reg-snw-2783

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.192 3.17e-07 4.92e-02 3.73e-02
chia-screen-data-Fav-reg-snw-2783 subnetwork

Genes (16)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
EML3 256364 1-1.6212.1921TF--
PXN 5829 1-2.5542.1926TFYesYes
RHOA 387 17-2.4082.64410-YesYes
PHB 5245 82-2.7432.68936-YesYes
VARS 7407 60-2.3662.689124TFYes-
GTF2A2 2958 9-1.9382.37741TF--
SF3A2 8175 3-1.8452.47217TF--
[ GNB2 ] 2783 1-1.1282.1928TF--
POLR2E 5434 30-2.0372.644201TFYes-
ARHGDIA 396 1-1.3492.19227---
FTSJ1 24140 43-2.4632.68935-YesYes
XPNPEP1 7511 8-1.7792.38676TF--
HNRNPU 3192 39-2.8692.64433-Yes-
GPS1 2873 86-3.6212.68936TFYesYes
AP2S1 1175 5-1.5582.36739---
SF3A1 10291 3-2.7872.4728-YesYes

Interactions (18)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
SF3A2 8175 SF3A1 10291 pd > reg.ITFP.txt: no annot
HNRNPU 3192 POLR2E 5434 pd < reg.ITFP.txt: no annot
AP2S1 1175 POLR2E 5434 pd < reg.ITFP.txt: no annot
ARHGDIA 396 GNB2 2783 pd < reg.ITFP.txt: no annot
RHOA 387 POLR2E 5434 pd < reg.ITFP.txt: no annot
AP2S1 1175 GNB2 2783 pd < reg.ITFP.txt: no annot
ARHGDIA 396 SF3A2 8175 pd < reg.ITFP.txt: no annot
VARS 7407 FTSJ1 24140 pd > reg.ITFP.txt: no annot
PHB 5245 VARS 7407 pd < reg.ITFP.txt: no annot
ARHGDIA 396 EML3 256364 pd < reg.ITFP.txt: no annot
POLR2E 5434 FTSJ1 24140 pd > reg.ITFP.txt: no annot
POLR2E 5434 VARS 7407 pd <> reg.ITFP.txt: no annot
AP2S1 1175 GTF2A2 2958 pd < reg.ITFP.txt: no annot
AP2S1 1175 XPNPEP1 7511 pd < reg.ITFP.txt: no annot
AP2S1 1175 VARS 7407 pd < reg.ITFP.txt: no annot
POLR2E 5434 XPNPEP1 7511 pd <> reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot
ARHGDIA 396 PXN 5829 pd < reg.ITFP.txt: no annot

Related GO terms (204)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0000389mRNA 3'-splice site recognition1.51e-051.47e-018.253224
GO:0000398mRNA splicing, via spliceosome4.54e-054.43e-014.253415128
GO:0008380RNA splicing1.22e-041.00e+003.887421165
GO:0071013catalytic step 2 spliceosome1.23e-041.00e+004.9083561
GO:0010467gene expression1.31e-041.00e+002.775649535
GO:0050772positive regulation of axonogenesis1.94e-041.00e+006.5532213
GO:0050770regulation of axonogenesis1.94e-041.00e+006.5532313
GO:0050771negative regulation of axonogenesis2.26e-041.00e+006.4462214
GO:0007266Rho protein signal transduction1.45e-031.00e+005.1242235
GO:0004832valine-tRNA ligase activity1.64e-031.00e+009.253111
GO:0061383trabecula morphogenesis1.64e-031.00e+009.253111
GO:0002128tRNA nucleoside ribose methylation1.64e-031.00e+009.253111
GO:0008175tRNA methyltransferase activity1.64e-031.00e+009.253111
GO:0051435BH4 domain binding1.64e-031.00e+009.253111
GO:0006438valyl-tRNA aminoacylation1.64e-031.00e+009.253111
GO:0005654nucleoplasm1.87e-031.00e+002.064668876
GO:0006368transcription elongation from RNA polymerase II promoter3.18e-031.00e+004.5532852
GO:0005684U2-type spliceosomal complex3.27e-031.00e+008.253122
GO:0033688regulation of osteoblast proliferation3.27e-031.00e+008.253112
GO:0051123RNA polymerase II transcriptional preinitiation complex assembly3.27e-031.00e+008.253112
GO:0005681spliceosomal complex3.55e-031.00e+004.4722855
GO:0048011neurotrophin TRK receptor signaling pathway3.84e-031.00e+003.20238199
GO:0016032viral process4.35e-031.00e+002.512430428
GO:0005094Rho GDP-dissociation inhibitor activity4.91e-031.00e+007.668113
GO:0070006metalloaminopeptidase activity4.91e-031.00e+007.668113
GO:0006928cellular component movement5.70e-031.00e+004.1242670
GO:0001649osteoblast differentiation6.35e-031.00e+004.0442574
GO:0036089cleavage furrow formation6.54e-031.00e+007.253114
GO:0010815bradykinin catabolic process6.54e-031.00e+007.253114
GO:0051056regulation of small GTPase mediated signal transduction6.68e-031.00e+004.0052276
GO:0005938cell cortex6.86e-031.00e+003.9872677
GO:0038027apolipoprotein A-I-mediated signaling pathway8.17e-031.00e+006.931115
GO:0070934CRD-mediated mRNA stabilization8.17e-031.00e+006.931125
GO:0043931ossification involved in bone maturation8.17e-031.00e+006.931115
GO:0005672transcription factor TFIIA complex8.17e-031.00e+006.931115
GO:2000323negative regulation of glucocorticoid receptor signaling pathway8.17e-031.00e+006.931115
GO:0002161aminoacyl-tRNA editing activity8.17e-031.00e+006.931115
GO:0030027lamellipodium8.88e-031.00e+003.7942388
GO:0050847progesterone receptor signaling pathway9.79e-031.00e+006.668126
GO:0002181cytoplasmic translation9.79e-031.00e+006.668116
GO:0001055RNA polymerase II activity9.79e-031.00e+006.668136
GO:0043297apical junction assembly9.79e-031.00e+006.668116
GO:0070937CRD-mediated mRNA stability complex9.79e-031.00e+006.668126
GO:0005925focal adhesion1.01e-021.00e+002.699314282
GO:0051020GTPase binding1.14e-021.00e+006.446117
GO:0035615clathrin adaptor activity1.14e-021.00e+006.446117
GO:0007172signal complex assembly1.14e-021.00e+006.446117
GO:0007179transforming growth factor beta receptor signaling pathway1.29e-021.00e+003.51225107
GO:0090307spindle assembly involved in mitosis1.30e-021.00e+006.253128
GO:0006450regulation of translational fidelity1.30e-021.00e+006.253118
GO:0010944negative regulation of transcription by competitive promoter binding1.30e-021.00e+006.253118
GO:0010388cullin deneddylation1.30e-021.00e+006.253148
GO:0060396growth hormone receptor signaling pathway1.30e-021.00e+006.253118
GO:0043296apical junction complex1.30e-021.00e+006.253118
GO:0006397mRNA processing1.36e-021.00e+003.472212110
GO:0030122AP-2 adaptor complex1.47e-021.00e+006.083129
GO:0071354cellular response to interleukin-61.47e-021.00e+006.083119
GO:0030100regulation of endocytosis1.47e-021.00e+006.083119
GO:0048268clathrin coat assembly1.47e-021.00e+006.083129
GO:0034614cellular response to reactive oxygen species1.47e-021.00e+006.083129
GO:0072583clathrin-mediated endocytosis1.47e-021.00e+006.083119
GO:0003924GTPase activity1.58e-021.00e+003.35927119
GO:0005736DNA-directed RNA polymerase I complex1.63e-021.00e+005.9311410
GO:0005095GTPase inhibitor activity1.63e-021.00e+005.9311110
GO:0050919negative chemotaxis1.63e-021.00e+005.9311110
GO:0005246calcium channel regulator activity1.63e-021.00e+005.9311110
GO:0017166vinculin binding1.63e-021.00e+005.9311110
GO:0001054RNA polymerase I activity1.63e-021.00e+005.9311410
GO:0060766negative regulation of androgen receptor signaling pathway1.79e-021.00e+005.7941411
GO:0006184GTP catabolic process1.87e-021.00e+003.23127130
GO:0017025TBP-class protein binding1.95e-021.00e+005.6681112
GO:0005666DNA-directed RNA polymerase III complex2.11e-021.00e+005.5531313
GO:0005665DNA-directed RNA polymerase II, core complex2.11e-021.00e+005.5531313
GO:0001056RNA polymerase III activity2.11e-021.00e+005.5531313
GO:0042346positive regulation of NF-kappaB import into nucleus2.11e-021.00e+005.5531113
GO:0071526semaphorin-plexin signaling pathway2.11e-021.00e+005.5531113
GO:0007173epidermal growth factor receptor signaling pathway2.21e-021.00e+003.10425142
GO:0006386termination of RNA polymerase III transcription2.27e-021.00e+005.4461314
GO:0006385transcription elongation from RNA polymerase III promoter2.27e-021.00e+005.4461314
GO:0016575histone deacetylation2.27e-021.00e+005.4461214
GO:0004177aminopeptidase activity2.27e-021.00e+005.4461314
GO:0000188inactivation of MAPK activity2.43e-021.00e+005.3471115
GO:0032467positive regulation of cytokinesis2.59e-021.00e+005.2531116
GO:0017022myosin binding2.59e-021.00e+005.2531216
GO:0030532small nuclear ribonucleoprotein complex2.75e-021.00e+005.1661117
GO:0006367transcription initiation from RNA polymerase II promoter2.79e-021.00e+002.922218161
GO:0003899DNA-directed RNA polymerase activity2.91e-021.00e+005.0831318
GO:0005515protein binding2.96e-021.00e+000.703111984124
GO:0048041focal adhesion assembly3.07e-021.00e+005.0051119
GO:0036464cytoplasmic ribonucleoprotein granule3.07e-021.00e+005.0051119
GO:0007264small GTPase mediated signal transduction3.22e-021.00e+002.81028174
GO:0030032lamellipodium assembly3.23e-021.00e+004.9311220
GO:0071377cellular response to glucagon stimulus3.23e-021.00e+004.9311220
GO:0071897DNA biosynthetic process3.23e-021.00e+004.9311220
GO:0050690regulation of defense response to virus by virus3.55e-021.00e+004.7941122
GO:0005875microtubule associated complex3.55e-021.00e+004.7941122
GO:0048754branching morphogenesis of an epithelial tube3.71e-021.00e+004.7301123
GO:0001103RNA polymerase II repressing transcription factor binding3.71e-021.00e+004.7301223
GO:0032880regulation of protein localization3.71e-021.00e+004.7301123
GO:0001772immunological synapse3.71e-021.00e+004.7301223
GO:0030669clathrin-coated endocytic vesicle membrane3.71e-021.00e+004.7301123
GO:0005856cytoskeleton3.78e-021.00e+002.68428190
GO:0007162negative regulation of cell adhesion3.86e-021.00e+004.6681224
GO:00063707-methylguanosine mRNA capping3.86e-021.00e+004.6681524
GO:0008180COP9 signalosome3.86e-021.00e+004.6681624
GO:0034446substrate adhesion-dependent cell spreading4.02e-021.00e+004.6101225
GO:0030145manganese ion binding4.18e-021.00e+004.5531326
GO:0051496positive regulation of stress fiber assembly4.18e-021.00e+004.5531226
GO:0006360transcription from RNA polymerase I promoter4.34e-021.00e+004.4991427
GO:0042059negative regulation of epidermal growth factor receptor signaling pathway4.49e-021.00e+004.4461228
GO:0006418tRNA aminoacylation for protein translation4.65e-021.00e+004.3951429
GO:0006383transcription from RNA polymerase III promoter4.65e-021.00e+004.3951629
GO:0007268synaptic transmission4.69e-021.00e+002.51227214
GO:0032154cleavage furrow4.81e-021.00e+004.3471330
GO:0030054cell junction4.85e-021.00e+002.48525218
GO:0021762substantia nigra development5.43e-021.00e+004.1661134
GO:0007254JNK cascade5.43e-021.00e+004.1661134
GO:0008565protein transporter activity5.59e-021.00e+004.1241235
GO:0050434positive regulation of viral transcription5.59e-021.00e+004.1241535
GO:0044297cell body5.59e-021.00e+004.1241535
GO:0007411axon guidance5.63e-021.00e+002.36528237
GO:0005829cytosol5.64e-021.00e+001.0356881787
GO:0030334regulation of cell migration5.74e-021.00e+004.0831236
GO:0030666endocytic vesicle membrane5.74e-021.00e+004.0831136
GO:0003723RNA binding6.06e-021.00e+002.305222247
GO:0006396RNA processing6.36e-021.00e+003.9311440
GO:0006283transcription-coupled nucleotide-excision repair6.36e-021.00e+003.9311640
GO:0008013beta-catenin binding7.13e-021.00e+003.7621345
GO:0001725stress fiber7.28e-021.00e+003.7301646
GO:0032481positive regulation of type I interferon production7.59e-021.00e+003.6681348
GO:0006289nucleotide-excision repair8.35e-021.00e+003.5251653
GO:0045666positive regulation of neuron differentiation8.35e-021.00e+003.5251353
GO:0034329cell junction assembly8.35e-021.00e+003.5251253
GO:0006936muscle contraction8.50e-021.00e+003.4991554
GO:0042826histone deacetylase binding9.10e-021.00e+003.3951558
GO:0030336negative regulation of cell migration9.40e-021.00e+003.3471360
GO:0007010cytoskeleton organization9.55e-021.00e+003.3231461
GO:0000187activation of MAPK activity9.85e-021.00e+003.2761363
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II9.99e-021.00e+003.2531364
GO:0006112energy reserve metabolic process1.01e-011.00e+003.2311365
GO:0007229integrin-mediated signaling pathway1.03e-011.00e+003.2091166
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activity1.04e-011.00e+003.1871567
GO:0005178integrin binding1.06e-011.00e+003.1661368
GO:0005096GTPase activator activity1.06e-011.00e+003.1661268
GO:0006366transcription from RNA polymerase II promoter1.06e-011.00e+001.840223341
GO:0008360regulation of cell shape1.09e-011.00e+003.1241370
GO:0030308negative regulation of cell growth1.09e-011.00e+003.1241370
GO:0030496midbody1.13e-011.00e+003.0641673
GO:0070062extracellular vesicular exosome1.16e-011.00e+000.8955511641
GO:0030529ribonucleoprotein complex1.26e-011.00e+002.8961582
GO:0005215transporter activity1.26e-011.00e+002.8961582
GO:0048015phosphatidylinositol-mediated signaling1.28e-011.00e+002.8781283
GO:0031982vesicle1.34e-011.00e+002.8101287
GO:0018108peptidyl-tyrosine phosphorylation1.36e-011.00e+002.7781289
GO:0006886intracellular protein transport1.36e-011.00e+002.7781289
GO:0030036actin cytoskeleton organization1.38e-011.00e+002.7621490
GO:0044822poly(A) RNA binding1.38e-011.00e+001.196345799
GO:0042803protein homodimerization activity1.54e-011.00e+001.512213428
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling1.63e-011.00e+002.49912108
GO:0043547positive regulation of GTPase activity1.69e-011.00e+002.44612112
GO:0042981regulation of apoptotic process1.69e-011.00e+002.44614112
GO:0007049cell cycle1.73e-011.00e+002.40818115
GO:0005765lysosomal membrane1.80e-011.00e+002.34711120
GO:0032403protein complex binding1.93e-011.00e+002.23115130
GO:0030168platelet activation2.08e-011.00e+002.11415141
GO:0044212transcription regulatory region DNA binding2.10e-011.00e+002.094113143
GO:0004871signal transducer activity2.17e-011.00e+002.04414148
GO:0005874microtubule2.36e-011.00e+001.905110163
GO:0005737cytoplasm2.45e-011.00e+000.47661272633
GO:0005634nucleus2.60e-011.00e+000.39671583246
GO:0003713transcription coactivator activity2.63e-011.00e+001.730121184
GO:0007165signal transduction2.69e-011.00e+000.982224618
GO:0005743mitochondrial inner membrane2.78e-011.00e+001.63119197
GO:0005525GTP binding2.78e-011.00e+001.631112197
GO:0006281DNA repair2.86e-011.00e+001.588124203
GO:0008134transcription factor binding2.93e-011.00e+001.546110209
GO:0005739mitochondrion2.94e-011.00e+000.889232659
GO:0043234protein complex2.94e-011.00e+001.539113210
GO:0019899enzyme binding2.94e-011.00e+001.53917210
GO:0007186G-protein coupled receptor signaling pathway3.16e-011.00e+001.41414229
GO:0016020membrane3.16e-011.00e+000.6013561207
GO:0019901protein kinase binding3.20e-011.00e+001.39518232
GO:0005730nucleolus3.21e-011.00e+000.5893741217
GO:0007155cell adhesion3.33e-011.00e+001.32318244
GO:0005886plasma membrane3.33e-011.00e+000.4534461784
GO:0008270zinc ion binding3.37e-011.00e+000.748239727
GO:0006508proteolysis3.55e-011.00e+001.209111264
GO:0046982protein heterodimerization activity3.56e-011.00e+001.204111265
GO:0008285negative regulation of cell proliferation3.69e-011.00e+001.140111277
GO:0009986cell surface3.84e-011.00e+001.06915291
GO:0045892negative regulation of transcription, DNA-templated4.10e-011.00e+000.945117317
GO:0043066negative regulation of apoptotic process4.15e-011.00e+000.92218322
GO:0007596blood coagulation4.32e-011.00e+000.848113339
GO:0005524ATP binding4.37e-011.00e+000.453237892
GO:0048471perinuclear region of cytoplasm4.37e-011.00e+000.827111344
GO:0045893positive regulation of transcription, DNA-templated4.68e-011.00e+000.695121377
GO:0003677DNA binding4.69e-011.00e+000.366252947
GO:0045087innate immune response5.32e-011.00e+000.433112452
GO:0000122negative regulation of transcription from RNA polymerase II promoter5.35e-011.00e+000.421129456
GO:0005887integral component of plasma membrane6.22e-011.00e+000.08618575
GO:0045944positive regulation of transcription from RNA polymerase II promoter6.65e-011.00e+00-0.078129644
GO:0005615extracellular space6.69e-011.00e+00-0.093115651
GO:0006355regulation of transcription, DNA-templated7.04e-011.00e+00-0.228131715
GO:0044281small molecule metabolic process7.65e-011.00e+00-0.468135844