reg-snw-26263

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.369	3.64e-08	1.51e-02	1.26e-02

chia-screen-data-Fav-reg-snw-26263 subnetwork

Genes (14)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
NDUFA4L2	56901	44	-2.477	2.459	21	-	Yes	-
EIF2S2	8894	40	-2.999	2.459	22	-	Yes	Yes
NCBP1	4686	41	-2.510	2.459	44	-	Yes	Yes
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
KIAA1551	55196	6	-1.852	2.369	35	-	-	-
ACTR5	79913	4	-1.887	2.369	19	-	-	-
VARS	7407	60	-2.366	2.689	124	TF	Yes	-
CENPQ	55166	20	-2.137	2.459	16	-	Yes	-
CCT7	10574	40	-2.335	2.459	38	-	Yes	-
HSPD1	3329	2	-1.852	2.369	39	-	-	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
POLH	5429	36	-2.586	2.459	24	-	Yes	Yes
PSPH	5723	14	-2.063	2.387	11	-	Yes	-
[ FBXO22 ]	26263	36	-1.739	2.459	208	TF	-	-

Interactions (14)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
FBXO22	26263	ACTR5	79913	pd	>	reg.ITFP.txt: no annot
VARS	7407	FBXO22	26263	pd	<>	reg.ITFP.txt: no annot
PHB	5245	VARS	7407	pd	<	reg.ITFP.txt: no annot
PHB	5245	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
FBXO22	26263	NDUFA4L2	56901	pd	>	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
CCT7	10574	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
HSPD1	3329	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
POLH	5429	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
FBXO22	26263	CENPQ	55166	pd	>	reg.ITFP.txt: no annot
NCBP1	4686	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
EIF2S2	8894	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
FBXO22	26263	KIAA1551	55196	pd	>	reg.ITFP.txt: no annot
PSPH	5723	FBXO22	26263	pd	<	reg.ITFP.txt: no annot

Related GO terms (174)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0004832	valine-tRNA ligase activity	1.43e-03	1.00e+00	9.446	1	1	1
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	1.43e-03	1.00e+00	9.446	1	1	1
GO:0048291	isotype switching to IgG isotypes	1.43e-03	1.00e+00	9.446	1	1	1
GO:0006438	valyl-tRNA aminoacylation	1.43e-03	1.00e+00	9.446	1	1	1
GO:0002368	B cell cytokine production	1.43e-03	1.00e+00	9.446	1	1	1
GO:0005739	mitochondrion	1.65e-03	1.00e+00	2.404	5	32	659
GO:0006458	'de novo' protein folding	2.87e-03	1.00e+00	8.446	1	1	2
GO:0048742	regulation of skeletal muscle fiber development	2.87e-03	1.00e+00	8.446	1	1	2
GO:0004647	phosphoserine phosphatase activity	2.87e-03	1.00e+00	8.446	1	1	2
GO:0005846	nuclear cap binding complex	2.87e-03	1.00e+00	8.446	1	1	2
GO:0002176	male germ cell proliferation	2.87e-03	1.00e+00	8.446	1	1	2
GO:0005850	eukaryotic translation initiation factor 2 complex	4.30e-03	1.00e+00	7.861	1	2	3
GO:0003688	DNA replication origin binding	4.30e-03	1.00e+00	7.861	1	1	3
GO:0046696	lipopolysaccharide receptor complex	4.30e-03	1.00e+00	7.861	1	1	3
GO:0030135	coated vesicle	4.30e-03	1.00e+00	7.861	1	1	3
GO:0006563	L-serine metabolic process	4.30e-03	1.00e+00	7.861	1	1	3
GO:0051082	unfolded protein binding	4.36e-03	1.00e+00	4.317	2	5	70
GO:0045292	mRNA cis splicing, via spliceosome	5.72e-03	1.00e+00	7.446	1	1	4
GO:0031442	positive regulation of mRNA 3'-end processing	5.72e-03	1.00e+00	7.446	1	1	4
GO:0006290	pyrimidine dimer repair	5.72e-03	1.00e+00	7.446	1	2	4
GO:0006564	L-serine biosynthetic process	5.72e-03	1.00e+00	7.446	1	1	4
GO:0005829	cytosol	7.00e-03	1.00e+00	1.450	7	88	1787
GO:0006282	regulation of DNA repair	7.15e-03	1.00e+00	7.124	1	2	5
GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex	7.15e-03	1.00e+00	7.124	1	2	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	7.15e-03	1.00e+00	7.124	1	1	5
GO:0002161	aminoacyl-tRNA editing activity	7.15e-03	1.00e+00	7.124	1	1	5
GO:0050847	progesterone receptor signaling pathway	8.57e-03	1.00e+00	6.861	1	2	6
GO:0070914	UV-damage excision repair	8.57e-03	1.00e+00	6.861	1	1	6
GO:0043032	positive regulation of macrophage activation	8.57e-03	1.00e+00	6.861	1	1	6
GO:0002199	zona pellucida receptor complex	1.00e-02	1.00e+00	6.639	1	4	7
GO:0000731	DNA synthesis involved in DNA repair	1.00e-02	1.00e+00	6.639	1	1	7
GO:0006301	postreplication repair	1.00e-02	1.00e+00	6.639	1	2	7
GO:0000339	RNA cap binding	1.00e-02	1.00e+00	6.639	1	1	7
GO:0005832	chaperonin-containing T-complex	1.00e-02	1.00e+00	6.639	1	4	7
GO:0005845	mRNA cap binding complex	1.14e-02	1.00e+00	6.446	1	1	8
GO:0006450	regulation of translational fidelity	1.14e-02	1.00e+00	6.446	1	1	8
GO:0032727	positive regulation of interferon-alpha production	1.14e-02	1.00e+00	6.446	1	1	8
GO:0010944	negative regulation of transcription by competitive promoter binding	1.14e-02	1.00e+00	6.446	1	1	8
GO:0031011	Ino80 complex	1.14e-02	1.00e+00	6.446	1	3	8
GO:0010388	cullin deneddylation	1.14e-02	1.00e+00	6.446	1	4	8
GO:0051604	protein maturation	1.14e-02	1.00e+00	6.446	1	1	8
GO:0010225	response to UV-C	1.28e-02	1.00e+00	6.276	1	2	9
GO:0006379	mRNA cleavage	1.28e-02	1.00e+00	6.276	1	2	9
GO:0071354	cellular response to interleukin-6	1.28e-02	1.00e+00	6.276	1	1	9
GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.28e-02	1.00e+00	6.276	1	2	9
GO:0001530	lipopolysaccharide binding	1.28e-02	1.00e+00	6.276	1	1	9
GO:0005095	GTPase inhibitor activity	1.43e-02	1.00e+00	6.124	1	1	10
GO:0042026	protein refolding	1.43e-02	1.00e+00	6.124	1	1	10
GO:0051131	chaperone-mediated protein complex assembly	1.43e-02	1.00e+00	6.124	1	3	10
GO:0060766	negative regulation of androgen receptor signaling pathway	1.57e-02	1.00e+00	5.987	1	4	11
GO:0008652	cellular amino acid biosynthetic process	1.57e-02	1.00e+00	5.987	1	2	11
GO:0008334	histone mRNA metabolic process	1.57e-02	1.00e+00	5.987	1	1	11
GO:0005737	cytoplasm	1.65e-02	1.00e+00	1.084	8	127	2633
GO:0032733	positive regulation of interleukin-10 production	1.85e-02	1.00e+00	5.746	1	2	13
GO:0050870	positive regulation of T cell activation	1.99e-02	1.00e+00	5.639	1	1	14
GO:0016575	histone deacetylation	1.99e-02	1.00e+00	5.639	1	2	14
GO:0008135	translation factor activity, nucleic acid binding	2.13e-02	1.00e+00	5.539	1	4	15
GO:0000188	inactivation of MAPK activity	2.13e-02	1.00e+00	5.539	1	1	15
GO:0007339	binding of sperm to zona pellucida	2.13e-02	1.00e+00	5.539	1	4	15
GO:0003887	DNA-directed DNA polymerase activity	2.27e-02	1.00e+00	5.446	1	2	16
GO:0042113	B cell activation	2.27e-02	1.00e+00	5.446	1	1	16
GO:0042100	B cell proliferation	2.41e-02	1.00e+00	5.359	1	1	17
GO:0031667	response to nutrient levels	2.41e-02	1.00e+00	5.359	1	2	17
GO:0031047	gene silencing by RNA	2.55e-02	1.00e+00	5.276	1	2	18
GO:0033574	response to testosterone	2.55e-02	1.00e+00	5.276	1	1	18
GO:0006913	nucleocytoplasmic transport	2.83e-02	1.00e+00	5.124	1	2	20
GO:0034080	CENP-A containing nucleosome assembly	2.83e-02	1.00e+00	5.124	1	2	20
GO:0071897	DNA biosynthetic process	2.83e-02	1.00e+00	5.124	1	2	20
GO:0032735	positive regulation of interleukin-12 production	2.83e-02	1.00e+00	5.124	1	1	20
GO:0034660	ncRNA metabolic process	2.83e-02	1.00e+00	5.124	1	1	20
GO:0005654	nucleoplasm	3.10e-02	1.00e+00	1.671	4	68	876
GO:0051084	'de novo' posttranslational protein folding	3.11e-02	1.00e+00	4.987	1	4	22
GO:0000387	spliceosomal snRNP assembly	3.11e-02	1.00e+00	4.987	1	1	22
GO:0005743	mitochondrial inner membrane	3.14e-02	1.00e+00	2.824	2	9	197
GO:0006370	7-methylguanosine mRNA capping	3.39e-02	1.00e+00	4.861	1	5	24
GO:0008180	COP9 signalosome	3.39e-02	1.00e+00	4.861	1	6	24
GO:0009267	cellular response to starvation	3.67e-02	1.00e+00	4.746	1	1	26
GO:0010467	gene expression	3.79e-02	1.00e+00	1.968	3	49	535
GO:0032755	positive regulation of interleukin-6 production	3.80e-02	1.00e+00	4.691	1	1	27
GO:0032729	positive regulation of interferon-gamma production	3.94e-02	1.00e+00	4.639	1	1	28
GO:0006418	tRNA aminoacylation for protein translation	4.08e-02	1.00e+00	4.588	1	4	29
GO:0006446	regulation of translational initiation	4.08e-02	1.00e+00	4.588	1	2	29
GO:0045111	intermediate filament cytoskeleton	4.36e-02	1.00e+00	4.492	1	3	31
GO:0042110	T cell activation	4.63e-02	1.00e+00	4.402	1	2	33
GO:0003723	RNA binding	4.75e-02	1.00e+00	2.498	2	22	247
GO:0007254	JNK cascade	4.77e-02	1.00e+00	4.359	1	1	34
GO:0050434	positive regulation of viral transcription	4.91e-02	1.00e+00	4.317	1	5	35
GO:0006986	response to unfolded protein	4.91e-02	1.00e+00	4.317	1	1	35
GO:0031124	mRNA 3'-end processing	4.91e-02	1.00e+00	4.317	1	4	35
GO:0044297	cell body	4.91e-02	1.00e+00	4.317	1	5	35
GO:0003743	translation initiation factor activity	5.18e-02	1.00e+00	4.237	1	8	37
GO:0005905	coated pit	5.18e-02	1.00e+00	4.237	1	2	37
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	5.32e-02	1.00e+00	4.198	1	4	38
GO:0006369	termination of RNA polymerase II transcription	5.32e-02	1.00e+00	4.198	1	5	38
GO:0000775	chromosome, centromeric region	5.72e-02	1.00e+00	4.088	1	6	41
GO:0003684	damaged DNA binding	5.72e-02	1.00e+00	4.088	1	1	41
GO:0030141	secretory granule	6.13e-02	1.00e+00	3.987	1	2	44
GO:0006406	mRNA export from nucleus	6.13e-02	1.00e+00	3.987	1	7	44
GO:0051087	chaperone binding	6.27e-02	1.00e+00	3.954	1	3	45
GO:0003725	double-stranded RNA binding	6.27e-02	1.00e+00	3.954	1	2	45
GO:0002039	p53 binding	6.27e-02	1.00e+00	3.954	1	4	45
GO:0009612	response to mechanical stimulus	6.40e-02	1.00e+00	3.922	1	2	46
GO:0006310	DNA recombination	6.94e-02	1.00e+00	3.802	1	8	50
GO:0006334	nucleosome assembly	7.07e-02	1.00e+00	3.774	1	4	51
GO:0006368	transcription elongation from RNA polymerase II promoter	7.21e-02	1.00e+00	3.746	1	8	52
GO:0006302	double-strand break repair	7.21e-02	1.00e+00	3.746	1	5	52
GO:0016311	dephosphorylation	7.61e-02	1.00e+00	3.665	1	3	55
GO:0008584	male gonad development	7.87e-02	1.00e+00	3.613	1	1	57
GO:0003697	single-stranded DNA binding	7.87e-02	1.00e+00	3.613	1	4	57
GO:0042826	histone deacetylase binding	8.01e-02	1.00e+00	3.588	1	5	58
GO:0006464	cellular protein modification process	8.40e-02	1.00e+00	3.515	1	4	61
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	8.40e-02	1.00e+00	3.515	1	4	61
GO:0050821	protein stabilization	8.80e-02	1.00e+00	3.446	1	3	64
GO:0030018	Z disc	8.80e-02	1.00e+00	3.446	1	3	64
GO:0044267	cellular protein metabolic process	8.86e-02	1.00e+00	1.987	2	14	352
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	9.19e-02	1.00e+00	3.380	1	1	67
GO:0030308	negative regulation of cell growth	9.59e-02	1.00e+00	3.317	1	3	70
GO:0001649	osteoblast differentiation	1.01e-01	1.00e+00	3.237	1	5	74
GO:0044822	poly(A) RNA binding	1.01e-01	1.00e+00	1.389	3	45	799
GO:0030529	ribonucleoprotein complex	1.11e-01	1.00e+00	3.088	1	5	82
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.14e-01	1.00e+00	3.054	1	5	84
GO:0016032	viral process	1.23e-01	1.00e+00	1.705	2	30	428
GO:0000209	protein polyubiquitination	1.24e-01	1.00e+00	2.922	1	6	92
GO:0006511	ubiquitin-dependent protein catabolic process	1.24e-01	1.00e+00	2.922	1	6	92
GO:0006260	DNA replication	1.27e-01	1.00e+00	2.891	1	9	94
GO:0005524	ATP binding	1.30e-01	1.00e+00	1.230	3	37	892
GO:0006457	protein folding	1.31e-01	1.00e+00	2.846	1	5	97
GO:0006413	translational initiation	1.33e-01	1.00e+00	2.817	1	6	99
GO:0016887	ATPase activity	1.34e-01	1.00e+00	2.802	1	5	100
GO:0034641	cellular nitrogen compound metabolic process	1.41e-01	1.00e+00	2.732	1	5	105
GO:0005769	early endosome	1.46e-01	1.00e+00	2.678	1	3	109
GO:0042981	regulation of apoptotic process	1.49e-01	1.00e+00	2.639	1	4	112
GO:0043005	neuron projection	1.50e-01	1.00e+00	2.626	1	6	113
GO:0000287	magnesium ion binding	1.53e-01	1.00e+00	2.601	1	4	115
GO:0007049	cell cycle	1.53e-01	1.00e+00	2.601	1	8	115
GO:0000398	mRNA splicing, via spliceosome	1.69e-01	1.00e+00	2.446	1	15	128
GO:0005759	mitochondrial matrix	1.82e-01	1.00e+00	2.327	1	7	139
GO:0044212	transcription regulatory region DNA binding	1.87e-01	1.00e+00	2.286	1	13	143
GO:0005515	protein binding	1.94e-01	1.00e+00	0.436	8	198	4124
GO:0001701	in utero embryonic development	2.00e-01	1.00e+00	2.179	1	7	154
GO:0005874	microtubule	2.10e-01	1.00e+00	2.097	1	10	163
GO:0008380	RNA splicing	2.12e-01	1.00e+00	2.080	1	21	165
GO:0016071	mRNA metabolic process	2.18e-01	1.00e+00	2.037	1	10	170
GO:0006412	translation	2.27e-01	1.00e+00	1.970	1	12	178
GO:0004842	ubiquitin-protein transferase activity	2.28e-01	1.00e+00	1.962	1	17	179
GO:0016070	RNA metabolic process	2.38e-01	1.00e+00	1.891	1	10	188
GO:0043065	positive regulation of apoptotic process	2.54e-01	1.00e+00	1.788	1	7	202
GO:0006281	DNA repair	2.55e-01	1.00e+00	1.781	1	24	203
GO:0043234	protein complex	2.63e-01	1.00e+00	1.732	1	13	210
GO:0019899	enzyme binding	2.63e-01	1.00e+00	1.732	1	7	210
GO:0006200	ATP catabolic process	2.72e-01	1.00e+00	1.671	1	13	219
GO:0006355	regulation of transcription, DNA-templated	2.74e-01	1.00e+00	0.964	2	31	715
GO:0005634	nucleus	3.07e-01	1.00e+00	0.367	6	158	3246
GO:0008285	negative regulation of cell proliferation	3.32e-01	1.00e+00	1.332	1	11	277
GO:0009986	cell surface	3.45e-01	1.00e+00	1.261	1	5	291
GO:0000278	mitotic cell cycle	3.67e-01	1.00e+00	1.151	1	28	314
GO:0045892	negative regulation of transcription, DNA-templated	3.70e-01	1.00e+00	1.138	1	17	317
GO:0043066	negative regulation of apoptotic process	3.75e-01	1.00e+00	1.115	1	8	322
GO:0006366	transcription from RNA polymerase II promoter	3.92e-01	1.00e+00	1.032	1	23	341
GO:0046872	metal ion binding	3.93e-01	1.00e+00	0.579	2	24	934
GO:0005509	calcium ion binding	4.01e-01	1.00e+00	0.991	1	9	351
GO:0042802	identical protein binding	4.04e-01	1.00e+00	0.978	1	15	354
GO:0045893	positive regulation of transcription, DNA-templated	4.24e-01	1.00e+00	0.888	1	21	377
GO:0070062	extracellular vesicular exosome	4.26e-01	1.00e+00	0.351	3	51	1641
GO:0042803	protein homodimerization activity	4.66e-01	1.00e+00	0.705	1	13	428
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	4.88e-01	1.00e+00	0.613	1	29	456
GO:0016020	membrane	5.31e-01	1.00e+00	0.209	2	56	1207
GO:0005730	nucleolus	5.36e-01	1.00e+00	0.197	2	74	1217
GO:0005887	integral component of plasma membrane	5.73e-01	1.00e+00	0.279	1	8	575
GO:0007165	signal transduction	6.00e-01	1.00e+00	0.175	1	24	618
GO:0005615	extracellular space	6.20e-01	1.00e+00	0.100	1	15	651
GO:0044281	small molecule metabolic process	7.18e-01	1.00e+00	-0.275	1	35	844
GO:0005886	plasma membrane	7.55e-01	1.00e+00	-0.355	2	46	1784
GO:0006351	transcription, DNA-templated	8.05e-01	1.00e+00	-0.625	1	47	1076

chia-Fav

reg-snw-26263

Statistics

Genes (14)

Interactions (14)

Related GO terms (174)