reg-snw-6051

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.223	2.19e-07	4.06e-02	3.10e-02

chia-screen-data-Fav-reg-snw-6051 subnetwork

Genes (15)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
RNF40	9810	10	-2.082	2.492	38	TF	Yes	-
OTUB1	55611	4	-1.774	2.268	45	-	-	-
RHOA	387	17	-2.408	2.644	10	-	Yes	Yes
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
FTSJ1	24140	43	-2.463	2.689	35	-	Yes	Yes
POLR2E	5434	30	-2.037	2.644	201	TF	Yes	-
XPNPEP1	7511	8	-1.779	2.386	76	TF	-	-
VARS	7407	60	-2.366	2.689	124	TF	Yes	-
GTF2A2	2958	9	-1.938	2.377	41	TF	-	-
HNRNPU	3192	39	-2.869	2.644	33	-	Yes	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
[ RNPEP ]	6051	1	-1.291	2.223	13	TF	-	-
DRG2	1819	15	-2.526	2.492	11	-	Yes	-
SYMPK	8189	11	-1.890	2.492	51	TF	-	-
AP2S1	1175	5	-1.558	2.367	39	-	-	-

Interactions (20)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
HNRNPU	3192	POLR2E	5434	pd	<	reg.ITFP.txt: no annot
DRG2	1819	SYMPK	8189	pd	<	reg.ITFP.txt: no annot
AP2S1	1175	POLR2E	5434	pd	<	reg.ITFP.txt: no annot
RNPEP	6051	OTUB1	55611	pd	>	reg.ITFP.txt: no annot
RHOA	387	POLR2E	5434	pd	<	reg.ITFP.txt: no annot
VARS	7407	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
PHB	5245	VARS	7407	pd	<	reg.ITFP.txt: no annot
POLR2E	5434	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
POLR2E	5434	VARS	7407	pd	<>	reg.ITFP.txt: no annot
AP2S1	1175	GTF2A2	2958	pd	<	reg.ITFP.txt: no annot
AP2S1	1175	XPNPEP1	7511	pd	<	reg.ITFP.txt: no annot
POLR2E	5434	OTUB1	55611	pd	>	reg.ITFP.txt: no annot
AP2S1	1175	VARS	7407	pd	<	reg.ITFP.txt: no annot
SYMPK	8189	OTUB1	55611	pd	>	reg.ITFP.txt: no annot
AP2S1	1175	RNPEP	6051	pd	<	reg.ITFP.txt: no annot
POLR2E	5434	XPNPEP1	7511	pd	<>	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
RNF40	9810	OTUB1	55611	pd	>	reg.ITFP.txt: no annot
XPNPEP1	7511	SYMPK	8189	pd	<>	reg.ITFP.txt: no annot
SYMPK	8189	RNF40	9810	pd	<>	reg.ITFP.txt: no annot

Related GO terms (181)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0004177	aminopeptidase activity	1.98e-04	1.00e+00	6.539	2	3	14
GO:0004832	valine-tRNA ligase activity	1.54e-03	1.00e+00	9.347	1	1	1
GO:0061383	trabecula morphogenesis	1.54e-03	1.00e+00	9.347	1	1	1
GO:0002128	tRNA nucleoside ribose methylation	1.54e-03	1.00e+00	9.347	1	1	1
GO:0008175	tRNA methyltransferase activity	1.54e-03	1.00e+00	9.347	1	1	1
GO:0006438	valyl-tRNA aminoacylation	1.54e-03	1.00e+00	9.347	1	1	1
GO:0006368	transcription elongation from RNA polymerase II promoter	2.79e-03	1.00e+00	4.646	2	8	52
GO:0033688	regulation of osteoblast proliferation	3.07e-03	1.00e+00	8.347	1	1	2
GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly	3.07e-03	1.00e+00	8.347	1	1	2
GO:0019784	NEDD8-specific protease activity	3.07e-03	1.00e+00	8.347	1	1	2
GO:0016032	viral process	3.38e-03	1.00e+00	2.605	4	30	428
GO:1901315	negative regulation of histone H2A K63-linked ubiquitination	4.60e-03	1.00e+00	7.762	1	2	3
GO:0004301	epoxide hydrolase activity	4.60e-03	1.00e+00	7.762	1	1	3
GO:0070006	metalloaminopeptidase activity	4.60e-03	1.00e+00	7.762	1	1	3
GO:0001649	osteoblast differentiation	5.58e-03	1.00e+00	4.137	2	5	74
GO:0036089	cleavage furrow formation	6.13e-03	1.00e+00	7.347	1	1	4
GO:0033503	HULC complex	6.13e-03	1.00e+00	7.347	1	1	4
GO:0010815	bradykinin catabolic process	6.13e-03	1.00e+00	7.347	1	1	4
GO:0006508	proteolysis	6.99e-03	1.00e+00	2.887	3	11	264
GO:0010467	gene expression	7.49e-03	1.00e+00	2.283	4	49	535
GO:0008235	metalloexopeptidase activity	7.66e-03	1.00e+00	7.025	1	2	5
GO:2000780	negative regulation of double-strand break repair	7.66e-03	1.00e+00	7.025	1	2	5
GO:0038027	apolipoprotein A-I-mediated signaling pathway	7.66e-03	1.00e+00	7.025	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	7.66e-03	1.00e+00	7.025	1	2	5
GO:0043931	ossification involved in bone maturation	7.66e-03	1.00e+00	7.025	1	1	5
GO:0005672	transcription factor TFIIA complex	7.66e-03	1.00e+00	7.025	1	1	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	7.66e-03	1.00e+00	7.025	1	1	5
GO:0002161	aminoacyl-tRNA editing activity	7.66e-03	1.00e+00	7.025	1	1	5
GO:0005654	nucleoplasm	8.04e-03	1.00e+00	1.894	5	68	876
GO:0050847	progesterone receptor signaling pathway	9.18e-03	1.00e+00	6.762	1	2	6
GO:0002181	cytoplasmic translation	9.18e-03	1.00e+00	6.762	1	1	6
GO:0001055	RNA polymerase II activity	9.18e-03	1.00e+00	6.762	1	3	6
GO:0043297	apical junction assembly	9.18e-03	1.00e+00	6.762	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	9.18e-03	1.00e+00	6.762	1	2	6
GO:0035615	clathrin adaptor activity	1.07e-02	1.00e+00	6.539	1	1	7
GO:0033523	histone H2B ubiquitination	1.07e-02	1.00e+00	6.539	1	1	7
GO:0090307	spindle assembly involved in mitosis	1.22e-02	1.00e+00	6.347	1	2	8
GO:0006450	regulation of translational fidelity	1.22e-02	1.00e+00	6.347	1	1	8
GO:0010944	negative regulation of transcription by competitive promoter binding	1.22e-02	1.00e+00	6.347	1	1	8
GO:0010388	cullin deneddylation	1.22e-02	1.00e+00	6.347	1	4	8
GO:0008242	omega peptidase activity	1.22e-02	1.00e+00	6.347	1	1	8
GO:0010390	histone monoubiquitination	1.22e-02	1.00e+00	6.347	1	2	8
GO:0043296	apical junction complex	1.22e-02	1.00e+00	6.347	1	1	8
GO:0030122	AP-2 adaptor complex	1.37e-02	1.00e+00	6.177	1	2	9
GO:0071354	cellular response to interleukin-6	1.37e-02	1.00e+00	6.177	1	1	9
GO:0030100	regulation of endocytosis	1.37e-02	1.00e+00	6.177	1	1	9
GO:0048268	clathrin coat assembly	1.37e-02	1.00e+00	6.177	1	2	9
GO:0072583	clathrin-mediated endocytosis	1.37e-02	1.00e+00	6.177	1	1	9
GO:0005736	DNA-directed RNA polymerase I complex	1.53e-02	1.00e+00	6.025	1	4	10
GO:0005095	GTPase inhibitor activity	1.53e-02	1.00e+00	6.025	1	1	10
GO:0050919	negative chemotaxis	1.53e-02	1.00e+00	6.025	1	1	10
GO:0019370	leukotriene biosynthetic process	1.53e-02	1.00e+00	6.025	1	1	10
GO:0001054	RNA polymerase I activity	1.53e-02	1.00e+00	6.025	1	4	10
GO:0035307	positive regulation of protein dephosphorylation	1.53e-02	1.00e+00	6.025	1	1	10
GO:0000398	mRNA splicing, via spliceosome	1.60e-02	1.00e+00	3.347	2	15	128
GO:0060766	negative regulation of androgen receptor signaling pathway	1.68e-02	1.00e+00	5.887	1	4	11
GO:0017025	TBP-class protein binding	1.83e-02	1.00e+00	5.762	1	1	12
GO:0031625	ubiquitin protein ligase binding	1.85e-02	1.00e+00	3.238	2	7	138
GO:0017075	syntaxin-1 binding	1.98e-02	1.00e+00	5.646	1	1	13
GO:0050772	positive regulation of axonogenesis	1.98e-02	1.00e+00	5.646	1	2	13
GO:0050770	regulation of axonogenesis	1.98e-02	1.00e+00	5.646	1	3	13
GO:0005666	DNA-directed RNA polymerase III complex	1.98e-02	1.00e+00	5.646	1	3	13
GO:0005665	DNA-directed RNA polymerase II, core complex	1.98e-02	1.00e+00	5.646	1	3	13
GO:0001056	RNA polymerase III activity	1.98e-02	1.00e+00	5.646	1	3	13
GO:0071108	protein K48-linked deubiquitination	1.98e-02	1.00e+00	5.646	1	1	13
GO:0042346	positive regulation of NF-kappaB import into nucleus	1.98e-02	1.00e+00	5.646	1	1	13
GO:0006386	termination of RNA polymerase III transcription	2.13e-02	1.00e+00	5.539	1	3	14
GO:0006385	transcription elongation from RNA polymerase III promoter	2.13e-02	1.00e+00	5.539	1	3	14
GO:0050771	negative regulation of axonogenesis	2.13e-02	1.00e+00	5.539	1	2	14
GO:0016575	histone deacetylation	2.13e-02	1.00e+00	5.539	1	2	14
GO:0000188	inactivation of MAPK activity	2.28e-02	1.00e+00	5.440	1	1	15
GO:0032467	positive regulation of cytokinesis	2.43e-02	1.00e+00	5.347	1	1	16
GO:0017022	myosin binding	2.43e-02	1.00e+00	5.347	1	2	16
GO:0006367	transcription initiation from RNA polymerase II promoter	2.46e-02	1.00e+00	3.016	2	18	161
GO:0042803	protein homodimerization activity	2.57e-02	1.00e+00	2.190	3	13	428
GO:0008380	RNA splicing	2.58e-02	1.00e+00	2.980	2	21	165
GO:0003899	DNA-directed RNA polymerase activity	2.73e-02	1.00e+00	5.177	1	3	18
GO:0006378	mRNA polyadenylation	2.73e-02	1.00e+00	5.177	1	3	18
GO:0036464	cytoplasmic ribonucleoprotein granule	2.88e-02	1.00e+00	5.099	1	1	19
GO:0071897	DNA biosynthetic process	3.03e-02	1.00e+00	5.025	1	2	20
GO:0050690	regulation of defense response to virus by virus	3.33e-02	1.00e+00	4.887	1	1	22
GO:0005856	cytoskeleton	3.35e-02	1.00e+00	2.777	2	8	190
GO:0001103	RNA polymerase II repressing transcription factor binding	3.48e-02	1.00e+00	4.823	1	2	23
GO:0002376	immune system process	3.48e-02	1.00e+00	4.823	1	2	23
GO:0030669	clathrin-coated endocytic vesicle membrane	3.48e-02	1.00e+00	4.823	1	1	23
GO:0005525	GTP binding	3.58e-02	1.00e+00	2.724	2	12	197
GO:0006370	7-methylguanosine mRNA capping	3.63e-02	1.00e+00	4.762	1	5	24
GO:0008180	COP9 signalosome	3.63e-02	1.00e+00	4.762	1	6	24
GO:0048011	neurotrophin TRK receptor signaling pathway	3.65e-02	1.00e+00	2.710	2	8	199
GO:0006281	DNA repair	3.78e-02	1.00e+00	2.681	2	24	203
GO:0030145	manganese ion binding	3.92e-02	1.00e+00	4.646	1	3	26
GO:0051496	positive regulation of stress fiber assembly	3.92e-02	1.00e+00	4.646	1	2	26
GO:0006360	transcription from RNA polymerase I promoter	4.07e-02	1.00e+00	4.592	1	4	27
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	4.22e-02	1.00e+00	4.539	1	2	28
GO:0030054	cell junction	4.30e-02	1.00e+00	2.578	2	5	218
GO:0006418	tRNA aminoacylation for protein translation	4.37e-02	1.00e+00	4.489	1	4	29
GO:0006383	transcription from RNA polymerase III promoter	4.37e-02	1.00e+00	4.489	1	6	29
GO:0043130	ubiquitin binding	4.51e-02	1.00e+00	4.440	1	3	30
GO:0032154	cleavage furrow	4.51e-02	1.00e+00	4.440	1	3	30
GO:0007411	axon guidance	5.00e-02	1.00e+00	2.458	2	8	237
GO:0021762	substantia nigra development	5.10e-02	1.00e+00	4.259	1	1	34
GO:0007254	JNK cascade	5.10e-02	1.00e+00	4.259	1	1	34
GO:0008565	protein transporter activity	5.25e-02	1.00e+00	4.217	1	2	35
GO:0050434	positive regulation of viral transcription	5.25e-02	1.00e+00	4.217	1	5	35
GO:0007266	Rho protein signal transduction	5.25e-02	1.00e+00	4.217	1	2	35
GO:0030334	regulation of cell migration	5.39e-02	1.00e+00	4.177	1	2	36
GO:0030666	endocytic vesicle membrane	5.39e-02	1.00e+00	4.177	1	1	36
GO:0006396	RNA processing	5.98e-02	1.00e+00	4.025	1	4	40
GO:0006283	transcription-coupled nucleotide-excision repair	5.98e-02	1.00e+00	4.025	1	6	40
GO:0004843	ubiquitin-specific protease activity	6.84e-02	1.00e+00	3.823	1	2	46
GO:0032481	positive regulation of type I interferon production	7.13e-02	1.00e+00	3.762	1	3	48
GO:0000151	ubiquitin ligase complex	7.13e-02	1.00e+00	3.762	1	4	48
GO:0005739	mitochondrion	7.58e-02	1.00e+00	1.567	3	32	659
GO:0006289	nucleotide-excision repair	7.84e-02	1.00e+00	3.619	1	6	53
GO:0045666	positive regulation of neuron differentiation	7.84e-02	1.00e+00	3.619	1	3	53
GO:0005737	cytoplasm	8.10e-02	1.00e+00	0.791	7	127	2633
GO:0042826	histone deacetylase binding	8.55e-02	1.00e+00	3.489	1	5	58
GO:0071013	catalytic step 2 spliceosome	8.98e-02	1.00e+00	3.416	1	5	61
GO:0070062	extracellular vesicular exosome	9.22e-02	1.00e+00	0.988	5	51	1641
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	9.40e-02	1.00e+00	3.347	1	3	64
GO:0005923	tight junction	9.40e-02	1.00e+00	3.347	1	2	64
GO:0006366	transcription from RNA polymerase II promoter	9.47e-02	1.00e+00	1.933	2	23	341
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	9.82e-02	1.00e+00	3.280	1	5	67
GO:0030308	negative regulation of cell growth	1.02e-01	1.00e+00	3.217	1	3	70
GO:0016020	membrane	1.04e-01	1.00e+00	1.109	4	56	1207
GO:0030496	midbody	1.07e-01	1.00e+00	3.157	1	6	73
GO:0051056	regulation of small GTPase mediated signal transduction	1.11e-01	1.00e+00	3.099	1	2	76
GO:0005938	cell cortex	1.12e-01	1.00e+00	3.080	1	6	77
GO:0030529	ribonucleoprotein complex	1.19e-01	1.00e+00	2.989	1	5	82
GO:0005215	transporter activity	1.19e-01	1.00e+00	2.989	1	5	82
GO:0048015	phosphatidylinositol-mediated signaling	1.20e-01	1.00e+00	2.971	1	2	83
GO:0005829	cytosol	1.23e-01	1.00e+00	0.865	5	88	1787
GO:0030027	lamellipodium	1.27e-01	1.00e+00	2.887	1	3	88
GO:0006886	intracellular protein transport	1.28e-01	1.00e+00	2.871	1	2	89
GO:0005515	protein binding	1.29e-01	1.00e+00	0.507	9	198	4124
GO:0030036	actin cytoskeleton organization	1.30e-01	1.00e+00	2.855	1	4	90
GO:0006511	ubiquitin-dependent protein catabolic process	1.32e-01	1.00e+00	2.823	1	6	92
GO:0007179	transforming growth factor beta receptor signaling pathway	1.52e-01	1.00e+00	2.605	1	5	107
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	1.54e-01	1.00e+00	2.592	1	2	108
GO:0042981	regulation of apoptotic process	1.59e-01	1.00e+00	2.539	1	4	112
GO:0043005	neuron projection	1.60e-01	1.00e+00	2.526	1	6	113
GO:0007049	cell cycle	1.63e-01	1.00e+00	2.501	1	8	115
GO:0003924	GTPase activity	1.68e-01	1.00e+00	2.452	1	7	119
GO:0006974	cellular response to DNA damage stimulus	1.71e-01	1.00e+00	2.428	1	11	121
GO:0006184	GTP catabolic process	1.82e-01	1.00e+00	2.324	1	7	130
GO:0032403	protein complex binding	1.82e-01	1.00e+00	2.324	1	5	130
GO:0030168	platelet activation	1.96e-01	1.00e+00	2.207	1	5	141
GO:0007173	epidermal growth factor receptor signaling pathway	1.97e-01	1.00e+00	2.197	1	5	142
GO:0044212	transcription regulatory region DNA binding	1.99e-01	1.00e+00	2.187	1	13	143
GO:0005634	nucleus	2.01e-01	1.00e+00	0.489	7	158	3246
GO:0016874	ligase activity	2.02e-01	1.00e+00	2.157	1	11	146
GO:0007264	small GTPase mediated signal transduction	2.37e-01	1.00e+00	1.904	1	8	174
GO:0004842	ubiquitin-protein transferase activity	2.42e-01	1.00e+00	1.863	1	17	179
GO:0007165	signal transduction	2.45e-01	1.00e+00	1.075	2	24	618
GO:0003713	transcription coactivator activity	2.48e-01	1.00e+00	1.823	1	21	184
GO:0005743	mitochondrial inner membrane	2.64e-01	1.00e+00	1.724	1	9	197
GO:0008134	transcription factor binding	2.77e-01	1.00e+00	1.639	1	10	209
GO:0019899	enzyme binding	2.78e-01	1.00e+00	1.632	1	7	210
GO:0007268	synaptic transmission	2.83e-01	1.00e+00	1.605	1	7	214
GO:0005886	plasma membrane	2.88e-01	1.00e+00	0.546	4	46	1784
GO:0008270	zinc ion binding	3.09e-01	1.00e+00	0.841	2	39	727
GO:0007155	cell adhesion	3.16e-01	1.00e+00	1.416	1	8	244
GO:0003723	RNA binding	3.19e-01	1.00e+00	1.398	1	22	247
GO:0046982	protein heterodimerization activity	3.38e-01	1.00e+00	1.297	1	11	265
GO:0008285	negative regulation of cell proliferation	3.51e-01	1.00e+00	1.233	1	11	277
GO:0005925	focal adhesion	3.56e-01	1.00e+00	1.207	1	14	282
GO:0009986	cell surface	3.65e-01	1.00e+00	1.162	1	5	291
GO:0045892	negative regulation of transcription, DNA-templated	3.91e-01	1.00e+00	1.038	1	17	317
GO:0005524	ATP binding	4.04e-01	1.00e+00	0.546	2	37	892
GO:0007596	blood coagulation	4.12e-01	1.00e+00	0.941	1	13	339
GO:0003677	DNA binding	4.35e-01	1.00e+00	0.459	2	52	947
GO:0045893	positive regulation of transcription, DNA-templated	4.46e-01	1.00e+00	0.788	1	21	377
GO:0045087	innate immune response	5.09e-01	1.00e+00	0.526	1	12	452
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	5.12e-01	1.00e+00	0.514	1	29	456
GO:0005730	nucleolus	5.74e-01	1.00e+00	0.097	2	74	1217
GO:0005887	integral component of plasma membrane	5.98e-01	1.00e+00	0.179	1	8	575
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	6.41e-01	1.00e+00	0.016	1	29	644
GO:0005615	extracellular space	6.45e-01	1.00e+00	0.000	1	15	651
GO:0005576	extracellular region	6.52e-01	1.00e+00	-0.026	1	15	663
GO:0006355	regulation of transcription, DNA-templated	6.81e-01	1.00e+00	-0.135	1	31	715
GO:0044822	poly(A) RNA binding	7.22e-01	1.00e+00	-0.296	1	45	799

chia-Fav

reg-snw-6051

Statistics

Genes (15)

Interactions (20)

Related GO terms (181)