reg-snw-6595

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.241 1.78e-07 3.64e-02 2.79e-02
chia-screen-data-Fav-reg-snw-6595 subnetwork

Genes (15)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
APLP2 334 15-2.7322.3894-YesYes
[ SMARCA2 ] 6595 1-1.1092.24121TF--
RHOA 387 17-2.4082.64410-YesYes
EPS15 2060 1-1.9122.2419---
PHB 5245 82-2.7432.68936-YesYes
FTSJ1 24140 43-2.4632.68935-YesYes
POLR2E 5434 30-2.0372.644201TFYes-
VARS 7407 60-2.3662.689124TFYes-
FUS 2521 11-1.9802.41453TF--
UBE2S 27338 3-1.3822.34258---
HNRNPU 3192 39-2.8692.64433-Yes-
LDB2 9079 1-2.3802.2416-Yes-
GPS1 2873 86-3.6212.68936TFYesYes
AP2S1 1175 5-1.5582.36739---
SFPQ 6421 15-2.0512.389142TFYes-

Interactions (19)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
FUS 2521 POLR2E 5434 pd <> reg.ITFP.txt: no annot
SFPQ 6421 UBE2S 27338 pd > reg.ITFP.txt: no annot
VARS 7407 FTSJ1 24140 pd > reg.ITFP.txt: no annot
PHB 5245 VARS 7407 pd < reg.ITFP.txt: no annot
POLR2E 5434 FTSJ1 24140 pd > reg.ITFP.txt: no annot
POLR2E 5434 VARS 7407 pd <> reg.ITFP.txt: no annot
FUS 2521 UBE2S 27338 pd > reg.ITFP.txt: no annot
SMARCA2 6595 LDB2 9079 pd > reg.ITFP.txt: no annot
APLP2 334 SFPQ 6421 pd < reg.ITFP.txt: no annot
FUS 2521 HNRNPU 3192 pd > reg.ITFP.txt: no annot
HNRNPU 3192 POLR2E 5434 pd < reg.ITFP.txt: no annot
AP2S1 1175 POLR2E 5434 pd < reg.ITFP.txt: no annot
AP2S1 1175 SMARCA2 6595 pd < reg.ITFP.txt: no annot
RHOA 387 POLR2E 5434 pd < reg.ITFP.txt: no annot
VARS 7407 UBE2S 27338 pd > reg.ITFP.txt: no annot
AP2S1 1175 VARS 7407 pd < reg.ITFP.txt: no annot
SMARCA2 6595 UBE2S 27338 pd > reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot
EPS15 2060 SMARCA2 6595 pd < reg.ITFP.txt: no annot

Related GO terms (219)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0030122AP-2 adaptor complex7.88e-057.69e-017.177229
GO:0048268clathrin coat assembly7.88e-057.69e-017.177229
GO:0008380RNA splicing9.28e-059.06e-013.980421165
GO:0042059negative regulation of epidermal growth factor receptor signaling pathway8.14e-041.00e+005.5392228
GO:0000398mRNA splicing, via spliceosome8.92e-041.00e+003.931315128
GO:0044212transcription regulatory region DNA binding1.23e-031.00e+003.772313143
GO:0005654nucleoplasm1.26e-031.00e+002.157668876
GO:0004832valine-tRNA ligase activity1.54e-031.00e+009.347111
GO:0061383trabecula morphogenesis1.54e-031.00e+009.347111
GO:0002128tRNA nucleoside ribose methylation1.54e-031.00e+009.347111
GO:0008175tRNA methyltransferase activity1.54e-031.00e+009.347111
GO:0006438valyl-tRNA aminoacylation1.54e-031.00e+009.347111
GO:0044089positive regulation of cellular component biogenesis1.54e-031.00e+009.347111
GO:0010994free ubiquitin chain polymerization3.07e-031.00e+008.347112
GO:0033688regulation of osteoblast proliferation3.07e-031.00e+008.347112
GO:0035887aortic smooth muscle cell differentiation3.07e-031.00e+008.347122
GO:0042826histone deacetylase binding3.46e-031.00e+004.4892558
GO:1902177positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway4.60e-031.00e+007.762113
GO:0046914transition metal ion binding4.60e-031.00e+007.762113
GO:0010669epithelial structure maintenance4.60e-031.00e+007.762113
GO:0030308negative regulation of cell growth5.01e-031.00e+004.2172370
GO:0001649osteoblast differentiation5.58e-031.00e+004.1372574
GO:0036089cleavage furrow formation6.13e-031.00e+007.347114
GO:0007176regulation of epidermal growth factor-activated receptor activity6.13e-031.00e+007.347114
GO:0010467gene expression7.49e-031.00e+002.283449535
GO:0030274LIM domain binding7.66e-031.00e+007.025115
GO:0010458exit from mitosis7.66e-031.00e+007.025125
GO:0035519protein K29-linked ubiquitination7.66e-031.00e+007.025125
GO:0038027apolipoprotein A-I-mediated signaling pathway7.66e-031.00e+007.025115
GO:0070934CRD-mediated mRNA stabilization7.66e-031.00e+007.025125
GO:0043931ossification involved in bone maturation7.66e-031.00e+007.025115
GO:2000323negative regulation of glucocorticoid receptor signaling pathway7.66e-031.00e+007.025115
GO:0044314protein K27-linked ubiquitination7.66e-031.00e+007.025125
GO:0002161aminoacyl-tRNA editing activity7.66e-031.00e+007.025115
GO:0051488activation of anaphase-promoting complex activity7.66e-031.00e+007.025115
GO:0042382paraspeckles7.66e-031.00e+007.025135
GO:0050847progesterone receptor signaling pathway9.18e-031.00e+006.762126
GO:0002181cytoplasmic translation9.18e-031.00e+006.762116
GO:0001055RNA polymerase II activity9.18e-031.00e+006.762136
GO:0042754negative regulation of circadian rhythm9.18e-031.00e+006.762126
GO:0085020protein K6-linked ubiquitination9.18e-031.00e+006.762126
GO:0043297apical junction assembly9.18e-031.00e+006.762116
GO:0070937CRD-mediated mRNA stability complex9.18e-031.00e+006.762126
GO:0006895Golgi to endosome transport1.07e-021.00e+006.539117
GO:0035615clathrin adaptor activity1.07e-021.00e+006.539117
GO:0007617mating behavior1.07e-021.00e+006.539117
GO:0000380alternative mRNA splicing, via spliceosome1.07e-021.00e+006.539127
GO:0045892negative regulation of transcription, DNA-templated1.15e-021.00e+002.623317317
GO:0006878cellular copper ion homeostasis1.22e-021.00e+006.347118
GO:0090307spindle assembly involved in mitosis1.22e-021.00e+006.347128
GO:0006450regulation of translational fidelity1.22e-021.00e+006.347118
GO:0010944negative regulation of transcription by competitive promoter binding1.22e-021.00e+006.347118
GO:0010388cullin deneddylation1.22e-021.00e+006.347148
GO:0043296apical junction complex1.22e-021.00e+006.347118
GO:0032456endocytic recycling1.22e-021.00e+006.347128
GO:0071354cellular response to interleukin-61.37e-021.00e+006.177119
GO:0030100regulation of endocytosis1.37e-021.00e+006.177119
GO:0072583clathrin-mediated endocytosis1.37e-021.00e+006.177119
GO:0016050vesicle organization1.37e-021.00e+006.177119
GO:0001967suckling behavior1.53e-021.00e+006.0251410
GO:0005736DNA-directed RNA polymerase I complex1.53e-021.00e+006.0251410
GO:0005095GTPase inhibitor activity1.53e-021.00e+006.0251110
GO:0071564npBAF complex1.53e-021.00e+006.0251310
GO:0050919negative chemotaxis1.53e-021.00e+006.0251110
GO:0001054RNA polymerase I activity1.53e-021.00e+006.0251410
GO:0042802identical protein binding1.55e-021.00e+002.464315354
GO:0060766negative regulation of androgen receptor signaling pathway1.68e-021.00e+005.8871411
GO:0071565nBAF complex1.68e-021.00e+005.8871311
GO:0007173epidermal growth factor receptor signaling pathway1.95e-021.00e+003.19725142
GO:0016514SWI/SNF complex1.98e-021.00e+005.6461313
GO:0050772positive regulation of axonogenesis1.98e-021.00e+005.6461213
GO:0005680anaphase-promoting complex1.98e-021.00e+005.6461213
GO:0050770regulation of axonogenesis1.98e-021.00e+005.6461313
GO:0005666DNA-directed RNA polymerase III complex1.98e-021.00e+005.6461313
GO:0005665DNA-directed RNA polymerase II, core complex1.98e-021.00e+005.6461313
GO:0001056RNA polymerase III activity1.98e-021.00e+005.6461313
GO:0042346positive regulation of NF-kappaB import into nucleus1.98e-021.00e+005.6461113
GO:0006386termination of RNA polymerase III transcription2.13e-021.00e+005.5391314
GO:0006385transcription elongation from RNA polymerase III promoter2.13e-021.00e+005.5391314
GO:0050771negative regulation of axonogenesis2.13e-021.00e+005.5391214
GO:0043393regulation of protein binding2.13e-021.00e+005.5391214
GO:0016575histone deacetylation2.13e-021.00e+005.5391214
GO:0031593polyubiquitin binding2.28e-021.00e+005.4401115
GO:0000188inactivation of MAPK activity2.28e-021.00e+005.4401115
GO:0070932histone H3 deacetylation2.28e-021.00e+005.4401215
GO:0032467positive regulation of cytokinesis2.43e-021.00e+005.3471116
GO:0017022myosin binding2.43e-021.00e+005.3471216
GO:0016032viral process2.57e-021.00e+002.190330428
GO:0003899DNA-directed RNA polymerase activity2.73e-021.00e+005.1771318
GO:0001105RNA polymerase II transcription coactivator activity2.88e-021.00e+005.0991219
GO:0060170ciliary membrane2.88e-021.00e+005.0991119
GO:0036464cytoplasmic ribonucleoprotein granule2.88e-021.00e+005.0991119
GO:0000166nucleotide binding2.91e-021.00e+002.887213176
GO:0005634nucleus3.02e-021.00e+000.85291583246
GO:0000122negative regulation of transcription from RNA polymerase II promoter3.03e-021.00e+002.099329456
GO:0070979protein K11-linked ubiquitination3.03e-021.00e+005.0251320
GO:0071897DNA biosynthetic process3.03e-021.00e+005.0251220
GO:0001942hair follicle development3.18e-021.00e+004.9541221
GO:0050690regulation of defense response to virus by virus3.33e-021.00e+004.8871122
GO:0030669clathrin-coated endocytic vesicle membrane3.48e-021.00e+004.8231123
GO:00063707-methylguanosine mRNA capping3.63e-021.00e+004.7621524
GO:0008180COP9 signalosome3.63e-021.00e+004.7621624
GO:0070534protein K63-linked ubiquitination3.63e-021.00e+004.7621324
GO:0048011neurotrophin TRK receptor signaling pathway3.65e-021.00e+002.71028199
GO:0030901midbrain development3.77e-021.00e+004.7031125
GO:0000976transcription regulatory region sequence-specific DNA binding3.77e-021.00e+004.7031325
GO:0006281DNA repair3.78e-021.00e+002.681224203
GO:0051496positive regulation of stress fiber assembly3.92e-021.00e+004.6461226
GO:0019899enzyme binding4.02e-021.00e+002.63227210
GO:0006360transcription from RNA polymerase I promoter4.07e-021.00e+004.5921427
GO:0005524ATP binding4.17e-021.00e+001.546437892
GO:0050885neuromuscular process controlling balance4.22e-021.00e+004.5391128
GO:0016881acid-amino acid ligase activity4.22e-021.00e+004.5391328
GO:0043231intracellular membrane-bounded organelle4.30e-021.00e+002.57828218
GO:0006418tRNA aminoacylation for protein translation4.37e-021.00e+004.4891429
GO:0008094DNA-dependent ATPase activity4.37e-021.00e+004.4891629
GO:0006383transcription from RNA polymerase III promoter4.37e-021.00e+004.4891629
GO:0042752regulation of circadian rhythm4.37e-021.00e+004.4891529
GO:0032154cleavage furrow4.51e-021.00e+004.4401330
GO:0045111intermediate filament cytoskeleton4.66e-021.00e+004.3921331
GO:0035019somatic stem cell maintenance4.81e-021.00e+004.3471332
GO:0005515protein binding4.97e-021.00e+000.659101984124
GO:0007411axon guidance5.00e-021.00e+002.45828237
GO:0003677DNA binding5.04e-021.00e+001.459452947
GO:0021762substantia nigra development5.10e-021.00e+004.2591134
GO:0003712transcription cofactor activity5.10e-021.00e+004.2591334
GO:0007254JNK cascade5.10e-021.00e+004.2591134
GO:0008565protein transporter activity5.25e-021.00e+004.2171235
GO:0050434positive regulation of viral transcription5.25e-021.00e+004.2171535
GO:0007266Rho protein signal transduction5.25e-021.00e+004.2171235
GO:0030900forebrain development5.39e-021.00e+004.1771236
GO:0003723RNA binding5.39e-021.00e+002.398222247
GO:0030334regulation of cell migration5.39e-021.00e+004.1771236
GO:0030666endocytic vesicle membrane5.39e-021.00e+004.1771136
GO:0005905coated pit5.54e-021.00e+004.1371237
GO:0048511rhythmic process5.68e-021.00e+004.0991538
GO:0006396RNA processing5.98e-021.00e+004.0251440
GO:0006283transcription-coupled nucleotide-excision repair5.98e-021.00e+004.0251640
GO:0004867serine-type endopeptidase inhibitor activity6.27e-021.00e+003.9541142
GO:0004386helicase activity6.27e-021.00e+003.9541342
GO:0001047core promoter binding6.27e-021.00e+003.9541442
GO:0008285negative regulation of cell proliferation6.60e-021.00e+002.233211277
GO:0008203cholesterol metabolic process6.99e-021.00e+003.7921247
GO:0007626locomotory behavior6.99e-021.00e+003.7921147
GO:0032481positive regulation of type I interferon production7.13e-021.00e+003.7621348
GO:0006310DNA recombination7.42e-021.00e+003.7031850
GO:0006368transcription elongation from RNA polymerase II promoter7.70e-021.00e+003.6461852
GO:0006289nucleotide-excision repair7.84e-021.00e+003.6191653
GO:0045666positive regulation of neuron differentiation7.84e-021.00e+003.6191353
GO:0042393histone binding7.99e-021.00e+003.5921354
GO:0006338chromatin remodeling8.13e-021.00e+003.5651755
GO:0031901early endosome membrane8.55e-021.00e+003.4891158
GO:0000785chromatin8.70e-021.00e+003.4641659
GO:0071013catalytic step 2 spliceosome8.98e-021.00e+003.4161561
GO:0006464cellular protein modification process8.98e-021.00e+003.4161461
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II9.40e-021.00e+003.3471364
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process9.54e-021.00e+003.3241765
GO:0006897endocytosis9.82e-021.00e+003.2801267
GO:0010951negative regulation of endopeptidase activity1.04e-011.00e+003.1971271
GO:0016020membrane1.04e-011.00e+001.1094561207
GO:0030496midbody1.07e-011.00e+003.1571673
GO:0016363nuclear matrix1.07e-011.00e+003.15711073
GO:0051056regulation of small GTPase mediated signal transduction1.11e-011.00e+003.0991276
GO:0017124SH3 domain binding1.11e-011.00e+003.0991276
GO:0045893positive regulation of transcription, DNA-templated1.12e-011.00e+001.788221377
GO:0005938cell cortex1.12e-011.00e+003.0801677
GO:0030529ribonucleoprotein complex1.19e-011.00e+002.9891582
GO:0044822poly(A) RNA binding1.19e-011.00e+001.289345799
GO:0005215transporter activity1.19e-011.00e+002.9891582
GO:0048015phosphatidylinositol-mediated signaling1.20e-011.00e+002.9711283
GO:0005829cytosol1.23e-011.00e+000.8655881787
GO:0030027lamellipodium1.27e-011.00e+002.8871388
GO:0006886intracellular protein transport1.28e-011.00e+002.8711289
GO:0030036actin cytoskeleton organization1.30e-011.00e+002.8551490
GO:0008201heparin binding1.31e-011.00e+002.8391491
GO:0007179transforming growth factor beta receptor signaling pathway1.52e-011.00e+002.60515107
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling1.54e-011.00e+002.59212108
GO:0000790nuclear chromatin1.55e-011.00e+002.57819109
GO:0006397mRNA processing1.56e-011.00e+002.565112110
GO:0042981regulation of apoptotic process1.59e-011.00e+002.53914112
GO:0007049cell cycle1.63e-011.00e+002.50118115
GO:0003924GTPase activity1.68e-011.00e+002.45217119
GO:0006184GTP catabolic process1.82e-011.00e+002.32417130
GO:0005737cytoplasm1.95e-011.00e+000.56961272633
GO:0030168platelet activation1.96e-011.00e+002.20715141
GO:0005667transcription factor complex2.04e-011.00e+002.14718147
GO:0007399nervous system development2.10e-011.00e+002.09914152
GO:0006367transcription initiation from RNA polymerase II promoter2.21e-011.00e+002.016118161
GO:0007264small GTPase mediated signal transduction2.37e-011.00e+001.90418174
GO:0004842ubiquitin-protein transferase activity2.42e-011.00e+001.863117179
GO:0003713transcription coactivator activity2.48e-011.00e+001.823121184
GO:0005856cytoskeleton2.55e-011.00e+001.77718190
GO:0045944positive regulation of transcription from RNA polymerase II promoter2.60e-011.00e+001.016229644
GO:0005743mitochondrial inner membrane2.64e-011.00e+001.72419197
GO:0005525GTP binding2.64e-011.00e+001.724112197
GO:0005739mitochondrion2.69e-011.00e+000.982232659
GO:0015031protein transport2.70e-011.00e+001.681110203
GO:0006357regulation of transcription from RNA polymerase II promoter2.70e-011.00e+001.681114203
GO:0007268synaptic transmission2.83e-011.00e+001.60517214
GO:0030054cell junction2.87e-011.00e+001.57815218
GO:0005886plasma membrane2.88e-011.00e+000.5464461784
GO:0006200ATP catabolic process2.89e-011.00e+001.572113219
GO:0030198extracellular matrix organization2.91e-011.00e+001.55917221
GO:0007186G-protein coupled receptor signaling pathway3.00e-011.00e+001.50714229
GO:0006355regulation of transcription, DNA-templated3.02e-011.00e+000.865231715
GO:0008283cell proliferation3.11e-011.00e+001.44618239
GO:0005925focal adhesion3.56e-011.00e+001.207114282
GO:0009986cell surface3.65e-011.00e+001.16215291
GO:0007596blood coagulation4.12e-011.00e+000.941113339
GO:0006366transcription from RNA polymerase II promoter4.13e-011.00e+000.933123341
GO:0005509calcium ion binding4.23e-011.00e+000.89119351
GO:0070062extracellular vesicular exosome4.74e-011.00e+000.2513511641
GO:0006351transcription, DNA-templated5.04e-011.00e+000.2752471076
GO:0045087innate immune response5.09e-011.00e+000.526112452
GO:0005730nucleolus5.74e-011.00e+000.0972741217
GO:0005887integral component of plasma membrane5.98e-011.00e+000.17918575
GO:0007165signal transduction6.25e-011.00e+000.075124618
GO:0008270zinc ion binding6.87e-011.00e+00-0.159139727
GO:0016021integral component of membrane9.22e-011.00e+00-1.2291191526