:0006397	mRNA processing	1.66e-01	1.00e+00	2.472	1	12	110
GO:0042981	regulation of apoptotic process	1.69e-01	1.00e+00	2.446	1	4	112
GO:0043005	neuron projection	1.70e-01	1.00e+00	2.433	1	6	113
GO:0007049	cell cycle	1.73e-01	1.00e+00	2.408	1	8	115
GO:0005524	ATP binding	1.75e-01	1.00e+00	1.037	3	37	892
GO:0046872	metal ion binding	1.92e-01	1.00e+00	0.971	3	24	934
GO:0044212	transcription regulatory region DNA binding	2.10e-01	1.00e+00	2.094	1	13	143
GO:0001701	in utero embryonic development	2.25e-01	1.00e+00	1.987	1	7	154
GO:0006367	transcription initiation from RNA polymerase II promoter	2.34e-01	1.00e+00	1.922	1	18	161
GO:0005874	microtubule	2.36e-01	1.00e+00	1.905	1	10	163
GO:0016071	mRNA metabolic process	2.45e-01	1.00e+00	1.844	1	10	170
GO:0006412	translation	2.55e-01	1.00e+00	1.778	1	12	178
GO:0004842	ubiquitin-protein transferase activity	2.56e-01	1.00e+00	1.770	1	17	179
GO:0016567	protein ubiquitination	2.67e-01	1.00e+00	1.699	1	14	188
GO:0016070	RNA metabolic process	2.67e-01	1.00e+00	1.699	1	10	188
GO:0005743	mitochondrial inner membrane	2.78e-01	1.00e+00	1.631	1	9	197
GO:0006281	DNA repair	2.86e-01	1.00e+00	1.588	1	24	203
GO:0019899	enzyme binding	2.94e-01	1.00e+00	1.539	1	7	210
GO:0007275	multicellular organismal development	2.99e-01	1.00e+00	1.512	1	9	214
GO:0005813	centrosome	3.02e-01	1.00e+00	1.492	1	10	217
GO:0007411	axon guidance	3.25e-01	1.00e+00	1.365	1	8	237
GO:0006355	regulation of transcription, DNA-templated	3.29e-01	1.00e+00	0.772	2	31	715
GO:0008285	negative regulation of cell proliferation	3.69e-01	1.00e+00	1.140	1	11	277
GO:0045892	negative regulation of transcription, DNA-templated	4.10e-01	1.00e+00	0.945	1	17	317
GO:0005509	calcium ion binding	4.44e-01	1.00e+00	0.798	1	9	351
GO:0042802	identical protein binding	4.46e-01	1.00e+00	0.786	1	15	354
GO:0045893	positive regulation of transcription, DNA-templated	4.68e-01	1.00e+00	0.695	1	21	377
GO:0005794	Golgi apparatus	5.01e-01	1.00e+00	0.556	1	6	415
GO:0042803	protein homodimerization activity	5.12e-01	1.00e+00	0.512	1	13	428
GO:0016032	viral process	5.12e-01	1.00e+00	0.512	1	30	428
GO:0070062	extracellular vesicular exosome	5.19e-01	1.00e+00	0.158	3	51	1641
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	5.35e-01	1.00e+00	0.421	1	29	456
GO:0005515	protein binding	5.46e-01	1.00e+00	0.051	7	198	4124
GO:0016020	membrane	6.06e-01	1.00e+00	0.016	2	56	1207
GO:0005887	integral component of plasma membrane	6.22e-01	1.00e+00	0.086	1	8	575
GO:0003700	sequence-specific DNA binding transcription factor activity	6.26e-01	1.00e+00	0.069	1	22	582
GO:0007165	signal transduction	6.49e-01	1.00e+00	-0.018	1	24	618
GO:0044281	small molecule metabolic process	7.65e-01	1.00e+00	-0.468	1	35	844
GO:0003677	DNA binding	8.05e-01	1.00e+00	-0.634	1	52	947
GO:0005886	plasma membrane	9.60e-01	1.00e+00	-1.547	1	46	1784

chia-Fav

reg-snw-7596

Statistics

Genes (16)

Interactions (16)

Related GO terms (166)