reg-snw-64146

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.308	7.82e-08	2.33e-02	1.85e-02

chia-screen-data-Fav-reg-snw-64146 subnetwork

Genes (12)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
SYNCRIP	10492	42	-2.401	2.503	144	TF	Yes	Yes
PHB2	11331	17	-2.236	2.449	11	-	Yes	-
DPH2	1802	1	-1.710	2.308	3	-	-	-
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
ETF1	2107	35	-2.829	2.503	6	-	Yes	Yes
GSPT1	2935	32	-2.313	2.503	17	-	Yes	Yes
CCT7	10574	40	-2.335	2.459	38	-	Yes	-
CPSF3	51692	43	-2.686	2.503	31	-	Yes	Yes
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
MRPL18	29074	2	-1.788	2.308	15	-	-	-
IPO4	79711	4	-1.739	2.449	58	TF	-	-
[ PDF ]	64146	1	-1.296	2.308	3	-	-	-

Interactions (11)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
GSPT1	2935	IPO4	79711	pd	<	reg.ITFP.txt: no annot
CCT7	10574	IPO4	79711	pd	<	reg.ITFP.txt: no annot
DPH2	1802	IPO4	79711	pd	<	reg.ITFP.txt: no annot
PDF	64146	IPO4	79711	pd	<	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
PHB2	11331	IPO4	79711	pd	<	reg.ITFP.txt: no annot
ETF1	2107	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
MRPL18	29074	IPO4	79711	pd	<	reg.ITFP.txt: no annot
GSPT1	2935	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
SYNCRIP	10492	CPSF3	51692	pd	>	reg.ITFP.txt: no annot
GPS1	2873	PHB2	11331	pd	>	reg.ITFP.txt: no annot

Related GO terms (119)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0003747	translation release factor activity	1.38e-06	1.35e-02	9.668	2	2	2
GO:0006479	protein methylation	7.57e-05	7.39e-01	7.209	2	2	11
GO:0005739	mitochondrion	7.33e-04	1.00e+00	2.626	5	32	659
GO:0006412	translation	1.16e-03	1.00e+00	3.778	3	12	178
GO:0042586	peptide deformylase activity	1.23e-03	1.00e+00	9.668	1	1	1
GO:0016149	translation release factor activity, codon specific	1.23e-03	1.00e+00	9.668	1	1	1
GO:0008079	translation termination factor activity	1.23e-03	1.00e+00	9.668	1	1	1
GO:0035928	rRNA import into mitochondrion	2.46e-03	1.00e+00	8.668	1	1	2
GO:0008097	5S rRNA binding	2.46e-03	1.00e+00	8.668	1	1	2
GO:0031365	N-terminal protein amino acid modification	2.46e-03	1.00e+00	8.668	1	1	2
GO:0006415	translational termination	2.59e-03	1.00e+00	4.691	2	2	63
GO:0003723	RNA binding	2.97e-03	1.00e+00	3.305	3	22	247
GO:0001649	osteoblast differentiation	3.56e-03	1.00e+00	4.459	2	5	74
GO:0030529	ribonucleoprotein complex	4.35e-03	1.00e+00	4.311	2	5	82
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	4.56e-03	1.00e+00	4.276	2	5	84
GO:0006449	regulation of translational termination	4.91e-03	1.00e+00	7.668	1	1	4
GO:0018206	peptidyl-methionine modification	4.91e-03	1.00e+00	7.668	1	1	4
GO:0097452	GAIT complex	4.91e-03	1.00e+00	7.668	1	2	4
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	4.91e-03	1.00e+00	7.668	1	1	4
GO:0004521	endoribonuclease activity	6.13e-03	1.00e+00	7.347	1	1	5
GO:0060744	mammary gland branching involved in thelarche	6.13e-03	1.00e+00	7.347	1	1	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	6.13e-03	1.00e+00	7.347	1	1	5
GO:0006398	histone mRNA 3'-end processing	6.13e-03	1.00e+00	7.347	1	1	5
GO:0071204	histone pre-mRNA 3'end processing complex	6.13e-03	1.00e+00	7.347	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	6.13e-03	1.00e+00	7.347	1	2	5
GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	6.13e-03	1.00e+00	7.347	1	1	5
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	6.13e-03	1.00e+00	7.347	1	1	5
GO:0050847	progesterone receptor signaling pathway	7.35e-03	1.00e+00	7.083	1	2	6
GO:0070937	CRD-mediated mRNA stability complex	7.35e-03	1.00e+00	7.083	1	2	6
GO:0002199	zona pellucida receptor complex	8.57e-03	1.00e+00	6.861	1	4	7
GO:0005832	chaperonin-containing T-complex	8.57e-03	1.00e+00	6.861	1	4	7
GO:0008409	5'-3' exonuclease activity	8.57e-03	1.00e+00	6.861	1	2	7
GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	8.57e-03	1.00e+00	6.861	1	2	7
GO:0010944	negative regulation of transcription by competitive promoter binding	9.79e-03	1.00e+00	6.668	1	1	8
GO:0010388	cullin deneddylation	9.79e-03	1.00e+00	6.668	1	4	8
GO:0000398	mRNA splicing, via spliceosome	1.03e-02	1.00e+00	3.668	2	15	128
GO:0006379	mRNA cleavage	1.10e-02	1.00e+00	6.499	1	2	9
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	1.10e-02	1.00e+00	6.499	1	3	9
GO:0071354	cellular response to interleukin-6	1.10e-02	1.00e+00	6.499	1	1	9
GO:0005095	GTPase inhibitor activity	1.22e-02	1.00e+00	6.347	1	1	10
GO:0008143	poly(A) binding	1.22e-02	1.00e+00	6.347	1	2	10
GO:0060766	negative regulation of androgen receptor signaling pathway	1.34e-02	1.00e+00	6.209	1	4	11
GO:0060749	mammary gland alveolus development	1.59e-02	1.00e+00	5.968	1	1	13
GO:0006335	DNA replication-dependent nucleosome assembly	1.59e-02	1.00e+00	5.968	1	2	13
GO:0006336	DNA replication-independent nucleosome assembly	1.59e-02	1.00e+00	5.968	1	2	13
GO:0008380	RNA splicing	1.68e-02	1.00e+00	3.302	2	21	165
GO:0016575	histone deacetylation	1.71e-02	1.00e+00	5.861	1	2	14
GO:0000188	inactivation of MAPK activity	1.83e-02	1.00e+00	5.762	1	1	15
GO:0007339	binding of sperm to zona pellucida	1.83e-02	1.00e+00	5.762	1	4	15
GO:0043022	ribosome binding	2.07e-02	1.00e+00	5.581	1	2	17
GO:0006378	mRNA polyadenylation	2.19e-02	1.00e+00	5.499	1	3	18
GO:0005743	mitochondrial inner membrane	2.34e-02	1.00e+00	3.046	2	9	197
GO:0071346	cellular response to interferon-gamma	2.43e-02	1.00e+00	5.347	1	2	20
GO:0071897	DNA biosynthetic process	2.43e-02	1.00e+00	5.347	1	2	20
GO:0005761	mitochondrial ribosome	2.43e-02	1.00e+00	5.347	1	1	20
GO:0008536	Ran GTPase binding	2.55e-02	1.00e+00	5.276	1	1	21
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	2.55e-02	1.00e+00	5.276	1	2	21
GO:0043234	protein complex	2.64e-02	1.00e+00	2.954	2	13	210
GO:0030331	estrogen receptor binding	2.67e-02	1.00e+00	5.209	1	2	22
GO:0051084	'de novo' posttranslational protein folding	2.67e-02	1.00e+00	5.209	1	4	22
GO:0008180	COP9 signalosome	2.91e-02	1.00e+00	5.083	1	6	24
GO:0017148	negative regulation of translation	3.98e-02	1.00e+00	4.624	1	5	33
GO:0007254	JNK cascade	4.10e-02	1.00e+00	4.581	1	1	34
GO:0031124	mRNA 3'-end processing	4.22e-02	1.00e+00	4.539	1	4	35
GO:0044297	cell body	4.22e-02	1.00e+00	4.539	1	5	35
GO:0006369	termination of RNA polymerase II transcription	4.57e-02	1.00e+00	4.421	1	5	38
GO:0006396	RNA processing	4.81e-02	1.00e+00	4.347	1	4	40
GO:0006406	mRNA export from nucleus	5.28e-02	1.00e+00	4.209	1	7	44
GO:0045892	negative regulation of transcription, DNA-templated	5.59e-02	1.00e+00	2.360	2	17	317
GO:0005643	nuclear pore	6.09e-02	1.00e+00	3.996	1	12	51
GO:0044267	cellular protein metabolic process	6.74e-02	1.00e+00	2.209	2	14	352
GO:0044822	poly(A) RNA binding	6.88e-02	1.00e+00	1.611	3	45	799
GO:0042826	histone deacetylase binding	6.90e-02	1.00e+00	3.810	1	5	58
GO:0071013	catalytic step 2 spliceosome	7.25e-02	1.00e+00	3.738	1	5	61
GO:0005737	cytoplasm	7.55e-02	1.00e+00	0.891	6	127	2633
GO:0005515	protein binding	7.83e-02	1.00e+00	0.659	8	198	4124
GO:0030308	negative regulation of cell growth	8.28e-02	1.00e+00	3.539	1	3	70
GO:0051082	unfolded protein binding	8.28e-02	1.00e+00	3.539	1	5	70
GO:0005654	nucleoplasm	8.58e-02	1.00e+00	1.479	3	68	876
GO:0016363	nuclear matrix	8.62e-02	1.00e+00	3.479	1	10	73
GO:0006886	intracellular protein transport	1.04e-01	1.00e+00	3.193	1	2	89
GO:0005506	iron ion binding	1.07e-01	1.00e+00	3.145	1	4	92
GO:0006457	protein folding	1.13e-01	1.00e+00	3.069	1	5	97
GO:0003735	structural constituent of ribosome	1.26e-01	1.00e+00	2.900	1	2	109
GO:0000790	nuclear chromatin	1.26e-01	1.00e+00	2.900	1	9	109
GO:0042981	regulation of apoptotic process	1.29e-01	1.00e+00	2.861	1	4	112
GO:0007049	cell cycle	1.33e-01	1.00e+00	2.823	1	8	115
GO:0003924	GTPase activity	1.37e-01	1.00e+00	2.774	1	7	119
GO:0010467	gene expression	1.38e-01	1.00e+00	1.605	2	49	535
GO:0000082	G1/S transition of mitotic cell cycle	1.43e-01	1.00e+00	2.703	1	4	125
GO:0006184	GTP catabolic process	1.49e-01	1.00e+00	2.646	1	7	130
GO:0044212	transcription regulatory region DNA binding	1.62e-01	1.00e+00	2.509	1	13	143
GO:0005622	intracellular	1.64e-01	1.00e+00	2.489	1	2	145
GO:0016020	membrane	1.78e-01	1.00e+00	1.016	3	56	1207
GO:0005874	microtubule	1.83e-01	1.00e+00	2.320	1	10	163
GO:0016071	mRNA metabolic process	1.90e-01	1.00e+00	2.259	1	10	170
GO:0000166	nucleotide binding	1.96e-01	1.00e+00	2.209	1	13	176
GO:0016070	RNA metabolic process	2.08e-01	1.00e+00	2.114	1	10	188
GO:0005525	GTP binding	2.17e-01	1.00e+00	2.046	1	12	197
GO:0015031	protein transport	2.23e-01	1.00e+00	2.003	1	10	203
GO:0019899	enzyme binding	2.30e-01	1.00e+00	1.954	1	7	210
GO:0008285	negative regulation of cell proliferation	2.92e-01	1.00e+00	1.555	1	11	277
GO:0008284	positive regulation of cell proliferation	2.94e-01	1.00e+00	1.544	1	8	279
GO:0070062	extracellular vesicular exosome	3.27e-01	1.00e+00	0.573	3	51	1641
GO:0006366	transcription from RNA polymerase II promoter	3.47e-01	1.00e+00	1.255	1	23	341
GO:0042802	identical protein binding	3.58e-01	1.00e+00	1.201	1	15	354
GO:0045893	positive regulation of transcription, DNA-templated	3.77e-01	1.00e+00	1.110	1	21	377
GO:0005783	endoplasmic reticulum	3.80e-01	1.00e+00	1.095	1	12	381
GO:0016032	viral process	4.16e-01	1.00e+00	0.927	1	30	428
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	4.37e-01	1.00e+00	0.836	1	29	456
GO:0005887	integral component of plasma membrane	5.17e-01	1.00e+00	0.501	1	8	575
GO:0007165	signal transduction	5.44e-01	1.00e+00	0.397	1	24	618
GO:0005615	extracellular space	5.63e-01	1.00e+00	0.322	1	15	651
GO:0006355	regulation of transcription, DNA-templated	5.99e-01	1.00e+00	0.187	1	31	715
GO:0005634	nucleus	6.04e-01	1.00e+00	0.004	4	158	3246
GO:0005829	cytosol	6.74e-01	1.00e+00	-0.135	2	88	1787
GO:0005524	ATP binding	6.83e-01	1.00e+00	-0.132	1	37	892
GO:0046872	metal ion binding	7.01e-01	1.00e+00	-0.199	1	24	934
GO:0006351	transcription, DNA-templated	7.54e-01	1.00e+00	-0.403	1	47	1076

chia-Fav

reg-snw-64146

Statistics

Genes (12)

Interactions (11)

Related GO terms (119)